CN114748603A - Medicine-food homologous composition for preventing and treating new coronavirus pneumonia variation or compound yang and application - Google Patents
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Abstract
The invention relates to a medicinal and edible composition for preventing and treating new coronavirus pneumonia variation or compound yang and application, and belongs to the technical field of traditional Chinese medicines. The invention provides a medicinal and edible composition for preventing and treating new coronavirus pneumonia variation and yang recovery, wherein the traditional Chinese medicine components jointly play a pharmacological role of high-temperature melting and soaking, so that the new coronavirus in the deep respiratory tract epithelial cells is completely melted out, the internal pressure of a cyst membrane of the new coronavirus is increased, and the body shell is expanded and expanded due to thermal expansion, cracked, broken and apoptotic, so that the aims of treatment and prevention are fulfilled, the treatment of the new coronavirus pneumonia is realized, and the variation and yang recovery of the new coronavirus pneumonia are prevented. Meanwhile, the medicinal and edible composition can be used as a food raw material for preparing various types of foods, does not contain any additive or preservative, is suitable for long-term consumption of people of all ages, and is beneficial to the health of human bodies.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a medicinal and edible composition for preventing and treating new coronavirus pneumonia variation or relapse yang and application thereof.
Background
The novel CoronaVirus pneumonia (CoronaVirus Disease 2019, COVID-19) is called new coronaviridae for short, the world health organization is named as '2019 coronaviridae Disease', the pneumonia caused by 2019 novel CoronaVirus infection is indicated, and the pathogeny of the new coronaviridae is similar to the acute Respiratory Syndrome CoronaVirus (SARS-CoV) and middle east Respiratory Syndrome CoronaVirus (MERS-CoV) in structure and is a novel CoronaVirus (SevereAcute Respiratory Syndrome synovium Coronavir-2, SARS-CoV-2) of the same species. The disease has strong infectivity, and is mainly treated by symptomatic support. The clinical manifestations of the new coronary pneumonia patients mainly include viral pneumonia symptoms such as fever and dyspnea, and have imaging characteristics such as double lung infiltration. However, the new coronary pneumonia patients rarely have symptoms of upper respiratory tract such as rhinorrhea, sneezing, sore throat and the like, and the target cells of SARS-CoV-2 are probably located in the lower respiratory tract. In vitro experiments show that the Remdesivir (Remdesivir) and the chloroquine have treatment effect on SARS-CoV-2 infection, which brings hope for treating the new coronary pneumonia. However, the specific pathogenic mechanism of the new coronary pneumonia is not clear at present, and no specific medicine which is clinically verified is available.
Traditional Chinese medicine is an important component of Chinese medical system, and exogenous epidemic diseases play an important role in the treatment of traditional Chinese medicine. The six meridians syndrome differentiation theory in Shang Han Lun explains the transmission and transformation rule of exogenous cold syndrome from exterior to interior, and introduces prescription to begin the first river of exogenous disease. The theory of epidemic febrile disease is formed in the period from jin Yuan to Ming Qing, the differentiation of the exogenous febrile disease is based on the differentiation of the three-jiao and the differentiation of the wei-defense, qi, ying-nutrient and blood, and the emphasis is on the use of heat-clearing and exterior-releasing herbs, thus further enriching the traditional Chinese medicine diagnosis and treatment system of exogenous diseases. In the prior SARS and H7N9 avian influenza epidemic situation, when pathogens are unknown and vaccines are not successfully developed, the traditional Chinese medicine exerts the advantages of cause-time, cause-place, cause-person treatment, disease combination, syndrome differentiation and treatment and the like, and provides a feasible treatment way for the epidemic situation. However, the new coronavirus COVID-19 has the characteristics of sudden change of illness state, strong infectivity, high mortality, mutation, yang recovery and the like, belongs to the field of cold-dampness (plague) of traditional Chinese medicine, is the so-called difficult treatment, mutation and yang recovery of pneumonia of the new coronavirus, has the basic cause that the virus invades the membrane of crouching in the triple energizer, is difficult to reach the position of the medicine, and is difficult to expel and kill the virus.
Disclosure of Invention
The invention aims to provide a medicinal and edible composition, wherein each traditional Chinese medicine component has the pharmacological action of generating high-temperature melt-soaking, and can melt out new coronavirus deep in the body, so that the internal pressure of a capsule membrane of the new coronavirus is increased, and the capsule membrane is expanded, cracked, broken and apoptotic, thereby realizing the purposes of treating the new coronavirus pneumonia and preventing the new coronavirus pneumonia from mutation or reviving yang.
In order to solve the technical problems, the invention provides the following technical scheme:
the invention provides a medicinal and edible composition, which comprises the following raw materials in parts by weight:
10-25 parts of caulis spatholobi, 10-25 parts of purple perilla, 20-60 parts of radix bupleuri, 30-60 parts of rheum officinale, 20-43 parts of vortexes, 10-30 parts of cinnamon, 10-30 parts of dried ginger, 5-20 parts of asarum, 10-30 parts of ephedra, 10-30 parts of pepper, 5-26 parts of monkshood, 20-42 parts of dark plum, 10-26 parts of schisandra chinensis, 10-40 parts of laurel fruit, 10-25 parts of selfheal, 10-25 parts of trichosanthes root, 10-25 parts of liquorice, 10-25 parts of pinellia ternate, 15-40 parts of radix puerariae, 5-35 parts of immature bitter orange, 1-25 parts of inkfish ink powder, 8-25 parts of radix angelicae, 50-83 parts of semen plantaginis, 20-40 parts of almond, 40-65 parts of gypsum, 10-30 parts of white mulberry root-bark, 10-30 parts of radix scutellariae, 5-25 parts of coptis chinensis, 10-30 parts of semen lepidii, 10-35 parts of rhizoma smilacis glabrae, 10-35 parts of bighead atractylodes rhizome, 10-35 parts of peanut bud, 10-45 parts of peanut bud, 15 parts of radish bud, 15-35 parts of radix codonopsis, 25 parts of radix codonopsis, 15-68 parts of rhizoma dioscoreae, 15-66 parts of rhizoma dioscoreae, 15-30 parts of semen raphani, 15-40 parts of medlar, 15-30 parts of Chinese date, 10-40 parts of loach peptide, 10-40 parts of oyster peptide, 25-65 parts of black sesame oil, 15-40 parts of xylitol and 1-15 parts of salt.
Preferably, the medicinal and edible composition comprises the following raw materials in parts by weight:
13-20 parts of caulis spatholobi, 13-20 parts of purple perilla, 22-55 parts of radix bupleuri, 35-55 parts of rheum officinale, 26-38 parts of vortexes, 18-20 parts of cinnamon, 15-20 parts of dried ginger, 9-15 parts of asarum, 14-20 parts of ephedra, 16-20 parts of hollyhock, 10-20 parts of monkshood, 22-35 parts of dark plum, 13-19 parts of schisandra chinensis, 15-34 parts of laurel, 13-20 parts of selfheal, 13-20 parts of trichosanthes root, 13-20 parts of liquorice, 13-20 parts of pinellia ternate, 20-30 parts of radix puerariae, 10-20 parts of immature bitter orange, 8-15 parts of inkfish ink powder, 12-18 parts of radix angelicae, 59-75 parts of semen plantaginis, 28-36 parts of almond, 48-54 parts of gypsum, 13-20 parts of cortex mori, 13-20 parts of radix scutellariae, 8-15 parts of coptis chinensis, 13-20 parts of semen lepidii, 13-20 parts of rhizoma smilacis glabrae, 12-20 parts of bighead atractylodes rhizome, 20 parts of peanut buds, 20 parts of radish buds, 22 parts of radish 22 parts of radix codonopsis, 38-57 parts of Chinese yams, 41-59 parts of Chinese yams, 28-32 parts of medlar, 18-25 parts of Chinese date, 25-34 parts of loach peptide, 25-36 parts of oyster peptide, 44-57 parts of black sesame oil, 27-35 parts of xylitol and 4-10 parts of salt.
More preferably, the kudzuvine root is a kudzuvine root extract, the dark plum is vinegar-soaked dark plum, the monkshood is a processed monkshood, and the liquorice is honey-fried licorice root.
The invention provides a preparation method of the medicinal and edible composition, which comprises the following steps:
mixing fructus Jujubae, caulis Spatholobi, Perillae herba, bupleuri radix, radix et rhizoma Rhei, cortex Cinnamomi, Zingiberis rhizoma, herba asari, herba Ephedrae, radix Aconiti lateralis Preparata, Prunellae Spica, Trichosanthis radix, Glycyrrhrizae radix, rhizoma Pinelliae, radix Angelicae Dahuricae, semen plantaginis, Gypsum Fibrosum, cortex Mori, Scutellariae radix, Coptidis rhizoma, semen Lepidii, fructus Aurantii Immaturus, rhizoma Smilacis Glabrae, and Atractylodis rhizoma, and extracting with water to obtain a first mixture;
micronizing fructus Zanthoxyli, fructus Schisandrae chinensis, and fructus laurel to obtain a second mixture;
steaming mume fructus, semen Armeniacae amarum, Worm, peanut sprout, radix Raphani, radix Codonopsis, rhizoma Dioscoreae, and fructus Lycii, and grinding to obtain a third mixture;
mixing cuttlefish ink powder, loach peptide, oyster peptide, radix Puerariae, xylitol, and salt to obtain a fourth mixture;
and mixing the first mixture with the heated black sesame oil, uniformly stirring, mixing with the third mixture, continuously heating, adding the fourth mixture, stirring, adding the second mixture, and uniformly mixing to obtain the medicinal and edible composition.
