CN115777931A - Dietary supplement for coordinating intestines and stomach and preparation method and application thereof - Google Patents
Dietary supplement for coordinating intestines and stomach and preparation method and application thereof Download PDFInfo
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- CN115777931A CN115777931A CN202211541499.8A CN202211541499A CN115777931A CN 115777931 A CN115777931 A CN 115777931A CN 202211541499 A CN202211541499 A CN 202211541499A CN 115777931 A CN115777931 A CN 115777931A
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Abstract
The invention discloses a dietary supplement for coordinating intestines and stomach, a preparation method and application thereof, belonging to the technical field of nutriology; the dietary supplement comprises the following preparation raw materials: chinese yam, rice thin tablets, corn oligopeptide powder, soybean peptide powder, konjak, white sesame, hericium erinaceus, edible bird's nest, poria cocos, lotus seeds, walnuts, bifidobacterium longum, lactobacillus plantarum, lactobacillus reuteri, calcium carbonate, zinc gluconate, ferrous gluconate and xylitol. The dietary supplement for regulating the intestines and the stomach provided by the invention can improve the balance of gastrointestinal microbial flora and form sustainable healthy microecology so as to effectively inhibit the growth of gastrointestinal odor-producing bacteria and finally achieve the purpose of maintaining the health of the gastrointestinal tract.
Description
Technical Field
The invention belongs to the technical field of nutriology, and particularly relates to a dietary supplement for coordinating intestines and stomach, and a preparation method and application thereof.
Background
A dietary supplement is a product intended to supplement the diet and may contain one or more of the following dietary ingredients, vitamins, minerals, herbs or other plants, amino acids, food ingredients to increase total daily intake to supplement the diet, or a concentrate, metabolite, ingredient, extract or combination thereof.
The application of the current dietary supplement in health food is mostly single variety application, for example, patent publication No. CN108552446A discloses a preparation method of passion fruit peel slurry and a passion fruit peel dietary fiber beverage, and the passion fruit peel dietary fiber beverage is prepared by mixing the prepared passion fruit peel slurry with edible dressing. Dietary fiber of a single component is not significantly effective in improving gastrointestinal sub-health status.
Accordingly, the present invention provides a dietary supplement for gastrointestinal conditioning that addresses at least one of the problems and deficiencies set forth in the background above.
Disclosure of Invention
It is an object of the present invention to provide a dietary supplement for gastrointestinal conditioning that addresses at least one of the problems and deficiencies set forth in the background above.
The invention also provides a preparation method of the dietary supplement for coordinating intestines and stomach.
The invention also provides application of the dietary supplement for regulating intestines and stomach.
Specifically, in a first aspect, the invention provides a dietary supplement for regulating intestines and stomach, which comprises the following preparation raw materials: chinese yam, rice flakes, corn oligopeptide powder, soybean peptide powder, konjak, white sesame, hericium erinaceus, edible bird's nest, poria cocos, lotus seeds, walnuts, bifidobacterium longum, lactobacillus plantarum, lactobacillus reuteri, calcium carbonate, zinc gluconate, ferrous gluconate and xylitol.
According to one technical scheme of the dietary supplement, the dietary supplement has at least the following beneficial effects:
the Chinese yam contains various trace elements, abundant vitamins and mineral substances, particularly has high potassium content and relatively low heat; the Chinese yam contains diastase which can decompose starch, has the function of promoting digestion, can remove uncomfortable symptoms, is beneficial to improving the digestion and absorption functions of the spleen and the stomach, and is a good product for both medicine and food for tonifying the spleen and the stomach; the rhizoma Dioscoreae contains mucin, cellulase, saponin, free amino acids, polyphenol oxidase, etc., and is rich in nutrition and has nourishing effect.
The rice flakes are a kind of sugar made by the action of saccharifying enzyme in malt on starch in broken rice. It is light yellow, viscous and transparent liquid. The main components are maltose, glucose and dextrin. Sweet, soft and tasty. In traditional Chinese medicine, the traditional Chinese medicine is used as a medicine for relieving middle-jiao deficiency, tonifying deficiency and moistening lung, has mild nature, and is mainly used for treating symptoms such as middle-jiao deficiency abdominal pain, lung dryness cough and the like.
The corn oligopeptide powder has various biological activities, such as oxidation resistance, hypertension resistance, immunity enhancement, fatigue resistance, liver protection and the like.
The soybean peptide powder contains various bioactive peptides, and has various physiological activities including resisting oxidation, lowering blood pressure, lowering cholesterol, reducing blood lipid, relieving fatigue, and enhancing immunity.
