CN115812823A - Tabletting candy containing clove volatile oil and preparation process thereof - Google Patents
Tabletting candy containing clove volatile oil and preparation process thereof Download PDFInfo
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- CN115812823A CN115812823A CN202211509412.9A CN202211509412A CN115812823A CN 115812823 A CN115812823 A CN 115812823A CN 202211509412 A CN202211509412 A CN 202211509412A CN 115812823 A CN115812823 A CN 115812823A
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- 235000009508 confectionery Nutrition 0.000 title claims abstract description 50
- 239000000341 volatile oil Substances 0.000 title claims abstract description 30
- 244000223014 Syzygium aromaticum Species 0.000 title claims abstract description 29
- 235000016639 Syzygium aromaticum Nutrition 0.000 title claims abstract description 29
- 238000002360 preparation method Methods 0.000 title claims description 12
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims abstract description 40
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims abstract description 22
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims abstract description 22
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims abstract description 22
- 239000008108 microcrystalline cellulose Substances 0.000 claims abstract description 22
- 229940016286 microcrystalline cellulose Drugs 0.000 claims abstract description 22
- 239000000600 sorbitol Substances 0.000 claims abstract description 22
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract description 20
- 235000019359 magnesium stearate Nutrition 0.000 claims abstract description 20
- 229910002012 Aerosil® Inorganic materials 0.000 claims abstract description 18
- OABQFEHDVMFLLE-UHFFFAOYSA-L calcium;dihydrogen phosphate;dihydrate Chemical compound O.O.[Ca+2].OP(O)([O-])=O.OP(O)([O-])=O OABQFEHDVMFLLE-UHFFFAOYSA-L 0.000 claims abstract description 5
- 238000000576 coating method Methods 0.000 claims description 63
- 238000002156 mixing Methods 0.000 claims description 62
- 239000011248 coating agent Substances 0.000 claims description 59
- 239000002994 raw material Substances 0.000 claims description 45
- 239000008187 granular material Substances 0.000 claims description 36
- 238000001035 drying Methods 0.000 claims description 27
- 238000005469 granulation Methods 0.000 claims description 22
- 230000003179 granulation Effects 0.000 claims description 22
- 239000000463 material Substances 0.000 claims description 21
- 239000000843 powder Substances 0.000 claims description 20
- 238000003756 stirring Methods 0.000 claims description 20
- 238000004806 packaging method and process Methods 0.000 claims description 19
- 238000010438 heat treatment Methods 0.000 claims description 16
- XAAHAAMILDNBPS-UHFFFAOYSA-L calcium hydrogenphosphate dihydrate Chemical compound O.O.[Ca+2].OP([O-])([O-])=O XAAHAAMILDNBPS-UHFFFAOYSA-L 0.000 claims description 15
- 239000002131 composite material Substances 0.000 claims description 15
- 235000019700 dicalcium phosphate Nutrition 0.000 claims description 15
- 239000005022 packaging material Substances 0.000 claims description 15
- 238000003825 pressing Methods 0.000 claims description 15
- 238000007873 sieving Methods 0.000 claims description 15
- 239000007787 solid Substances 0.000 claims description 13
- 239000002245 particle Substances 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 9
- 238000005550 wet granulation Methods 0.000 claims description 9
- 238000007580 dry-mixing Methods 0.000 claims description 8
- 238000005096 rolling process Methods 0.000 claims description 8
- 238000010008 shearing Methods 0.000 claims description 8
- 230000007306 turnover Effects 0.000 claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 239000000080 wetting agent Substances 0.000 claims description 6
- 235000010356 sorbitol Nutrition 0.000 claims description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 4
- 238000000889 atomisation Methods 0.000 claims description 4
- 238000009835 boiling Methods 0.000 claims description 4
- 239000008213 purified water Substances 0.000 claims description 4
- 238000005070 sampling Methods 0.000 claims description 4
- 239000002002 slurry Substances 0.000 claims description 4
- 229960002920 sorbitol Drugs 0.000 claims description 4
- 239000007921 spray Substances 0.000 claims description 4
- 238000005507 spraying Methods 0.000 claims description 4
- 238000004519 manufacturing process Methods 0.000 claims description 2
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims 1
- 238000012545 processing Methods 0.000 abstract description 4
- 238000005516 engineering process Methods 0.000 abstract description 3
- 239000000741 silica gel Substances 0.000 abstract description 2
- 229910021487 silica fume Inorganic materials 0.000 abstract 1
- 238000011156 evaluation Methods 0.000 description 7
- 238000005259 measurement Methods 0.000 description 5
- 230000001953 sensory effect Effects 0.000 description 5
- 230000000694 effects Effects 0.000 description 3
- 241000193830 Bacillus <bacterium> Species 0.000 description 2
- 241000588724 Escherichia coli Species 0.000 description 2