Preferably, the Chinese dates are fried before soaking, and the frying temperature is 50-70 ℃.
Preferably, the ratio of the materials of the water extract to the liquid is 1 g: (7-9) mL; the times of water extraction are 1-3 times, and the time of each water extraction is 1-1.5 h.
Preferably, the pepper is fried before being subjected to superfine grinding, and the particle size of the second mixture after superfine grinding is less than or equal to 74 microns.
Preferably, the temperature of the heated black sesame oil is 40-60 ℃, and the temperature after temperature rise is 70-85 ℃.
The invention also provides application of the medicinal and edible composition in preparing a medicine for preventing and treating the new coronavirus pneumonia variation or the new coronavirus pneumonia.
The invention also provides application of the medicinal and edible composition in food.
The invention provides a medicinal and edible composition, which comprises the following components in part by weight: the dried ginger is matched with the Chinese date to coordinate ying and wei, regulate spleen and stomach to ascend stomach qi, the dried ginger is matched with the Chinese magnoliavine fruit to resolve phlegm and purge fluid, astringe lung and relieve asthma, and the dried ginger is matched with the Chinese goldthread root to relieve thirst, reduce bitter taste and lower yang and harmonize yin; the ephedra herb and the gypsum have the effects of cooling and smoothing the bowels, clearing away the lung-heat and relieving asthma, and the ephedra herb and the almond have the effects of dispersing and descending the lung-heat and relieving cough and asthma; the asarum and the schisandra chinensis can disperse and astringe lung qi, resolve retained fluid and relieve asthma; bupleuri radix, Scutellariae radix, radix bupleuri and Shaoyang have effects of regulating the pivot; the coptis root and the cinnamon are matched to dredge the heart and the kidney, so that water and fire are both compensated; ting Li Zi combined with Zi-Zi purges lung and promotes diuresis, sweet and slow tonifies the middle energizer; the immature bitter orange is matched with the largehead atractylodes rhizome to strengthen the spleen and replenish qi, and eliminate stagnation and remove food retention; pinellia ternata is matched with trichosanthes root, and the pinellia ternata is used for clearing away heat and phlegm and relieving asthma; cortex Mori combined with Scutellariae radix for clearing heat, eliminating phlegm and relieving asthma; the medicines can relieve the urine obstruction caused by coronary pneumonia. The medlar and the Chinese date increase hemoglobin and improve endurance; semen plantaginis can relieve cough, resolve phlegm, dredge qi, and relieve constipation due to pathogenic fire and heat in upper jiao caused by new coronary pneumonia. Glabrous greenbrier rhizome, suberect spatholobus stem, kudzuvine root, dahurian angelica root and common selfheal fruit-spike can remove the accumulated toxin of damp-heat of new coronary pneumonia and penetrate into blood collaterals of various collaterals to cause obstruction, ascend the clear and descend the turbid, and remove stasis to promote tissue regeneration. The selfheal, the scutellaria baicalensis, the coptis chinensis and the trichosanthes root are used together for dredging syncope yin and qi stagnation, eliminating lump and hard mass, eliminating cold and heat and eliminating damp arthralgia, so that the phlegm turbidity of the Xinguan pneumonia can be self-eliminated. The perilla, the asarum, the ephedra and the pricklyash peel can be used together to remove turbid phlegm and damp toxin of the new invasive coronary pneumonia from hair slits and deep into the places where the pharmacology can not reach and the turbid water of the stagnant toxin which can not enter without holes from the lung. Dark plum, bupleurum, schisandra chinensis and almond, which unites the three jiao, the five zang-organs and the six fu-organs of the membrane system, stimulates the semi-exterior and semi-interior, muscle fascia, cell membranes, alveolar membranes, lymphatic tissues and oral and tongue mucosa to secrete water metabolism channels, solves the deficiency of the water metabolism of the shaoyang system and the water metabolism function of the lymphatic tissues, secretes a large amount of fresh water, enables the lymph, muscle fascia and the three jiao water metabolism channels to be unblocked, removes the whole stasis and turbidity of shaoyang, lymph, muscle fascia and three jiao, clears the turbid water in the lung, promotes aging to be unblocked, enables the fresh water to be unblocked, clears the upper jiao to be unblocked, the stomach-qi-yin and the body fluids to be discharged, thereby clearing new coronary pneumonia viruses and achieving the purposes of clearing away the lung and expelling toxins.
The medicinal and edible composition of the invention jointly plays a pharmacological role of high-temperature melting and soaking, and completely melts out the new coronavirus in the deep respiratory epithelial cells, so that the capsule membrane internal pressure of the new coronavirus is increased, and the body shell is expanded, cracked, broken and apoptotic, thereby achieving the purposes of treatment and prevention, realizing the treatment of the new coronavirus pneumonia, and preventing the new coronavirus pneumonia from mutation and yang recovery. Meanwhile, the medicinal and edible composition can be used as a food raw material for preparing various types of foods, does not contain any additive or preservative, is suitable for long-term consumption of people of all ages, and is beneficial to the health of human bodies.
Drawings
Fig. 1 shows the lung CT of a patient before taking the medicinal and edible composition of the invention, wherein A, B, C is the lung CT of three different patients respectively.
Fig. 2 shows the lung CT of a patient after taking the medicinal and edible composition of the invention, wherein A, B, C is the lung CT of three different patients respectively.
Fig. 3 shows the lung change results of patients with convalescent coronary pneumonia after taking the medicinal and edible composition of the invention, wherein A, B respectively represent the lung condition after taking the composition for 3 days, 2 for 6 days, 3 for 9 days, 4 for 12 days and 5 for 15 days.
FIG. 4 is a mechanism diagram of the medicine-food homologous composition of the invention for exerting the function of high-temperature infusion.
FIG. 5 is a virus disruption map of the present invention.
Detailed Description
The invention provides a medicinal and edible composition, which comprises the following raw materials in parts by weight:
10-25 parts of caulis spatholobi, 10-25 parts of purple perilla, 20-60 parts of radix bupleuri, 30-60 parts of rheum officinale, 20-43 parts of vortexes, 10-30 parts of cinnamon, 10-30 parts of dried ginger, 5-20 parts of asarum, 10-30 parts of ephedra, 10-30 parts of pepper, 5-26 parts of monkshood, 20-42 parts of dark plum, 10-26 parts of schisandra chinensis, 10-40 parts of laurel fruit, 10-25 parts of selfheal, 10-25 parts of trichosanthes root, 10-25 parts of liquorice, 10-25 parts of pinellia ternate, 15-40 parts of radix puerariae, 5-35 parts of immature bitter orange, 1-25 parts of inkfish ink powder, 8-25 parts of radix angelicae, 50-83 parts of semen plantaginis, 20-40 parts of almond, 40-65 parts of gypsum, 10-30 parts of white mulberry root-bark, 10-30 parts of radix scutellariae, 5-25 parts of coptis chinensis, 10-30 parts of semen lepidii, 10-35 parts of rhizoma smilacis glabrae, 10-35 parts of bighead atractylodes rhizome, 10-35 parts of peanut bud, 10-45 parts of peanut bud, 15 parts of radish bud, 15-35 parts of radix codonopsis, 25 parts of radix codonopsis, 15-68 parts of rhizoma dioscoreae, 15-66 parts of rhizoma dioscoreae, 15-30 parts of semen raphani, 15-40 parts of medlar, 15-30 parts of Chinese date, 10-40 parts of loach peptide, 10-40 parts of oyster peptide, 25-65 parts of black sesame oil, 15-40 parts of xylitol and 1-15 parts of salt.
