CN114712668A - Tumor body internal directional perfusion chemotherapy indwelling tube - Google Patents
Tumor body internal directional perfusion chemotherapy indwelling tube Download PDFInfo
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- CN114712668A CN114712668A CN202110351763.0A CN202110351763A CN114712668A CN 114712668 A CN114712668 A CN 114712668A CN 202110351763 A CN202110351763 A CN 202110351763A CN 114712668 A CN114712668 A CN 114712668A
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- indwelling
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- 206010028980 Neoplasm Diseases 0.000 title claims abstract description 51
- 238000002512 chemotherapy Methods 0.000 title claims abstract description 26
- 230000010412 perfusion Effects 0.000 title claims abstract description 15
- 239000003814 drug Substances 0.000 claims abstract description 11
- 229940044683 chemotherapy drug Drugs 0.000 claims abstract description 8
- 238000002679 ablation Methods 0.000 claims abstract description 7
- 239000007788 liquid Substances 0.000 claims abstract description 5
- 238000003384 imaging method Methods 0.000 claims abstract description 4
- 239000002504 physiological saline solution Substances 0.000 claims abstract description 3
- 239000007924 injection Substances 0.000 claims description 6
- 238000002347 injection Methods 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 4
- 230000000694 effects Effects 0.000 claims description 3
- 238000002560 therapeutic procedure Methods 0.000 claims 2
- 230000000903 blocking effect Effects 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 210000000056 organ Anatomy 0.000 abstract description 6
- 229940079593 drug Drugs 0.000 abstract description 4
- 210000005077 saccule Anatomy 0.000 abstract description 4
- 238000001802 infusion Methods 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 description 8
- 206010058467 Lung neoplasm malignant Diseases 0.000 description 3
- 201000007270 liver cancer Diseases 0.000 description 3
- 208000014018 liver neoplasm Diseases 0.000 description 3
- 201000005202 lung cancer Diseases 0.000 description 3
- 208000020816 lung neoplasm Diseases 0.000 description 3
- 210000004881 tumor cell Anatomy 0.000 description 3
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 230000000241 respiratory effect Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 238000011298 ablation treatment Methods 0.000 description 1
- 210000001185 bone marrow Anatomy 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3415—Trocars; Puncturing needles for introducing tubes or catheters, e.g. gastrostomy tubes, drain catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
- A61M25/0074—Dynamic characteristics of the catheter tip, e.g. openable, closable, expandable or deformable
- A61M25/0075—Valve means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
- A61M25/0074—Dynamic characteristics of the catheter tip, e.g. openable, closable, expandable or deformable
- A61M25/0075—Valve means
- A61M2025/0076—Unidirectional valves
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Child & Adolescent Psychology (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
The invention discloses a directional perfusion chemotherapy indwelling tube in a tumor body, which specifically comprises the following use steps: 1) ablation is first performed over a large area to the interior of the tumor. 2) The chemotherapy indwelling tube is sleeved on the puncture needle, the tail end of the needle tip is placed into a proper position in the tumor in the aspect of imaging positioning, and the physiological saline is injected into the balloon, so that the proximal tube is fixed in the tumor body. 2) The puncture needle is pulled out, the one-way valve is closed, the distal tube is fixed on the skin, and the chemotherapy drugs are filled into the tumor body through the tail end of the distal tube and clamped. 3) The chemotherapy can adjust the amount and frequency of local drug infusion according to the tolerance of a patient, periodically infuse drugs into the tumor body through the tube, and pump out the liquid in the balloon after reaching a period to pull out the tube. The invention has the advantages that: fixing the chemotherapy indwelling tube in the tumor body by utilizing the saccule; the indwelling tube is divided into a proximal tube and a distal tube, and a slide way is arranged at the joint of the two tubes, so that the traction feeling is avoided when the organ moves; the end of the proximal tube is provided with a one-way valve which can prevent the tube from being blocked.
Description
Technical Field
The invention relates to a directional perfusion chemotherapy indwelling tube in a tumor body.
