CN114869925A - Ginseng radix Rubri processing method for increasing content of rare saponins in Ginseng radix - Google Patents

Ginseng radix Rubri processing method for increasing content of rare saponins in Ginseng radix Download PDF

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CN114869925A
CN114869925A CN202210464992.8A CN202210464992A CN114869925A CN 114869925 A CN114869925 A CN 114869925A CN 202210464992 A CN202210464992 A CN 202210464992A CN 114869925 A CN114869925 A CN 114869925A
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ginseng
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封亮
贾晓斌
梁士魁
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China Pharmaceutical University
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Abstract

The invention discloses a red ginseng processing method for improving the content of rare saponins in ginseng, which promotes the conversion of ginsenosides by raising the steam temperature, and comprises the following steps of cleaning, drying in the shade, weighing and adding water for steaming, wherein the steaming time is 0.25-3 h, after the steaming is finished, the steamed ginseng is taken out and dried in two stages, namely a first stage: drying at 70 ℃ for 10h, second stage: drying at 50 deg.C for 60-72 h to obtain Ginseng radix Rubri with high content of ginsenoside Rg3, Rk1, and Rg 5. The method is used for steaming fresh ginseng with the same mass in the same batch, and the total amount of the ginsenoside Rg3, Rk1 and Rg5 in the obtained novel red ginseng is respectively 27-45 times, 12-20 times and 35-48 times of that of the traditional red ginseng.

Description

Ginseng radix Rubri processing method for increasing content of rare saponins in Ginseng radix
Technical Field
The invention relates to the technical field of processing of traditional Chinese medicine red ginseng, in particular to a red ginseng processing method for improving the content of rare saponins in ginseng.
Background
Ginseng radix Rubri is dried root and rhizome of Panax ginseng C.A.Mey. of Araliaceae after steaming. During the processing of red ginseng, the original ginsenoside can be degraded under the action of high-temperature steam to generate rare saponins such as ginsenoside Rg3, Rk1 and Rg 5. Researches find that rare saponin components such as ginsenoside Rg3, Rk1, Rg5 and the like show good drug effects in the aspects of cancer resistance, inflammation resistance, aging resistance, nerve protection and the like, and particularly show obvious anticancer activity clinically.
The existing steaming method needs complicated pretreatment or addition of auxiliary materials and catalysts, and can not improve the content of rare saponin in red ginseng on the basis of reducing pretreatment and not adding the auxiliary materials and the catalysts.
Disclosure of Invention
The purpose of the invention is as follows: the invention aims to provide a red ginseng processing method for effectively, quickly and greenly improving the content of rare saponins Rg3, Rk1 and Rg5 in ginseng.
The technical scheme is as follows: the red ginseng processing method for improving the content of rare saponins in ginseng comprises the following steps:
(1) cleaning fresh Ginseng radix to remove silt;
(2) drying cleaned fresh ginseng in the shade;
(3) steaming fresh ginseng, wherein the steaming temperature is 120-300 ℃;
(4) and after the steaming is finished, taking out the steamed ginseng and drying.
Further, in the step (2), the cleaned fresh ginseng is dried in the shade for 2 days indoors, and partial water in the fresh ginseng is removed.
Further, in the step (3), the steaming pressure is 0.18MPa to 8.49 MPa.
Furthermore, in the step (3), the steaming time is 0.25 h-3 h.
Preferably, in the step (3), the steaming temperature is 130-150 ℃.
More preferably, in the step (3), the steaming time is 0.25h, and the steaming temperature is 150 ℃.
Further, in the step (4), the red ginseng is taken out after the steaming is finished, and is dried in two stages at the temperature of 50-70 ℃ for 70-82 h.
Further, in the step (4), the temperature of the first stage of drying is 70 ℃ and the time is 10 hours, and the temperature of the second stage of drying is 50 ℃ and the time is 60-72 hours.
Preferably, the rare saponins include Rg3, Rg5, and Rk 1.
Extracting rare saponin: taking a proper amount of red ginseng, crushing, sieving by a No. 4 sieve, precisely weighing 1.0g of red ginseng powder, transferring to a conical flask with a plug, precisely weighing 50mL of methanol, adding to the conical flask, sealing the plug, carrying out ultrasonic (800W, 40kHz) treatment for 2 times, 60min each time, transferring an extracting solution to a 50mL centrifugal tube, centrifuging at 3000rpm/min for 2min, precisely weighing 25mL of a supernatant, placing in an evaporating dish, drying in a 50 ℃ water bath, dissolving residues by adding methanol, transferring to a 5mL measuring flask, adding methanol to a scale, shaking uniformly, filtering by a 0.22 mu m microporous filter membrane, and taking a subsequent filtrate to obtain a liquid to be measured.