- 241000590002 Helicobacter pylori Species 0.000 description 2
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 2
- 241000191940 Staphylococcus Species 0.000 description 2
- 241000194017 Streptococcus Species 0.000 description 2
- 208000037386 Typhoid Diseases 0.000 description 2
- RRAFCDWBNXTKKO-UHFFFAOYSA-N eugenol Chemical compound COC1=CC(CC=C)=CC=C1O RRAFCDWBNXTKKO-UHFFFAOYSA-N 0.000 description 2
- 239000000796 flavoring agent Substances 0.000 description 2
- 235000019634 flavors Nutrition 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 229940037467 helicobacter pylori Drugs 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 201000008297 typhoid fever Diseases 0.000 description 2
- OYPRJOBELJOOCE-IGMARMGPSA-N Calcium-40 Chemical group [40Ca] OYPRJOBELJOOCE-IGMARMGPSA-N 0.000 description 1
- NPBVQXIMTZKSBA-UHFFFAOYSA-N Chavibetol Natural products COC1=CC=C(CC=C)C=C1O NPBVQXIMTZKSBA-UHFFFAOYSA-N 0.000 description 1
- 239000005770 Eugenol Substances 0.000 description 1
- 241000628997 Flos Species 0.000 description 1
- UVMRYBDEERADNV-UHFFFAOYSA-N Pseudoeugenol Natural products COC1=CC(C(C)=C)=CC=C1O UVMRYBDEERADNV-UHFFFAOYSA-N 0.000 description 1
- 208000019790 abdominal distention Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000011362 coarse particle Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 238000007908 dry granulation Methods 0.000 description 1
- 229960002217 eugenol Drugs 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 239000002075 main ingredient Substances 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
Classifications
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Medicinal Preparation (AREA)
Abstract
The invention relates to a tablet candy containing clove volatile oil and a processing technology thereof, and the tablet candy comprises the following components in parts by weight: 10 to 50 portions of sorbitol, 2 to 12 portions of clove volatile oil, 5 to 25 portions of calcium dihydrogen phosphate dihydrate, 10 to 50 portions of microcrystalline cellulose, 8 to 18 portions of micro silica gel and 0.5 to 2.5 portions of magnesium stearate. The formula of the tablet candy is optimized, and when the sorbitol and the microcrystalline cellulose are 1:1, the prepared tablet candy is fine and smooth in taste, granular in feeling, cool, proper in sweetness, smooth and complete in appearance, and has a small amount of spots and no tablets; when the proportion of the clove volatile oil and the aerosil is between 1:9 and 1.25.
Description
Technical Field
The invention relates to a pressed candy containing clove volatile oil and a processing technology thereof, which are used for preventing and controlling helicobacter pylori, staphylococcus, streptococcus, escherichia coli, typhoid bacillus, pseudomonas aeruginosa and the like.
Background
The essential oil of flos Caryophylli contains eugenol as main ingredient, and has effects of relieving abdominal distention, increasing gastric secretion, and increasing digestion ability. The clove volatile oil has inhibitory effect on helicobacter pylori, staphylococcus, streptococcus, escherichia coli, typhoid bacillus, pseudomonas aeruginosa, etc. Due to the influence of the special property (easy volatility) of the clove volatile oil, if a common formula and a granulation method (wet granulation or dry granulation) are adopted, the obtained particles have loose texture or uneven particle thickness distribution, coarse particles and fine particles are layered, and the pressed tablet candy is loose, and has hardness and brittleness which do not meet the requirements.
Disclosure of Invention
Aiming at the defects, the invention aims to provide a tabletting candy containing clove volatile oil and a processing technology thereof.
The invention provides the following technical scheme:
1. the tabletting candy containing clove volatile oil is characterized by comprising the following components in parts by weight:
2. a process for preparing a tabletted confectionery product according to claim 1, comprising the steps of:
s1, proportioning: preparing raw materials in proportion;
s2, crushing: pre-crushing granular raw materials, and sieving all the raw materials with a 30-mesh sieve to obtain powder;
s3, granulation: adding sorbitol, part of calcium hydrogen phosphate dihydrate and part of microcrystalline cellulose into a high-speed wet mixing granulator, granulating by using a high-efficiency wet granulator, drying by using a fluidized bed, and finishing granules to obtain dry granules;
s4, total mixing: mixing the clove volatile oil, the superfine silica gel powder and the magnesium stearate with the granules obtained in the step S3;
s5, tabletting: adjusting the pressure of the tablet press to 30 kilonewtons and the rotating speed of the tablet press to 40 revolutions per minute to prepare tablet candies;
s6, coating a film coat: coating with a high-efficiency coating machine after tabletting to ensure that the surface of the tabletted candy is smooth, flat, fine and solid;
s7, packaging: the packaging material is high-density PE bottle or composite film pressing plate, and is sealed and packaged.
