CN115430041A - Portable NRD nerve response signal generator - Google Patents
Portable NRD nerve response signal generator Download PDFInfo
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- CN115430041A CN115430041A CN202211199469.3A CN202211199469A CN115430041A CN 115430041 A CN115430041 A CN 115430041A CN 202211199469 A CN202211199469 A CN 202211199469A CN 115430041 A CN115430041 A CN 115430041A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0526—Head electrodes
- A61N1/0541—Cochlear electrodes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36036—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of the outer, middle or inner ear
- A61N1/36038—Cochlear stimulation
- A61N1/36039—Cochlear stimulation fitting procedures
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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Abstract
The present invention provides a portable NRD neural response signal generator, comprising: the device comprises a shell, a display screen, a singlechip control circuit mainboard, a side control key and an input/output connector; the display screen is used for displaying the amplitude of the current nerve response signal, the output state of the nerve response signal and the electric quantity of the battery; the single chip microcomputer control circuit main board collects an output voltage signal of an electrode of the cochlear implant and gives a corresponding simulated nerve response signal aiming at the output voltage signal; the side control key is used for starting up operation and selecting and confirming the waveform of the nerve response signal; the input and output connector is used for programming, charging the battery and outputting signals. The invention provides equipment support for checking the accuracy of the nerve response signal measured by the cochlear implant, and solves the problems that the existing nerve response telemetering equipment has large signal interference and amplitude value which cannot meet the requirement; the shape of the waveform can be customized, the minimum amplitude of the output waveform reaches +/-50 mu V, and the waveform is stable and has no external interference.
Description
Technical Field
The invention relates to the technical field of special equipment for NRD (neural response telemetry), in particular to a portable NRD neural response signal generator.
Background
Neural response signals are weak electrical signals made by an organism to external stimuli. The cochlear implant stimulates the cochlea of an organism, and the organism makes a corresponding electrophysiological response.
When the cochlear implant device is actually tested, a special device is required to generate a nerve response signal of a simulated organism to electrical stimulation, so that whether the cochlear implant can accurately measure the electrophysiological response of the organism to the electrical stimulation can be verified.
The existing telemetering equipment for measuring the neural response does not have special equipment for giving the neural response electric signal aiming at the stimulation of the artificial cochlea implant.
Disclosure of Invention
In view of the above, the present invention is directed to developing a portable device for providing a neural response electrical signal only for cochlear implant stimulation, and providing a neural response signal simulating the electrical stimulation of a living being on a cochlear implant, so as to verify whether the cochlear implant can accurately measure the neural response signal.
The present invention provides a portable NRD neural response signal generator, comprising: the display screen is arranged on the shell, the singlechip control circuit mainboard is arranged on the shell, the side control keys are arranged on the singlechip control circuit mainboard, and the input and output connectors are arranged on the singlechip control circuit mainboard; the shell is used for bearing the singlechip control circuit mainboard, the display screen and the battery;
the display screen is arranged on the front surface of the shell and is used for displaying the amplitude of the current nerve response signal, the output state of the nerve response signal and the electric quantity of the battery;
preferably, the display screen adopts a liquid crystal display screen, so that the power consumption is low, the volume is small, and the radiation is low;
the single chip microcomputer control circuit main board is used for collecting an output voltage signal of an electrode of the cochlear implant and giving a corresponding simulated nerve response signal aiming at the output voltage signal;
the side control key is arranged on the side of the front side of the shell and is used for starting up operation and selecting and confirming the waveform of the nerve response signal;
the input and output connector is arranged on the side face of the shell and used for burning programs, charging batteries and outputting signals.
Furthermore, the singlechip control circuit mainboard comprises a charging circuit, a signal conditioning circuit, a DAC analog signal output circuit, an ADC signal acquisition circuit and a one-key starting circuit.
Further, the output state of the neural response signal includes: and in the output state, stopping outputting the state, and outputting the state after waveform switching.