Ultra-high performance liquid chromatography analysis: the content of rare saponins Rg3, Rg5 and Rk1 is determined by adopting ultra-high performance liquid chromatography, and the test conditions are as follows: mobile phase: water (B) -acetonitrile (D) flow rate: 0.4mL/min, column temperature: 30 ℃, sample introduction: 2.0. mu.l column: waters ACQUITY UPLC BEHC18 column (Φ 100X 2.1mm,1.7um, number: 186002352); UPLC condition optimization: and selecting the optimal flow rate, analyzing the regularity of the flow rate influencing the separation degree and the column effect, and obtaining the UPLC chromatographic condition with the flow rate of 0.4ml/min after multiple times of adjustment and optimization.
The invention promotes the conversion of ginsenoside by using high-temperature steam on the premise of ensuring the ginseng yield, obviously improves the content of rare saponin, and particularly optimizes a red ginseng processing method for improving the contents of ginsenoside Rg3, Rg5 and Rk1 by steaming ginseng at the high temperature and high pressure of 120-300 ℃ and researching the influence of steaming temperature on the content of rare saponin and the ginseng yield. The method is adopted to steam the same batch of fresh ginseng with the same quality to obtain the novel red ginseng with the obviously increased content of the rare saponin, meanwhile, the total content of the rare saponin is calculated by combining the content of the rare saponin and the ginseng yield, and the total content of the rare saponin Rg3, Rk1 and Rg5 of the optimal novel red ginseng is respectively 27-45 times, 12-20 times and 35-48 times of that of the traditional red ginseng.
Has the advantages that: compared with the prior art, the invention has the following remarkable advantages:
(1) the process is simple and rapid, and the yield is high: the novel red ginseng with high rare saponin content is obtained by promoting the conversion of the ginsenoside under the conditions of high temperature and high pressure, and the total content of the rare saponin of the novel red ginseng reaches the maximum value by combining the ginseng yield. The invention is improved on the basis of the traditional steaming method, and under the premise of not adding any auxiliary material and catalyst, the steaming temperature is increased to promote the conversion of ginsenoside so as to obtain the novel red ginseng with higher rare saponin content;
(2) the method is efficient, rapid and green: according to the processing method, fresh ginseng with the same mass is steamed, the total amount of the rare saponin is calculated by combining the ginseng extraction rate and the content of the rare saponin, and the total amount of the rare saponin Rg3, Rk1 and Rg5 of the optimal novel red ginseng is respectively 27-45 times, 12-20 times and 35-48 times of that of the traditional red ginseng.
Drawings
FIG. 1 is an ultra high performance liquid detection profile of the standard of example 1;
FIG. 2 is an ultra high performance liquid chromatography detection profile of red ginseng of example 1 steamed at 150 ℃ for 0.25 h;
FIG. 3 is an ultra high performance liquid chromatography detection profile of red ginseng of example 1 steamed at 180 ℃ for 0.25 h;
FIG. 4 is an ultra high performance liquid chromatography detection profile of red ginseng steamed at 200 ℃ for 0.25h in example 1;
FIG. 5 is an ultra high performance liquid chromatography detection profile of red ginseng of example 1 steamed at 250 ℃ for 0.25 h;
FIG. 6 is an ultra high performance liquid detection profile of the standard of example 2;
FIG. 7 is a high performance liquid chromatography detection profile of conventional Red Ginseng of example 2;
FIG. 8 is an ultra high performance liquid chromatography detection profile of red ginseng steamed at 120 ℃ for 3 hours in example 2;
FIG. 9 is an ultra high performance liquid chromatography detection profile of red ginseng steamed at 130 ℃ for 3 hours in example 2;
FIG. 10 is an ultra high performance liquid chromatography detection profile of red ginseng steamed at 140 ℃ for 3 hours in example 2;
FIG. 11 is an ultra high performance liquid chromatography detection profile of red ginseng steamed at 150 ℃ for 3 hours in example 2;
FIG. 12 is an ultra high performance liquid chromatography detection profile of red ginseng steamed at 160 ℃ for 3 hours in example 2;
FIG. 13 is an ultra high performance liquid chromatography detection profile of red ginseng steamed at 170 ℃ for 3 hours in example 2;
FIG. 14 is an ultra high performance liquid detection profile of the standard of example 3;
FIG. 15 is a high performance liquid chromatography detection profile of conventional Red Ginseng of example 3;
FIG. 16 is an ultra high performance liquid chromatography detection profile of red ginseng of example 3 steamed at 120 ℃ for 3 hours;
FIG. 17 is an ultra high performance liquid chromatography detection profile of red ginseng of example 3 steamed at 130 ℃ for 3 hours;
FIG. 18 is an ultra high performance liquid chromatography detection profile of red ginseng of example 3 steamed at 140 ℃ for 3 hours;
FIG. 19 is an ultra high performance liquid chromatography detection profile of red ginseng of example 3 steamed at 150 ℃ for 3 hours;
FIG. 20 is an ultra high performance liquid chromatography detection profile of red ginseng of example 3 steamed at 160 ℃ for 3 hours;
FIG. 21 is an ultra high performance liquid chromatography detection profile of red ginseng of example 3 steamed at 170 ℃ for 3 hours;
FIG. 22 is an ultra high performance liquid detection profile of the standard of example 4;
FIG. 23 is a high performance liquid chromatography detection profile of conventional Red Ginseng of example 4;
FIG. 24 is an ultra high performance liquid chromatography detection profile of red ginseng of example 4 steamed at 120 ℃ for 3 hours;
FIG. 25 is an ultra high performance liquid chromatography detection profile of red ginseng of example 4 steamed at 130 ℃ for 3 hours;
FIG. 26 is an ultra high performance liquid chromatography detection profile of red ginseng of example 4 steamed at 140 ℃ for 3 hours;
FIG. 27 is an ultra high performance liquid chromatography detection profile of red ginseng of example 4 steamed at 150 ℃ for 3 hours;
FIG. 28 is an ultra high performance liquid chromatography detection profile of red ginseng of example 4 steamed at 160 ℃ for 3 hours;
FIG. 29 is an ultra high performance liquid chromatography detection profile of red ginseng of example 4 steamed at 170 ℃ for 3 hours;
FIG. 30 is an ultra high performance liquid detection profile of the standard of example 5;
FIG. 31 is an ultra high performance liquid chromatography detection profile of red ginseng steamed at 150 ℃ for 2 hours in example 5;
FIG. 32 is an ultra high performance liquid chromatography detection profile of red ginseng steamed at 150 ℃ for 2.5 hours in example 5;
FIG. 33 is an ultra high performance liquid detection profile of the standard of example 5;
FIG. 34 is an ultra high performance liquid chromatography detection profile of red ginseng steamed at 150 ℃ for 2 hours in example 5;
FIG. 35 is an ultra high performance liquid chromatography detection profile of red ginseng steamed at 150 ℃ for 2.5 hours in example 5;
FIG. 36 is an ultra high performance liquid detection profile of the standard of example 5;
FIG. 37 is an ultra high performance liquid chromatography detection profile of red ginseng steamed at 150 ℃ for 2 hours in example 5;
FIG. 38 is an ultra high performance liquid chromatography detection profile of red ginseng steamed at 150 ℃ for 2.5 hours in example 5.
Detailed Description
The technical scheme of the invention is further explained by combining the attached drawings.
Example 1 steaming temperature Screen
The embodiment provides a red ginseng processing method for improving the content of rare saponins in ginseng, which comprises the following steps:
(1) cleaning: cleaning commercially available fresh ginseng which is bought in Jilin fusong by using a brush;
(2) drying in the shade: drying cleaned fresh radix Ginseng in the shade for 2 days to remove part of water;
(3) high-temperature steaming: grouping the processed fresh ginseng into groups, wherein each group is 100g, and steaming at 150 ℃, 180 ℃, 200 ℃, 250 ℃ and 300 ℃ for 0.25h to obtain samples 1-5;
(4) drying: and drying the steamed ginseng for 10 hours at 70 ℃ in the first drying stage and 60-72 hours at 50 ℃ in the second stage, weighing the obtained red ginseng sample, and recording data.
In the processing method of the embodiment, fresh ginseng of the same batch and same quality is steamed, rare saponins are extracted from the obtained samples 1-5, and the content of each rare saponin is measured.
Extracting rare saponin: taking a proper amount of red ginseng, crushing, sieving by a No. 4 sieve, precisely weighing 1.0g of red ginseng powder, transferring to a conical flask with a plug, precisely weighing 50mL of methanol, adding to the conical flask, sealing the plug, carrying out ultrasonic (800W, 40kHz) treatment for 2 times, 60min each time, transferring an extracting solution to a 50mL centrifugal tube, centrifuging at 3000rpm/min for 2min, precisely weighing 25mL of a supernatant, placing in an evaporating dish, drying in a 50 ℃ water bath, dissolving residues by adding methanol, transferring to a 5mL measuring flask, adding methanol to a scale, shaking uniformly, filtering by a 0.22 mu m microporous filter membrane, and taking a subsequent filtrate to obtain a liquid to be measured.
Ultra-high performance liquid chromatography analysis: the content of rare saponins Rg3, Rg5 and Rk1 is determined by adopting ultra-high performance liquid chromatography, and the test conditions are as follows: mobile phase: water (B) -acetonitrile (D) flow rate: 0.4mL/min, column temperature: 30 ℃, sample introduction: 2.0. mu.l column: waters ACQUITY UPLC BEHC18 column (Φ 100X 2.1mm,1.7um, number: 186002352); UPLC condition optimization: and selecting the optimal flow rate, analyzing the regularity of the flow rate influencing the separation degree and the column effect, and obtaining the UPLC chromatographic condition with the flow rate of 0.4ml/min after multiple times of adjustment and optimization.
TABLE 1UPLC chromatographic conditions
Figure BDA0003623552180000041
Figure BDA0003623552180000051
The results of the ultra-high performance liquid detection are shown in fig. 1-5, the total amount of the rare saponins is calculated, and the total amount of the rare saponins is calculated by combining the yield and the content of the rare saponins, and steaming temperature screening is carried out.
The ginseng yield and the contents of rare saponins Rg3, Rg5 and Rk1 of the red ginseng obtained by the processing are as follows:
TABLE 2 comparison of rare Saponin content (mg/g) at different steaming temperatures
Figure BDA0003623552180000052
Taking 100g of fresh ginseng as a material basis, calculating the data in the table 2 to obtain the total amount of the rare saponins Rg3, Rg5 and Rk1 of each sample in 100g of fresh ginseng as follows:
TABLE 3 comparison of total rare saponins (mg) in fresh ginseng 100g at different steaming temperatures
Figure BDA0003623552180000053
As a result: by comparing the total amount of rare saponins in five groups of red ginseng, the total amount of rare saponins in red ginseng is increased and then decreased along with the increase of the steaming temperature, and the steaming temperature can be preliminarily determined to be within 200 ℃. The fresh ginseng can be completely carbonized after being steamed at 300 ℃ for 0.25h, only a little residue is obtained, and the high-temperature steaming condition at 300 ℃ can be directly eliminated.
Example 2
In this embodiment, the further screening of the steaming temperature specifically includes the following steps:
(1) cleaning: cleaning commercially available fresh ginseng which is bought in Jilin fusong with a brush;
(2) drying in the shade: drying cleaned fresh radix Ginseng in the shade for 2 days to remove part of water;
(3) high-temperature steaming: grouping the processed fresh ginseng into groups, wherein each group is 100g, and steaming the red ginseng at the temperature of 120 ℃, 130 ℃, 140 ℃, 150 ℃, 160 ℃ and 170 ℃ for 3h to obtain a sample 6-11;
(4) drying: and 6-11 drying the steamed ginseng sample, wherein the first drying stage is drying at 70 ℃ for 10 hours, and the second stage is drying at 50 ℃ for 60-72 hours, then weighing the obtained red ginseng sample, and recording data.
Wherein in the step (4), 100g of the processed fresh ginseng is steamed at 100 ℃ for 3 hours, and the obtained conventional red ginseng is used as comparative example 1.
In the processing method of the embodiment, fresh ginseng of the same batch and same quality is steamed, the obtained samples 6-1 to 11-1 and the comparative example 1 are subjected to ultra-high performance liquid phase detection by adopting the same extraction and test method as in the embodiment 1, the results are shown in fig. 6-13, the total amount of rare saponin in the samples is calculated, and the total amount of rare saponin is calculated by combining the ginseng rate and the content of the rare saponin.
The ginseng yield and the contents of rare saponins Rg3, Rg5 and Rk1 of the red ginseng in the samples 6-1 to 11-1 and the comparative example 1 are as follows:
TABLE 4 comparison of Ginseng radix Rubri yield and rare saponins Rg3, Rg5, Rk1 content (mg/g) in example 2
Figure BDA0003623552180000061
Taking 100g of fresh ginseng as a material basis, calculating the data in the table 4 to obtain the total amount of the rare saponins Rg3, Rg5 and Rk1 of each sample in 100g of fresh ginseng as follows:
TABLE 5 comparison of the yield of each Ginseng radix Rubri in example 2 with the total amount of the rare saponins Rg3, Rg5, Rk1(mg) in 100g fresh Ginseng radix
Figure BDA0003623552180000062
Example 3
In order to obtain more accurate contents of rare saponins Rg3, Rg5, and Rk1, the present example repeats the steps of example 2, wherein the red ginseng processing method, the comparative example processing method, and the test conditions and methods are the same, and the shade-dried fresh ginseng is steamed at 120 ℃, 130 ℃, 140 ℃, 150 ℃, 160 ℃, and 170 ℃ for 3 hours to obtain samples 6-2 to 11-2; the dried fresh ginseng in the shade was steamed at 100 ℃ for 3 hours to obtain comparative example 2.
The results of the ultra-high performance liquid detection are shown in fig. 14-21, the total amount of rare saponins in the sample is calculated, and the total amount of rare saponins is calculated by combining the yield and the content of rare saponins.
The ginseng yield and the contents of rare saponins Rg3, Rg5, and Rk1 of red ginseng in samples 6-2 to 11-2 and comparative example 2 were as follows:
TABLE 6 comparison of Ginseng radix Rubri yield and rare saponins Rg3, Rg5, Rk1(mg/g) content in example 3
Figure BDA0003623552180000071
Taking 100g of fresh ginseng as a material basis, calculating the data in the table 6 to obtain the total amount of the rare saponins Rg3, Rg5 and Rk1 of each sample in 100g of fresh ginseng as follows:
TABLE 7 comparison of the yield of each Ginseng radix Rubri in example 3 with the total amount of the rare saponins Rg3, Rg5, Rk1(mg) in 100g fresh Ginseng radix
Figure BDA0003623552180000072
Example 4
In order to obtain more accurate contents of rare saponins Rg3, Rg5 and Rk1, the present embodiment repeats the steps of embodiment 2 again, wherein the red ginseng processing method, the comparative example processing method, and the test conditions and methods are the same, and the shade-dried fresh ginseng is steamed at 120 ℃, 130 ℃, 140 ℃, 150 ℃, 160 ℃ and 170 ℃ for 3 hours to obtain samples 6-3 to 11-3; the dried fresh ginseng in the shade was steamed at 100 ℃ for 3 hours to obtain comparative example 3.
The results of the ultra-high performance liquid detection are shown in fig. 22-29, the total amount of rare saponins in the sample is calculated, and the total amount of rare saponins is calculated by combining the yield and the content of rare saponins.
The yield and the contents of rare saponins Rg3, Rg5 and Rk1 of the red ginseng in the samples 6-3 to 11-3 and the comparative example 3 are as follows:
TABLE 8 comparison of Ginseng radix Rubri yield and rare saponins Rg3, Rg5, Rk1(mg/g) content in example 4
Figure BDA0003623552180000081
Taking 100g of fresh ginseng as a material basis, calculating the data in the table 8 to obtain the total amount of the rare saponins Rg3, Rg5 and Rk1 of each sample in 100g of fresh ginseng as follows:
TABLE 9 comparison of the yield of each Ginseng radix Rubri in example 4 with the total amount of the rare saponins Rg3, Rg5, Rk1(mg) in 100g fresh Ginseng radix
Figure BDA0003623552180000082
As a result: analysis of the data in examples 2-4 shows that the yield of the novel red ginseng obtained by steaming for 3 hours at different temperatures and the contents of the rare saponins Rg3, Rg5 and Rk1 are different, and by calculation, the total amount of the novel red ginseng rare saponins obtained by steaming 100g of fresh ginseng for 3 hours at 150 ℃ is the highest, and the average total amount is: 252.71 mg.
Example 5 steaming time optimization
The preferred conditions selected by the embodiments 1-4 are that the steaming temperature is 150 ℃ and the time is 3h, the embodiment further optimizes the steaming time, and the red ginseng processing method comprises the following steps:
(1) cleaning: cleaning commercially available fresh ginseng which is bought in Jilin fusong with a brush;
(2) drying in the shade: drying cleaned fresh radix Ginseng in the shade for 2 days to remove part of water;
(3) high-temperature steaming: grouping the processed fresh ginseng into groups, wherein each group is 100g, and steaming at the temperature of 150 ℃ for 2 hours and 2.5 hours respectively to obtain samples 12-1-13-1;
(4) drying: and drying the steamed ginseng for 10 hours at 70 ℃ in the first drying stage and 60-72 hours at 50 ℃ in the second stage, weighing the obtained red ginseng sample, and recording data.
Wherein in the step (4), 100g of the processed fresh ginseng is steamed at 100 ℃ for 3 hours, and the obtained conventional red ginseng is used as comparative example 4.
In the processing method of the embodiment, fresh ginseng of the same batch and same quality is steamed, and the obtained samples 12-1 and 13-1 and the comparative example 4 are subjected to ultra-high performance liquid phase detection by adopting the same extraction and test method as the embodiment 1; in order to obtain more accurate experimental results, the above procedure was repeated once to obtain samples 12-2 and 13-2 and comparative example 5; the above procedure was repeated once more to obtain samples 12-3 and 13-3 and comparative example 6.
The results are shown in fig. 30-38, wherein the total amount of rare saponins is calculated, and the total amount of rare saponins is calculated by combining the ginseng ratio and the content of rare saponins, and the results are shown in the table.
TABLE 10 comparison of the extraction rate of each Ginseng radix Rubri in example 5 with the content of the rare saponins Rg3, Rg5, Rk1
Figure BDA0003623552180000091
Taking 100g of fresh ginseng as a material basis, calculating the data in the table 10 to obtain the total amount of the rare saponins Rg3, Rg5 and Rk1 of each sample in 100g of fresh ginseng as follows:
TABLE 11 comparison of the yield of each Ginseng radix Rubri in example 5 with the total amount of the rare saponins Rg3, Rg5, and Rk1 in 100g fresh Ginseng radix
Figure BDA0003623552180000101
As a result: through further optimization of the steaming time of the novel red ginseng, the total amount of rare saponins in a red ginseng sample obtained by steaming 100g of fresh ginseng at 150 ℃ for 2.5 hours is the highest, and the average total amount is as follows: 255.98 mg; and comparing the groups of the parallel groups, wherein the total amounts of Rg3, Rk1 and Rg5 of the novel red ginseng sample prepared by steaming 100g of fresh ginseng at 150 ℃ for 2.5 hours are respectively 27.1-44.7 times, 11.5-20.3 times and 35.2-48.4 times of that of the traditional red ginseng. The total amount of rare saponin is increased, the steaming time is shortened, and the novel red ginseng can be obtained more efficiently and quickly.

Claims (7)

1. A red ginseng processing method for improving the content of rare saponins in ginseng is characterized by comprising the following steps:
(1) cleaning fresh Ginseng radix to remove silt;
(2) drying cleaned fresh ginseng in the shade;
(3) steaming fresh ginseng, wherein the steaming temperature is 120-300 ℃;
(4) and after the steaming is finished, taking out the steamed ginseng and drying.
2. The method for processing red ginseng having an increased rare saponin content of ginseng according to claim 1, wherein in the step (2), the washed fresh ginseng is dried indoors in the shade for 2 days to remove a part of water from the fresh ginseng.
3. The method for processing red ginseng with increased rare saponin content of ginseng according to claim 1, wherein the steaming pressure in step (3) is 0.18Mpa to 8.49 Mpa.
4. The method for processing red ginseng with increased rare saponin content of ginseng according to claim 1, wherein the steaming time in step (3) is 0.25 to 3 hours.
5. The method for processing red ginseng with increased rare saponin content of ginseng according to claim 1, wherein the red ginseng is taken out after steaming and dried in two stages at 50-70 ℃ for 70-82 hours in step (4).
6. The method for processing red ginseng with increased rare saponin content of ginseng according to claim 5, wherein in the step (4), the temperature of the first stage of drying is 70 ℃ for 10 hours, and the temperature of the second stage of drying is 50 ℃ for 60-72 hours.
7. The method for processing red ginseng with improved rare saponin content according to claim 1, wherein the rare saponins comprise Rg3, Rg5 and Rk 1.
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