CN115212163A - 一种天然草本茶含片及其制备方法 - Google Patents
一种天然草本茶含片及其制备方法 Download PDFInfo
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- CN115212163A CN115212163A CN202210697684.XA CN202210697684A CN115212163A CN 115212163 A CN115212163 A CN 115212163A CN 202210697684 A CN202210697684 A CN 202210697684A CN 115212163 A CN115212163 A CN 115212163A
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Abstract
本发明涉及含茶制品技术领域，具体是公开了一种天然草本茶含片，按照重量百分比包括以下组分：木糖醇20‑38％、绿茶3‑6％、海藻酸盐15‑30％、壳寡糖3‑5％、复合益生菌3‑20％、草本组合物8‑20％以及辅料8‑16％。所述复合益生菌包括植物乳杆菌、鼠李糖乳杆菌和沼泽红假单胞菌，且植物乳杆菌、鼠李糖乳杆菌和沼泽红假单胞菌的重量比为1：(2‑3)：(1‑5)。所述草本组合物按照重量百分比包括薄荷2‑16％、桔梗6‑8％、百合3‑8％、鱼腥草4‑10％、生姜3‑12％、甘草5‑10％、罗汉果4‑8％、胖大海4‑10％、葛根5‑15％、黄芩1‑5％、五倍子2‑8％、乳香3‑9％和香芹2‑8％。本发明克服了现有技术的不足，利用天然草本元素配合益生菌对口腔进行清洁，清除口臭、抑制细菌滋生，保护牙齿和牙龈。
Description
技术领域
本发明涉及含茶制品技术领域，具体属于一种天然草本茶含片及其制备方法。
背景技术
吸烟对人体的危害极大，烟草中的焦油利于细菌在牙面的附着，导致菌斑堆积，牙石、软垢增多，易造成烟黄牙、烟黑牙、牙龈炎和牙周炎，烟草中的尼古丁进入血液，导致牙龈血管收缩，血流减少，导致牙龈清除废物和保护修复功能降低，长期处于慢性炎症状态，而且吸烟者浓重的口腔烟臭味严重影响社交。
目前临床上多通过洗牙来去除牙齿表面的烟垢，达到洁牙的目的，但是洗牙会造成牙齿变薄、粗糙，之后更容易变黄和变黑，长远看来，会对牙齿造成不可逆的损伤。市场上也没有针对此类问题的专业产品。
发明内容
本发明的目的是提供了一种天然草本茶含片及其制备方法，克服了现有技术的不足，利用天然草本元素配合益生菌对口腔进行清洁，清除口臭、抑制细菌滋生，保护牙齿和牙龈。
为解决上述问题，本发明所采取的技术方案如下：
一种天然草本茶含片，按照重量百分比包括以下组分：木糖醇20-38％、绿茶3-6％、海藻酸盐15-30％、壳寡糖3-5％、复合益生菌3-20％、草本组合物8-20％以及辅料8-16％。
进一步，所述复合益生菌包括植物乳杆菌、鼠李糖乳杆菌和沼泽红假单胞菌，且植物乳杆菌、鼠李糖乳杆菌和沼泽红假单胞菌的重量比为1：(2-3)：(1-5)。
进一步，基于所述复合益生菌组合物的总重量，所述复合益生菌组合物中各菌株的活菌数分别为：植物乳杆菌4000-8000亿CFU/g；鼠李糖乳杆菌4000-5000亿CFU/g；副干酪乳杆菌1000-3000亿CFU/g。
进一步，所述草本组合物按照重量百分比包括薄荷2-16％、桔梗6-8％、百合3-8％、鱼腥草4-10％、生姜3-12％、甘草5-10％、罗汉果4-8％、胖大海4-10％、葛根5-15％、黄芩1-5％、五倍子2-8％、乳香3-9％和香芹2-8％。
进一步，所述草本组合物的各个组分采用植物有效部位，包括根、茎、叶、花和/或果实。
进一步，所述海藻酸盐采用海藻酸钠、海藻酸钾中的一种或者两种的组合物。
进一步，所述辅料由甘草甜素、罗勒粉末香精、乳糖和麦芽糊精按照1:3:20:10的质量比混合而成。
进一步，所述辅料的制备方法为：将甘草甜素、罗勒粉末香精采用等量递增法与乳糖和麦芽糊精配研混合后，再继续混合12-15min，得到辅料。
本发明还保护了一种天然草本茶含片的制备方法，包括如下步骤：
步骤一、按照上述重量百分数分别称取原料；
步骤二、取绿茶清洗干净，摊凉，蒸汽杀青，揉捻后微波干燥，多次粉碎、风选后得到粒径小于10um超微绿茶粉；
步骤三、取草本组合物，清洗干净、烘干后经水提醇沉获得提取浸液，将过滤后的提取液输送到提取液浓缩罐中进行浓缩，静置蒸发水分得到浸膏，将浸膏粉碎、过筛备用；
步骤四、将超微绿茶粉、草本组合物、木糖醇、海藻酸盐、壳寡糖、和辅料一起混合研磨后加入复合益生菌，通过模切的方法形成含片。
本发明与现有技术相比较，本发明的实施效果如下：
1、本发明利用天然草本元素配合益生菌对口腔进行清洁，清除口臭、抑制细菌滋生，保护牙齿和牙龈，无副作用。
2、本发明所采用的复合益生菌对口腔微生态环境有调节作用，抑制口腔内细菌的滋生，并减少病菌的黏附，深度清除口气。
3、本发明采用壳寡糖分子在酸性条件下游离氨基质子化，质子化按能与细菌带正电的细胞膜作用，干扰细菌细胞膜功能，造成细菌体内细胞质流失，对真菌和微生物的生长有抑制作用。
具体实施方式
下面结合实施例对本发明作进一步的描述，但本发明不仅限于这些实例，在为脱离本发明宗旨的前提下，所为任何改进均落在本发明的保护范围之内。
实施例1
本实施例公开了一种天然草本茶含片的制备方法，包括如下步骤：
步骤一、分别称取木糖醇20％、绿茶6％、海藻酸盐30％、壳寡糖3％、复合益生菌20％、草本组合物8％以及辅料13％。
其中，复合益生菌包括植物乳杆菌、鼠李糖乳杆菌和沼泽红假单胞菌，且植物乳杆菌、鼠李糖乳杆菌和沼泽红假单胞菌的重量比为1：2：1；复合益生菌组合物中各菌株的活菌数分别为：植物乳杆菌4000-8000亿CFU/g；鼠李糖乳杆菌4000-5000亿CFU/g；副干酪乳杆菌1000-3000亿CFU/g。
草本组合物按照重量百分比包括薄荷16％、桔梗6％、百合3％、鱼腥草4％、生姜12％、甘草10％、罗汉果8％、胖大海10％、葛根15％、黄芩1％、五倍子8％、乳香3％和香芹4％；草本组合物的各个组分采用植物有效部位，包括根、茎、叶、花和/或果实。
海藻酸盐采用海藻酸钠、海藻酸钾中的一种或者两种的组合物；
步骤二、辅料由甘草甜素、罗勒粉末香精、乳糖和麦芽糊精按照1:3:20:10的质量比混合而成；具体的，将甘草甜素、罗勒粉末香精采用等量递增法与乳糖和麦芽糊精配研混合后，再继续混合12-15min，得到辅料。
步骤三、取绿茶清洗干净，摊凉，蒸汽杀青，揉捻后微波干燥，多次粉碎、风选后得到粒径小于10um超微绿茶粉。
步骤四、取草本组合物，清洗干净、烘干后经水提醇沉获得提取浸液，将过滤后的提取液输送到提取液浓缩罐中进行浓缩，静置蒸发水分得到浸膏，将浸膏粉碎、过筛备用。
步骤五、将超微绿茶粉、草本组合物、木糖醇、海藻酸盐、壳寡糖、和辅料一起混合研磨后加入复合益生菌，通过模切的方法形成含片。
实施例2
本实施例所采用的制备方法与实施例1基本一致，唯有区别的是：含片按照重量百分比包括以下组分：木糖醇38％、绿茶3％、海藻酸盐15％、壳寡糖5％、复合益生菌3％、草本组合物20％以及辅料16％。
实施例3
本实施例所采用的制备方法与实施例1基本一致，唯有区别的是：植物乳杆菌、鼠李糖乳杆菌和沼泽红假单胞菌的重量比为1：3：5。
实施例4
本实施例所采用的制备方法与实施例1基本一致，唯有区别的是：草本组合物按照重量百分比包括薄荷10％、桔梗8％、百合8％、鱼腥草10％、生姜12％、甘草5％、罗汉果8％、胖大海4％、葛根5％、黄芩5％、五倍子8％、乳香9％和香芹8％。
实施例5
本实施例所采用的制备方法与实施例1基本一致，唯有区别的是：草本组合物按照重量百分比包括薄荷2％、桔梗8％、百合8％、鱼腥草6％、生姜3％、甘草10％、罗汉果4％、胖大海10％、葛根15％、黄芩5％、五倍子8％、乳香9％和香芹2％。
试验例
随机选择症状相当的吸烟者600例，选择的标准是：符合西医诊断标准和中医辩证标准、年龄在18-55岁之间，随机将上述病例分成6组，每组100人。
1-5组分别使用实施例1-5所制备的含片，6组使用市场上采购的某品牌口气清新漱口水，每天使用三次，持续1个月后分别统计烟臭味去除率、牙龈炎治愈率和牙齿美白率，具体结构见表1。
表1结果统计表
根据表1统计的结果可以看出，本发明所制备的含片针对口臭、牙龈炎具有显著的功效，可以有效改善口腔的清洁度，满足抽烟者的口腔清洁需要。
以上内容仅仅是对本发明构思所作的举例和说明，所属本技术领域的技术人员对所描述的具体实施例做各种各样的修改或补充或采用类似的方式替代，只要不偏离发明的构思或者超越本权利要求书所定义的范围，均应属于本发明的保护范围。
Claims (9)
1.一种天然草本茶含片，其特征在于：按照重量百分比包括以下组分：木糖醇20-38％、绿茶3-6％、海藻酸盐15-30％、壳寡糖3-5％、复合益生菌3-20％、草本组合物8-20％以及辅料8-16％。
2.根据权利要求1所述的一种天然草本茶含片，其特征在于：所述复合益生菌包括植物乳杆菌、鼠李糖乳杆菌和沼泽红假单胞菌，且植物乳杆菌、鼠李糖乳杆菌和沼泽红假单胞菌的重量比为1：(2-3)：(1-5)。
3.根据权利要求2所述的一种天然草本茶含片，其特征在于：基于所述复合益生菌组合物的总重量，所述复合益生菌组合物中各菌株的活菌数分别为：植物乳杆菌4000-8000亿CFU/g；鼠李糖乳杆菌4000-5000亿CFU/g；副干酪乳杆菌1000-3000亿CFU/g。
4.根据权利要求1所述的一种天然草本茶含片，其特征在于：所述草本组合物按照重量百分比包括薄荷2-16％、桔梗6-8％、百合3-8％、鱼腥草4-10％、生姜3-12％、甘草5-10％、罗汉果4-8％、胖大海4-10％、葛根5-15％、黄芩1-5％、五倍子2-8％、乳香3-9％和香芹2-8％。
5.根据权利要求4所述的一种天然草本茶含片，其特征在于：所述草本组合物的各个组分采用植物有效部位，包括根、茎、叶、花和/或果实。
6.根据权利要求1所述的一种天然草本茶含片，其特征在于：所述海藻酸盐采用海藻酸钠、海藻酸钾中的一种或者两种的组合物。
7.根据权利要求1所述的一种天然草本茶含片，其特征在于：所述辅料由甘草甜素、罗勒粉末香精、乳糖和麦芽糊精按照1:3:20:10的质量比混合而成。
8.根据权利要求7所述的一种天然草本茶含片，其特征在于：所述辅料的制备方法为：将甘草甜素、罗勒粉末香精采用等量递增法与乳糖和麦芽糊精配研混合后，再继续混合12-15min，得到辅料。
9.根据权利要求1-8任一项所述的一种天然草本茶含片的制备方法，其特征在于：包括如下步骤：
步骤一、按照上述重量百分数分别称取原料；
步骤二、取绿茶清洗干净，摊凉，蒸汽杀青，揉捻后微波干燥，多次粉碎、风选后得到粒径小于10um超微绿茶粉；
步骤三、取草本组合物，清洗干净、烘干后经水提醇沉获得提取浸液，将过滤后的提取液输送到提取液浓缩罐中进行浓缩，静置蒸发水分得到浸膏，将浸膏粉碎、过筛备用；
步骤四、将超微绿茶粉、草本组合物、木糖醇、海藻酸盐、壳寡糖、和辅料一起混合研磨后加入复合益生菌，通过模切的方法形成含片。
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115152868A (zh) * | 2022-06-01 | 2022-10-11 | 杭州国茶健康产业有限公司 | 一种基于赤藓糖醇的天然草本含茶饮料及其制备方法 |
Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1698839A (zh) * | 2005-06-22 | 2005-11-23 | 徐永福 | 一种清洁口腔异味预防龋齿的木糖醇绿茶制剂及其制备方法 |
| CN102462836A (zh) * | 2010-11-18 | 2012-05-23 | 冯小可 | 一种胖大海冲剂 |
| CN104738641A (zh) * | 2015-04-25 | 2015-07-01 | 哈药集团中药二厂 | 一种洛神花抗疲劳含片的制备方法 |
| CN105410913A (zh) * | 2015-12-01 | 2016-03-23 | 辽宁三合酒业有限公司 | 一种壳寡糖口腔清洁含片的制备方法 |
| CN106177190A (zh) * | 2016-08-15 | 2016-12-07 | 新疆环拓生物科技有限公司 | 一种清咽含片及其制备方法 |
| CN106581477A (zh) * | 2016-12-01 | 2017-04-26 | 李妍 | 一种吸烟者口气清新剂 |
| CN109832608A (zh) * | 2017-11-28 | 2019-06-04 | 内蒙古伊利实业集团股份有限公司 | 缓解咽喉不适的益生菌草本食品组合物及其含片制备方法 |
| CN110063374A (zh) * | 2019-05-28 | 2019-07-30 | 北京科拓恒通生物技术股份有限公司 | 一种用于改善口气的复合益生菌组合物、含片及其制备方法 |
| CN111568919A (zh) * | 2020-05-19 | 2020-08-25 | 上海中砥生物科技有限公司 | 一种含壳寡糖的抗幽门螺旋杆菌制剂 |
| CN113082149A (zh) * | 2021-04-28 | 2021-07-09 | 宋颖鹰 | 植物草本益生菌口腔含片及其制备方法 |
-
2022
- 2022-06-20 CN CN202210697684.XA patent/CN115212163A/zh active Pending
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1698839A (zh) * | 2005-06-22 | 2005-11-23 | 徐永福 | 一种清洁口腔异味预防龋齿的木糖醇绿茶制剂及其制备方法 |
| CN102462836A (zh) * | 2010-11-18 | 2012-05-23 | 冯小可 | 一种胖大海冲剂 |
| CN104738641A (zh) * | 2015-04-25 | 2015-07-01 | 哈药集团中药二厂 | 一种洛神花抗疲劳含片的制备方法 |
| CN105410913A (zh) * | 2015-12-01 | 2016-03-23 | 辽宁三合酒业有限公司 | 一种壳寡糖口腔清洁含片的制备方法 |
| CN106177190A (zh) * | 2016-08-15 | 2016-12-07 | 新疆环拓生物科技有限公司 | 一种清咽含片及其制备方法 |
| CN106581477A (zh) * | 2016-12-01 | 2017-04-26 | 李妍 | 一种吸烟者口气清新剂 |
| CN109832608A (zh) * | 2017-11-28 | 2019-06-04 | 内蒙古伊利实业集团股份有限公司 | 缓解咽喉不适的益生菌草本食品组合物及其含片制备方法 |
| CN110063374A (zh) * | 2019-05-28 | 2019-07-30 | 北京科拓恒通生物技术股份有限公司 | 一种用于改善口气的复合益生菌组合物、含片及其制备方法 |
| CN111568919A (zh) * | 2020-05-19 | 2020-08-25 | 上海中砥生物科技有限公司 | 一种含壳寡糖的抗幽门螺旋杆菌制剂 |
| CN113082149A (zh) * | 2021-04-28 | 2021-07-09 | 宋颖鹰 | 植物草本益生菌口腔含片及其制备方法 |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115152868A (zh) * | 2022-06-01 | 2022-10-11 | 杭州国茶健康产业有限公司 | 一种基于赤藓糖醇的天然草本含茶饮料及其制备方法 |
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Application publication date: 20221021 |