CN114887530A - Liquid preparation process and liquid preparation system for gene detection kit - Google Patents

Liquid preparation process and liquid preparation system for gene detection kit Download PDF

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Publication number
CN114887530A
CN114887530A CN202210411155.9A CN202210411155A CN114887530A CN 114887530 A CN114887530 A CN 114887530A CN 202210411155 A CN202210411155 A CN 202210411155A CN 114887530 A CN114887530 A CN 114887530A
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China
Prior art keywords
tubular
fixing
kit
plate
hole
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Granted
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CN202210411155.9A
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CN114887530B (en
Inventor
曹逸然
吴烨
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Xinjiang Jinyu Medical Laboratory Co ltd
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Yixing Baiao Precision Nuclear Biotechnology Co ltd
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Priority to CN202210411155.9A priority Critical patent/CN114887530B/en
Publication of CN114887530A publication Critical patent/CN114887530A/en
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/20Mixing the contents of independent containers, e.g. test tubes
    • B01F31/201Holders therefor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/20Mixing the contents of independent containers, e.g. test tubes
    • B01F31/24Mixing the contents of independent containers, e.g. test tubes the containers being submitted to a rectilinear movement
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The invention discloses a liquid preparation process and a liquid preparation system for a gene detection kit, and belongs to the technical field of gene detection. A liquid preparation system for a gene detection kit comprises a bottom plate and further comprises: vibrate the mechanism, set up in the bottom plate top, wherein, vibrate the mechanism and include: the driving motor is connected to the top of the bottom plate through a supporting frame; the transmission assembly is arranged at the output end of the driving motor; the guide assembly is arranged at the top of the bottom plate and is matched with the transmission assembly to achieve the effect of oscillation; the supporting plate is arranged at the top of the oscillating mechanism; the adjusting frame is arranged at the top of the supporting plate; the fixed tray is arranged on the outer wall of the adjusting frame and matched with the supporting plate; the adjusting and fixing component is arranged inside the through hole; the tubular reagent box fixing device is simple in structure and convenient to operate, can fully and effectively mix and shake reagents in the reagent box, is convenient for limiting and fixing tubular reagent boxes of different types and sizes, is simple and convenient to fix and use, and can effectively improve the working efficiency.

Description

Liquid preparation process and liquid preparation system for gene detection kit
Technical Field
The invention relates to the technical field of gene detection, in particular to a liquid preparation process and a liquid preparation system for a gene detection kit.
Background
The gene is a genetic basic unit, carries a DNA or RNA sequence of genetic information, transfers the genetic information to the next generation through replication, and guides the synthesis of protein to express the genetic information carried by the gene, thereby controlling the character expression of an organism individual. The gene detection is a technique for detecting DNA by blood, other body fluids or cells, and is a method for taking peripheral venous blood or other tissue cells of a detected person, amplifying the gene information, detecting DNA molecular information in the cells of the detected person by a specific device, and analyzing whether the gene type, the gene defect and the expression function contained in the DNA molecular information are normal or not, so that people can know the gene information of themselves, and the etiology is determined or the risk of a certain disease of the body is predicted.
Reagents for gene detection are usually contained in a tubular kit, and the reagents in the tubular kit are often required to be mixed and shaken up to prepare a solution in the using process.
