CN115227981A

CN115227981A - Phototherapy device and phototherapy method

Info

Publication number: CN115227981A
Application number: CN202210535559.9A
Authority: CN
Inventors: 陈雷; 李世杰; 许洪畅; 桂思语; 刘增策; 高乐航; 张玉琴; 陈长春
Original assignee: Intelligent Manufacturing Institute of Hefei University Technology
Current assignee: Intelligent Manufacturing Institute of Hefei University Technology
Priority date: 2022-05-17
Filing date: 2022-05-17
Publication date: 2022-10-25

Abstract

The invention discloses phototherapy equipment and a phototherapy method, wherein the phototherapy equipment comprises a scalp phototherapy unit, an eye phototherapy unit, a nasal cavity, an ear canal, an acupuncture point phototherapy unit, an automatic controller and an intelligent terminal: the scalp phototherapy unit is used for emitting first light to the scalp of the patient; the eye phototherapy unit is used for emitting second light to the eyes of the patient; the nasal cavity and nasal canal phototherapy unit is used for emitting third light and fourth light to the nasal cavity and nasal canal of the patient; the Fengchi acupoint and Fengfu acupoint phototherapy unit is used for emitting second wireless light to Fengchi acupoint and Fengfu acupoint of a patient; the whole-body phototherapy unit is used for emitting sixth light to the whole body of the patient, and the input end of the automatic controller is connected with the intelligent terminal and used for sending the target phototherapy unit starting instruction, the target phototherapy unit emitting light source type instruction and the phototherapy duration instruction to the target phototherapy unit. The invention combines Chinese and western medicine and adopts broadband spectrum to treat more widely.

Description

Phototherapy device and phototherapy method

Technical Field

The invention belongs to the technical field of medical instruments and advanced medical treatment, and particularly relates to phototherapy equipment and a phototherapy method.

Background

Parkinson's Disease (PD) and Alzheimer's Disease (AD) are common neurodegenerative diseases in the elderly, seriously threatening human health and quality of life. For PD therapy, PD patients receive dopamine replacement medication with the aim of replacing dopamine lost from the nervous system, with the appearance and diagnosis of first motor symptoms of parkinson's disease. Levodopa is converted to dopamine in the brain, a commonly used first line therapy, and is often very effective in reducing motor symptoms. Dopaminergic treatment of PD patients becomes difficult in the later stages of the disease and can result in side effects such as drug-induced movement disorders and mental disorders, e.g. visual hallucinations. For AD patients, there are few drugs that can be used for the symptomatic treatment of AD, and there are few viable interventions once AD is diagnosed. The current treatment strategies for all PD and AD patients are symptomatic treatments, difficult to slow or stop neuronal degenerative progression, and have high side effects and high costs.

Currently, photobiological modulation (PBM) employs red-near infrared light as a treatment means. Before the advent of LED light sources, low-dose Laser therapy (LLLT) used a Laser as the light source, the Laser being a linear light. With the development of LED light source technology, in recent years, PBM adopts LEDs as a substitute light source, which mainly uses 670nm deep red light for PD and AD treatment, or matches with other near infrared light with different wavelengths, such as 810nm and 850nm. The major site of PD damage is the substantia nigra and striatum of the brain, and the major site of AD damage is the hippocampus. From the perspective of medical equipment and treatment technology, the technical problem of adopting the PBM strategy to treat PD and AD is how to effectively transmit light with treatment efficacy to the diseased region. The equipment that has been used clinically in australia, france, spain, brazil, usa, india etc. is a head-hat style LED lighting device and uses optical fibers to deliver light to the brain through the sinuses. Compared with laser linear light, the emission spectrum of the LED chip is widened, but still is a narrow band spectrum.

Therefore, it is desirable to invent a phototherapy apparatus that can effectively solve the following technical problems:

(1) In the prior art, phototherapy equipment has a single treatment part;

(2) In the prior art, narrow-band spectrum is adopted, and the treatment effect is limited.

Disclosure of Invention

The invention aims to provide phototherapy equipment to solve the following technical problems:

(1) In the prior art, phototherapy equipment has a single treatment part;

In order to achieve the above objects, the present invention provides a phototherapy apparatus for the treatment of parkinson's disease and alzheimer's disease, comprising a scalp phototherapy unit, an eye phototherapy unit, a nasal cavity and sinus phototherapy unit, an ear canal phototherapy unit, a Fengchi and Fengfu phototherapy unit, a whole body phototherapy unit, an automatic controller and an intelligent terminal:

the scalp phototherapy unit is wrapped on the scalp of a patient and used for emitting a first path of light to the scalp of the patient, and the first path of light passes through the scalp of the patient and is transmitted to the brain;

the eye phototherapy unit irradiates the eyes of the patient and is used for emitting a second path of light to the eyes of the patient, and the second path of light is transmitted to the brain through the eyes of the patient;

the nasal cavity and paranasal sinus phototherapy unit is arranged outside the patient and used for emitting a third path of light to the nasal cavity and paranasal sinus of the patient, and the third path of light passes through the nasal cavity and paranasal sinus of the patient and is transmitted to the brain;

the ear canal phototherapy unit is arranged outside the patient and used for emitting fourth light to the ear canal of the patient, and the fourth light is transmitted to the brain through the ear canal of the patient;

the Fengchi acupoint and Fengfu acupoint phototherapy unit is arranged behind the brain of the patient and is used for emitting fifth light to the Fengchi acupoint and the Fengfu acupoint of the patient, and the fifth light passes through the Fengchi acupoint and the Fengfu acupoint of the patient and is transmitted to the brain;

the whole body phototherapy unit is arranged outside the patient and used for emitting sixth light to the whole body of the patient, and the sixth light passes through the skin and the eyes of the patient and is transmitted to the brain;

the input end of the automatic controller is connected with the intelligent terminal and used for receiving a target phototherapy unit starting instruction, a target phototherapy unit emitting light source type instruction and a phototherapy time instruction issued by the intelligent terminal, and the output end of the automatic controller is respectively connected with the scalp phototherapy unit, the eye phototherapy unit, the nasal cavity and nasal sinus phototherapy unit, the ear canal phototherapy unit, the Fengchi acupoint phototherapy unit and the whole body phototherapy unit and used for sending the target phototherapy unit starting instruction, the target phototherapy unit emitting light source type instruction and the phototherapy time instruction to the target phototherapy unit, wherein the target phototherapy unit is at least one of the scalp phototherapy unit, the eye phototherapy unit, the nasal cavity and nasal sinus phototherapy unit, the ear canal phototherapy unit, the Fengchi acupoint and Fengfu acupoint unit and the whole body phototherapy unit;

the first path of light, the second path of light, the third path of light, the fourth path of light and the fifth path of light are red light-near infrared light with the wavelength range of 600-1050nm; the sixth path of light comprises cyan light with the wavelength range of 400-600nm, orange light with the wavelength range of 500-750nm and white light with the wavelength range of 400-780 nm.

Optionally, the scalp phototherapy unit includes a first housing, a first lamp shade, a first illumination module, a reflector and a blower, the first housing is connected to the first lamp shade to form a first cavity, and the first illumination module, the reflector and the blower are disposed in the first cavity; wherein the content of the first and second substances,

the first illumination module is used for emitting the first path of light;

the reflector is used for reflecting the first path of light emitted by the first illumination module, irradiating the reflected light on the scalp of the patient through the first lampshade and transmitting the reflected light to the brain through the scalp of the patient;

the blowing device is used for blowing air to the scalp of the patient so as to increase the comfort of the patient.

Optionally, the eye phototherapy unit includes a second housing, a second lamp shade and a second illumination module, the second housing is connected with the second lamp shade to form a second cavity, the second illumination module is disposed in the second cavity, and a second path of light emitted by the second illumination module passes through the second lamp shade to irradiate on the eyes of the patient and passes through the eyes of the patient to be transmitted to the brain.

