CN114984379A - High-pressure driven needleless injection device - Google Patents
High-pressure driven needleless injection device Download PDFInfo
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- CN114984379A CN114984379A CN202210543604.5A CN202210543604A CN114984379A CN 114984379 A CN114984379 A CN 114984379A CN 202210543604 A CN202210543604 A CN 202210543604A CN 114984379 A CN114984379 A CN 114984379A
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- 238000002347 injection Methods 0.000 title claims abstract description 122
- 239000007924 injection Substances 0.000 title claims abstract description 122
- 239000007788 liquid Substances 0.000 claims abstract description 92
- 238000010304 firing Methods 0.000 claims abstract description 50
- 239000003814 drug Substances 0.000 claims abstract description 45
- 230000007246 mechanism Effects 0.000 claims abstract description 30
- 238000007789 sealing Methods 0.000 claims description 63
- 241001270131 Agaricus moelleri Species 0.000 claims description 16
- 238000004891 communication Methods 0.000 claims description 16
- 239000012530 fluid Substances 0.000 claims description 2
- 230000005540 biological transmission Effects 0.000 claims 1
- 230000002035 prolonged effect Effects 0.000 abstract description 7
- 230000004044 response Effects 0.000 abstract description 4
- 239000007789 gas Substances 0.000 description 20
- 238000000034 method Methods 0.000 description 13
- 230000008569 process Effects 0.000 description 11
- 230000009286 beneficial effect Effects 0.000 description 9
- 230000000694 effects Effects 0.000 description 8
- 230000000149 penetrating effect Effects 0.000 description 7
- 230000001276 controlling effect Effects 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 239000011148 porous material Substances 0.000 description 4
- 238000005213 imbibition Methods 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 210000003491 skin Anatomy 0.000 description 3
- 230000008859 change Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 238000009434 installation Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 229910052757 nitrogen Inorganic materials 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 210000004872 soft tissue Anatomy 0.000 description 2
- 238000007920 subcutaneous administration Methods 0.000 description 2
- 210000003437 trachea Anatomy 0.000 description 2
- 230000004075 alteration Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 208000002925 dental caries Diseases 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 230000003116 impacting effect Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 238000010254 subcutaneous injection Methods 0.000 description 1
- 239000007929 subcutaneous injection Substances 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
- A61M5/3007—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules with specially designed jet passages at the injector's distal end
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3128—Incorporating one-way valves, e.g. pressure-relief or non-return valves
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The invention discloses a high-pressure driven needle-free injection device which is used for delivering external liquid medicine to an intradermal space of an individual and comprises a cylinder body, an injection mechanism and a high-pressure driving assembly arranged outside the cylinder body. One end of the cylinder body is connected with a first end cover, and the other end of the cylinder body is connected with a second end cover; the injection mechanism is partially arranged in a space defined by the cylinder body, the first end cover and the second end cover and comprises a piston and a firing pin, the firing pin is nested in the piston, and the piston is nested in the cylinder body; the high-pressure driving assembly is communicated to the interior of the cylinder body and provides driving force for the injection mechanism. The high-pressure driving piston and the firing pin are used for efficiently and quickly driving and injecting liquid medicine in the device from the inside to the outside of the device, so that the needle-free injection device has higher flexibility and higher response speed compared with a traditional spring-type needle-free injector, and the service life of the injection device is greatly prolonged.
Description
Technical Field
The invention relates to the field of medical drug injection, in particular to a high-pressure driving needle-free injection device.
Background
Traditional syringe needle syringe carries out the medicine injection through the syringe needle in vitro, and this kind of mode is passed through the stainless steel syringe needle and is injected the medicine to internal, and the syringe needle causes the damage to human tissue easily, and a large amount of disposable syringe needles abandonment after using can cause great pollution to the environment simultaneously.
The needleless injector generates driving force through the driving device, the piston rod is pushed at high speed, so that liquid stored in the container obtains larger kinetic energy in a short time, and then is ejected out of the jet flow pore at high speed, and is dispersed and distributed at a specific position after piercing the skin, and administration is realized.
The spring type needleless injector in the prior art is widely applied in the market due to simple structure and low cost, but the rigidity coefficient of the spring is reduced after the spring type needleless injector is used for a long time, so that the flexibility of the spring type needleless injector is poor, continuous work cannot be realized, and the service life of the injector is limited. Therefore, it is desirable to provide a high pressure driven needleless injection device to solve the problems of the prior art.
Disclosure of Invention
The embodiment of the application provides a high-pressure driving needleless injection device to solve the technical problems of poor flexibility and short service life of a drug injector in the prior art.
In order to solve the technical problem, the embodiment of the application provides a high-pressure driving needle-free injection device for delivering external liquid medicine to an intradermal space of an individual, which comprises a cylinder body, an injection mechanism and a high-pressure driving assembly arranged outside the cylinder body, wherein one end of the cylinder body is connected with a first end cover, and the other end of the cylinder body is connected with a second end cover; the injection mechanism is partially arranged in a space enclosed by the cylinder, the first end cover and the second end cover and comprises a piston and a firing pin, the firing pin is nested in the piston, and the piston is nested in the cylinder; the high-pressure driving assembly is communicated with the interior of the cylinder body and provides driving force for the injection mechanism.
By adopting the technical scheme provided by the embodiment of the application, the method at least has the following technical effects:
the injection mechanism is arranged in a space defined by the first end cover, the second end cover and the cylinder body, is externally communicated to the inside of the cylinder body through the high-pressure driving assembly, and drives the piston and the firing pin in a high-pressure driving mode to efficiently and quickly inject liquid medicine in the device, so that the needle-free injection device has higher flexibility and higher response speed compared with the traditional spring-type needle-free injector, and the service life of the injection device is greatly prolonged.
