CN115253890A - Automatic liquid preparation control method and system applied to medical liquid supply - Google Patents

Automatic liquid preparation control method and system applied to medical liquid supply Download PDF

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Publication number
CN115253890A
CN115253890A CN202210866308.9A CN202210866308A CN115253890A CN 115253890 A CN115253890 A CN 115253890A CN 202210866308 A CN202210866308 A CN 202210866308A CN 115253890 A CN115253890 A CN 115253890A
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China
Prior art keywords
liquid
proportioning
stock solution
automatic
proportioned
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CN202210866308.9A
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Chinese (zh)
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黄生科
黄睿
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Jiangsu Ruike Daqi Robot Co ltd
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Jiangsu Ruike Daqi Robot Co ltd
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Priority to CN202210866308.9A priority Critical patent/CN115253890A/en
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/80Forming a predetermined ratio of the substances to be mixed
    • B01F35/83Forming a predetermined ratio of the substances to be mixed by controlling the ratio of two or more flows, e.g. using flow sensing or flow controlling devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/22Mixing of ingredients for pharmaceutical or medical compositions

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Accessories For Mixers (AREA)

Abstract

The invention relates to an automatic liquid preparation control method and system applied to medical liquid supply, and the method comprises the following specific operations: obtaining the liquid amount of each stock solution to be prepared and the liquid taking information of the mixed liquid amount; judging whether the liquid taking information simultaneously meets the proportioning condition that the liquid amount of each stock solution to be proportioned is respectively higher than the lowest threshold value of the stock solution and the mixed liquid amount is lower than the lowest threshold value of the stock solution; setting a proportioning instruction when the proportioning condition is met; and finally, executing a proportioning instruction to finish liquid preparation. Compared with the prior art, the invention has the following remarkable advantages: an automatic liquid preparation control mode is adopted, proportioning parameter setting and flow rate timing setting are supported, the problem of proportioning errors caused by manual operation is solved, and the function of circulating automatic liquid preparation control is realized; meanwhile, the method also meets the requirement of various liquid proportioning operations, enlarges the application range of the method and has higher practicability.