Optionally, the nasal sinus phototherapy unit includes a third illumination module and a nasal sinus optical fiber, and the third illumination module is connected to the nasal sinus optical fiber, so that the third light emitted by the third illumination module is irradiated to the nasal sinus of the patient through the nasal sinus optical fiber and is transmitted to the brain through the nasal sinus of the patient;

the ear canal phototherapy unit comprises a fourth illumination module and an ear hole optical fiber, wherein the fourth illumination module is connected with the ear hole optical fiber, so that the fourth illumination module emits fourth path light which passes through the ear hole optical fiber irradiates on the ear canal of the patient and passes through the ear canal of the patient to be transmitted to the brain.

Optionally, the feng chi acupoint and fengfu acupoint phototherapy unit includes a third shell, a third lamp shade and a fifth illumination module, the third shell is connected with the third lamp shade to form a third cavity, the fifth illumination module is disposed in the third cavity, and the fifth path of light emitted by the fifth illumination module irradiates the feng chi acupoint and the fengfu acupoint of the patient through the third lamp shade, passes through the feng chi acupoint and the fengfu acupoint of the patient, and is transmitted to the brain;

whole body phototherapy unit includes the fourth casing, fourth lamp shade and sixth illumination module, the fourth casing with the fourth lamp shade is connected in order to form the fourth cavity, the sixth illumination module is located in the fourth cavity, the sixth illumination module launches the sixth way light passes through the fourth lamp shade shine in the patient is whole body, and passes patient's skin and eyes convey to the brain.

Optionally, the first illumination module includes a first circuit board and a first LED lamp bead, and the first LED lamp bead is disposed on the first circuit board, wherein the first LED lamp bead is configured to emit the red light-near infrared light with the wavelength range of 600-1050nm;

the second illumination module comprises a second circuit board and a second LED lamp bead, and the second LED lamp bead is arranged on the second circuit board and used for emitting the red light-near infrared light with the wavelength range of 600-1050nm;

the third illumination module comprises a third circuit board and a third LED lamp bead, the third LED lamp bead is arranged on the third circuit board, and the third LED lamp bead is used for emitting the red light-near infrared light with the wavelength range of 600-1050nm;

the fifth illumination module comprises a fifth circuit board and a fifth LED lamp bead, the fifth LED lamp bead is arranged on the fifth circuit board, and the fifth LED lamp bead is used for emitting the red light-near infrared light with the wavelength range of 600-1050nm;

the sixth illumination module comprises a sixth circuit board, a sixth LED lamp bead, a seventh LED lamp bead and an eighth LED lamp bead, wherein the sixth LED lamp bead, the seventh LED lamp bead and the eighth LED lamp bead are arranged on the sixth circuit board, the sixth LED lamp bead is used for emitting cyan light within the wavelength range of 400-600nm, the seventh LED lamp bead is used for emitting orange light within the wavelength range of 500-750nm, and the eighth LED lamp bead is used for emitting white light within the wavelength range of 400-780 nm.

Optionally, the phototherapy device further comprises a smart sensing unit;

the intelligent sensing unit comprises a plurality of first sensors, a plurality of second sensors and a camera device;

the plurality of first sensors are respectively installed on the scalp phototherapy unit, the eye phototherapy unit, the nasal cavity and ear canal phototherapy unit, the acupuncture point phototherapy unit and the whole body phototherapy unit and used for collecting the emitted light dose of the light source;

the plurality of second sensors are respectively arranged at target parts of the patient and used for acquiring the physical health state information of the patient;

the camera device is arranged outside the patient and used for collecting the posture information of the patient.

Optionally, the phototherapy device further comprises a central processor;

the input end of the central processing unit is connected with the intelligent sensing unit and used for receiving the light dose data uploaded by the intelligent sensing unit and the body health state information and posture information of the patient, and the output end of the central processing unit is connected with the intelligent terminal and used for transmitting the optimal light dose obtained through machine learning based on the light dose data and the body health state information and posture information of the patient to the intelligent terminal for reference.

Optionally, the phototherapy device further comprises a cloud end;

the cloud is respectively connected with the central processing unit and the intelligent terminal and used for storing a database required by machine learning and transmitting the optimal light dose of each patient to the intelligent terminal.

Optionally, the automatic controller is a wireless bluetooth controller, and the wireless bluetooth controller includes a power circuit, a bluetooth Mesh module U2, a first driving circuit, a second driving circuit, and a third driving circuit;

the input end of the Bluetooth Mesh module U2 is in communication connection with the intelligent terminal and is used for receiving a target phototherapy unit starting instruction, a target phototherapy unit emitting light source type instruction and a phototherapy duration instruction which are issued by the intelligent terminal;

the output end of the bluetooth Mesh module U2 is connected with the input ends of the first driving circuit, the second driving circuit and the third driving circuit, respectively, wherein,

the output end of the first driving circuit is respectively connected with the scalp phototherapy unit, the eye phototherapy unit, the nasal cavity and nasal sinus phototherapy unit, the ear canal phototherapy unit, the Fengchi and Fengfu acupoint phototherapy unit and the whole body phototherapy unit, and the first driving circuit is used for controlling the target phototherapy unit to be opened according to the instruction of starting the target phototherapy unit;

the output end of the second driving circuit is respectively connected with the scalp phototherapy unit, the eye phototherapy unit, the nasal cavity and paranasal sinus phototherapy unit, the ear canal phototherapy unit, the Fengchi and Fengfu phototherapy unit and the whole body phototherapy unit, and the second driving circuit is used for controlling the closing of the target phototherapy unit according to the phototherapy duration instruction;

the output end of the third driving circuit is respectively connected with the scalp phototherapy unit, the eye phototherapy unit, the nasal cavity and paranasal sinus phototherapy unit, the ear canal phototherapy unit, the Fengchi and Fengfu phototherapy unit and the whole body phototherapy unit, and the third driving circuit is used for controlling the light dose of the light source emitted by the target phototherapy unit according to the type instruction of the light source emitted by the target phototherapy unit;

the power circuit is respectively connected with the Bluetooth Mesh module U2, the first driving circuit, the second driving circuit and the third driving circuit and is used for supplying power to the Bluetooth Mesh module U2, the first driving circuit, the second driving circuit and the third driving circuit.

A phototherapy method utilizing the phototherapy apparatus, comprising:

for patients with early stage parkinson's disease and alzheimer's disease, phototherapy the patient using at least one of the first to fifth light paths;

for a patient with intermediate-to late-stage parkinson's disease and alzheimer's disease, phototherapy the patient using at least one of the first to fifth optical paths; and

phototherapy the patient using a sixth light path to treat the patient's affective and psychiatric disorders.

The invention has the beneficial effects that:

the phototherapy device comprises a scalp phototherapy unit, an eye phototherapy unit, a nasal cavity and nasal canal phototherapy unit, a Fengchi point and Fengfu point phototherapy unit, a whole body phototherapy unit, an automatic controller and an intelligent terminal, wherein the application of the Fengchi point and Fengfu point phototherapy unit fully utilizes the traditional Chinese medicine achievement and combines the traditional Chinese medicine and the western medicine, and light is effectively transmitted to the brain stem, the brain substantia nigra and the striatum. Meanwhile, the first path of light, the second path of light, the third path of light, the fourth path of light and the fifth path of light emitted by the phototherapy equipment are red light-near infrared light with the wavelength range of 600-1050nm; the sixth light comprises cyan light with the wavelength range of 400-600nm, orange light with the wavelength range of 500-750nm and white light with the wavelength range of 400-780nm, namely, the phototherapy equipment adopts red light-near infrared light with the wavelength range of 600-1050nm to irradiate the brain for brain treatment; the whole body is irradiated by cyan light with a wavelength range of 400-600nm, orange light with a wavelength range of 500-750nm and white light with a wavelength range of 400-780nm, and the Chinese medicinal composition is used for treating psychosis. All light sources used in the invention adopt fluorescent conversion type LED (pc-LEDs) lamp beads. The emission spectrum of the pc-LEDs is wider than that of a single-chip LED lamp bead, and the requirement of cell broadband spectrum absorption can be better met. Furthermore, pc-LEDs emit light as incoherent light, which is biologically safer than laser light. Therefore, the phototherapy device can better transmit light to the brain lesion part of the PD/AD patient, and the adopted broadband spectrum has wider treatment range, better treatment effect and higher biological safety.

