CN115739228A - Micropore plate positioning mechanism for liquid treatment workstation - Google Patents

Abstract

The invention discloses a microporous plate positioning mechanism for a liquid treatment workstation, which comprises a bracket for bearing a microporous plate, wherein the front end and the rear end of the top of the bracket are respectively provided with a first positioning piece, the two sides of the top of the bracket are respectively provided with a second positioning piece, and a driving mechanism for driving the two first positioning pieces and the two second positioning pieces to synchronously move is arranged in the bracket; actuating mechanism includes the motor, the drive shaft, first gear, the second gear, first rack and second rack, the center department in the inside bottom of bracket is installed to the motor, the vertical drive shaft that is connected with of output of motor, the drive shaft top is rotated and is connected in the inside top of bracket, actuating mechanism through setting up, switching component, the cooperation of first setting element and second setting element is used, can fix a position the centre gripping to the micropore board four sides, guarantee that the micropore board of every turn places the uniformity of position on the bracket.

Description

Micropore plate positioning mechanism for liquid treatment workstation

Technical Field

The invention relates to the technical field of liquid treatment workstations, in particular to a positioning mechanism of a microporous plate for a liquid treatment workstation.

Background

At present, sampling and pipetting instruments are widely applied to biological experiments such as biochemistry, molecules, cells and the like, the main function of the instrument is to collect and transfer liquid with a certain volume, a multi-needle pipetting system is one of core mechanisms of a full-automatic liquid treatment workstation and is used for realizing actions such as conveying, extracting, transferring and the like of the liquid among standard liquid containers, and in the use of the modern full-automatic liquid treatment workstation, the most commonly used standard liquid containers are standard liquid containers such as 8-well plates, 96-well plates, 384-well plates and the like. Wherein, the spacing between adjacent holes of standard liquid containers such as 96-hole plates, 384-hole plates and the like which are commonly used in laboratories is 4.5mm at minimum, the volume is about 20-100 microliter, and 8-16 holes are distributed in a single row.

Therefore, a fully automated liquid handling station, in particular a pipetting mechanism therein, requires a high precision and high reproducibility of the simultaneous or separate pipetting actions of a plurality, e.g. eight, pipetting channels within a small spatial range.

Through retrieval, the Chinese patent publication number: CN107570247A discloses an automatic liquid-transfering machine, which comprises a machine body and a movable base arranged on the machine body; the worktable is arranged on the machine body, and a plurality of sample processing areas are arranged on the worktable; the bearing mechanism comprises a carrier plate and a driving rod arranged on the carrier plate, and the carrier plate is arranged on the movable base; the multi-needle pipetting system comprises a plurality of pipetting needles, an adjusting mechanism, a fixing frame and a sensor unit, wherein the adjusting mechanism is used for adjusting the positions and the intervals of the plurality of pipetting needles, and the fixing frame is connected with a support plate through a driving rod in a lifting manner. When needing to gather and shift liquid, place empty micropore board on the support plate earlier, many needles pipetting system operation, adjustment mechanism adjusts the pipetting needle and slides and descend to the reservoir in, move liquid and absorb the back to liquid, adjustment mechanism adjusts the pipetting needle and rises and slide to the micropore board top, adjustment mechanism adjusts the pipetting needle and descends and pours into the micropore board with liquid ration into, the micropore board that the loading has liquid takes away from the support plate through the manipulator, then shifts to other processes, this patent has following defect: when the position production deviation was placed to the micropore board on the support plate, the pipetting needle can touch the micropore board when descending to cause the damage to the pipetting needle, reduce pipetting needle life, and the deviation of position is placed to the micropore board, also can influence the manipulator and to the snatching of micropore board, lead to the manipulator to snatch fixed unstability easily, thereby lead to the risk that the micropore board drops or squints.

Through retrieval, the Chinese patent publication number: CN203037654U discloses a positioning mechanism of an elisa plate, which comprises a body and a cantilever type supporting plate extending from the body, wherein the supporting plate is in a square frame shape, and one end of the supporting plate far away from the body is provided with at least one positioning hole; this internal one can slide to be provided with the thimble of layer board, the thimble set up in set up the spout on the body to can slide in this spout, this patent is used for fixed location to the micropore board, can only carry out the ascending location of fore-and-aft direction to the micropore board, can not avoid the micropore board to appear the ascending removal in left and right directions after the location, causes the micropore board location inaccurate, needs to carry out many times the adjustment to the micropore board and just can pinpoint micropore board and workstation.

Disclosure of Invention

1. Technical problems to be solved by the invention

Aiming at the defects of the prior art, the invention designs the micropore plate positioning mechanism for the liquid processing workstation, and the micropore plate can be positioned and clamped on four sides by matching the driving mechanism, the switching component, the first positioning piece and the second positioning piece, so that the consistency of the position of placing the micropore plate on the bracket every time is ensured.