3. The preparation process according to claim 2, wherein the granulation comprises the following specific steps:
s31 dry mixing: adding sorbitol, microcrystalline cellulose and calcium dihydrogen phosphate dihydrate into a high-speed wet mixing granulator, and setting parameters as follows: stirring at 150 rpm, shearing at 500 rpm, and dry mixing for 5 min;
s32, wet granulation: setting parameters: stirring at 150 revolutions per minute and shearing at 900 revolutions per minute, starting a machine, adding the wetting agent in a spraying manner, continuing to operate for 5 minutes after the addition is finished, and determining a granulation end point according to the properties of the materials;
s33, material suction: setting the parameters of the fluidized bed: 35HZ of air exhaust and heating: setting the discharge parameters of a wet granulator at 50 ℃ for 300 seconds at bag shaking intervals: stirring for 25 revolutions per minute, performing wet granulation for 800 revolutions per minute, after setting, opening a discharge cabin door of the wet granulator and a feeding switch of the fluidized bed, and sucking materials in the wet granulator into the fluidized bed through a connecting pipe for boiling;
s34, drying: firstly, setting exhaust air 28HZ, and heating: shaking the bag at 50 ℃ for 90 seconds at an interval time, maintaining for 10 minutes, and then setting: exhausting air for 20HZ, and heating: shaking at 50 deg.C for 90 s at bag interval, maintaining for 20 min, stopping machine, sampling to determine water content, controlling water content to 5%, drying, stopping machine, discharging, and preparing for grading;
s35, finishing, namely connecting a fluidized bed bin with a matched lifting turnover machine, performing dry finishing after lifting turnover to obtain finished dry particles, and packaging and storing the finished dry particles by double-layer PE bags or transferring the mixed material bin by a material mixing machine to directly receive materials.
4. The process according to claim 3, wherein the ratio of wetting agent: a 10wt% ethanol solution, in a total amount of 270g, corresponding to 1000 tablets of tabletted candy.
5. The preparation process according to claim 4, wherein the whole dry granules, the clove volatile oil and the aerosil are sequentially added into a main mixer, and the mixer is started to set the following components: the rotating speed is 10 r/min, the mixing time is 5min, the machine is stopped, magnesium stearate with the amount of the prescription is added, the mixing is continued for 3 min, and the machine is stopped for blanking after the mixing is finished.
7. The process according to claim 2, wherein the tabletting comprises the steps of: adjusting the pressure of the tablet press to 5-40 kilonewtons, the rotating speed of the tablet press to 10-80 rpm, and checking the average tablet weight once every 15 min; check the single piece every 30min and take 10 pieces each time.
8. The preparation process of claim 2, wherein the coating comprises the following specific steps:
placing 6.14kg of purified water in a slurry preparation container, starting stirring to keep the solution in a vortex shape, slowly adding 1kg of brown coating powder, and continuously stirring for 45 minutes to obtain a coating solution;
putting the tablet core into a coating pan, intermittently rolling the pan body at the lowest speed, and preheating to the temperature of 37-40 ℃ of the tablet core.
9. The process of claim 8, wherein the coating process control data is: air inlet temperature: 70 +/-5 ℃; the atomization pressure is 0.4 +/-0.1 MPa; temperature of the slice bed: at 40 ℃; after coating, closing the spray gun, reducing the rotating speed, and drying the tablets for 10 minutes; confirming that the slices are completely dried, closing the air inlet heating system, and intermittently rolling the pot body until the temperature of the slice bed reaches the room temperature; the coated tablets were transferred to a defined container.
The invention has the beneficial effects that: the formula of the tablet candy is optimized, and when the sorbitol and the microcrystalline cellulose are 1:1, the prepared tablet candy is fine and smooth in taste, granular in feeling, cool, proper in sweetness, smooth and complete in appearance, and has a small amount of spots and no tablets; when the proportion of the clove volatile oil and the aerosil is between 1:9 and 1.25.
Detailed Description
The conception, the specific structure and the technical effects of the present invention will be clearly and completely described in the following with reference to the embodiments, so that the objects, the schemes and the effects of the present invention can be fully understood.
Sensory evaluation method
8 food industry research and development personnel or workers with food processing experience are randomly selected to form a sensory evaluation group, and the appearance, flavor and taste of the tabletted candies are used as evaluation indexes for evaluation. Product score = appearance score 0.2+ flavor score 0.4+ mouthfeel score 0.4. Specific sensory evaluation criteria are shown in table 1.
Table 1 is the sensory evaluation criteria for tabletted confections
Hardness and friability measurements
Measuring the hardness and friability of the tabletted candy by using a texture analyzer, and using a probe P/5; setting the test parameters as follows: the speed before measurement is 1.00mm/s; the speed of the middle measurement is 0.5mm/s; the speed after measurement is 10.00mm/s; the test distance is 2.5mm; the harvest parameters hardness and friability were determined by a texture analyzer. Each set of samples was run in parallel 8 times, and the mean was taken after the maxima and minima were removed.
Example 1:
s1, proportioning: preparing raw materials in proportion;
s2, crushing: pre-crushing granular raw materials, and sieving all the raw materials by a 30-mesh sieve to obtain powder;
s3, granulation: adding 10 parts of sorbitol, 10 parts of calcium hydrogen phosphate dihydrate and 5 parts of microcrystalline cellulose into a high-speed wet mixing granulator, granulating by using a high-efficiency wet granulator, drying by using a fluidized bed, and granulating to obtain dry granules;
s4, total mixing: 2 parts of clove volatile oil, 5 parts of aerosil and 1 part of magnesium stearate are mixed with the granules obtained in the step S3;
s5, tabletting: adjusting the pressure of the tablet press to 30 kilonewtons and the rotating speed of the tablet press to 40 revolutions per minute to prepare tablet candies;
s6, coating a film coat: coating with a high-efficiency coating machine after tabletting to ensure that the surface of the tabletted candy is smooth, flat, fine and solid;
s7, packaging: the packaging material is high-density PE bottle or composite film pressing plate, and is sealed and packaged.
