CN115040183B - Urinary surgery is with bladder urethra anastomotic device - Google Patents
Urinary surgery is with bladder urethra anastomotic device Download PDFInfo
- Publication number
- CN115040183B CN115040183B CN202210646177.3A CN202210646177A CN115040183B CN 115040183 B CN115040183 B CN 115040183B CN 202210646177 A CN202210646177 A CN 202210646177A CN 115040183 B CN115040183 B CN 115040183B
- Authority
- CN
- China
- Prior art keywords
- ring
- fixed
- urethra
- bladder
- fixing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 210000003708 urethra Anatomy 0.000 title claims abstract description 38
- 230000002485 urinary effect Effects 0.000 title claims abstract description 20
- 238000001356 surgical procedure Methods 0.000 title claims abstract description 11
- 230000003872 anastomosis Effects 0.000 claims abstract description 42
- 239000003814 drug Substances 0.000 claims abstract description 33
- 239000004005 microsphere Substances 0.000 claims abstract description 27
- 229940079593 drug Drugs 0.000 claims abstract description 25
- 210000003932 urinary bladder Anatomy 0.000 claims description 31
- 239000000843 powder Substances 0.000 claims description 15
- 239000000463 material Substances 0.000 claims description 13
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 12
- 210000001519 tissue Anatomy 0.000 claims description 10
- JVTAAEKCZFNVCJ-REOHCLBHSA-N L-lactic acid Chemical compound C[C@H](O)C(O)=O JVTAAEKCZFNVCJ-REOHCLBHSA-N 0.000 claims description 9
- 229920001432 poly(L-lactide) Polymers 0.000 claims description 9
- 238000002360 preparation method Methods 0.000 claims description 8
- 238000004108 freeze drying Methods 0.000 claims description 6
- 238000007710 freezing Methods 0.000 claims description 6
- 230000008014 freezing Effects 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims description 6
- 229910052757 nitrogen Inorganic materials 0.000 claims description 6
- 230000015556 catabolic process Effects 0.000 claims description 5
- 238000006731 degradation reaction Methods 0.000 claims description 5
- 238000004519 manufacturing process Methods 0.000 claims description 4
- 210000005068 bladder tissue Anatomy 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- 239000007787 solid Substances 0.000 claims description 2
- 238000003756 stirring Methods 0.000 claims description 2
- 229920001296 polysiloxane Polymers 0.000 claims 2
- 208000035965 Postoperative Complications Diseases 0.000 abstract description 3
- 238000000034 method Methods 0.000 description 8
- 239000000499 gel Substances 0.000 description 6
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 4
- 210000004712 air sac Anatomy 0.000 description 4
- 230000006378 damage Effects 0.000 description 4
- 239000000741 silica gel Substances 0.000 description 4
- 229910002027 silica gel Inorganic materials 0.000 description 4
- 206010061218 Inflammation Diseases 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000004054 inflammatory process Effects 0.000 description 3
- 238000010146 3D printing Methods 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000003467 diminishing effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 210000004197 pelvis Anatomy 0.000 description 1
- 238000007639 printing Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000002787 reinforcement Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 210000001635 urinary tract Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
- A61B17/115—Staplers for performing anastomosis in a single operation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00526—Methods of manufacturing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
- A61B2017/1132—End-to-end connections
Abstract
The invention aims to provide a bladder urethra anastomosis device for urinary surgery, which solves the problem that no anastomosis nail is used for high-efficiency and rapid anastomosis of bladder urethra and simultaneously reduces postoperative complications at present, and comprises the following steps: the device comprises a fixing ring, a drug microsphere, an anastomotic ring, a first auxiliary fixing component, a second auxiliary fixing component and an anastomotic ring conveying component.
Description
Technical Field
The invention belongs to the technical field of medical instruments for urinary surgery, and particularly relates to a bladder urethra anastomosis device for urinary surgery.