2. Technical scheme

In order to solve the above technical problem, the present invention provides a microplate positioning mechanism for a liquid handling workstation, comprising a carriage for carrying a microplate, characterized in that: the front end and the rear end of the top of the bracket are respectively provided with a first positioning piece, the two sides of the top of the bracket are respectively provided with a second positioning piece, and a driving mechanism for driving the two first positioning pieces and the two second positioning pieces to synchronously move is arranged in the bracket;

the driving mechanism comprises a motor, a driving shaft, a first gear, a second gear, a first rack and a second rack, the motor is installed at the center of the bottom end in the bracket, the output end of the motor is vertically connected with the driving shaft, the top end of the driving shaft is rotatably connected to the top end in the bracket, the first gear and the second gear are both sleeved on the driving shaft, the second gear is located above the first gear, gear through holes for the driving shaft to pass through are formed in the centers of the first gear and the second gear, the diameter of each gear through hole is larger than that of the driving shaft, the two sides of the first gear are both in meshing connection with the first racks, the two first racks are respectively connected with the two first positioning parts through first connecting rods, the front end and the rear end of the second gear are both in meshing connection with the second racks, and the two first racks are respectively connected with the two second positioning parts through second connecting rods;

when the driving mechanism works, only one of the first gear and the second gear rotates, a cavity is formed in the driving shaft, and a switching component for switching the working states of the first gear and the second gear is arranged in the cavity.

Preferably, the first positioning element comprises a first moving plate, a first positioning plate, a first guide rod, a first limiting plate, a first inductor and a first spring, the first positioning plate is arranged on one side, close to the center of the bracket, of the first moving plate, the first guide rod is fixedly connected to both ends of one side, close to the first moving plate, of the first positioning plate, one end, far away from the first positioning plate, of the first guide rod penetrates through the first moving plate and is fixedly connected with the first limiting plate, the first inductor is installed in the middle position, close to one side of the first positioning plate, of the first moving plate, the first spring is installed between the first positioning plate and the first moving plate, a plurality of rollers are arranged on one side, far away from the first moving plate, of the first positioning plate at equal intervals along the length direction, and the top end of the first connecting rod is fixedly connected with the first moving plate;

the second setting element includes second movable plate, second locating plate, second guide bar, second limiting plate, second inductor and second spring, the second locating plate sets up in the one side that the second movable plate is close to the bracket center, the equal fixedly connected with second guide bar in both ends that the second locating plate is close to second movable plate one side, second locating plate and fixedly connected with second limiting plate are kept away from to the second guide bar, the second inductor is installed to the intermediate position that the second movable plate is close to second locating plate one side to the second movable plate, install the second spring between second locating plate and the second movable plate, the top and the second movable plate fixed connection of second connecting rod.

Preferably, the position corresponding to the first positioning piece on the top of the bracket is provided with a first limiting groove extending from the edge of the bracket to the center, the first connecting rod penetrates through the first limiting groove and is in sliding connection with the first limiting groove, the position corresponding to the second positioning piece on the top of the bracket is provided with a second limiting groove extending from the edge of the bracket to the center, and the second connecting rod penetrates through the second limiting groove and is in sliding connection with the second limiting groove.

Preferably, be provided with first stable sleeve between first gear and the inside bottom of bracket, first stable sleeve bottom mounting is in the bracket, first stable sleeve top is connected with first gear revolve, be provided with second stable sleeve between second gear and the inside top of bracket, second stable sleeve top is fixed in the bracket, second stable sleeve bottom and second gear revolve and be connected.

Preferably, the edges at the front end and the rear end of the top of the bracket are provided with first limiting parts matched with the first positioning parts for use, and the edges at the two sides of the top of the bracket are provided with second limiting parts matched with the second positioning parts for use.

Preferably, the first limiting part comprises a first fixing plate installed on the bracket, a third inductor is installed on one side, close to the first positioning part, of the first fixing plate, the second limiting part comprises a second fixing plate installed on the bracket, and a fourth inductor is installed on one side, close to the second positioning part, of the second fixing plate.

Preferably, the switching component comprises a driving piece, an embedded block, four first abutting pieces and four second abutting pieces, wherein the first abutting pieces are arranged in the cavity of the driving shaft corresponding to the first gears along the circumferential direction, the second abutting pieces are arranged in the cavity of the driving shaft corresponding to the second gears along the circumferential direction, the driving piece is installed at the top end of the inside of the cavity of the driving shaft, the output end of the driving piece is fixedly connected with the embedded block, and the embedded block is arranged between the first abutting pieces and the second abutting pieces.

Preferably, the first abutting part and the second abutting part respectively comprise a stop block and an abutting block arranged on the outer side of the stop block, the cross section of the abutting block is smaller than that of the stop block, a through groove for the abutting block to pass through is formed in the outer wall of the driving shaft, a third spring is installed between the stop block and the inner wall of the stop block, the abutting block on the first abutting part can abut against the inner wall of the gear through hole on the first gear, and the abutting block on the second abutting part can abut against the inner wall of the gear through hole on the second gear.

Preferably, the embedding block is of a cylindrical structure, first sliding inclined planes are arranged at two ends of the embedding block, and second sliding inclined planes matched with the first sliding inclined planes are arranged at the top end of a check block on the first abutting part and the bottom end of a check block on the second abutting part.

Preferably, the top end of the bracket is uniformly provided with a plurality of ball grooves, balls are arranged in the ball grooves in a rolling mode, and the ball parts protrude out of the upper surface of the bracket.

3. Advantageous effects

Compared with the prior art, the invention has the beneficial effects that:

in the embodiment of the invention, through the matched use of the arranged driving mechanism, the switching component, the first positioning piece and the second positioning piece, when the micropore plate is positioned, clamped and fixed, the driving shaft is driven to rotate by the motor, at the moment, the first gear is driven to rotate by the switching component, the second gear is static, so that the two meshed first racks are driven to move oppositely by the first gear, the two first positioning pieces are driven to synchronously approach the micropore plate by the first connecting rod, the front end and the rear end of the micropore plate are positioned and clamped firstly, then the second gear is driven to rotate by the switching component, the first gear is static, so that the two meshed second racks are driven to move oppositely by the second gear, the two second positioning pieces are driven to synchronously approach the micropore plate by the second connecting rod, and then the two sides of the micropore plate are positioned and clamped, so that the four sides of the micropore plate can be positioned and fixed, and the positioning effect of the micropore plate is improved.

Drawings

FIG. 1 is a schematic view of the overall structure of the present invention;

FIG. 2 is a top view of the present invention;

FIG. 3 is a schematic view of the internal structure of the present invention;

FIG. 4 is a cross-sectional view of the drive shaft, first gear and second gear of the present invention;

FIG. 5 is an enlarged view of the structure of the area A in FIG. 4;

FIG. 6 is a schematic view of an insert block according to the present invention;

fig. 7 is a schematic structural view of the first abutting member and the second abutting member of the present invention.

In the figure: 1. a bracket; 101. a first limit groove; 102. a second limit groove; 2. a first positioning member; 201. A first moving plate; 202. a first positioning plate; 203. a first guide bar; 204. a first limit plate; 205. A first inductor; 206. a first spring; 207. a roller; 3. a second positioning member; 301. a second moving plate; 302. a second positioning plate; 303. a second guide bar; 304. a second limiting plate; 305. a second inductor; 306. a second spring; 4. a first limit piece; 401. a first fixing plate; 402. a third inductor; 5. a second limiting member; 501. a second fixing plate; 502. a fourth inductor; 6. a motor; 7. a drive shaft; 701. a through groove; 8. a first gear; 801. a gear through hole; 9. a second gear; 10. a first stabilizing sleeve; 11. a second stabilizing sleeve; 12. a ball bearing; 13. a first rack; 14. a first connecting rod; 15. A second rack; 16. a second connecting rod; 17. a drive member; 18. embedding a block; 19. a first abutting member; 1901. a stopper; 1902. a butting block; 20. a second abutting member; 21. and a third spring.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, rather than all embodiments, and all other embodiments obtained by a person skilled in the art without making creative efforts based on the embodiments of the present invention belong to the protection scope of the present invention.

To facilitate an understanding of the invention, the invention will now be described more fully hereinafter with reference to the accompanying drawings. Several embodiments of the invention are presented in the drawings. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.

It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "left," "right," and the like as used herein are for illustrative purposes only.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.

The embodiment is as follows: this embodiment provides a micropore board positioning mechanism for liquid handling workstation, and this mechanism is arranged in the liquid handling workstation to fix a position the position that the bracket was placed to the micropore board, through fixing a position the centre gripping to the micropore board four sides, guarantees the uniformity that the position was placed on the bracket to the micropore board at every turn.

Referring to fig. 1-7, an embodiment of the present invention provides a microplate positioning mechanism for a liquid processing workstation, including a carrier 1 for carrying a microplate, first positioning members 2 are disposed at front and rear ends of a top of the carrier 1, second positioning members 3 are disposed at two sides of the top of the carrier 1, the microplate is disposed between the two first positioning members 2 and the two second positioning members 3, and positions of the microplate are fixed by the two first positioning members 2 and the two second positioning members 3, so as to ensure consistency of positions of the microplate placed on the carrier 1 each time, avoid positional deviation of the microplate, increase accuracy of transferring liquid by a liquid transferring needle, reduce damage caused by contact between the liquid transferring needle and the microplate, and enable a manipulator of the liquid processing workstation to more accurately take the microplate away from the carrier 1 and then transfer the microplate to other processes;

referring to fig. 1, fig. 2 and fig. 3, in this embodiment, a driving mechanism for driving the two first positioning members 2 and the two second positioning members 3 to move synchronously is disposed inside the bracket 1, and the driving mechanism drives the first positioning members 2 and the second positioning members 3 in a manner that the two first positioning members 2 are driven to position and clamp the microplate, and then the two second positioning members 3 are driven to position and clamp the microplate, so that the consistency of the position of the microplate placed on the bracket 1 at each time is ensured by positioning and clamping the four sides of the microplate.

In a preferred embodiment of the present invention, referring to fig. 3 and 4, the specific structure of the driving mechanism is as follows:

the driving mechanism comprises a motor 6, a driving shaft 7, a first gear 8, a second gear 9, a first rack 13 and a second rack 15, the motor 6 is installed at the center of the bottom end inside the bracket 1, the output end of the motor 6 is vertically connected with the driving shaft 7, the top end of the driving shaft 7 is rotatably connected to the top end inside the bracket 1, the first gear 8 and the second gear 9 are both sleeved on the driving shaft 7, the second gear 9 is located above the first gear 8, the centers of the first gear 8 and the second gear 9 are both provided with a gear through hole 801 for the driving shaft 7 to pass through, the diameter of the gear through hole 801 is larger than that of the driving shaft 7, both sides of the first gear 8 are both engaged with the first racks 13, the two first racks 13 are respectively connected with the two first positioning members 2 through first connecting rods 14, the corresponding positions of the top of the bracket 1 and the first positioning members 2 are provided with first limiting grooves 101 extending from the edge of the bracket 1 to the center, in the embodiment, the first rack 13 is perpendicular to the first positioning members 2, the first limiting grooves 101 are arranged in parallel with the second limiting grooves 102, the second rack 102, the second limiting grooves 102 are arranged in the position where the first positioning members 2 and the second positioning members 2, and the bracket 1, the second rack 102 are connected with the second rack 102, and the second rack 102, and the second rack 15 are arranged in parallel to the bracket 1;

when the driving mechanism works, only one of the first gear 8 and the second gear 9 rotates, a cavity is arranged in the driving shaft 7, and a switching component for switching the working states of the first gear 8 and the second gear 9 is arranged in the cavity.

Particularly, when fixing micropore plate location centre gripping, order about drive shaft 7 through motor 6 and rotate, make first gear 8 rotate through the switching subassembly this moment, second gear 9 is motionless, thereby drive the first rack 13 of two meshings and remove in opposite directions through first gear 8, it is close to the micropore board to drive two first locating part 2 through first connecting rod 14 in step, thereby earlier both ends location centre gripping around the micropore board, then make second gear 9 rotate through the switching subassembly, first gear 8 is motionless, thereby drive the second rack 15 of two meshings and remove in opposite directions through second gear 9, it is close to the micropore board in step to drive two second locating part 3 through second connecting rod 16, thereby fix micropore board both sides location centre gripping again, make can fix micropore board four sides location, improve the location effect to the micropore board.

In some embodiments of the present application, in order to improve the stability of the movement of the first rack 13 and the second rack 15, the first rack 13 and the second rack 15 may be slidably coupled to the inner wall of the bracket 1.

In a preferred example of the present invention, referring to fig. 4, fig. 5, fig. 6 and fig. 7, the specific structure of the switching element is as follows:

the switching component comprises a driving piece 17, an embedded block 18, a first abutting piece 19 and a second abutting piece 20, the number of the first abutting piece 19 is four along the circumferential direction at the position, corresponding to the first gear 8, in the cavity of the driving shaft 7, the number of the second abutting piece 20 is four along the circumferential direction at the position, corresponding to the second gear 9, in the cavity of the driving shaft 7, the driving piece 17 is installed at the top end of the inner part of the cavity of the driving shaft 7, the output end of the driving piece 17 is fixedly connected with the embedded block 18, and the embedded block 18 is arranged between the first abutting piece 19 and the second abutting piece 20;

further, the first abutting part 19 and the second abutting part 20 both include a stopper 1901 and an abutting block 1902 disposed outside the stopper 1901, the cross section of the abutting block 1902 is smaller than that of the stopper 1901, a through groove 701 through which the abutting block 1902 passes is formed in the outer wall of the driving shaft 7, a third spring 21 is installed between the stopper 1901 and the inner wall of the stopper 1901, the abutting block 1902 on the first abutting part 19 can abut against the inner wall of the gear through hole 801 on the first gear 8, and the abutting block 1902 on the second abutting part 20 can abut against the inner wall of the gear through hole 801 on the second gear 9;

furthermore, the embedded block 18 is a cylinder structure, the two ends of the embedded block 18 are both provided with first sliding slopes, the top end of the stop 1901 on the first abutting part 19 and the bottom end of the stop 1901 on the second abutting part 20 are both provided with second sliding slopes which are matched with the first sliding slopes to slide, so that the embedded block 18 can be conveniently moved and placed between the four first abutting parts 19 and the four second abutting parts 20.