Further, a first sealing ring and a third sealing ring are arranged between the cylinder body and the piston, a fourth sealing ring is arranged between the first end cover and the cylinder body, a first cavity is formed between the piston and the first end cover through the third sealing ring and the fourth sealing ring inside the cylinder body, and a second cavity is formed between the cylinder body and the piston in a sealing mode through the first sealing ring and the third sealing ring.
The beneficial effect of adopting the further scheme is that: through the multi-sealing ring, the cylinder body, the piston and the firing pin are divided into a plurality of sealing cavities, so that a stroke space is provided for the high-pressure driving device, and a strong high-pressure driving effect is realized.
Further, the second end cover comprises a cover body and a through column penetrating the center of the cover body, a through hole is formed in the center of the through column, and the firing pin can be inserted into the through hole to reciprocate; a second sealing ring is arranged between the firing pin and the through column, when one end of the firing pin moves in the through hole, a liquid suction cavity is formed between the other end of the firing pin and the through column, and the liquid suction cavity is used for absorbing and containing external liquid medicine; a third cavity is formed among the piston, the striker and the through column, a pressure relief hole is formed in the piston, and the third cavity is communicated with the second cavity through the pressure relief hole.
The beneficial effect of adopting the above further scheme is: through the through column with the through hole arranged on the second end cover, when the firing pin reciprocates in the through hole, a liquid suction cavity with a negative pressure adsorption effect is formed in the through hole, external liquid medicine can be adsorbed into the liquid suction cavity, and the piston and the firing pin generate axial motion under high-pressure impact to drive the liquid medicine to be ejected outwards; the pressure relief hole is arranged in the structure of the invention to communicate the third cavity with the second cavity, so that high-pressure gas in the third cavity can be discharged into the second cavity, the balance of internal and external pressure is kept, the service life of the device is prolonged, and the device is prevented from being damaged by overlarge internal pressure of the third cavity.
Further, a sealing plug is coaxially arranged at one end of the piston and the firing pin, and a stroke gap is formed between the sealing plug and the firing pin.
The beneficial effect of adopting the further scheme is that: by arranging the sealing plug, on one hand, the first cavity is separated from the third cavity, so that pressure relief is avoided; on the other hand, a stroke gap is formed between the sealing plug and the firing pin, when the high-pressure gas drives the piston to move rightwards through the first cavity, the sealing plug is contacted with the firing pin after a section of high-speed stroke and then moves rightwards along the axis together, the time required by the liquid medicine to reach the peak speed can be reduced, and the capability of the jet flow penetrating through the skin soft tissue is improved.
Further, at least one guide ring is arranged between the piston and the cylinder, and at least one guide ring is arranged between the firing pin and the through column.
The beneficial effect of adopting the further scheme is that: the guide rings are arranged between the piston and the cylinder body and between the firing pin and the through column, so that the damage caused by mutual contact friction between the piston and the cylinder body and between the firing pin and the through column can be avoided on the first aspect, and the function of correcting the coaxiality between the cylinder body and the piston and between the firing pin and the second end cover can be played on the second aspect, so that the sealing and injection effects of the device are prevented from being influenced by the mutual eccentricity of the cylinder body, the piston, the firing pin and the through column.
Furthermore, a first connecting channel and a second connecting channel are arranged on the cylinder body, one end of the high-pressure driving assembly is communicated with the first cavity through the first connecting channel, the other end of the high-pressure driving assembly is communicated with the second cavity through the second connecting channel, and the piston is controlled to drive the firing pin to perform reciprocating stroke motion in the through column by controlling the pressure in the first cavity and the pressure in the second cavity.
The beneficial effect of adopting the further scheme is that: through set up a plurality of connecting channel on the cylinder body for inside high-pressure gas in the outside high pressure drive air supply can get into the different cavitys of device, thereby realizes controlling piston and firing pin through high-pressure gas and carries out quick stroke motion.
Further, the injection mechanism further comprises a nozzle detachably connected to the outer side of the second end cap.
The beneficial effect of adopting the above further scheme is: the injection mechanism is provided with the nozzle which can be conveniently detachably connected with the second end cover so as to change the jet impact speed and improve the injection efficiency.
Further, the nozzle is a flat-top injection nozzle or a conical straight injection nozzle.
The beneficial effect of adopting the further scheme is that: the flat-top injection nozzle and the conical straight injection nozzle are convenient to process and realize mass production, and have strong jet penetration capability, high utilization rate and strong controllability.
Furthermore, the injection mechanism further comprises a liquid storage container, a communication hole is formed in the second end cover, external liquid medicine is conveyed into the communication hole by the liquid storage container, the communication hole is connected to the liquid suction cavity, and a one-way valve is arranged between the liquid storage container and the liquid suction cavity.
The beneficial effect of adopting the further scheme is that: the liquid storage container is arranged to provide a space for storing liquid medicine for the injection mechanism, and the liquid medicine flows into the second end cover through the communicating holeLiquid suction cavityIn, and set up the check valve in the intercommunicating pore to the flow direction of restriction liquid medicine flows to the imbibition chamber from the receiver promptly, thereby has avoided the condition of liquid medicine refluence to take place, influences the injection effect.
Further, the high-pressure driving assembly comprises a high-pressure air source and a reversing valve, and a throttle valve is arranged between the high-pressure air source and the reversing valve.