Further, the side control key is arranged on the front side of the housing, and comprises: a power-on key, a confirmation key, a 'previous' key and a 'next' key; the start-up key is used for controlling the power-on and power-off of the equipment of the portable NRD neural response signal generator, and the portable NRD neural response signal generator is started up by long pressing of the start-up key; pressing the power-on key and the 'last' key at the same time, and powering off the equipment; the 'last' key and the 'next' key are used for selecting the amplitude and the waveform of the nerve response signal waveform; the confirm key is used for confirming the output state of the currently output waveform and the waveform after switching.
Furthermore, the battery adopts a lithium battery, and the lowest signal pulse voltage amplitude value sent by the lithium battery reaches +/-50 muV so as to simulate a nerve reaction signal sent by a human cochlea when receiving stimulation.
The lithium battery can isolate the electromagnetic interference brought by commercial power equipment, and is convenient for the measurement of the artificial cochlea implant NRD in the debugging stage.
Further, the input-output connector includes: the device comprises an input port and an output port, wherein the input port adopts a universal Type-C interface and is used for online programming of a program and a charging port of a lithium battery; the output port is used for outputting NRD waveforms to be tested, the two SMA female seats are adopted, and because the output signals are weak electric signals, the SMA female seats with shielding covering grounds are adopted as output pins of nerve response signals to reduce the interference of the signals, and the ground wires are led out independently, so that the grounding is facilitated, and the interference is reduced.
Furthermore, the output port is two SMA interfaces, one is NRD waveform before attenuation (external oscilloscope can be connected to detect the working state of the current nerve response signal generator), and the other is NRD waveform after attenuation for artificial cochlear implant equipment to detect and analyze.
Further, in order to adapt to cochlear implant with different detection capabilities, the provided amplitude values of the neural response signal include 8 optional waveform amplitude ranges, and the waveform amplitude value of the neural response signal is reduced step by step so as to improve the detection accuracy of the cochlear implant.
Further, the single chip microcomputer control circuit main board further comprises: the device comprises an output state indicator lamp, a lithium battery charging and discharging management indicator lamp and a buzzer for operating feedback prompt tone output.
Further, the portable NRD neural response signal generator automatically outputs a neural response waveform according to the stimulation of the cochlear implant when connected to the cochlear implant device, most realistically simulating an actual biological response.
The process of operating the portable NRD neural response signal generator includes the steps of:
starting the device by pressing a start key for a long time, wherein the electric quantity of the display screen displays an initial nerve response signal waveform and current lithium battery electric quantity information;
the user can output the default nerve response waveform displayed in the current interface state through the confirmation key; and/or regulating and switching the waveform shape and the amplitude of the current nerve response signal through a 'previous' key and a 'next' key as required.
The invention simulates nerve reaction signals generated by organisms, can generate weak voltage signals for the detection of the artificial cochlea implant, can randomly adjust the waveform through programming, can display the waveform through a display screen, is convenient for the implant to compare with the actual waveform after the analysis and the processing of read signals, can work for a long time by a high-capacity lithium battery, and can isolate noise interference to the maximum extent.
Compared with the prior art, the invention has the beneficial effects that:
the invention provides equipment support for measuring NRD neural response telemetering of the cochlear implant and checking the accuracy of the measured neural response signal of the cochlear implant, and solves the problems that the existing measuring neural response telemetering has no special equipment, the signal interference of general equipment is large, and the amplitude value cannot meet the requirement; the shape of the waveform can be customized, the minimum amplitude of the output waveform reaches +/-50 mu V, the waveform is stable without external interference, and the method is convenient for measurement in the debugging stage of the NRD of the cochlear implant.
Drawings
Various other advantages and benefits will become apparent to those of ordinary skill in the art upon reading the following detailed description of the preferred embodiments. The drawings are only for purposes of illustrating the preferred embodiments and are not to be construed as limiting the invention.
