CN114903171A - Hyaluronic acid beautifying bird's nest and preparation method thereof - Google Patents
Hyaluronic acid beautifying bird's nest and preparation method thereof Download PDFInfo
- Publication number
- CN114903171A CN114903171A CN202210570015.6A CN202210570015A CN114903171A CN 114903171 A CN114903171 A CN 114903171A CN 202210570015 A CN202210570015 A CN 202210570015A CN 114903171 A CN114903171 A CN 114903171A
- Authority
- CN
- China
- Prior art keywords
- cubilose
- hyaluronic acid
- preparation
- nest
- bird
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title claims abstract description 68
- 229920002674 hyaluronan Polymers 0.000 title claims abstract description 67
- 229960003160 hyaluronic acid Drugs 0.000 title claims abstract description 67
- 238000002360 preparation method Methods 0.000 title claims abstract description 26
- 244000000626 Daucus carota Species 0.000 title claims abstract description 18
- 235000005770 birds nest Nutrition 0.000 title claims abstract description 18
- 235000005765 wild carrot Nutrition 0.000 title claims abstract description 18
- 239000007788 liquid Substances 0.000 claims abstract description 46
- 230000001815 facial effect Effects 0.000 claims abstract description 22
- 239000000203 mixture Substances 0.000 claims abstract description 9
- 238000000265 homogenisation Methods 0.000 claims description 46
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 39
- 238000001291 vacuum drying Methods 0.000 claims description 33
- 238000002791 soaking Methods 0.000 claims description 13
- 238000007493 shaping process Methods 0.000 claims description 11
- 238000009210 therapy by ultrasound Methods 0.000 claims description 11
- 238000005303 weighing Methods 0.000 claims description 10
- 230000003796 beauty Effects 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 4
- 238000007654 immersion Methods 0.000 claims description 2
- 235000021487 ready-to-eat food Nutrition 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 13
- 235000013305 food Nutrition 0.000 abstract description 7
- 239000002994 raw material Substances 0.000 abstract description 6
- 230000003712 anti-aging effect Effects 0.000 abstract description 2
- 238000012545 processing Methods 0.000 abstract description 2
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 abstract 1
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 abstract 1
- 239000012141 concentrate Substances 0.000 abstract 1
- 238000007670 refining Methods 0.000 abstract 1
- 229940116269 uric acid Drugs 0.000 abstract 1
- 238000012795 verification Methods 0.000 abstract 1
- 230000000052 comparative effect Effects 0.000 description 11
- 241000699670 Mus sp. Species 0.000 description 10
- 210000002784 stomach Anatomy 0.000 description 4
- 241001465754 Metazoa Species 0.000 description 3
- 229920002385 Sodium hyaluronate Polymers 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 230000032683 aging Effects 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000002262 irrigation Effects 0.000 description 2
- 238000003973 irrigation Methods 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 210000002381 plasma Anatomy 0.000 description 2
- 229940010747 sodium hyaluronate Drugs 0.000 description 2
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 230000037303 wrinkles Effects 0.000 description 2
- 235000020927 12-h fasting Nutrition 0.000 description 1
- 102000018386 EGF Family of Proteins Human genes 0.000 description 1
- 108010066486 EGF Family of Proteins Proteins 0.000 description 1
- 229920002683 Glycosaminoglycan Polymers 0.000 description 1
- 241000699666 Mus <mouse, genus> Species 0.000 description 1
- 244000046052 Phaseolus vulgaris Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 210000004381 amniotic fluid Anatomy 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 210000001188 articular cartilage Anatomy 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 210000005252 bulbus oculi Anatomy 0.000 description 1
- 244000309464 bull Species 0.000 description 1
- 230000010261 cell growth Effects 0.000 description 1
- 239000007910 chewable tablet Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 210000000695 crystalline len Anatomy 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000002360 explosive Substances 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 210000001508 eye Anatomy 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- ZFGMDIBRIDKWMY-PASTXAENSA-N heparin Chemical compound CC(O)=N[C@@H]1[C@@H](O)[C@H](O)[C@@H](COS(O)(=O)=O)O[C@@H]1O[C@@H]1[C@@H](C(O)=O)O[C@@H](O[C@H]2[C@@H]([C@@H](OS(O)(=O)=O)[C@@H](O[C@@H]3[C@@H](OC(O)[C@H](OS(O)(=O)=O)[C@H]3O)C(O)=O)O[C@@H]2O)CS(O)(=O)=O)[C@H](O)[C@H]1O ZFGMDIBRIDKWMY-PASTXAENSA-N 0.000 description 1
- 229960001008 heparin sodium Drugs 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 230000002297 mitogenic effect Effects 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 210000002826 placenta Anatomy 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 230000002040 relaxant effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 210000003491 skin Anatomy 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 235000013547 stew Nutrition 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
- A23L5/30—Physical treatment, e.g. electrical or magnetic means, wave energy or irradiation
- A23L5/32—Physical treatment, e.g. electrical or magnetic means, wave energy or irradiation using phonon wave energy, e.g. sound or ultrasonic waves
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The invention discloses a preparation method of hyaluronic acid beautifying bird's nest, relating to the technical field of food processing, and the preparation method is characterized by comprising the following steps: s1, preparing cubilose liquid; s2, homogenizing by microjet at high pressure; s3, concentrating; and S4, forming. The bird's nest is not directly mixed with other raw materials in this application, but make it into bird's nest liquid and mix with food level hyaluronic acid again, under the effect of microfluidization high pressure homogeneity, several kinds of raw materials fully contact, obtain the refining, the homogeneous product, then concentrate, fix the line, fine taste and the impression that has kept being equivalent with traditional bird's nest, and it is convenient to eat, and be digested and absorbed easily, the beautiful bird's nest of please uric acid facial makeup that obtains is crease-resistant, anti-aging, facial makeup is effectual, it all shows comparatively apparent facial makeup effect in male and female mouse to discover through experimental verification.
Description
Technical Field
The invention belongs to the technical field of food processing, and particularly relates to hyaluronic acid beautifying bird's nest and a preparation method thereof.
Background
The impression of the beauty and beauty efficacy of cubilose in the mind of consumers is well-rooted and there are always high-end labels. Researches show that the cubilose contains a large amount of bioactive proteins, amino acids, trace elements and the like, particularly epidermal growth factors and mitogenic components, and is easy to be absorbed by human bodies. The water solution of active glucoprotein can directly stimulate the cell growth of immune system, promote metabolism and enhance body function. The cubilose acid contained in the cubilose has important functions in the aspects of beautifying and anti-aging, so the cubilose acid is popular with female consumer groups. Over the past 5 years, the industry of instant edible bird's nest in china has grown rapidly.
Hyaluronic Acid (HA), a scientific name, is an acidic mucopolysaccharide widely present in human and animal tissues such as placenta, amniotic fluid, lens, skin, articular cartilage, and was first isolated from the vitreous of bull's eye by ophthalmologists. Hyaluronic acid is also known as sodium hyaluronate, or sodium hyaluronate, since it is generally present in the form of a sodium salt. Hyaluronic acid can absorb about 1000 times of water per se, and has high viscoelasticity, super-strong water retention, permeability and good biocompatibility, so that the hyaluronic acid is widely applied to a plurality of fields of cosmetics, medicine, food and the like. Currently, hyaluronic acid raw materials are mainly obtained by microbial fermentation and animal tissue extraction. At present, the national public manufacturers of hyaluronic acid raw materials develop related edible hyaluronic acid products in various ways such as cooperating with partners and building own product research and development teams, and the like, and the released products comprise hyaluronic acid series oral liquid, soft sweets, tabletting candies and the like, and various products such as hyaluronic acid white kidney bean slimming chewable tablets, hyaluronic acid beverages and the like, and have the effects of keeping healthy, slimming, sleeping and relaxing, protecting liver and nourishing stomach, whitening and resisting oxidation and the like.
The combination of the consumption of hyaluronic acid and the increasingly mature edible bird's nest must produce a comprehensive effect of 1 + 1 > 2, and form a cross-boundary explosive product integrating the beauty industry and food! So far, among the edible hyaluronic acid products already marketed, no completely new creative product of a cross-border comprehensive type such as hyaluronic acid beauty bird's nest is available. And the existing cubilose products have the problems of poor digestion and absorption effects, low utilization rate and poor beautifying effect.
Disclosure of Invention
The invention aims to solve the existing problems and provides a hyaluronic acid beautifying cubilose and a preparation method thereof.
The invention is realized by the following technical scheme:
the preparation method of the hyaluronic acid facial beautification cubilose comprises the following steps:
s1, preparation of the cubilose liquid:
s101, immersing cubilose in warm water, performing immersion treatment for 3-4 hours, and performing ultrasonic treatment while immersing;
s102, after soaking, placing the mixture in a micro-jet high-pressure homogenizer for high-pressure homogenization, and obtaining a homogenized product A for later use;
s103, stewing the homogenized product A obtained in the step S102 in a pot to obtain colloidal cubilose liquid for later use;
s2, microfluid high-pressure homogenization:
weighing 70-90 parts by weight of the cubilose liquid obtained in the step S1 and 2-4 parts by weight of food-grade hyaluronic acid, and placing the cubilose liquid and the food-grade hyaluronic acid together in a micro-jet high-pressure homogenizer for high-pressure homogenization treatment to obtain a homogenized product B for later use;
s3, concentration:
placing the homogeneous product B obtained in the step S3 in a vacuum drying oven, and performing vacuum drying and concentration treatment under a low-temperature condition to obtain a concentrated solution for later use;
s4, forming:
shaping the concentrated solution obtained in the step S3 by extruding, shredding and slicing to obtain filiform or sheet nidus Collocaliae, and vacuum drying at low temperature to obtain hyaluronic acid beautifying nidus Collocaliae.
Furthermore, the weight volume ratio of the cubilose and the warm water in the step S101 is 1g: 100-200 mL.
Further, the temperature in the warm water is controlled to be 70 to 80 ℃ during the soaking treatment in the step S101.
Further, the power of the ultrasonic wave is controlled to be 100-300W during the ultrasonic wave treatment in the step S101, and the frequency of the ultrasonic wave is controlled to be 20-30 kHz.
Further, the working pressure is controlled to be 80 to 90MPa during the high-pressure homogenization treatment in the step S102, and the time of the homogenization treatment is 5 to 9 min.
Further, the working pressure is controlled to be 100 to 120MPa during the high-pressure homogenization treatment in the step S2, and the time of the homogenization treatment is 12 to 18 min.
Further, the vacuum degree is controlled to be 2-3 Pa during vacuum drying and concentration in the step S3, the temperature is controlled to be 30-40 ℃, and the concentration is carried out until the water content is 8-10%.
Further, the vacuum degree is controlled to be 2-3 Pa and the temperature is controlled to be 20-26 ℃ during the low-temperature vacuum drying treatment in the step S4.
A hyaluronic acid facial beautification cubilose is an instant food.
Compared with the prior art, the invention has the following advantages:
1. this application is under ultrasonic auxiliary action, place the cubilose in the warm water and soak, make the cubilose fully absorb water, then through high-speed collision in high-pressure homogeneity intracavity, the degree of polymerization of macromolecule descends in the cubilose, the part is converted into the micromolecular compound, then stew and boil and form cubilose liquid, this application does not directly mix cubilose with other raw materials, but makes it and mixes with food level hyaluronic acid again, under the effect of little efflux high-pressure homogeneity, several kinds of raw materials fully contact, obtain the product that refines, the homogeneity.
2. The food-grade hyaluronic acid and the cubilose are subjected to homogeneous fusion, then are concentrated and fixed to form rows, well keep the taste and the impression equivalent to those of the traditional cubilose, are convenient to eat and are easy to digest and absorb.
3. The hyaluronic acid facial beautification cubilose has the advantages of wrinkle resistance, aging resistance and good facial beautification effect, and tests prove that the hyaluronic acid facial beautification cubilose shows a relatively remarkable facial beautification effect in male and female mice.
Detailed Description
For further explanation of the present invention, reference will now be made to the following specific examples.
Example 1:
the preparation method of the hyaluronic acid beautifying cubilose comprises the following steps:
s1, preparation of the cubilose liquid:
s101, immersing cubilose in warm water at 70 ℃ for 3 hours, wherein the weight-volume ratio of the cubilose to the warm water is 1g:100mL, performing ultrasonic treatment while immersing, and controlling the power of ultrasonic waves to be 100W and the frequency of the ultrasonic waves to be 20 kHz;
s102, after soaking, placing the soaked product in a micro-jet high-pressure homogenizer for high-pressure homogenization treatment, controlling the working pressure to be 80MPa, and after 5min of homogenization treatment, obtaining a homogenized product A for later use;
s103, stewing the homogenized product A obtained in the step S102 in a pot to obtain colloidal cubilose liquid for later use;
s2, microfluid high-pressure homogenization:
weighing 70 parts of cubilose liquid obtained in the step S1 and 2 parts of food-grade hyaluronic acid in corresponding parts by weight, putting the cubilose liquid and the food-grade hyaluronic acid together into a micro-jet high-pressure homogenizer for high-pressure homogenization treatment, controlling the working pressure to be 100MPa, and homogenizing for 12min to obtain a homogenized product B for later use;
s3, concentration:
placing the homogeneous product B obtained in the step S3 in a vacuum drying oven, and performing vacuum drying and concentration treatment at low temperature, controlling the vacuum degree to be 2Pa and the temperature to be 30 ℃, and concentrating until the water content is 8% to obtain a concentrated solution for later use;
s4, forming:
shaping the concentrated solution obtained in the step S3 by means of extruding, shredding and slicing to obtain filiform or sheet bird 'S nest, and vacuum drying at low temperature to obtain hyaluronic acid beauty bird' S nest, wherein the vacuum degree is controlled to be 2Pa, and the temperature is controlled to be 20 ℃.
Example 2:
the preparation method of the hyaluronic acid facial beautification cubilose comprises the following steps:
s1, preparing the cubilose liquid:
s101, immersing cubilose in warm water at 75 ℃, wherein the weight-volume ratio of the cubilose to the warm water is 1g:150mL, immersing for 3.5 hours, and performing ultrasonic treatment while immersing, wherein the power of ultrasonic is controlled to be 200W, and the frequency of the ultrasonic is controlled to be 25 kHz;
s102, after soaking, placing the soaked product in a micro-jet high-pressure homogenizer for high-pressure homogenization treatment, controlling the working pressure to be 85MPa, and carrying out homogenization treatment for 7min to obtain a homogenized product A for later use;
s103, stewing the homogenized product A obtained in the step S102 in a pot to obtain colloidal cubilose liquid for later use;
s2, micro-jet high-pressure homogenization:
weighing 80 parts by weight of cubilose liquid obtained in the step S1 and 3 parts by weight of food-grade hyaluronic acid, placing the cubilose liquid and the food-grade hyaluronic acid together in a microjet high-pressure homogenizer for high-pressure homogenization treatment, controlling the working pressure to be 110MPa, and obtaining a homogenized product B for later use after 15min of homogenization treatment;
s3, concentration:
placing the homogeneous product B obtained in the step S3 in a vacuum drying oven, and performing vacuum drying and concentration treatment at low temperature, wherein the vacuum degree is controlled to be 2.5Pa, the temperature is controlled to be 35 ℃, and the concentration is performed until the water content is 9%, so as to obtain a concentrated solution for later use;
s4, forming:
shaping the concentrated solution obtained in the step S3 by extruding, shredding and slicing to obtain filiform or sheet nidus Collocaliae, and vacuum drying at low temperature to obtain hyaluronic acid beautifying nidus Collocaliae with vacuum degree of 2.5Pa and temperature of 23 deg.C.
Example 3:
the preparation method of the hyaluronic acid facial beautification cubilose comprises the following steps:
s1, preparing the cubilose liquid:
s101, immersing cubilose in warm water at the temperature of 80 ℃, wherein the weight-volume ratio of the cubilose to the warm water is 1g:200mL, immersing for 4 hours, and performing ultrasonic treatment while immersing, wherein the power of ultrasonic is controlled to be 300W, and the frequency of the ultrasonic is controlled to be 30 kHz;
s102, after soaking, placing the soaked product in a micro-jet high-pressure homogenizer for high-pressure homogenization, controlling the working pressure to be 90MPa, and homogenizing for 9min to obtain a homogenized product A for later use;
s103, stewing the homogenized product A obtained in the step S102 in a pot to obtain colloidal cubilose liquid for later use;
s2, microfluid high-pressure homogenization:
weighing 90 parts of cubilose liquid obtained in the step S1 and 4 parts of food-grade hyaluronic acid in corresponding parts by weight, putting the cubilose liquid and the food-grade hyaluronic acid together into a micro-jet high-pressure homogenizer for high-pressure homogenization treatment, controlling the working pressure to be 120MPa, and homogenizing for 18min to obtain a homogenized product B for later use;
s3, concentration:
placing the homogeneous product B obtained in the step S3 in a vacuum drying oven, and performing vacuum drying and concentration treatment at low temperature, controlling the vacuum degree to be 3Pa and the temperature to be 40 ℃, and concentrating until the water content is 10% to obtain a concentrated solution for later use;
s4, forming:
shaping the concentrated solution obtained in the step S3 by extruding, shredding and slicing to obtain filiform or sheet nidus Collocaliae, and vacuum drying at low temperature to obtain hyaluronic acid beautifying nidus Collocaliae with vacuum degree of 3Pa and temperature of 26 deg.C.