Example 2:
s1, proportioning: preparing raw materials in proportion;
s2, crushing: pre-crushing granular raw materials, and sieving all the raw materials by a 30-mesh sieve to obtain powder;
s3, granulation: adding 10 parts of sorbitol, 10 parts of calcium hydrogen phosphate dihydrate and 10 parts of microcrystalline cellulose into a high-speed wet mixing granulator, granulating by using a high-efficiency wet granulator, drying by using a fluidized bed, and granulating to obtain dry granules;
s4, total mixing: 2 parts of clove volatile oil, 5 parts of aerosil and 1 part of magnesium stearate are mixed with the granules obtained in the step S3;
s5, tabletting: adjusting the pressure of the tablet press to 30 kilonewtons and the rotating speed of the tablet press to 40 revolutions per minute to obtain tablet candy;
s6, coating a film coat: coating with a high-efficiency coating machine after tabletting to ensure that the surface of the tabletted candy is smooth, flat, fine and solid;
s7, packaging: the packaging material is high-density PE bottle or composite film pressing plate, and is sealed and packaged.
Example 3:
s1, proportioning: preparing raw materials in proportion;
s2, crushing: pre-crushing granular raw materials, and sieving all the raw materials with a 30-mesh sieve to obtain powder;
s3, granulation: adding 10 parts of sorbitol, 10 parts of calcium hydrogen phosphate dihydrate and 20 parts of microcrystalline cellulose into a high-speed wet mixing granulator, granulating by using a high-efficiency wet granulator, drying by using a fluidized bed, and granulating to obtain dry granules;
s4, total mixing: 2 parts of clove volatile oil, 5 parts of aerosil and 1 part of magnesium stearate are mixed with the granules obtained in the step S3;
s5, tabletting: adjusting the pressure of the tablet press to 30 kilonewtons and the rotating speed of the tablet press to 40 revolutions per minute to obtain tablet candy;
s6, coating a film coat: coating with a high-efficiency coating machine after tabletting to ensure that the surface of the tabletted candy is smooth, flat, fine and solid;
s7, packaging: the packaging material is high-density PE bottle or composite film pressing plate, and is sealed and packaged.
Example 4:
s1, proportioning: preparing raw materials in proportion;
s2, crushing: pre-crushing granular raw materials, and sieving all the raw materials by a 30-mesh sieve to obtain powder;
s3, granulation: adding 10 parts of sorbitol, 10 parts of calcium hydrogen phosphate dihydrate and 30 parts of microcrystalline cellulose into a high-speed wet mixing granulator, granulating by using a high-efficiency wet granulator, drying by using a fluidized bed, and granulating to obtain dry granules;
s4, total mixing: 2 parts of clove volatile oil, 5 parts of aerosil and 1 part of magnesium stearate are mixed with the granules obtained in the step S3;
s5, tabletting: adjusting the pressure of the tablet press to 30 kilonewtons and the rotating speed of the tablet press to 40 revolutions per minute to prepare tablet candies;
s6, coating a film coat: coating with a high-efficiency coating machine after tabletting to ensure that the surface of the tabletted candy is smooth, fine and solid;
s7, packaging: the packaging material is high-density PE bottle or composite film pressing plate, and is sealed and packaged.
Example 5:
s1, proportioning: preparing raw materials in proportion;
s2, crushing: pre-crushing granular raw materials, and sieving all the raw materials with a 30-mesh sieve to obtain powder;
s3, granulation: adding 10 parts of sorbitol, 10 parts of calcium hydrogen phosphate dihydrate and 40 parts of microcrystalline cellulose into a high-speed wet mixing granulator, granulating by using a high-efficiency wet granulator, drying by using a fluidized bed, and granulating to obtain dry granules;
s4, total mixing: 2 parts of clove volatile oil, 5 parts of aerosil and 1 part of magnesium stearate are mixed with the granules obtained in the step S3;
s5, tabletting: adjusting the pressure of the tablet press to 30 kilonewtons and the rotating speed of the tablet press to 40 revolutions per minute to obtain tablet candy;
s6, coating a film coat: coating with a high-efficiency coating machine after tabletting to ensure that the surface of the tabletted candy is smooth, flat, fine and solid;
s7, packaging: the packaging material is high-density PE bottle or composite film pressing plate, and is sealed and packaged.