Specifically, when the driving mechanism drives the first positioning element 2 to move the two second positioning elements 3, the operating state of the switching component is that the driving element 17 drives the embedded block 18 to move and place between the four first abutting elements 19, so that the abutting block 1902 on the first abutting element 19 abuts against the inner wall of the gear through hole 801 on the first gear 8, at this time, the second abutting element 20 and the second gear 9 are in a separated state, the power generated by the rotation of the driving shaft 7 can be transmitted to the first gear 8, and the first gear 8 is driven to rotate, so that the first positioning element 2 is driven to move, after the first positioning element 2 positions and clamps the microporous plate, the embedded block 18 is driven to move and place between the four second abutting elements 20 through the driving element 17, at this time, the abutting block 1902 on the second abutting element 20 abuts against the inner wall of the gear through hole 801 on the second gear 9, the first abutting element 19 and the first gear 8 are in a separated state, and the power generated by the rotation of the driving shaft 7 can be transmitted to the second gear 9, so as to drive the second abutting element 3 to move, and position and clamp the microporous plate.

In some embodiments of the present application, the driving member 17 is an electric push rod, and in other embodiments, the driving member 17 may be a linear cylinder.

In some embodiments of the present application, four clamping grooves are provided on the inner wall of the gear through hole 801 on the first gear 8 and the second gear 9, which are opposite to the positions of the first abutting member 19 and the second abutting member 20, the clamping grooves and the abutting block 1902 are preferably trapezoidal, the abutting block 1902 can be clamped into the clamping grooves, the stability of the connection between the first abutting member 19 and the first gear 8 and between the second abutting member 20 and the second gear 9 is improved, and the stability of power transmission is caused.

Referring to fig. 3, in the present embodiment, a first stabilizing sleeve 10 is disposed between the first gear 8 and the bottom end inside the bracket 1, the bottom end of the first stabilizing sleeve 10 is fixed inside the bracket 1, the top end of the first stabilizing sleeve 10 is rotatably connected to the first gear 8, the position of the first gear 8 is located by the first stabilizing sleeve 10, so as to ensure the stability of connection between the first gear 8 and the rack, a second stabilizing sleeve 11 is disposed between the second gear 9 and the top end inside the bracket 1, the top end of the second stabilizing sleeve 11 is fixed inside the bracket 1, the bottom end of the second stabilizing sleeve 11 is rotatably connected to the second gear 9, and the position of the second gear 9 is located by the second stabilizing sleeve 11, so as to ensure the stability of connection between the second gear 9 and the rack.

In a preferred example of the present invention, referring to fig. 1 and 2, the first positioning element 2 has the following specific structure:

the first positioning element 2 comprises a first moving plate 201, a first positioning plate 202, a first guide rod 203, a first limit plate 204, a first inductor 205 and a first spring 206, the first positioning plate 202 is arranged on one side of the first moving plate 201 close to the center of the bracket 1, the first guide rod 203 is fixedly connected to both ends of one side of the first positioning plate 202 close to the first moving plate 201, one end of the first guide rod 203 far away from the first positioning plate 202 penetrates through the first moving plate 201 and is fixedly connected with the first limit plate 204, the first inductor 205 is arranged in the middle of one side of the first moving plate 201 close to the first positioning plate 202, the first spring 206 is arranged between the first positioning plate 202 and the first moving plate 201, a plurality of rollers 207 are arranged on one side, away from the first moving plate 201, of the first positioning plate 202 at equal intervals along the length direction, the top end of the first connecting rod 14 is fixedly connected with the first moving plate 201, when the first positioning part 2 fixes the micro-porous plate, the first positioning part 2 is driven by the driving mechanism to approach the micro-porous plate, when the first positioning plate 202 is attached to the outer wall of the micro-porous plate, along with the continuous movement of the first positioning part 2, the interval between the first positioning plate 202 and the first moving plate 201 is reduced, so that the first positioning plate 202 is pressed on the first sensor 205 in a supporting manner, the first sensor 205 transmits a signal to a controller of the liquid processing workstation, the switching control module is controlled to switch the states of the first gear 8 and the second gear 9, the first gear 8 is made to be stationary, and the second gear 9 starts to rotate.

