CN115252060A - Bronchial intervention ultrasonic treatment equipment and intervention method for treating chronic obstructive pneumonia - Google Patents
Bronchial intervention ultrasonic treatment equipment and intervention method for treating chronic obstructive pneumonia Download PDFInfo
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- 238000000034 method Methods 0.000 title claims abstract description 23
- 238000009210 therapy by ultrasound Methods 0.000 title claims abstract description 22
- 206010035664 Pneumonia Diseases 0.000 title abstract description 8
- 230000001684 chronic effect Effects 0.000 title abstract description 8
- 238000001816 cooling Methods 0.000 claims abstract description 75
- 210000000621 bronchi Anatomy 0.000 claims abstract description 71
- 239000000110 cooling liquid Substances 0.000 claims abstract description 25
- 238000002604 ultrasonography Methods 0.000 claims description 74
- 239000000523 sample Substances 0.000 claims description 30
- 230000005540 biological transmission Effects 0.000 claims description 19
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 19
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 claims description 15
- 230000003213 activating effect Effects 0.000 claims description 6
- 238000005452 bending Methods 0.000 claims description 6
- 238000002347 injection Methods 0.000 claims description 5
- 239000007924 injection Substances 0.000 claims description 5
- 239000007788 liquid Substances 0.000 claims description 4
- 230000006378 damage Effects 0.000 abstract description 11
- 230000000694 effects Effects 0.000 abstract description 10
- 210000005037 parasympathetic nerve Anatomy 0.000 abstract description 10
- 208000027418 Wounds and injury Diseases 0.000 abstract description 2
- 208000014674 injury Diseases 0.000 abstract description 2
- 230000002638 denervation Effects 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- 238000002560 therapeutic procedure Methods 0.000 description 5
- 239000000463 material Substances 0.000 description 4
- 238000010586 diagram Methods 0.000 description 3
- 238000003491 array Methods 0.000 description 2
- 230000000415 inactivating effect Effects 0.000 description 2
- 238000007674 radiofrequency ablation Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 208000011623 Obstructive Lung disease Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/320068—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/08—Accessories or related features not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/12—Devices for heating or cooling internal body cavities
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/320068—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic
- A61B2017/320069—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic for ablating tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/08—Accessories or related features not otherwise provided for
- A61B2090/0801—Prevention of accidental cutting or pricking
- A61B2090/08021—Prevention of accidental cutting or pricking of the patient or his organs
Abstract
The invention relates to the technical field of medical equipment, in particular to bronchial interventional ultrasonic treatment equipment and an interventional method for treating chronic obstructive pneumonia. The bronchial interventional ultrasonic treatment device comprises an interventional catheter, a cooling assembly and an ultrasonic assembly; the cooling component comprises a cooling balloon which is connected with the interventional catheter; the cooling balloon is used for injecting cooling liquid and enabling the cooling liquid to be expanded to be attached to the inner wall of the bronchus. In intervention equipment and intervention method of this embodiment, through the cooperation of the cooling module that sets up and supersound subassembly, when the supersound subassembly carries out the ultrasonic focusing treatment to the parasympathetic nerve that is located the certain degree of depth of tissue, the cooling module can cool off and protect the inner wall of bronchus to avoid ultrasonic energy to burn the bronchus wall and arouse the complication, thereby realize not damaging the parasympathetic nerve that is located certain degree of depth in the bronchus under the circumstances of bronchus wall and inactivate, effectively reduce the injury to the bronchus inner wall when interveneeing the treatment, excellent in use effect.
Description
Technical Field
The invention relates to the technical field of medical equipment, in particular to bronchial interventional ultrasonic treatment equipment and an interventional method for treating chronic obstructive pneumonia.
Background
The bronchus targeted denervation is a novel chronic obstructive pneumonia treatment method, and the bronchus parasympathetic nerve is damaged in a bronchus intervention mode, so that the slow obstructive pulmonary disease is improved and treated. Currently, a bronchus targeted denervation operation using a radio frequency ablation method is performed clinically, an interventional catheter is inserted into a bronchus focus part, and the focus part is treated by a bioelectric heating effect generated by releasing a radio frequency current at the front end of the catheter.