Comparative example 1:
the preparation method of the hyaluronic acid facial beautification cubilose comprises the following steps:
s1, preparing the cubilose liquid:
s101, immersing cubilose in warm water at 75 ℃, wherein the weight-volume ratio of the cubilose to the warm water is 1g:150mL, and immersing for 3.5 hours;
s102, after soaking, placing the soaked product in a micro-jet high-pressure homogenizer for high-pressure homogenization treatment, controlling the working pressure to be 85MPa, and carrying out homogenization treatment for 7min to obtain a homogenized product A for later use;
s103, stewing the homogenized product A obtained in the step S102 in a pot to obtain colloidal cubilose liquid for later use;
s2, microfluid high-pressure homogenization:
weighing 80 parts by weight of cubilose liquid obtained in the step S1 and 3 parts by weight of food-grade hyaluronic acid, placing the cubilose liquid and the food-grade hyaluronic acid together in a microjet high-pressure homogenizer for high-pressure homogenization treatment, controlling the working pressure to be 110MPa, and obtaining a homogenized product B for later use after 15min of homogenization treatment;
s3, concentration:
placing the homogeneous product B obtained in the step S3 in a vacuum drying oven, and performing vacuum drying and concentration treatment at low temperature, wherein the vacuum degree is controlled to be 2.5Pa, the temperature is controlled to be 35 ℃, and the concentration is performed until the water content is 9%, so as to obtain a concentrated solution for later use;
s4, forming:
shaping the concentrated solution obtained in the step S3 by extruding, shredding and slicing to obtain filiform or sheet nidus Collocaliae, and vacuum drying at low temperature to obtain hyaluronic acid beautifying nidus Collocaliae with vacuum degree of 2.5Pa and temperature of 23 deg.C.
Comparative example 2:
the preparation method of the hyaluronic acid facial beautification cubilose comprises the following steps:
s1, preparing the cubilose liquid:
s101, immersing cubilose in warm water at 75 ℃, wherein the weight-volume ratio of the cubilose to the warm water is 1g:150mL, immersing for 3.5 hours, and performing ultrasonic treatment while immersing, wherein the power of ultrasonic is controlled to be 200W, and the frequency of the ultrasonic is controlled to be 25 kHz;
s102, after soaking, putting the mixture into a pot to be stewed to obtain colloidal cubilose liquid for later use;
s2, microfluid high-pressure homogenization:
weighing 80 parts by weight of cubilose liquid obtained in the step S1 and 3 parts by weight of food-grade hyaluronic acid, placing the cubilose liquid and the food-grade hyaluronic acid together in a microjet high-pressure homogenizer for high-pressure homogenization treatment, controlling the working pressure to be 110MPa, and obtaining a homogenized product B for later use after 15min of homogenization treatment;
s3, concentration:
placing the homogeneous product B obtained in the step S3 in a vacuum drying oven, and performing vacuum drying and concentration treatment at low temperature, wherein the vacuum degree is controlled to be 2.5Pa, the temperature is controlled to be 35 ℃, and the concentration is performed until the water content is 9%, so as to obtain a concentrated solution for later use;
s4, forming:
shaping the concentrated solution obtained in the step S3 by extruding, shredding and slicing to obtain filiform or sheet nidus Collocaliae, and vacuum drying at low temperature to obtain hyaluronic acid beautifying nidus Collocaliae with vacuum degree of 2.5Pa and temperature of 23 deg.C.
Comparative example 3:
the preparation method of the hyaluronic acid facial beautification cubilose comprises the following steps:
s1, preparing the cubilose liquid:
s101, immersing cubilose in warm water at 75 ℃, wherein the weight-volume ratio of the cubilose to the warm water is 1g:150mL, immersing for 3.5 hours, and performing ultrasonic treatment while immersing, wherein the power of ultrasonic is controlled to be 200W, and the frequency of the ultrasonic is controlled to be 25 kHz;
s102, after soaking, placing the soaked product in a micro-jet high-pressure homogenizer for high-pressure homogenization treatment, controlling the working pressure to be 85MPa, and carrying out homogenization treatment for 7min to obtain a homogenized product A for later use;
s103, stewing the homogenized product A obtained in the step S102 in a pot to obtain colloidal cubilose liquid for later use;
s2, stirring and uniformly mixing:
weighing 80 parts of cubilose liquid obtained in the step S1 and 3 parts of food-grade hyaluronic acid in corresponding parts by weight, and uniformly mixing to obtain a mixture;
s3, concentration:
placing the mixture obtained in the step S3 in a vacuum drying oven, and performing vacuum drying and concentration treatment at low temperature, wherein the vacuum degree is controlled to be 2.5Pa, the temperature is controlled to be 35 ℃, and the mixture is concentrated until the water content is 9% to obtain a concentrated solution for later use;
s4, forming:
shaping the concentrated solution obtained in the step S3 by extruding, shredding and slicing to obtain filiform or sheet nidus Collocaliae, and vacuum drying at low temperature to obtain hyaluronic acid beautifying nidus Collocaliae with vacuum degree of 2.5Pa and temperature of 23 deg.C.
Comparative example 4:
the preparation method of the hyaluronic acid facial beautification cubilose comprises the following steps:
s1, preparing the cubilose liquid:
s101, immersing cubilose in warm water at 75 ℃, wherein the weight-volume ratio of the cubilose to the warm water is 1g:150mL, immersing for 3.5 hours, and performing ultrasonic treatment while immersing, wherein the power of ultrasonic is controlled to be 200W, and the frequency of the ultrasonic is controlled to be 25 kHz;
s102, after soaking, placing the soaked product in a micro-jet high-pressure homogenizer for high-pressure homogenization treatment, controlling the working pressure to be 85MPa, and carrying out homogenization treatment for 7min to obtain a homogenized product A for later use;
s103, stewing the homogenized product A obtained in the step S102 in a pot to obtain colloidal cubilose liquid for later use;
s2, microfluid high-pressure homogenization:
weighing 80 parts by weight of the cubilose liquid obtained in the step S1, placing the cubilose liquid in a micro-jet high-pressure homogenizer for high-pressure homogenization treatment, controlling the working pressure to be 110MPa, and carrying out homogenization treatment for 15min to obtain a homogenized product B for later use;
s3, concentration:
placing the homogeneous product B obtained in the step S3 in a vacuum drying oven, and performing vacuum drying and concentration treatment at low temperature, wherein the vacuum degree is controlled to be 2.5Pa, the temperature is controlled to be 35 ℃, and the concentration is performed until the water content is 9%, so as to obtain a concentrated solution for later use;
s4, forming:
shaping the concentrated solution obtained in the step S3 by extruding, shredding and slicing to obtain filiform or sheet nidus Collocaliae, and vacuum drying at low temperature to obtain hyaluronic acid beautifying nidus Collocaliae with vacuum degree of 2.5Pa and temperature of 23 deg.C.
Comparative example 5:
the preparation method of the hyaluronic acid facial beautification cubilose comprises the following steps:
s1, preparing the cubilose liquid:
s101, immersing cubilose in warm water at 75 ℃, wherein the weight-volume ratio of the cubilose to the warm water is 1g:150mL, immersing for 3.5 hours, and performing ultrasonic treatment while immersing, wherein the power of ultrasonic is controlled to be 200W, and the frequency of the ultrasonic is controlled to be 25 kHz;
s102, after soaking, placing the soaked product in a micro-jet high-pressure homogenizer for high-pressure homogenization treatment, controlling the working pressure to be 85MPa, and carrying out homogenization treatment for 7min to obtain a homogenized product A for later use;
s103, placing the homogenized product A obtained in the step S102 into a pot to be stewed to obtain colloidal cubilose liquid for later use;
s2, concentration:
placing the cubilose liquid obtained in the step S3 in a vacuum drying oven, and performing vacuum drying and concentration treatment at low temperature, wherein the vacuum degree is controlled to be 2.5Pa, the temperature is controlled to be 35 ℃, and the concentration is performed until the water content is 9%, so as to obtain a concentrated solution for later use;
s3, forming:
shaping the concentrated solution obtained in the step S2 by extruding, shredding and slicing to obtain filiform or sheet nidus Collocaliae, and vacuum drying at low temperature to obtain hyaluronic acid beautifying nidus Collocaliae with vacuum degree of 2.5Pa and temperature of 23 deg.C.
Comparative example 6:
the preparation method of the hyaluronic acid facial beautification cubilose comprises the following steps:
s1, preparing the cubilose liquid:
s101, immersing cubilose in warm water at 75 ℃, wherein the weight-volume ratio of the cubilose to the warm water is 1g:150mL, immersing for 3.5 hours, and performing ultrasonic treatment while immersing, wherein the power of ultrasonic is controlled to be 200W, and the frequency of the ultrasonic is controlled to be 25 kHz;
s102, after soaking, placing the soaked product in a micro-jet high-pressure homogenizer for high-pressure homogenization treatment, controlling the working pressure to be 85MPa, and carrying out homogenization treatment for 7min to obtain a homogenized product A for later use;
s103, stewing the homogenized product A obtained in the step S102 in a pot to obtain colloidal cubilose liquid for later use;
s2, microfluid high-pressure homogenization:
and (4) weighing 80 parts by weight of cubilose liquid obtained in the step S1 and 3 parts by weight of food-grade hyaluronic acid, placing the cubilose liquid and the food-grade hyaluronic acid together in a micro-jet high-pressure homogenizer for high-pressure homogenization treatment, controlling the working pressure to be 110MPa, obtaining a homogenized product B after the homogenization treatment for 15min, shaping the homogenized product B in a filament extruding, filament cutting and slicing mode to form filament-shaped or sheet-shaped cubilose, and drying the filament-shaped or sheet-shaped cubilose.
In order to compare the technical effects of the application, the hyaluronic acid beautifying cubilose is correspondingly prepared by the methods of the embodiment 2 and the comparative examples 1-6 respectively, and then the oxidation resistance is tested.
The method comprises the following specific steps:
experimental animals: SPF grade mice purchased from the animal testing center, university of wuhan.
Experiment:
(1) after the purchased SPF-level mice are adaptively fed for 7 days, randomly dividing the SPF-level mice into 7 groups with equal quality and quantity, wherein each group comprises 20 mice, each half of male and female, then correspondingly preparing the hyaluronic acid facial beautification bird's nest by adopting the method of the embodiment 2 and the comparative examples 1-6 to correspondingly irrigate the stomachs of the mice in each group, wherein the stomach irrigation time is 9:00-9:30 in the morning of each day, the stomach irrigation is continuously performed for 4 weeks, and all the mice freely drink water during the experiment period;
(2) fasting for 12h after the last gastric lavage of the mouse, freely drinking water, taking blood from eyeballs, placing the blood into a centrifugal tube containing 1% heparin sodium, centrifuging for 15min at 4 ℃ and 5000rpm, and collecting plasma;
(3) and (3) according to the SOD kit, measuring the SOD activity of each group of experimental mice by using the blood plasma prepared in the step (2), and counting the experimental results.
The specific experimental comparative data are shown in table 1 below:
TABLE 1
As can be seen from the above table 1, when the example 2 is compared with the comparative examples 1 to 6, the serum SOD content of the mice in the example 2 group is obviously higher than that in the comparative examples 1 to 6, the effects of wrinkle resistance, aging resistance and facial beautification are good, and the mice in both sexes show more remarkable facial beautification effect.
Claims (10)
1. The preparation method of the hyaluronic acid facial beautification cubilose is characterized by comprising the following steps:
s1, preparing the cubilose liquid:
s101, immersing cubilose in warm water, performing immersion treatment for 3-4 hours, and performing ultrasonic treatment while immersing;
s102, after soaking, placing the mixture in a micro-jet high-pressure homogenizer for high-pressure homogenization, and obtaining a homogenized product A for later use;
s103, stewing the homogenized product A obtained in the step S102 in a pot to obtain colloidal cubilose liquid for later use;
s2, microfluid high-pressure homogenization:
weighing 70-90 parts by weight of the cubilose liquid obtained in the step S1 and 2-4 parts by weight of food-grade hyaluronic acid, and placing the cubilose liquid and the food-grade hyaluronic acid together in a micro-jet high-pressure homogenizer for high-pressure homogenization treatment to obtain a homogenized product B for later use;
s3, concentration:
placing the homogeneous product B obtained in the step S3 in a vacuum drying oven, and performing vacuum drying and concentration treatment under a low-temperature condition to obtain a concentrated solution for later use;
s4, forming:
and (5) shaping the concentrated solution obtained in the step (S3) in a filament extruding, filament cutting and slicing mode to form filament or sheet bird 'S nest, and then carrying out low-temperature vacuum drying to obtain the hyaluronic acid beauty bird' S nest.
2. The preparation of claim 1, wherein the weight-to-volume ratio of the cubilose and the warm water in the step S101 is 1g: 100-200 mL.
3. The preparation of hyaluronic acid beauty bird' S nest of claim 1, wherein the temperature in the warm water is controlled to be 70-80 ℃ during the soaking treatment in step S101.
4. The preparation of claim 1, wherein the ultrasonic treatment in step S101 is performed under a power of 100-300W and a frequency of 20-30 kHz.
5. The preparation method of claim 1, wherein the high pressure homogenization treatment in step S102 is performed under a working pressure of 80-90 MPa for 5-9 min.
6. The preparation of claim 1, wherein the homogenization treatment at step S2 is carried out under a working pressure of 100-120 MPa for 12-18 min.
7. The preparation method of claim 1, wherein the degree of vacuum of the step S3 is controlled to 2-3 Pa, the temperature is controlled to 30-40 ℃, and the mixture is concentrated to a water content of 8-10%.
8. The preparation of claim 1, wherein the low-temperature vacuum drying treatment in step S4 is performed under a vacuum degree of 2-3 Pa and at a temperature of 20-26 ℃.
9. A hyaluronic acid facial beautification cubilose which is characterized by being prepared according to any one method of claims 1 to 7.
10. The hyaluronic acid beautifying bird's nest of claim 9, which is a ready-to-eat food.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210570015.6A CN114903171A (en) | 2022-05-24 | 2022-05-24 | Hyaluronic acid beautifying bird's nest and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210570015.6A CN114903171A (en) | 2022-05-24 | 2022-05-24 | Hyaluronic acid beautifying bird's nest and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN114903171A true CN114903171A (en) | 2022-08-16 |
Family
ID=82769165
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210570015.6A Pending CN114903171A (en) | 2022-05-24 | 2022-05-24 | Hyaluronic acid beautifying bird's nest and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114903171A (en) |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104886589A (en) * | 2015-07-08 | 2015-09-09 | 周川 | Cubilose product and preparation method thereof |
| CN105013770A (en) * | 2015-07-15 | 2015-11-04 | 广州易沁企业管理咨询有限公司 | Method for cleaning cubilose |
| CN105125582A (en) * | 2015-09-28 | 2015-12-09 | 极燕生物有限公司 | Fast-food bird nest and preparation method thereof |
| CN105146521A (en) * | 2015-09-28 | 2015-12-16 | 极燕生物有限公司 | Convenient fast food type cubilose and preparing method thereof |
| WO2016183789A1 (en) * | 2015-05-19 | 2016-11-24 | 陈天煌 | Composition extracted from bird's nest, and food comprising composition extracted from bird's nest |
| CN107969691A (en) * | 2017-11-28 | 2018-05-01 | 北京同仁堂健康药业股份有限公司 | A kind of composition that can effectively improve moisture of skin and preparation method thereof |
| CN108851065A (en) * | 2018-09-10 | 2018-11-23 | 大连臻理海洋科技有限公司 | Anti-decrepit beauty food |
-
2022
- 2022-05-24 CN CN202210570015.6A patent/CN114903171A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016183789A1 (en) * | 2015-05-19 | 2016-11-24 | 陈天煌 | Composition extracted from bird's nest, and food comprising composition extracted from bird's nest |
| CN104886589A (en) * | 2015-07-08 | 2015-09-09 | 周川 | Cubilose product and preparation method thereof |
| CN105013770A (en) * | 2015-07-15 | 2015-11-04 | 广州易沁企业管理咨询有限公司 | Method for cleaning cubilose |
| CN105125582A (en) * | 2015-09-28 | 2015-12-09 | 极燕生物有限公司 | Fast-food bird nest and preparation method thereof |
| CN105146521A (en) * | 2015-09-28 | 2015-12-16 | 极燕生物有限公司 | Convenient fast food type cubilose and preparing method thereof |
| CN107969691A (en) * | 2017-11-28 | 2018-05-01 | 北京同仁堂健康药业股份有限公司 | A kind of composition that can effectively improve moisture of skin and preparation method thereof |
| CN108851065A (en) * | 2018-09-10 | 2018-11-23 | 大连臻理海洋科技有限公司 | Anti-decrepit beauty food |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101787078B (en) | Collagen polypeptide, preparation method and application thereof | |
| CN102113991B (en) | Toning lotion containing pearl water extract and preparation method | |
| CN103462879B (en) | There is the tremella mud of moist effect, facial film and preparation method thereof | |
| CN109170469A (en) | A kind of Isin glue collagen peptide solid beverage and preparation method thereof | |
| CN107164442B (en) | Collagen polypeptide and application thereof | |
| CN105901539A (en) | Blood-activating and beautifying fruity jujube-containing crushed beef ball and preparation method thereof | |
| CN103976203B (en) | Jelly of a kind of beautifying face and moistering lotion and preparation method thereof | |
| CN101664373A (en) | Donkey milk cosmetic and preparation method thereof | |
| CN107281082A (en) | A kind of nutrient solution containing small-molecular peptides and the facial mask and preparation method including it | |
| CN101849681B (en) | Nutrient chicken skin jelly and preparation method thereof | |
| CN104206641A (en) | Megalobatrachus protein polypeptide powder and preparation method thereof | |
| CN101912132A (en) | Collagen beverage and preparation method thereof | |
| CN103976202B (en) | A kind of edible collagen protein jelly and preparation method thereof | |
| CN102511890A (en) | Jellyfish beverage | |
| CN103251548A (en) | Selenium-enriched watermelon and egg white mask cream | |
| CN104928112A (en) | Fruit wine | |
| CN103976205A (en) | Jelly for improving internal secretion and preparation method of jelly | |
| CN114903171A (en) | Hyaluronic acid beautifying bird's nest and preparation method thereof | |
| CN103976211B (en) | Jelly of a kind of fat-reducing and preparation method thereof | |
| CN105533119B (en) | A kind of preparation method of fruity acid gel | |
| CN107348475A (en) | Chinese-wolfberry nutritive bean vermicelli and its preparation technology | |
| CN109453078B (en) | Bionic matrix hydrogel mask and preparation method thereof | |
| CN1251667C (en) | Shampoo cream containing yerbadetajo herb and method for preparing the same | |
| CN102845760A (en) | Duck blood polypeptide nutrient sausage and its preparation method | |
| CN108450726A (en) | A kind of multi-strain fermentation type brown sugar vinegar beverage and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |