CN115066433A - 一种扩增增强子及其应用 - Google Patents

一种扩增增强子及其应用 Download PDF

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CN115066433A
CN115066433A CN202280001808.4A CN202280001808A CN115066433A CN 115066433 A CN115066433 A CN 115066433A CN 202280001808 A CN202280001808 A CN 202280001808A CN 115066433 A CN115066433 A CN 115066433A
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cell
amino acids
cells
mhc
transmembrane domain
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黄倬
林彦妮
赵珣
郑小翠
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Cure Genetics Co ltd
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Cure Genetics Co ltd
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Abstract

本发明涉及一种扩增增强子,该增强子包含一种能引发细胞STAT5和/或STAT3信号传导途径的胞内结构域、跨膜结构域和细胞外结构域的蛋白分子;本发明还涉及表达该扩增增强子的淋巴细胞及其作为免疫治疗药物的用途。

Description

PCT国内申请,说明书已公开。

Claims (26)

  1. PCT国内申请,权利要求书已公开。
CN202280001808.4A 2021-02-10 2022-02-10 一种扩增增强子及其应用 Pending CN115066433A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2021101848925 2021-02-10
CN202110184892 2021-02-10
PCT/CN2022/075873 WO2022171179A1 (zh) 2021-02-10 2022-02-10 一种扩增增强子及其应用

Publications (1)

Publication Number Publication Date
CN115066433A true CN115066433A (zh) 2022-09-16

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ID=82837479

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CN202280001808.4A Pending CN115066433A (zh) 2021-02-10 2022-02-10 一种扩增增强子及其应用

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US (1) US20240117007A1 (zh)
EP (1) EP4293041A1 (zh)
CN (1) CN115066433A (zh)
WO (1) WO2022171179A1 (zh)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6681837B2 (ja) 2014-03-11 2020-04-15 セレクティスCellectis 同種移植に適合するt細胞を作製するための方法
AU2017317022B2 (en) 2016-08-26 2021-12-09 Baylor College Of Medicine Constitutively active cytokine receptors for cell therapy
CN109694854B (zh) * 2017-10-20 2023-11-21 亘喜生物科技(上海)有限公司 通用型嵌合抗原受体t细胞制备技术
AU2019377461A1 (en) * 2018-11-06 2021-05-27 Washington University Chimeric antigen receptor memory-like (CARML) NK cells and methods of making and using same
CN113660942A (zh) * 2019-02-08 2021-11-16 西雅图儿童医院(Dba西雅图儿童研究所) 嵌合细胞因子受体

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WO2022171179A1 (zh) 2022-08-18
WO2022171179A8 (zh) 2023-11-02
EP4293041A1 (en) 2023-12-20
WO2022171179A9 (zh) 2022-09-15
US20240117007A1 (en) 2024-04-11

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