However, the parasympathetic nerve of the bronchus is usually located in the deep part of the bronchus tissue, and is still a certain distance away from the inner wall of the bronchus, and heat is transferred from the bronchial wall to the inside of the bronchus during the radio frequency ablation process, so that when the parasympathetic nerve is damaged, the tissue of the inner wall of the bronchus is easily damaged, and the risk of causing complications is also caused.
Therefore, how to improve the damage to the bronchial wall in the process of performing the bronchial targeted denervation is an important issue to be solved in the industry.
Disclosure of Invention
The invention provides a bronchus interventional ultrasonic treatment device and an interventional method for treating chronic obstructive pneumonia, which are used for solving the problem that the inner wall tissues of bronchus are easy to be damaged in the traditional bronchus targeted denervation operation.
The invention provides a bronchial interventional ultrasonic treatment device for treating chronic obstructive pneumonia, which comprises:
an interventional catheter;
the cooling component comprises a cooling balloon with a liquid injection cavity arranged inside, and the cooling balloon is connected to one end of the interventional catheter; the cooling balloon is used for injecting cooling liquid and expanding the cooling liquid, and the cooling balloon can be attached to the inner wall of the bronchus after being expanded; and
the ultrasonic assembly comprises an ultrasonic host and a focused ultrasonic transducer, the focused ultrasonic transducer is contained in the cooling balloon, and the ultrasonic host is connected with the focused ultrasonic transducer through signals.
According to one embodiment of the invention, the focused ultrasound transducer is a single-array-element focused ultrasound probe, a linear array focused ultrasound probe or an area array focused ultrasound probe.
According to an embodiment of the invention, the interventional device further comprises a rotating assembly including a rotary drive and a torque transmission coil, the torque transmission coil being at least partially elastic and being connected to the rotary drive and the focused ultrasound transducer, respectively, the rotary drive being configured to drive the focused ultrasound transducer to rotate so as to adjust a treatment region of focused ultrasound of the focused ultrasound transducer.
According to one embodiment of the invention, the focused ultrasound transducer comprises a ring array focused ultrasound probe.
According to one embodiment of the invention, the cooling assembly further comprises a water circulation pump connected to the cooling balloon by a conduit and adapted to drive the cooling liquid to circulate within the cooling balloon.
According to an embodiment of the present invention, the interventional device further comprises a bending handle, an output end of which is connected to the interventional catheter and is used for driving the interventional catheter to bend.
The invention also provides a bronchial intervention method for treating chronic obstructive pneumonia, which comprises the following steps:
providing an interventional catheter and a cooling balloon, wherein the cooling balloon is connected to one end of the interventional catheter, a focusing ultrasonic transducer is arranged in the interventional catheter, and the interventional catheter is placed at a preset position in a bronchus;
injecting a cooling liquid into the cooling balloon;
and starting the focused ultrasonic transducer, and emitting high-energy focused ultrasonic waves to the tissues of the bronchus at the preset position.
According to one embodiment of the invention, the step of injecting a cooling liquid into the cooling balloon comprises the steps of:
and starting a circulating water pump, injecting cooling liquid into the cooling balloon through the circulating water pump, and driving the cooling liquid to form circulation in the cooling balloon.
According to an embodiment of the present invention, the step of activating the focused ultrasound transducer and emitting high-energy focused ultrasound waves to the tissue of the bronchus at the preset position comprises the steps of:
starting the focused ultrasonic transducer, wherein the focused ultrasonic transducer is a single-array-element focused ultrasonic probe, a linear array focused ultrasonic probe or an area array focused ultrasonic probe;
providing a rotating assembly, wherein the output end of the rotating assembly is connected with the focused ultrasonic transducer;
emitting ultrasonic waves to the tissues of the bronchus at the preset position, wherein the rotating assembly is used for driving the focused ultrasonic transducer to rotate relative to the interventional catheter so as to adjust the treatment area of the focused ultrasonic transducer.