Table 2 is sensory evaluation data for the tabletted confectionery products prepared in examples 1 to 6
Example 6:
s1, proportioning: preparing raw materials in proportion;
s2, crushing: pre-crushing granular raw materials, and sieving all the raw materials with a 30-mesh sieve to obtain powder;
s3, granulation: adding 10 parts of sorbitol, 5 parts of calcium hydrogen phosphate dihydrate and 20 parts of microcrystalline cellulose into a high-speed wet mixing granulator, granulating by using a high-efficiency wet granulator, drying by using a fluidized bed, and granulating to obtain dry granules;
s4, total mixing: 2 parts of clove volatile oil, 5 parts of aerosil and 1 part of magnesium stearate are mixed with the granules obtained in the step S3;
s5, tabletting: adjusting the pressure of the tablet press to 30 kilonewtons and the rotating speed of the tablet press to 40 revolutions per minute to obtain tablet candy;
s6, coating a film coat: coating with a high-efficiency coating machine after tabletting to ensure that the surface of the tabletted candy is smooth, flat, fine and solid;
s7, packaging: the packaging material is high-density PE bottle or composite film pressing plate, and is sealed and packaged.
Example 7
S1, proportioning: preparing raw materials in proportion;
s2, crushing: pre-crushing granular raw materials, and sieving all the raw materials with a 30-mesh sieve to obtain powder;
s3, granulation: adding 30 parts of sorbitol, 10 parts of calcium hydrogen phosphate dihydrate and 30 parts of microcrystalline cellulose into a high-speed wet mixing granulator, granulating by using a high-efficiency wet granulator, drying by using a fluidized bed, and granulating to obtain dry granules;
s4, total mixing: mixing 4 parts of clove volatile oil, 16 parts of aerosil and 1 part of magnesium stearate with the granules obtained in the step S3;
s5, tabletting: adjusting the pressure of the tablet press to 30 kilonewtons and the rotating speed of the tablet press to 40 revolutions per minute to obtain tablet candy;
s6, coating a film coat: coating with a high-efficiency coating machine after tabletting to ensure that the surface of the tabletted candy is smooth, fine and solid;
s7, packaging: the packaging material is high-density PE bottle or composite film pressing plate, and is sealed and packaged.
Example 8
S1, proportioning: preparing raw materials in proportion;
s2, crushing: pre-crushing granular raw materials, and sieving all the raw materials with a 30-mesh sieve to obtain powder;
s3, granulation: adding 30 parts of sorbitol, 10 parts of calcium hydrogen phosphate dihydrate and 30 parts of microcrystalline cellulose into a high-speed wet mixing granulator, granulating by using a high-efficiency wet granulator, drying by using a fluidized bed, and granulating to obtain dry granules;
s4, total mixing: mixing 6 parts of clove volatile oil, 14 parts of aerosil and 1 part of magnesium stearate with the granules obtained in the step S3;
s5, tabletting: adjusting the pressure of the tablet press to 30 kilonewtons and the rotating speed of the tablet press to 40 revolutions per minute to obtain tablet candy;
s6, coating a film coat: coating with a high-efficiency coating machine after tabletting to ensure that the surface of the tabletted candy is smooth, flat, fine and solid;
s7, packaging: the packaging material is high-density PE bottle or composite film pressing plate, and is sealed and packaged.
Example 9
S1, proportioning: preparing raw materials in proportion;
s2, crushing: pre-crushing granular raw materials, and sieving all the raw materials with a 30-mesh sieve to obtain powder;
s3, granulation: adding 30 parts of sorbitol, 10 parts of calcium hydrogen phosphate dihydrate and 30 parts of microcrystalline cellulose into a high-speed wet mixing granulator, granulating by using a high-efficiency wet granulator, drying by using a fluidized bed, and granulating to obtain dry granules;
s4, total mixing: mixing 8 parts of clove volatile oil, 12 parts of aerosil and 1 part of magnesium stearate with the granules obtained in the step S3;
s5, tabletting: adjusting the pressure of the tablet press to 30 kilonewtons and the rotating speed of the tablet press to 40 revolutions per minute to obtain tablet candy;
s6, coating a film coat: coating with a high-efficiency coating machine after tabletting to ensure that the surface of the tabletted candy is smooth, flat, fine and solid;
s7, packaging: the packaging material is high-density PE bottle or composite film pressing plate, and is sealed and packaged.
Example 10
S1, proportioning: preparing raw materials in proportion;
s2, crushing: pre-crushing granular raw materials, and sieving all the raw materials with a 30-mesh sieve to obtain powder;
s3, granulation: adding 30 parts of sorbitol, 10 parts of calcium hydrogen phosphate dihydrate and 30 parts of microcrystalline cellulose into a high-speed wet mixing granulator, granulating by using a high-efficiency wet granulator, drying by using a fluidized bed, and granulating to obtain dry granules;
s4, total mixing: mixing 10 parts of clove volatile oil, 10 parts of aerosil and 1 part of magnesium stearate with the granules obtained in the step S3;
s5, tabletting: adjusting the pressure of the tablet press to 30 kilonewtons and the rotating speed of the tablet press to 40 revolutions per minute to obtain tablet candy;
s6, coating a film coat: coating with a high-efficiency coating machine after tabletting to ensure that the surface of the tabletted candy is smooth, flat, fine and solid;
s7, packaging: the packaging material is high-density PE bottle or composite film pressing plate, and is sealed and packaged.