In a preferred example of the present invention, referring to fig. 1 and fig. 2, the second positioning element 3 has the following specific structure:

the second positioning element 3 includes a second moving plate 301, a second positioning plate 302, a second guide rod 303, a second limiting plate 304, a second sensor 305 and a second spring 306, the second positioning plate 302 is disposed on one side of the second moving plate 301 close to the center of the bracket 1, two ends of one side of the second moving plate 301 close to the second positioning plate 302 are fixedly connected with the second guide rod 303, one end of the second guide rod 303 far away from the second positioning plate 302 penetrates through the second moving plate 301 and is fixedly connected with the second limiting plate 304, the second sensor 305 is installed at the middle position of one side of the second moving plate 301 close to the second positioning plate 302, the second spring 306 is installed between the second positioning plate 302 and the second moving plate 301, the top end of the second connecting rod 16 is fixedly connected with the second moving plate 301, when the second positioning element 3 is fixed to the microplate, the second positioning element 3 is driven to be close to the second positioning element 3 by the driving mechanism, when the second positioning element 302 is attached to the outer wall of the second positioning element, the second positioning element 302 is attached to the second positioning element, the spacing between the second positioning element 302 and the second positioning element is reduced along with the second positioning element 3, thereby the spacing between the second positioning element 302 and the second positioning element 305 is transferred to the second sensor 305, the working station control motor for controlling the working station 6, and the working station.

It should be noted that, by providing the plurality of rollers 207 on the first positioning plate 202, after the first positioning member 2 positions and clamps the two ends of the microplate, the microplate can still move along the length direction of the first positioning member 2, so that the second positioning member 3 can position and clamp the two sides of the microplate.

In some embodiments of the present application, please refer to fig. 1 and fig. 2, the edges of the front and rear ends of the top of the bracket 1 are provided with first limiting members 4 used in cooperation with the first positioning members 2, and the edges of the two sides of the top of the bracket 1 are provided with second limiting members 5 used in cooperation with the second positioning members 3;

further, the first limiting member 4 includes a first fixing plate 401 mounted on the bracket 1, a third inductor 402 is mounted on a side of the first fixing plate 401 close to the first positioning member 2, the second limiting member 5 includes a second fixing plate 501 mounted on the bracket 1, and a fourth inductor 502 is mounted on a side of the second fixing plate 501 close to the second positioning member 3.

Particularly, after the completion of adding liquid into the microporous plate, reset first positioning piece 2 and second positioning piece 3 through a driving mechanism, first drive two second positioning pieces 3 through a driving mechanism and keep away from each other, when second positioning piece 3 touches fourth inductor 502, signal transmission is given to the controller of the liquid treatment workstation, control switching assembly work switches the state of first gear 8 and second gear 9, make second gear 9 motionless still, first gear 8 begins to rotate, then drive two first positioning pieces 2 and keep away from each other, when third inductor 402 is touched to first positioning piece 2, control motor 6 stop work, accomplish the fixed removal in location to the microporous plate promptly, thereby the manipulator of the liquid treatment workstation of being convenient for takes away the microporous plate from bracket 1, then shift to other processes.

In some embodiments of the present application, the first sensor 205, the second sensor 305, the third sensor 402, and the fourth sensor 502 are all pressure sensors, and in other embodiments, the first sensor 205, the second sensor 305, the third sensor 402, and the fourth sensor 502 may also be touch sensors.

In a preferred example of the present invention, referring to fig. 1, a plurality of ball grooves are uniformly formed at the top end of a carrier 1, balls 12 are rolled in the ball grooves, and a portion of the balls 12 protrudes from the upper surface of the carrier 1, so that the friction force of a microplate moving on the carrier 1 is reduced by the arranged balls 12, which is helpful for position adjustment when the microplate is positioned.

It should be noted that the first positioning member 2 and the second positioning member 3 are spaced from the upper surface of the carriage 1 by a distance greater than the height of the ball 12 protruding from the upper surface of the carriage 1, so that the ball 12 does not obstruct the movement of the first positioning member 2 and the second positioning member 3.

It should be noted that the first sensor 205, the second sensor 305, the third sensor 402, the fourth sensor 502 and the motor 6 of the microplate positioning mechanism for the liquid handling workstation are electrically connected to the controller of the liquid handling workstation, the control circuit of the controller can be implemented by simple programming by those skilled in the art, and the provision of the power source is well known in the art, so the control mode and the circuit connection are not explained in detail in the present invention.

The operation steps of the micropore plate positioning mechanism for the liquid processing workstation are as follows:

firstly, placing a microporous plate on the top of a bracket 1 and between two first positioning parts 2 and two second positioning parts 3;

step two, the driving shaft 7 is driven to rotate by the motor 6, at the moment, the first gear 8 is driven to rotate by the switching component, the second gear 9 is static, so that the two meshed first racks 13 are driven to move oppositely by the first gear 8, and the two first positioning parts 2 are driven to synchronously approach the microporous plate by the first connecting rod 14;

step three, when the first positioning piece 2 positions and fixes the microporous plate, the driving mechanism drives the first positioning piece 2 to approach the microporous plate, when the first positioning plate 202 is attached to the outer wall of the microporous plate, two ends of the microporous plate are positioned, clamped and fixed, and with the continuous movement of the first positioning piece 2, the distance between the first positioning plate 202 and the first moving plate 201 is reduced, so that the first positioning plate 202 is pressed against the first inductor 205, the first inductor 205 transmits a signal to a controller of the liquid treatment workstation, and the switching component is controlled to work to switch the states of the first gear 8 and the second gear 9, so that the first gear 8 is stationary, and the second gear 9 starts to rotate;

driving two meshed second racks 15 to move oppositely through a second gear 9, and driving two second positioning parts 3 to synchronously approach the microporous plate through a second connecting rod 16;

step five, when the second positioning part 3 positions and fixes the microporous plate, the driving mechanism drives the second positioning part 3 to approach the microporous plate, when the second positioning plate 302 is attached to the outer wall of the microporous plate, the distance between the second positioning plate 302 and the second moving plate 301 is reduced along with the continuous movement of the second positioning part 3, so that the second positioning plate 302 is pressed against the second inductor 305, the second inductor 305 transmits a signal to a controller of the liquid processing workstation, and the motor 6 is controlled to stop working, namely, the positioning and fixing of the four sides of the microporous plate are completed;

step six, liquid adding operation is carried out on the microporous plate through liquid transfer in the liquid treatment workstation;

seventhly, after the micro-porous plate liquid adding is finished, the two second positioning parts 3 are driven to be away from each other through the driving mechanism, when the second positioning parts 3 touch the fourth sensor 502, signals are transmitted to a controller of the liquid treatment workstation, and the switching component is controlled to work to switch the states of the first gear 8 and the second gear 9, so that the second gear 9 is enabled to be still, and the first gear 8 starts to rotate;

step eight, the first gear 8 rotates to drive the two first positioning pieces 2 to be away from each other, and when the first positioning pieces 2 touch the third inductor 402, the motor 6 is controlled to stop working, namely the positioning and fixing of the microporous plate are released;

and step nine, taking the micro-porous plate away from the bracket 1 through a mechanical arm of the liquid treatment workstation, and then transferring to other procedures.

To sum up, this application can guarantee that the micropore board is placed the uniformity of position on the bracket to the centre gripping of micropore board four sides location, avoids micropore board offset, increases the liquid transfer needle and shifts liquid precision, reduces the damage that liquid transfer needle and micropore board contact produced, also makes the manipulator of liquid processing workstation can more accurate take away the micropore board from the bracket, then shifts to other processes.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (10)

1. The utility model provides a micropore board positioning mechanism for liquid handling workstation, is including bracket (1) that is used for bearing the weight of the micropore board, its characterized in that: the front end and the rear end of the top of the bracket (1) are respectively provided with a first positioning piece (2), the two sides of the top of the bracket (1) are respectively provided with a second positioning piece (3), and a driving mechanism for driving the two first positioning pieces (2) and the two second positioning pieces (3) to synchronously move is arranged in the bracket (1);

the driving mechanism comprises a motor (6), a driving shaft (7), a first gear (8), a second gear (9), a first rack (13) and a second rack (15), the motor (6) is arranged at the center of the bottom end in the bracket (1), the output end of the motor (6) is vertically connected with a driving shaft (7), the top end of the driving shaft (7) is rotatably connected with the top end in the bracket (1), the first gear (8) and the second gear (9) are sleeved on the driving shaft (7), the second gear (9) is positioned above the first gear (8), the centers of the first gear (8) and the second gear (9) are both provided with gear through holes (801) for the driving shaft (7) to pass through, the diameter of the gear through hole (801) is larger than that of the driving shaft (7), two sides of the first gear (8) are respectively connected with a first rack (13) in a meshing way, the two first racks (13) are respectively connected with the two first positioning pieces (2) through first connecting rods (14), the front end and the rear end of the second gear (9) are respectively connected with a second rack (15) in a meshed manner, and the second racks (15) of the two first racks (13) are respectively connected with the two second positioning pieces (3) through second connecting rods (16);

when the driving mechanism works, only one of the first gear (8) and the second gear (9) rotates, a cavity is arranged in the driving shaft (7), and a switching component for switching the working states of the first gear (8) and the second gear (9) is arranged in the cavity.

2. The microplate positioning mechanism for a liquid handling workstation of claim 1, wherein: the first positioning piece (2) comprises a first moving plate (201), a first positioning plate (202), a first guide rod (203), a first limiting plate (204), a first inductor (205) and a first spring (206), the first positioning plate (202) is arranged on one side, close to the center of the bracket (1), of the first moving plate (201), the first guide rod (203) is fixedly connected to two ends, close to one side of the first moving plate (201), of the first positioning plate (202), one end, far away from the first positioning plate (202), of the first guide rod (203) penetrates through the first moving plate (201) and is fixedly connected with the first limiting plate (204), the first inductor (205) is arranged in the middle position, close to one side of the first positioning plate (202), of the first moving plate (201), the first spring (206) is arranged between the first positioning plate (202) and the first limiting plate (201), a plurality of rollers (207) are arranged on one side, far away from the first moving plate (201), at equal intervals along the length direction, of one side of the first connecting rod (202), and the top end of the first connecting rod (14) is fixedly connected with the first moving plate (201);

second setting element (3) include second movable plate (301), second locating plate (302), second guide bar (303), second limiting plate (304), second inductor (305) and second spring (306), second locating plate (302) set up in one side that second movable plate (301) are close to bracket (1) center, the equal fixedly connected with second guide bar (303) in both ends that second movable plate (301) one side is close to second locating plate (302), the one end that second locating plate (302) were kept away from in second guide bar (303) runs through second movable plate (301) and fixedly connected with second limiting plate (304), second movable plate (301) are close to the intermediate position of second locating plate (302) one side and install second inductor (305), install second spring (306) between second locating plate (302) and second movable plate (301), the top and second movable plate (301) fixed connection of second connecting rod (16).

3. The microplate positioning mechanism for a liquid handling workstation of claim 1, wherein: the top of the bracket (1) is provided with a first limiting groove (101) extending from the edge of the bracket (1) to the center at the position corresponding to the first positioning piece (2), the first connecting rod (14) penetrates through the first limiting groove (101) and is in sliding connection with the first limiting groove (101), a second limiting groove (102) extending from the edge of the bracket (1) to the center is arranged at the position corresponding to the top of the bracket (1) and the second positioning piece (3), and the second connecting rod (16) penetrates through the second limiting groove (102) and is in sliding connection with the second limiting groove (102).

4. The microplate positioning mechanism for a liquid handling workstation of claim 1, wherein: be provided with first stable sleeve (10) between first gear (8) and the inside bottom of bracket (1), first stable sleeve (10) bottom mounting is in bracket (1), first stable sleeve (10) top is rotated with first gear (8) and is connected, be provided with second stable sleeve (11) between second gear (9) and the inside top of bracket (1), second stable sleeve (11) top is fixed in bracket (1), second stable sleeve (11) bottom is rotated with second gear (9) and is connected.

5. The microplate positioning mechanism for a liquid handling workstation of claim 1, wherein: the edge at both ends all is provided with first locating part (4) with first locating part (2) cooperation use around bracket (1) top, the edge of bracket (1) top both sides all is provided with second locating part (5) with second locating part (3) cooperation use.

6. The microplate positioning mechanism for a liquid handling workstation of claim 5, wherein: first locating part (4) is including installing first fixed plate (401) on bracket (1), third inductor (402) are installed to one side that first fixed plate (401) are close to first locating part (2), second locating part (5) are including installing second fixed plate (501) on bracket (1), fourth inductor (502) are installed to one side that second fixed plate (501) are close to second locating part (3).

7. The microplate positioning mechanism for a liquid handling workstation of claim 1, wherein: switch over the subassembly and include driving piece (17), embedding piece (18), first butt piece (19) and second butt piece (20), first butt piece (19) are located to be equipped with four along the circumferencial direction corresponding first gear (8) in the cavity of drive shaft (7), second butt piece (20) are located to be equipped with four along the circumferencial direction corresponding second gear (9) in the cavity of drive shaft (7), install in the inside top of drive shaft (7) cavity driving piece (17), the output fixedly connected with embedding piece (18) of driving piece (17), embedding piece (18) are arranged in between first butt piece (19) and second butt piece (20).

8. The microplate positioning mechanism of claim 7, wherein: first butt piece (19) and second butt piece (20) all include dog (1901) and set up butt piece (1902) in the dog (1901) outside, the cross section of butt piece (1902) is less than the cross section of dog (1901), set up logical groove (701) that supply butt piece (1902) to pass on the outer wall of drive shaft (7), install third spring (21) between dog (1901) and dog (1901) inner wall, butt piece (1902) on first butt piece (19) can support gear through-hole (801) inner wall on tightly in first gear (8), butt piece (1902) on second butt piece (20) can support gear through-hole (801) inner wall on tightly in second gear (9).

9. The microplate positioning mechanism of claim 8, wherein: the embedded block (18) is of a cylindrical structure, first sliding inclined planes are arranged at two ends of the embedded block (18), and second sliding inclined planes matched with the first sliding inclined planes are arranged at the top end of a stop block (1901) on the first abutting part (19) and the bottom end of a stop block (1901) on the second abutting part (20).

10. The microplate positioning mechanism for a liquid handling workstation of claim 1, wherein: the top of bracket (1) evenly is equipped with a plurality of ball groove, the ball rolls in the ball groove and is provided with ball (12), ball (12) part protrusion in bracket (1) upper surface.

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