CN115529820A - 芯片、微流控装置以及分选目标液滴的方法 - Google Patents
芯片、微流控装置以及分选目标液滴的方法 Download PDFInfo
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Abstract
本公开提供了一种芯片、包括该芯片的微流控装置、以及分选目标液滴的方法。该芯片包括:容纳第一流体的第一容纳部;容纳第二流体的第二容纳部;输送流道,包括第一流道和第二流道,第一流道与第一容纳部连通且第二流道与第二容纳部连通,第一流道与第二流道在汇合点处彼此交叉且连通;以及至少一个收集部。第一流道的一部分包括汇合点并被汇合点分割为两个区段,在每一个区段中,该区段沿着远离汇合点的第一方向逐渐***。第二流道包括汇合点并被汇合点分割为两个区段,在每一个区段中,该区段沿着远离汇合点的第二方向逐渐***。
Description
PCT国内申请,说明书已公开。
Claims (27)
- PCT国内申请,权利要求书已公开。
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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PCT/CN2021/090291 WO2022226791A1 (zh) | 2021-04-27 | 2021-04-27 | 芯片、微流控装置以及分选目标液滴的方法 |
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CN115529820A true CN115529820A (zh) | 2022-12-27 |
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CN202180000922.0A Pending CN115529820A (zh) | 2021-04-27 | 2021-04-27 | 芯片、微流控装置以及分选目标液滴的方法 |
CN202220244666.1U Active CN218281795U (zh) | 2021-04-27 | 2022-01-29 | 微流控芯片、盒体装置、微流控装置 |
CN202210112214.2A Pending CN115245846A (zh) | 2021-04-27 | 2022-01-29 | 微流控芯片、盒体装置、微流控装置 |
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CN202220244666.1U Active CN218281795U (zh) | 2021-04-27 | 2022-01-29 | 微流控芯片、盒体装置、微流控装置 |
CN202210112214.2A Pending CN115245846A (zh) | 2021-04-27 | 2022-01-29 | 微流控芯片、盒体装置、微流控装置 |
Country Status (2)
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CN (3) | CN115529820A (zh) |
WO (1) | WO2022226791A1 (zh) |
Citations (11)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102242055A (zh) * | 2011-06-03 | 2011-11-16 | 博奥生物有限公司 | 一种***活力评价及筛选的方法及其专用微流控芯片装置 |
US20120196288A1 (en) * | 2011-01-27 | 2012-08-02 | Lawrence Livermore National Security, Llc | Chip-Based Droplet Sorting |
CN104549587A (zh) * | 2015-01-20 | 2015-04-29 | 重庆科技学院 | 一种三通道微球筛选芯片及使用方法 |
CN105944775A (zh) * | 2016-06-22 | 2016-09-21 | 苏州汶颢芯片科技有限公司 | 单细胞分离微流控芯片 |
CN107008517A (zh) * | 2017-05-22 | 2017-08-04 | 广东顺德工业设计研究院(广东顺德创新设计研究院) | 微流控芯片及其微滴生成装置 |
CN108949496A (zh) * | 2017-05-18 | 2018-12-07 | 中国科学院大连化学物理研究所 | 一种基于液滴微流控芯片的单细胞分离方法 |
CN109735429A (zh) * | 2019-01-28 | 2019-05-10 | 佛山市铬维科技有限公司 | 微流控芯片及分离多种细胞的***及其分离方法 |
US20200141886A1 (en) * | 2017-05-22 | 2020-05-07 | Arizona Board Of Regents On Behalf Of Arizona State University | Metal electrode based 3d printed device for tuning microfluidic droplet generation frequency and synchronizing phase for serial femtosecond crystallography |
CN111378556A (zh) * | 2018-12-29 | 2020-07-07 | 青岛华大智造普惠科技有限公司 | 微流控芯片及其制备方法、单细胞微液滴的制备方法 |
CN112553063A (zh) * | 2020-12-22 | 2021-03-26 | 苏州缔因安生物科技有限公司 | 一种基于微液滴的集成化数字核酸扩增芯片及其使用方法和应用 |
CN112657565A (zh) * | 2020-12-17 | 2021-04-16 | 京东方科技集团股份有限公司 | 微流控通道及其控制方法、微流控芯片和分析装置 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101687191A (zh) * | 2007-07-03 | 2010-03-31 | Nxp股份有限公司 | 操纵流体微滴的微流控芯片以及方法 |
CN109603932B (zh) * | 2018-12-12 | 2020-11-03 | 深圳大学 | 一种双聚焦微流体芯片 |
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2021
- 2021-04-27 WO PCT/CN2021/090291 patent/WO2022226791A1/zh unknown
- 2021-04-27 CN CN202180000922.0A patent/CN115529820A/zh active Pending
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2022
- 2022-01-29 CN CN202220244666.1U patent/CN218281795U/zh active Active
- 2022-01-29 CN CN202210112214.2A patent/CN115245846A/zh active Pending
Patent Citations (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20120196288A1 (en) * | 2011-01-27 | 2012-08-02 | Lawrence Livermore National Security, Llc | Chip-Based Droplet Sorting |
CN102242055A (zh) * | 2011-06-03 | 2011-11-16 | 博奥生物有限公司 | 一种***活力评价及筛选的方法及其专用微流控芯片装置 |
CN104549587A (zh) * | 2015-01-20 | 2015-04-29 | 重庆科技学院 | 一种三通道微球筛选芯片及使用方法 |
CN105944775A (zh) * | 2016-06-22 | 2016-09-21 | 苏州汶颢芯片科技有限公司 | 单细胞分离微流控芯片 |
CN108949496A (zh) * | 2017-05-18 | 2018-12-07 | 中国科学院大连化学物理研究所 | 一种基于液滴微流控芯片的单细胞分离方法 |
CN107008517A (zh) * | 2017-05-22 | 2017-08-04 | 广东顺德工业设计研究院(广东顺德创新设计研究院) | 微流控芯片及其微滴生成装置 |
US20200141886A1 (en) * | 2017-05-22 | 2020-05-07 | Arizona Board Of Regents On Behalf Of Arizona State University | Metal electrode based 3d printed device for tuning microfluidic droplet generation frequency and synchronizing phase for serial femtosecond crystallography |
CN111378556A (zh) * | 2018-12-29 | 2020-07-07 | 青岛华大智造普惠科技有限公司 | 微流控芯片及其制备方法、单细胞微液滴的制备方法 |
CN109735429A (zh) * | 2019-01-28 | 2019-05-10 | 佛山市铬维科技有限公司 | 微流控芯片及分离多种细胞的***及其分离方法 |
CN112657565A (zh) * | 2020-12-17 | 2021-04-16 | 京东方科技集团股份有限公司 | 微流控通道及其控制方法、微流控芯片和分析装置 |
CN112553063A (zh) * | 2020-12-22 | 2021-03-26 | 苏州缔因安生物科技有限公司 | 一种基于微液滴的集成化数字核酸扩增芯片及其使用方法和应用 |
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Publication number | Publication date |
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WO2022226791A1 (zh) | 2022-11-03 |
CN115245846A (zh) | 2022-10-28 |
CN218281795U (zh) | 2023-01-13 |
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