In the invention, the medicinal and edible composition preferably comprises the following raw materials in parts by weight: 13-20 parts of caulis spatholobi, 13-20 parts of purple perilla, 22-55 parts of radix bupleuri, 35-55 parts of rheum officinale, 26-38 parts of vortexes, 18-20 parts of cinnamon, 15-20 parts of dried ginger, 9-15 parts of asarum, 14-20 parts of ephedra, 16-20 parts of hollyhock, 10-20 parts of monkshood, 22-35 parts of dark plum, 13-19 parts of schisandra chinensis, 15-34 parts of laurel, 13-20 parts of selfheal, 13-20 parts of trichosanthes root, 13-20 parts of liquorice, 13-20 parts of pinellia ternate, 20-30 parts of radix puerariae, 10-20 parts of immature bitter orange, 8-15 parts of inkfish ink powder, 12-18 parts of radix angelicae, 59-75 parts of semen plantaginis, 28-36 parts of almond, 48-54 parts of gypsum, 13-20 parts of cortex mori, 13-20 parts of radix scutellariae, 8-15 parts of coptis chinensis, 13-20 parts of semen lepidii, 13-20 parts of rhizoma smilacis glabrae, 12-20 parts of bighead atractylodes rhizome, 20 parts of peanut buds, 20 parts of radish buds, 22 parts of radish 22 parts of radix codonopsis, 38-57 parts of Chinese yams, 41-59 parts of Chinese yams, 28-32 parts of medlar, 18-25 parts of Chinese date, 25-34 parts of loach peptide, 25-36 parts of oyster peptide, 44-57 parts of black sesame oil, 27-35 parts of xylitol and 4-10 parts of salt. The medicinal and edible composition disclosed by the invention preferably comprises the following raw materials in parts by weight: 15 parts of caulis spatholobi, 15 parts of purple perilla, 50 parts of radix bupleuri, 50 parts of rheum officinale, 30 parts of vortexes, 15 parts of cinnamon, 15 parts of dried ginger, 10 parts of asarum, 15 parts of ephedra, 15 parts of pepper, 15 parts of monkshood, 30 parts of dark plum fruit, 15 parts of schisandra chinensis, 30 parts of laurel fruit, 15 parts of selfheal, 15 parts of trichosanthes root, 15 parts of liquorice, 15 parts of pinellia ternate, 25 parts of radix puerariae, 15 parts of immature bitter orange, 10 parts of cuttlefish ink powder, 15 parts of radix angelicae, 70 parts of semen plantaginis, 30 parts of almond, 50 parts of gypsum, 15 parts of cortex mori, 15 parts of scutellaria baicalensis, 10 parts of coptis chinensis, 15 parts of semen lepidii, 15 parts of rhizoma smilacis glabrae, 15 parts of bighead atractylodes rhizome, 30 parts of peanut bud, 25 parts of radish, 50 parts of codonopsis pilosula, 50 parts of Chinese yam, 30 parts of medlar, 20 parts of Chinese dates, 30 parts of loach peptide, 30 parts of oyster peptide, 50 parts of black sesame oil, 30 parts of xylitol and 5 parts of salt. In the present invention, the pueraria is preferably an extract of pueraria, and the source of the extract of pueraria is not particularly limited, and any commercially available product that is conventional in the art may be used. The smoked plum is preferably smoked plum with vinegar, the monkshood is preferably processed monkshood, and the liquorice is preferably prepared liquorice. The specific processing method of the dark plum is not limited, and the dark plum is processed correspondingly according to the conventional method in the field.
In the invention, the pharmacological effects of the components in the medicinal and edible composition are as follows:
caulis spatholobi: bitter, sweet and warm in property, entering liver and kidney meridians. Promoting blood circulation to regulate menstruation, relaxing muscles and tendons, tonifying blood, removing blood stasis, promoting blood circulation, promoting the circulation of qi, and treating arthralgia due to wind-blood. Can reduce fibrinogen, increase fibrin cleavage products, and has strong effect of inhibiting Hlv-RT activity due to polyamide column chromatography component of caulis Spatholobi water extract. When the concentration is 21. mu.g/mL, the activity of HIV-RT can be completely inhibited.
Purple perilla: pungent and warm in property, they enter lung and spleen meridians. Relieving exterior syndrome, expelling pathogenic factors, removing stagnation, removing filth, eliminating turbid pathogen, treating epidemic warm disease, pathogenic factors sinking to shaoyang, qi stagnation and qi stagnation, channels and collaterals stagnation, liver qi stagnation, chest distress, emesis, cough and asthma, and phlegm coagulation. Pungent and warm herbs can disperse and warm herbs to treat depression, chest obstruction, phlegm-qi stagnation, cough with dyspnea and cough with lingering sound, which can cause the invasion of new and old qi and release pathogenic qi.
Bupleurum root: pungent, bitter and slightly cold in property, entering liver, gallbladder and lung meridians. Disperse and defervesce, soothe liver and relieve depression, lift yang qi, disperse shaoyang semi-exterior and semi-interior, and relieve shaoyang, soothe liver and relieve depression, soothe liver and gallbladder stagnation, relieve blood chamber stagnation, phlegm heat, heat toxin stagnation, phlegm-damp obstruction, fire toxin stagnation, enter shaoyang and jueyin channels leading drugs, remove pathogenic qi in viscera, push old to cause new, stimulate lymph fluid metabolism and cell wall water metabolism.
Rhubarb: bitter and cold in flavor, entering spleen, large intestine, liver and pericardium meridian. Purging the pathogenic accumulation, clearing heat and purging fire, cooling blood and removing toxicity, removing blood stasis and dredging channels, promoting diuresis and removing jaundice, cleaning up the accumulated food in the intestines and stomach, treating the accumulated food of damp-heat in the intestines and stomach, excessive phlegm and saliva, and exuberant toxic heat, and promoting the aging to cause novelty.
And (3) the worm: sweet in nature, contains mature stem cells, can repair injured tissues and has strong organ regeneration capacity.
Cinnamon: pungent and sweet in property, large heat, entering kidney, spleen, heart and liver meridians. Tonify fire and strengthen yang, induce fire to return to its original, dispel cold to alleviate pain, warm meridians and dredge vessels. Pungent, sweet and hot in property, dispersing cold pathogen externally, warming yang qi internally, warming middle-jiao to dispel cold, treating pathogenic cold directly attacking three yin internally, treating rheumatic arthralgia, warming lower energizer, tonifying deficiency of the gate of life, benefiting fire and eliminating yin, which is the essential herb for treating half exterior and half interior of the gate of life. Removing the cold from the deep and descending the body, making yang and yin self-disappear, pungent and warm-moving, blood-system moving, and warming meridians and promoting blood circulation. The virus invading the semi-surface and semi-inner depth of the lipid membrane antigen can be dissolved and infiltrated out from the lipid membrane antigen through the high temperature of the big heat of the big octyl, thereby realizing the purpose of eliminating the virus.
Dried ginger: pungent and hot in flavor, entering spleen, stomach, kidney, heart and lung meridians. Warming the middle energizer to dispel cold, restoring yang to activate collaterals, warming the lung to resolve retained fluid. Pungent and hot with dryness-heat, dredging heart and tonifying yang, removing viscera, cold and pertinence, sending out all cold, treating meridian obstruction, cold arthralgia and dysentery, regurgitation, depletion of primordial yang, syncope of limbs, and increasing cell function.
Asarum: pungent and warm in flavor, enter heart, lung and kidney meridians. Expelling wind and cold, generating intense heat, expelling wind and removing bone, expressing exterior and entering interior, and being nonporous. Unblocking orifices, warming lung and resolving fluid retention. Pungent and warm natured drugs move away and flee, disperse and remove stasis, ascend to the vertex, clear nine orifices, dissipate wind evil, eliminate dampness and turbidity, clear nasal orifices, disperse and warm and dredge, descend qi and break phlegm, cough and asthma, even if the patient can not lie down, disperse pathogen and eliminate phlegm, clear and drink, activate blood and dredge vessels, asarum, ginger and cinnamon which are used as assistants, can dispel cold of viscera, assist the scutellaria, relieve various stagnant heat, and asarum which has the most intense fragrance, is good at expelling stagnation, ascends to the top of the face, clears ears and eyes, reaches bones, ventilates collaterals inside to dredge hundreds of joints, passes through orifices outside to reach the skin directly, and supports beauty.
Herba ephedrae: pungent, slightly bitter and warm in flavor, entering lung and bladder meridians. The pungent flavor can disperse and warm, penetrate out skin pores, and penetrate into phlegm-retention and blood-stasis, so that the ephedra herb can not enter the skin pores in places where pharmacology cannot reach. The lung-qi is released upwards, the bladder is excreted downwards, the water passage is regulated, the diuresis is induced to reduce swelling, the temperature is moderate to disperse and dredge stagnation, the pathogenic factors enter the interior and exterior, the lung depression is relieved, although the exterior is relieved, and the pathogenic factors are discharged. The warm diseases are not relieved by the action of dispersing and dredging, and all the diseases such as cold pathogen stagnated in the lung, nasal obstruction, hoarseness, heat pathogen asphyxia the lung, turbid nasal discharge, nasosinusitis, watery fluid drinking water staining the lung, superficial and dyspnea with rapid respiration, fire burning the lung, excessive heat in the qi, and dryness-fire blazing in the interior are not clear and descending to lung-jin.
And (3) pepper: pungent and warm in flavor. It enters spleen, stomach and kidney meridians. Warming the middle energizer to relieve pain, warming and dredging the meridian, entering the spleen to remove dampness, warming the middle energizer to remove dampness, relieving cold and arthralgia, entering the lung channel to dispel cold and relieve cough, and sending the kidney channel to receive qi and relieve asthma, mainly to dispel wind and pathogenic qi, strengthen the teeth and improve eyesight.
Processing monkshood: pungent and sweet in flavor, large heat, entering heart, kidney and spleen meridians. Pungent, sweet and hot in property, with strong effect, it is a pure yang-dryness and drastic product, and can strengthen heart yang to dredge vessels, warm spleen yang to dispel cold, and tonify kidney yang to replenish fire. The lost original yang can be recovered, the yang can return to the hectare, the shaoyang triple energizer and the life gate can be reached, the yang in yang can move and stop, the vital herbs in the life gate can enter the cave of the yang and attract fire, and the floating fire can be self-extinguished. Pungent flavor and warm nature, pungent and hot nature, rapid and continuous action of fire, no harm, recovery from collapse.
Dark plum: soaked in vinegar, sour, astringent and neutral in flavor, and enter liver, spleen, lung and large intestine meridians. The dark plum guides the membrane system of the triple-focus five viscera and six fu organs, stimulates the secretion water metabolism channels of the semi-exterior, semi-interior, muscular fascia, lymphatic tissues and oral and tongue mucosae, solves the problems of insufficient water metabolism of the membrane system and shaoyang system and the water metabolism function of lymphocyte tissues, secretes fresh water and removes the metabolites of physical and pathological conditions. To replenish essence and stimulate the appetite, astringe the lung, astringe the intestine, stop vomiting, relieve dyspnea and relieve ascaris. Sour, cold and bitter herbs in the blood cover can heal the over-lying blood, which can erode malignant sores and pterygium, dark plum is sour, astringent, warm, enter lung and collect, enter intestine and collect, enter tendon and bone and soft, enter worm and collect, enter dead muscle, malignant flesh and nevus, penetrate into flesh and remove, dyspnea with fullness, regurgitation and steaming of stomach and bones, and lower and upper adverse rising energy can be treated.