The konjak contains rich carbohydrate, low calorie, high protein content, rich trace elements, vitamin A, vitamin B and the like, particularly rich glucomannan, and has the effects of losing weight, reducing blood pressure, reducing blood sugar, expelling toxin, relaxing bowels, preventing cancer, supplementing calcium and the like.
White sesame is sweet in taste and neutral in nature, and enters liver, kidney, lung and spleen meridians; has effects in replenishing blood, improving eyesight, expelling pathogenic wind, moisturizing intestine, promoting salivation, promoting lactation, tonifying liver, nourishing hair, strengthening body constitution, and resisting aging.
The hericium erinaceus contains hericium erinaceus polysaccharide, and the hericium erinaceus polysaccharide has a good pharmacological effect on various digestive system diseases such as gastritis, colitis, dyspepsia, gastric ulcer, duodenal ulcer and the like; thereby playing a good role in coordinating intestines and stomach.
The edible bird's nest has rich amino acid types and is rich in phenylalanine, valine, leucine, tyrosine, arginine and the like.
The poria cocos contains pachymaran, and the pachymaran has a promoting effect on intestinal sIgA secretion and can induce intestinal immune response, so that the effect of regulating immunity is achieved.
The lotus seed contains lotus seed polysaccharide which has the function of resisting ulcer, thereby playing a certain role in maintaining intestines and stomach.
The walnut has the function of supplementing protein, vitamins and minerals, thereby improving the immunity.
The bifidobacterium longum, the lactobacillus plantarum and the lactobacillus reuteri synergistically reduce the number of helicobacter pylori in the gastric mucosa, so that the intestinal microecology is adjusted, and the conditions of gastric mucosa inflammation and the like are improved; the bacteria can be planted in the oral cavity and the gastrointestinal tract, once the bacteria are adhered and planted, a protective layer is formed on the surface of the gastrointestinal tract to prevent the adhesion of pathogenic bacteria, and the effect is more durable. Lactobacillus reuteri may also reduce gastritis.
Xylitol has a promoting effect on the beneficial bacteria effect of the probiotics and improves the growth inhibition effect of the probiotics on pathogenic bacteria.
The calcium carbonate, zinc gluconate and ferrous gluconate have the function of a nutritional supplement, thereby supplementing the required trace elements.
According to some embodiments of the invention, the gastrointestinal dietary supplement comprises the following preparation raw materials in parts by weight:
5 to 8 parts of yam, 12 to 15 parts of rice flake, 6 to 9 parts of corn oligopeptide powder, 22 to 25 parts of soybean peptide powder, 8 to 12 parts of konjak, 2 to 5 parts of white sesame, 18 to 20 parts of hericium erinaceus, 24 to 26 parts of edible bird's nest, 6 to 9 parts of tuckahoe, 16 to 18 parts of lotus seed, 22 to 25 parts of walnut, 2 to 5 parts of bifidobacterium longum, 3 to 6 parts of lactobacillus plantarum, 3 to 5 parts of lactobacillus reuteri, 4 to 7 parts of calcium carbonate, 2 to 5 parts of zinc gluconate, 7 to 10 parts of ferrous gluconate and 3 to 5 parts of xylitol.
In a second aspect, the invention provides a preparation method of the dietary supplement for regulating intestines and stomach, which comprises the following steps:
s1, mixing Chinese yam, konjak, white sesame, hericium erinaceus, poria cocos, lotus seeds and walnuts to obtain a mixture;
adding the mixture into water, performing ultrasonic-assisted complex enzyme extraction, performing solid-liquid separation, and collecting liquid phase to obtain extractive solution;
s2, intercepting the extracting solution prepared in the step S1 by adopting an ultrafiltration membrane to prepare intercepted solution;
s3, freeze-drying the trapped fluid to obtain an extract;
s4, mixing the extract, the corn oligopeptide powder, the soybean peptide powder, the edible bird' S nest, the bifidobacterium longum, the lactobacillus plantarum, the lactobacillus reuteri, the calcium carbonate, the zinc gluconate, the ferrous gluconate and the xylitol;
the cut-off molecular weight of the ultrafiltration membrane is more than 8 kD.
According to one of the technical schemes of the preparation method, the invention at least has the following beneficial effects:
according to the preparation method, the plant raw materials are subjected to ultrasonic extraction by adopting the complex enzyme, and the cell walls of the plants are treated by utilizing the complex enzyme, so that the effective release of the components in the plants is improved, the content of the effective components in the finally prepared dietary supplement is improved, and the gastrointestinal conditioning effect of the dietary supplement is further promoted.
