CN1150016C - Medicine for treating fever caused by lupus erythematosus and other immunological disease - Google Patents

Abstract

The present invention relates to a medicine for treating fever caused by immune diseases such as systematic lupus erythematosus, etc., which is prepared from fineleaf schizonepeta herb, ledebouriella root, kudzuvine root, bupleurum root, rehmannia root, antelope horn, notopterygium root, largeleaf gentian root, honeysuckle flower, forsythia fruit, bezoar, calcite, clematis root, bear gall, red peony root, largetrifoliolious bugbane rhizome, platycodon root, licorice, etc. The medicine is used for treating multiple fever diseases caused by immune diseases such as systematic lupus erythematosus, etc.

Description

A kind of medicine that generates heat due to the lupus erythematosus immune disease for the treatment of

The present invention relates to the medicine that the caused heating of a kind of therapy system lupus erythematosus immune disease is not moved back, is to be the medicine that raw material forms according to certain prepared with the Chinese herbal medicine specifically.Belong to the field of Chinese medicines.

Systemic lupus erythematosus (sle) is that world's medical matters circle are referred to as one of four big difficult disease of wrecking the human life, and domestic and international interrelated data report, the sickness rate that every year should disease to be rapidly increasing progressively by a relatively large margin, to the mankind's threat not second to cancer and acquired immune deficiency syndrome (AIDS).In areas such as the Luo Qisite of the U.S., California, the sickness rate in its members of the same clan exceeds hundreds of times of general crowd up to 0.4-5%.Black people's sickness rate is three times in general crowd, and in the Black women of 15-45, per 245 people have a people to suffer from lupus erythematosus, is more common in the 15-25 young women in year especially.Before not using the 17-hydroxy-11-dehydrocorticosterone treatment, the primary disease mortality rate is very high, 80% patient dies from primary disease in 2 years, in recent years because the progress of diagnostic techniques and utilization 17-hydroxy-11-dehydrocorticosterone, the utilization of immunosuppressant, levamisole, antiviral drugs, antilymphocyte globulin thymosin and Chinese herbal medicine, the primary disease mortality rate progressively descends, and best survival rate has reached 80-85% in present 10 years.Though change is arranged, but, still have the part patient to die from organa parenchymatosums such as the heart, kidney, the brain infringement and the complication of primary disease because of various factors, hormone and the immunosuppressant of using both at home and abroad brought potential infection and transition to use this type of medicine to suppress the normal immunologic function of body to patient at present, destroyed organism balance, the patient is caused a disease because of lupus erythematosus, is exactly to cause death because of side effects of pharmaceutical drugs.Clinically, the lupus erythematosus disease often causes that heating do not move back, and uses conventional antipyretic to be difficult to prove effective, and brings very big misery to patient.

The object of the invention provides the medicine that generates heat due to a kind of effective treatment lupus erythematosus immune disease.

Medicine of the present invention is that the Chinese herbal medicine by the following weight proportioning forms according to certain prepared:

Herba Schizonepetae 10-12

Radix Saposhnikoviae 10-12

Radix Puerariae 10-15

Radix Bupleuri 10-15

Radix Rehmanniae 20-30

Cornu Saigae Tataricae 8-12

Rhizoma Et Radix Notopterygii 12-18

Radix Gentianae Macrophyllae 10-15

Flos Lonicerae 20-30

Fructus Forsythiae 10-15

Calculus Bovis 2-4

Mirabilitum crystallina 15-25

Radix Clematidis 8-15

Fel Ursi 1-1.8

Radix Paeoniae Rubra 10-15

Rhizoma Cimicifugae 10-15

Radix Platycodonis 6-10

Radix Glycyrrhizae 6-10

Medicine of the present invention preferably is prepared from by the Chinese medicine of following weight parts:

Herba Schizonepetae 11

Radix Saposhnikoviae 11

Radix Puerariae 13

Radix Bupleuri 13

The Radix Rehmanniae 25

Cornu Saigae Tataricae 10

Rhizoma Et Radix Notopterygii 15

Radix Gentianae Macrophyllae 12

Flos Lonicerae 25

Fructus Forsythiae 13

Calculus Bovis 3

Mirabilitum crystallina 20

Radix Clematidis 10

Fel Ursi 1.5

Radix Paeoniae Rubra 12

Rhizoma Cimicifugae 12

Radix Platycodonis 7

Radix Glycyrrhizae 7

In the middle of the above-mentioned raw materials medicine of the present invention, Calculus Bovis preferably uses natural Calculus Bovis, also can use the artificial Calculus Bovis to replace.Cornu Saigae Tataricae can use Cornu Bubali to replace.

Medicine of the present invention can be prepared into pharmaceutical dosage form commonly used clinically according to common process, preferred electuary.

Medicine of the present invention is according to the Traditional Chinese medical theory prescription; Herba Schizonepetae in the side; Radix Saposhnikoviae; the hot temperature of Rhizoma Et Radix Notopterygii is delivered diffusing wind; removing dampness to relieve pain; Radix Gentianae Macrophyllae; Radix Puerariae; hot cold evacuation of Radix Bupleuri; expelling pathogenic factors from muscles for reducing heat; wind-damp dispelling; Flos Lonicerae; Fructus Forsythiae; the Rhizoma Cimicifugae heat-clearing and toxic substances removing; wind-dispelling heat-dissipating; the Radix Paeoniae Rubra clearing away heat and cooling blood; eliminating stasis to stop pain; Cornu Saigae Tataricae; Fel Ursi; the artificial Calculus Bovis; the Mirabilitum crystallina heat-clearing and toxic substances removing; suppressing the hyperactive liver to relieve the wind syndrome, Radix Platycodonis lung qi dispersing sore-throat relieving can be all medicine ships; the medicine carrying come-up; can draw hardship and let out and descend, the Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, all medicines share; outer dispersing wind and cold; all wind-cold damp pathogens are separated interior clear all heat from the flesh table; poison; the stasis of blood goes out from urine, and all heat is all removed.Medicine with the preparation of above-mentioned prescription can make cutaneous vasodilation, promotes heat radiation, and respiratory movement is strengthened, and moisturizes to discharge and body temperature is descended.The person is all many to contain the total volatile oil in the medicine of the present invention, the eugenol in the total volatile oil, caproic acid, γ-undecanoic acid, lactone and be its antipyretic effective ingredient to a methoxybenzene diketone.Compositions expels the heat-evil by expelling pathogenic factors from the exterior and reaches the antipyretic purpose, can be used for the caused many heating diseases of immune disease such as systemic lupus erythematosus (sle).The expelling pathogenic factors from the exterior medicine of the hot temperature of utilization, Xin Liang and the product of heat-clearing and toxic substances removing nourishing YIN and clearing heat share to accumulate in the pyretic toxicity, the heresy of diseases caused by exogenous pathogenic factor six climate exopathogens and the heating disease of causing also has therapeutical effect preferably.

Embodiment:

Choose raw material according to following composition

Herba Schizonepetae 11

Radix Saposhnikoviae 11

Radix Puerariae 13

Radix Bupleuri 13

The Radix Rehmanniae 25

Cornu Saigae Tataricae 10

Rhizoma Et Radix Notopterygii 15

Radix Gentianae Macrophyllae 12

Flos Lonicerae 25

Fructus Forsythiae 13

The artificial Calculus Bovis 3

Mirabilitum crystallina 20

Radix Clematidis 10

Fel Ursi 1.5

Radix Paeoniae Rubra 12

Rhizoma Cimicifugae 12

Radix Platycodonis 7

Radix Glycyrrhizae 7

With the Cornu Saigae Tataricae in the middle of the said medicine, artificial Calculus Bovis's pulverize separately is powder; standby, surplus medicinal 4 times of water gagings decoct three times according to common process, filter; get filtrate concentrating; add 2 times of amount 95% ethanol precipitations, left standstill 24 hours, get supernatant concentration to extractum; then with above-mentioned each medicine mixing; drying is pulverized, and makes electuary.

Claims (3)

1, a kind of medicine that generates heat due to the lupus erythematosus immune disease for the treatment of is characterized in that this medicine is that Chinese medicine by following weight parts is prepared from:

Herba Schizonepetae 10-12

Radix Saposhnikoviae 10-12

Radix Puerariae 10-15

Radix Bupleuri 10-15

Radix Rehmanniae 20-30

Cornu Saigae Tataricae 8-12

Rhizoma Et Radix Notopterygii 12-18

Radix Gentianae Macrophyllae 10-15

Flos Lonicerae 20-30

Fructus Forsythiae 10-15

Calculus Bovis 2-4

Mirabilitum crystallina 15-25

Radix Clematidis 8-15

Fel Ursi 1-1.8

Radix Paeoniae Rubra 10-15

Rhizoma Cimicifugae 10-15

Radix Platycodonis 6-10

Radix Glycyrrhizae 6-10.

2, medicine according to claim 1 is characterized in that this medicine is that Chinese medicine by following weight parts is prepared from:

Herba Schizonepetae 11

Radix Saposhnikoviae 11

Radix Puerariae 13

Radix Bupleuri 13

The Radix Rehmanniae 25

Cornu Saigae Tataricae 10

Rhizoma Et Radix Notopterygii 15

Radix Gentianae Macrophyllae 12

Flos Lonicerae 25

Fructus Forsythiae 13

Calculus Bovis 3

Mirabilitum crystallina 20

Radix Clematidis 10

Fel Ursi 1.5

Radix Paeoniae Rubra 12

Rhizoma Cimicifugae 12

Radix Platycodonis 7

Radix Glycyrrhizae 7

3, medicine according to claim 1, the dosage form that it is characterized in that this medicine is an electuary.