The beneficial effect of adopting the further scheme is that: the high-pressure gas is used as a power source of the driving assembly, the cost is low, the environment is protected, the reliability is high, the throttle valve is arranged between the high-pressure gas source and the reversing valve, the pressure can be conveniently adjusted, the throttling and the pressure reduction are realized, and the reliability of the injection loading process is enhanced.
Additional aspects and advantages of the present application will be set forth in part in the description which follows and, in part, will be obvious from the description, or may be learned by practice of the present application.
Drawings
Fig. 1 is a schematic structural view of a high pressure driven needleless injection device provided by one embodiment of the present invention;
FIG. 2 is a schematic view of the initial state of the high pressure actuated needleless injection apparatus provided in section A-A of FIG. 1 in the embodiment
FIG. 3 is a schematic view of the section A-A in the embodiment of FIG. 1 illustrating the critical injection state of the high pressure-actuated needle-free injection device;
FIG. 4 is a schematic view of the section A-A in the embodiment of FIG. 1 showing the completion of injection in the high pressure-actuated needle-free injection device;
FIG. 5 is a schematic cross-sectional view of a three-dimensional structure of a straight cone injection nozzle according to one embodiment of the present invention;
FIG. 6 is a schematic cross-sectional view of a three-dimensional structure of a flat-top injection nozzle provided in accordance with another embodiment of the present invention;
fig. 7 is a cross-sectional view of another embodiment of the high pressure actuated needleless injection device of the present invention in an initial state;
fig. 8 is a cross-sectional view of a high pressure driven needle-free injection device according to another embodiment of the present invention;
fig. 9 is a schematic perspective view of a second end cap in embodiment 1 of the present invention.
Fig. 10 is a schematic perspective view of a second end cap in embodiment 2 of the present invention.
In the figure:
1. a first end cap; 2. a first connecting channel; 3. a first guide ring; 4. a pressure relief vent; 5. a diverter valve; 6. a high pressure gas source; 7. a throttle valve; 8. a cylinder body; 9. a piston; 10. a second connecting channel; 11. a first seal ring; 12. a second guide ring; 13. a striker; 14. a second end cap; 141. a cover body; 1411. a communicating hole; 142. passing through a column; 1421. a through hole; 1422. a first through cylinder; 1423. a second through-cylinder; 15. a nozzle; 151. a frustum; 152. perforating; 153. a hollow cone; 154. connecting holes; 155. bolt holes; 156. connecting columns; 157. a liquid channel; 16. a liquid suction chamber; 17. a one-way valve; 18. a reservoir; 19. a third guide ring; 20. a fourth guide ring; 21. a second seal ring; 22. a third cavity; 23. a second cavity; 24. a third seal ring; 25. sealing and plugging; 26. a first cavity; 27. a fourth seal ring; 28. a fixing member; 29. and a fifth sealing ring.
Detailed Description
Reference will now be made in detail to embodiments of the present application, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the drawings are exemplary only for the purpose of explaining the present application and are not to be construed as limiting the present application.
In the description of the present application, it should be understood that the positional descriptions referred to, for example, the directions or positional relationships indicated by upper, lower, front, rear, left, right, etc., are based on the directions or positional relationships shown in the drawings, and are only for convenience of description and simplification of the description, but do not indicate or imply that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and thus, should not be construed as limiting the present application.
In the description of the present application, several means are one or more, and the above, below, within and the like are understood to include the present numbers. The description to first, second, etc. is only for the purpose of distinguishing technical features, and should not be interpreted as indicating or implying a relative importance or implicitly indicating the number of technical features indicated or implicitly indicating the precedence of technical features indicated.
In the description of the present application, unless otherwise expressly limited, terms such as set, mounted, connected and the like should be construed broadly, and those skilled in the art can reasonably determine the specific meaning of the terms in the present application by combining the detailed contents of the technical solutions.
In the description of the present application, reference to the description of the terms "one embodiment," "some embodiments," "an illustrative embodiment," "an example," "a specific example," or "some examples," etc., means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the present application. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The embodiment of the application solves the problems of low flexibility, low response speed and poor service life of the traditional spring type needleless injector in the prior art by providing the high-pressure driving needleless injector. In order to solve the above technical problems and to provide the design solution, the following detailed description of the technical solution of the present application is made through the accompanying drawings and the specific embodiments, and it should be understood that the specific features in the embodiments and the examples of the present application are detailed descriptions of the technical solution of the present application, and are not limitations of the technical solution of the present application, and the technical features in the embodiments and the examples of the present application may be combined with each other without conflict.
Referring to fig. 1 and fig. 2, fig. 1 is a schematic perspective view of a high-pressure-driven needleless injection device according to an embodiment of the present invention, and fig. 2 is a schematic sectional view taken along line a-a in fig. 1, as shown in the drawings:
a high-pressure driving needle-free injection device is used for delivering external liquid medicine to an intradermal space of an individual and comprises a cylinder body 8, an injection mechanism and a high-pressure driving assembly arranged outside the cylinder body 8, wherein the left end of the cylinder body 8 is connected with a first end cover 1, and the right end of the cylinder body 8 is connected with a second end cover 14; the injection mechanism is partially arranged in a space surrounded by the cylinder 8, the first end cover 1 and the second end cover 14 and comprises a piston 9 and a firing pin 13, wherein the firing pin 13 is nested in the piston 9, and the piston 9 is nested in the cylinder 8; the high pressure drive assembly communicates to the interior of the cylinder 8 and provides the drive force for the injection mechanism. Because the injection mechanism is arranged in the space enclosed by the first end cover 1, the second end cover 14 and the cylinder body 8, the piston 9 and the firing pin 13 are driven by high pressure to inject the liquid medicine in the device from the inside to the outside of the device efficiently and quickly, the needleless injection device has higher flexibility and faster response speed compared with the traditional spring type needleless injector, and the service life of the injection device is greatly prolonged.