Background
At present, with the development of interventional technology, many tumors can be subjected to percutaneous interventional ablation treatment, including liver cancer, lung cancer and the like. For tumors with huge body types and invading peripheral tissues, especially when important tissues and organs exist around the tumors, the tumors cannot be completely killed, and local normal tissues can be accidentally injured, so that dysfunction is caused. The ablation is to kill cells indiscriminately, while the chemotherapy drug has certain targeting property, the probability of killing tumor cells is relatively high between the tumor cells and normal cells, and the side effect of the whole-body chemotherapy is large, which is easy to cause symptoms such as bone marrow suppression, nerve gastrointestinal tract and the like. Local perfusion chemotherapy mainly generates higher concentration locally through the diffusion of tumor drugs, kills adjacent tumor cells, and has lower concentration on the whole body and smaller side effect. Local perfusion belongs to the chronic mode of killing the tumour, and the patient can face repeated puncture risk, causes unnecessary damage, and the internal portion of tumour puts the pipe, this problem of avoidance that can be fine.
Disclosure of Invention
The invention aims to provide a directional perfusion chemotherapy indwelling tube in a tumor body, which solves the problems in the technical background: prior to use, ablation (thermal or chemical) is performed to the interior of the tumor with ablation. Then, the needle channel is processed for tumor elimination to avoid tumor dissemination, and the follow-up steps are as follows:
1. the proximal end of the indwelling tube is provided with a one-way valve which allows the solution to flow in one way, the chemotherapy indwelling tube is sleeved on the puncture needle, the tail end of the needle point is placed into a proper position in the tumor in the aspect of imaging positioning, and the balloon is injected with normal saline to fix the proximal tube in the tumor body.
2. The puncture needle is pulled out, the check valve is closed, the distal tube is fixed on the skin, the chemotherapy drugs are poured into the tumor body through the tail end of the distal tube, the check valve is opened, and after the drug pouring is finished, the check valve is closed to prevent turbid tissues such as blood from flowing back to the inside of the pipeline, so that the blockage of the tube is caused.
3. After the chemotherapy drugs are applied, the distal tube is clamped closed by a clamp on the distal tube.
4. Some tumor bodies are positioned in movable organs, such as lung cancer, liver cancer and the like, and move along with respiratory movement, and because the slide way exists, the tissue can not be pulled.
5. The chemotherapy can adjust the dosage of local medicine according to the tolerance of a patient, the medicine is periodically filled into the tumor body through the tube, and after the period is reached, the liquid in the saccule is pumped out, and the indwelling tube is pulled out.
The invention has the advantages that: fixing the chemotherapy indwelling tube in the tumor body by utilizing the saccule; the indwelling tube is divided into a proximal tube and a distal tube, and a slide way is arranged at the joint of the two tubes, so that the traction feeling is avoided when the organ moves; the end of the proximal tube is provided with a one-way valve which can prevent the tube from being blocked. The method can solve the problem of long-term local chemotherapy, can finish the incomplete ablation of the complicated tissue structure around the tumor, and has wide application value.
Drawings
The accompanying drawings, which are incorporated in and constitute a part of this application, illustrate an embodiment of the invention and, together with the description, serve to explain the invention and not to limit the invention.
FIG. 1 is a directional perfusion chemotherapy indwelling tube in tumor body
1. One-way valve, 2 balloon, 3 proximal tube, 4 slideway, 5 distal tube, 6 clip, 7 balloon water injection tube
Detailed Description
Detailed description of the preferred embodimentsthe following detailed description is to be construed as exemplary and is intended to provide further explanation of the invention as claimed. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. It is noted that the terms used herein are merely intended to describe particular embodiments and are not intended to limit exemplary embodiments according to the present application as used herein, the singular is intended to include the plural unless the context clearly indicates otherwise, and it should be further understood that when the terms "comprises" and/or "comprising" are used in this specification, they specify the presence of features, steps, operations, devices, components and/or combinations thereof.
The method for injecting the medicament in the tumor body by using the directional injection chemotherapy indwelling tube in the tumor body comprises the following steps:
1. the one-way valve 1 at the head end of the proximal tube 3 is an elastic structure which can be opened and closed, the chemotherapy indwelling tube is sleeved on the puncture needle, the tail end of the needle point is arranged at a proper position in the tumor in the aspect of imaging positioning, and the physiological saline is injected into the balloon through the balloon water injection tube 7, so that the proximal tube is fixed in the tumor.
2. The puncture needle is pulled out, the one-way valve 1 is closed, the distal tube 5 is fixed on the skin, and the chemotherapy drugs are perfused into the tumor body through the tail end of the distal tube 5.