According to an embodiment of the present invention, the step of activating the focused ultrasound transducer and emitting ultrasound waves to the tissue of the bronchus at the preset position comprises the steps of:
activating the focused ultrasound transducer, wherein the focused ultrasound transducer comprises a circular array focused ultrasound probe;
and transmitting focused ultrasonic waves to the tissues of the bronchus at the preset position, and realizing automatic beam rotation scanning and focusing at the preset position by exciting a specific transducer unit of the annular array focused ultrasonic probe.
The embodiment of the invention has the following beneficial effects:
in the intervention equipment and the intervention method of the embodiment, through the cooperation of the arranged cooling assembly and the ultrasonic assembly, when the ultrasonic assembly carries out ultrasonic focusing treatment on parasympathetic nerves at a certain depth of a tissue, the cooling assembly can cool and protect the inner wall of a bronchus to avoid ultrasonic energy from burning the wall of the bronchus to cause complications, thereby inactivating the parasympathetic nerves at a certain depth in the bronchus under the condition of not damaging the wall of the bronchus, effectively reducing the damage to the inner wall of the bronchus during the intervention treatment, and having good use effect.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
Wherein:
FIG. 1 is a flow chart of a method of bronchial intervention for the treatment of chronic obstructive pulmonary disease in an embodiment of the present invention;
FIG. 2 is a schematic structural diagram of a bronchial interventional system in accordance with an embodiment of the present invention;
FIG. 3 is a schematic diagram of a focused ultrasound transducer in accordance with an embodiment of the invention;
FIG. 4 is a flow chart of a method of bronchial intervention for treating chronic obstructive pulmonary disease in an embodiment of the present invention;
FIG. 5 is a schematic view of a bronchial interventional system in another embodiment of the invention;
FIG. 6 is a schematic structural diagram of a focused ultrasound transducer in another embodiment of the invention;
FIG. 7 is a flow chart of a method of bronchial intervention for the treatment of chronic obstructive pulmonary disease in another embodiment of the present invention;
reference numerals:
10. a bronchial interventional ultrasound treatment device;
100. an interventional catheter; 210. cooling the balloon; 211. a liquid injection cavity; 220. a water circulating pump; 310. a focused ultrasound transducer; 320. an ultrasonic host; 410. a rotary drive member; 420. a torque transmitting coil;
500. a bending adjusting handle;
600. and (4) a server.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention clearer, the technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings, and it is obvious that the described embodiments are some, but not all embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1 to 7, an embodiment of the present invention provides a bronchial interventional ultrasound treatment device 10 for treating chronic obstructive pulmonary disease, which includes an interventional catheter 100, a cooling assembly and an ultrasound assembly; interventional catheter 100 serves as a carrier element to house and place into the bronchi portions of the cooling assembly and ultrasound assembly; the cooling component comprises a cooling balloon 210 with an injection cavity 211 arranged inside, and the cooling balloon 210 is connected to one end of the interventional catheter 100; the cooling balloon 210 is used for injecting cooling liquid and expanding the cooling liquid, and the cooling balloon 210 can be attached to the inner wall of the bronchus after being expanded; the ultrasonic assembly comprises an ultrasonic host 320 and a focused ultrasonic transducer 310, wherein the focused ultrasonic transducer 310 is accommodated in the cooling balloon 210, and the ultrasonic host 320 is in signal connection with the focused ultrasonic transducer 310.
In the ultrasonic therapy equipment 10 is intervene to bronchus of this embodiment, through the cooperation of the cooling module that sets up and supersound subassembly, when the supersound subassembly carries out the ultrasonic focusing treatment, the cooling module can cool off and protect the inner wall of bronchus to avoid energy transfer to the bronchus wall and arouse the complication, thereby realize inactivating parasympathetic nerve under the condition of not haring the bronchus wall, effectively reduce the injury to bronchus inner wall noise when interveneeing the treatment, excellent in use effect.
In this embodiment, the cooling balloon 210 may be made of a flexible material, and the cooling balloon 210 may be expanded and attached to the inner wall of the bronchus by injecting a cooling liquid into the liquid injection cavity 211 of the cooling balloon 210, at this time, heat on the inner wall of the bronchus may be conducted and dissipated through the cooling liquid, and meanwhile, the cooling balloon 210 may also assist the interventional catheter 100 to be fixed in the bronchus after being expanded, so as to ensure the accuracy of the treatment position of the focused ultrasound transducer 310.
