CN114989961B - Detection device for detecting vaginal secretion - Google Patents

Detection device for detecting vaginal secretion Download PDF

Info

Publication number
CN114989961B
CN114989961B CN202210941607.4A CN202210941607A CN114989961B CN 114989961 B CN114989961 B CN 114989961B CN 202210941607 A CN202210941607 A CN 202210941607A CN 114989961 B CN114989961 B CN 114989961B
Authority
CN
China
Prior art keywords
detection
assembly
magnetic
waste liquid
platform
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202210941607.4A
Other languages
Chinese (zh)
Other versions
CN114989961A (en
Inventor
黎晖
刘冰凌
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ningbo Jiurui Biological Engineering Co ltd
Original Assignee
Ningbo Jiurui Biological Engineering Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ningbo Jiurui Biological Engineering Co ltd filed Critical Ningbo Jiurui Biological Engineering Co ltd
Priority to CN202210941607.4A priority Critical patent/CN114989961B/en
Publication of CN114989961A publication Critical patent/CN114989961A/en
Application granted granted Critical
Publication of CN114989961B publication Critical patent/CN114989961B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/44Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/90Protozoa ; Processes using protozoa
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/44Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from protozoa
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/924Hydrolases (3) acting on glycosyl compounds (3.2)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/36Gynecology or obstetrics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/70Mechanisms involved in disease identification
    • G01N2800/7095Inflammation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The present invention provides a detection device for detecting vaginal secretions, the detection device comprising: the detection seat is provided with a first installation space, and the top end of the detection seat is provided with a movable slide rail; a detection assembly, comprising: a support assembly provided with an output shaft rotating about a first axis; a detection platform; the detection installation position is provided with at least one first detection installation groove and at least one second detection installation groove which are sequentially arranged along a first direction; the liquid inlet arc-shaped channel is arranged at a first end of the detection installation position, and the first end is arranged along a first direction; the waste liquid channel is arranged at the second end of the detection mounting position, and the second end is opposite to the first end; the color identification component is connected to the movable sliding rail in a sliding mode and used for identifying the color of the detected card paper and the color of the vaginal secretion solution in a color reaction mode and generating a corresponding color signal. The invention solves the problem of low detection efficiency.