Additional features and advantages of the invention will be set forth in the detailed description which follows.

Drawings

The above and other objects, features and advantages of the present invention will become more apparent by describing in more detail exemplary embodiments thereof with reference to the attached drawings, in which like reference numerals generally represent like parts throughout.

Fig. 1 shows a block diagram of a phototherapy apparatus according to an embodiment of the invention.

Fig. 2 shows a schematic structural diagram of a configured lounge chair of a phototherapy apparatus according to an embodiment of the invention.

Fig. 3 shows a box-type structural diagram of a phototherapy apparatus according to an embodiment of the invention.

Fig. 4 shows a graph comparing the red-near infrared LED emission spectrum and the cytochrome c oxidase absorption spectrum of a phototherapy apparatus according to an embodiment of the invention.

Fig. 5 shows a graph comparing the emission spectrum of a cyan LED of a phototherapy apparatus according to an embodiment of the invention with the melatonin secretion inhibition rate of a human subject as a function of wavelength.

Fig. 6 shows a orange LED emission spectrum of a phototherapy apparatus according to an embodiment of the invention.

Fig. 7 illustrates a full spectrum white light LED emission spectrum of a phototherapy device in accordance with an embodiment of the present invention.

Fig. 8 shows a schematic diagram of an arrangement of LED lamp panels inside a hood of a phototherapy apparatus according to an embodiment of the invention.

Fig. 9 is a schematic structural diagram of a red-near infrared LED lamp bead inside a hood of a phototherapy device according to an embodiment of the invention.

Fig. 10 is a schematic diagram illustrating an ear canal light guide of a phototherapy apparatus according to an embodiment of the invention.

Fig. 11 illustrates a schematic view of a nasal sinus of a phototherapy device in accordance with an embodiment of the present invention.

Fig. 12 illustrates an exploded view of an illuminator for directing light from the ear canal and sinus cavity of a nasal sinus of a phototherapy device in accordance with an embodiment of the invention.

Fig. 13 illustrates a pillow pocket of a phototherapy device having LEDs embedded to illuminate the Fengchi and Fengfu pockets, according to an embodiment of the invention.

Fig. 14 shows an overall circuit diagram of a phototherapy apparatus according to an embodiment of the invention.

Fig. 15 shows a circuit diagram of a wireless bluetooth controller of a phototherapy device according to an embodiment of the invention.

Drawings

1. A head cover; 2. a panel light; 3. a pillowcase; 4. an ear canal fiber; 5. nasal sinus optical fiber; 6. mood and psychiatric treatment lights; 7. an iPad intelligent terminal; 8. a monitoring device; 9. an oximeter; 10. a Bluetooth controller; 11. a light emitter; 12. an earplug; 13. a luminescent nose-hole device; 14. a light source; 15. a condenser lens; 16. an optical fiber holder.

Detailed Description

Preferred embodiments of the present invention will be described in more detail below. While the following describes preferred embodiments of the present invention, it should be understood that the present invention may be embodied in various forms and should not be limited by the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the invention to those skilled in the art.

The phototherapy device is used for treating Parkinson diseases and Alzheimer diseases and comprises a scalp phototherapy unit, an eye phototherapy unit, a nasal cavity and nasal sinus phototherapy unit, an ear canal phototherapy unit, a Fengchi and Fengfu hole phototherapy unit, a whole body phototherapy unit, an automatic controller and an intelligent terminal:

the scalp phototherapy unit is wrapped on the scalp of the patient and used for emitting a first path of light to the scalp of the patient, and the first path of light passes through the scalp of the patient and is transmitted to the brain;

the eye phototherapy unit is used for irradiating the eyes of the patient and emitting a second path of light to the eyes of the patient, and the second path of light is transmitted to the brain through the eyes of the patient;

the Fengchi and Fengfu phototherapy unit is arranged behind the brain of the patient and is used for emitting fifth light to the Fengchi and Fengfu acupuncture points of the patient, and the fifth light passes through the Fengchi and Fengfu acupuncture points of the patient and is transmitted to the brain;

the input end of the automatic controller is connected with the intelligent terminal and used for receiving a target phototherapy unit starting instruction, a target phototherapy unit emitting light source type instruction and a phototherapy duration instruction issued by the intelligent terminal, and the output end of the automatic controller is respectively connected with the scalp phototherapy unit, the eye phototherapy unit, the nasal cavity and paranasal sinus phototherapy unit, the ear canal phototherapy unit, the Fengchi point, the Fengfu point phototherapy unit and the whole body phototherapy unit and used for sending the target phototherapy unit starting instruction, the target phototherapy unit emitting light source type instruction and the phototherapy duration instruction to the target phototherapy unit, wherein the target phototherapy unit is at least one of the scalp phototherapy unit, the eye phototherapy unit, the nasal cavity and paranasal sinus phototherapy unit, the ear canal phototherapy unit, the Fengchi point, the Fengfu point phototherapy unit and the whole body phototherapy unit;

the first light, the second light, the third light, the fourth light and the fifth light are red light-near infrared light with the wavelength range of 600-1050nm; the sixth path of light comprises cyan light with the wavelength range of 400-600nm, orange light with the wavelength range of 500-750nm and white light with the wavelength range of 400-780 nm.

Specifically, the phototherapy device comprises a scalp phototherapy unit, an eye phototherapy unit, a nasal cavity, a nasal sinus and ear canal phototherapy unit, a Fengchi point and Fengfu point phototherapy unit, a whole body phototherapy unit, an automatic controller and an intelligent terminal, wherein the Fengchi point and Fengfu point phototherapy unit fully utilizes the traditional Chinese medicine achievement and combines the traditional Chinese medicine and the western medicine, and light is more effectively transmitted to the brain stem, the brain substantia nigra and the striatum. Meanwhile, the first path of light, the second path of light, the third path of light, the fourth path of light and the fifth path of light emitted by the phototherapy device are red light-near infrared light with the wavelength range of 600-1050nm; the sixth path of light is cyan light with the wavelength range of 400-600nm, orange light with the wavelength range of 500-750nm and white light with the wavelength range of 400-780 nm. Namely, the phototherapy device of the invention adopts red light-near infrared light in the range of 600-1050nm to irradiate the brain for brain treatment; the whole body is irradiated by cyan light with a wavelength range of 400-600nm, orange light with a wavelength range of 500-750nm and white light with a wavelength range of 400-780nm alternately according to the sequence of cyan light, white light and orange light, and the utility model is used for treating psychosis. Therefore, the phototherapy apparatus of the present invention can be used for a wider range of broadband spectrum treatments.