Example 11
S1, proportioning: preparing raw materials in proportion;
s2, crushing: pre-crushing granular raw materials, and sieving all the raw materials with a 30-mesh sieve to obtain powder;
s3, granulation: adding 30 parts of sorbitol, 10 parts of calcium hydrogen phosphate dihydrate and 30 parts of microcrystalline cellulose into a high-speed wet mixing granulator, granulating by using a high-efficiency wet granulator, drying by using a fluidized bed, and granulating to obtain dry granules;
s4, total mixing: mixing 12 parts of clove volatile oil, 8 parts of aerosil and 1 part of magnesium stearate with the granules obtained in the step S3;
s5, tabletting: adjusting the pressure of the tablet press to 30 kilonewtons and the rotating speed of the tablet press to 40 revolutions per minute to obtain tablet candy;
s6, coating a film coat: coating with a high-efficiency coating machine after tabletting to ensure that the surface of the tabletted candy is smooth, flat, fine and solid;
s7, packaging: the packaging material is high-density PE bottle or composite film pressing plate, and is sealed and packaged.
Table 3 shows the hardness and friability of the tabletted confectionery products prepared in example 3 and examples 7 to 11
Example 12
S1, proportioning: preparing raw materials in proportion;
s2, crushing: pre-crushing granular raw materials, and sieving all the raw materials with a 30-mesh sieve to obtain powder;
s3, granulation: adding 30 parts of sorbitol, 25 parts of calcium hydrogen phosphate dihydrate and 30 parts of microcrystalline cellulose into a high-speed wet mixing granulator, granulating by using a high-efficiency wet granulator, drying by using a fluidized bed, and granulating to obtain dry granules;
the specific process steps comprise: s31 dry mixing: adding sorbitol, microcrystalline cellulose and calcium dihydrogen phosphate dihydrate into a high-speed wet mixing granulator, and setting parameters as follows: stirring at 150 revolutions per minute, shearing at 500 revolutions per minute, and dry mixing for 5 minutes;
s32, wet granulation: setting parameters: stirring at 150 revolutions per minute and shearing at 900 revolutions per minute, starting a machine, adding the wetting agent in a spraying manner, continuing to operate for 5 minutes after the addition is finished, and determining a granulation end point according to the properties of the materials;
s33, material suction: setting the parameters of the fluidized bed: 35HZ of air exhaust and heating: setting the discharge parameters of the wet granulator at 50 ℃ and shaking interval time of 300 seconds: stirring for 25 revolutions per minute, performing wet granulation for 800 revolutions per minute, after setting, opening a discharge cabin door of the wet granulator and a feeding switch of the fluidized bed, and sucking materials in the wet granulator into the fluidized bed through a connecting pipe for boiling;
s34, drying: firstly, setting exhaust air 28HZ, and heating: shaking the bag at 50 ℃ for 90 seconds at an interval time, maintaining for 10 minutes, and then setting: exhausting air for 20HZ, and heating: shaking the bags at 50 ℃ for 90 seconds at intervals, keeping for 20 minutes, stopping the machine, sampling to measure moisture, controlling the moisture to be 5 percent, stopping the machine to discharge after drying is finished, and preparing to granulate;
s35, finishing, namely connecting a fluidized bed bin with a matched lifting turnover machine, performing dry finishing after lifting turnover to obtain finished dry particles, and packaging and storing the dry particles in double-layer PE bags or transferring a mixing bin by a material mixing machine to directly receive materials;
s4, total mixing: mixing 4 parts of clove volatile oil, 16 parts of aerosil and 0.5 part of magnesium stearate with the total granules obtained in the step S3, starting a mixer, and setting: the rotating speed is 10 r/min, the mixing time is 5min, the machine is stopped, magnesium stearate with the amount of the prescription is added, the mixing is continued for 3 min, and the machine is stopped for blanking after the mixing is finished.
S5, tabletting: adjusting the pressure of the tablet press to 30 kilonewtons and the rotating speed of the tablet press to 40 revolutions per minute to prepare tablet candies;
s6, coating a film coat: placing 6.14kg of purified water in a slurry preparation container, starting stirring to keep the solution in a vortex shape, slowly adding 1kg of brown coating powder, and continuously stirring for 45 minutes to obtain a coating solution;
putting the tablet core into a coating pan, intermittently rolling the pan body at the lowest speed, and preheating to the temperature of 37-40 ℃ of the tablet core.
Coating process control data: air inlet temperature: 70 +/-5 ℃; the atomization pressure is 0.4 +/-0.1 MPa; temperature of the slice bed: 40 ℃; after coating, closing the spray gun, reducing the rotating speed, and drying the tablets for 10 minutes; confirming that the sheet is completely dry, closing the air inlet heating system, and intermittently rolling the pan body until the temperature of the sheet bed reaches the room temperature; the coated tablets were transferred to a defined container.
S7, packaging: the packaging material is high-density PE bottle or composite film pressing plate, and is sealed and packaged.