Description

Detection device for detecting vaginal secretion
Technical Field
The invention relates to the technical field of detection, in particular to a detection device for detecting vaginal secretion.
Background
Vaginitis is inflammation of vaginal mucosa and connective tissue under the mucosa, and is a common disease in gynecological outpatient service. Common vaginitis includes bacterial vaginitis (invasion of anaerobic bacteria such as gardnerella vaginalis and bacteroides), mycotic vaginitis (invasion of candida), trichomonas vaginitis (invasion of trichomonas), and the like.
In order to accurately detect the inflammation, a method for detecting vaginal biochemical markers is gradually used to diagnose vaginitis at home and abroad, and specifically, for example, each enzyme with chromogenic reaction capability is made into a detection card paper, and a sample solution mixed with vaginal secretion is dropped onto the detection card paper to observe color change displayed by the chromogenic reaction so as to judge the bacteria condition in the vaginal secretion.
However, the related art has at least one of the following technical problems: since the bacteria causing vaginitis are various, in order to obtain a more accurate and reliable detection structure, the sample solution is often dropped onto the corresponding detection card by manual or mechanical setting procedures to perform color reaction, and as described above, since the bacteria are various, the corresponding detection card also needs to be made, and thus, a great amount of time is spent in the dropping step set by manual or mechanical procedures, and the overall detection efficiency is low.
Disclosure of Invention
The invention solves the problem of low detection efficiency.
To solve the above problems, the present invention provides a detection device for detecting vaginal discharge, comprising: the detection seat is provided with a first installation space; the detection assembly is arranged in the first installation space and comprises: a support assembly provided with an output shaft rotating about a first axis; the detection platform is matched with the output shaft to be rotationally connected to the support assembly; one side of the detection platform, which is far away from the support component, is a first detection surface; the detection mounting position is arranged on the first detection surface; the detection installation position is provided with a plurality of detection installation grooves which are sequentially arranged along a first direction, an isolation bulge structure is arranged between any two adjacent detection installation grooves, at least one first detection installation groove and at least one second detection installation groove exist in the detection installation grooves, a first distance is formed between the first detection installation groove and the first axis, and a second distance which is larger than the first distance is formed between the second detection installation groove and the first axis; the detection installation position is used for placing various detection pieces, and the detection pieces comprise detection paper jams; the liquid inlet arc-shaped channel extends along the first direction, is arranged at the first end of the detection mounting position and is communicated with the detection mounting grooves; the waste liquid channel extends along the first direction, is arranged at a second end of the detection mounting position, is opposite to the first end, and is communicated with the detection mounting grooves; when the output shaft drives the detection platform to rotate along a first rotating direction, vaginal secretion solution in the liquid inlet arc-shaped channel sequentially passes through the liquid inlet arc-shaped channel, the detection assembly and the waste liquid channel.
Compared with the prior art, the technical effect achieved by adopting the technical scheme is as follows: the vaginal secretion solution can be independently subjected to color reaction with each detection card paper only by pouring the vaginal secretion solution into the liquid inlet arc-shaped channel and by means of the rotary detection platform, compared with the related art, the operation that multiple times of liquid dropping is required by manual means is avoided, the detection efficiency is greatly improved, and the detection difficulty is reduced; in addition, the detection device in the technical scheme has a simple and reliable structure. When detecting the operation next time in the face, can pour into liquid arc passageway with bactericidal solution in advance, combine foretell rotatory process, can carry out germicidal treatment to each detection mounting groove, and need not the manual work and carry out cleaning treatment to each detection mounting groove. Further, because two adjacent detection mounting grooves are provided with the protruding structure of isolation between them, avoided locating respectively wherein the detection card paper appearance the color development reaction that the colour is close to lead to the experimenter to accurately distinguish to cause the condition of missing the judgement or erroneous judgement to appear, further improvement detect accuracy and efficiency.
In an example of the present invention, the detection platform is a disc structure, each of the detection installation grooves is an arc groove, and the detection installation groove is curved along a circumferential direction of the detection platform; wherein, as the detection platform rotates around the first rotation direction, the distance between the detection installation groove and the first axis gradually increases.
Compared with the prior art, the technical scheme has the following technical effects: specifically, the structural feature who combines to detect the mounting groove can make the vaginal secretion solution that flows in cover to locating wherein on the detection card paper fast, avoids the diffusion velocity of vaginal secretion solution in this detection mounting groove too slow and influence the testing result.
In one example of the present invention, the support assembly includes: a drive assembly for driving the output shaft to rotate about the first axis in a first rotational direction; a first drainage bulge is arranged in the liquid inlet arc-shaped channel, a drainage inclined plane which inclines towards the detection installation position is arranged on the first drainage bulge, and the drainage inclined plane is used for draining the vaginal secretion solution in the liquid inlet arc-shaped channel into the detection installation position; a first blocking bulge is arranged in the waste liquid channel, a blocking inclined plane deviating from the detection installation position is arranged on the first blocking bulge, and the blocking inclined plane is used for blocking waste liquid in the waste liquid channel from entering the detection assembly; wherein the waste liquid is the solution after the vaginal secretion solution reacts with the detection assembly; the drainage inclined plane and the blocking inclined plane incline towards the same direction.
Compared with the prior art, the technical scheme has the following technical effects: in a specific example, in combination with the actual detection process, in the process of starting the driving assembly, it can be understood that, in the starting stage, the detection platform is rotated in an accelerated manner, so that the vaginal secretion solution placed in the liquid inlet arc-shaped channel in advance tends to move towards the direction away from the rotating direction, and in order to enable as much solution as possible to enter the corresponding detection installation groove in a short time, the waste liquid channel, the plurality of detection installation grooves and the liquid inlet arc-shaped channel are sequentially arranged along the first rotating direction, so that under the action of the accelerated speed, the solution can rapidly enter the corresponding detection installation groove, and the centrifugal motion of the solution which is close to the liquid inlet arc-shaped channel and far away from the inner wall of the detection installation groove and far away from the first axial direction is avoided in the starting stage, thereby reducing the total amount of the vaginal secretion solution which enters the plurality of detection installation grooves and participates in the color development reaction, and increasing the waste of the sample solution. Further, combine above-mentioned concrete example content, owing to have the drainage inclined plane, can be with in as much as possible solution drainage to corresponding detection mounting groove, and owing to the drainage inclined plane with block that the inclined plane all is the same direction slope of orientation, can understand, after the waste liquid enters into the waste liquid passageway, can hinder the waste liquid to flow back to this detection mounting groove through blocking the inclined plane this moment, especially combine to be in the end stage that slows down to stop at testing platform, further effectively prevented the backward flow condition of waste liquid and appeared.
In one example of the invention, the liquid inlet arc-shaped channel extends along the direction away from the first axis, and the channel width of the liquid inlet arc-shaped channel is gradually reduced; and/or the waste liquid channel extends along the direction away from the first axis, and the channel width of the waste liquid channel is gradually increased; and/or, the liquid inlet arc-shaped channel and the waste liquid channel bend towards the same direction, the liquid inlet arc-shaped channel is in the channel depth formed on the first detection surface is H1, the waste liquid channel is in the channel depth formed on the first detection surface is H2, and H1 is less than H2.
Compared with the prior art, the technical scheme has the following technical effects: in combination with the actual detection process, it is conceivable that the evaporation rate of the vaginal secretion solution exposed to the air is positively correlated with the surface area of the solution, that is, the evaporation efficiency is higher when the surface area of the solution is larger, and thus, the evaporation amount of the vaginal secretion solution can be reduced to a certain extent by gradually reducing the width of the channel; in addition, especially, the detection mounting grooves far away from the first axis can be ensured to have color reaction with the vaginal secretion solution, so that the vaginal secretion solution is prevented from being evaporated or remaining in the liquid inlet arc-shaped channel to cause the waste of the vaginal secretion solution.
In an example of the present invention, the detection platform is provided with a connecting shaft and a plurality of fan-shaped elastic plates fixedly arranged around the connecting shaft, and each fan-shaped elastic plate is provided with one detection installation position, one liquid inlet arc-shaped channel and one waste liquid channel, wherein the detection installation position is clamped by the one detection arc-shaped channel and the one waste liquid channel; the fan-shaped elastic plate can deform along the axial direction of the connecting shaft, and the axial line of the connecting shaft is superposed with the first axial line; the support assembly includes: the disc supporting seat is coaxially arranged with the detection platform, a planetary toothed belt, a driving gear and a plurality of planetary gears are arranged in the disc supporting seat, the plurality of planetary gears are clamped between the planetary toothed belt and the driving gear, and the number of teeth of the driving gear is more than that of the planetary gears; the magnetic assembly is arranged on at least one of the planetary gears and used for magnetically attracting the magnetic metal piece arranged on one side of the detection platform close to the support assembly so as to enable the fan-shaped elastic plate to move towards the direction close to the magnetic assembly; when the magnetic assembly is matched with the fan-shaped elastic plate in a magnetic attraction mode, the distance formed between the first detection mounting groove and the disc supporting seat is smaller than the distance formed between the second detection mounting groove and the disc supporting seat.