Furthermore, the PBM phototherapy devices reported in australia, france, usa, india and other countries at present mainly adopt 670nm narrow-band spectrum deep red light emitted by LED chips and 810nm, 850nm or other wavelengths of near-infrared light, and adopt discontinuous narrow-band spectrum red light-near-infrared light; the phototherapy device of the invention adopts a broad spectrum, and has better effect compared with the phototherapy device; the light absorption generated by the transition of electrons between different states of biological tissues is a broad band spectrum no matter the light receptor is cytochrome c oxidase in cell mitochondria, porphyrin light receptor in heme, or non-mitochondrial light receptor (such as reduced nicotinamide adenine dinucleotide phosphate oxidase, reduced coenzyme II); in cytochrome c oxidase, electrons are along the mitochondrial respiratory chain Cu _A -heme a- [ heme a3-CuB]-O ₂ Transfer of Cu therein _A Reduced state and Cu _A The peak values of the oxidation state absorption band are respectively 620nm and 820nm, and the peak values of the CuB reduction state absorption band and the CuB oxidation state absorption band are respectively 760nm and 680nm; electrons are transmitted along a respiratory chain in mitochondria, the dynamic equilibrium series process is the synergistic effect of photons with various wavelengths, and any link can influence the overall efficiency of electron transmission, so that the broadband spectrum is more effective than the narrow-band spectrum.

Furthermore, the phototherapy device of the present invention uses a non-invasive manner to transmit light to the brain, the present invention uses a broadband spectrum in the range of 600-1050nm, which includes not only the spectrum components capable of effectively activating cytochrome c oxidase, but also the spectrum components capable of activating the brain substantia nigra to secrete dopamine, so that the phototherapy device of the present invention is safer and more effective, and the first path of light, the second path of light, the third path of light, the fourth path of light and the fifth path of light are all red light-near infrared light in the wavelength range of 600-1050nm, which can be light covering the entire wavelength range of 600-1050nm, or light covering a section of the wavelength range of 600-1050nm, preferably light of 600-850 nm; the sixth path of light comprises cyan light with the wavelength range of 400-600nm, orange light with the wavelength range of 500-750nm and white light with the wavelength range of 400-780nm, and the green light, the white light and the orange light are alternately used according to the sequence of the cyan light, the white light and the orange light. .

Further, the phototherapy device of the invention has the functions of regulating and controlling the spirit and emotion of PD/AD patients; the invention not only adopts red light-near infrared light, but also adopts cyan, orange light and full spectrum white light in the visible light range; in the early stage of PD/AD patients, mainly adopt red light-near infrared light to carry on PBM treatment, but in the middle and late stage, once PD/AD patients appear affective and mental disorder, on the basis of adopting red light-near infrared light to treat, use cyan, orange light and full spectrum white light to treat; the red light-near infrared light provides nutrition for neurons, reduces oxidative stress injury, stimulates the growth of nerve touch cells, stimulates the secretion of neurotransmitter, regulates immunity through transcription factors, repairs damaged neurons, fundamentally protects the neurons, and delays and reduces the degeneration of the neurons; the electric shock therapy is a method widely adopted by psychologists for treating depression, but the symptoms of amnesia are easy to appear after electric shock; the invention adopts the alternate irradiation of cyan light with the peak wavelength of 480-490nm and orange light with the peak wavelength of 565-585nm, and the electric polarization and depolarization are generated in turn by the light stimulation neurons, so as to achieve the electric shock effect, which is beneficial to eliminating the depression symptom of PD/AD patients, and the non-invasive way is safer and more effective.

Further, the cyan spectrum contains 484nm, which is the most effective spectral component for inhibiting melatonin, and the spectral illumination is used in daytime to make people more exciting and more spiritual; the dark environment below 30 lux illumination is kept at night for sleep to promote melatonin secretion, and the sleep state of middle and late PD/AD patients is improved by alternate action, so that the mental state is improved. The red light-near infrared light component adopted by the invention can stimulate neurons to secrete nerve-delivered dopamine, so that people are happy.

Furthermore, the phototherapy device of the invention further comprises an external lamp, which is arranged outside the patient and used for starting when the patient has emotional and mental disorders, wherein the external lamp is provided with four lamp beads of red light, near infrared light, cyan light, orange light and full spectrum white light.

Further, the intelligent terminal is at least one of a smart phone, an IPAD, a computer and a wall node switch.

Further, for red light-near infrared light, the daily dose of light taken into human body is 10-80J/cm ² Can be divided into a plurality of times of intake; the light dose per irradiation from the head is not less than 5J/cm ² But not more than 30J/cm ² (ii) a The light dose irradiated from Feng Fu acupoint of wind pool is not less than 3J/cm ² But not more than 20J/cm ² (ii) a The light dose from eyes, nasal cavity, nasal sinuses and auditory canal is not less than 1J/cm ² But not more than 10J/cm ² . For middle and late PD/AD patients, the treatment of affective and mental disorders is only carried out after waking up in the morning, and the patients must be irradiated by red light-near infrared light before being irradiated by cyan light, and the illumination time of each light depends on the illumination intensity of the light source and the severity of the illness state of the patients according to the sequence of red light-near infrared light → cyan light → full spectrum → orange light → cyan light → full spectrum → orange light → full spectrum → orange light. The illumination of full spectrum white light is 5000-100000Lux, and the illumination of cyan light and orange light is 2500-10000Lux. The light dose of the cyan light and the orange light is calculated by the attending doctor according to the equal proportion of the spectrum integral intensity by taking the light energy corresponding to the illumination of the white light illumination intensity of 10000Lux for 30 minutes as the dosage standard of each day, and the light dose is properly increased or decreased according to the degree of the illness state of the patient.

Further, the control terminal is a smart phone, an IPAD, a computer or a wall node switch.

In one example, the scalp phototherapy unit comprises a first shell, a first lampshade, a first illumination module, a reflector and a blowing device, wherein the first shell is connected with the first lampshade to form a first cavity, and the first illumination module, the reflector and the blowing device are arranged in the first cavity; wherein the content of the first and second substances,

the first illumination module is used for emitting first path of light;

the reflector is used for reflecting the first path of light emitted by the first illumination module, irradiating the reflected light on the scalp of the patient through the first lampshade, and transmitting the reflected light to the brain through the scalp of the patient;

the blowing device is used to blow air to the scalp of the patient to increase the comfort of the patient.

Specifically, most of the light is transmitted to the cerebral cortex, hippocampus, and a small amount of light is transmitted to the substantia nigra and striatum after being attenuated.

Further, the blowing device is used for blowing air to the scalp of the patient to increase the comfort of the patient, blowing cold air in summer and blowing hot air in winter.

In one example, the eye phototherapy unit includes a second housing, a second lamp cover, and a second illumination module, the second housing is connected to the second lamp cover to form a second cavity, the second illumination module is disposed in the second cavity, and a second path of light emitted by the second illumination module irradiates the eyes of the patient through the second lamp cover and is transmitted to the brain through the eyes of the patient.

Specifically, the retina is a part with the highest mitochondrial density, is rich in dopamine neurons, is connected with the brain by the eyes, can transmit a small amount of light to the brain through a path connected with the brain by the eyes, and effectively activates the mitochondria and the dopamine neurons in the retina in the transmission process.

In one example, the nasal sinus phototherapy unit includes a third illumination module and a nasal sinus optical fiber, wherein the third illumination module is connected to the nasal sinus optical fiber, so that a third path of light emitted by the third illumination module is irradiated to the nasal sinus of the patient through the nasal sinus optical fiber and is transmitted to the brain through the nasal sinus of the patient;

the ear canal phototherapy unit comprises a fourth illumination module and an ear hole optical fiber, wherein the fourth illumination module is connected with the ear hole optical fiber, so that the fourth path of light emitted by the fourth illumination module irradiates the ear canal of the patient through the ear hole optical fiber and passes through the ear canal of the patient to be transmitted to the brain.

In one example, the wind pool and wind house phototherapy unit comprises a third shell, a third lampshade and a fifth lighting module, the third shell is connected with the third lampshade to form a third cavity, the fifth lighting module is arranged in the third cavity, and fifth light emitted by the fifth lighting module irradiates the wind pool and wind house of the patient through the third lampshade and is transmitted to the brain through the wind pool and wind house of the patient;

the whole body phototherapy unit comprises a fourth shell, a fourth lampshade and a sixth illumination module, the fourth shell is connected with the fourth lampshade to form a fourth cavity, the sixth illumination module is arranged in the fourth cavity, and sixth light emitted by the sixth illumination module irradiates the whole body of the patient through the fourth lampshade and passes through the skin and eyes of the patient to be transmitted to the brain.

In one example, the first illumination module comprises a first circuit board and a first LED lamp bead, the first LED lamp bead is disposed on the first circuit board, wherein the first LED lamp bead is configured to emit red light-near infrared light in a wavelength range of 600-1050nm;

the second illumination module comprises a second circuit board and a second LED lamp bead, and the second LED lamp bead is arranged on the second circuit board and used for emitting red light-near infrared light with the wavelength range of 600-1050nm;

the third illumination module comprises a third circuit board and a third LED lamp bead, and the third LED lamp bead is arranged on the third circuit board and used for emitting red light-near infrared light with the wavelength range of 600-1050nm;

the fourth illumination module comprises a fourth circuit board and a fourth LED lamp bead, and the fourth LED lamp bead is arranged on the fourth circuit board and used for emitting red light-near infrared light with the wavelength range of 600-1050nm;

the sixth illumination module comprises a sixth circuit board, a sixth LED lamp bead, a seventh LED lamp bead and an eighth LED lamp bead, wherein the sixth LED lamp bead, the seventh LED lamp bead and the eighth LED lamp bead are arranged on the sixth circuit board, the sixth LED lamp bead is used for emitting cyan light in a wavelength range of 400-600nm, the seventh LED lamp bead is used for emitting orange light in a wavelength range of 500-750nm, and the eighth LED lamp bead is used for emitting white light in a wavelength range of 400-780 nm.

Specifically, in practical application, when the panel lamp is manufactured, the circuit board is preferably a flexible lamp strip circuit substrate, and when the LED light source at the head cover type light source, the nose, the ears and the wind pool wind house cavity is manufactured, the circuit board is preferably a high-heat-conductivity aluminum-based PCB.

In one example, the phototherapy device further includes a smart sensing unit;

the first sensors are respectively arranged on the scalp phototherapy unit, the eye phototherapy unit, the nasal cavity and ear canal phototherapy unit, the acupuncture point phototherapy unit and the whole body phototherapy unit and are used for collecting the light dose of the emitted light source;

the plurality of second sensors are respectively arranged at the target part of the patient and are used for acquiring the physical health state information of the patient;

and the camera device is arranged outside the patient and used for acquiring the posture information of the patient.

Specifically, the first sensor is preferably a laser sensor and is used for controlling the light dose irradiated on the patient, the second sensor is preferably a laser sensor and is used for monitoring and analyzing the body health state information of the patient in real time, the camera device is preferably a camera and is used for collecting the posture information of the patient, and based on the light dose, the body health state information and the posture information, the data relation between the human skin surface offset delta and the imaging offset d is calculated by adopting an image recognition and posture algorithm, so that the tremor waveform is obtained to realize the detection of the diseased and characterized body tremor degree of the patient in PD/AD; three groups of motion paradigms of wrist turning, leg lifting and 10m reciprocating are designed, and 6 indexes of wrist turning frequency, wrist turning amplitude, leg lifting frequency, walking stride and turning time are quantitatively tested and analyzed.

Further, a plurality of second sensors are respectively arranged at the target part of the patient and are used for acquiring the physical health state information of the patient, including the tremor frequency and amplitude, the body temperature, the blood oxygen content and the heart rate of the patient in the PD/AD; the camera device is installed outside the patient and used for collecting posture information of the patient, and the posture information comprises wrist turning frequency, wrist turning amplitude, leg lifting frequency, walking step frequency, walking stride and turning time 6 indexes.

In one example, the phototherapy device further includes a central processor;

the input end of the central processing unit is connected with the intelligent sensing unit and used for receiving the light dose data uploaded by the intelligent sensing unit and the body health state information and posture information of the patient, and the output end of the central processing unit is connected with the intelligent terminal and used for transmitting the optimal light dose obtained through machine learning to the intelligent terminal for reference based on the light dose data and the body health state information and posture information of the patient.

In one example, the phototherapy device further includes a cloud;

the cloud end is connected with the central processing unit and the intelligent terminal respectively and used for storing a database required by machine learning and transmitting the optimal light dose of each patient to the intelligent terminal.

In one example, the automatic controller is a wireless bluetooth controller, and the wireless bluetooth controller comprises a power circuit, a bluetooth Mesh module U2, a first driving circuit, a second driving circuit and a third driving circuit;

the output end of the Bluetooth Mesh module U2 is respectively connected with the input ends of a first drive circuit, a second drive circuit and a third drive circuit, wherein,

the output end of the first driving circuit is respectively connected with the scalp phototherapy unit, the eye phototherapy unit, the nasal cavity and paranasal sinus phototherapy unit, the auditory canal phototherapy unit, the Fengchi and Fengfu phototherapy unit and the whole body phototherapy unit, and the first driving circuit is used for controlling the opening of the target phototherapy unit according to the instruction for starting the target phototherapy unit;

the output end of the second driving circuit is respectively connected with the scalp phototherapy unit, the eye phototherapy unit, the nasal cavity and nasal sinus phototherapy unit, the auditory canal phototherapy unit, the Fengchi and Fengfu acupoint phototherapy unit and the whole body phototherapy unit and used for controlling the closing of the target phototherapy unit according to phototherapy time length instructions;

the output end of the third driving circuit is respectively connected with the scalp phototherapy unit, the eye phototherapy unit, the nasal cavity and paranasal sinus phototherapy unit, the auditory canal phototherapy unit, the Fengchi and Fengfu acupoint phototherapy unit and the whole body phototherapy unit, and the third driving circuit is used for controlling the light dose of the light source emitted by the target phototherapy unit according to the type instruction of the light source emitted by the target phototherapy unit;

the power circuit is respectively connected with the Bluetooth Mesh module U2, the first driving circuit, the second driving circuit and the third driving circuit and used for supplying power to the Bluetooth Mesh module U2, the first driving circuit, the second driving circuit and the third driving circuit.

Specifically, the power supply circuit comprises a diode D1, a resistor R2, a resistor R3, a diode D2, a battery E2, a chip U1 and an electrolytic capacitor E1, wherein a cathode of the diode D1 is connected with an anode of an external power supply and one end of the resistor R1, an anode of the diode D1 is respectively connected with a cathode of the external power supply, a cathode of the electrolytic capacitor E2, a first pin of the chip U1 and a cathode of the electrolytic capacitor E1, the other end of the resistor R1 is connected with an anode of the diode D2 through the resistor R2 and the resistor R3, a cathode of the diode D2 is respectively connected with an anode of the electrolytic capacitor E2 and a second pin of the chip U1, and a third pin of the chip U1 and an anode of the battery E1 are connected and serve as a +10V power output interface. The model of the chip U1 is ME6203A.

Furthermore, the first driving circuit, the second driving circuit and the third driving circuit have the same structure, the PWM control input end of the first driving circuit is connected with the third pin of the bluetooth Mesh module U2, the PWM control input end of the second driving circuit is connected with the fourth pin of the bluetooth Mesh module U2, and the PWM control input end of the third driving circuit is connected with the fifth pin of the bluetooth Mesh module U2.

Further, the wireless Bluetooth controller controls the illumination module, specifically, independent constant current driving is performed on the LED arrays in the illumination module, and meanwhile, PWM signals are transmitted to each LED array; the control terminal is used for setting phototherapy parameters for a user, wherein the phototherapy parameters comprise parameters such as peak wavelength, duty ratio, frequency and working time, and the set parameters are transmitted to the PWM dimming control circuit through the Bluetooth mesh chip; the signal sent by the PWM dimming control circuit is transmitted to the LED array on the lighting module through the electric path of the circuit substrate again, so that the LED array sends pulse light with specific working time, specific peak wavelength, specific duty ratio and specific frequency.

Furthermore, the input voltage range of the wireless Bluetooth controller is 5-12 Vdc, the working voltage range is 3.3dc100mA, the working frequency range is 2.404-2.480 GHz, the maximum data transmission rate is 1Mbits/s, and the maximum data transmission distance range of the two nodes is 10-30M.

Furthermore, the intelligent terminal is connected with the wireless Bluetooth controller and used for optimizing an optical path output by the LED array so as to generate the optimal treatment effect and setting the pulse light wavelength, the pulse light power and the illumination action time.

In one example, the phototherapy device further comprises a driving power supply, wherein the driving power supply is used for supplying power to the LED light source and the intelligent terminal;

specifically, by configuring the mobile power supply, the mobile power supply can work under the condition of switching on and switching off the mains supply.

A phototherapy method utilizing the phototherapy apparatus, comprising:

for patients with intermediate and advanced parkinson's disease and alzheimer's disease, phototherapy is applied to the patients by at least one of the first to fifth optical paths; and

phototherapy is applied to the patient using a sixth light path to treat the patient for affective and psychiatric disorders.

Example 1

As shown in fig. 1, a phototherapy device for the treatment of parkinson's disease and alzheimer's disease comprises a scalp phototherapy unit, an eye phototherapy unit, a nasal cavity and paranasal sinus phototherapy unit, an ear canal phototherapy unit, a Fengchi and Fengfu phototherapy unit, a whole body phototherapy unit, an automatic controller and an intelligent terminal:

the ear canal phototherapy unit is arranged outside the patient and is used for emitting fourth light to the ear canal of the patient, and the fourth light passes through the ear canal of the patient and is transmitted to the brain;

the whole body phototherapy unit is arranged outside the patient and used for emitting sixth light to the whole body of the patient, and the sixth light passes through the skin and eyes of the patient and is transmitted to the brain;

the input end of automatic controller is connected with intelligent terminal, be used for receiving the start target phototherapy unit instruction that intelligent terminal assigned, target phototherapy unit transmission light source type instruction and the long instruction of time of phototherapy, the output respectively with scalp phototherapy unit, eyes phototherapy unit, nasal cavity and paranasal sinus phototherapy unit, ear canal phototherapy unit, fengchi cave is connected with Fengfu cave phototherapy unit and whole body phototherapy unit, be used for starting target phototherapy unit instruction, target phototherapy unit transmission light source type instruction and the long instruction of time of phototherapy are sent to target phototherapy unit, wherein, target phototherapy unit is scalp phototherapy unit, eyes phototherapy unit, nasal cavity and paranasal sinus phototherapy unit, ear canal phototherapy unit, fengchi cave and at least one in Fengfu cave phototherapy unit and whole body phototherapy unit.

The specific implementation mode is as follows:

as shown in figure 2, the patient can choose lying or sitting for photo-biological treatment, the phototherapy device is provided with a head cover 1 embedded with an LED light source, a panel light 2, a nasal cavity and paranasal sinus optical fiber 5 introduced into nasal cavity and paranasal sinus, an ear canal optical fiber 4 introduced into ear canal, a pillow case 3 embedded with an LED light source and capable of irradiating Fengchi and Fengfu, an emotion and psychotherapy light 6 for treating mental diseases, and is provided with an iPad intelligent terminal 7, a monitoring device 8 and an oximeter 9.

Example 2

the input end of the automatic controller is connected with the intelligent terminal, and is used for receiving a target phototherapy unit starting instruction given by the intelligent terminal, the target phototherapy unit emits a light source type instruction and a phototherapy duration instruction, and the output end of the automatic controller is respectively connected with the scalp phototherapy unit, the eye phototherapy unit, the nasal cavity and paranasal sinus phototherapy unit, the ear canal phototherapy unit, the Fengchi hole, the Fengfu hole phototherapy unit and the whole body phototherapy unit, and is used for sending the target phototherapy unit starting instruction, the target phototherapy unit emits the light source type instruction and the phototherapy duration instruction to the target phototherapy unit, wherein the target phototherapy unit is at least one of the scalp phototherapy unit, the eye phototherapy unit, the nasal cavity and paranasal sinus phototherapy unit, the ear canal phototherapy unit, the Fengchi hole, the Fengfu hole and the Fengfu hole phototherapy unit and the whole body phototherapy unit.

The specific implementation mode is as follows:

as shown in fig. 3, the head cover 1 and the panel light 2 are arranged outside the box body and are provided with an iPad intelligent terminal 7; the nasal cavity and paranasal sinus optical fiber (not shown), the ear canal optical fiber (not shown), the pillow case 3 for irradiating the Fengchi and Fengfu cavities, the sensing and detecting device (not shown) and the tablet personal computer (not shown) are contained in the box body, taken out when in use and put in the box body when not in use. The device design characteristics are pleasing to the eye, portable, make things convenient for nurse or patient's family members to remove the device to ward or patient sick bed limit and treat. No chair is arranged in the shell, and a patient can lie on a bed, a sofa or a household table and chair during treatment. A light source in the hood 1 is provided with red light-near infrared light LED lamp beads; the panel light 2 can be simultaneously provided with four types of LED lamp beads of red light, near infrared light, cyan light, orange light and full-spectrum white light, and each type of LED lamp bead can also be independently made into a lamp. The light which is led into the paranasal sinuses, the auditory meatus, the eyes and the Fengchi acupoint is red light-near infrared light; cyan, orange and full spectrum white light adopt a diffuse reflection mode or a skin irradiation mode.

Example 3

the eye phototherapy unit is irradiated on the eyes of the patient and used for emitting second path light to the eyes of the patient, and the second path light passes through the eyes of the patient to be transmitted to the brain;

The scalp phototherapy unit comprises a first shell, a first lampshade, a first illumination module, a reflector and a blowing device, wherein the first shell is connected with the first lampshade to form a first cavity; wherein the content of the first and second substances,

the first illumination module is used for emitting first path of light;

The eye phototherapy unit comprises a second shell, a second lampshade and a second illumination module, the second shell is connected with the second lampshade to form a second cavity, the second illumination module is arranged in the second cavity, and second path of light emitted by the second illumination module irradiates the eyes of the patient through the second lampshade and is transmitted to the brain through the eyes of the patient.

The nasal cavity and paranasal sinus phototherapy unit comprises a third illumination module and a nasal cavity and paranasal sinus optical fiber, wherein the third illumination module is connected with the nasal cavity and paranasal sinus optical fiber, so that third path light emitted by the third illumination module irradiates the nasal cavity and paranasal sinus of a patient through the nasal cavity and paranasal sinus optical fiber and passes through the nasal cavity and paranasal sinus of the patient to be transmitted to the brain;

The fifth illumination module is arranged in the third cavity, and fifth path of light emitted by the fifth illumination module irradiates the wind pool and wind house cavities of the patient through the third lamp shade and passes through the wind pool and wind house cavities of the patient to be transmitted to the brain;

The specific implementation mode is as follows:

the first illumination module, the second illumination module, the third illumination module and the fourth illumination module are composed of LED lamp beads, a radiating fin and a constant-current driving power supply, the LED lamp beads emit red light-near infrared light sources, the emission wavelength range of the LED lamp beads is 600-1050nm, the emission wavelength range of the LED lamp beads can be one section of the red light-near infrared light sources, and can also be continuous light covering the 600-1050nm range, the LED lamp beads of the embodiment adopt GdAl ₃ (BO ₄ ):Cr、MgGa ₂ O ₄ :Cr、LiScSi ₂ O ₆ Cr and CaAlSiN ₃ Eu multiple fluorescent powder is packaged together with a blue light chip, and the emission spectrum of the Eu multiple fluorescent powder covers 600-1050nm; as shown in fig. 4, the black line in the graph is a light source spectrum, the dotted line is a cytochrome c oxidase activity spectrum actually measured according to the DNA synthesis rate of HeLa cells, and the dotted line is cytochrome c oxidase fitted with a gaussian function, and it can be found by comparing the absorption spectrum of cytochrome c oxidase that the emitted light can effectively activate the reactivity of cytochrome c oxidase in the mitochondria of cells; in addition, the spectrum can activate dopamine neurons to secrete the neurotransmitter dopamine.

Example 4

The phototherapy device structure of the embodiment is the same as the phototherapy device structure of the embodiment 3, and is used for treating mental disorder of middle and late PD and AD patients, wherein the LED lamp beads emit cyan light, the cyan light emission wavelength range is 400-600nm, and the emission wavelength peak value is 480-495nm; the green LED lamp bead adopts near ultraviolet and blue light double chips and is coated with Sr ₃ MgSiO ₈ Eu blue phosphor and Ba ₂ SiO ₄ Eu green phosphor powder is packaged; in practical research, the most effective wavelength for suppressing melatonin secretion is 484nm, as can be seen from fig. 5, the black line in the graph is a light source spectrum, the dot-dash line is the actually measured variation of melatonin suppression rate with wavelength, the dotted line is the fitted variation of melatonin suppression rate with wavelength, and the comparison of the emission spectrum of the cyan LED and the variation of the melatonin suppression rate with wavelength of a human body can find that the first LED bead and the second LED bead of the cyan light are different from each otherThe two LED lamp beads, the third LED lamp bead and the fourth LED lamp bead can effectively inhibit melatonin secretion, sleepiness can be eliminated by using the spectrum illumination, the mental state of a person in the daytime is improved, and the emission spectrum of the LED with cyan light in the figure 5 is just 490nm, so that the neuron generates charges to generate electric polarization by using the light source illumination.

Example 5

The phototherapy apparatus of this embodiment has the same structure as the phototherapy apparatus of embodiment 3, and is used for treating mental disorder of PD and AD patients in middle and late stages, wherein the orange light emission wavelength range is 500-750nm, the emission wavelength peak is 569-589nm, and the peak wavelength is 579nm is the best; the LED lamp bead with orange light adopts a blue light chip matched with Sr ₃ SiO ₅ Eu fluorescent powder is packaged, as shown in figure 6, the peak value of the emission spectrum of an orange light LED lamp bead is 580nm, and in practical research, the optimal wavelength for depolarization of neurons is 579nm. Therefore, the light is used for treating depression symptoms of middle and late PD/AD patients to achieve electric shock effect without damage.

Example 6

The phototherapy device structure of this embodiment is the same as the phototherapy device structure of embodiment 3, and is used for treating mental disorder of PD and AD middle and late stage patients, wherein the LED lamp beads emit white light with a wavelength range of 400-780nm, and white light with a color temperature higher than 5500K must not be used to avoid damage to neurons; in order to keep people alive and eliminate drowsiness, it is not recommended to use warm color light having a color temperature lower than 3500K. FIG. 7 shows one of the spectra of a representative full spectrum white light source, covering the range of 400-780nm, with color temperatures of 3500-5500K, and most preferably 4000K.

Example 7

As shown in fig. 1, a phototherapy device for the treatment of parkinson's disease and alzheimer's disease comprises a scalp phototherapy unit, an eye phototherapy unit, a nasal cavity and nasal sinus phototherapy unit, an ear canal phototherapy unit, a Fengchi and Fengfu phototherapy unit, a whole body phototherapy unit, an automatic controller and an intelligent terminal:

the scalp phototherapy unit is wrapped on the scalp of the patient and used for emitting first light to the scalp of the patient, and the first light is transmitted to the brain through the scalp of the patient;

The hood for the PBM treatment of the PD/AD patient adopts a direct illumination mode, a reflecting film is arranged in the hood for enhancing light emission, and the hood can blow cold and hot breeze, so that the patient can enjoy comfortable treatment all the year round; as shown in FIGS. 8-9, the diameter of the lamp panel is 22-26cm, and the light emergent surface can cover the whole head partThe optical power is 0-200mW/cm ² The range is continuously adjustable.

Specifically, fig. 10 to 11 show schematic diagrams of a light emitting device for guiding light to the brain through the ear canal and the nasal sinuses, the device comprises a light emitter 11, a bluetooth controller 10, a nasal sinus optical fiber 5 or an ear hole optical fiber 4, an earplug 12 or a light emitting nostril 13; further decomposing the structure of the light emitter, as shown in fig. 12, including the LED heat dissipation and light emission light source 14, the condensing lens 15 and the optical fiber holder 16; the optical fiber and the LED device can also be directly bonded by using silica gel without using a condenser lens.

The fourth illumination module for illuminating the Fengchi and Fengfu acupoints may be installed in the treatment device shown in fig. 2, or the fourth illumination module may be moved into the pillow case, and an independent power supply and a controller are disposed in the pillow case, so that the pillow case can be conveniently worn around the neck and used in a portable manner, as shown in fig. 13.

Example 8

In a specific embodiment, an overall circuit diagram of the phototherapy apparatus of the present invention is shown in fig. 14, and an LED pulse light source with a certain frequency and duty ratio is obtained by a PWM dimming method, and the instantaneous energy of the LED pulse light source can be set to a higher state. The wireless controller connected with the intelligent terminal is connected with a circuit as shown in fig. 15, the wireless Bluetooth controller is input to a switching power supply through a 220V power supply, outputs 24V direct-current voltage to be provided for a Bluetooth Mesh module control system, and outputs the voltage to a simulation regulation load to realize two paths of PWM control output so as to ensure firmness, reliability, light volume and good heat dissipation of a product. The design adopts an aluminum extrusion profile natural color oxidation shell, and the input and output adopt a grid type wiring terminal (capable of directly pressing 4 square wires) with the diameter of P =9.50 mm. The input adopts wide voltage input (5-36 Vdc), which reaches 10A heavy current output and can be compatible with different products for use. The input adopts conventional wide voltage of 100-240V 50/60Hz, the output is 24V waterproof power supply, and the maximum power is 360W. After signals are input, the SS36 Schottky diode is reversely connected between positive and negative to perform input positive and negative reverse connection protection, after the input voltage is reduced and divided by the resistor, the voltage is output by the ME6203A low dropout linear voltage regulator at constant voltage and 10V voltage is supplied to the Bluetooth MESH module for supplying power, and meanwhile, the N-MOSFET driving circuit is supplied with power. : and the load among L + and L1-, L2-and L3-forms a loop on the negative electrode of the power supply through the control of the corresponding N-MOSFETs M1, M2 and M3, and performs control such as opening, closing, dimming, toning and the like.

The sensor detection module integrates a camera, a nine-axis sensor and a laser sensor, and calculates the data relation between the human skin surface offset delta and the imaging offset d by adopting an image recognition and posture algorithm to obtain a tremor waveform so as to realize the detection of the tremor degree of the sick and characteristic body of the patient in PD/AD; and three groups of motion paradigms of wrist turning, leg lifting and 10m reciprocating are designed, and 6 indexes of wrist turning frequency, wrist turning amplitude, leg lifting frequency, walking pace frequency, walking stride, turning time and the like are quantitatively tested and analyzed. Data collected by the sensor and the detector are automatically transmitted to the central processing unit, developed system software automatically analyzes the data, all data are contributed by the cloud, and a main doctor can retrieve the data at any time and any place, and a treatment scheme is formulated and implemented remotely.