Specifically, referring to fig. 3 and 6, the cooling assembly further includes a water circulation pump 220, and the water circulation pump 220 is connected to the cooling balloon 210 through a pipe and is used for driving the cooling liquid to circulate in the cooling balloon 210.
In this embodiment, the cooling balloon 210 is preferably connected to the circulating water pump 220 through a flexible pipe, and the cooling balloon 210 is communicated with the circulating water pump 220, and after the circulating water pump 220 is started, the cooling liquid can be driven to enter the cooling balloon 210 through the flexible pipe and cool and protect the inner wall of the bronchus, so that compared with the conventional bronchus targeted denervation, when the bronchus interventional ultrasonic therapy apparatus 10 of the present invention is used, the damage of the radio frequency energy of the focused ultrasonic transducer 310 to the inner wall of the bronchus can be effectively avoided, and the therapeutic effect is improved.
Further, the bronchial interventional ultrasonic treatment device 10 further comprises a bending adjusting handle 500, and an output end of the bending adjusting handle 500 is connected to the interventional catheter 100 and is used for driving the interventional catheter 100 to bend.
From this setting, when using the bronchial intervention ultrasonic therapy device 10 of this embodiment, at first put into the bronchus intervention pipe 100, can adjust the bending degree of intervention pipe 100 and the orientation of intervention pipe 100 through operation accent curved handle 500 to make focused ultrasound transducer 310 can aim at the predetermined position of treating in the bronchus, thereby improve focused ultrasound transducer 310's treatment precision, it can effectively improve the treatment of bronchial intervention ultrasonic therapy device 10 to be assisted with the cooling effect of cooling balloon 210.
Referring to fig. 3 and 4, the focused ultrasound transducer 310 is a single-element focused ultrasound probe, a linear array focused ultrasound probe, or an area array focused ultrasound probe.
Further, in the present embodiment, the bronchial intervention ultrasound treatment device 10 further includes a rotation assembly, the rotation assembly includes a rotation driver 410 and a torque transmission coil 420, the torque transmission coil 420 is at least partially elastic, the torque transmission coil 420 is respectively connected to the rotation driver 410 and the focused ultrasound transducer 310, and the rotation driver 410 is configured to drive the focused ultrasound transducer 310 to rotate so as to adjust the treatment region of the focused ultrasound transducer 310.
When the bronchial intervention ultrasonic treatment device 10 of the present embodiment is used, the torque transmission coil 420 can be driven to rotate by starting the rotary driving member 410, and after the driving force of the rotary driving member 410 overcomes the elastic force of the torque transmission coil 420, the torque transmission coil 420 can drive the focused ultrasonic transducer 310 to rotate, so as to adjust the orientation of the focused ultrasonic transducer 310, thereby improving the treatment range of the focused ultrasonic transducer 310.
Meanwhile, the torque transmission coil 420 is used for connecting the rotary driving piece 410 and the focused ultrasonic transducer 310, and the torque transmission coil 420 can buffer the torsion of the focused ultrasonic transducer 310 so as to reduce the damage to the interventional catheter 100, the cooling balloon 210 or the inner wall of the bronchus, and the use effect is good.
Referring to fig. 6 and 7, in another embodiment, the focused ultrasound transducer 310 comprises a ring array focused ultrasound probe.
In this embodiment, the focused ultrasound transducer 310 can emit focused ultrasound energy in a direction of 360 ° by using the annular array focused ultrasound probe, so as to improve the treatment range of the focused ultrasound transducer 310, and the interventional catheter 100 and the focused ultrasound transducer 310 can have a more compact structure after being combined, so that the damage to the patient caused by the interventional catheter 100 being placed in the bronchus is reduced, the purpose of minimally invasive treatment is achieved, and the use effect is good.
In some embodiments, the ultrasound transducer may also include other types of focused ultrasound probes besides linear arrays and annular arrays, and the material may be PZT ceramics, composite materials, CMUTs or PMUTs, etc.