Compared with the prior art, the technical scheme has the following technical effects: in a specific example, each fan-shaped elastic plate can detect a single vaginal secretion solution, and the fan-shaped elastic plates can correspondingly detect multiple vaginal secretions, so that the detection efficiency is greatly improved; in addition, the magnetic component can be used for magnetically attracting the detection platform, so that the end part of the fan-shaped elastic plate which is magnetically attracted and matched with the magnetic component, close to the first axis, is positioned at a higher position, and the end part far away from the first axis is positioned at a lower position, namely, the higher position corresponds to the distance formed between the first detection mounting groove and the disc supporting seat, and the lower position corresponds to the distance formed between the second detection mounting groove and the disc supporting seat. Then, at testing platform carry out the in-process of rotation, except under the effect of centrifugal force, can make vaginal secretion solution flow fast on the first detection face of fan-shaped elastic plate, can also inhale the cooperation with the aid of magnetism between magnetic component and the fan-shaped elastic plate, further improved the flow rate of vaginal secretion solution, further reduced the dwell time of this solution in income liquid arc passageway, waste liquid passageway and detection mounting groove.
In an example of the invention, a limiting plate is arranged at one end of the disc supporting seat close to the detection platform, and the limiting plate extends towards the direction close to the circle center of the disc supporting seat so as to at least partially cover the planetary gear at the corresponding position; a first height is formed between the planetary gear and the limiting plate; a first interval is formed between any two adjacent fan-shaped elastic plates, and the first interval can be used for the magnetic assembly to pass through; in the process that the supporting assembly drives the detection platform to rotate, the detection device is switched between a first detection state and a second detection state.
Compared with the prior art, the technical scheme has the following technical effects: on one hand, the limiting plate is arranged at the top end of the disc supporting seat to prevent the planetary gear connected with the magnetic assembly from being separated from the disc supporting seat when the magnetic assembly and the detection platform generate magnetic action, namely, the planetary gear is separated from the driving gear, so that the detection platform cannot be switched between a first detection state and a second detection state in the rotation process, for example, at least one fan-shaped elastic plate is always in a deformation inclined state, and further the flow rate of vaginal secretion solution on the fan-shaped elastic plate is too high; on the other hand, the first interval is arranged between any two adjacent fan-shaped elastic plates, so that each fan-shaped elastic plate can be kept relatively independent as much as possible, and mutual interference is avoided. The detection platform can be switched between the first detection state and the second detection state without human intervention by combining the structural characteristics that the first interval can be used for penetrating through the magnetic assembly, so that the diffusion rate of the vaginal secretion solution can be effectively adjusted.
In one example of the invention, the magnetic assembly is provided with magnetic protruding blocks protruding towards the detection platform, and the magnetic protruding blocks are matched with the planetary gears one by one; and an adjusting distance with variable size is formed between the magnetic convex block and the detection platform; wherein the magnetic radius of the magnetic convex block is smaller than the maximum value of the adjusting distance; when the planetary gear is in the first detection state, the magnetic convex blocks are matched with the corresponding fan-shaped elastic plates in a magnetic attraction manner, the top end surfaces of the planetary gears are abutted with the bottom end surfaces of the limiting plates, and the fan-shaped elastic plates deform; when the second detection state is detected, the magnetic convex blocks are in magnetic fit with the corresponding fan-shaped elastic plates, the top end faces and the bottom end faces form the first height, and the fan-shaped elastic plates are horizontally arranged.
Compared with the prior art, the technical effect achieved by adopting the technical scheme is as follows: further improves the effect of effectively regulating the diffusion rate of the vaginal secretion solution so as to improve the detection efficiency.
In one example of the present invention, the disc support base includes: the supporting bottom plate is provided with at least one arc-shaped protruding piece at one side close to the detection platform, and the arc-shaped protruding piece is used for lifting the corresponding planetary gear to a second height in the direction close to the limiting plate; the circular ring track is provided with the planet toothed belt, the circular ring track surrounds the outer edge of the supporting bottom plate, a transmission space is formed by the circular ring track and the supporting bottom plate in a surrounding mode, and the transmission space is used for accommodating the driving gear and the plurality of planet gears; wherein, first height is D1, the radius of inhaling is D, the second height is D2, adjusting distance is D3, adjusting distance's maximum value is D3 max ,D2≤D1<D3 max ,D3 max -D2≤D<D3 max
Compared with the prior art, the technical scheme has the following technical effects: the detection platform can be flexibly switched between the first detection state and the second detection state in the rotation process without human interference, and the overall detection efficiency is improved.
In one embodiment of the present invention, the top end of the detection seat is provided with a movable slide rail; detection device is including locating the colour identification component of removal slide rail, the colour identification component includes: the transmission main body is connected with the movable slide rail in a sliding manner, and an electric control assembly is arranged in the transmission main body; the distance sensor is arranged at one end of the transmission main body, which is far away from the movable slide rail, and the distance sensor is arranged opposite to the detection mounting position; the color recognition sensor is arranged in the transmission main body in parallel with the distance sensor and is used for recognizing the color of a detection piece arranged at the detection mounting position and acquiring a color signal; when the transmission main body moves along the movable sliding rail, the distance sensor acquires a long signal and a short signal corresponding to the detection platform; the long signal corresponds to the positions of the plurality of detection mounting grooves; the short signal corresponds to the isolation bump structure; and the display component is connected to the detection seat and is used for converting the long signal, the short signal and the color signal into visual information.
Compared with the prior art, the technical effect achieved by adopting the technical scheme is as follows: through the color recognition component, the color recognition can replace human eyes to directly carry out color discrimination on the detected paper jam, so that the accuracy of detection result judgment is improved.
In another aspect, the present invention also provides a detection method applied to the detection device in any one of the above examples; the detection method comprises the following steps: s1, preparing a vaginal secretion solution, and placing the vaginal secretion solution in a corresponding reagent tube to keep stirring for a first preset time; s2, placing a plurality of detection pieces in each first detection mounting groove and each second detection mounting groove; s3, sucking a first component of the stirred vaginal secretion solution by using a suction nozzle assembly, and injecting the first component to a position, close to the output shaft, of the first detection mounting groove; s4, controlling a driving assembly in the supporting assembly to drive the detection platform to rotate around a second direction for a second preset time so that the vaginal secretion solution enters each corresponding detection installation position from the liquid inlet arc-shaped channel; s5, when the rotation time of the detection platform meets the second preset time, controlling the detection platform to stop at a first position through the driving assembly; s6, controlling a color recognition component to move on the movable slide rail so as to obtain the color signal of the same vaginal secretion solution participating in color development reaction; s7, converting the color signal into a visible signal through a signal converter electrically connected with the color identification component; s8, displaying the visual signal on a display screen through a display component of the detection device; s9, judging the bacterial condition in the vaginal secretion according to the display result on the display screen; when the detection platform is located at the first position, the projection of the color identification assembly in the vertical direction is located between the liquid inlet arc-shaped channel and the waste liquid channel and corresponds to the positions of the detection mounting grooves.
Compared with the prior art, the technical effect achieved by adopting the technical scheme is as follows: the technical effects corresponding to any one of the above technical solutions can be achieved, and are not described herein again.
After the technical scheme of the invention is adopted, the following technical effects can be achieved:
(1) The vaginal secretion solution can be independently subjected to color reaction with each detection card paper only by pouring the vaginal secretion solution into the liquid inlet arc-shaped channel and by means of the rotary detection platform, compared with the related art, the operation that multiple times of liquid dropping is required by manual means is avoided, the detection efficiency is greatly improved, and the detection difficulty is reduced; in addition, the detection device in the technical scheme has a simple and reliable structure. When next detection operation in the face, can pour into liquid arc passageway with bactericidal solution in advance, combine foretell rotatory process, can detect the mounting groove to each and carry out germicidal treatment, and need not the manual work and carry out cleaning treatment to each detection mounting groove. Furthermore, due to the fact that the isolation bulge structure is arranged between the two adjacent detection mounting grooves, the situation that a tester cannot accurately distinguish the detection card papers to cause the occurrence of the condition of missing judgment or erroneous judgment due to the fact that the detection card papers respectively arranged in the detection mounting grooves have color development reactions with similar colors is avoided to a certain extent, and the detection accuracy and efficiency are further improved;