In the invention, the extracting solution is intercepted by adopting an ultrafiltration membrane, so that the further purification and screening of each component in the extracting solution are realized, the content of effective components in the final extract is further improved, and the gastrointestinal conditioning effect of the dietary supplement is further improved.
According to some embodiments of the invention, the complex enzyme consists of cellulase and pectinase.
According to some embodiments of the invention, the mass ratio of the cellulase to the pectinase is 1.
According to some embodiments of the invention, the mass ratio of the complex enzyme to the mixture is 0.2-0.3.
The cellulase and the pectinase are matched for use, so that the decomposition effect of the plant cell wall is further improved, and the effective extraction of effective components in the plant is promoted.
According to some embodiments of the invention, the power of the ultrasound is between 100W and 200W.
According to some embodiments of the invention, the temperature of the extraction is between 40 ℃ and 60 ℃.
By controlling the extraction temperature, the activity of the enzyme is controlled, and the extraction effect of the complex enzyme is favorably improved.
According to some embodiments of the invention, the time of extraction is 60min to 120min.
According to some embodiments of the invention, the post-mixing pulverization of step S1.
According to some embodiments of the invention, the mesh size of the mixture is 60 to 80 mesh.
According to some embodiments of the invention, the ultrafiltration membrane has a molecular weight cut-off in the range of 8kD to 12kD.
In a third aspect, the invention provides an application of the dietary supplement for regulating intestines and stomach in preparing health care products.
Detailed Description
The concept and technical effects of the present invention will be clearly and completely described below in conjunction with the embodiments to fully understand the objects, features and effects of the present invention. It is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments, and those skilled in the art can obtain other embodiments without inventive effort based on the embodiments of the present invention, and all embodiments are within the protection scope of the present invention.
In the description of the present invention, reference to the description of "one embodiment", "some embodiments", "illustrative embodiments", "examples", "specific examples", or "some examples", etc., means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the present invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The examples, in which specific conditions are not specified, were carried out according to conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are conventional products which are not indicated by manufacturers and are commercially available.
Cellulase: xiasang FFG-0666.
And (3) pectinase: xiasang FFY-0654.
Yam powder: purchased from Jiangsu Runhui food Co.
Rice thin slices: purchased from Jiangxi cereal-derived food Co., ltd.
Corn oligopeptide powder: purchased from sienna green peptide biotechnology limited.
Soybean peptide powder: purchased from peptidomimetics technologies (Xiamen) Inc.
Konjak flour: purchased from Jiangsu Runhui food Co.
White sesame seeds: purchased from Shenyang Hongxing food Co.
Hericium erinaceus powder: purchased from Jiangsu Runhui food Co.
Eating oat: purchased from Jiangsu Runhui food Co.
Tuckahoe, poria cocos: purchased from bozhou renyi chinese medicinal materials sales limited.
Lotus seed: purchased from Jiangsu Runhui food Co.
Walnut: purchased from Jiangsu Runhui food Co.
Bifidobacterium longum: BNCC186627 of the institute of biotechnology, north nai, institute of biotechnology.
The lactobacillus plantarum: BNCC336421 from institute of biotechnology, north nai institute of innovation.
Lactobacillus reuteri: BNCC254476 from institute of biotechnology, north nai institute of innovation.