Example 13
S1, proportioning: preparing raw materials in proportion;
s2, crushing: pre-crushing granular raw materials, and sieving all the raw materials with a 30-mesh sieve to obtain powder;
s3, granulation: adding 30 parts of sorbitol, 25 parts of calcium hydrogen phosphate dihydrate and 30 parts of microcrystalline cellulose into a high-speed wet mixing granulator, granulating by using a high-efficiency wet granulator, drying by using a fluidized bed, and granulating to obtain dry granules;
the specific process steps comprise: s31 dry mixing: adding sorbitol, microcrystalline cellulose and calcium dihydrogen phosphate dihydrate into a high-speed wet mixing granulator, and setting parameters as follows: stirring at 150 revolutions per minute, shearing at 500 revolutions per minute, and dry mixing for 5 minutes;
s32, wet granulation: setting parameters: stirring at 150 revolutions per minute and shearing at 900 revolutions per minute, starting a machine, adding the wetting agent in a spraying manner, continuing to operate for 5 minutes after the addition is finished, and determining a granulation end point according to the properties of the materials;
s33, material suction: setting the parameters of the fluidized bed: 35HZ of air exhaust and heating: setting the discharge parameters of the wet granulator at 50 ℃ and shaking interval time of 300 seconds: stirring for 25 revolutions per minute, finishing wet granulation for 800 revolutions per minute, starting a discharge cabin door of the wet granulator and a feeding switch of the fluidized bed after setting is finished, and sucking materials in the wet granulator into the fluidized bed through a connecting pipe for boiling;
s34, drying: firstly, setting exhaust air 28HZ, and heating: shaking the bag at 50 ℃ for 90 seconds at an interval time, maintaining for 10 minutes, and then setting: exhausting air for 20HZ, heating: shaking the bags at 50 ℃ for 90 seconds at intervals, keeping for 20 minutes, stopping the machine, sampling to measure moisture, controlling the moisture to be 5 percent, stopping the machine to discharge after drying is finished, and preparing to granulate;
s35, finishing, namely connecting a fluidized bed bin with a matched lifting turnover machine, performing dry finishing after lifting turnover to obtain finished dry particles, and packaging and storing the dry particles in double-layer PE bags or directly receiving materials in a material mixing machine transferring and mixing bin;
s4, total mixing: and (3) mixing 4 parts of clove volatile oil, 16 parts of aerosil and 2.5 parts of magnesium stearate with the total granules obtained in the step (S3), starting a mixer, and setting: the rotating speed is 10 r/min, the mixing time is 5min, the machine is stopped, magnesium stearate with the amount of the prescription is added, the mixing is continued for 3 min, and the machine is stopped for blanking after the mixing is finished.
S5, tabletting: adjusting the pressure of the tablet press to 30 kilonewtons and the rotating speed of the tablet press to 40 revolutions per minute to obtain tablet candy;
s6, coating a film coat: placing 6.14kg of purified water in a slurry preparation container, starting stirring to keep the solution in a vortex shape, slowly adding 1kg of brown coating powder, and continuously stirring for 45 minutes to obtain a coating solution;
putting the tablet core into a coating pan, intermittently rolling the pan body at the lowest speed, and preheating to the temperature of 37-40 ℃ of the tablet core.
Coating process control data: air inlet temperature: 70 +/-5 ℃; the atomization pressure is 0.4 +/-0.1 MPa; temperature of the slice bed: 40 ℃; after coating, closing the spray gun, reducing the rotating speed, and drying the tablets for 10 minutes; confirming that the slices are completely dried, closing the air inlet heating system, and intermittently rolling the pot body until the temperature of the slice bed reaches the room temperature; the coated tablets were transferred to a defined container.
S7, packaging: the packaging material is high-density PE bottle or composite film pressing plate, and is sealed and packaged.
Results of index measurement of products prepared in example 12 and example 13
Although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments described above, or equivalents may be substituted for elements thereof. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (8)
1. The tabletting candy containing clove volatile oil is characterized by comprising the following components in parts by weight:
2. a process for preparing a tabletted confectionery product according to claim 1, comprising the steps of:
s1, proportioning: preparing raw materials in proportion;
s2, crushing: pre-crushing granular raw materials, and sieving all the raw materials with a 30-mesh sieve to obtain powder;
s3, granulation: adding sorbitol, calcium hydrogen phosphate dihydrate and microcrystalline cellulose into a high-speed wet mixing granulator, granulating by using a high-efficiency wet granulator, drying by using a fluidized bed, and granulating to obtain dry granules;
s4, total mixing: mixing the clove volatile oil, the aerosil and the magnesium stearate with the granules obtained in the step S3;
s5, tabletting: adjusting the pressure of the tablet press to 30 kilonewtons and the rotating speed of the tablet press to 40 revolutions per minute to obtain tablet candy;
s6, coating a film coat: coating with a high-efficiency coating machine after tabletting to ensure that the surface of the tabletted candy is smooth, flat, fine and solid;
s7, packaging: the packaging material is high-density PE bottle or composite film pressing plate, and is sealed and packaged.