In some embodiments, the bronchial interventional ultrasound treatment device 10 further includes a server 600, and the server 600 is in signal connection with the circulating water pump 220, the ultrasound host 320 and the rotary driving member 410 and is used for controlling any one or more of the circulating water pump 220, the ultrasound host 320 and the rotary driving member 410 to start, in a use process, the server 600 may include a control chip, a storage device and the like, and the operation of the bronchial interventional ultrasound treatment device 10 may be correspondingly controlled through a built-in preset program and an external control instruction input; specifically, the server 600 may obtain the external control signal in a wireless or wired manner, which is not described herein.
Referring to fig. 1 to 7, the present invention also provides a bronchial interventional method for treating chronic obstructive pulmonary disease, which includes the steps of:
step S100, providing an interventional catheter 100 and a cooling balloon 210, wherein the cooling balloon 210 is connected to one end of the interventional catheter 100, a focusing ultrasonic transducer 310 is arranged inside the interventional catheter 100, and the interventional catheter 100 is placed at a preset position in a bronchus;
step S200, injecting cooling liquid into the cooling balloon 210;
step S300, starting the focused ultrasonic transducer 310, and emitting high-energy focused ultrasonic waves to the tissues of the bronchus at the preset position.
In the intervention method of the embodiment, through the cooperation of the arranged cooling assembly and the ultrasonic assembly, when the ultrasonic assembly carries out ultrasonic focusing treatment on parasympathetic nerves at a certain depth of a tissue, the cooling assembly can cool and protect the inner wall of a bronchus to avoid complication caused by the fact that focused ultrasonic energy burns the bronchus wall, so that the parasympathetic nerves at a certain depth in the bronchus are inactivated under the condition that the bronchus wall is not damaged, the damage to the noise of the inner wall of the bronchus during the intervention treatment is effectively reduced, and the use effect is good.
Specifically, referring to fig. 3 and 6, in the intervention method, the step S200 further includes the steps of: and starting the circulating water pump 220, injecting cooling liquid into the cooling balloon 210 through the circulating water pump 220, and driving the cooling liquid to be circularly conveyed in the cooling balloon 210.
In this embodiment, the cooling balloon 210 is preferably connected to the circulating water pump 220 through a flexible pipe, and the cooling balloon 210 is communicated with the circulating water pump 220, and after the circulating water pump 220 is started, the cooling liquid can be driven to enter the cooling balloon 210 through the flexible pipe and cool and protect the inner wall of the bronchus, so that compared with the conventional bronchus targeted denervation, when the bronchus interventional ultrasonic therapy apparatus 10 of the present invention is used, the damage of the ultrasonic energy of the focused ultrasonic transducer 310 to the inner wall of the bronchus can be effectively avoided, and the therapeutic effect is improved.
Referring to fig. 3 to 5, in an embodiment, the step S300 includes the following steps:
step S311, starting the focused ultrasound transducer 310, wherein the focused ultrasound transducer 310 is a single-array element focused ultrasound probe, a linear array focused ultrasound probe, or an area array focused ultrasound probe;
step S312, providing a rotating assembly, wherein an output end of the rotating assembly is connected to the focused ultrasonic transducer 310;
step S313, emitting ultrasonic waves to the tissue of the bronchus at the preset position, wherein the rotating component is used for driving the focused ultrasonic transducer 310 to rotate relative to the interventional catheter 100.
When the bronchial intervention ultrasonic treatment device 10 of the present embodiment is used, the rotational driving member 410 is activated to rotate the focused ultrasonic transducer 310, so as to adjust the orientation of the focused ultrasonic transducer 310, thereby increasing the treatment range of the focused ultrasonic transducer 310. In a preferred embodiment, the rotating assembly further includes a torque transmission coil 420, and the focused ultrasound transducer 310 is connected to the rotary driving member 410 through the torque transmission coil 420, when the rotary driving member 410 is started, the torque transmission coil 420 is driven to rotate, and when the driving force of the rotary driving member 410 overcomes the elastic force of the torque transmission coil 420, the torque transmission coil 420 can drive the focused ultrasound transducer 310 to rotate.