Description

Automatic liquid preparation control method and system applied to medical liquid supply
Technical Field
The invention relates to the technical field of medical liquid preparation, in particular to an automatic liquid preparation control method and system applied to medical liquid supply.
Background
In the practice of medical production, the mixed solution can be found as the first step and starting point of the production process, and is the source problem of controlling the product quality in the whole production link; mixing different liquids to finally form a mixture which is balanced and stable and can be obtained circularly is difficult work; the traditional manual batching mode is adopted, so that the problems of large proportioning error and poor finished product quality are easily caused. With the wide application of electronic technology, the design of an automatic liquid preparation control system with high proportioning precision and wide application range becomes the development trend of medical production.
Document 1: chinese patent No. CN112295429B discloses a liquid mixer and a mixing method, in which a metering pump also has a liquid proportioning function, but the metering pump has an effect of constantly delivering liquid in the same amount into the liquid mixer by means of an arc-shaped structural feature arranged along a delivery direction of a mixing inlet pipe, and there is no actual basis for liquid flow parameters, resulting in a large liquid proportioning error; meanwhile, the method can only fixedly support the proportion of two liquids, and the application range is narrow.
Disclosure of Invention
The invention aims to provide an automatic liquid preparation control method and system applied to medical liquid supply, which are used for detecting liquid taking information in real time, judging and obtaining proportioning parameters, supporting a plurality of stock solution proportioning modes and meeting the requirement of circulating automatic liquid preparation control.
In order to achieve the purpose, the technical scheme adopted by the invention is as follows:
an automatic liquid preparation control method applied to medical liquid supply comprises the following steps:
acquiring liquid taking information, wherein the liquid taking information comprises the liquid amount of each stock solution to be prepared and the liquid amount of the current mixed liquid;
judging whether the liquid taking information can meet a proportioning condition, wherein the proportioning condition comprises that the liquid volume of each stock solution to be proportioned is higher than the lowest threshold value of the stock solution and the liquid volume of the current mixed liquid is lower than the lowest threshold value of the stock solution;
when the liquid taking information meets the proportioning condition, completing one-time liquid proportioning according to a set proportioning instruction, wherein the proportioning instruction comprises the liquid amount proportioning proportion and the proportioning sequence of the stock solution to be proportioned and the proportioning time of each stock solution to be proportioned.
Further, an automatic liquid preparation control system applied to medical liquid supply comprises liquid taking equipment and an automatic liquid preparation control module connected with the liquid taking equipment, wherein the liquid taking equipment and the automatic liquid preparation control module are communicated through a wireless network to perform data transmission. The liquid taking equipment comprises a stock solution part and a proportioning part, wherein the stock solution part comprises at least two storage spaces, each storage space contains a stock solution to be proportioned, and the proportioning part contains proportioned mixed liquid; the automatic liquid preparation control module comprises a chip control device, a liquid level detection device and a proportioning and conveying device: the liquid level detection device is used for detecting liquid taking information of the liquid taking equipment and sending the liquid taking information to the chip control device; and the chip control device is used for storing the received liquid taking information, generating a proportioning instruction, judging whether the liquid taking information meets the proportioning condition or not, and controlling the proportioning conveying device to execute the proportioning instruction to finish one-time liquid proportioning when the liquid taking information meets the proportioning condition.
Further, the specific liquid preparation process comprises the following steps: opening a liquid level valve corresponding to a storage space where the stock solution to be proportioned in the first sequence is located in the proportioning sequence, and closing the liquid level valve when the conveying time reaches the proportioning time; opening a liquid level valve corresponding to a storage space where the next sequential stock solution to be prepared is located according to the preparation sequence, and closing a cover liquid level valve when the conveying time reaches the preparation time; and finishing the liquid preparation until the conveying of all the stock solutions to be prepared is finished.
Compared with the prior art, the invention has the following remarkable advantages:
1. an automatic liquid preparation control mode is adopted, so that the problem of proportioning errors caused by manual operation is solved, and the proportioning accuracy is improved;
2. the proportioning parameters and the flow rate timing setting are supported, the function of circulating automatic liquid preparation control is realized, and the working efficiency of liquid preparation is improved;
3. the liquid proportioning operation is satisfied, the application range of the automatic liquid preparation control system is expanded, and the practicability is high.
Drawings
FIG. 1 is a schematic diagram of an automatic fluid dispensing control system for use in medical fluid supplies in accordance with the present invention;
FIG. 2 is a schematic flow diagram of an automatic fluid dispensing control method for medical fluid supply according to the present invention;
FIG. 3 is a schematic diagram illustrating a configuration instruction setting process according to an embodiment of the present invention;
FIG. 4 is a schematic diagram of a proportioning operation flow in an embodiment of the present invention.
Detailed Description
Embodiments of the present invention will be described in detail below with reference to the accompanying drawings.
In the embodiment of the present invention, the liquid preparation refers to mixing and proportioning at least two stock solutions, such as a first stock solution and a second stock solution.
As shown in fig. 1, the automatic liquid preparation control system for medical liquid supply of the present invention includes a liquid extraction device and an automatic liquid preparation control module, wherein the liquid extraction device and the automatic liquid preparation control module perform data transmission through bluetooth wireless communication. Wherein:
the liquid taking device comprises a stock solution part and a proportioning part; the stock solution part consists of at least two storage spaces, and each storage space is used for containing stock solution to be prepared; the proportioning part is used for containing the proportioned mixed liquid. The liquid taking apparatus is used as a container for storing liquid, such as a water tank, a water bucket, a bottle, and the like.
The automatic liquid preparation control module comprises a chip control device, a liquid level detection device and a proportioning conveying device. The chip control device is an application program installed on the remote server and used for storing the received liquid taking information, generating a proportioning instruction, judging whether the liquid taking information meets proportioning conditions or not, and controlling the proportioning conveying device to execute the proportioning instruction to finish one-time liquid proportioning when the liquid taking information meets the proportioning conditions.
The liquid level detection device is respectively arranged on the stock solution part and the proportioning part and used for detecting liquid taking information and sending the liquid taking information to the chip control device for data storage, and the detected liquid taking information comprises the liquid amount of each stock solution to be proportioned and the current mixed liquid amount.
The liquid level detection device is connected with the liquid level detection device, the proportioning delivery device comprises water pumps and delivery pipes which are respectively in one-to-one correspondence with stock solutions to be proportioned, a liquid inlet of each water pump is connected with the stock solution part through the delivery pipe, and a liquid outlet of each water pump is connected with the proportioning part through the delivery pipe; each water pump is also provided with a liquid level valve for controlling the on-off of the water pump.
According to the above, as shown in fig. 2, the present invention further provides an automatic dispensing control method for medical fluid supply, comprising the following steps:
step S02: acquiring liquid taking information;
specifically, the obtained liquid taking information includes numerical values of the first stock solution amount, the second stock solution amount, and the current mixed solution amount.
Step S04: setting a proportioning instruction;
specifically, before setting the proportioning instruction, whether the liquid taking information meets the proportioning condition needs to be judged, if yes, the step S06 is executed after the proportioning instruction is set, and if not, the step S02 is executed again;
as shown in fig. 3, in steps S040 to S041, if the blending conditions are satisfied simultaneously that the first raw liquid amount and the second raw liquid amount are respectively higher than the lowest threshold value thereof and the current mixed liquid amount is lower than the lowest threshold value thereof, the process proceeds to step S042; the mixed liquid volume of ratio portion prepares mixed liquid volume for first stoste and second stoste, and concrete computational formula:
Mi=(Qmax-Q)*Pi
in the formula, MiRepresents the required liquid amount of the i-th original liquid to be prepared for the liquid preparation, QmaxRepresents the maximum threshold value of the mixed liquid, Q represents the liquid amount of the current mixed liquid, and PiThe proportion of the i-th original solution to be prepared in the mixed solution is shown.
In steps S043 to S044, the proportioning instruction includes setting parameters such as a proportioning ratio, a proportioning order, and a proportioning time of the first stock solution and the second stock solution; obtaining the prepared mixed liquid amount, and determining the ith stock solution amount according to the set proportion of the first stock solution and the second stock solution, wherein the specific calculation formula is as follows:
Ti=(Mi×Vi)/60
in the formula: t isiRepresenting the delivery duration of the i-th stock solution to be proportioned, MiThe liquid amount V required by the preparation of the ith original liquid to be prepared is showniThe average flow speed of the original liquid to be proportioned of the ith item is expressed;
Vi=Qi/S=Qi/(πd2/4)=4Qi/(πd2)
in the formula: viRepresents the average flow velocity (m/s), Q, of the i-th stock solution to be proportionediRepresents the flow (m) of the ith stock solution to be prepared3and/S), S represents the cross-sectional area (square meter) of the conveying pipe, pi represents the circumferential rate, and d represents the inner diameter (m) of the conveying pipe.
The principle is that proportioning parameters of stock solutions to be proportioned are obtained by distinguishing through different characteristics of liquid, and under the condition that the flow and the cross-sectional area of a delivery pipe of the ith stock solution to be proportioned are determined, the delivery time of the ith stock solution to be proportioned is obtained by calculating the average flow speed of the ith stock solution to be proportioned.
Step S06: and finishing automatic liquid preparation according to the proportioning instruction.
As shown in fig. 4, when the first stock solution is preferentially conveyed, the specific proportioning process is as follows:
in step S061, the liquid level valve of the first dope is opened and the first dope is conveyed for a time period of T1;
in step S062, after the delivery of T1 is ended, the liquid level valve of the first dope is closed and the liquid level valve of the second dope is opened, and the delivery time of the second dope is T2;
in step S063, after the T2 conveyance is finished, the matching is completed.
Specifically, the foregoing proportioning process can also be accomplished by selecting to preferentially deliver the second stock solution.

Claims (8)

1. The automatic liquid preparation control method applied to medical liquid supply is characterized by comprising the following steps: the method comprises the following steps:
acquiring liquid taking information, wherein the liquid taking information comprises the liquid amount of each to-be-prepared stock solution and the liquid amount of the current mixed liquid;
judging whether the liquid taking information can meet a proportioning condition, wherein the proportioning condition comprises that the liquid volume of each stock solution to be proportioned is higher than the lowest threshold value of the stock solution and the liquid volume of the current mixed liquid is lower than the lowest threshold value of the stock solution;
when the liquid taking information meets the proportioning condition, completing primary liquid proportioning according to a set proportioning instruction, wherein the proportioning instruction comprises the liquid amount proportioning proportion and the proportioning sequence of the stock solution to be proportioned and the proportioning time of each stock solution to be proportioned.
2. The automatic fluid dispensing control method for use in medical fluid supplies of claim 1, wherein: the proportioning time of each stock solution to be proportioned is the conveying time of the stock solution to be proportioned, and the calculation formula is Ti=(Mi×Vi) /60, wherein: t isiRepresenting the delivery duration of the i-th stock solution to be proportioned, MiThe liquid amount V of the i th original liquid to be prepared in this time is showniThe average flow rate of the i-th stock solution to be proportioned is shown.
3. The automatic fluid dispensing control method for use in medical fluid supplies of claim 1, wherein: the formula for calculating the liquid amount required by the preparation of the original liquid to be prepared in the ith term is as follows: mi=(Qmax-Q)*PiIn the formula, QmaxRepresents the maximum threshold value of the mixed liquid, Q represents the liquid amount of the current mixed liquid, and PiThe proportion of the i-th original solution to be prepared in the mixed solution is shown.
4. An automatic liquid preparation control system based on the method of any one of claims 1 to 3, characterized in that: including get liquid equipment and with get the automatic liquid control module that joins in marriage that liquid equipment is connected, wherein:
the liquid taking equipment comprises a stock solution part and a proportioning part, wherein the stock solution part consists of at least two storage spaces, each storage space contains a stock solution to be proportioned, and the proportioning part contains proportioned mixed liquid;
the automatic liquid preparation control module comprises a chip control device, a liquid level detection device and a proportioning and conveying device:
the liquid level detection device is used for detecting liquid taking information of the liquid taking equipment and sending the liquid taking information to the chip control device;
the chip control device is used for storing the received liquid taking information, generating a proportioning instruction, judging whether the liquid taking information meets proportioning conditions or not, and controlling the proportioning conveying device to execute the proportioning instruction to finish one-time liquid proportioning when the liquid taking information meets the proportioning conditions.
5. An automatic dispensing control system for use in medical fluid supplies according to claim 4, wherein: the liquid taking information comprises the liquid amount of each original liquid to be prepared and the liquid amount of the current mixed liquid.
6. An automatic dispensing control system for use in medical fluid supplies according to claim 4, wherein: the ratio conveyor includes a plurality of water pumps with the storage space one-to-one of stoste portion, every the inlet of water pump with correspond the storage space of stoste portion is connected, every the liquid outlet of water pump with ratio portion connects.
7. An automatic dispensing control system for use in medical fluid supplies according to claim 6, wherein: and each water pump is also provided with a liquid level valve for controlling the switch of the water pump.
8. The automatic fluid dispensing control method for use in medical fluid supplies of claim 7, wherein: the liquid preparation process comprises the following steps:
opening a liquid level valve corresponding to a storage space where the stock solution to be prepared in the first sequence in the preparation sequence is located, and closing the liquid level valve when the conveying time reaches the preparation time; opening a liquid level valve corresponding to a storage space where the next-order stock solution to be prepared is located according to the proportioning sequence, and closing a cover liquid level valve when the conveying time reaches the proportioning time; and (4) completing liquid preparation until the conveying of all stock solutions to be prepared is completed.
CN202210866308.9A 2022-07-22 2022-07-22 Automatic liquid preparation control method and system applied to medical liquid supply Pending CN115253890A (en)

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Application Number Priority Date Filing Date Title
CN202210866308.9A CN115253890A (en) 2022-07-22 2022-07-22 Automatic liquid preparation control method and system applied to medical liquid supply

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Application Number Priority Date Filing Date Title
CN202210866308.9A CN115253890A (en) 2022-07-22 2022-07-22 Automatic liquid preparation control method and system applied to medical liquid supply

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Publication Number Publication Date
CN115253890A true CN115253890A (en) 2022-11-01

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103203191A (en) * 2012-01-13 2013-07-17 昆山允升吉光电科技有限公司 Automatic dispensing device
CN107732265A (en) * 2017-08-29 2018-02-23 成都安普利菲能源技术有限公司 The high flux preparation system of high flux fluid body and method and electrolyte
CN109925946A (en) * 2019-03-26 2019-06-25 江苏旭龙环境科技有限公司 A kind of proportioner and matching method
CN110731328A (en) * 2019-10-28 2020-01-31 广州极飞科技有限公司 Dispensing device and dispensing system

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103203191A (en) * 2012-01-13 2013-07-17 昆山允升吉光电科技有限公司 Automatic dispensing device
CN107732265A (en) * 2017-08-29 2018-02-23 成都安普利菲能源技术有限公司 The high flux preparation system of high flux fluid body and method and electrolyte
CN109925946A (en) * 2019-03-26 2019-06-25 江苏旭龙环境科技有限公司 A kind of proportioner and matching method
CN110731328A (en) * 2019-10-28 2020-01-31 广州极飞科技有限公司 Dispensing device and dispensing system

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