The high-pressure driving needle-free injection device provided by the embodiment of the invention completes the subcutaneous injection of the liquid medicine based on the high-pressure jet penetration principle, namely, the firing pin is driven by the internal driving system of the needle-free injection device, so that the liquid medicine in the needle-free injection device is pushed to form a superfine liquid medicine column through the micropores, the liquid medicine instantly penetrates through the epidermis of an individual to reach the subcutaneous part, and the liquid medicine is dispersed at a certain depth of the subcutaneous part and then is absorbed.
Fig. 2 is a schematic structural diagram of an injection initial state of one embodiment of the high-pressure-driven needleless injection device of the present invention, in some embodiments, the first end cap 1 is connected to the cylinder 8 through a fixing member 28, in order to facilitate the fixing connection, the fixing member is a bolt, a counter bore is provided on the first end cap 1, one end of the cylinder 8 connects the first end cap 1 to the cylinder 8 through a hexagon socket head cap bolt, and a fourth sealing ring 27 is provided between the cylinder 8 and the first end cap 1, so that a sealing configuration is formed between the cylinder 8 and the first end cap 1. As shown in the figure, in the initial state of high-pressure driving and injection waiting, the second end cover 14 is fixedly connected to the cylinder 8 in the same way at the other end of the cylinder 8 to form a sealing structure, the injection mechanism is partially arranged in the space defined by the cylinder 8, the first end cover 1 and the second end cover 14, space conditions are provided for an external high-pressure driving assembly to drive the injection mechanism, the injection mechanism comprises a piston 9 and a firing pin 13, the piston 9 is nested in the cylinder 8 and can reciprocate under the pressure driving, and the firing pin 13 is nested in the piston 9 and can be driven by the piston 9 to stroke.
In some embodiments, the high-pressure driving assembly may be an externally provided hydraulic power source or a pneumatic power source, and can be set according to actual conditions as long as the piston 9 can be provided with power for stroke movement; preferably, the high-pressure driving assembly in this embodiment includes a high-pressure air source 6 and a reversing valve 5, specifically, the high-pressure air source 6 is a portable high-pressure air bottle, nitrogen is filled in the bottle, a throttle valve 7 is disposed between the high-pressure air source 6 and the reversing valve 5, the high-pressure air source 6 controls the reciprocating stroke motion of a piston 9 through the throttle valve 7 and the reversing valve 5, the throttle valve 7 is used for controlling the flow rate of the air source, in this embodiment, the reversing valve 5 is a two-position four-way reversing valve, and the reversing valve 5 is used for changing the air intake and exhaust directions of the air source so as to change the moving direction of the piston. Therefore, the high-pressure nitrogen is used as a power source of the high-pressure driving assembly, the cost is low, the environment is protected, the throttle valve 7 is arranged between the high-pressure air source 6 and the reversing valve 5, the pressure can be conveniently regulated, the throttling and the pressure reduction are realized, and the reliability of the injection loading process is enhanced.
In some embodiments, a first sealing ring 11 and a third sealing ring 24 are disposed between the cylinder 8 and the piston 9, specifically, the third sealing ring 24 is disposed at a position close to the first end cap 1, the first sealing ring 11 is disposed at another end position of the piston 9 far from the first end cap 1, that is, the piston 9 and the cylinder 8 are both composed of cylinders with different diameters, and when the piston 9 moves inside the cylinder 8, different closed spaces are generated between the piston 9 and the cylinder 8; the fourth sealing ring 27 is arranged between the first end cover 1 and the cylinder body 8, so that energy loss caused by pressure leakage inside the cylinder body 8 is prevented, a first cavity 26 is formed between the piston 9 and the first end cover 1 through the third sealing ring 24 and the fourth sealing ring 27 inside the cylinder body 8, a second cavity 23 is formed between the cylinder body 8 and the piston 9 through the first sealing ring 11 and the third sealing ring 24 in a sealing mode, and the first cavity 26 and the second cavity 23 can provide space for input driving pressure of the high-pressure driving assembly.
Specifically, the first sealing ring, the second sealing ring, the third sealing ring and the fourth sealing ring are all O-shaped sealing rings so as to facilitate installation.
In some embodiments, the second end cap 14 includes a cap body 141 and a through column 142 penetrating the center of the cap body 141, the through column 142 is provided with a through hole 1421 at the center, as shown in fig. 9, which is a schematic structural view of the second end cap 14 in this embodiment, the second end cap 14 is provided with a counter bore for being fixedly connected to the cylinder 8 by a bolt, a communication hole 1411 is provided on a side surface of the second end cap 14, the through column 142 is provided coaxially and integrally with the second end cap 14 on two sides of the second end cap 14, a first long through column 1422 is provided on one side of the second end cap 14, a second short through column 1423 is provided on the other side, and an external thread is provided on the second through column 1423.