Meanwhile, the torque transmission coil 420 is connected with the rotary driving piece 410 and the focused ultrasonic transducer 310, and the torque transmission coil 420 can buffer the torsion of the focused ultrasonic transducer 310 so as to reduce the damage to the interventional catheter 100, the cooling balloon 210 or the inner wall of the bronchus, and the use effect is good.
In another embodiment, step S300 includes the steps of:
step S321, starting the focused ultrasound transducer 310, where the focused ultrasound transducer 310 includes a ring array focused ultrasound probe;
step S322, transmitting ultrasonic waves to the tissues of the bronchus at the preset position, and realizing 360-degree scanning and focusing at the preset position by exciting a specific unit of the annular array focusing ultrasonic probe.
In this embodiment, the focused ultrasound transducer 310 can emit focused ultrasound energy in a direction of 360 ° by using the ring array focused ultrasound probe, so as to improve the treatment range of the focused ultrasound transducer 310, and the interventional catheter 100 and the focused ultrasound transducer 310 can have a more compact structure after being combined, so that the damage to the patient caused by the interventional catheter 100 being placed in the bronchus is reduced, the purpose of minimally invasive treatment is achieved, and the use effect is good.
In the description of the embodiments of the present invention, it should be noted that the terms "central", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of description and simplicity of description, but do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the embodiments of the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the embodiments of the present invention, it should be noted that, unless explicitly stated or limited otherwise, the terms "connected" and "connected" are to be interpreted broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; may be directly connected or indirectly connected through an intermediate. Specific meanings of the above terms in the embodiments of the present invention can be understood in specific cases by those of ordinary skill in the art.
In embodiments of the invention, unless expressly stated or limited otherwise, the first feature "on" or "under" the second feature may be directly contacting the first and second features or indirectly contacting the first and second features through intervening media. Also, a first feature "on," "above," and "over" a second feature may be directly on or obliquely above the second feature, or simply mean that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature may be directly under or obliquely under the first feature, or may simply mean that the first feature is at a lesser elevation than the second feature.
In the description herein, references to the description of the term "one embodiment," "some embodiments," "an example," "a specific example," or "some examples," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of an embodiment of the invention. In this specification, the schematic representations of the terms used above are not necessarily intended to refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples. Moreover, various embodiments or examples and features of various embodiments or examples described in this specification can be combined and combined by one skilled in the art without being mutually inconsistent.
Finally, it should be noted that: the above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.
Claims (10)
1. A bronchial interventional ultrasound treatment device for the treatment of chronic obstructive pulmonary disease, comprising:
an interventional catheter;
the cooling component comprises a cooling balloon, the interior of the cooling balloon is provided with a liquid injection cavity, and the cooling balloon is connected to one end of the interventional catheter; the cooling balloon is used for injecting cooling liquid and expanding the cooling balloon, and the cooling balloon can be attached to the inner wall of the bronchus after being expanded; and
the ultrasonic assembly comprises an ultrasonic host and a focused ultrasonic transducer, the focused ultrasonic transducer is contained in the cooling balloon, and the ultrasonic host is connected with the focused ultrasonic transducer through signals.
2. Bronchial interventional ultrasound treatment device for the treatment of chronic obstructive pulmonary disease according to claim 1, characterized in that the focused ultrasound transducer is a single-array element focused ultrasound probe, a linear array focused ultrasound probe or an area array focused ultrasound probe.
3. A bronchial interventional ultrasound treatment device for the treatment of chronic obstructive pulmonary disease according to claim 2, characterized in that the interventional device further comprises a rotating assembly comprising a rotating drive and a torque transmission coil, the torque transmission coil being at least partly elastic and being connected to the rotating drive and the focused ultrasound transducer, respectively, the rotating drive being adapted to drive the focused ultrasound transducer in rotation for adjusting the focused ultrasound treatment area of the focused ultrasound transducer.
4. A bronchial interventional ultrasound treatment device for the treatment of chronic obstructive pulmonary disease according to claim 1, characterized in that the focused ultrasound transducer comprises a ring array focused ultrasound probe.