(2) In a specific example, in combination with the actual detection process, in the process of starting the driving assembly, it can be understood that, in the starting stage, the detection platform is rotated in an accelerated manner, so that the vaginal secretion solution placed in the liquid inlet arc-shaped channel in advance tends to move towards the direction away from the rotating direction, and in order to enable as much solution as possible to enter the corresponding detection installation groove in a short time, the waste liquid channel, the plurality of detection installation grooves and the liquid inlet arc-shaped channel are sequentially arranged along the first rotating direction, so that under the action of the accelerated speed, the solution can rapidly enter the corresponding detection installation groove, and the centrifugal motion of the solution which is close to the liquid inlet arc-shaped channel and far away from the inner wall of the detection installation groove and far away from the first axial direction is avoided in the starting stage, thereby reducing the total amount of the vaginal secretion solution which enters the plurality of detection installation grooves and participates in the color development reaction, and increasing the waste of the sample solution. Furthermore, combine above-mentioned concrete example content, owing to have the drainage inclined plane, can be with in as much as possible solution drainage to corresponding detection mounting groove, and because drainage inclined plane with block the inclined plane and all be the same direction slope of orientation, can understand, after the waste liquid enters into the waste liquid passageway, can hinder the waste liquid to flow back to this detection mounting groove through blockking the inclined plane this moment, especially combine to be in the final phase that slows down to stop at testing platform, further effectively prevented the backward flow condition of waste liquid to appear.
Drawings
Fig. 1 is a schematic structural diagram of a detection apparatus for detecting vaginal discharge according to an embodiment of the present invention.
Fig. 2 is a schematic structural diagram of fig. 1 from another view angle.
Fig. 3 is a partial schematic view of fig. 2.
Fig. 4 is a schematic structural diagram of the detection assembly in fig. 1.
Fig. 5 is a cross-sectional view from another perspective of the detection assembly of fig. 4 without a waste collection member.
Fig. 6 is an exploded view of fig. 4.
FIG. 7 is a schematic structural diagram of the testing platform shown in FIG. 6.
Fig. 8 is an enlarged view of fig. 7 at a.
Fig. 9 is a schematic structural view of the support assembly in fig. 6.
Fig. 10 is a sectional view taken along the line B-B in fig. 9.
Fig. 11 is an enlarged view at C in fig. 10.
Fig. 12 is an enlarged view of fig. 11 at E.
Fig. 13 is a schematic view of the planetary gear and magnetic assembly of fig. 9.
Fig. 14 is a schematic flowchart of a detection method according to a second embodiment of the present invention.
Description of reference numerals:
100-a detection device; 101-a first rotational direction; 102-a nozzle; 103-an elastic connection; 104-a reagent tube; 10-a detection seat; 11-a first installation space; 12-moving the slide rail; 20-a detection component; 21-a detection platform; 211 — a first detection face; 212-a sector elastic plate; 213-first interval; 22-detecting the mounting groove; 23-a support assembly; 231-an output shaft; 232-a magnetic component; 2321-magnetic bump; 233-support the bottom plate; 234-circular orbit; 235-planetary toothed belts; 236-planetary gear; 2361-arc transition surface; 237-a drive gear; 238-arc protrusion; 239-a limit plate; 24-a waste liquid collection member; 25-isolating raised structures; 30-a color identification component; 41-liquid inlet arc-shaped channel; 411-drainage bevel; 42-a waste channel; 421-stop ramp.
Detailed Description
In order to make the aforementioned objects, features and advantages of the present invention comprehensible, embodiments accompanied with figures are described in detail below.
The first embodiment is as follows:
referring to fig. 1, a schematic structural diagram of a detection apparatus 100 for detecting vaginal discharge according to an embodiment of the present invention is shown. Referring to fig. 2 to 13, the detecting device 100 includes, for example, a detecting base 10, a detecting member 20, a liquid inlet arc channel 41 and a waste liquid channel 42.
Specifically, the detection seat 10 is provided with a first installation space 11; the detection assembly 20 is arranged in the first installation space 11, specifically, the detection assembly 20 includes, for example, a support assembly 23, a detection platform 21 and a detection installation position, the support assembly 23 is provided with an output shaft 231 rotating around a first axis; the detection platform 21 is connected in rotation to the support assembly 23 by cooperating with the output shaft 231; and one side of the detection platform 21 away from the support assembly 23 is a first detection surface 211; the detection installation position is arranged on the first detection surface 211; the detection installation position is provided with a plurality of detection installation grooves 22 which are sequentially arranged along a first direction, wherein an isolation bulge structure 25 is arranged between any two adjacent detection installation grooves 22, at least one first detection installation groove and at least one second detection installation groove exist in the plurality of detection installation grooves 22, a first distance is formed between the first detection installation groove and a first axis, and a second distance which is larger than the first distance is formed between the second detection installation groove and the first axis; wherein, detect the installation position and be used for placing multiple detection piece, detection piece is including detecting the card paper.
Further, the liquid inlet arc-shaped channel 41 is arranged at the first end of the detection installation position, and the liquid inlet arc-shaped channel 41 is communicated with the plurality of detection installation grooves 22; the waste liquid channel 42 is arranged at the second end of the detection mounting position, the second end is opposite to the first end, and the waste liquid channel 42 is communicated with the detection mounting grooves 22; when the output shaft 231 drives the detection platform 21 to rotate around the first rotation direction 101, the vaginal secretion solution in the liquid inlet arc-shaped channel 41 sequentially passes through the liquid inlet arc-shaped channel 41, the detection assembly 20 and the waste liquid channel 42.
In a specific example, the detection card papers include seven detection card papers, correspondingly, different reaction enzymes are respectively arranged on the seven detection card papers, for the convenience of understanding and distinguishing, the seven detection card papers are respectively a first detection card paper, a second detection card paper, a third detection card paper, a fourth detection card paper, a fifth detection card paper, a sixth detection card paper and a seventh detection card paper, according to the actual detection requirement, for example, leukocyte esterase can be arranged on the first detection card paper, when a color development reaction occurs to vaginal secretion solution, the first detection card paper is made to appear blue, which indicates positive, and then the target object with the vaginal secretion is determined to have vaginitis; for example, sialidase may be disposed on the second detection cardboard, and when the vaginal secretion solution and the sialidase undergo a color reaction, the second detection cardboard is made to display purple red, and if the second detection cardboard is positive, the type of vaginitis is determined to be bacterial vaginitis; for example, a coagulase may be disposed on the third detection card, when the vaginal secretion solution and the coagulase are subjected to color reaction, the third detection card is made to show purple red, and the third detection card is indicated as positive, and the vaginitis is determined to be caused by aerobic bacteria, such as staphylococcus aureus and enterococcus faecalis escherichia coli; for example, N-acetylglucosaminidase may be disposed on the fourth detection cardboard, the fifth detection cardboard may be PH paper, proline aminopeptidase may be disposed on the sixth detection cardboard, and β -glucuronidase may be disposed on the seventh detection cardboard. When the vaginal secretion solution and the N-acetylglucosaminidase perform a color reaction, the fourth detection card paper is made to show yellow and show positive, and when the sixth detection card paper shows yellow and the PH value shown by the PH test paper is more than or equal to 4.8, namely, blue, the type of the vaginitis is judged to be the trichomonas vaginitis; for example, when the fourth detection card paper shows yellow, the sixth detection card paper shows yellow, and the PH value shown by the PH test paper is less than or equal to 4.6, that is, the fifth detection card paper shows yellow, the type of the vaginitis is determined to be mycotic vaginitis; for example, when the seventh detection card paper and the vaginal secretion solution are subjected to a color reaction, the seventh detection card paper is made to display blue, and the color is positive, and then the vaginitis is judged to be caused by aerobic bacteria infection.
Specifically, on the basis of the above specific example, in combination with the present technical solution, the number of the detection mounting slots 22 is also seven, for example, the detection jam can be disposed in one-to-one correspondence with the detection mounting slots 22, and since the distance between the first detection mounting slot and the first axis is not equal to the distance between the second detection mounting slot and the first axis, in brief, the first detection surface 211 can be, for example, a circular surface, the first axis is perpendicular to the circular surface and passes through the center of the circular surface, and the first direction is the same as any radial direction of the circular surface, so that the distances formed between the plurality of detection mounting slots 22 in the first direction and the first axis are not equal to each other.
Further, the detection installation slot 22 is provided with, for example, a first opening and a second opening, the first opening is communicated with the liquid inlet arc-shaped channel 41, the second opening is communicated with the waste liquid channel 42, after the vaginal secretion solution is poured into one end of the liquid inlet arc-shaped channel 41 close to the first axis, the detection platform 21 is made to rotate around the first axis along the first rotation direction 101, so that, under the action of centrifugal force, the vaginal secretion solution is made to move away from the first axis direction in the liquid inlet arc-shaped channel 41, specifically, due to the characteristic that the detection installation slot 22 is communicated with the liquid inlet arc-shaped channel 41, so that a part of the vaginal secretion solution enters each detection installation slot 22 through the plurality of first openings, and further, the detection jam occurs color reaction with the corresponding detection card paper arranged in the detection installation slot 22, so as to obtain the detection result of the vaginal secretion solution, and then the vaginal secretion solution is collected in the waste liquid channel 42 from the respective detection installation slot 22 through the plurality of second openings.
Wherein, it should be noted that, because the both ends that detect mounting groove 22 set up for the opening, and then avoided vaginal secretion solution after detecting the card paper, gather in respective detection mounting groove 22, until overflowing in order to flow into liquid arc channel 41 from first opening is reverse, and then this part can get into remaining detection mounting groove 22 through color reaction's vaginal secretion solution, thereby cause the influence to whole testing result, reduce the accuracy that detects, lead to unable concrete state to vaginal secretion to make the analysis.
More specifically, while the rotation in the first rotation direction 101 is maintained, for example, the vaginal secretion solution flowing into the first detection mounting groove enters the waste liquid channel 42 along with the rotation of the detection platform 21, and since the waste liquid channel 42 also extends along the first direction, the waste liquid after color development reaction flows away from the corresponding second opening due to the centrifugal force generated during the rotation. And combine to keep apart protruding structure 25, avoid flowing into the direct flow of vaginal secretion solution in the first detection mounting groove in the second detects the mounting groove, lead to reducing detection accuracy.