Background
For the operation requiring reconstruction of the lower urinary tract, the anastomosis of the bladder and the urethra is critical, the anastomosis difficulty is reflected in that the anastomosis opening is positioned at the bottom of the pelvis, the position is deep, the operation space is narrow, the suture technology difficulty is large, the operation time is long, and the anastomosis effect is difficult to ensure.
The anastomat can shorten the operation time and reduce the anastomotic difficulty; but the urethra has small lumen, short urethra broken end, pressure exists at the anastomotic stoma, and the anastomotic nail can induce the problems of calculus and the like.
Therefore, the invention of a non-anastomotic nail and an anastomat which can be anastomosed quickly and efficiently and can reduce the occurrence probability of inflammation and other complications after anastomosis is necessary, and the invention can also promote the clinical application of the bladder-urethra anastomat in the early days.
Disclosure of Invention
The invention aims to provide a bladder urethra anastomosis device for urinary surgery, which aims to solve the problem that no anastomat for high-efficiency and rapid anastomosis of bladder urethra and reduction of postoperative complications is lacking at present.
In order to solve the technical problems, the invention is realized by the following technical scheme:
A urinary bladder-urethra anastomosis device for use in urology, comprising: the device comprises a fixed ring, a drug microsphere, an anastomotic ring, a first auxiliary fixed component, a second auxiliary fixed component and an anastomotic ring conveying component, wherein a fixed needle and an air bag are arranged on the fixed ring, the fixed needle is vertically fixed on the outer surface of the fixed ring, the air bag is fixed on the inner surface of the fixed ring, the fixed needle contains the drug microsphere, the fixed needle and the drug microsphere are supported by a degradable material, the degradation time is 3-7 days, the air bag is inflated to prop up the fixed ring, and the fixed needle on the fixed ring is fixed in a tissue 1-2cm away from the urethra end or the bladder end; the two fixing rings are respectively positioned at the urethra end and the bladder end, the upper surface and the lower surface of the anastomotic ring are provided with an annular groove, the urethra end fixing ring is fixed in the groove on the lower surface of the anastomotic ring under the pulling of the first auxiliary fixing component, the bladder end fixing ring is fixed in the groove on the upper surface of the anastomotic ring under the pushing of the second auxiliary fixing component, and the anastomotic ring is conveyed to the position above the urethra end fixing ring through the anastomotic ring conveying component.
Further, the fixing ring further comprises: the air bag comprises a one-way valve and an air bag pipe, wherein the one-way valve is positioned on the air bag, one end of the air bag pipe penetrates through the one-way valve, and the other end of the air bag pipe is connected with an air pump.
Further, the fixed needles are arranged in groups of three and are sequentially and equidistantly arranged along the circle center clockwise.
Further, the first auxiliary fixing assembly includes: the utility model provides a draw bar, first bulge loop, bracing piece, support bar, side lever, first bulge loop position correspond urethra end solid fixed ring position, the draw bar with first bulge loop have the same centre of a circle, first bulge loop with the draw bar fix on the first auxiliary fixation subassembly upper surface, first auxiliary fixation subassembly lower surface connect the side lever, the side lever has at least three sections articulated together, the draw bar be hollow structure, the bracing piece be located inside the draw bar, the bracing piece with the draw bar have the same centre of a circle, the bracing piece connect at least three support bar, the support bar at least both ends articulated together.
Further, the second auxiliary fixing assembly includes: the push rod is positioned on the upper surface of the second auxiliary fixing component, the second convex ring is positioned on the lower surface of the second auxiliary fixing component, and the position of the second convex ring corresponds to the fixing ring at the bladder end.
Further, the anastomotic ring delivery assembly comprises: the elastic rod is connected with the fixing part, and the fixing part is connected with the clamping part.