Schisandra chinensis: sour, sweet and warm in flavor, entering lung, heart and kidney meridians. Taiyin in hand and Shaoyin in foot. For the patients who are specially used for tonifying kidney, nourishing five internal organs and generating yin and middle muscles, the kidney stores essence, the essence is strong when the kidney is rich, the true qi returns to the original, the red-rooted salvia is warmed, the rice is rotten, the grains are steamed to change the essence into tiny, the essence is generated by self, the essence generates yin and grows, the energy production of an energy storage (cell energy bank) is enhanced, the generation of nitric oxide is activated, and the essential drug for treating asthma and cough is obtained.
Laurel seed: pungent and warm taste, expelling pathogenic wind and dampness, removing toxic substances, killing parasite, and can be used for treating rheumatalgia, globefish poisoning, scabies, and ear sore, reducing blood sugar and blood lipid, preventing corrosion, and inhibiting HIV.
Spica Prunellae, bitter, pungent and cold in flavor, enters liver and gallbladder meridians. Enter the channels of foot jueyin and shaoyang. Pungent flavor can dissipate nodulation, bitter and cold property can purge heat, nourish blood vessel of jueyin, and deficiency syndrome can depend on Huzhang. Specially for phlegm nodule and sore in mice, it is good at clearing heart-qi, can dispel fire in head and eyes, and can reduce the fullness and distension of chest and diaphragm, and treats obstruction of lung-qi as pathogen, which can cause obstruction of clearing and descending, while phlegm is not dispersed between chest and diaphragm, and has the functions of removing stasis and swelling, eliminating cold and heat, dispelling damp arthralgia, and dredging jueyin qi stagnation. The whole herb contains acidic polysaccharide-Prunellae Spica polysaccharide with anti-Human Immunodeficiency Virus (HIV) for inhibiting HIV, and Prunellae Spica saponin has obvious anti-HIV effect. Ursolic acid and its derivatives contained in Prunellae Spica have significant cytotoxic effect on cells P388 and L1210.
Trichosanthis radix, sweet in flavor, slightly bitter and cold in flavor, enters lung and stomach meridians. Clearing heat and purging fire, promoting fluid production to quench thirst, detumescence and expelling pus, removing stagnated heat of five internal organs, descending and isolating heat phlegm, moistening polydipsia in heart, removing intermittent and rapid heat, treating carbuncle and ulcer, removing toxic substance and expelling pus, and can be used for treating phlegm turbidity obstruction in chest, phlegm heat obstruction in lung, cough, chest distress, gasp, dyspnea, cleaning stagnated heat and dirt in chest, and treating heat toxin obstruction, leading phlegm turbidity to descend, relieving cough, eliminating phlegm and relieving asthma. Has immunostimulating effect: the radix trichosanthis has the effect of promoting the formation and the differentiation of spleen immune cells, can increase the medulla alba component of the spleen of a mouse, enlarge the germinal center, widen the margin, and obviously increase the number of 1gM, B lymphocytes and 1gG plasma cells; the macrophage distribution area is enlarged, and the immune globulin IgM is obviously increased after the mice are fed with the trichosanthes root for 7 days. Can enhance immunity. Trichosanthin (TCS) has the functions of enhancing erythrocyte immunity, and increasing erythrocyte C3b receptor and SOD activity level. Enhance PMN phagocytosis of mice. The trichosanthes polysaccharide has obvious proliferation promoting and activating effects on human peripheral blood mononuclear cells, can up-regulate the content of T lymphocyte sub-groups CD3+, CD4+ and CD8+ T cells to different degrees, and can induce high-level secretion of human peripheral blood mononuclear cells to generate TNF-q and IL-6 so as to enhance the immunity of the organism. TCS can inhibit replication and proliferation of HIV in infected immune cells, and reduce the number of live cells infected by virus in immune cells. TCS rapidly deprives infected T cells of the viral active membrane protein gP120, or of the viral central protein P24, within infected monocytes/macrophages. The effective inhibitory concentration of trichosanthin is 0.05-10 mug/mL.
And (3) liquorice moxibustion: sweet in flavor, neutral in nature, and entering heart, lung, spleen and stomach meridians. Tonify spleen and qi, clear heat and remove toxicity, dispel phlegm and stop cough, relieve spasm and pain, and harmonize the drugs. Tonifying primordial qi of the three zang-jiao, governing pathogenic cold and heat in the five zang-organs and six fu-organs, strengthening tendons and bones, strengthening muscles, strengthening the strength, swelling and swelling due to jin-cang, and removing toxicity. Sun Simiao cloud: some Chinese monkshood, croton toxin and licorice root enter abdomen to determine. Glycyrrhizic acid can promote production of IL-2, lFN-r, and inhibit production of IL-4 and IL 10. Monoammonium glycyrrhizinate increases IL-2 production and IL-2R expression. Promoting IL-2 stimulates natural cell growth and enhances cell activity. Glycyrrhizic acid inhibits the lysosome pathway, thereby preventing the formation of membrane attack complexes. Glycyrrhizic acid can inhibit replication of HIV, and has effects of inducing interferon to enhance activity of natural killer cells. Glycyrrhizic acid can inhibit virus DNA replication to produce antiviral effect, and can interfere EB virus penetration into cell to block further replication cycle.
Pinellia ternata: pungent and warm in flavor, enter spleen, stomach and lung meridians. Check adverse rise of qi and arrest vomiting, relieve stuffiness and dissipate nodulation. Pungent and warm natured herbs are the essential herbs for damp-phlegm and cold-phlegm, drying dampness and resolving phlegm. Pungent and pungent with the actions of dissipating nodulation, eliminating phlegm and saliva, stimulating appetite, invigorating spleen, relieving vomiting, removing phlegm fullness in chest, descending lung qi, treating cold phlegm and cough due to cold-type cold-retained fluid, regulating stomach qi, removing stomach cold, and eating, the spleen has no dampness and no phlegm, so the spleen is the source of phlegm generation, and the lung is the device for storing phlegm. The saliva is smooth and moist, and the pungent and warm can disperse and moisten. Therefore, it can remove dampness to relieve constipation, induce resuscitation to drain urine, and stimulate the toxic pathogen in the exterior and interior of the gastrointestinal mucosa, so that the pathological products will be discharged with the feces and pathogenic qi will be discharged.
Kudzu root: pungent, sweet and cool in flavor, entering spleen, stomach and lung channels, releasing muscles and allaying fever, promoting the production of body fluid to relieve cough, clearing and activating the channels and collaterals, pungent and sweet in flavor and cool in nature, pungent can be dispersed thoroughly, and cool in nature and cold in nature. The essential herbs for ascending the clear and descending the turbid and resolving heat pathogen of yang-yin-yang-heat-syndrome. Opening the striae and striae, relieving fever and causing epidemic diseases, and clearing heat pathogen as the key herb for treating yang-open syndrome.
Immature bitter orange: bitter, pungent, sour and slightly cold. It enters spleen, stomach and large intestine meridians. Break qi and relieve stagnation, resolve phlegm and relieve stuffiness, activate pungent and move bitter and descend, enter spleen, stomach and large intestine with strong actions, and treat gastrointestinal stagnation syndrome by breaking qi and relieving stuffiness, relieving stagnation and removing stagnation. Breaking gas and removing fullness. Remove cold and heat accumulation, remove phlegm nodule in chest and hypochondrium, stop water, break fruit and eliminate distention. It can wash the wall and fall down the wall to discharge phlegm.
Ink powder of cuttlefish: mainly treats blood prick and heartache, can obviously improve the level of interferon-V (IFN-V), enhances the killing activity of NK cells, and fully activates the activation effect of mononuclear-macrophage on the cell activity of Lymphokine Activated Killer (LAK). Promoting bone marrow hematopoietic stem cells, inducing to generate a plurality of cell factors, promoting the proliferation of hematopoietic stem cell granulo-monospecific progenitor cells, having obvious effect on a plurality of hemorrhages of gynecology, surgery, internal medicine and the like, and having good effect on the hemorrhages caused by uterine hemorrhage, pulmonary tuberculosis hemoptysis, hematuria, lung cancer hemoptysis, digestive tract ulcer, inflammation and the like.
Radix angelicae: pungent and warm in flavor, enter stomach, large intestine and lung meridians. Relieving exterior syndrome and dispelling cold, dispelling pathogenic wind and relieving pain, ventilating lung and dredging orifice, eliminating dampness and stopping leukorrhagia, relieving swelling and expelling pus, with strong fragrance, pungent and warm nature and dispersing, entering hand-foot yangming, foot taiyin, qi and blood systems, pungent and ascending and dispersing, warming and smoothing qi movement, harmonizing intestines and stomach, ascending head and eyes, and descending and supporting intestines and stomach, reaching limbs in the middle and passing through skin to hair orifices, and benefiting pathogenic qi.
Plantain seed: sweet in flavor and slightly cold in nature, entering liver, kidney, lung and small intestine meridians. Clearing lung-heat and eliminating phlegm, clearing heat from the upper-jiao, opening the middle-jiao and smoothing flow of qi and blood, and promoting defecation,
almond: bitter in taste, slightly warm, entering lung and large intestine meridians. Bitter taste and descending flavor, relieving cough and dyspnea, breaking the congestion and descending adverse flow of qi.
Gypsum: pungent, sweet and cold in flavor, entering lung and stomach meridians. The Taiyin channel of hand, the shaoyang channel and the Yangming channel of foot. Pungent and dispersing and expelling pathogenic heat, expelling pathogenic heat into the lung, treating dyspnea with rapid respiration and dyspnea, high fever, unconsciousness and mania.
White mulberry root-bark: sweet in flavor and cold in nature, it enters lung meridian. Purge lung, relieve dyspnea, induce diuresis to alleviate edema. The main indications are cough with dyspnea, heat phlegm, saliva and blood, which are caused by stagnation of excess pathogens, obstructed lung orifices, residual lung purging, and not mulberry bark. Purging latent fire in the lung can correct qi and eliminate pathogenic factors, so do correction. Cortex Mori contains flavonoids, sanguinarine, cyclomori, morin, leuconostin, cyclomori, etc.; coumarin compounds, 5, 7-hydroxycoumarin, umbelliferone, scopoletin, and scopoletin (6-methoxy-7 hydroxy-coumarin); polysaccharides, mucin, chitin of mulberry polysaccharide, and chitosan; also contains butanol, morin, mulberry bark furan, sitosterol, tannin, volatile oil and the like, and has good effect of resisting various viruses.
Scutellaria baicalensis: the bitter and cold flavor enters lung, gallbladder, spleen, large and small intestine meridians. Clear heat and dry dampness, purge fire and remove toxicity, stop bleeding, prevent abortion. Can be used for treating chest distress, nausea, damp-heat, dysentery, jaundice, cough due to lung heat, hyperpyrexia, polydipsia, hematemesis, carbuncle, swelling, sore, and threatened abortion.
Coptis chinensis: bitter in property and cold in nature, entering heart, liver, stomach and large intestine meridians. Clear heat and dry dampness, purge fire and remove toxicity. Enter heart and uterus collaterals, purge heart fire, remove damp-heat in middle energizer, treat sores, rheumatism and red eye outbreak, and stop blood in the middle. Herbs that can remove dampness must increase heat, while herbs that can remove heat must not remove dampness. But Huang Lian can dry dampness with its bitter taste and clear heat with its cold property. Coptis root, rhizoma Coptidis, being bitter and cold in nature, is bitter and dampness-drying, cold prevailing and heat, can lower all the remaining damp-fire, while the heat of heart, spleen, liver and kidney, the fire of gallbladder, stomach, large intestine and small intestine, no incurable, eye diseases due to wind-fire in upper and middle meridians, vomiting of liver and stomach, and abdominal pain and stagnation all have the effects of drying dampness and clearing heat, clearing and cleaning blood heat, vomiting, bleeding and bloody urine, bloody stool and stranguria with turbid urine and erysipelas of pain intestine. The berberine can inhibit the adhesion of polymorphonuclear leukocytes and vascular endothelial cells induced by IL-1 or TNF and the expression of adhesion molecules ICAM-1 and CD18, the berberine has obvious inhibition effect on the expression of T cell early activation antigen CD69 and intermediate activation antigen CD25, and the berberine has influence on PKC or downstream signal pathways thereof and can inhibit the adhesion between lymphocytes and vascular endothelial cells by down-regulating the expression of adhesion molecules. Thus affecting lymphocyte recirculation. Proves that the berberine has obvious effect on the activation and proliferation of T cells.
Semen lepidii: pungent, bitter and cold in nature, it enters lung and bladder meridians. Purge lung, relieve dyspnea, induce diuresis to alleviate edema. Relieve the obstruction of lung-qi to regulate water passage. It is the right-handed herb for the Taiyin channel, and also enters the yang-Ming channel of hand and the yang-Tai channel of foot. Bitter and descending with pungent flavor and cold and cool property, it can break stagnation and resolve stagnation, check adverse flow of qi and stop dyspnea. Governing scar and mass accumulation and stagnation of qi, food cold and heat, breaking hardness and eliminating evil, and dredging water passages.
Glabrous greenbrier rhizome: sweet, bland and neutral in flavor, entering liver and stomach meridians. Remove toxicity, remove dampness, and smooth joints. As the essential herb for treating syphilis, it can remove dampness and heat, enter meridians, and remove damp-heat accumulated toxicity. Deep into the collaterals, arthralgia, even putridity, ascending of toxic fire, sore throat, all kinds of malignant diseases. Rhizoma Smilacis Glabrae contains astilbin, isoengelhardoside, smilacin, quercetin, dioscin, daucosterol, alkaloid, sterol, organic acid, volatile oil, starch, tannin, etc. Has good anti-inflammatory and anti-human megacytotoxicity effects.
White atractylodes rhizome: bitter, sweet and warm in taste, entering spleen and stomach meridians. Invigorating spleen and qi, and treating new coronary pneumonia, diarrhea, excessive phlegm and fluid retention, vertigo, palpitation, fullness in chest and hypochondrium, cough, and short breath. It is indicated for arthralgia due to wind-cold-dampness, with Bai Zhu being bitter and warm in property, strengthening spleen and drying dampness, and can be indicated for arthralgia due to wind-warm wind, strengthening spleen to assist the transportation of intestines and to restore the function of intestines descending, so it is also indicated for constipation. When the body is too strong, it can expel dampness, so it is also used for phlegm-fluid retention, swelling and damp arthralgia. When the soil is too strong, the clear qi rises well, the essence rises upwards, the turbid qi descends well, and the dregs are transported downwards, which is the essential herb for the acquired resources. Effects on the immune system: improving TH/TS ratio, correcting T cell subgroup distribution disorder state, remarkably improving low IL-2 level, increasing IL-2R expression on T lymphocyte surface, scavenging free radicals, and improving erythrocyte SOD activity.
Loach peptide: induce diuresis to treat stranguria, remove toxicity and relieve swelling, and resist bacteria and diminish inflammation. The loach polysaccharide can obviously enhance the proliferation capacity of spleen lymphocytes of mice induced by ConA and increase the content of serum hemolysin of the mice.
Oyster peptide: not only contains the original nutrients of the oyster such as vitamins, trace elements, taurine and the like, but also the proportion of micromolecule oligopeptide with the relative molecular weight of less than 1000Dalton is more than 80 percent. The main component of oyster peptide is oyster, commonly called oyster and oyster, according to the record of compendium of materia Medica: oyster can cure deficiency, strengthen yang, detoxify, replenish qi and blood of men and women, make skin tender and prevent aging, and the main component glycogen can quickly replenish and restore physical strength and improve the immunity of organisms. Meanwhile, the traditional Chinese medicine composition has the functions of improving the testosterone level of male serum, regulating blood fat, inhibiting platelet aggregation, improving hyperglycemia symptoms, promoting metabolism and the like, and also has certain effects of resisting cancer and preventing cancer cell diffusion.
Chinese yam: sweet in flavor and neutral in nature, it enters spleen, lung and kidney meridians. Tonify kidney qi, strengthen spleen and stomach, stop diarrhea, resolve phlegm and saliva. The Chinese yam polysaccharide (RDPS-I) can improve the T lymphocyte proliferation capacity, NK cell and serum hemolysin activity and serum lgG content to different degrees, can also enhance the phagocytic capacity of macrophages, has a non-specific immune function, and can also enhance specific cellular immunity and humoral immunity functions, the Chinese yam polysaccharide RDPS-I can obviously enhance the T lymphocyte proliferation capacity and NK cell activity of tumor-bearing mice, the IL-2 production capacity of spleen cells of the mice and TNF-alpha production of abdominal cavity macrophages.
Medlar: sweet in flavor, neutral in nature, entering liver, kidney and lung meridians. Enter the foot shaoyin and foot jueyin meridians. Nourishing liver, replenishing kidney essence, moistening lung. The lycium barbarum polysaccharide can obviously enhance the NO induction quantity of static giant cells in abdominal cavities of mice and macrophages activated by sodium Thioglycolate (TC) and the activities of intracellular lysozyme and SOD, the lycium barbarum polysaccharide exceeds 50mg/(bg/d) dose, and can obviously enhance the phagocytic index of the giant cells by gastric lavage, the activity of serum hemolysin of experimental mice is obviously enhanced, the polysaccharide can obviously increase the weight of thymus and spleen of the mice, the gastric lavage effect is the best at 10mg/Kg, and the activity of NK cells of normal mice and mice treated by cyclophosphamide (Cy) can be enhanced. The medlar can activate macrophages to generate IL-1, activate T lymphocytes to generate IL-2, activate NK cells, increase the proliferation of the T lymphocytes and the expression of CD3+, CD4+ and CD8+, can proliferate the lymphocytes after the synergistic effect of medlar polysaccharide and Phytohemagglutinin (PHA), wherein the PHA is a T cell non-specific mitogen and can be combined with a CD/TCR complex on the surface of the T cells to cause the phosphorylation of cell surface molecules such as CD3+, CD4+, CD8+ and LAF-1, and the PKC pathway is activated to cause the cell activation and promote the lymphocytes to enter a proliferation cycle to proliferate. The medlar can obviously enhance T lymphocyte proliferation reaction stimulated by ConA, has obvious enhancement effect on B cell immune function and promotes splenocytes to generate IL-2 level. Lycium Barbarum Polysaccharides (LBPs) can promote the differentiation of Dendritic Cells (DC) cultured in vitro, mature to improve the level of surface expression MHC-II, CD83, CD86(B7-2) and CDIla (LFA-I), promote the secretion of IL-12P40 by DC, enhance the proliferation capacity of T cells, convert T lymphocytes into killer T cells and improve the killing activity of the T cells.
Codonopsis pilosula: sweet in property, neutral in nature, and entering spleen and lung meridians. To invigorate the spleen, benefit the lung, nourish blood and promote the production of body fluid. It can be used to replace human beings to take part in Poria, Atractylodis rhizoma and radix Glycyrrhizae Preparata for strengthening spleen qi, producing stomach qi and dying without stomach qi. Can be used for substituting for radix astragali, fructus Schisandrae chinensis, radix Asteris, and cortex Mori, and has effects of invigorating lung, invigorating qi, relieving cough and asthma, especially for invigorating spleen without dryness; nourishing stomach yin without dampness; moistening lung without causing coldness and coldness; nourish blood without being greasy; inspiring the clear yang and vibrating the middle qi without the disadvantage of dryness. Choline acetyltransferase (CHAT) recombinant proteins produce increased amounts of ACH. The SOD activity is enhanced, the number of macrophages is obviously increased, the cell volume is increased, the pseudopodia is increased, the phagocytic capacity is enhanced, the activities of DNA, RNA, saccharides, ACP enzyme, ATP enzyme, acid esterase and succinate dehydrogenase in cells are all obviously enhanced, and the functions of lymphocyte transformation and antibody formation and the level of antibody titer can be obviously enhanced for mice in an immune suppression state caused by cyclophosphamide. Has effect of recovering AMAE + LC rate and DTH of mouse with immunosuppression caused by CY. Has effect in increasing interleukin-2 production of spleen lymphocyte of rat with Cyclophosphamide (CY) immunosuppression, and can increase IL-2 growth index. The codonopsis pilosula polysaccharide has strong promotion effect on humoral immunity and cellular immunity, and also has obvious promotion effect on lymphocyte stimulated by the canavalin A.
Chinese date: sweet in flavor and warm in nature, it enters spleen, stomach and heart meridians. Tranquilizing the middle energizer, nourishing the mind, assisting twelve meridians, tonifying yin and yang, qi and blood, body fluids, meridians, muscle and back transport, and bone marrow, regulating the phlegm of deficiency stagnation of the middle energizer. It is good at nourishing yin and yang, qi and blood, body fluids, meridians, jin Shu and all kinds of deficiency. It should not be used for liver and spleen injuries, deficiency of earth and wood, wind and blood consumption. The Chinese date polysaccharide can obviously increase the mouse red blood cell C3b receptor (RBC-C3bR) rosette rate and the red blood cell immune complex (RBC-IC) rosette rate, and can make the Cy-induced reduction of the RBC-C3b rosette rate and the RBC-C rosette rate rise back obviously.
Black sesame oil and peanut sprouts: the natural vitamin E has effects of resisting cell oxidation, nourishing liver and kidney, and replenishing essence and blood, and can be used for treating constipation due to new coronary pneumonia.
Radish: has antiviral effect, and can be used for relieving constipation, and treating asthenia, aversion to cold, fever, headache, nasal obstruction, cough, and excessive phlegm caused by new coronary pneumonia.
Xylitol: the sugar substitute can be directly absorbed without insulin for diabetic patients, and can prevent dental caries.
Salt: the main component is sodium chloride, which is the main electrolyte in extracellular fluid and is an important component for maintaining osmotic pressure, regulating the acid-base balance of the body and regulating food flavor.
In the invention, the medicinal and edible composition takes spatholobus stem, perilla, radix bupleuri, rhubarb, vortexes, cinnamon, dried ginger, asarum, ephedra, pricklyash peel and monkshood as monarch drugs, dark plum fruit, schisandra fruit, laurel fruit, selfheal, trichosanthes root, liquorice, pinellia tuber, kudzuvine root and immature bitter orange as ministerial drugs, inkfish ink powder, angelica dahurica, plantain seed, almond, gypsum, mulberry bark, scutellaria baicalensis, coptis chinensis, semen lepidii, glabrous greenbrier rhizome and bighead atractylodes rhizome as adjuvant drugs, peanut bud, radish, codonopsis pilosula, Chinese yam, medlar, Chinese date, loach peptide, oyster peptide, black sesame oil, xylitol and salt as conductant drugs, the drugs generate pharmacological action of high-temperature melt soaking together through reasonable compatibility relationship, and the drug is stood on the semi-surface semi-interior, deep air passage and air cavity semi-surface semi-interior of cell membrane, air cavity and air cavity semi-surface semi-interior of air cavity composed of a plurality of composite cells of respiratory tract epithelial tissues, namely hair column-shaped epithelial tissues, the new corona virus is melted out from the skin, lining, channels, lymph tissue, the cavity system of the internal organs and the lipid oil film, the hair of the skin striae and the phlegm-retention blood, so that the internal pressure of the new corona cyst membrane virus is increased, the body shell is expanded by heat, cracked, broken and apoptotic, and all the new corona virus is eliminated, thereby preventing the variation and the yang recovery of the new corona virus.
The invention provides a preparation method of the medicinal and edible composition, which comprises the following steps:
mixing fructus Jujubae, caulis Spatholobi, Perillae herba, bupleuri radix, radix et rhizoma Rhei, cortex Cinnamomi, Zingiberis rhizoma, herba asari, herba Ephedrae, radix Aconiti lateralis Preparata, Prunellae Spica, Trichosanthis radix, Glycyrrhrizae radix, rhizoma Pinelliae, radix Angelicae Dahuricae, semen plantaginis, Gypsum Fibrosum, cortex Mori, Scutellariae radix, Coptidis rhizoma, semen Lepidii, fructus Aurantii Immaturus, rhizoma Smilacis Glabrae, and Atractylodis rhizoma, and extracting with water to obtain a first mixture;
micronizing fructus Zanthoxyli, fructus Schisandrae chinensis, and fructus laurel to obtain a second mixture;
steaming mume fructus, semen Armeniacae amarum, Worm, peanut sprout, radix Raphani, radix Codonopsis, rhizoma Dioscoreae, and fructus Lycii, and grinding to obtain a third mixture;
mixing ink powder of cuttlefish, loach peptide, oyster peptide, radix Puerariae, xylitol, and salt to obtain a fourth mixture;
and mixing the first mixture with the heated black sesame oil, stirring uniformly, mixing with the third mixture, continuously heating, adding the fourth mixture, stirring, adding the second mixture, and mixing uniformly to obtain the medicinal and edible composition.
In the invention, the Chinese dates are preferably fried before soaking, and the frying temperature is preferably 50-70 ℃, and more preferably 58-64 ℃. The method and time for frying the Chinese dates are not particularly limited, and the Chinese dates are fried to be brown according to the conventional frying method in the field. In the invention, the ratio of the water to the feed liquid is preferably 1 g: (7-9) mL, more preferably 1 g: 8 mL; the number of the water extractions is preferably 1 to 3, more preferably 2; the time of each water extraction is preferably 1-1.5h, more preferably 1.2-1.3 h. In the present invention, the water extraction preferably comprises filtration, and the first mixture is obtained by mixing the filtered extracts.
In the present invention, the zanthoxylum bungeanum maxim is preferably roasted before being pulverized into superfine powder, and the roasting method is not particularly limited in the present invention, and a conventional roasting method for the zanthoxylum bungeanum maxim in the art may be adopted. In the present invention, the particle size of the second mixture after the micronization is preferably 74 μm or less, more preferably 70 μm or less. The method of steaming and grinding is not particularly limited in the present invention, and a steaming and grinding method which is conventional in the art may be used. In the present invention, the temperature of the heated black sesame oil is preferably 40 to 60 ℃, more preferably 48 to 52 ℃; the temperature after the temperature rise is preferably 70 to 85 ℃, more preferably 80 to 82 ℃.
In the invention, after the second mixture is added, preferably, the mixture is continuously fried and stirred until the hardness of the finished product is proper, so that the medicinal and edible composition can be obtained. The device for frying with hot oil is not particularly limited, and in the specific embodiment of the invention, the device for frying with hot oil is preferably a fully automatic planetary stirring wok.
The invention also provides application of the medicinal and edible composition in preparing a medicine for preventing and treating the new coronavirus pneumonia variation or the new coronavirus pneumonia. The invention does not specially limit the dosage form or the auxiliary materials of the medicine, and the proper auxiliary materials and the preparation process are selected according to the dosage form.
The invention also provides application of the medicinal and edible composition in food. The food is not particularly limited in type, and the medicinal and edible composition can be prepared into various products in the form of paste, sand, sauce and cake as well as soft, tough and tough peptide preferably; or used as stuffing in all products capable of sandwiching stuffing in foods such as cakes, moon cakes, bread, rice dumplings and the like; or used for making ice cream, etc; or processing chocolate and fruit paste and fruit cake. In the present invention, the food is preferably prepared without adding any additives and preservatives.
In the invention, the raw materials, reagents and equipment are known products, and conventional commercial products can be adopted.
In order to further illustrate the present invention, the following embodiments are described in detail, but they should not be construed as limiting the scope of the present invention.
Example 1
1) Mixing 20 parts of Chinese date, 15 parts of suberect spatholobus stem, 15 parts of purple perilla, 50 parts of Chinese thorowax root, 50 parts of rhubarb, 15 parts of cassia bark, 15 parts of dried ginger, 10 parts of manchurian wildginger, 15 parts of ephedra herb, 15 parts of prepared common monkshood daughter root, 15 parts of common selfheal fruit-spike, 15 parts of Mongolian snakegourd root, 15 parts of liquoric root, 15 parts of pinellia tuber, 15 parts of dahurian angelica root, 70 parts of plantain seed, 50 parts of gypsum, 15 parts of white mulberry root-bark, 15 parts of baical skullcap root, 10 parts of golden thread, 15 parts of pepperweed seed, 15 parts of glabrous greenbrier rhizome, 15 parts of immature bitter orange and 15 parts of largehead atractylodes rhizome, adding 8 times of water for soaking, placing into an extraction tank for extraction for 2 times, extracting for 1 hour each time, filtering to remove dregs, and combining the two extracting solutions to obtain a first mixture;
2) parching 15 parts of fructus Zanthoxyli, and micronizing with cleaned and dried 15 parts of fructus Schisandrae chinensis and 30 parts of fructus laurel to obtain a second mixture with particle size of 70 μm;
3) removing cores of 30 parts of vinegar-soaked dark plums, peeling and soaking 30 parts of almonds, then putting the soaked dark plums, 30 parts of turbots, 30 parts of peanut buds, 25 parts of radishes, 50 parts of codonopsis pilosula, 50 parts of Chinese yams and 30 parts of Chinese wolfberries into a pot for steaming, and then grinding the mixture into thick paste to obtain a third mixture;
4) mixing 10 parts of cuttlefish ink powder, 30 parts of loach peptide, 30 parts of oyster peptide, 25 parts of kudzu root extract, 30 parts of xylitol and 5 parts of salt to obtain a fourth mixture;
5) and mixing the first mixture with 50 parts of 50-DEG C black sesame oil, uniformly stirring, mixing with the third mixture, continuously heating to 80 ℃, adding the fourth mixture, continuously stirring and frying, then adding the second mixture, continuously stirring, and uniformly stirring to obtain the medicinal and edible composition.
Example 2
1) Mixing 15 parts of Chinese date, 10 parts of caulis spatholobi, 10 parts of purple perilla, 20 parts of radix bupleuri, 60 parts of rheum officinale, 10 parts of cinnamon, 10 parts of dried ginger, 5 parts of asarum, 10 parts of ephedra, 5 parts of monkshood, 10 parts of selfheal, 10 parts of trichosanthes root, 10 parts of liquorice, 10 parts of pinellia ternate, 8 parts of radix angelicae, 50 parts of semen plantaginis, 40 parts of gypsum, 10 parts of cortex mori radicis, 10 parts of scutellaria baicalensis, 5 parts of coptis chinensis, 10 parts of semen lepidii, 5 parts of immature bitter orange, 10 parts of rhizoma smilacis glabrae and 10 parts of rhizoma atractylodis macrocephalae, adding 7 times of water for soaking, placing into an extraction tank for extraction for 1 time, extracting for 1.5 hours, and filtering to remove dregs of a decoction to obtain a first mixture;
2) frying 10 parts of pricklyash peel to be fragrant, and then carrying out superfine grinding on the fried pricklyash peel, 10 parts of cleaned and dried schisandra chinensis and 10 parts of laurel to obtain a second mixture with the particle size of 74 mu m;
3) removing cores of 20 parts of vinegar-soaked smoked plums, peeling and soaking 20 parts of almonds, putting the soaked plums, 20 parts of the vortexes, 10 parts of peanut buds, 15 parts of radishes, 20 parts of codonopsis pilosula, 25 parts of Chinese yams and 15 parts of Chinese wolfberries into a pot for steaming, and grinding the mixture into thick slurry to obtain a third mixture;
4) mixing 1 part of cuttlefish ink powder, 10 parts of loach peptide, 10 parts of oyster peptide, 15 parts of kudzu root extract, 15 parts of xylitol and 1 part of salt to obtain a fourth mixture;
5) and mixing the first mixture with 25 parts of hot oil of black sesame oil with the temperature of 40 ℃, uniformly stirring, mixing with the third mixture, continuously heating to 70 ℃, adding the fourth mixture, continuously stirring and frying, then adding the second mixture, continuously stirring, and uniformly stirring to obtain the medicinal and edible composition.
Example 3
1) Mixing 30 parts of Chinese date, 25 parts of caulis spatholobi, 25 parts of purple perilla, 60 parts of radix bupleuri, 30 parts of rheum officinale, 30 parts of cinnamon, 30 parts of dried ginger, 20 parts of asarum, 30 parts of ephedra, 26 parts of monkshood, 25 parts of selfheal, 25 parts of trichosanthes root, 25 parts of liquorice, 25 parts of pinellia ternate, 25 parts of radix angelicae, 83 parts of semen plantaginis, 65 parts of gypsum, 30 parts of cortex mori radicis, 30 parts of scutellaria baicalensis, 25 parts of coptis chinensis, 30 parts of semen lepidii, 35 parts of immature bitter orange, 35 parts of rhizoma smilacis glabrae and 35 parts of bighead atractylodes rhizome, adding 9 times of water for soaking, placing into an extraction tank for extraction for 3 times, extracting for 1 hour each time, filtering to remove dregs of dregs, and combining the two extracting solutions to obtain a first mixture;
2) parching 30 parts of fructus Zanthoxyli, and micronizing with 26 parts of cleaned and dried fructus Schisandrae chinensis and 40 parts of laurel to obtain a second mixture with particle size of 74 μm;
3) removing cores of 42 parts of vinegar-soaked dark plums, peeling and soaking 40 parts of almonds, then putting the soaked dark plums, 43 parts of worms, 45 parts of peanut buds, 35 parts of radishes, 68 parts of codonopsis pilosula, 66 parts of Chinese yams and 40 parts of Chinese wolfberries into a pot for steaming, and then grinding the steamed plums into thick paste to obtain a third mixture;
4) mixing 25 parts of cuttlefish ink powder, 40 parts of loach peptide, 40 parts of oyster peptide, 40 parts of kudzu root extract, 40 parts of xylitol and 15 parts of salt to obtain a fourth mixture;
5) and mixing the first mixture with 65 parts of hot oil of 60 ℃ black sesame oil, uniformly stirring, mixing with the third mixture, continuously heating to 85 ℃, adding the fourth mixture, continuously stirring and frying, then adding the second mixture, continuously stirring, and uniformly stirring to obtain the medicinal and edible composition.
Example 4
1. Test object
In a hospital, 3 light cases of patients with new coronary pneumonia were collected, and clinically manifested by fever, pulmonary dispersion, asthenia, cough, chest distress, short breath, poor body, positive nucleic acid detection, abnormal pulmonary ventilation and movement, and pulmonary CT with frosted glass (S spike protein), as shown in FIG. 1.
2. Method of treatment
The medicine and food homologous composition disclosed in the embodiment 1 of the invention is taken for treatment in all the cases, wherein the composition disclosed in the embodiment 1 of the invention is orally taken 3 times a day, 1 time each in the morning, noon and evening, 18g each time, and 7 days continuously.
3. Results of the experiment
The pulmonary CT results for 3 patients are shown in fig. 2. The results show that: the worn vitreous and stringy pulmonary images of all patients become light, the fibrotic absorption and the vital capacity function are improved. Meanwhile, all patients breathe smoothly, cough and expectoration symptoms disappear, and the nucleic acid result shows negative.
Example 5
1. Test object
30 patients who have negative detection of the new coronary pneumonia nucleic acid and have sequelae in the convalescence stage are collected in a hospital, wherein all the sequelae have pulmonary CT before the experiment, and the result shows that: the lung is dispersed, and the lung CT still has the symptoms of frostbite, shortness of breath, cough, hypodynamia, unsmooth breathing after exercise and the like.
2. Method of treatment
The experimental subjects are all treated by adopting the medicine-food homologous composition disclosed in the embodiment 1 of the invention, wherein the composition disclosed in the embodiment 1 of the invention is taken 2 times a day, 1 time in the morning and evening respectively, 18g of the composition is taken each time, and the composition is chewed and taken for 15 days continuously.
3. Results of the experiment
After 30 cases take the medicinal and edible composition disclosed in embodiment 1 of the invention, the relief of symptoms such as shortness of breath, cough, fatigue, and poor breathing after exercise is observed, and pulmonary CT is performed at the same time, wherein 2 cases of results are shown in fig. 3.
It can be seen that after the composition of example 1 of the present invention was administered, the vitreous lung shadow became shallow in all cases, the fibrosis was absorbed earlier, the lung breathes smoothly, the cough symptom disappeared, and the sputum disappeared, and all the new coronavirus could be effectively removed, and the variation and the revitalization of the new coronavirus could be prevented.
Comprehensive analysis shows that the spicy and nutritional energy medicinal components of caulis spatholobi, chaihu, radix bupleuri, rheum officinale, smoked plum, volutidea, schisandra chinensis, pinellia ternate, radix puerariae, immature bitter orange, cuttlefish black powder, angelica dahurica, plantain seed, almond, gypsum, cortex mori radicis, scutellaria baicalensis, coptis chinensis, semen lepidii, rhizoma smilacis glabrae, bighead atractylodes rhizome, loach peptide, oyster peptide, peanut sprouts, radishes, codonopsis pilosula, Chinese yam, medlar, Chinese date, black sesame oil and xylitol are utilized to store nutrition for cells, energy is continuously provided, and the warm-assisting six-tiger medicine 'cinnamon, dried ginger, asarum, ephedra, pepper and monkshood' plays a powerful warming role to enable the cells to generate huge heat energy, as shown in figure 4.
According to the melting points and boiling points of the medicines, the traditional Chinese medicine squat the skin, the inside and the outside of the skin, the cavity pipeline, the channels, the collaterals, the lymph tissue, the lipid oil films of the internal organs and the interstitial hair of the viscera, all new crown viruses deep in phlegm retention and blood stasis, deep air passages, the half interior of the pulmonary alveoli and the half interior of the pulmonary alveoli can be dissolved out by reasonably matching the medicines, and the new crown viruses which penetrate into the skin, the inside and the outside of the skin, the cavity pipeline, the channels, the collaterals, the lymph tissue, the five viscera and the six bowels can be removed, and the new crown viruses which penetrate into the deep air passages, the half interior of the pulmonary alveoli and the half interior of the pulmonary alveoli can be removed, so that the virus protein membranes can be thermally expanded, internally pressurized and expanded, cracked and apoptotic bodies can be removed no matter how the new crown viruses are changed, as shown in figure 5, thereby completely eliminating the viruses invading the original triple membrane, realizing the treatment of the new crown pneumonia, and simultaneously preventing the change and the relapse of the new crown viruses.
The above description is only an embodiment of the present invention, and not intended to limit the scope of the present invention, and all modifications of equivalent structures and equivalent processes, which are made by the present specification, or directly or indirectly applied to other related technical fields, are included in the scope of the present invention.
Claims (10)
1. A medicinal and edible composition is characterized by comprising the following raw materials in parts by weight:
10-25 parts of caulis spatholobi, 10-25 parts of purple perilla, 20-60 parts of radix bupleuri, 30-60 parts of rheum officinale, 20-43 parts of vortexes, 10-30 parts of cinnamon, 10-30 parts of dried ginger, 5-20 parts of asarum, 10-30 parts of ephedra, 10-30 parts of pepper, 5-26 parts of monkshood, 20-42 parts of dark plum, 10-26 parts of schisandra chinensis, 10-40 parts of laurel fruit, 10-25 parts of selfheal, 10-25 parts of trichosanthes root, 10-25 parts of liquorice, 10-25 parts of pinellia ternate, 15-40 parts of radix puerariae, 5-35 parts of immature bitter orange, 1-25 parts of inkfish ink powder, 8-25 parts of radix angelicae, 50-83 parts of semen plantaginis, 20-40 parts of almond, 40-65 parts of gypsum, 10-30 parts of white mulberry root-bark, 10-30 parts of radix scutellariae, 5-25 parts of coptis chinensis, 10-30 parts of semen lepidii, 10-35 parts of rhizoma smilacis glabrae, 10-35 parts of bighead atractylodes rhizome, 10-35 parts of peanut bud, 10-45 parts of peanut bud, 15 parts of radish bud, 15-35 parts of radix codonopsis, 25 parts of radix codonopsis, 15-68 parts of rhizoma dioscoreae, 15-66 parts of rhizoma dioscoreae, 15-30 parts of semen raphani, 15-40 parts of medlar, 15-30 parts of Chinese date, 10-40 parts of loach peptide, 10-40 parts of oyster peptide, 25-65 parts of black sesame oil, 15-40 parts of xylitol and 1-15 parts of salt.
2. The medicinal and edible composition as claimed in claim 1, which is characterized by comprising the following raw materials in parts by weight:
13-20 parts of caulis spatholobi, 13-20 parts of purple perilla, 22-55 parts of radix bupleuri, 35-55 parts of rheum officinale, 26-38 parts of vortexes, 18-20 parts of cinnamon, 15-20 parts of dried ginger, 9-15 parts of asarum, 14-20 parts of ephedra, 16-20 parts of hollyhock, 10-20 parts of monkshood, 22-35 parts of dark plum, 13-19 parts of schisandra chinensis, 15-34 parts of laurel, 13-20 parts of selfheal, 13-20 parts of trichosanthes root, 13-20 parts of liquorice, 13-20 parts of pinellia ternate, 20-30 parts of radix puerariae, 10-20 parts of immature bitter orange, 8-15 parts of inkfish ink powder, 12-18 parts of radix angelicae, 59-75 parts of semen plantaginis, 28-36 parts of almond, 48-54 parts of gypsum, 13-20 parts of cortex mori, 13-20 parts of radix scutellariae, 8-15 parts of coptis chinensis, 13-20 parts of semen lepidii, 13-20 parts of rhizoma smilacis glabrae, 12-20 parts of bighead atractylodes rhizome, 20 parts of peanut buds, 20 parts of radish buds, 22 parts of radish 22 parts of radix codonopsis, 38-57 parts of Chinese yams, 41-59 parts of Chinese yams, 28-32 parts of medlar, 18-25 parts of Chinese date, 25-34 parts of loach peptide, 25-36 parts of oyster peptide, 44-57 parts of black sesame oil, 27-35 parts of xylitol and 4-10 parts of salt.
3. The composition as claimed in claim 1 or 2, wherein the radix Puerariae is radix Puerariae extract, the mume fructus is vinegar-soaked mume fructus, the radix Aconiti lateralis Preparata is radix Aconiti lateralis Preparata, and the Glycyrrhrizae radix is radix Glycyrrhizae Preparata.
4. The preparation method of the medicinal and edible composition as claimed in any one of claims 1-3, characterized in that the method comprises the following steps:
mixing fructus Jujubae, caulis Spatholobi, Perillae herba, bupleuri radix, radix et rhizoma Rhei, cortex Cinnamomi, Zingiberis rhizoma, herba asari, herba Ephedrae, radix Aconiti lateralis Preparata, Prunellae Spica, Trichosanthis radix, Glycyrrhrizae radix, rhizoma Pinelliae, radix Angelicae Dahuricae, semen plantaginis, Gypsum Fibrosum, cortex Mori, Scutellariae radix, Coptidis rhizoma, semen Lepidii, fructus Aurantii Immaturus, rhizoma Smilacis Glabrae, and Atractylodis rhizoma, and extracting with water to obtain a first mixture;
micronizing fructus Zanthoxyli, fructus Schisandrae chinensis, and fructus laurel to obtain a second mixture;
steaming mume fructus, semen Armeniacae amarum, Worm, peanut sprout, radix Raphani, radix Codonopsis, rhizoma Dioscoreae, and fructus Lycii, and grinding to obtain a third mixture;
mixing cuttlefish ink powder, loach peptide, oyster peptide, radix Puerariae, xylitol, and salt to obtain a fourth mixture;
and mixing the first mixture with the heated black sesame oil, uniformly stirring, mixing with the third mixture, continuously heating, adding the fourth mixture, stirring, adding the second mixture, and uniformly mixing to obtain the medicinal and edible composition.
5. The preparation method according to claim 4, wherein the dates are roasted before soaking, and the roasting temperature is 50-70 ℃.
6. The preparation method according to claim 4, wherein the water is extracted by a feed-liquid ratio of 1 g: (7-9) mL; the times of water extraction are 1-3 times, and the time of each water extraction is 1-1.5 h.
7. The method of claim 4, wherein the bell pepper is roasted before micronization, and the particle size of the micronized second mixture is less than or equal to 74 μm.
8. The production method according to claim 4, wherein the temperature of the heated black sesame oil is 40 to 60 ℃ and the temperature after the temperature rise is 70 to 85 ℃.
9. Use of the medicinal and edible composition as claimed in any one of claims 1-3 in the preparation of a medicament for preventing and treating neocoronavirus pneumonia variation or compound yang.
10. Use of the medicinal and edible composition as claimed in any one of claims 1-3 in food.
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Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111643645A (en) * | 2020-03-07 | 2020-09-11 | 深圳市三合九真健康管理有限公司 | Traditional Chinese medicine composition, decoction and granules for resisting COVID-19 |
CN112667922A (en) * | 2021-01-12 | 2021-04-16 | 山东大学 | Novel coronavirus traditional Chinese medicine formula recommendation method and system based on collaborative filtering |
WO2021169026A1 (en) * | 2020-02-24 | 2021-09-02 | 江苏省中医院 | Traditional chinese medicine composition for preventing epidemics, and preparation method therefor and use thereof |
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CN111643645A (en) * | 2020-03-07 | 2020-09-11 | 深圳市三合九真健康管理有限公司 | Traditional Chinese medicine composition, decoction and granules for resisting COVID-19 |
CN112667922A (en) * | 2021-01-12 | 2021-04-16 | 山东大学 | Novel coronavirus traditional Chinese medicine formula recommendation method and system based on collaborative filtering |
Non-Patent Citations (1)
Title |
---|
周宝宽;: "清肺排毒汤治疗新型冠状病毒肺炎机制解析", 辽宁中医药大学学报, vol. 22, no. 07, pages 13 - 19 * |
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CN116832066A (en) * | 2023-08-08 | 2023-10-03 | 青岛海洋生物医药研究院股份有限公司 | Application of cuttlefish ink extract in preparing medicine for treating hyperkinetic syndrome and depression |
CN116832066B (en) * | 2023-08-08 | 2024-01-12 | 青岛海洋生物医药研究院股份有限公司 | Application of cuttlefish ink extract in preparing medicine for treating hyperkinetic syndrome and depression |
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