It can be understood that the second end cap 14 is connected to the cylinder 8 by a hexagon socket head cap screw, and at this time, the first through cylinder 1422 at the longer end of the through cylinder 142 extends into the cylinder 8, and the second through cylinder 1423 at the other end is exposed outside the cylinder 8, and the striker 13 can reciprocate in the through hole 1421; a second sealing ring 21 is arranged between the striker 13 and the through column 142, when the striker 13 moves in the through hole (1421), a liquid suction cavity 16 is formed between the right end of the striker 13 and the through column 142, the liquid suction cavity 16 is used for absorbing and storing external liquid medicine, and the volume of the liquid suction cavity 16 directly influences the injection flow and the injection duration of the nozzle 15; a third cavity 22 is formed among the piston 9, the striker 13 and the through column 142, the third cavity 22 provides a space for the piston 9 to drive the striker 13 to move, a pressure relief hole 4 is formed in the piston 9, the third cavity 22 is communicated with the second cavity 23 through the pressure relief hole 4, the piston 9 and the striker 13 provide an injection force under high pressure impact, the third cavity 22 is communicated with the second cavity 23 through the pressure relief hole 4 to ensure that high-pressure gas in the third cavity 22 is discharged in time in the forward movement process after the striker 13 is impacted by the piston 9, the high-pressure gas generated in the third cavity 22 can be discharged into the second cavity 23 to keep balance of internal and external pressure, the service life of the device is prolonged, and the device is prevented from being damaged due to overlarge internal pressure of the third cavity 22.
In some embodiments, a sealing plug 25 is disposed at one end of the piston 9 coaxially with the firing pin 13, a stroke gap is formed between the sealing plug 25 and the firing pin 13, and one end of the firing pin 13 is limited in the stroke gap to ensure that the firing pin 13 can be moved by the piston 9 to perform the impact injection. Specifically, the sealing plug 25 is a hexagon socket plug with a sealing ring inside, and the depth of the sealing plug 25 screwed into a stroke gap can be adjusted, so that the initial kinetic energy of the piston 9 when impacting the striker 13 is changed, and through the arrangement of the sealing plug 25, on one hand, the first cavity 26 and the third cavity 22 are separated, and pressure relief is avoided; on the other hand, a stroke gap is formed between the sealing plug 25 and the firing pin 13, when the high-pressure gas drives the piston 9 to move rightwards through the first cavity 26, the sealing plug 25 is contacted with the firing pin 13 after a section of high-speed stroke and then moves rightwards at a high speed along the axis together, the time required by the liquid medicine to reach the peak speed can be reduced, and the capability of jet penetrating through skin soft tissues is improved.
In some embodiments, at least one guide ring is provided between the piston 9 and the cylinder 8, and at least one guide ring is provided between the striker 13 and the through-post 142. Specifically, a first guide ring 3 is arranged between the piston 9 and the cylinder 8 and at one end close to the third sealing ring 24, a second guide ring 12 is arranged between the piston 9 and the cylinder 8 and at one end close to the first sealing ring 11, and the first guide ring 3 and the second guide ring 12 play a role in supporting and guiding the piston 9, so that the piston 9 can be prevented from directly contacting and rubbing the cylinder 8 in the movement process, and the service life of the device is prolonged; a third guide ring 19 and a fourth guide ring 20 are arranged between the striker 13 and the through column 142 and near the second sealing ring 21, and the third guide ring 19 and the fourth guide ring 20 support and guide the through column 142, so that the striker 13 can be prevented from directly contacting and rubbing the through column 142 when moving in the through hole 1421, and the service life of the device can be prolonged. Guide rings are arranged between the piston 9 and the cylinder 8 and between the firing pin 13 and the through column 142, which can correct the coaxiality between the cylinder 8 and the piston 9 and between the firing pin 13 and the second end cover 14, so that the situation that the piston 9 and the cylinder 8 and between the through column 142 and the firing pin 13 are eccentric mutually to influence the sealing and injection effects of the system under the condition of high-pressure driving of the device is avoided, and therefore, the arrangement of the guide rings can improve the axial impact precision of the device and prolong the service life of the device.
In some embodiments, the cylinder 8 is provided with a first connecting channel 2 and a second connecting channel 10, and the air holes of the first connecting channel 2 and the second connecting channel 10 are provided with internal threads, so that the cylinder can be connected with an air pipe through a connector. The one end trachea of high pressure drive assembly passes through first linkage 2 and first cavity 26 intercommunication, and other end trachea passes through second linkage 10 and second cavity 23 intercommunication, through set up a plurality of linkage on cylinder body 8 for outside high pressurized air source 6 can enter into the first cavity 26 and the second cavity 23 inside of device, thereby realizes controlling piston 9 and firing pin 13 through high-pressure gas and carries out quick reciprocating stroke motion.
In some embodiments, the injection mechanism further comprises a nozzle 15, the nozzle 15 is detachably connected to the outer side of the second end cap 14, and the liquid medicine in the liquid suction cavity 16 is communicated with the outside for injection through the arrangement of the nozzle 15; in other embodiments, the aperture of the nozzle 15 can be set according to practical requirements, and is not limited to the size of the present invention. The nozzle 15 improves the efficiency and practicality of injection by providing multiple sizes to vary the jet impact velocity.
In some embodiments, the injection mechanism further includes a liquid storage container 18, the second end cap 14 has a communication hole 1411, the liquid storage container 18 communicates with the liquid suction chamber 16 through the communication hole 1411, and a one-way valve 17 is disposed in the communication hole 1411 to limit one-way delivery of the liquid medicine in the liquid storage container 18 to the liquid suction chamber 16 through the communication hole 1411. This embodiment provides the storage liquid medicine for injection mechanism through setting up liquid storage container 18, leads to liquid storage container 18 and imbibition chamber 16 through intercommunicating pore 1411, restricts the liquid medicine flow direction through set up the check valve in intercommunicating pore 1411, and the check valve 17 only allows the liquid medicine to flow to imbibition chamber 16 from liquid storage container 18 promptly, has effectively avoided the circumstances of liquid medicine refluence to take place in the injection process, influences the injection effect.