Example 9

The invention also provides a phototherapy method, which utilizes the phototherapy equipment and comprises the following steps:

phototherapy a patient having intermediate and advanced parkinson's disease and alzheimer's disease using at least one of the first to fifth light paths; and

Specifically, for the first light path, the light dose range of each time the human body is ingested is 5J/cm ² ～30J/cm ² ；

For the second light path, the light dose range of each time the human body is ingested is 1J/cm ² ～10J/cm ² ；

For the third light path, the light dose range of each time the human body is ingested is 1J/cm ² ～10J/cm ² ；

For the fourth light path, the light dose range of each time the human body is ingested is 1J/cm ² ～10J/cm ² ；

For the fifth light path, the light dose range of each time the human body is ingested is 3J/cm ² ～20J/cm ² ；

For the first to fifth light paths, the daily intake of red-near infrared light energy into the human body is 10-80J/cm ² It can be divided into several times of intake.

The specific implementation mode is as follows:

after the patient wakes up in the morning, the red light-near infrared light is turned on, the illumination intensity of the red light-near infrared light in the solar spectrum corresponding to the full-spectrum white light of 10000lx is increased from 0 within 5 minutes through software setting, the illumination intensity is maintained for 10 minutes, and then the cyan light illumination is automatically switched. This 15 minute red-near infrared illumination was used to protect neurons from high intensity visible light causing neuronal damage. The mood and mental treatments were then performed as follows: cyan light 6 minutes → full spectrum white light 10 minutes → orange light 2 minutes → cyan light 6 minutes → full spectrum white light 10 minutes → orange light 2 minutes, 54 minutes complete treatment.

After the patient finishes washing, the red light-near infrared light treatment can be started after the patient finishes breakfast. The light dose of each time from the eye, nasal sinuses and auditory canals is 3J/cm ² (the optical fiber light spot is 1cm in length ² Calculation), the light dose is 6J/cm irradiated from the Feng Fu acupoint position of the wind pool ² From the head, a light dose of 10J/cm was irradiated ² (ii) a Red-near infrared light therapy is divided into 2 times per day, once in the morning, once in the afternoon or evening, and the total input light dose is 50J/cm per day ² . The emission spectra of the red-near infrared light, cyan light, orange light and full spectrum white light LED lamp beads used in this embodiment are shown in fig. 4, 5, 6 and 7, respectively. If the PD/AD patient does not present a psychiatric disorder, the first mood and psychiatric treatment step is not performed.

Furthermore, the sixth light path is only used in the morning hours (the sunny days) after the patient wakes up in the morning, and is forbidden in the afternoon hours and at night;

before the sixth light path of the opener, the first or the second light path is required to be received;

the 3 lights in the sixth light path are sequentially and alternately illuminated according to the sequence of the cyan light → the full spectrum → the orange light → the cyan light → the full spectrum → the orange light;

the illumination of the full spectrum white light in the sixth light path is 5000-100000Lux, and the illumination of the cyan light and the orange light is 2500-10000Lux.

In the sixth light path, the light energy corresponding to the full-spectrum white light illumination intensity of 10000Lux for 30 minutes is used as the daily dose reference, the light doses of the cyan light and the orange light are calculated in proportion according to the spectrum integral intensity, the illumination time of each light depends on the light source illumination intensity and the severity of the patient condition, and the light dose can be appropriately increased or decreased according to the severity of the patient condition.

Having described embodiments of the present invention, the foregoing description is intended to be exemplary, not exhaustive, and not limited to the embodiments disclosed. Many modifications and variations will be apparent to those of ordinary skill in the art without departing from the scope and spirit of the described embodiments.

Claims

1. A phototherapy device for treatment of Parkinson's disease and Alzheimer's disease, comprising a scalp phototherapy unit, an eye phototherapy unit, a nasal cavity and paranasal sinus phototherapy unit, an ear canal phototherapy unit, fengchi and Fengfu phototherapy units, a whole body phototherapy unit, an automatic controller and an intelligent terminal:

2. The phototherapy device as claimed in claim 1, wherein the scalp phototherapy unit comprises a first housing, a first lampshade, a first lighting module, a reflector plate and a blower, the first housing is connected with the first lampshade to form a first cavity, and the first lighting module, the reflector plate and the blower are disposed in the first cavity; wherein the content of the first and second substances,

the first illumination module is used for emitting the first path of light;

3. The phototherapy device of claim 2, wherein the eye phototherapy unit comprises a second housing, a second lamp shade, and a second illumination module, the second housing is connected to the second lamp shade to form a second cavity, the second illumination module is disposed in the second cavity, and the second path of light emitted by the second illumination module is irradiated to the patient's eyes through the second lamp shade and transmitted to the brain through the patient's eyes.

4. The phototherapy apparatus as claimed in claim 3, wherein the nasal sinus phototherapy unit comprises a third illumination module and a nasal sinus optical fiber, the third illumination module is connected to the nasal sinus optical fiber, so that the third path of light emitted by the third illumination module is irradiated to the nasal sinus of the patient through the nasal sinus optical fiber and is transmitted to the brain through the nasal sinus of the patient;

the ear canal phototherapy unit comprises a fourth illumination module and an ear hole optical fiber, wherein the fourth illumination module is connected with the ear hole optical fiber, so that the fourth path of light emitted by the fourth illumination module is irradiated to the ear canal of the patient through the ear hole optical fiber and passes through the ear canal of the patient to be transmitted to the brain.

5. The phototherapy device as claimed in claim 4, wherein the Fengchi-Fengfu phototherapy unit comprises a third housing, a third lamp cover and a fifth lighting module, the third housing is connected to the third lamp cover to form a third cavity, the fifth lighting module is disposed in the third cavity, and the fifth light emitted by the fifth lighting module is emitted to the Fengchi-Fengfu cavity and the Fengfu cavity of the patient through the third lamp cover and is transmitted to the brain through the Fengchi-Fengfu cavity and the Fengfu cavity of the patient;

6. The phototherapy device of claim 5, wherein the first illumination module comprises a first circuit board and a first LED lamp bead disposed on the first circuit board, wherein the first LED lamp bead is configured to emit red-near infrared light in the 600-1050nm wavelength range;

the second illumination module comprises a second circuit board and a second LED lamp bead, the second LED lamp bead is arranged on the second circuit board, and the second LED lamp bead is used for emitting the red light-near infrared light with the wavelength range of 600-1050nm;

7. The phototherapy device of claim 1, further comprising a smart sensing unit;

8. The phototherapy device of claim 7, further comprising a central processor;

9. The phototherapy device of claim 8, further comprising a cloud end;

10. The phototherapy device of claim 1, wherein the automatic controller is a wireless bluetooth controller comprising a power circuit, a bluetooth Mesh module U2, a first drive circuit, a second drive circuit, and a third drive circuit;

the input end of the Bluetooth Mesh module U2 is in communication connection with the intelligent terminal and is used for receiving the target phototherapy unit starting instruction, the target phototherapy unit emitting light source type instruction and the phototherapy duration instruction issued by the intelligent terminal;

the output end of the third driving circuit is respectively connected with the scalp phototherapy unit, the eye phototherapy unit, the nasal cavity and nasal sinus phototherapy unit, the ear canal phototherapy unit, the Fengchi and Fengfu acupoint phototherapy unit and the whole body phototherapy unit, and the third driving circuit is used for controlling the light dose of the light source emitted by the target phototherapy unit according to the type instruction of the light source emitted by the target phototherapy unit;

11. A phototherapy method using the phototherapy apparatus according to any one of claims 1-10, comprising: