CN114981272A - 吡咯并嘧啶化合物的治疗噬血细胞综合征的用途 - Google Patents
吡咯并嘧啶化合物的治疗噬血细胞综合征的用途 Download PDFInfo
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Abstract
吡咯并嘧啶化合物治疗噬血细胞综合征的用途，具体涉及式(I)化合物、其立体异构体、或其药学上可接受的盐及其药物组合物治疗噬血细胞综合征的用途。
Description
PCT国内申请，说明书已公开。
Claims (15)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010157375 | 2020-03-09 | ||
| CN2020101573754 | 2020-03-09 | ||
| PCT/CN2021/079820 WO2021180093A1 (zh) | 2020-03-09 | 2021-03-09 | 吡咯并嘧啶化合物的治疗噬血细胞综合征的用途 |
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| Publication Number | Publication Date |
|---|---|
| CN114981272A true CN114981272A (zh) | 2022-08-30 |
Family
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| CN202180008532.8A Pending CN114981272A (zh) | 2020-03-09 | 2021-03-09 | 吡咯并嘧啶化合物的治疗噬血细胞综合征的用途 |
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| Country | Link |
|---|---|
| US (1) | US20230133735A1 (zh) |
| EP (1) | EP4119562A4 (zh) |
| CN (1) | CN114981272A (zh) |
| WO (1) | WO2021180093A1 (zh) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2022296552A1 (en) * | 2021-06-21 | 2024-01-04 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Use of pyrrolopyrimidine compound and pharmaceutical composition thereof for treating chronic graft versus host disease |
| WO2023179547A1 (zh) * | 2022-03-21 | 2023-09-28 | 正大天晴药业集团股份有限公司 | 吡咯并嘧啶化合物治疗中高危骨髓纤维化的用途 |
| WO2024027790A1 (zh) * | 2022-08-04 | 2024-02-08 | 正大天晴药业集团股份有限公司 | 吡咯并嘧啶化合物治疗急性移植物抗宿主病的用途 |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017101777A1 (zh) * | 2015-12-15 | 2017-06-22 | 北京赛林泰医药技术有限公司 | 吡咯并嘧啶化合物的盐 |
| WO2017114461A1 (zh) * | 2015-12-31 | 2017-07-06 | 正大天晴药业集团股份有限公司 | 一种芦可替尼的合成工艺 |
| WO2017215627A1 (zh) * | 2016-06-16 | 2017-12-21 | 正大天晴药业集团股份有限公司 | 手性吡咯并嘧啶化合物的制备方法 |
| WO2017215628A1 (zh) * | 2016-06-16 | 2017-12-21 | 北京赛林泰医药技术有限公司 | 含有取代环戊基的吡咯并嘧啶化合物 |
| WO2017215630A1 (zh) * | 2016-06-16 | 2017-12-21 | 正大天晴药业集团股份有限公司 | 作为jak抑制剂的吡咯并嘧啶化合物的结晶 |
| CN107001378B (zh) * | 2014-12-16 | 2019-08-16 | 正大天晴药业集团股份有限公司 | 吡咯并嘧啶化合物 |
-
2021
- 2021-03-09 CN CN202180008532.8A patent/CN114981272A/zh active Pending
- 2021-03-09 EP EP21767840.8A patent/EP4119562A4/en active Pending
- 2021-03-09 WO PCT/CN2021/079820 patent/WO2021180093A1/zh unknown
- 2021-03-09 US US17/910,331 patent/US20230133735A1/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107001378B (zh) * | 2014-12-16 | 2019-08-16 | 正大天晴药业集团股份有限公司 | 吡咯并嘧啶化合物 |
| WO2017101777A1 (zh) * | 2015-12-15 | 2017-06-22 | 北京赛林泰医药技术有限公司 | 吡咯并嘧啶化合物的盐 |
| WO2017114461A1 (zh) * | 2015-12-31 | 2017-07-06 | 正大天晴药业集团股份有限公司 | 一种芦可替尼的合成工艺 |
| WO2017215627A1 (zh) * | 2016-06-16 | 2017-12-21 | 正大天晴药业集团股份有限公司 | 手性吡咯并嘧啶化合物的制备方法 |
| WO2017215628A1 (zh) * | 2016-06-16 | 2017-12-21 | 北京赛林泰医药技术有限公司 | 含有取代环戊基的吡咯并嘧啶化合物 |
| WO2017215630A1 (zh) * | 2016-06-16 | 2017-12-21 | 正大天晴药业集团股份有限公司 | 作为jak抑制剂的吡咯并嘧啶化合物的结晶 |
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| Title |
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| 王晶石，等: "芦可替尼挽救治疗难治/复发噬血细胞综合征三例并文献复习", 《中华血液学杂志》, vol. 40, no. 1, pages 73 - 75 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2021180093A1 (zh) | 2021-09-16 |
| US20230133735A1 (en) | 2023-05-04 |
| EP4119562A1 (en) | 2023-01-18 |
| EP4119562A4 (en) | 2024-04-24 |
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