Example 1
The embodiment is a dietary supplement for coordinating intestines and stomach, which consists of the following preparation raw materials in parts by weight:
8 parts of yam flour, 15 parts of rice flakes, 9 parts of corn oligopeptide powder, 25 parts of soybean peptide powder, 10 parts of konjac powder, 4 parts of white sesame, 20 parts of hericium erinaceus powder, 25 parts of edible bird's nest, 9 parts of poria cocos, 17 parts of lotus seed, 22 parts of walnut, 5 parts of bifidobacterium longum, 6 parts of lactobacillus plantarum, 5 parts of lactobacillus reuteri, 4 parts of calcium carbonate, 2 parts of zinc gluconate, 7 parts of ferrous gluconate and 5 parts of xylitol;
the preparation method of the dietary supplement for regulating intestines and stomach in the embodiment comprises the following steps:
s1, mixing Chinese yam, konjak, white sesame, hericium erinaceus, poria cocos, lotus seeds and walnuts, and then crushing to 80 meshes to obtain a mixture;
adding the mixture into water (the mass-volume ratio of the mixture to the water is 1g 100mL), ultrasonically assisting complex enzyme extraction (the ultrasonic power is 100W, the complex enzyme consists of cellulase and pectinase, the ultrasonic time is 120min, the extraction temperature is 45 ℃), performing enzyme deactivation treatment (the enzyme deactivation temperature is 100 ℃, the enzyme deactivation time is 6 min) after the extraction is finished, performing solid-liquid separation, and collecting a liquid phase to obtain an extracting solution;
s2, intercepting the extracting solution prepared in the step S1 by adopting an ultrafiltration membrane (the intercepted molecular weight is 8 kD-12 kD) to prepare intercepted solution;
s3, freeze-drying the trapped fluid (the freeze-drying temperature is-40 ℃) to obtain an extract;
s4, mixing the extract, the corn oligopeptide powder, the soybean peptide powder, the edible bird' S nest, the bifidobacterium longum, the lactobacillus plantarum, the lactobacillus reuteri, the calcium carbonate, the zinc gluconate, the ferrous gluconate and the xylitol.
Example 2
The embodiment is a dietary supplement for coordinating intestines and stomach, which consists of the following preparation raw materials in parts by weight:
5 parts of yam flour, 15 parts of rice flakes, 6 parts of corn oligopeptide powder, 22 parts of soybean peptide powder, 8 parts of konjac powder, 5 parts of white sesame, 18 parts of hericium erinaceus powder, 24 parts of edible bird's nest, 6 parts of poria cocos, 16 parts of lotus seed, 25 parts of walnut, 5 parts of bifidobacterium longum, 6 parts of lactobacillus plantarum, 5 parts of lactobacillus reuteri, 4 parts of calcium carbonate, 2 parts of zinc gluconate, 7 parts of ferrous gluconate and 3 parts of xylitol.
The dietary supplement for regulating the intestines and stomach in this example was prepared in the same manner as in example 1.
Example 3
The present example is a dietary supplement for regulating the intestines and stomach, and the difference from the example 1 is that: a method for preparing dietary supplement for regulating intestine and stomach is provided.
The preparation method of the dietary supplement for regulating intestines and stomach in the embodiment comprises the following steps:
s1, mixing Chinese yam, konjak, white sesame, hericium erinaceus, poria cocos, lotus seeds and walnuts, and then crushing to 80 meshes to obtain a mixture;
adding the mixture into water (the mass-volume ratio of the mixture to the water is 1g 100mL), ultrasonically assisting complex enzyme extraction (the ultrasonic power is 100W, the complex enzyme consists of cellulase and pectinase, the ultrasonic time is 120min, the extraction temperature is 45 ℃), performing enzyme deactivation treatment (the enzyme deactivation temperature is 100 ℃, the enzyme deactivation time is 6 min) after the extraction is finished, performing solid-liquid separation, and collecting a liquid phase to obtain an extracting solution;
s2, freeze-drying the extracting solution (the freeze-drying temperature is-40 ℃) to obtain an extract;
s4, mixing the extract, the corn oligopeptide powder, the soybean peptide powder, the edible bird' S nest, the bifidobacterium longum, the lactobacillus plantarum, the lactobacillus reuteri, the calcium carbonate, the zinc gluconate, the ferrous gluconate and the xylitol.
Example 4
The present example is a dietary supplement for regulating the intestines and stomach, and the difference from the example 1 is that: a method for preparing dietary supplement for regulating intestine and stomach is provided.
The preparation method of the dietary supplement for regulating the intestines and stomach in the embodiment comprises the following steps:
s1, mixing Chinese yam, konjak, white sesame, hericium erinaceus, poria cocos, lotus seeds and walnuts, and then crushing to 80 meshes to obtain a mixture;
adding the mixture into water (the mass-volume ratio of the mixture to the water is 1g 100mL), performing ultrasonic-assisted extraction (the ultrasonic power is 100W, the ultrasonic time is 120min, and the extraction temperature is 45 ℃), performing enzyme deactivation treatment (the enzyme deactivation temperature is 100 ℃ and the enzyme deactivation time is 6 min) after the extraction is finished, performing solid-liquid separation, and collecting a liquid phase to obtain an extracting solution;
s2, intercepting the extracting solution prepared in the step S1 by adopting an ultrafiltration membrane (the intercepted molecular weight is 8 kD-12 kD) to prepare intercepted solution;
s3, freeze-drying the trapped fluid (the freeze-drying temperature is-40 ℃) to obtain an extract;
s4, mixing the extract, the corn oligopeptide powder, the soybean peptide powder, the edible bird' S nest, the bifidobacterium longum, the lactobacillus plantarum, the lactobacillus reuteri, the calcium carbonate, the zinc gluconate, the ferrous gluconate and the xylitol.
Comparative example 1
The comparative example is a dietary supplement for coordinating intestines and stomach, which consists of the following preparation raw materials in parts by weight:
5 parts of yam powder, 15 parts of rice-flour noodle slices, 6 parts of corn oligopeptide powder, 22 parts of soybean peptide powder, 8 parts of konjaku flour, 5 parts of white sesame, 18 parts of hericium erinaceus powder, 24 parts of edible bird's nest, 6 parts of poria cocos, 16 parts of lotus seeds, 25 parts of walnuts, 4 parts of calcium carbonate, 2 parts of zinc gluconate, 7 parts of ferrous gluconate and 3 parts of xylitol.
The preparation method of the dietary supplement for regulating intestines and stomach in the comparative example is the same as that of the example 1.
Comparative example 2
The comparative example is a dietary supplement for coordinating intestines and stomach, which consists of the following preparation raw materials in parts by weight:
15 parts of rice thin slice, 6 parts of corn oligopeptide powder, 22 parts of soybean peptide powder, 8 parts of konjac powder, 5 parts of white sesame, 18 parts of hericium erinaceus powder, 24 parts of edible bird's nest, 6 parts of poria cocos, 16 parts of lotus seed, 25 parts of walnut, 5 parts of bifidobacterium longum, 6 parts of lactobacillus plantarum, 5 parts of lactobacillus reuteri, 4 parts of calcium carbonate, 2 parts of zinc gluconate, 7 parts of ferrous gluconate and 3 parts of xylitol.
The gastrointestinal dietary supplement of this comparative example was prepared in the same manner as in example 1.
Comparative example 3
The comparative example is a dietary supplement for coordinating intestines and stomach, and the dietary supplement comprises the following preparation raw materials in parts by weight:
15 parts of rice thin slice, 6 parts of corn oligopeptide powder, 22 parts of soybean peptide powder, 8 parts of konjac flour, 5 parts of white sesame, 24 parts of edible bird's nest, 6 parts of poria cocos, 16 parts of lotus seed, 25 parts of walnut, 5 parts of bifidobacterium longum, 6 parts of lactobacillus plantarum, 5 parts of lactobacillus reuteri, 4 parts of calcium carbonate, 2 parts of zinc gluconate, 7 parts of ferrous gluconate and 3 parts of xylitol.
The gastrointestinal dietary supplement of this comparative example was prepared in the same manner as in example 1.
Test examples
The test process comprises the following steps: 160 HP negative patients (80 males, 80 females; mean age 40 + -10 years, between 30 and 50 years) were selected and were all voluntarily enrolled in the trial and did not take any antibiotics for the three month period prior to enrollment.
The test method comprises the following steps: the test subjects were randomly divided into eight groups of 10 persons each, and the number of male and female persons in the two groups was equal, and the test groups were 1 to 7 and the control group, respectively, and the test period was two weeks.
Test group 1: example 1 corresponds to a dietary supplement.
Test group 2: example 2 corresponding dietary supplement.
Test group 3: example 3 corresponding dietary supplement.
Test group 4: example 4 corresponding dietary supplement.
Test group 5: comparative example 1 corresponds to a dietary supplement.
Test group 6: comparative example 2 corresponds to a dietary supplement.
Test group 7: comparative example 3 corresponds to a dietary supplement.
Control group: standard triple combination therapy against helicobacter pylori was performed daily (omeprazole + amoxicillin + clarithromycin, treatment period of two weeks).
Test groups 1-7 were taking 1 gram of the dietary supplement provided by the present invention at the same time after each of the Chinese and evening meals.
After two weeks, the subjects were subjected to a carbon 14 breath test to evaluate the therapeutic effect of helicobacter pylori. Specific results are shown in table 1 below.
TABLE 1 comparison of the results of C14 breath test of subjects before and after the experiments of examples 1 to 4 and comparative examples 1 to 3
Carbon 14 breath test: the result value is less than 100, the result value is HP negative, and the result value is more than or equal to 100, the result value is HP positive.