Therefore, the detection device 100 provided by the technical scheme can realize that the vaginal secretion solution can relatively independently perform color reaction with each detection card paper by only pouring the vaginal secretion solution into the liquid inlet arc-shaped channel 41 and by means of the rotary detection platform 21, compared with the related art, the operation of dropping liquid for multiple times by using a manual means is avoided, the detection efficiency is greatly improved, and the detection difficulty is greatly reduced; in addition, the detection device 100 in the present technical solution has a simple and reliable structure. When the next detection operation is performed, the sterilization solution can be poured into the liquid inlet arc-shaped channel 41 in advance, and in combination with the above-described rotation process, the sterilization treatment can be performed on each detection mounting groove 22 without manually cleaning each detection mounting groove 22. Further, because the isolation convex structures 25 are arranged between the two adjacent detection mounting grooves 22, the situation that a tester is difficult to accurately distinguish when color development reaction with similar colors occurs in detection card paper arranged in the detection mounting grooves respectively is avoided to a certain extent, so that judgment missing or judgment mistake occurs, and the detection accuracy and efficiency are further improved.
Preferably, the detection platform 21 is a disc structure, each detection installation groove 22 is an arc groove, and the detection installation grooves 22 are curved along the circumferential direction of the detection platform 21; wherein, as the detection platform 21 rotates around the first rotation direction 101, the distance between the detection installation groove 22 and the first axis gradually increases.
Specifically, by combining the structural characteristics of the detection mounting groove 22, the flowing vaginal secretion solution can be quickly covered on the detection card paper arranged in the detection mounting groove, so that the influence on the detection result caused by too low diffusion speed of the vaginal secretion solution in the detection mounting groove 22 is avoided; in addition, avoided the vaginal secretion solution after the color reaction can't arrange to waste liquid channel 42 from this detection mounting groove 22 fast for the combination appears accumulating and makes the color degree of depth that appears after diluting the color reaction by going into the vaginal secretion solution that liquid arc passageway 41 constantly arranges in this detection mounting groove 22, and then influences the accurate judgement of whole testing result.
Preferably, the support assembly 23 comprises, for example, a drive assembly for driving the output shaft 231 in rotation about a first axis along the first rotation direction 101; a first drainage bulge is arranged in the liquid inlet arc-shaped channel 41 and provided with a drainage inclined plane 411 which inclines towards the detection installation position, and the drainage inclined plane 411 is used for draining vaginal secretion solution in the liquid inlet arc-shaped channel 41 into the detection installation position; a first blocking bulge is arranged in the waste liquid channel 42, the first blocking bulge is provided with a blocking inclined plane 421 deviating from the detection installation position, and the blocking inclined plane 421 is used for blocking waste liquid in the waste liquid channel 42 from entering the detection assembly 20; wherein the waste liquid is a vaginal secretion solution which reacts with the detection assembly 20; the drainage slope 411 is inclined in the same direction as the blocking slope 421.
Specifically, in one embodiment, in combination with the actual detection process, during the process of starting the driving assembly, it can be understood that, during the starting phase, the detection platform 21 is accelerated to rotate, so that the vaginal secretion solution pre-placed in the liquid inlet arc-shaped channel 41 tends to move towards the direction away from the rotation direction, and in order to allow as much solution as possible to enter the corresponding detection installation groove 22 in a short time, the waste liquid channel 42, the plurality of detection installation grooves 22 and the liquid inlet arc-shaped channel 41 are sequentially arranged along the first rotation direction 101, so that under the action of the acceleration, the solution can rapidly enter the corresponding detection installation groove 22, and the centrifugal motion of the solution in the direction away from the first axis direction close to the inner wall of the liquid inlet arc-shaped channel 41 away from the detection installation groove 22 during the starting phase is avoided, thereby reducing the total amount of the vaginal secretion solution entering the plurality of detection installation grooves 22 and participating in the color reaction, and increasing the waste of the sample solution.
Further, in combination with the above specific example, since the drainage slope 411 exists, as much solution as possible can be drained to the corresponding detection installation groove 22, and since the drainage slope 411 and the blocking slope 421 are both inclined toward the same direction, it can be understood that, after the waste liquid enters the waste liquid channel 42, the waste liquid can be blocked from flowing back to the detection installation groove 22 by the blocking slope 421, and especially, in the end stage of the detection platform 21 being decelerated to stop, the backflow of the waste liquid is further effectively prevented.
Preferably, the liquid inlet arc-shaped channel 41 extends along a direction away from the first axis, and the channel width of the liquid inlet arc-shaped channel 41 is gradually reduced; and/or the waste channel 42 extends in a direction away from the first axis, the channel width of the waste channel 42 gradually increasing; and/or the liquid inlet arc-shaped channel 41 and the waste liquid channel 42 are bent towards the same direction, the channel depth of the liquid inlet arc-shaped channel 41 formed on the first detection surface 211 is H1, the channel depth of the waste liquid channel 42 formed on the first detection surface 211 is H2, and H1 is less than H2.
In combination with the actual detection process, it is conceivable that the evaporation rate of the vaginal secretion solution exposed to the air is positively correlated with the surface area of the solution, that is, the evaporation efficiency is higher when the surface area of the solution is larger, and thus, the evaporation amount of the vaginal secretion solution can be reduced to a certain extent by gradually reducing the width of the channel; in addition, especially, the plurality of detection installation grooves 22 far away from the first axis can generate color reaction with the vaginal secretion solution, so that the vaginal secretion solution is prevented from being evaporated or remained in the liquid inlet arc-shaped channel 41 to cause the waste of the vaginal secretion solution.
Preferably, the detection platform 21 is provided with a connecting shaft and a plurality of fan-shaped elastic plates 212 fixedly arranged around the connecting shaft, and each fan-shaped elastic plate 212 is provided with a detection installation position and a liquid inlet arc-shaped channel 41 and a waste liquid channel 42 which sandwich the detection installation position; the fan-shaped elastic plate 212 can deform along the axial direction of the connecting shaft, and the axial direction of the connecting shaft is overlapped with the first axial line; the support assembly 23 includes, for example, a disc support base and a magnet assembly 232. The disc supporting seat and the detection platform 21 are coaxially arranged, a planetary toothed belt 235, a driving gear 237 and a plurality of planetary gears 236 are arranged in the disc supporting seat, the plurality of planetary gears 236 are clamped between the planetary toothed belt 235 and the driving gear 237, and the number of teeth of the driving gear 237 is more than that of the planetary gears 236; the magnetic assembly 232 is disposed on at least one of the plurality of planetary gears 236, and the magnetic assembly 232 is configured to magnetically attract the magnetic metal member disposed on the side of the detecting platform 21 close to the supporting assembly 23, so that the fan-shaped elastic plate 212 moves toward the direction close to the magnetic assembly 232; when the magnetic assembly 232 is magnetically attracted and matched with the fan-shaped elastic plate 212, the distance formed between the first detection mounting groove and the disc support seat is smaller than the distance formed between the second detection mounting groove and the disc support seat.
In a specific example, a single vaginal secretion solution can be detected on each fan-shaped elastic plate 212, and a plurality of fan-shaped elastic plates 212 can correspondingly detect a plurality of vaginal secretions, so that the detection efficiency is greatly improved; in addition, the magnetic assembly 232 can be used to magnetically attract the testing platform 21, so that the end portion of the fan-shaped elastic plate 212 magnetically engaged therewith, which is close to the first axis, is located at a higher position, and the end portion away from the first axis is located at a lower position, i.e. the higher position corresponds to, for example, the distance formed between the first testing installation groove and the disc support seat, and the lower position corresponds to, for example, the distance formed between the second testing installation groove and the disc support seat. Therefore, in the process of rotating the detection platform 21, besides enabling the vaginal secretion solution to flow rapidly on the first detection surface 211 of the fan-shaped elastic plate 212 under the action of centrifugal force, the magnetic assembly 232 and the fan-shaped elastic plate 212 can be used for magnetically attracting and matching, so that the flow rate of the vaginal secretion solution is further improved, and the retention time of the vaginal secretion solution in the liquid inlet arc-shaped channel 41, the waste liquid channel 42 and the detection installation groove 22 is further avoided.
Furthermore, the rotation process of the detection platform 21 can be more stable and reliable through a gear meshing transmission mode.
Preferably, a limit plate 239 is disposed at one end of the disc support seat close to the detection platform 21, and the limit plate 239 extends toward a direction close to the center of the disc support seat to at least partially cover the planetary gear 236 at the corresponding position; a first height is formed between the planetary gear 236 and the limit plate 239; a first space 213 is formed between any two adjacent fan-shaped elastic plates 212, and the first space 213 can be used for the magnetic assembly 232 to pass through; during the process that the supporting component 23 drives the detecting platform 21 to rotate, the detecting device 100 is switched between a first detecting state and a second detecting state.
Specifically, on one hand, a limiting plate 239 is disposed at the top end of the disc support to prevent the planet toothed belt 235 connected to the magnetic assembly 232 from being separated from the disc support when the magnetic assembly 232 magnetically interacts with the detection platform 21, that is, the planet toothed belt 235 is separated from the driving gear 237, so that the detection platform 21 cannot be switched between the first detection state and the second detection state during the rotation process, for example, at least one of the fan-shaped elastic plates 212 is always in the deformation inclination state, and the flow rate of the vaginal secretion solution on the fan-shaped elastic plate 212 is too fast, it should be noted that the color reaction between the solution and the detection card paper is based on the sufficient reaction between the two, and if the solution rapidly flows through the surface of the detection card paper and cannot sufficiently react with the enzyme on the detection card paper, the detection result is inaccurate; on the other hand, by providing the first space 213 between any two adjacent fan-shaped elastic plates 212, each fan-shaped elastic plate 212 can be kept relatively independent as much as possible, and mutual interference can be avoided. In combination with the structural feature that the first space 213 can be used to pass through the magnetic assembly 232, the detection platform 21 can be switched between the first detection state and the second detection state without human intervention, so as to effectively regulate the diffusion rate of the vaginal secretion solution.