3. The preparation process according to claim 2, wherein the granulation comprises the following specific steps:
s31 dry mixing: adding sorbitol, microcrystalline cellulose and calcium dihydrogen phosphate dihydrate into a high-speed wet mixing granulator, and setting parameters as follows: stirring at 150 revolutions per minute, shearing at 500 revolutions per minute, and dry mixing for 5 minutes;
s32, wet granulation: setting parameters: stirring at 150 revolutions per minute and shearing at 900 revolutions per minute, starting a machine, adding the wetting agent in a spraying manner, continuing to operate for 5 minutes after the addition is finished, and determining a granulation end point according to the properties of the materials;
s33, material suction: setting the parameters of the fluidized bed: 35HZ of air exhaust and heating: setting the discharge parameters of the wet granulator at 50 ℃ and shaking interval time of 300 seconds: stirring for 25 revolutions per minute, performing wet granulation for 800 revolutions per minute, after setting, opening a discharge cabin door of the wet granulator and a feeding switch of the fluidized bed, and sucking materials in the wet granulator into the fluidized bed through a connecting pipe for boiling;
s34, drying: firstly, setting exhaust air 28HZ, and heating: shaking the bag at 50 ℃ for 90 seconds at an interval time, maintaining for 10 minutes, and then setting: exhausting air for 20HZ, heating: shaking the bags at 50 ℃ for 90 seconds at intervals, keeping for 20 minutes, stopping the machine, sampling to measure moisture, controlling the moisture to be 5 percent, stopping the machine to discharge after drying is finished, and preparing to granulate;
s35, finishing, namely connecting a fluidized bed bin with a matched lifting turnover machine, performing dry finishing after lifting turnover to obtain finished dry particles, and packaging and storing the dry particles in double-layer PE bags or directly receiving the materials in a material mixing machine transferring and mixing bin.
4. The process according to claim 3, wherein the ratio of wetting agent: a 10wt% ethanol solution, in a total amount of 270g, corresponding to 1000 tablets of tabletted candy.
5. The preparation process according to claim 4, wherein the whole dry granules, the clove volatile oil and the aerosil are sequentially added into a main mixer, and the mixer is started to set the following components: the rotating speed is 10 r/min, the mixing time is 5min, the machine is stopped, magnesium stearate with the amount of the prescription is added, the mixing is continued for 3 min, and the machine is stopped for blanking after the mixing is finished.
6. The process according to claim 2, wherein the tabletting comprises the steps of: adjusting the pressure of the tablet press to 5-40 kilonewtons, the rotating speed of the tablet press to 10-80 rpm, and checking the average tablet weight once every 15 min; check every 30min for a single tablet to be a heavy one, taking 10 tablets each time.
7. The preparation process according to claim 2, wherein the coating comprises the following specific steps:
placing 6.14kg of purified water in a slurry preparation container, starting stirring to keep the solution in a vortex shape, slowly adding 1kg of brown coating powder, and continuously stirring for 45 minutes to obtain a coating solution;
putting the tablet core into a coating pan, intermittently rolling the pan body at the lowest speed, and preheating to the temperature of 37-40 ℃ of the tablet core.
8. The process of claim 7, wherein the coating process control data: air inlet temperature: 70 +/-5 ℃; the atomization pressure is 0.4 +/-0.1 MPa; temperature of the slice bed: 40 ℃; after coating, closing the spray gun, reducing the rotating speed, and drying the tablets for 10 minutes; confirming that the slices are completely dried, closing the air inlet heating system, and intermittently rolling the pot body until the temperature of the slice bed reaches the room temperature; the coated tablets were transferred to a defined container.
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0452262A2 (en) * | 1990-04-09 | 1991-10-16 | Pfizer Inc. | Reduced calorie pressed tablet with improved mouthfeel |
| CN105994908A (en) * | 2016-06-06 | 2016-10-12 | 广东工业大学 | Tableting sugar and preparation method and application thereof |
| CN110638780A (en) * | 2019-09-11 | 2020-01-03 | 华益药业科技(安徽)有限公司 | Nefopam hydrochloride tablet and preparation method thereof |
| CN112790268A (en) * | 2021-01-04 | 2021-05-14 | 安徽尚美轩生物技术有限公司 | Red pomegranate tablet candy and production process thereof |
| CN114586881A (en) * | 2021-04-21 | 2022-06-07 | 长春纳典生物技术有限公司 | Grape seed extract tablet candy and preparation method thereof |
-
2022
- 2022-11-29 CN CN202211509412.9A patent/CN115812823A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0452262A2 (en) * | 1990-04-09 | 1991-10-16 | Pfizer Inc. | Reduced calorie pressed tablet with improved mouthfeel |
| CN105994908A (en) * | 2016-06-06 | 2016-10-12 | 广东工业大学 | Tableting sugar and preparation method and application thereof |
| CN110638780A (en) * | 2019-09-11 | 2020-01-03 | 华益药业科技(安徽)有限公司 | Nefopam hydrochloride tablet and preparation method thereof |
| CN112790268A (en) * | 2021-01-04 | 2021-05-14 | 安徽尚美轩生物技术有限公司 | Red pomegranate tablet candy and production process thereof |
| CN114586881A (en) * | 2021-04-21 | 2022-06-07 | 长春纳典生物技术有限公司 | Grape seed extract tablet candy and preparation method thereof |
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