In conclusion, the dietary supplement for regulating intestines and stomach provided by the invention can improve the balance of gastrointestinal microbial flora and form sustainable healthy microecology so as to effectively inhibit the growth of odor-producing bacteria in the gastrointestinal tract and finally achieve the aim of maintaining the health of the gastrointestinal tract. And simultaneously, the composition can effectively inhibit helicobacter pylori infection and regulate the immune function of an organism, thereby improving the micro-ecological environment of the gastrointestinal tract.
The above embodiments are provided to further explain the objects, technical solutions and advantages of the present invention in detail, it should be understood that the above embodiments are only examples of the present invention and are not intended to limit the present invention, and any modifications, equivalents, improvements and the like made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (10)
1. The dietary supplement for coordinating intestines and stomach is characterized by comprising the following preparation raw materials: chinese yam, rice thin tablets, corn oligopeptide powder, soybean peptide powder, konjak, white sesame, hericium erinaceus, edible bird's nest, poria cocos, lotus seeds, walnuts, bifidobacterium longum, lactobacillus plantarum, lactobacillus reuteri, calcium carbonate, zinc gluconate, ferrous gluconate and xylitol.
2. The gastrointestinal conditioning dietary supplement of claim 1, comprising the following preparation raw materials in parts by weight:
5 to 8 parts of yam, 12 to 15 parts of rice flake, 6 to 9 parts of corn oligopeptide powder, 22 to 25 parts of soybean peptide powder, 8 to 12 parts of konjak, 2 to 5 parts of white sesame, 18 to 20 parts of hericium erinaceus, 24 to 26 parts of edible bird's nest, 6 to 9 parts of tuckahoe, 16 to 18 parts of lotus seed, 22 to 25 parts of walnut, 2 to 5 parts of bifidobacterium longum, 3 to 6 parts of lactobacillus plantarum, 3 to 5 parts of lactobacillus reuteri, 4 to 7 parts of calcium carbonate, 2 to 5 parts of zinc gluconate, 7 to 10 parts of ferrous gluconate and 3 to 5 parts of xylitol.
3. A method of preparing the gastrointestinal-conditioning dietary supplement of claim 1 or 2, comprising the steps of:
s1, mixing Chinese yam, konjak, white sesame, hericium erinaceus, poria cocos, lotus seeds and walnuts to obtain a mixture;
adding the mixture into water, performing ultrasonic-assisted complex enzyme extraction, performing solid-liquid separation, and collecting liquid phase to obtain extractive solution;
s2, intercepting the extracting solution prepared in the step S1 by adopting an ultrafiltration membrane to prepare intercepted solution;
s3, freeze-drying the trapped fluid to obtain an extract;
s4, mixing the extract, the corn oligopeptide powder, the soybean peptide powder, the edible bird' S nest, the bifidobacterium longum, the lactobacillus plantarum, the lactobacillus reuteri, the calcium carbonate, the zinc gluconate, the ferrous gluconate and the xylitol;
the cut-off molecular weight of the ultrafiltration membrane is more than 8 kD.
4. The method according to claim 3, wherein the complex enzyme consists of cellulase and pectinase.
5. The method according to claim 4, wherein the mass ratio of the cellulase to the pectinase is 1.
6. The method according to claim 3, wherein the mass ratio of the complex enzyme to the mixture is 0.2-0.3.
7. The method of claim 3, wherein the power of the ultrasound is 100W to 200W.
8. The method according to claim 3, wherein the temperature of the extraction is 40 ℃ to 60 ℃.
9. The method of claim 3, wherein the ultrafiltration membrane has a molecular weight cut-off in the range of 8kD to 10kD.
10. Use of the dietary supplement for regulating the gastrointestinal tract of claim 1 or 2 in the preparation of a health product.
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| CN117859893A (en) * | 2024-02-29 | 2024-04-12 | 杭州海王生物工程有限公司 | Healthy dietary supplement and preparation method thereof |
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| CN115074298A (en) * | 2022-07-27 | 2022-09-20 | 广东益可维生物技术有限公司 | Probiotic composition with effects of resisting claustrophobia, protecting stomach and promoting digestion and eliminating stagnation and application thereof |
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| CN102960736A (en) * | 2012-12-05 | 2013-03-13 | 安徽燕之坊食品有限公司 | Health-care food and preparation method thereof |
| CN104187611A (en) * | 2014-07-26 | 2014-12-10 | 胡安然 | Total nutrient formula food for gastrointestinal malabsorption |
| CN114931217A (en) * | 2022-05-11 | 2022-08-23 | 安徽方敏医药科技股份有限公司 | Probiotic freeze-dried powder and preparation method thereof |
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