The working process of one embodiment is detailed in fig. 2, fig. 3 and fig. 4, and specifically as follows:
firstly, fig. 2 is a schematic structural diagram of an initial state, and it can be seen from fig. 2 that, in the initial state, the piston 9 is in a state of being close to the first end cap 1, at this time, the first cavity 26 is compressed, the liquid suction cavity is already loaded with a certain amount of liquid medicine, the throttle valve 7 is opened, gas in the high-pressure gas source 6 enters the first cavity 26 through the first connecting pipeline 2 via the throttle valve 7 and the left position of the reversing valve 5, the piston 9 moves axially rightward under the pushing of the high-pressure gas in the first cavity 26, gas in the third cavity 22 is discharged into the second cavity 23 through the pressure relief hole 4 to maintain the pressure balance inside and outside the device, in this process, the high-pressure gas enters the first cavity 26, the low-pressure gas is discharged from the second cavity 23, and the first cavity 26 and the second cavity 23 can alternately enter and discharge. Next, as shown in fig. 3, which is a structural schematic diagram of the critical injection state, after the sealing plug 25 contacts the striker 13 through the stroke gap in the piston 9, the two components move together along the axial direction at a high speed, at which time the check valve 17 is in a reverse blocking state, the liquid medicine in the liquid suction chamber 16 is ejected through the nozzle 15 arranged outside the second end cap 14 under the high-speed impact of the striker 13, the ejected liquid medicine has an extremely high impact speed and a small jet diameter, the positions of the components at the end of the impact injection process are shown in fig. 4, and at this time, the liquid medicine in the liquid suction chamber 16 is completely injected to the outside.
After the injection is completed, the piston 9 and the striker 13 are both located within the cylinder 8 axially adjacent to the inner end face of the second end cap 14, as shown in fig. 4. The reversing valve 5 is adjusted to the right, at this time, high-pressure gas enters the second cavity 23 through the second connecting pipeline 10, the gas pushes the piston 9 and the sealing plug 25 to move back to the initial position close to the first end cover 1, the striker 13 is also driven by the piston 9 to return to the initial position, during the process, the liquid suction cavity 16 generates huge negative pressure, the check valve 17 is in a one-way conduction state, liquid medicine in the liquid storage container 18 enters the liquid suction cavity 16 through the check valve 17 under huge pressure difference, and the perforation 152 of the nozzle 15 has a small aperture, so that the flow of the gas sucked by the nozzle is negligible. The entire device is reset following the inhalation of the medical fluid, at which time the relative positions of the various components of the device return to the initial state shown in fig. 2.
Example 1
In the embodiment, the high-pressure driving needle-free injection device is used for delivering external liquid medicine to an intradermal space of an individual and comprises a cylinder body 8, an injection mechanism and a high-pressure driving assembly arranged outside the cylinder body 8, wherein the left end of the cylinder body 8 is connected with a first end cover 1, and the right end of the cylinder body 8 is connected with a second end cover 14; the injection mechanism is partially arranged in a space defined by the cylinder 8, the first end cover 1 and the second end cover 14 and comprises a piston 9 and a firing pin 13, wherein the firing pin 13 is nested in the piston 9, and the piston 9 is nested in the cylinder 8; the high-pressure driving component comprises a high-pressure air source 6 and a reversing valve 5, and a throttle valve 7 is arranged between the high-pressure air source 6 and the reversing valve 5; the high pressure drive assembly communicates to the interior of the cylinder 8 and provides the drive force for the injection mechanism. The injection mechanism further comprises a liquid storage container 18, a communication hole 1411 is formed in the second end cover 14, the liquid storage container 18 is used for conveying external liquid medicine to the communication hole 1411, the communication hole 1411 is connected to the liquid suction cavity 16, and a one-way valve 17 is arranged between the liquid storage container 18 and the liquid suction cavity 16. A first seal ring 11 and a third seal ring 24 are provided between the cylinder 8 and the piston 9, a fourth seal ring 27 is provided between the first end cap 1 and the cylinder 8, a first cavity 26 is formed between the piston 9 and the first end cap 1 by the third seal ring 24 and the fourth seal ring 27 inside the cylinder 8, and a second cavity 23 is formed between the cylinder 8 and the piston 9 by the first seal ring 11 and the third seal ring 24. The cylinder 8 is provided with a first connecting channel 2 and a second connecting channel 10, one end of the high-pressure driving assembly is communicated with the first cavity 26 through the first connecting channel 2, the other end of the high-pressure driving assembly is communicated with the second cavity 23 through the second connecting channel 10, and the piston 9 is controlled to drive the striker 13 to perform reciprocating stroke motion in the through column 142 by controlling the pressure in the first cavity 26 and the pressure in the second cavity 23. The second end cap 14 includes a cap body 141 and a through column 142 penetrating the center of the cap body 141, a through hole 1421 is provided in the center of the through column 142, and the striker 13 can reciprocate in the through hole 1421; a second sealing ring 21 is arranged between the striker 13 and the through column 142, when the striker 13 moves in the through hole 1421, a liquid suction cavity 16 is formed between the right end of the striker 13 and the through column 142, and the liquid suction cavity 16 is used for absorbing and containing external liquid medicine; a third cavity 22 is formed among the piston 9, the striker 13 and the through column 142, and a pressure relief hole 4 is formed in the piston 9, and the third cavity 22 is communicated with the second cavity 23 through the pressure relief hole 4. A sealing plug 25 is provided at one end of the piston 9 coaxially with the striker 13, and a stroke gap is formed between the sealing plug 25 and the striker 13. At least one guide ring is provided between the piston 9 and the cylinder 8, and at least one guide ring is provided between the striker 13 and the through-post 142. The injection mechanism further comprises a nozzle 15, the nozzle 15 is detachably connected to the outer side of the second end cover 14, the aperture of the nozzle 15 is 0.5mm, 0.3mm or 0.1mm, and the nozzle can be correspondingly sized according to requirements in other embodiments.