In the drawings:
FIG. 1 is a general schematic diagram of a portable NRD neural response signal generator of the present invention;
FIG. 2 is a diagram of a main operation interface of a neural response signal generator according to an embodiment of the present invention;
FIG. 3 is a system diagram of the functional module of the internal circuit of the neural response signal generator according to the embodiment of the present invention.
In the drawings, the reference numbers indicate:
1. a power-on key; 2. a buzzer; 3. a BOOT button; 4. an output status indicator light; 5. a confirmation key;
6. a "next" button; 7. the "previous" button; 8. a lithium battery charge and discharge management indicator light; 9. 1.8 inch LCD.
Detailed Description
Reference will now be made in detail to the exemplary embodiments, examples of which are illustrated in the accompanying drawings. When the following description refers to the accompanying drawings, like numbers in different drawings represent the same or similar elements unless otherwise indicated. The implementations described in the exemplary embodiments below do not represent all implementations consistent with the present disclosure. Rather, they are merely examples of apparatus and products consistent with certain aspects of the present disclosure, as detailed in the appended claims.
The terminology used in the present disclosure is for the purpose of describing particular embodiments only and is not intended to be limiting of the disclosure. As used in this disclosure and the appended claims, the singular forms "a," "an," and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. It should also be understood that the term "and/or" as used herein refers to and encompasses any and all possible combinations of one or more of the associated listed items.
It is to be understood that although the terms first, second, third, etc. may be used herein to describe various information, such information should not be limited to these terms. These terms are only used to distinguish one type of information from another. For example, first information may also be referred to as second information, and similarly, second information may also be referred to as first information, without departing from the scope of the present disclosure. The word "if," as used herein, may be interpreted as "at \8230; \8230when" or "when 8230; \823030when" or "in response to a determination," depending on the context.
The embodiments of the present invention will be described in further detail with reference to the accompanying drawings.
An embodiment of the present invention provides a portable NRD neural response signal generator, as shown in fig. 1 and 2, including: the display screen is arranged on the shell, the singlechip control circuit mainboard is arranged on the shell, the side control keys are arranged on the singlechip control circuit mainboard, and the input and output connectors are arranged on the singlechip control circuit mainboard; the shell is used for bearing the singlechip control circuit mainboard, the display screen and the battery;
the display screen is arranged on the front surface of the shell and is used for displaying the amplitude of the current nerve response signal, the output state of the nerve response signal and the electric quantity of the battery;
the output state of the neural response signal includes: in the output state, stopping the output state, and outputting the state after waveform switching;
in the embodiment, the display screen adopts a Liquid Crystal Display (LCD) screen 1.8 inches, so that the power consumption is low, the volume is small, and the radiation is low;
the singlechip control circuit main board is used for collecting an output voltage signal of an electrode of the cochlear implant and giving a corresponding simulated nerve response signal aiming at the output voltage signal;
the side control key is arranged on the side of the front face of the shell and used for starting up operation and selecting and confirming a nerve response signal waveform;
the input and output connector is arranged on the side face of the shell and used for programming, charging the battery and outputting signals.
The single chip microcomputer control circuit main board comprises a charging circuit, a signal conditioning circuit, a DAC analog signal output circuit, an ADC signal acquisition circuit, a one-key starting circuit, an output state indicator lamp 4, a lithium battery charging and discharging management indicator lamp 8 and a buzzer 2 for operating feedback prompt tone output.
Referring to fig. 3, a system structure of the functional module of the internal circuit of the neural response signal generator of this embodiment is shown.
The side control button sets up the front side of shell includes: a power-on key 1, a BOOT key 3, a confirmation key 5, a previous key 7 and a next key 6; the power-on key is used for controlling the power-on and power-off of the equipment of the portable NRD neural response signal generator, and the power is turned on by pressing the power-on key 1 for a long time; simultaneously pressing the power-on key 1 and the 'last' key 7, and powering off the equipment; the 'previous' key 7 and the 'next' key 6 are used for selecting the amplitude and the waveform of a nerve response signal waveform; the confirm key 5 is used for confirming that the waveform is currently output and the output state after the waveform is switched.