Through retrieval, the Chinese utility model with the publication number of CN215288725U discloses a liquid preparation device for a gene detection kit, which comprises a bottom plate and a driving motor, wherein supporting legs are fixed at four corners of the bottom plate, a crank and an outer sheave are rotationally connected to the top surface of the bottom plate, the crank is in meshing transmission with the outer sheave, and the center of the top of the outer sheave is in transmission connection with a turntable through a transmission shaft; the top surface of the turntable is uniformly provided with a plurality of placing holes which are arranged in an arc shape, and the diameters of the placing holes are reduced from large to small; in the using process, the outer groove wheel can be driven to intermittently rotate by the rotary driving mechanism so as to drive the tubular kit on the rotary table to intermittently swing, so that the aim of oscillating and dispensing the liquid is fulfilled, and compared with the traditional operation mode, the manual labor can be saved; meanwhile, the arrangement of the plurality of placing holes enables the tubular reagent boxes to synchronously oscillate, so that the working efficiency is improved; the diameter of the placing hole is also provided with various sizes, so that the placing hole can be suitable for tubular kits with various sizes, and the universality is good; although the device can save manpower to a certain extent and improve the working efficiency, the device still has certain defects, firstly, the tubular reagent box is rotated only by intermittent rotation, the oscillation effect is not ideal, and the reagents in the reagent box are difficult to be mixed and shaken uniformly; secondly, although the placing holes are provided with various diameters, the placing holes can only be suitable for tubular reagent kits with the same model, and the tubular reagent kits with different models can not be fixed by the same placing hole; thirdly, the tubular kit is fixed in the placing hole, and the operation is troublesome, so that the device still has certain defects.
Disclosure of Invention
The invention aims to solve the problems in the prior art and provides a liquid preparation process and a liquid preparation system for a gene detection kit.
In order to achieve the purpose, the invention adopts the following technical scheme:
a liquid preparation system for a gene detection kit comprises a bottom plate and further comprises:
the oscillation mechanism is arranged at the top of the bottom plate and is used for oscillating and mixing the tubular reagent kit,
wherein, vibrate the mechanism and include:
the driving motor is connected to the top of the bottom plate through a supporting frame;
the transmission assembly is arranged at the output end of the driving motor;
the guide assembly is arranged at the top of the bottom plate and is matched with the transmission assembly to achieve the effect of oscillation;
the support plate is arranged at the top of the oscillating mechanism and used for supporting the bottom of the tubular kit;
the adjusting frame is arranged at the top of the supporting plate;
the fixed tray is arranged on the outer wall of the adjusting frame and matched with the supporting plate;
wherein the top of the supporting plate is provided with a groove matched with the tubular kit, the fixed tray is provided with a through hole matched with the tubular kit, the groove corresponds to the through hole,
and the adjusting and fixing assembly is arranged inside the through hole and used for limiting and fixing the tubular kits of different models.
As the preferred technical scheme of this application, transmission assembly includes the carousel, be provided with the axle sleeve through connecting block off-centre on the carousel outer wall, the axle sleeve cooperatees with the direction subassembly, be connected with the link on the axle sleeve outer wall, the backup pad set up in the link top.
As the preferred technical scheme of this application, the direction subassembly is including connecting in the fixed column at bottom plate top, it is connected with first connecting plate to rotate on the fixed column outer wall, the one end that the fixed column was kept away from to first connecting plate is connected with the slide bar, axle sleeve sliding connection in the slide bar outer wall.
As the preferred technical scheme of this application, the alignment jig including connect in guide post, the lead screw at backup pad top, set up in the mounting panel at guide post top, fixed tray threaded connection in on the lead screw outer wall and with the guide post slip link to each other, the mounting panel is passed and the hand wheel is connected to the one end of lead screw.
As the preferred technical scheme of this application, be provided with the recess with tubulose kit matched with in the backup pad, it has the through-hole with tubulose kit matched with to open the chisel on the fixed tray, just the recess is corresponding with the through-hole.
As the preferred technical scheme of this application, it includes the solid fixed ring of first solid fixed ring and second to adjust fixed subassembly, first solid fixed ring through first spring set up in on the through-hole inner wall, the solid fixed ring of second passes through adjusting part and sets up inside the through-hole.
As the preferred technical scheme of this application, adjusting part includes second connecting plate, spliced pole and second spring, the cavity has been seted up to fixed tray inside, second connecting plate sliding connection is inside the cavity, spliced pole one end is connected in second connecting plate outer wall, and the other end is connected with the solid fixed ring of second, the second spring sets up between second connecting plate and fixed tray inner wall.