As shown in fig. 9, which is a schematic perspective view of the second end cap 14 in embodiment 1, it can be seen from the drawing that through pillars 142 penetrating through the cap body 141 are disposed on two side surfaces of the center of the cap body 141 of the second end cap 14, through holes 1421 are disposed in the through pillars 142, specifically, a first long through pillar 1422 is disposed on one side of the cap body 141, a second short through pillar 1423 is disposed on the opposite other side, and the through holes 1421 are disposed in the first through pillar 1422 and the second through pillar 1423 in a penetrating manner.
The structure of the nozzle 15 in this embodiment is a straight and conical injection nozzle 15, as shown in fig. 5, which is a schematic sectional view of a three-dimensional structure of the straight and conical injection nozzle 15; in this embodiment, the straight cone type injection nozzle 15 includes a cylindrical body having a non-through connection hole 154 formed at one end and a frustum 151 formed at the other end, and a hollow cone 153 and a perforation hole 152 coaxially formed at a non-through portion of the body in this order.
The straight cone type injection nozzle 15 is screwed with a second through cylinder 1423 extending out of the second end cover 14 through a connecting hole 154, specifically, the straight cone type injection nozzle 15 has internal threads, the second through cylinder 1423 has external threads, and the fixing is realized by screwing the internal threads and the external threads; so that the through hole 1421, the hollow cone 153 and the perforation 152 are in coaxial communication to secure the nozzle 15 to the device for injection. The straight cone injection nozzle 15 is connected to the second through cylinder 1423 which is short outside the second end cap 14 by screwing, so that the disassembly operation is relatively convenient, and the liquid medicine is only injected to the outside from the perforation 152. The structure of the straight cone type injection nozzle 15 influences the jet flow shape, the hollow cone 153 structure with the contraction angle of 30 degrees is adopted in the straight cone type injection nozzle, the design can reduce the energy loss to the maximum extent, the jet flow controllability of the straight cone type injection nozzle 15 is better, the energy utilization rate is higher,
example 2
The high-pressure-driven needleless injection device provided in this embodiment is substantially the same as the high-pressure-driven needleless injection device provided in embodiment 1, only the differences therebetween are described herein, and the descriptions of the parts of this embodiment that are the same as those of embodiment 1 are omitted.
This example differs from example 1 in that: the nozzle 15 has a different structure, the second cover 14 has a different structure, and the striker 13 has a different length.
The nozzle 15 in this embodiment is a flat-top injection nozzle 15, which is a schematic sectional view of a three-dimensional structure of the flat-top injection nozzle 15 as shown in fig. 6; the flat-top injection nozzle 15 is a body with a disc-shaped structure, a connecting column 156 is arranged at the center of one side surface of the body, a liquid channel 157 which penetrates through the center of the connecting column and the center of the flat-top injection nozzle 15 is arranged in the connecting column 156, a frustum 151 is coaxially arranged with the disc-shaped body on the other side surface of the body, a perforation 152 is arranged in the frustum 151, the perforation 152 is communicated with the liquid channel 157, and a plurality of bolt holes 155 are uniformly distributed on the flat-top injection nozzle 15.
The outer side of the second end cap 14 is a plane, that is, the difference from embodiment 1 is that embodiment 2 does not have the second through-cylinder 1423 and does not connect the nozzle in a threaded manner, as shown in fig. 10, which is a schematic structural diagram of the second end cap 14 in embodiment 2, the through-column 142 is disposed on one side of the cap body 141, and the through-hole 1421 is disposed in the through-column 142.
The specific embodiment is that the connection column 156 of the flat-top injection nozzle 15 is inserted into the through hole 1421, so that the liquid channel 157 is coaxially communicated with the through hole 1421, the left side surface of the flat-top injection nozzle 15 is attached to the outer side surface of the second end cap 14, the cap body 141 is provided with bolt holes matched with the bolt holes 155 on the flat-top injection nozzle 15, and a plurality of hexagon socket head cap bolts are inserted into the bolt holes 155 to lock the flat-top injection nozzle 15 and the second end cap 14, so that the nozzle 15 is fixed on the second end cap 14. Preferably, a fifth sealing ring 29 is disposed between the connecting column 156 and the second end cap 14, and the fifth sealing ring is preferably an O-ring for easy installation, so as to prevent the liquid medicine in the liquid suction chamber 16 from leaking outwards, and ensure that the liquid medicine is injected to the outside only from the liquid passage 157 and the perforation 152.
As can be seen from fig. 2 and fig. 7 and the above description, the left structure of the whole device of the embodiment 1 and the embodiment 2 is the same, and since the specific structure of the nozzle 15 and the second end cap 14 in the embodiment 1 is different from that of the embodiment 2, the through pillar 142 is arranged on both sides of the second end cap 14 in the embodiment 1, the length of the right nozzle 15 in the embodiment 1 is larger than that of the right nozzle 15 in the embodiment 2, and the cylinder 8 and the piston 9 of the two embodiment devices are generally the same size, so as to avoid interference, the length of the striker 13 in the embodiment 2 should be smaller than that of the striker 13 in the embodiment 1.
The technical effect same as that of the embodiment 1 can be achieved by the arrangement of the embodiment 2, and the flat-top injection nozzle 15 is simple to process and is locked on the second end cover 14 through the bolt, so that the problem that the nozzle 15 in the embodiment 1 cannot be used due to thread failure caused by threaded connection is avoided. Meanwhile, a fifth sealing ring 29 for static sealing is arranged between the flat-top injection nozzle 15 and the second end cover 14, so that the sealing performance of the connection between the flat-top injection nozzle and the second end cover through bolts can be ensured.
Fig. 7 and 8 are schematic structural views of the high-pressure driven needleless injection device of embodiment 2 in an initial injection state and a completed injection state, respectively, and the structures are the same except for the specific structure of the nozzle 15, the length of the striker 13, and the connection manner of the nozzle 15 and the second endcap 14, which are not repeated herein.
It should be understood that the terms of orientation of up, down, left, right, front, back, top, bottom, etc., referred to or may be referred to in this specification, are defined relative to the configuration shown in the drawings, and are relative terms, and thus may be changed accordingly depending on the position and the use state of the device. Therefore, these and other directional terms should not be construed as limiting terms.
While the foregoing is directed to the preferred embodiment of the present application, and not to the limiting thereof in any way and any way, it will be understood by those skilled in the art that various changes and modifications may be made without departing from the spirit and scope of the invention as defined by the appended claims. Those skilled in the art can make various changes, modifications and equivalent arrangements to those skilled in the art without departing from the spirit and scope of the present application; moreover, any equivalent alterations, modifications and variations of the above-described embodiments according to the spirit and techniques of this application are intended to be within the scope of the claims of this application.
Claims (10)
1. A high pressure driven, needle free injection device for delivering an external medical fluid to an intradermal space in an individual comprising:
the cylinder body (8), one end of the cylinder body (8) is connected with a first end cover (1), and the other end of the cylinder body (8) is connected with a second end cover (14);
an injection mechanism partially arranged in a space enclosed by the cylinder (8), the first end cover (1) and the second end cover (14), and comprising a piston (9) and a firing pin (13), wherein the firing pin (13) is nested in the piston (9), and the piston (9) is nested in the cylinder (8);
and a high-pressure driving assembly mounted outside the cylinder body (8), the high-pressure driving assembly being communicated to the inside of the cylinder body (8) and providing a driving force for the injection mechanism.
2. The high-pressure-driven needle-free injection device according to claim 1, wherein a first seal ring (11) and a third seal ring (24) are arranged between the cylinder (8) and the piston (9), a fourth seal ring (27) is arranged between the first end cap (1) and the cylinder (8), a first cavity (26) is formed between the piston (9) and the first end cap (1) by the third seal ring (24) and the fourth seal ring (27) inside the cylinder (8), and a second cavity (23) is formed between the cylinder (8) and the piston (9) by the first seal ring (11) and the third seal ring (24).
3. The high-pressure driving needle-free injection device according to claim 2, wherein the second end cap (14) comprises a cap body (141) and a through column (142) arranged at the center of the cap body (141), the through column (142) is provided with a through hole (1421) at the center, and the striker (13) can be inserted into the through hole (1421) for reciprocating motion; a second sealing ring (21) is arranged between the firing pin (13) and the through column (142), when one end of the firing pin (13) moves in the through hole (1421), a liquid suction cavity (16) is formed between the other end of the firing pin (13) and the through column (142), and the liquid suction cavity (16) is used for absorbing and containing external liquid medicine; a third cavity (22) is formed among the piston (9), the striker (13) and the through column (142), a pressure relief hole (4) is formed in the piston (9), and the third cavity (22) is communicated with the second cavity (23) through the pressure relief hole (4).
4. The high pressure driven needle-free injection device according to claim 3, wherein a sealing plug (25) is provided at one end of the piston (9) coaxially with the firing pin (13), and a stroke gap is formed between the sealing plug (25) and the firing pin (13).
5. The high pressure driven needle-free injection device according to claim 3, wherein at least one guide ring is provided between the piston (9) and the cylinder (8) and between the firing pin (13) and the through post (142).
6. The high pressure driven needle-free injection device according to any one of claims 1 to 5, wherein a first connecting channel (2) and a second connecting channel (10) are provided on the cylinder (8), one end of the high pressure driving assembly is communicated with the first cavity (26) through the first connecting channel (2), the other end is communicated with the second cavity (23) through the second connecting channel (10), and the pressure in the first cavity (26) and the second cavity (23) is controlled, so that the piston (9) is controlled to drive the striker (13) to perform reciprocating stroke motion in the through column (142).
7. The high pressure driven needle-free injection device according to any of claims 1 to 5, wherein the injection mechanism further comprises a nozzle (15), the nozzle (15) being detachably attached to the outside of the second end cap (14).
8. The high pressure driven needle-free injection device according to claim 7, wherein the nozzle (15) is flat-top or conical-straight in shape.
9. The high-pressure driving needle-free injection device according to claim 1, wherein the injection mechanism further comprises a liquid storage container (18), a communication hole (1411) is formed in the second end cap (14), the liquid storage container (18) is communicated with the liquid suction cavity (16) through the communication hole (1411), and a one-way valve (17) is arranged in the communication hole (1411) to limit unidirectional transmission of liquid medicine in the liquid storage container (18) to the liquid suction cavity (16) through the communication hole (1411).
10. The high pressure driven needle-free injection device according to claim 1, wherein the high pressure drive assembly comprises a high pressure gas source (6) and a reversing valve (5), a throttle valve (7) being provided between the high pressure gas source (6) and the reversing valve (5).
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CN118178786A (en) * | 2024-04-01 | 2024-06-14 | 上海稷实医疗科技有限公司 | Injection syringe |
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