Further, the preparation method of the drug microsphere comprises the following steps: after the animal bladder tissue is subjected to decellularization treatment, the decellularized gel is prepared, PLLA solution with 15% of the total gel amount is added into the decellularized gel, the solution is put into liquid nitrogen for quick freezing, freeze-drying treatment is performed, the freeze-dried bracket is ground into powder, the powder is added into medicine solution for 8 hours, and after the medicine solution is filtered, the temperature of an oven is adjusted to 45 ℃ for 48 hours.
Further, the preparation method of the fixed needle comprises the following steps: after PLLA with the weight fraction of 30 percent and PCL with the weight fraction of 70 percent are dissolved, 3-10g of medicine microsphere powder is added, and the mixture is stirred uniformly and printed and molded by a 3D printer.
Further, the fixing method of the fixing needle comprises the following steps: preparing a die, and manufacturing a triplet of dies according to the arrangement mode of the fixed needles; according to the weight fraction of PLLA and 60% PCL solution, adding 3-10g of drug microsphere powder, stirring uniformly, pouring into a mould, placing the mould in liquid nitrogen for quick freezing, then freeze-drying, and taking down the mould to finish the preparation.
Further, the fixing ring is made of elastic hard silica gel material, and the air bag is made of elastic soft silica gel material.
The invention has the following beneficial effects: the invention discloses a non-anastomotic device, which solves the problem of complications caused by the use of anastomotic nails; the degradable fixing needle and the drug microsphere can avoid the problem of long-term secondary injury to tissues, and simultaneously assist in diminishing inflammation and promoting the growth of the tissues, thereby further reducing the occurrence of complications such as inflammation; the anastomosis is carried out from the bladder end, so that the operation on the fragile urethra end is minimum, the damage to the tissue of the urethra end is reduced, and the anastomosis effect is ensured; the air bag can play a supporting role in the early action period, and after entering the groove at the back, part of air can be added according to actual conditions, so that the air bag has double functions of reinforcement and sealing.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings that are needed for the description of the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic view of the structure of a fixation ring of a urinary bladder-urethra anastomosis device for urinary surgery according to the present invention;
FIG. 2 is a schematic view of a balloon assembly of a urinary bladder-urethra anastomosis device according to the present invention;
FIG. 3 is a schematic view of a fixation needle arrangement of a urinary bladder-urethra anastomosis device according to the present invention;
FIG. 4 is a schematic view showing the structure of the inside of a fixing needle of the bladder-urethra anastomosis device for urinary surgery according to the present invention;
FIG. 5 is a schematic view showing the fixation of the urethral end of a urinary bladder-urethra anastomosis device for urinary surgery according to the invention;
FIG. 6 is a schematic view of the structure of a first auxiliary fixation assembly of a urinary bladder and urethra anastomosis device according to the invention;
FIG. 7 is a schematic view showing the securement of the bladder end of a urinary bladder-urethra anastomosis device for urinary surgery according to the invention;
fig. 8 is a schematic view of the construction of an anastomotic ring delivery device for a urinary bladder-urethra anastomosis device according to the present invention.
In the drawings, the list of components represented by the various numbers is as follows:
the fixation ring 1, the fixation needle 11, the balloon 12, the one-way valve 13, the balloon tube 14, the microsphere 2, the anastomotic ring 3, the groove 31, the first auxiliary fixation assembly 4, the pull rod 41, the first convex ring 42, the support rod 43, the support bar 44, the side rod 45, the second auxiliary fixation assembly 5, the push rod 51, the second convex ring 52, the anastomotic ring delivery assembly 6, the clamping part 61, the fixation part 62 and the elastic rod 63.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Example 1:
A urinary bladder-urethra anastomosis device for use in urology, comprising: the device comprises a fixed ring 1, a fixed needle 11, a balloon 12, a one-way valve 13, a balloon tube 14, a drug microsphere 2, an anastomotic ring 3, a groove 31, a first auxiliary fixing component 4, a pull rod 41, a first convex ring 42, a supporting rod 43, a supporting bar 44, a side rod 45, a second auxiliary fixing component 5, a push rod 51, a second convex ring 52, an anastomotic ring conveying component 6, a clamping part 61, a fixing part 62 and an elastic rod 63.