As the preferred technical scheme of this application, the second connecting plate is provided with the multiunit with the through-hole cooperation, the second spring sets up in outermost a set of between second connecting plate and the fixed tray inner wall, outermost a set of be connected with the pull ring through the connecting rod on the second connecting plate outer wall.
As the preferred technical scheme of this application, first solid fixed ring and the solid fixed ring of second all adopt flexible rubber material, just first solid fixed ring cooperatees with the solid fixed ring of second.
A liquid preparation process for a gene detection kit specifically comprises the following steps:
s1: the height of the fixed tray is adjusted according to the size of the model length of the tubular kit, the fixed tray is adjusted to enable the bottom of the tubular kit to be abutted against the groove, and the fixed tray is located at the height of two thirds of the tubular kit;
s2: when the height of the fixed tray is adjusted, the hand wheel is rotated to drive the lead screw connected with the fixed tray to rotate, the arranged slide bars are used, and further, when the hand wheel is rotated to drive the lead screw to rotate, the fixed tray can move up and down along the slide bars, so that the fixed tray can move to enable the bottom of the tubular kit to be abutted against the grooves and is located at the height of two thirds of the tubular kit, the tubular kit can be conveniently fixed, a plurality of groups of reagents are correspondingly arranged through the grooves and the through holes in a matched mode, and further, the reagents can be simultaneously vibrated, mixed and uniformly, labor can be saved, and the working efficiency can be improved;
s3: the pulling ring is pulled to drive the connecting rod and the second connecting plate which are connected with the pulling ring to move, so that the second spring is compressed, and the second fixing ring is driven to move towards the inside of the through hole, so that the tubular kit to be vibrated and mixed is conveniently placed in the through hole, the tubular kit is inserted into the through hole, the pulling ring is loosened to drive the second connecting plate to return to the original state under the action of the elastic force of the second spring, so that the second fixing ring is driven to move towards the center of the through hole, when the pulling ring abuts against the tubular kit in due course, the first spring can bear certain pressure, so that the first fixing ring and the second fixing ring both tightly abut against the tubular kit, and the first spring, the second spring, the first fixing ring and the second fixing ring can conveniently and quickly play a role in positioning the tubular kit, the operation is simple and the use is convenient, the working efficiency can be improved to a certain extent;
s4: the distance between the first fixing ring and the second fixing ring can be adjusted through the adjusting and fixing assembly, so that tubular kits of different models can be fixed, various tubular kits of different models and sizes can be realized, and the universality of the device is improved;
s5: the driving motor is started to drive the turntable connected with the output end of the driving motor to rotate, and the outer wall of the driving motor is eccentrically provided with the shaft sleeve through the connecting block, and the bottom plate is provided with the fixed column, the first connecting plate and the sliding rod which are matched with the bottom plate, so that when the driving motor is started, the shaft sleeve can be driven to swing along the fixed column and can also slide up and down along the sliding rod;
s6: when the axle sleeve swings along the fixed column and slides up and down along the slide bar, the axle sleeve can drive the supporting plate and the fixed tray to swing and move up and down, and then the tubular reagent box on the fixed tray is driven to swing and move up and down, so that a good vibration effect is achieved on the reagents in the tubular reagent box, manpower can be effectively saved, labor intensity is reduced, and the reagents in the tubular reagent box can be fully mixed and uniformly shaken.
Compared with the prior art, the invention provides a liquid preparation system for a gene detection kit, which has the following beneficial effects:
1. this gene detect reagent box is with joining in marriage liquid system through the vibration mechanism that sets up, tubular reagent box on the fixed tray swings and reciprocates to play good vibration effect to the reagent in the tubular reagent box, can effectively save the manpower, reduce intensity of labour, can be abundant again mix shake even to the reagent in the tubular reagent box, solved among the prior art vibration effect not ideal, be difficult to abundant mix shake even with the reagent in the reagent box.
2. This gene detect reagent box is with joining in marriage liquid system through the fixed subassembly of regulation that sets up for same through-hole can be fixed the tubulose kit of multiunit different models, and the commonality is strong, has solved and has placed the hole and only can be applicable to the tubulose kit rather than the same model, and the same hole of placing is difficult to the condition of fixing the tubulose kit of different models.
3. This gene detect reagent box is with joining in marriage liquid system through adjusting part, can be convenient fix tubular kit, easy operation, practical convenient, improvement work efficiency that can be further.
4. This gene detect reagent box is with joining in marriage liquid system through the alignment jig that sets up, can adjust the height of fixed tray, makes its bottom and the recess that can satisfy the tubulose reagent box offset, and fixed tray is located tubulose reagent box two-thirds department height to the geminate transistor changes the reagent box and plays stable fixed effect.
5. This gene detect reagent box is with joining in marriage liquid system corresponds the cooperation through recess and through-hole and is provided with the multiunit, and then can vibrate simultaneously to multiunit reagent and mix and shake evenly, can use manpower sparingly can improve work efficiency again.
6. This gene detect reagent box is with joining in marriage liquid system all adopts flexible rubber material through first solid fixed ring and the solid fixed ring of second, consequently when pressing from both sides the fastening to tubular reagent box, can avoid causing the condition of damage to it, improves the performance of device.
Drawings
FIG. 1 is a first schematic structural diagram of a solution preparation system for a gene detection kit according to the present invention.
FIG. 2 is a second schematic structural diagram of a liquid preparation system for a gene detection kit according to the present invention.
FIG. 3 is a front view of a liquid preparation system for a gene detection kit according to the present invention.
FIG. 4 is a side view of a dispensing system for a gene assaying kit according to the present invention.
FIG. 5 is a first schematic structural diagram of a shaking mechanism in a fluid dispensing system for a gene detection kit according to the present invention.
FIG. 6 is a second schematic structural diagram of a shaking mechanism in a fluid dispensing system for a gene detection kit according to the present invention.
FIG. 7 is a schematic structural view of a fixing tray in a liquid preparation system for a gene detection kit according to the present invention.
FIG. 8 is a schematic view of the internal structure of a fixing tray in a solution preparation system for a gene detection kit according to the present invention.
FIG. 9 is a top view of the internal structure of a fixing tray in a dispensing system for a gene detection kit according to the present invention.
In the figure:
100. a base plate; 101. a support frame; 200. a vibrating mechanism; 300. a drive motor; 400. a transmission assembly; 401. a turntable; 402. a shaft sleeve; 403. a connecting frame; 500. a guide assembly; 501. fixing a column; 502. a first connecting plate; 503. a slide bar; 600. a support plate; 601. a groove; 700. an adjusting bracket; 701. a guide post; 702. a lead screw; 703. mounting a plate; 704. a hand wheel; 800. fixing the tray; 801. a through hole; 900. adjusting the fixing component; 901. a first retaining ring; 902. a second retaining ring; 903. a first spring; 904. an adjustment assembly; 905. a second connecting plate; 906. connecting columns; 907. a second spring; 908. a connecting rod; 909. and (4) a pull ring.
Detailed Description
The technical solution in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention; it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments, and all other embodiments obtained by those skilled in the art without any inventive work are within the scope of the present invention.
In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "top/bottom", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and thus should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "disposed," "sleeved/connected," "connected," and the like are to be construed broadly, e.g., "connected," which may be fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; the two components can be directly connected or indirectly connected through an intermediate medium, and the two components can be communicated with each other; the specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
Example 1:
referring to fig. 1 to 9, a liquid preparation system for a gene detection kit includes a base plate 100, and further includes:
a vibrating mechanism 200 disposed on the top of the bottom plate 100 for vibrating and mixing the tubular reagent cartridges,
wherein, vibrate mechanism 200 includes:
the driving motor 300 is connected to the top of the bottom plate 100 through a supporting frame 101;
the transmission assembly 400 is arranged at the output end of the driving motor 300;
the guide assembly 500 is arranged at the top of the bottom plate 100 and is matched with the transmission assembly 400 to achieve the oscillation effect;
the supporting plate 600 is arranged at the top of the oscillating mechanism 200 and used for supporting the bottom of the tubular kit;
an adjusting bracket 700 disposed on the top of the supporting plate 600;
a fixing tray 800 disposed on an outer wall of the adjusting bracket 700 and engaged with the supporting plate 600;
through the vibration mechanism 200 that sets up, tubular reagent box on the fixed tray 800 swings and reciprocates to play good vibration effect to the reagent in the tubular reagent box, can effectively save the manpower, reduce intensity of labour, can be abundant again mix to shake even to the reagent in the tubular reagent box, solved among the prior art oscillation effect not ideal, be difficult to abundant mix to shake even with the reagent in the reagent box.
Wherein, the top of the supporting plate 600 is provided with a groove 601 matching with the tubular reagent kit, the fixed tray 800 is provided with a through hole 801 matching with the tubular reagent kit, the groove 601 corresponds to the through hole 801,
and the adjusting and fixing component 900 is arranged inside the through hole 801 and used for limiting and fixing the tubular kits of different models.
Referring to fig. 2-6, the driving assembly 400 includes a rotating disc 401, a shaft sleeve 402 is eccentrically disposed on an outer wall of the rotating disc 401 through a connecting block, the shaft sleeve 402 is matched with the guiding assembly 500, a connecting frame 403 is connected to an outer wall of the shaft sleeve 402, a supporting plate 600 is disposed on the top of the connecting frame 403, and the connecting frame 403 can swing and lift through the driving assembly 400 and the guiding assembly 500.
Referring to fig. 3-6, the guiding assembly 500 includes a fixing post 501 connected to the top of the base plate 100, a first connecting plate 502 is rotatably connected to an outer wall of the fixing post 501, a sliding rod 503 is connected to an end of the first connecting plate 502 far away from the fixing post 501, and the shaft sleeve 402 is slidably connected to an outer wall of the sliding rod 503.
Referring to fig. 1-3, the adjusting bracket 700 includes a guide post 701 connected to the top of the supporting plate 600, a screw 702, and a mounting plate 703 arranged at the top of the guide post 701, the fixing tray 800 is connected to the outer wall of the screw 702 in a threaded manner and is connected to the guide post 701 in a sliding manner, one end of the screw 702 penetrates through the mounting plate 703 and is connected to a hand wheel 704, and the height of the fixing tray 800 can be adjusted through the adjusting bracket 700, so that the bottom of the tubular kit can be abutted to the groove 601, and the fixing tray 800 is located at the height of two thirds of the tubular kit, thereby achieving a stable fixing effect on the tubular kit.
Referring to fig. 2 and 9, a groove 601 matched with the tubular reagent kit is formed in the support plate 600, a through hole 801 matched with the tubular reagent kit is drilled in the fixing tray 800, the groove 601 corresponds to the through hole 801, and the groove 601 and the through hole 801 correspond to each other, so that stability of the tubular reagent kit in the oscillation process is ensured.
Referring to fig. 7-8, the adjusting and fixing assembly 900 comprises a first fixing ring 901 and a second fixing ring 902, the first fixing ring 901 is arranged on the inner wall of the through hole 801 through a first spring 903, the second fixing ring 902 is arranged inside the through hole 801 through an adjusting assembly 904, and the adjusting and fixing assembly 900 is arranged, so that the same through hole 801 can fix a plurality of groups of tubular kits of different models, the universality is strong, the problem that the placing hole can only be suitable for the tubular kits of the same model is solved, and the situation that the tubular kits of different models are difficult to fix through the same placing hole is solved.
Referring to fig. 7-9, adjusting part 904 includes second connecting plate 905, spliced pole 906 and second spring 907, the inside cavity of having seted up of fixed tray 800, second connecting plate 905 sliding connection is inside the cavity, spliced pole 906 one end is connected in second connecting plate 905 outer wall, the other end is connected with the solid fixed ring 902 of second, second spring 907 sets up between second connecting plate 905 and fixed tray 800 inner wall, through adjusting part 904, can be convenient fix the tubulose kit, and is simple in operation, practical convenient, improvement work efficiency that can be further.
Referring to fig. 7-9, the second connection plates 905 are provided with a plurality of sets in cooperation with the through holes 801, the second springs 907 are disposed between the outermost set of second connection plates 905 and the inner wall of the fixed tray 800, and the outer walls of the outermost set of second connection plates 905 are connected with pull rings 909 through connecting rods 908, so that the feasibility of the device is ensured.
Referring to fig. 8-9, the first fixing ring 901 and the second fixing ring 902 are made of flexible rubber, the first fixing ring 901 is matched with the second fixing ring 902, and the first fixing ring 901 and the second fixing ring 902 are made of flexible rubber, so that when the tubular kit is clamped and fastened, the tubular kit can be prevented from being damaged, and the use performance of the device is improved.
Specifically, this gene detect reagent box is with joining in marriage liquid system during operation/use:
firstly, adjusting the height of the fixed tray 800 according to the size of the model length of the tubular kit, adjusting the height of the fixed tray until the bottom of the tubular kit is abutted against the groove 601, and enabling the fixed tray 800 to be located at the height of two thirds of the tubular kit;
when the height of the fixed tray 800 is adjusted, the hand wheel 704 is rotated to drive the lead screw 702 connected with the hand wheel to rotate, and the fixed tray 800 can move up and down along the slide bar 503 through the arranged slide bar 503 and further move to enable the bottom of the tubular kit to be abutted against the groove 601 when the hand wheel 704 is rotated to drive the lead screw 702 to rotate, and the fixed tray is located at the two-thirds height of the tubular kit, so that the tubular kit can be conveniently fixed, a plurality of groups of reagents are correspondingly matched and arranged through the groove 601 and the through hole 801, and further the plurality of groups of reagents can be simultaneously vibrated, mixed and evenly, so that manpower can be saved and the working efficiency can be improved;
pulling the pull ring 909 to drive the connecting rod 908 and the second connecting plate 905 connected with the pull ring 909 to move, so as to compress the second spring 907 and simultaneously drive the second fixing ring 902 to move towards the inside of the through hole 801, so as to conveniently place the tubular kit to be vibrated and mixed into the through hole 801, inserting the tubular kit into the through hole 801, loosening the pull ring 909 to drive the second connecting plate 905 to return to the original state under the action of the elastic force of the second spring 907, so as to drive the second fixing ring 902 to move towards the center of the through hole 801, when offsetting against the tubular kit in due course, the first spring 903 can bear a certain pressure, so that the first fixing ring 901 and the second fixing ring 902 both abut against the tubular kit tightly, and further the first spring 903, the second spring 907, the first fixing ring 901 and the second fixing ring 902 can have a positioning effect on the tubular kit conveniently and quickly, the operation is simple, the use is convenient, and the working efficiency can be improved to a certain degree;
through the arranged adjusting and fixing assembly 900, the distance between the first fixing ring 901 and the second fixing ring 902 can be adjusted, so that tubular kits of different models can be fixed, tubular kits of various models and sizes can be realized, and the universality of the device is improved;
the driving motor 300 is started to drive the turntable 401 connected with the output end of the driving motor to rotate, and as the shaft sleeve 402 is eccentrically arranged on the outer wall of the driving motor 300 through the connecting block, and the fixing column 501, the first connecting plate 502 and the sliding rod 503 which are matched with the bottom plate 100 are arranged on the bottom plate 100, the driving motor 300 can drive the shaft sleeve 402 to swing along the fixing column 501 and simultaneously slide up and down along the sliding rod 503;
when the shaft sleeve 402 swings along the fixing column 501 and slides up and down along the sliding rod 503, the supporting plate 600 and the fixing tray 800 are driven to swing and move up and down, and then the tubular reagent box on the fixing tray 800 is driven to swing and move up and down, so that a good vibration effect is achieved on the reagents in the tubular reagent box, manpower can be effectively saved, labor intensity is reduced, and the reagents in the tubular reagent box can be fully mixed and uniformly shaken.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.

Claims (10)

1. The utility model provides a gene detection kit is with joining in marriage liquid system, includes bottom plate (100), its characterized in that still includes:
the oscillation mechanism (200) is arranged at the top of the bottom plate (100) and is used for oscillating and mixing the tubular reagent kit,
wherein the oscillating mechanism (200) comprises:
the driving motor (300) is connected to the top of the bottom plate (100) through a supporting frame (101);
the transmission assembly (400) is arranged at the output end of the driving motor (300);
the guide assembly (500) is arranged at the top of the bottom plate (100) and is matched with the transmission assembly (400) to achieve the oscillating effect;
the supporting plate (600) is arranged at the top of the oscillating mechanism (200) and is used for supporting the bottom of the tubular reagent kit;
an adjusting bracket (700) arranged on the top of the supporting plate (600);
the fixed tray (800) is arranged on the outer wall of the adjusting frame (700) and is matched with the supporting plate (600);
wherein, the top of the supporting plate (600) is provided with a groove (601) matched with the tubular reagent kit, the fixed tray (800) is provided with a through hole (801) matched with the tubular reagent kit, the groove (601) corresponds to the through hole (801),
and the adjusting and fixing assembly (900) is arranged inside the through hole (801) and is used for limiting and fixing the tubular kits of different models.
2. The fluid distribution system for the seed gene detection kit according to claim 1, wherein the transmission assembly (400) comprises a rotary plate (401), a shaft sleeve (402) is eccentrically arranged on the outer wall of the rotary plate (401) through a connecting block, the shaft sleeve (402) is matched with the guide assembly (500), a connecting frame (403) is connected on the outer wall of the shaft sleeve (402), and the support plate (600) is arranged at the top of the connecting frame (403).
3. The fluid distribution system for the seed gene detection kit according to claim 2, wherein the guide assembly (500) comprises a fixed column (501) connected to the top of the bottom plate (100), a first connecting plate (502) is rotatably connected to the outer wall of the fixed column (501), a sliding rod (503) is connected to one end of the first connecting plate (502) far away from the fixed column (501), and the shaft sleeve (402) is slidably connected to the outer wall of the sliding rod (503).
4. The fluid distribution system for a seed gene detection kit according to claim 1, wherein the adjusting bracket (700) comprises a guide column (701) connected to the top of the support plate (600), a lead screw (702), and a mounting plate (703) arranged on the top of the guide column (701), the fixing tray (800) is screwed on the outer wall of the lead screw (702) and is slidably connected with the guide column (701), and one end of the lead screw (702) penetrates through the mounting plate (703) and is connected with a hand wheel (704).
5. The fluid dispensing system for a seed gene detection kit according to claim 1, wherein the supporting plate (600) is provided with a groove (601) matching with the tubular kit, the fixing tray (800) is provided with a through hole (801) matching with the tubular kit, and the groove (601) corresponds to the through hole (801).
6. The fluid distribution system for a gene detection kit according to claim 1, wherein the adjustment fixing member (900) comprises a first fixing ring (901) and a second fixing ring (902), the first fixing ring (901) is disposed on the inner wall of the through hole (801) by a first spring (903), and the second fixing ring (902) is disposed inside the through hole (801) by the adjustment member (904).
7. The fluid distribution system for the seed gene detection kit according to claim 6, wherein the adjusting component (904) comprises a second connecting plate (905), a connecting column (906) and a second spring (907), a cavity is formed in the fixing tray (800), the second connecting plate (905) is slidably connected in the cavity, one end of the connecting column (906) is connected to the outer wall of the second connecting plate (905), the other end of the connecting column is connected with the second fixing ring (902), and the second spring (907) is arranged between the second connecting plate (905) and the inner wall of the fixing tray (800).
8. The fluid distribution system for a seed gene detection kit according to claim 7, wherein the second connection plate (905) is provided with a plurality of sets in cooperation with the through hole (801), the second spring (907) is provided between the outermost set of the second connection plate (905) and the inner wall of the fixed tray (800), and the outer wall of the outermost set of the second connection plate (905) is connected with a pull ring (909) through a connection rod (908).
9. The fluid dispensing system for a gene detection kit according to claim 8, wherein the first fixing ring (901) and the second fixing ring (902) are both made of flexible rubber, and the first fixing ring (901) is engaged with the second fixing ring (902).
10. A liquid preparation process for a gene detection kit is characterized by comprising the following steps:
s1: the height of the fixing tray (800) is adjusted according to the size of the model length of the tubular kit, the fixing tray is adjusted to enable the bottom of the tubular kit to be abutted against the groove (601), and the fixing tray (800) is located at the height of two thirds of the tubular kit;
s2: when adjusting fixed tray (800) height, through rotating hand wheel (704), drive lead screw (702) rather than linking to each other and rotate, through slide bar (503) that sets up, and then when rotating hand wheel (704) and driving lead screw (702) and rotate, then can make fixed tray (800) reciprocate along slide bar (503), thereby make it move to make the bottom of tubulose kit offset with recess (601), and it is located tubulose kit two-thirds department height, thereby be convenient for fix tubulose kit, it is provided with the multiunit through recess (601) and through-hole (801) corresponding cooperation, and then can vibrate simultaneously to the multiunit reagent and mix and shake evenly;
s3: pulling a pull ring (909) to drive a connecting rod (908) and a second connecting plate (905) connected with the pull ring to move, thereby compressing a second spring (907), and simultaneously driving a second fixing ring (902) to move towards the inside of a through hole (801), thereby facilitating the placement of a tubular kit to be vibrated and mixed into the through hole (801), inserting the tubular kit into the through hole (801), loosening the pull ring (909) to drive the second connecting plate (905) to return to an original state under the action of the elastic force of the second spring (907), thereby driving the second fixing ring (902) to move towards the center of the through hole (801), when the tubular kit is propped against, a first spring (903) can bear a certain pressure, thereby enabling the first fixing ring (901) and the second fixing ring (902) to tightly prop against the tubular kit, and further enabling the first spring (903) to be arranged, The second spring (907), the first fixing ring (901) and the second fixing ring (902) can conveniently and quickly position the tubular reagent box;
s4: the distance between the first fixing ring (901) and the second fixing ring (902) can be adjusted through the adjusting and fixing assembly (900), so that tubular kits of different models can be fixed, various tubular kits of different models and sizes can be realized, and the universality of the device is improved;
s5: the driving motor (300) is started to drive the turntable (401) connected with the output end of the driving motor to rotate, and the outer wall of the driving motor is eccentrically provided with the shaft sleeve (402) through the connecting block, and the bottom plate (100) is provided with the fixing column (501), the first connecting plate (502) and the sliding rod (503) which are matched with the bottom plate, so that when the driving motor (300) is started, the shaft sleeve (402) can be driven to swing along the fixing column (501) and can also slide up and down along the sliding rod (503);
s6: when the shaft sleeve (402) swings along the fixing column (501) and slides up and down along the sliding rod (503), the supporting plate (600) and the fixing tray (800) can be driven to swing and move up and down, and then the tubular reagent box on the fixing tray (800) is driven to swing and move up and down, so that a good vibration effect is achieved on the reagent in the tubular reagent box.
CN202210411155.9A 2022-04-19 2022-04-19 Liquid preparation process and liquid preparation system for gene detection kit Active CN114887530B (en)

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