Preferably, the magnetic assembly 232 is provided with magnetic protruding blocks 2321 protruding towards the detection platform 21, and the magnetic protruding blocks 2321 are matched with the planetary gears 236 one by one; an adjusting distance with variable size is formed between the magnetic convex block 2321 and the detection platform 21; wherein, the magnetic radius of the magnetic bump 2321 is smaller than the maximum value of the adjusting distance; in the first detection state, the magnetic protrusions 2321 are magnetically attracted to and engaged with the corresponding fan-shaped elastic plate 212, the top end surface of the planetary gear 236 abuts against the bottom end surface of the limiting plate 239, and the fan-shaped elastic plate 212 deforms; in the second detection state, the magnetic protrusions 2321 magnetically engage with the corresponding sector-shaped elastic plate 212, the top end surface and the bottom end surface form a first height, and the sector-shaped elastic plate 212 is horizontally disposed. Further improves the effect of effectively regulating the diffusion rate of the vaginal secretion solution so as to improve the detection efficiency.
Preferably, the disc support base includes, for example, a support base plate 233 and a circular ring rail 234. At least one circular arc protruding piece 238 is arranged on one side of the supporting base plate 233 close to the detection platform 21, and the circular arc protruding piece 238 is used for lifting the corresponding planetary gear 236 to a second height in a direction close to the limit plate 239; the circular ring track 234 is provided with a planetary gear belt 235, the circular ring track 234 surrounds the outer edge of the support base plate 233, and the circular ring track 234 and the support base plate 233 surround to form a transmission space for accommodating the driving gear 237 and the plurality of planetary gears 236; wherein, the first height is D1, and the radius of magnetism is D, and the second height is D2, and the regulation distance is D3, and the maximum value of regulation distance is D3 max ,D2≤D1<D3 max ,D3 max -D2≤D<D3 max . The detection platform 21 can be flexibly switched between the first detection state and the second detection state in the rotation process without human interference, and the overall detection efficiency is improved. In order to facilitate the process of making the planetary gear 236 perform planetary rotation around the driving gear 237, the planetary gear 236 can be smoothly matched and connected with the arc-shaped protrusion 238, and the arc-shaped protrusion 238 is prevented from being abutted and locked with the planetary gear 236, so that the arc-shaped transition surface 2361 is arranged on the outer edge of the bottom end surface of the planetary gear 236, so that the arc-shaped protrusion 238 can stably lift the planetary gear 236 matched with the arc-shaped protrusion 238, and further the distance between the magnetic protrusion 2321 and the detection platform 21 is changed. During the rotation of the testing platform 21, the circular arc protrusion 238 is also separated from the planetary gear 236, so as to bring the planetary gear 236 back into contact with the supporting base plate 233.
Preferably, the top end of the detection seat 10 is provided with a movable sliding rail 12, and the detection device 100 comprises a color identification component 30 arranged on the movable sliding rail 12; the color recognition component 30 includes, for example, a transmission body, a distance sensor, a color recognition sensor, and a display component. The transmission main body is connected with the movable slide rail 12 in a sliding way, and an electric control component is arranged in the transmission main body; the distance sensor is arranged at one end of the transmission main body, which is far away from the movable slide rail 12, and is arranged opposite to the detection installation part; the color recognition sensor and the distance sensor are arranged in parallel on the transmission main body, and the color recognition sensor is used for recognizing the color of a detection piece arranged at the detection installation position and acquiring a color signal; when the transmission main body moves along the movable slide rail 12, the distance sensor acquires a long signal and a short signal corresponding to the detection platform 21; the long signal corresponds to the positions of the plurality of detection mounting grooves 22, and the short signal corresponds to the position of the isolation convex structure 25; the display assembly is connected to the test socket 10 and is used for converting the long signal, the short signal and the color signal into visual information.
In one embodiment, the detection process may be divided into three detection steps, wherein the first detection step is to rotate the detection platform 21 so that the vaginal secretion solution can perform a sufficient color reaction with the corresponding detection card paper; the second detection step is to control the color recognition component 30 to move on the movable slide rail 12 when the detection platform 21 stops rotating and stops at the first position, so as to recognize the color of the multiple detection jams in the detection mounting slots 22 below the color recognition component and generate color signals corresponding to the color; the third detection step is to transmit the generated color signal to the display module, which correlates the color signal with the long signal and the short signal and converts it into a visual signal. Specifically, a long signal corresponds to the distance measured by the distance sensor from the detection mounting groove 22 directly below the distance sensor, and a short signal corresponds to the distance measured by the distance sensor from the isolation bump structure 25 directly below the distance sensor.
Furthermore, the initial position of the color identification component 30 is directly above the center of the circle corresponding to the detection platform 21, and the final position reaches the boundary of the detection platform 21, so that the color identification component 30 moves linearly in the movable slide rail 12. It should be noted that, when the color identification sensor performs color sampling on the isolation convex structure 25, since the isolation convex structure 25 does not participate in the color reaction, no color change occurs; when any one of the detection jams shows negative, that is, no color change occurs, and if the colors of the detection jams are similar to each other, it is difficult for the color recognition sensor to distinguish the detection jams. Therefore, the long signal and the color signal can be associated, for example, in the moving process, the distance sensor acquires a long signal and a short signal, and correspondingly, the color identification sensor also acquires two color signals, so that the color signal at the moment is associated with the long signal while the long signal is acquired, and the color signal corresponding to the short signal is not fed back, so that when the color signal is converted into the visual information, a corresponding blank or a specific number or a specific figure appears on the display screen of the display component for the color signal of the short signal, and the description is omitted here. And the color signal corresponding to the long signal can be converted into the color of the actual reaction, etc.
It should be noted that the visual information is a signal visually visible or distinguishable by an operator, such as a color, a pattern, or a number.
Therefore, the color recognition component 30 can be used for directly distinguishing colors of the detected paper jam instead of human eyes, so that the accuracy of detection result judgment is improved.
Preferably, the detecting device 100 further includes, for example, a nozzle assembly and a reagent placing area, specifically, the nozzle assembly includes a nozzle 102 and an elastic connector 103, the nozzle 102 is connected to the top position of the detecting seat 10 through the elastic connector 103, and the nozzle 102 can be used for sucking and storing the sample solution in the reagent tube 104, and injecting the sample solution into the liquid inlet arc-shaped channel 41; and the reagent placement area is used for placing the reagent cartridge.
Further, to ensure that the detection platform 21 is rotated, the vaginal secretion solution or waste liquid is prevented from flying out of the detection device 100, which causes a sanitary safety problem. Can make detection device 100 for example still include waste liquid collection piece 24, specifically, waste liquid collection piece 24 is the circular structure that flexible material made, is equipped with the storage space that is used for saving vaginal secretion solution and waste liquid in and the inlet that communicates with storage space in, and waste liquid collection piece 24 joint is to detection platform 21's outward flange position to storage space realizes switching on with income liquid arc-shaped channel 41 and waste liquid channel 42 through the inlet. The waste liquid collecting member 24 may be, for example, a disposable plastic bag, which is easily replaced.
Example two:
fig. 14 is a schematic flow chart of a detection method according to a second embodiment of the present invention. The detection method is applied to the detection device 100 according to the first embodiment.
With reference to fig. 1 to fig. 13, in detail, the detection method includes:
s1, preparing a vaginal secretion solution, and placing the vaginal secretion solution in a corresponding reagent tube 104 to keep stirring for a first preset time;
s2, placing a plurality of detection pieces in each first detection mounting groove and each second detection mounting groove;
s3, sucking a first component of the stirred vaginal secretion solution by using the suction nozzle assembly and injecting the first component to a position, close to the output shaft 231, of the first detection mounting groove;
s4, controlling a driving assembly in the supporting assembly 23 to drive the detection platform 21 to rotate around a second direction for a second preset time so that the vaginal secretion solution enters each corresponding detection installation position from the liquid inlet arc-shaped channel 41;
s5, when the rotation time of the detection platform 21 meets second preset time, controlling the detection platform 21 to stop at a first position through the driving assembly;
s6, controlling the color recognition component 30 to move on the movable sliding rail 12 to obtain a color signal of the same vaginal secretion solution participating in a color development reaction;
s7, converting the color signal into a visual signal through a signal converter electrically connected with the color recognition component 30;
s8, displaying the visual signal on a display screen through a display component of the detection device 100;
and S9, judging the bacterial condition in the vaginal secretion according to the display result on the display screen.
When the detection platform 21 is at the first position, the projection of the color recognition component 30 in the vertical direction falls between the liquid inlet arc-shaped channel 41 and the waste liquid channel 42, and corresponds to the positions of the plurality of detection installation grooves 22.
Specifically, this embodiment can achieve the technical effect corresponding to any one of the technical solutions in the first embodiment, and details are not described here.
Although the present invention is disclosed above, the present invention is not limited thereto. Various changes and modifications may be effected therein by one skilled in the art without departing from the spirit and scope of the invention as defined in the appended claims.