3. After the chemotherapy drug is administered, the distal tube 5 is clamped closed by the clamp 6 on the distal tube.
4. Some tumor bodies are positioned in movable organs, such as lung cancer, liver cancer and the like, and move along with respiratory movement, and because the slide way 4 exists, the tissues can not be pulled.
5. The one-way valve 1 enables water in the tube to flow to the interior of the tumor body, and prevents turbid materials such as blood from flowing back to the interior of the tube, so that the tube is blocked.
6. The chemotherapy can adjust the dosage of local medicine according to the tolerance of a patient, the medicine is periodically filled into the tumor body through the tube, and after the period is reached, the liquid in the balloon 2 is pumped out through the balloon water injection tube 7, and the tube is pulled out.
The invention has the advantages that: fixing the chemotherapy indwelling tube in the tumor body by utilizing the saccule; the indwelling tube is divided into a proximal tube and a distal tube, and a slide way is arranged at the joint of the two tubes, so that the traction feeling is avoided when the organ moves; the end of the proximal tube is provided with a one-way valve which can prevent the tube from being blocked. The method can solve the problem of long-term local chemotherapy, can finish the incomplete ablation of the complicated tissue structure around the tumor, and has wide application value.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.
Claims (6)
1. The utility model provides a directional perfusion chemotherapy indwelling tube in tumor body which characterized in that specifically includes:
the device comprises a one-way valve, a balloon, a proximal tube, a slide way, a distal tube, a clamp, a balloon water injection tube and the like.
2. The indwelling catheter for perfusion therapy in vivo as claimed in claim 1, wherein the one-way valve at the proximal end of the catheter is an elastic structure that can be opened and closed, and the inside of the indwelling catheter can be opened when pressure is applied, and can be closed when pressure disappears, so as to prevent turbid tissues and liquid at the proximal end from blocking the catheter.
3. The indwelling tube for perfusion therapy within the body of a tumor according to claim 1, wherein the proximal tube and the distal tube are connected by a slide, and when the proximal tube is fixed inside the tumor body and the distal tube is fixed on the skin, the length of the tube can be freely changed.
4. The indwelling catheter for directional perfusion in tumor body according to claim 1, wherein the proximal tube is fixed inside the tumor body by balloon water injection.
5. The indwelling tube for directional perfusion chemotherapy in a tumor body according to claim 1, wherein the surfaces of the proximal tube, the balloon and the distal tube are smooth, which facilitates tube drawing after local perfusion chemotherapy.
6. The method for using the directional perfusion chemotherapy indwelling tube in the tumor body according to any one of the claims 1 to 5, is characterized by comprising the following steps: 1) after tumor ablation, sleeving a chemotherapy indwelling catheter on a puncture needle, placing the tail end of a needle tip into a proper position in a tumor in the aspect of imaging positioning, injecting physiological saline into a balloon of a proximal tube, and fixing the proximal tube in a tumor body; 2) the puncture needle is pulled out, the one-way valve is closed, the distal tube is fixed on the skin, the chemotherapy drugs are infused into the tumor body through the tail end of the distal tube, and the one-way valve is opened under the action of pressure; 3) after the chemotherapy drugs are applied, the one-way valve is closed, and the clamp on the tail end of the distal tube is clamped; 4) the chemotherapy can adjust the dosage of local medicine according to the tolerance of the patient, the medicine is periodically filled into the tumor body through the tube, and after the treatment effect is achieved, the liquid in the balloon is pumped out, and the tube is pulled out.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110351763.0A CN114712668A (en) | 2021-03-31 | 2021-03-31 | Tumor body internal directional perfusion chemotherapy indwelling tube |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110351763.0A CN114712668A (en) | 2021-03-31 | 2021-03-31 | Tumor body internal directional perfusion chemotherapy indwelling tube |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN114712668A true CN114712668A (en) | 2022-07-08 |
Family
ID=82234561
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110351763.0A Pending CN114712668A (en) | 2021-03-31 | 2021-03-31 | Tumor body internal directional perfusion chemotherapy indwelling tube |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114712668A (en) |
-
2021
- 2021-03-31 CN CN202110351763.0A patent/CN114712668A/en active Pending
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| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20220708 |
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