5. A bronchial interventional ultrasound treatment device for the treatment of chronic obstructive pulmonary disease according to claim 1, wherein the cooling assembly further comprises a circulating water pump connected to the cooling balloon by a conduit and adapted to drive the cooling liquid to circulate within the cooling balloon.
6. A bronchial interventional ultrasound treatment device for the treatment of chronic obstructive pulmonary disease according to claim 1, characterized in that the interventional device further comprises a bending handle, an output end of which is connected to the interventional catheter and is used for driving the interventional catheter to bend.
7. A method of bronchial intervention for the treatment of chronic obstructive pulmonary disease, comprising the steps of:
providing an interventional catheter and a cooling balloon, wherein the cooling balloon is connected to one end of the interventional catheter, a focusing ultrasonic transducer is arranged in the interventional catheter, and the interventional catheter is placed at a preset position in a bronchus;
injecting a cooling liquid into the cooling balloon;
and starting the focused ultrasonic transducer, and transmitting high-energy focused ultrasonic waves to the tissues of the bronchus at the preset position.
8. A bronchial interventional method for the treatment of chronic obstructive pulmonary disease according to claim 7, characterized in that the step of injecting a cooling liquid inside the cooling balloon comprises the steps of:
and starting a circulating water pump, injecting cooling liquid into the cooling balloon through the circulating water pump, and driving the cooling liquid to form circulation in the cooling balloon.
9. A method of bronchial intervention for the treatment of chronic obstructive pulmonary disease as claimed in claim 7, wherein said step of activating said focused ultrasound transducer and emitting high energy focused ultrasound waves to the tissue of said bronchi in said preset position comprises the steps of:
starting the focused ultrasonic transducer, wherein the focused ultrasonic transducer is a single-array element focused ultrasonic probe, a linear array focused ultrasonic probe or an area array focused ultrasonic probe;
providing a rotating assembly, wherein the output end of the rotating assembly is connected with the focused ultrasonic transducer;
emitting ultrasonic waves to the tissues of the bronchus at the preset position, wherein the rotating assembly is used for driving the focused ultrasonic transducer to rotate relative to the interventional catheter so as to adjust the treatment area of the focused ultrasonic transducer.
10. The bronchial interventional method for the treatment of chronic obstructive pulmonary disease according to claim 7, wherein the step of activating the focused ultrasound transducer and emitting ultrasound waves to the tissues of the bronchi in the preset positions comprises the steps of:
activating the focused ultrasound transducer, and the focused ultrasound transducer comprises an annular array focused ultrasound probe;
and transmitting focused ultrasonic waves to the tissues of the bronchus at the preset position, and realizing automatic beam rotation scanning and focusing at the preset position by exciting a specific transducer unit of the annular array focused ultrasonic probe.
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| CN105939758A (en) * | 2013-11-04 | 2016-09-14 | 引导干预有限公司 | Method and apparatus for performance of thermal bronchiplasty with unfocused ultrasound |
| US11007001B1 (en) * | 2020-04-07 | 2021-05-18 | Sonivie Ltd. | Devices and methods for reducing parasympathetic nerve activity in patients with a respiratory syndrome |
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2022
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| EP2294991A1 (en) * | 1997-05-16 | 2011-03-16 | Flowcardia Inc. | Therapeutic ultrasound system |
| CN102596320A (en) * | 2009-10-30 | 2012-07-18 | 声特医疗器械有限公司 | Method and apparatus for treatment of hypertension through percutaneous ultrasound renal denervation |
| CN105939758A (en) * | 2013-11-04 | 2016-09-14 | 引导干预有限公司 | Method and apparatus for performance of thermal bronchiplasty with unfocused ultrasound |
| US20210251605A1 (en) * | 2018-06-15 | 2021-08-19 | Ucl Business Ltd | Ultrasound imaging probe |
| US20210316161A1 (en) * | 2020-03-31 | 2021-10-14 | AerWave Medical, Inc. | Method and apparatus for pulmonary interventions |
| US11007001B1 (en) * | 2020-04-07 | 2021-05-18 | Sonivie Ltd. | Devices and methods for reducing parasympathetic nerve activity in patients with a respiratory syndrome |
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