The fixing ring 1 includes: a fixing needle 11, a balloon 12, a one-way valve 13, and a balloon tube 14. As shown in figure 3, the fixing needles 11 are sequentially rotated by 120 degrees clockwise according to a triplet, are vertically fixed on the outer surface of the fixing ring 1 in a circular arrangement, an annular air bag 12 is fixed on the inner surface of the fixing ring 1, a one-way valve 13 is arranged on the air bag 12, the one-way valve 13 is connected with an air bag pipe 14, one end of the air bag pipe 14 is arranged in the air bag 12 in advance, the other end of the air bag pipe is connected with an air pump for inflating or deflating, and after the air bag pipe 14 is completely withdrawn, and the air in the air bag 12 is preserved due to the existence of the one-way valve 13.
The fixed ring 1 is made of elastic hard silica gel material, and the air sac 12 and the air sac tube 14 are made of elastic soft silica gel material, when in use, the fixed ring is pushed to a designated position, generally positioned at the position of a urethra port or a bladder port 1-2cm, the direction of the fixed ring is regulated after the position is reached, the air sac 12 is inflated slowly, so that the fixed ring 1 is driven to move around after the air sac is inflated, and the fixed needle 11 on the outer surface of the fixed ring 1 penetrates into tissues.
The pushing device of the fixed ring can be used for pushing the device by the existing pushing device by holding or pushing the device by self, in order to reduce matched conveying equipment and improve operation efficiency, the part of the air bag tube 14 positioned outside the air bag 12 can be replaced by hard materials for preparation, and when the device is used, the air bag tube 14 can be directly used for driving the fixed ring 1 to a designated position.
After the fixation ring 1 is supported by the balloon, the fixation needle 11 on the outer surface of the fixation ring 11 is fixed to the tissue with sufficient strength to firmly grasp the urethra or the tissue in the bladder on the outer surface of the fixation ring 1. The balloon tube 14 is disposed within the balloon 12 at a length of not less than 2cm, and is prevented from being easily pulled out during the procedure.
The fixed needle 11 is of a micro-needle structure design, the diameter of the largest part of the micro-needle is 0.5mm, the adopted rapid degradation material is supported, the rapid degradation material can be completely degraded within 3-7 days, the continuous damage to tissues is avoided, meanwhile, in order to reduce postoperative complications and accelerate the growth and healing of an anastomotic port, the drug microsphere 2 is added into the fixed needle 11, and the drug microsphere 2 is synchronously degraded along with the degradation of the fixed needle 11, so that the drug is released.
After the fixed ring 1 performs the opening fixation on the urethral port and the bladder port, the anastomosis of the two ends is performed, the anastomosis ring 3 is used, the anastomosis ring 3 comprises grooves 31 which are annular and are used for accommodating the fixed ring 1, and two grooves 31 are respectively arranged on the upper surface and the lower surface of the anastomosis ring 3.
Fixation ring 1 is secured in recess 31 of anastomosis ring 3 by first and second fixation assemblies 4, 5.
The first fixing assembly 4 includes: a pull rod 41, a first convex ring 42, a supporting rod 43, a supporting bar 44 and a side rod 45; the upper surface of the assembly is provided with a circle of first convex rings 42, the position of the first convex rings 42 is the same as that of the groove 31, a pull rod 41 is fixed on the upper surface of the assembly, the pull rod 41 is of a hollow structure, is concentric with the first convex rings 42 and is positioned in the first convex rings 42, and the pull rod is used for pulling the first fixing assembly 4 to fix the fixing ring 1 in the groove 31; the supporting rod 43 is positioned in the pull rod 41 and is concentric, the supporting rod 43, the side rods 45 and the supporting rod 44 are designed into an umbrella-shaped structure, the side rods 43 are provided with a plurality of sections, five sections are provided in the embodiment, the supporting rod 44 is provided with a plurality of sections, three sections are provided in the embodiment, the supporting rod 44 is provided with two ends in the embodiment, the sections between the supporting rod 44 and the side rods 45 are connected together through hinges, the supporting rod 44 is fixed on the supporting rod 43, the supporting rod 43 can move up and down, and when the supporting rod 43 moves down, the supporting rod 44 moves outwards to drive the side rods 45 to move outwards until the supporting rod is completely unfolded; the supporting rod 41 is pulled to place the fixing ring 1 in the groove 13 after the air bag 12 is partially deflated, and then the air bag tube 14 is slowly pulled out after the fixing ring 1 is completely fixed in the groove 13 and the supporting rod 43 is moved upwards, so that the supporting rod 44 and the side rod 45 are retracted, and the first fixing component 4 is removed.
The second auxiliary fixing assembly 5 includes: the push rod 51 and the second convex ring 52, the second convex ring 52 is positioned above the position of the fixed ring 1, the push rod 51 is fixed on the upper surface of the component, the push rod and the second convex ring 52 have the same circle center, the push rod 51 is pushed to drive the second auxiliary fixed component 5 to push the fixed ring 1 at the bladder end downwards into the groove 31 on the upper surface of the anastomotic ring 3, the fixing method is the same as the fixing method of the fixed ring 1 at the urethra end, namely, the balloon 12 is firstly partially deflated and then is fixed into the groove 31 and then inflated, so that the balloon is completely fixed in the groove 31, the balloon tube 14 is slowly pulled out, and the second auxiliary fixed device 5 is pulled out, so that the anastomosis of the bladder and the urethra is completed at the moment.
The diameters of the first convex ring 42 and the second convex ring 52 are slightly smaller than the diameter of the groove 31; the hinge is designed to facilitate the operation of the first fixing assembly 4 passing through the fixing ring 1 and being removed; in order to enhance the fixing effect of the groove 31 to the fixing ring 1, the surface of the groove 31 is provided in an uneven structure.
Anastomotic ring 3 is delivered by a self-contained anastomotic ring delivery assembly 6 comprising: the clamping part 61, the fixing part 62 and the elastic rod 63 are clamped in the groove 31, the clamping part 61 is connected with the fixing part 62, the fixing part 62 is connected with the elastic rod 63, the fixing part 62 is rotated by the elastic rod 63 to firmly fix the clamping part 61 on the inner wall of the groove 31, and after the clamping part moves to a preset position, the fixing part 62 is reversely rotated by the elastic rod 63 to enable the clamping part 61 to leave the groove 31. The placement of anastomotic ring 3 is: the position of the groove 31 is aligned on the fixing ring 1.
In order to fully utilize the large space of the bladder end and reduce the damage to the tissue of the urethra end, the embodiment adopts the transvesical anastomosis method, and the urethra end can be used for anastomosis.
Example 2:
Based on the embodiment 1, the drug microsphere 2 is a self-made degradable drug microsphere, and the preparation method of the drug microsphere is as follows:
After the animal bladder tissue is subjected to decellularization treatment, the decellularized gel is prepared, PLLA solution with 15% of the total gel amount is added into the decellularized gel, the solution is put into liquid nitrogen for quick freezing, freeze-drying treatment is performed, the freeze-dried bracket is ground into powder, the powder is added into medicine solution for 8 hours, and after the medicine solution is filtered, the temperature of an oven is adjusted to 45 ℃ for 48 hours.
Example 3:
Based on the embodiment 1, the fixing needle 11 containing the drug microsphere 2 is a self-made component, and the fixing needle is formed by a biocompatible adhesive or is formed together with the fixing ring 1, and the integrally formed manufacturing method includes, but is not limited to, a die method and a 3D printing method.
The manufacturing method of the fixed needle 11 comprises the following steps: after PLLA with the weight fraction of 30% and PCL with the weight fraction of 70% are dissolved, 3-10g of drug microsphere powder is added, the mixture is stirred uniformly, and a 3D printer is used for printing and molding, and 5g of drug microsphere powder is selected in the embodiment.
Example 4:
The difference from embodiment 3 is that the fixing needles 11 are manufactured by a mold method, firstly, a microneedle array mold is manufactured, the mold shape refers to the three groups of patterns of the fixing needles 11 in fig. 3, a group mold is manufactured, and one group of fixing needles 11 is manufactured at a time, so that the fixing of the subsequent fixing needles 11 is facilitated.
After PLLA with the weight fraction of 40% and PCL with the weight fraction of 60% are selected, 3-10g of drug microsphere powder is added, 5g of drug microsphere powder is selected in the embodiment, the drug microsphere powder is uniformly stirred and then poured into a mould, the mould is placed in liquid nitrogen for quick freezing, then freeze drying is carried out, and the mould is taken down, so that the preparation is completed.
In the description of the present specification, the descriptions of the terms "one embodiment," "example," "specific example," and the like, mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the present invention. In this specification, schematic representations of the above terms do not necessarily refer to the same embodiments or examples. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The preferred embodiments of the invention disclosed above are intended only to assist in the explanation of the invention. The preferred embodiments are not exhaustive or to limit the invention to the precise form disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the invention and the practical application, to thereby enable others skilled in the art to best understand and utilize the invention. The invention is limited only by the claims and the full scope and equivalents thereof.
Claims (10)
1. A urinary bladder-urethra anastomosis device for use in urology, comprising: the device comprises a fixed ring, a drug microsphere, an anastomotic ring, a first auxiliary fixed component, a second auxiliary fixed component and an anastomotic ring conveying component, wherein a fixed needle and an air bag are arranged on the fixed ring, the fixed needle is vertically fixed on the outer surface of the fixed ring, the air bag is fixed on the inner surface of the fixed ring, the fixed needle contains the drug microsphere, the fixed needle and the drug microsphere are supported by a degradable material, the degradation time is 3-7 days, the air bag is inflated to prop up the fixed ring, and the fixed needle on the fixed ring is fixed in a tissue 1-2cm away from the urethra end or the bladder end; the two fixing rings are respectively positioned at the urethra end and the bladder end, the upper surface and the lower surface of the anastomotic ring are provided with an annular groove, the urethra end fixing ring is fixed in the groove on the lower surface of the anastomotic ring under the pulling of the first auxiliary fixing component, the bladder end fixing ring is fixed in the groove on the upper surface of the anastomotic ring under the pushing of the second auxiliary fixing component, and the anastomotic ring is conveyed to the position above the urethra end fixing ring through the anastomotic ring conveying component.
2. The urological bladder and urethra anastomosis device of claim 1, wherein said securing ring further comprises: the air bag comprises a one-way valve and an air bag pipe, wherein the one-way valve is positioned on the air bag, one end of the air bag pipe penetrates through the one-way valve, and the other end of the air bag pipe is connected with an air pump.
3. The urinary bladder and urethra anastomosis device according to claim 1, wherein said fixation needles are arranged in triad, clockwise succession and equidistant along the center of the circle.
4. The urological bladder and urethra anastomosis device of claim 1, wherein said first auxiliary fixation assembly comprises: the utility model provides a draw bar, first bulge loop, bracing piece, support bar, side lever, first bulge loop position correspond urethra end solid fixed ring position, the draw bar with first bulge loop have the same centre of a circle, first bulge loop with the draw bar fix on the first auxiliary fixation subassembly upper surface, first auxiliary fixation subassembly lower surface connect the side lever, the side lever has at least three sections articulated together, the draw bar be hollow structure, the bracing piece be located inside the draw bar, the bracing piece with the draw bar have the same centre of a circle, the bracing piece connect at least three support bar, the support bar at least both ends articulated together.
5. The urological bladder and urethra anastomosis device of claim 1, wherein said second auxiliary fixation assembly comprises: the push rod is positioned on the upper surface of the second auxiliary fixing component, the second convex ring is positioned on the lower surface of the second auxiliary fixing component, and the position of the second convex ring corresponds to the fixing ring at the bladder end.
6. The urological bladder and urethra anastomosis device of claim 1, wherein said anastomosis ring delivery assembly includes: the elastic rod is connected with the fixing part, and the fixing part is connected with the clamping part.
7. The urinary bladder and urethra anastomosis device for urinary surgery according to claim 1, wherein the preparation method of the drug microsphere comprises the following steps: after the animal bladder tissue is subjected to decellularization treatment, the decellularized gel is prepared, PLLA solution with 15% of the total gel amount is added into the decellularized gel, the solution is put into liquid nitrogen for quick freezing, freeze-drying treatment is performed, the freeze-dried bracket is ground into powder, the powder is added into medicine solution for 8 hours, and after the medicine solution is filtered, the temperature of an oven is adjusted to 45 ℃ for 48 hours.
8. The urinary bladder and urethra anastomosis device according to claim 1, wherein said fixation needle is prepared by the steps of: after PLLA with the weight fraction of 30 percent and PCL with the weight fraction of 70 percent are dissolved, 3-10g of medicine microsphere powder is added, and the mixture is stirred uniformly and printed and molded by a 3D printer.
9. The urinary bladder and urethra anastomosis device according to claim 1, wherein said fixation needle is fixed by: preparing a die, and manufacturing a triplet of dies according to the arrangement mode of the fixed needles; according to the weight fraction of PLLA and 60% PCL solution, adding 3-10g of drug microsphere powder, stirring uniformly, pouring into a mould, placing the mould in liquid nitrogen for quick freezing, then freeze-drying, and taking down the mould to finish the preparation.
10. The urinary bladder and urethra anastomosis device of claim 1 wherein said retaining ring is of a resilient rigid silicone material and said balloon is of a resilient soft silicone material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210646177.3A CN115040183B (en) | 2022-06-09 | 2022-06-09 | Urinary surgery is with bladder urethra anastomotic device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210646177.3A CN115040183B (en) | 2022-06-09 | 2022-06-09 | Urinary surgery is with bladder urethra anastomotic device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN115040183A CN115040183A (en) | 2022-09-13 |
| CN115040183B true CN115040183B (en) | 2024-04-19 |
Family
ID=83161998
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210646177.3A Active CN115040183B (en) | 2022-06-09 | 2022-06-09 | Urinary surgery is with bladder urethra anastomotic device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115040183B (en) |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3163452U (en) * | 2010-08-04 | 2010-10-14 | 劉忠臣 | Sleeve-type anastomosis for fixation |
| CN202776433U (en) * | 2012-04-28 | 2013-03-13 | 黄健 | Transurethral urethra bladder anastomat |
| CN106580380A (en) * | 2016-12-23 | 2017-04-26 | 黄建能 | Degradable urethrovesical anastomosis apparatus |
| CN106938058A (en) * | 2017-03-27 | 2017-07-11 | 四川大学 | A kind of preparation method and application of de- acellular collagen gels microsphere support |
| CN107242891A (en) * | 2010-12-29 | 2017-10-13 | 爱德华兹生命科学卡迪尔克有限责任公司 | Improved surgical implant device and production and preparation method thereof |
| CN112754727A (en) * | 2021-04-07 | 2021-05-07 | 德宝恒生科技服务有限公司 | Urethra implant and urethra implant assembly |
| CN216060625U (en) * | 2021-01-08 | 2022-03-18 | 薛建新 | Annular structure for anastomat |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2688514A1 (en) * | 2011-03-21 | 2014-01-29 | Endo Pharmaceuticals Inc. | Urethral anastomosis device and method |
| EP2967556A1 (en) * | 2013-03-14 | 2016-01-20 | Endo Pharmaceuticals Inc. | Urethral anastomosis device |
-
2022
- 2022-06-09 CN CN202210646177.3A patent/CN115040183B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3163452U (en) * | 2010-08-04 | 2010-10-14 | 劉忠臣 | Sleeve-type anastomosis for fixation |
| CN107242891A (en) * | 2010-12-29 | 2017-10-13 | 爱德华兹生命科学卡迪尔克有限责任公司 | Improved surgical implant device and production and preparation method thereof |
| CN202776433U (en) * | 2012-04-28 | 2013-03-13 | 黄健 | Transurethral urethra bladder anastomat |
| CN106580380A (en) * | 2016-12-23 | 2017-04-26 | 黄建能 | Degradable urethrovesical anastomosis apparatus |
| CN106938058A (en) * | 2017-03-27 | 2017-07-11 | 四川大学 | A kind of preparation method and application of de- acellular collagen gels microsphere support |
| CN216060625U (en) * | 2021-01-08 | 2022-03-18 | 薛建新 | Annular structure for anastomat |
| CN112754727A (en) * | 2021-04-07 | 2021-05-07 | 德宝恒生科技服务有限公司 | Urethra implant and urethra implant assembly |
Also Published As
| Publication number | Publication date |
|---|---|
| CN115040183A (en) | 2022-09-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2006307601B2 (en) | Adjustable vaginal splint for pelvic floor support | |
| US7628156B2 (en) | Adjustable vaginal splint for pelvic floor support | |
| US20100168656A1 (en) | Apparatus and methods for treating urethral incontinence | |
| US8486095B2 (en) | Method and apparatus for radical prostatectomy anastomosis | |
| US20090062836A1 (en) | Balloon assisted occlusion device | |
| EP2265219B1 (en) | Implantable fluid devices | |
| US20070175487A1 (en) | Disposable Surgical Drape | |
| CN115040183B (en) | Urinary surgery is with bladder urethra anastomotic device | |
| CN114404797B (en) | Self-curling double-layer hydrogel microneedle patch and preparation method thereof | |
| CN216169334U (en) | Ureteral stent | |
| CN211067204U (en) | Degradable functional implantation capsule body for repairing soft tissue cavity defect | |
| CN110200667B (en) | Soft channel for neuroendoscopy operation and establishing method | |
| KR101170785B1 (en) | Amniotic membrane reinsertion device | |
| CN215608683U (en) | Expansion saccule capable of remaining in ureter | |
| CN219538640U (en) | Adjustable ostomy support | |
| CN215875109U (en) | Drug-withdrawable perfusion stent system | |
| CN219185514U (en) | Double-air-bag type drainage tube fixing device | |
| CN214485254U (en) | Outer trachea bracket | |
| CN211460455U (en) | Transplanting device | |
| CN2601686Y (en) | Bushing type air bag urinary catheter | |
| CN113476722A (en) | Ureteral stent | |
| CN112971947A (en) | Transplanting device | |
| AU2006307600B8 (en) | Adjustable vaginal splint for pelvic floor support | |
| CN115068022A (en) | Brain tissue expansion kit for craniocerebral operation | |
| CN108720800A (en) | A kind of Microendoscopic auxiliary visual field balloon-system |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| TA01 | Transfer of patent application right | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20230518 Address after: Unit 701, 7th floor, no.6, helix 3 Road, International Biological Island, Guangzhou, Guangdong 510000 Applicant after: GUANGZHOU SUN-SHING BIOTECH Co.,Ltd. Address before: No. 5, Qiufeng Road, Jun'an County, Shunde District, Foshan City, Guangdong Province, 528300 Applicant before: Zheng Bin |
|
| GR01 | Patent grant | ||
| GR01 | Patent grant |