The battery adopts a lithium battery, and the lowest signal pulse voltage amplitude value sent by the lithium battery reaches +/-50 mu V so as to simulate a nerve response signal sent by a human cochlea when receiving stimulation.
The lithium battery can isolate the electromagnetic interference brought by commercial power equipment, and is convenient for the measurement of the artificial cochlea implant NRD in the debugging stage.
The input-output connector includes: the device comprises an input port and an output port, wherein the input port adopts a universal Type-C interface and is used for online programming of a program and a charging port of a lithium battery; the output port is used for outputting NRD waveforms to be tested, the two SMA female seats are adopted, and because the output signals are weak electric signals, the SMA female seats with shielding covering grounds are adopted as output pins of nerve response signals to reduce the interference of the signals, and the ground wires are led out independently, so that the grounding is facilitated, and the interference is reduced.
The output port is two SMA interfaces, one is NRD waveform before attenuation (capable of being externally connected with an oscilloscope to detect the working state of the current nerve response signal generator), and the other is NRD waveform after attenuation for detection and analysis of the artificial cochlear implant equipment.
In order to adapt to the cochlear implant with different detection capabilities, the provided amplitude values of the neural response signals comprise 8 optional waveform amplitude value ranges, and the waveform amplitude values of the neural response signals are reduced step by step so as to improve the detection accuracy of the cochlear implant.
When connected to a cochlear implant device, the portable NRD neural response signal generator automatically outputs a neural response waveform according to stimulation of the cochlear implant, most realistically simulating an actual biological response.
In this embodiment, the operation process using the portable NRD neural response signal generator includes the following steps:
starting the device by pressing the start key 1 for a long time, wherein the electric quantity of the display screen displays an initial nerve response signal waveform and current lithium battery electric quantity information;
the user can output the default nerve response waveform displayed in the current interface state through the enter key 5; and/or, the wave shape and the amplitude of the current nerve response signal are adjusted and switched through the 'last' key 7 and the 'next' key 6 according to requirements.
The embodiment of the invention simulates a nerve response signal generated by a living being, can generate a weak voltage signal for detecting the artificial cochlear implant, can randomly adjust the waveform through programming, can display the waveform through a display screen, is convenient for the implant to compare with an actual waveform after the analysis and the processing of a read signal, can work for a long time by a high-capacity lithium battery, and can isolate noise interference to the maximum extent.
The embodiment of the invention provides equipment support for measuring NRD neural response telemetry of the cochlear implant and checking the accuracy of the measured neural response signal of the cochlear implant, and solves the problems that the existing measuring neural response telemetry has no special equipment, the signal interference of general equipment is large, and the amplitude value cannot meet the requirement; the shape of the waveform can be defined by user, the minimum amplitude of the output waveform reaches +/-50 mu V, the waveform is stable without external interference, and the method is convenient for measurement in the debugging stage of the artificial cochlea implant NRD.
So far, the technical solutions of the present invention have been described in connection with the preferred embodiments shown in the drawings, but it is easily understood by those skilled in the art that the scope of the present invention is obviously not limited to these specific embodiments. Equivalent changes or substitutions of related technical features can be made by those skilled in the art without departing from the principle of the invention, and the technical scheme after the changes or substitutions can fall into the protection scope of the invention.
The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention; various modifications and alterations to this invention will become apparent to those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (10)
1. A portable NRD neural response signal generator, comprising: the display screen is arranged on the shell, the singlechip control circuit mainboard is arranged on the shell, the side control keys are arranged on the singlechip control circuit mainboard, and the input and output connectors are arranged on the singlechip control circuit mainboard; the shell is used for bearing the singlechip control circuit mainboard, the display screen and the battery;
the display screen is arranged on the front surface of the shell and used for displaying the amplitude of the current nerve response signal, the output state of the nerve response signal and the electric quantity of the battery;
the single chip microcomputer control circuit main board is used for collecting an output voltage signal of an electrode of the cochlear implant and giving a corresponding simulated nerve response signal aiming at the output voltage signal;
the side control key is arranged on the side of the front face of the shell and used for starting up operation and selecting and confirming a nerve response signal waveform;
the input and output connector is arranged on the side face of the shell and used for programming, charging the battery and outputting signals.
2. The portable NRD neural response signal generator of claim 1, wherein the singlechip control circuit board comprises a charging circuit, a signal conditioning circuit, a DAC analog signal output circuit, an ADC signal acquisition circuit, and a one-key start-up circuit.
3. The portable NRD neural response signal generator of claim 1, wherein said output state of neural response signals includes: and in the output state, stopping outputting the state, and outputting the state after waveform switching.
4. The portable NRD neural response signal generator of claim 1, wherein said side control button is provided on a front side of said housing, comprising: a power-on key, a confirmation key, a 'previous' key and a 'next' key; the start-up key is used for controlling the power-on and power-off of the equipment of the portable NRD neural response signal generator, and the portable NRD neural response signal generator is started up by long pressing of the start-up key; simultaneously pressing a power-on key and a 'last' key, and powering off the equipment; the 'last' key and the 'next' key are used for selecting the amplitude and the waveform of a nerve response signal waveform; the confirmation key is used for confirming that the waveform is currently output and the output state after the waveform is switched.
5. The portable NRD neural response signal generator of claim 1, wherein the battery is a lithium battery, and the amplitude of the signal pulse voltage emitted by the lithium battery reaches at least +/-50 μ V, so as to simulate the neural response signal emitted by a human cochlea when receiving stimulation.
6. The portable NRD neural response signal generator of claim 5, wherein said input-output connector comprises: the device comprises an input port and an output port, wherein the input port adopts a Type-C interface and is used for online programming of a program and a charging port of a lithium battery; the output port is used for outputting NRD waveforms to be tested externally, the SMA female seat with the shielding ground is used as an output pin of the nerve response signal to reduce signal interference, and the ground wire is led out independently, so that grounding is facilitated, and the interference is reduced.
7. The portable NRD neural response signal generator of claim 6, wherein the output port is a two-way SMA interface, one is an NRD waveform before attenuation, and the other is an NRD waveform after attenuation for detection and analysis by an artificial cochlear implant device.
8. The portable NRD neural response signal generator of claim 1, wherein the magnitude of the neural response signal is provided to include 8 selectable waveform magnitude ranges, and the waveform magnitude of the neural response signal is reduced step by step to improve the detection accuracy of the cochlear implant.
9. The portable NRD neural response signal generator of claim 1, wherein said one-chip microcomputer control circuit board further comprises: output status indicator lamp, lithium cell charge and discharge management pilot lamp to and be used for operating the buzzer that the feedback prompt tone was exported.
10. The portable NRD neural response signal generator of claim 1, wherein said portable NRD neural response signal generator automatically outputs a neural response waveform, simulating an actual biological response, according to a stimulation of the cochlear implant when connected to the cochlear implant device.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211199469.3A CN115430041A (en) | 2022-09-29 | 2022-09-29 | Portable NRD nerve response signal generator |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211199469.3A CN115430041A (en) | 2022-09-29 | 2022-09-29 | Portable NRD nerve response signal generator |
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| Publication Number | Publication Date |
|---|---|
| CN115430041A true CN115430041A (en) | 2022-12-06 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211199469.3A Pending CN115430041A (en) | 2022-09-29 | 2022-09-29 | Portable NRD nerve response signal generator |
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| CN (1) | CN115430041A (en) |
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- 2022-09-29 CN CN202211199469.3A patent/CN115430041A/en active Pending
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