Claims (7)

1. A test device for testing vaginal secretions, comprising:
the detection seat is provided with a first installation space;
the detection assembly is arranged in the first installation space and comprises:
a support assembly provided with an output shaft rotating about a first axis;
the detection platform is matched with the output shaft to be rotationally connected to the support assembly; one side of the detection platform, which is far away from the support component, is a first detection surface;
the detection mounting position is arranged on the first detection surface; the detection installation position is provided with a plurality of detection installation grooves which are sequentially arranged along a first direction, an isolation bulge structure is arranged between any two adjacent detection installation grooves, at least one first detection installation groove and at least one second detection installation groove exist in the detection installation grooves, a first distance is formed between the first detection installation groove and the first axis, and a second distance which is larger than the first distance is formed between the second detection installation groove and the first axis; the detection installation position is used for placing various detection pieces, and the detection pieces comprise detection paper jam;
the liquid inlet arc-shaped channel extends along the first direction, is arranged at the first end of the detection mounting position and is communicated with the detection mounting grooves;
the waste liquid channel extends along the first direction, is arranged at a second end of the detection mounting position, is opposite to the first end, and is communicated with the detection mounting grooves; when the output shaft drives the detection platform to rotate along a first rotating direction, vaginal secretion solution in the liquid inlet arc-shaped channel sequentially passes through the liquid inlet arc-shaped channel, the detection assembly and the waste liquid channel; go into liquid arc passageway with the waste liquid passageway is towards same direction bending, just it is in to go into liquid arc passageway the passageway degree of depth that forms on the first detection face is H1, the waste liquid passageway is in the passageway degree of depth that forms on the first detection face is H2, H1 < H2
The support assembly includes:
a drive assembly for driving the output shaft to rotate about the first axis in the first rotational direction;
a first drainage bulge is arranged in the liquid inlet arc-shaped channel, a drainage inclined plane which inclines towards the detection installation position is arranged on the first drainage bulge, and the drainage inclined plane is used for draining the vaginal secretion solution in the liquid inlet arc-shaped channel into the detection installation position;
a first blocking bulge is arranged in the waste liquid channel, a blocking inclined plane deviating from the detection installation position is arranged on the first blocking bulge, and the blocking inclined plane is used for blocking waste liquid in the waste liquid channel from entering the detection assembly; wherein the waste liquid is the solution after the vaginal secretion solution reacts with the detection assembly; the drainage inclined plane and the blocking inclined plane incline towards the same direction;
the top end of the detection seat is provided with a movable sliding rail; detection device is including locating the colour identification component of removal slide rail, the colour identification component includes:
the transmission main body is connected with the movable slide rail in a sliding manner, and an electric control assembly is arranged in the transmission main body;
the distance sensor is arranged at one end of the transmission main body, which is far away from the movable slide rail, and is arranged opposite to the detection installation part;
the color recognition sensor is arranged in the transmission main body in parallel with the distance sensor and is used for recognizing the color of a detection piece arranged at the detection mounting position and acquiring a color signal; when the transmission main body moves along the movable sliding rail, the distance sensor acquires a long signal and a short signal corresponding to the detection platform; the long signal corresponds to the positions of the plurality of detection mounting grooves; the short signal corresponds to the isolation bump structure;
and the display component is connected to the detection seat and is used for converting the long signal, the short signal and the color signal into visual information.
2. The detection apparatus according to claim 1,
the detection platform is of a disc structure, each detection mounting groove is an arc groove, and the detection mounting grooves are bent along the circumferential direction of the detection platform;
wherein, as the detection platform rotates around the first rotation direction, the distance between the detection installation groove and the first axis gradually increases.
3. The detection apparatus according to claim 1,
the liquid inlet arc-shaped channel extends along the direction far away from the first axis, and the width of the liquid inlet arc-shaped channel is gradually reduced; and/or the presence of a gas in the gas,
the waste liquid channel extends along a direction away from the first axis, and the channel width of the waste liquid channel is gradually increased.
4. The detection apparatus according to claim 2,
the detection platform is provided with a connecting shaft and a plurality of fan-shaped elastic plates fixedly arranged around the connecting shaft, and each fan-shaped elastic plate is provided with one detection installation position, one liquid inlet arc-shaped channel and one waste liquid channel which are used for clamping the detection installation position; the fan-shaped elastic plate can deform along the axial direction of the connecting shaft, and the axial line of the connecting shaft is superposed with the first axial line;
the support assembly includes:
the disc supporting seat is coaxially arranged with the detection platform, a planet toothed belt, a driving gear and a plurality of planet gears are arranged in the disc supporting seat, the planet gears are clamped between the planet toothed belt and the driving gear, and the number of teeth of the driving gear is more than that of the planet gears;
the magnetic assembly is arranged on at least one of the planetary gears and used for magnetically attracting the magnetic metal piece arranged on one side of the detection platform close to the support assembly so as to enable the fan-shaped elastic plate to move towards the direction close to the magnetic assembly;
when the magnetic assembly is matched with the fan-shaped elastic plate in a magnetic attraction mode, the distance formed between the first detection mounting groove and the disc supporting seat is smaller than the distance formed between the second detection mounting groove and the disc supporting seat.
5. The detection apparatus according to claim 4,
a limiting plate is arranged at one end, close to the detection platform, of the disc supporting seat, and the limiting plate extends towards the direction close to the circle center of the disc supporting seat so as to at least partially cover the planetary gear at the corresponding position; a first height is formed between the planetary gear and the limiting plate;
a first interval is formed between any two adjacent fan-shaped elastic plates, and the first interval can be used for the magnetic assembly to pass through;
in the process that the supporting assembly drives the detection platform to rotate, the detection device is switched between a first detection state and a second detection state.
6. The detection apparatus according to claim 5,
the magnetic assembly is provided with magnetic protruding blocks protruding towards the detection platform, and the magnetic protruding blocks are matched with the planetary gears one by one; and an adjusting distance with variable size is formed between the magnetic convex block and the detection platform; wherein the magnetic radius of the magnetic convex block is smaller than the maximum value of the adjusting distance;
when the planetary gear is in the first detection state, the magnetic convex blocks are matched with the corresponding fan-shaped elastic plates in a magnetic attraction mode, the top end face of the planetary gear is abutted to the bottom end face of the limiting plate, and the fan-shaped elastic plates deform; when the second detection state is detected, the magnetic convex block is in magnetic fit with the corresponding fan-shaped elastic plate, the top end face and the bottom end face form the first height, and the fan-shaped elastic plate is horizontally arranged.
7. The detecting device according to claim 6, wherein said disc support base comprises:
the supporting bottom plate is provided with at least one arc-shaped protruding piece at one side close to the detection platform, and the arc-shaped protruding piece is used for lifting the corresponding planetary gear to a second height in the direction close to the limiting plate;
the circular ring track is provided with the planet toothed belt, the circular ring track surrounds the outer edge of the support base plate, a transmission space is formed by the circular ring track and the support base plate in a surrounding mode, and the transmission space is used for accommodating the driving gear and the plurality of planet gears;
wherein, first height is D1, the radius of inhaling is D, the second height is D2, adjusting distance is D3, adjusting distance's maximum value is D3 max ,D2≤D1<D3 max ,D3 max -D2≤D<D3 max
CN202210941607.4A 2022-08-08 2022-08-08 Detection device for detecting vaginal secretion Active CN114989961B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210941607.4A CN114989961B (en) 2022-08-08 2022-08-08 Detection device for detecting vaginal secretion

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202210941607.4A CN114989961B (en) 2022-08-08 2022-08-08 Detection device for detecting vaginal secretion

Publications (2)

Publication Number Publication Date
CN114989961A CN114989961A (en) 2022-09-02
CN114989961B true CN114989961B (en) 2022-11-22

Family

ID=83022925

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202210941607.4A Active CN114989961B (en) 2022-08-08 2022-08-08 Detection device for detecting vaginal secretion

Country Status (1)

Country Link
CN (1) CN114989961B (en)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2793883A1 (en) * 1999-05-19 2000-11-24 Hemery Fernand Moutete Device for analyzing body secretions from the urogenital region, e.g. for diagnosis of lower urogenital infections, comprising absorbent support including systems for in situ analysis and visualization of results
US6921647B2 (en) * 2001-07-19 2005-07-26 Common Sense Ltd. Secretion-monitoring article
CN101852738B (en) * 2010-04-20 2012-02-15 珠海市丽拓发展有限公司 Colpitis detector
CN205056043U (en) * 2015-08-24 2016-03-02 杭州霆科生物科技有限公司 A disc micro -fluidic chip for in batches quick examination of pesticide residue
CN107328945A (en) * 2017-07-28 2017-11-07 珠海迪尔医疗设备研究院有限公司 A kind of detection retracting device of automatic bacterial vaginosis detector
CN208308841U (en) * 2018-04-19 2019-01-01 河北生命原点生物科技有限公司 A kind of novel cancer cell detection kit
CN112986148A (en) * 2019-12-12 2021-06-18 杭州微策生物技术股份有限公司 Biological fluid detection device, detection system and detection method
CN211668812U (en) * 2020-03-10 2020-10-13 四川省兴冶岩土工程检测有限责任公司 Ground detection sampling device
CN114324948A (en) * 2020-09-30 2022-04-12 深圳市瑞图生物技术有限公司 Advance appearance subassembly and gynaecology's secretion detection device
CN114199787A (en) * 2021-12-01 2022-03-18 重庆建峰新材料有限责任公司 COD detection device for wastewater treatment

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
***分泌物常规检测与五联检的联合应用分析;闫莉梅;《淮海医药》;20130930;第31卷(第05期);第434-435页 *

Also Published As

Publication number Publication date
CN114989961A (en) 2022-09-02

Similar Documents

Publication Publication Date Title
US11579158B2 (en) Automatic human urine detection system
CN114989961B (en) Detection device for detecting vaginal secretion
WO2006134815A1 (en) Tissue trapping apparatus, treatment instrument for endoscope, and endoscope
EP2042853A1 (en) Analyzer and use thereof
US20220178956A1 (en) Fully-automatic excrement analyzer
EP1074610A1 (en) System for analyzing images produced by bacterial reactions
WO2020088474A1 (en) Porous sample feeding cell counter and counting method
CN103308376B (en) Blood collection uniform mixer
JP2014021112A (en) Microfluidic structure, microfluidic device having the same and method of controlling microfluidic device
CN112756018A (en) Micro-fluidic chip and in-vitro detection system
CN106405131A (en) Cell and protein combined analysis device and combined analysis method
CN201990676U (en) Automatic bacterial colony recognition device
CN110646608A (en) Carousel formula ally oneself with more and examine device and system
CN101799478B (en) Reagent tray device for automatic immunity analyzer
CN106872684B (en) Integrated reagent set parallel processing reaction unit
CN209041750U (en) Valve gear
US20170157615A1 (en) Mating adaptor for coupling a point-of-care diagnostic cartridge to a computing device
KR100511628B1 (en) System and method for interpreting microorganisms in air
WO2021235015A1 (en) Automatic analyzer and assembly assistance system thereof
EP1368635B1 (en) Apparatus and method for processing and testing a biological specimen
JP3758423B2 (en) incubator
CN211179851U (en) Carousel formula ally oneself with more and examine device and system
CN103543102A (en) Test device and control method thereof
CN209296421U (en) A kind of full-automatic histocyte coloring system
CN220158281U (en) Urinal urine receiving mechanism

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant