Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition for treating arthralgia and myalgia, which is prepared by combining a plurality of medicinal materials according to the principle of external treatment along the channels of promoting blood circulation to remove blood stasis, promoting qi circulation to relieve pain and clearing and activating the channels and collaterals in the traditional Chinese medicine, can effectively improve local qi and blood circulation of premonitory parts of osteoarticular diseases, has the characteristics of strong permeability, quick response, high cure rate, convenience in use and difficulty in relapse, and is suitable for relieving various pains caused by various reasons of wind-cold-dampness arthralgia.
The second purpose of the invention is to provide a traditional Chinese medicine preparation containing the traditional Chinese medicine composition.
The third purpose of the invention is to provide the application of the traditional Chinese medicine composition, in particular to the application in preparing medicines for treating osteoarticular diseases and traumatic injuries.
In order to achieve the purpose, the invention adopts the following technical scheme:
a traditional Chinese medicine composition for treating arthralgia and myalgia comprises the following raw materials:
2-8 parts of obscured homalomena rhizome, 2-8 parts of tripterygium wilfordii, 1-5 parts of pubescent angelica root, 1-5 parts of notopterygium root, 1-5 parts of corydalis tuber, 1-5 parts of safflower, 1-5 parts of garden balsam stem, 0.5-5 parts of drynaria rhizome, 0.5-5 parts of beautiful sweetgum fruit, 0.5-5 parts of asarum, 0.5-5 parts of east Asian tree fern rhizome, 0.5-5 parts of rhizome of yam, 0.5-5 parts of szechuan lovage rhizome, 0.5-5 parts of angelica, 0.5-5 parts of suberect spatholobus stem, 0.5-5 parts of common clubmoss herb, 0.3-3 parts of mulberry twig, 0.3-3 parts of angelica root, 0.3-3 parts of peach kernel, 0.3-3 parts of himalayan teasel root, 0.3-3 parts of large-leaf gentian root, 0.3-3 parts of eucommia bark, 0.3-3 parts of red peony root, 0.3 to 3 portions of argyi leaf, 0.3 to 3 portions of achyranthes root, 0.3 to 3 portions of mistletoe, 0.3 to 3 portions of costustoot, 0.3 to 3 portions of pine nodular branch, 0.3 to 3 portions of pawpaw, 0.3 to 3 portions of liquorice, 0.5 to 5 portions of myrrh, 0.5 to 5 portions of frankincense, 0.5 to 5 portions of scorpion, 0.5 to 5 portions of borneol, 0.2 to 2 portions of earthworm, 0.2 to 2 portions of zaocys dhumnade, 0.1 to 1 portion of long-noded pit viper, 0.1 to 1 portion of ground beetle, 0.1 to 1 portion of leech, 0.1 to 1 portion of scorpion, and 0.1 to 1 portion of centipede.
Preferably, the traditional Chinese medicine composition for treating arthralgia and myalgia comprises the following raw material components:
3-5 parts of obscured homalomena rhizome, 3-5 parts of tripterygium wilfordii, 2-4 parts of pubescent angelica root, 2-4 parts of notopterygium root, 2-4 parts of corydalis tuber, 2-4 parts of safflower, 2-4 parts of garden balsam stem, 1-3 parts of drynaria rhizome, 1-3 parts of beautiful sweetgum fruit, 1-3 parts of asarum, 1-3 parts of cibotium rhizome, 1-3 parts of yam rhizome, 1-3 parts of szechuan lovage rhizome, 1-3 parts of angelica, 1-3 parts of suberect spatholobus stem, 1-3 parts of lycopodium clavatum, 0.5-1.5 parts of mulberry twig, 0.5-1.5 parts of angelica root, 0.5-1.5 parts of dipsacus root, 0.5-1.5 parts of peach kernel, 0.5-1.5 parts of largeleaf gentian root, 0.5-1.5 parts of eucommia bark, 0.5-1.5 parts of red peony root, 0.5 to 1.5 parts of argyi leaf, 0.5 to 1.5 parts of twotooth achyranthes root, 0.5 to 1.5 parts of Chinese taxillus twig, 0.5 to 1.5 parts of costustoot, 0.5 to 1.5 parts of pine nodular branch, 0.5 to 1.5 parts of pawpaw, 0.5 to 1.5 parts of liquorice, 1 to 3 parts of myrrh, 1 to 3 parts of frankincense, 1 to 3 parts of bloody scorpion, 1 to 3 parts of borneol, 0.5 to 1.5 parts of earthworm, 0.5 to 1.5 parts of zaocys dhumnade, 0.3 to 0.8 parts of long-noded pit viper, 0.3 to 0.8 parts of ground beetle, 0.3 to 0.8 parts of leech, 0.3 to 0.8 parts of scorpion, and 0.3 to 0.8 parts of centipede.
Preferably, the traditional Chinese medicine composition for treating arthralgia and myalgia comprises the following raw material components:
4 parts of homalomena rhizoma, 4 parts of tripterygium wilfordii, 3 parts of pubescent angelica root, 3 parts of notopterygium root, 3 parts of corydalis tuber, 3 parts of safflower, 3 parts of garden balsam stem, 2 parts of drynaria rhizome, 2 parts of beautiful sweetgum fruit, 2 parts of asarum, 2 parts of east Asian tree fern rhizome, 2 parts of rhizome of yam, 2 parts of szechuan lovage, 2 parts of angelica, 2 parts of suberect spatholobus stem, 2 parts of common clubmoss herb, 1 part of mulberry twig, 1 part of dahurian angelica root, 1 part of peach kernel, 1 part of himalayan teasel root, 1 part of large-leaved gentian, 1 part of eucommia bark, 1 part of red paeony root, 1 part of argy leaf, 1 part of twotooth achyranthes root, 1 part of Chinese taxillus twig, 1 part of costustoot, 1 part of pine nodular branch, 1 part of common floweringquince fruit, 1 part of licorice root, 2 parts of myrrh, 2 parts of frankincense, 2 parts of bloody scorpion, 2 parts of borneol, 1 part of earthworm, 1 part of black snake, 1 part of black-tail snake, black-bone and black-bone, 0.5 part of long-noded pit viper, 0.5 part of ground beeltle, 0.5 part of leech, 0.5 part of scorpion and 0.5 part of centipede.
The traditional Chinese medicine composition for treating arthralgia and myalgia, provided by the invention, is rhizoma homalomenae, and has the effects of dispelling wind and eliminating dampness, relieving swelling and pain, and strengthening muscles and bones; tripterygium wilfordii hook F.H. capable of dispelling wind and removing dampness, dredging collaterals and relieving pain, clearing heat and detumescence, removing toxicity and killing parasites, and the two are monarch drugs. Radix Angelicae Pubescentis, Notopterygii rhizoma, herba asari, fructus Lipuidambaris, rhizoma corydalis, Carthami flos, herba Speranskiae Tuberculatae, rhizoma Dioscoreae Septemlobae, rhizoma Ligustici Chuanxiong, herba Lycopodii, lignum Pini nodi, radix Angelicae Dahuricae, and radix aucklandiae, and Olibanum, Myrrha, sanguis Draxonis, Borneolum Syntheticum, and semen Persicae can dispel blood stasis, dredge channels, relieve swelling and promote granulation; the Chinese medicinal composition is prepared from zaocys dhumnade, long-noded pit viper, ground beeltle, leech, centipede, scorpion, earthworm, for dispelling wind and calming endogenous wind, expelling wind and relieving convulsion, relieving pain by wandering, penetrating bones and muscles, and arresting convulsion, wherein the medicaments are mutually in harmony and mutually complementary and are used as ministerial medicaments. Radix Dipsaci, Eucommiae cortex, herba Taxilli, rhizoma Drynariae, rhizoma Cibotii, and fructus Chaenomelis for nourishing liver and kidney, and strengthening tendons and bones; chinese angelica, radix paeoniae rubrathe, spatholobus stem and achyranthes root, radix angelicae sinensis, radix paeoniae rubrathe, caulis spatholobi and achyranthes root, radix achyranthis bidentatae, all of which are used as adjuvant drugs for nourishing blood and promoting blood circulation. Ramulus Mori, radix Gentianae Macrophyllae, and radix Glycyrrhizae have effects of strengthening tendons and bones, relieving swelling, and benefiting joint, and are used as guiding drugs in combination with other drugs. The medicines are combined to play the effects of dispelling wind and eliminating dampness, dredging collaterals and relieving pain, promoting blood circulation and removing blood stasis, reducing swelling and promoting tissue regeneration, calming wind and relieving convulsion, strengthening tendons and tonifying kidney.
The traditional Chinese medicine composition for treating arthralgia and myalgia, provided by the invention, has large compatibility due to the cold nature and strong toxicity of the tripterygium wilfordii, and has a large number of special effects and mutual reinforcement ministerial drugs for reducing toxicity and enhancing efficacy. Multiple auxiliary medicines for nourishing and benefiting are added to restrict the residual of the drastic effect of the repairing medicine. The guiding drug can be better combined with the other drugs to induce the penetration of the distal tip and strengthen the tendons, bones and joints.
In order to facilitate understanding of the present invention, the raw material drugs and the drug effects of the present invention will now be further described.
Qiannianjian, bitter and pungent in flavor and warm in nature. It enters liver and kidney meridians. Dispel wind-damp, strengthen tendons and bones. It is indicated for arthralgia due to wind-cold-dampness, cold pain of waist and knees, spasm and numbness of lower limbs.
Tripterygium wilfordii, bitter and pungent in flavor, cool in nature. It enters liver and kidney meridians. Dispelling pathogenic wind and removing dampness, promoting blood circulation and removing obstruction in collaterals, relieving swelling and pain, killing parasites and removing toxic substance. Can be used for treating rheumatoid and rheumatic arthritis, glomerulonephritis, nephrotic syndrome, intractable headache and body pain, lupus erythematosus, Behcet disease, psoriasis, leprosy, eczema, scabies, intractable tinea, and venomous snake bite.
Du Huo is pungent and bitter in flavor and slightly warm in nature. It enters kidney and bladder meridians. Dispel wind and dampness, relieve arthralgia and alleviate pain. Can be used for treating arthralgia due to wind-cold-dampness, lumbago, gonalgia, headache due to wind-cold-yin deficiency, and headache due to wind-cold-dampness.
Qiang Huo is pungent and bitter in flavor and warm in nature. Enter bladder and kidney meridians. Relieve exterior syndrome, dispel cold, expel wind and remove dampness, and alleviate pain. Wind-cold type common cold, wind-cold-dampness arthralgia, stiff neck, spasm of tendons and tendons, soreness and pain of joints, edema due to wind-damp, superficial infection and sore-toxin.
Corydalis tuber, pungent and bitter in flavor and warm in nature. It enters liver and spleen meridians. Activate blood, move qi and alleviate pain. Can be used for treating chest and hypochondrium, abdominal pain, thoracic obstruction, cardialgia, amenorrhea, dysmenorrhea, puerperal blood stasis, traumatic injury, and swelling and pain.
Safflower, pungent in flavor and warm in nature. It enters heart and liver meridians. Promote blood circulation to remove blood stasis and dredge meridians. Can be used for treating amenorrhea due to blood stagnation, puerperal blood stasis, abdominal mass, traumatic injury, pain, measles without adequate eruption.
Speranskia herb, pungent in flavor and warm in nature. Enter liver and kidney meridians. Dispelling pathogenic wind and removing dampness, relieving rigidity of muscles and promoting blood circulation, removing blood stasis and detumescence, removing toxic substance and relieving pain. Rheumatic arthralgia, contracture of muscles and bones, cold-dampness beriberi, waist sprain, paralysis, amenorrhea, eczema of scrotum, sore and furuncle pyogenic infections.
Drynaria rhizome, bitter in taste and warm in nature. It enters liver and kidney meridians. Promoting blood circulation and removing blood stasis. Tonify kidney, strengthen bone, heal wound and alleviate pain. For: lumbago due to kidney deficiency, tinnitus, deafness, loose teeth, traumatic injury, contusion, and fracture of bones and muscles; it is used externally to treat alopecia areata and vitiligo.
Lu Lian Tong is bitter in taste and neutral in nature. The liver and kidney meridians. Dispel wind, activate collateral flow, induce diuresis, dredge meridians. Can be used for treating arthralgia, numbness, spasm, edema, distention, oliguria, and amenorrhea.
Asarum herb, wild ginger, pungent in flavor and warm in nature. It enters heart, lung and kidney meridians. Relieving exterior syndrome, dispelling cold, dispelling pathogenic wind, relieving pain, dredging orifices, warming lung, and eliminating phlegm. Can be used for treating wind-cold type common cold, headache, toothache, rheumatalgia, nasosinusitis, and cough due to lung cold.
Cibotium barometz is bitter and sweet in taste and warm in nature. It enters liver and kidney meridians. Dispel wind-damp, tonify liver and kidney, strengthen waist and knees. Can be used for treating rheumatalgia, soreness of waist and knees, and weakness of lower limbs.
Bi Xie is bitter in flavor and neutral in nature. It enters kidney and stomach meridians. Induce diuresis to remove turbid pathogen, dispel wind to remove arthralgia. Can be used for treating stranguria caused by chyluria, whitish and turbid urine, leukorrhagia, rheumatic arthralgia, joint discomfort, and pain in waist and knees.
Chuan Xiong is pungent in flavor and warm in nature. It enters liver, gallbladder and pericardium meridians. Promote blood circulation and move qi, dispel wind and alleviate pain. Can be used for treating menoxenia, hypochondriac pain, thoracic obstruction, pyocutaneous disease, swelling and pain, traumatic injury, headache, and rheumatalgia.
Dang Gui is sweet and pungent in flavor and warm in nature. It enters liver, heart and spleen meridians. Tonify blood and activate blood, regulate menstruation and alleviate pain, moisten intestines and relax bowel. Can be used for treating blood deficiency, sallow complexion, giddiness, palpitation, menoxenia, amenorrhea, dysmenorrhea, asthenia cold, abdominal pain, rheumatalgia, traumatic injury, superficial infection, pyocutaneous disease, intestinal dryness, and constipation.
Spatholobus stem, bitter in taste, slightly sweet and warm in nature. It enters liver meridian. Promote blood circulation, enrich blood, relax tendons and activate collaterals. Can be used for treating menoxenia, amenorrhea due to blood deficiency, rheumatalgia, and apoplexy.
Lycopodium clavatum, bitter and slightly pungent in flavor, warm in nature. Dispel wind and dampness, relax tendons and activate collaterals. Can be used for treating joint pain and difficulty in flexion and extension.
Mulberry twig, slightly bitter in taste, mild in nature. It enters liver meridian. Dispel wind-damp and benefit joints. Can be used for treating rheumatism, shoulder pain, arm pain, and arthralgia.
Bai Zhi is pungent in flavor and warm in nature. It enters lung, spleen and stomach meridians. Relieving exterior syndrome, dispelling cold, dispelling pathogenic wind, relieving pain, dredging nasal orifice, eliminating dampness, relieving leukorrhagia, relieving swelling, expelling pus, dispelling pathogenic wind, and relieving itching. Can be used for treating wind-cold type common cold, headache, toothache, rheumatalgia, nasosinusitis, leukorrhagia, sore, carbuncle, and toxic swelling.
Tao ren is bitter and sweet in flavor and neutral in nature. It enters heart, liver and large intestine meridians. Promote blood circulation to remove blood stasis, moisten intestines to relieve constipation, and relieve cough and dyspnea. Can be used for treating amenorrhea, dysmenorrhea, abdominal mass, pulmonary abscess, intestinal carbuncle, traumatic injury, intestinal dryness, constipation, cough, and asthma.
Xu Duan is bitter, sweet and pungent in flavor and slightly warm in nature. It enters liver and kidney meridians. Tonify liver and kidney, promote blood circulation, and nourish tendons and bones. Can be used for treating soreness of waist and knees, rheumatic arthralgia, traumatic injury, and swelling and pain due to fracture.
Gentiana macrophylla, bitter and pungent in flavor and slightly cold in nature. It enters stomach, liver and gallbladder meridians. Dispel wind-damp, relax muscles and tendons, dredge collaterals, clear deficiency heat. Can be used for treating rheumatalgia, joint spasm, limb paralysis, hectic fever due to yin-deficiency, and jaundice due to damp-heat.
Du Zhong is sweet and slightly pungent in flavor and warm in nature. Enter liver and kidney meridians. Tonify liver and kidney, strengthen tendons and bones, prevent abortion. It is indicated for soreness and pain of lumbar and knees, atrophy and weakness of feet and knees, dribbling urination, itching of vulva, vaginal bleeding, threatened abortion, and hypertension.
Red peony root, bitter in taste and slightly cold in nature. It enters liver meridian. Clear heat and cool blood, dissipate blood stasis and alleviate pain. Can be used for treating heat entering nutrient-blood, macula due to warm toxin, hematemesis and epistaxis, conjunctival congestion and swelling and pain, liver depression and hypochondriac pain, amenorrhea and dysmenorrhea, addictions and abdominal pain, traumatic injury, carbuncle, swelling, sore and ulcer.
Mugwort leaf, pungent and bitter in flavor and warm in nature. It enters liver, spleen and kidney meridians. Warming channels to stop bleeding, dispelling cold and relieving pain; externally used for eliminating dampness and relieving itching. Can be used for treating hematemesis, epistaxis, metrorrhagia, menorrhagia, vaginal bleeding, lower abdomen psychroalgia, menoxenia, and infertility due to cold womb; it can be used for treating skin pruritus. Vinegar moxa charcoal can warm meridians and stop bleeding, and is indicated for bleeding due to deficiency-cold.
Niu xi is bitter, sweet and sour in taste and neutral in nature. It enters liver and kidney meridians. Dispel blood stasis and dredge channels, tonify liver and kidney, strengthen tendons and bones, induce diuresis and treat stranguria, and draw blood downward. Can be used for treating amenorrhea, dysmenorrhea, soreness of waist and knees, myasthenia of bones and muscles, stranguria, edema, headache, vertigo, toothache, skin ulcer, hematemesis, and epistaxis.
Sang Ji Sheng is bitter and sweet in flavor and neutral in nature. It enters liver and kidney meridians. Dispel wind-damp, tonify liver and kidney, strengthen tendons and bones, and prevent abortion. Can be used for treating rheumatalgia, soreness of waist and knees, weakness of bones and muscles, metrorrhagia, metrostaxis, pregnant hemorrhage, threatened abortion, and dizziness.
Mu Xiang is pungent and bitter in flavor and warm in nature. It enters spleen, stomach, large intestine and gallbladder meridians. Move qi and alleviate pain, regulate middle energizer and disperse stagnation. Can be used for treating abdominal distention and pain, dysentery, diarrhea, abdominal distention, spleen deficiency, anorexia, hypochondriac pain, and jaundice.
Loose knot, bitter taste and warm nature. It enters liver and kidney meridians. Dispel wind and dry dampness, relax muscles and tendons, dredge collaterals, activate blood and alleviate pain. Wind-cold-dampness arthralgia, flaccidity of feet, traumatic injury and pain.
Pawpaw, sour, warm. It enters liver and spleen meridians. Relaxing tendons and activating collaterals, resolving dampness and regulating stomach. Can be used for treating rheumatalgia, spasm of muscles and tendons, swelling and pain of tinea pedis, vomiting, diarrhea and spasm of tendons.
Licorice root, radix Glycyrrhizae is sweet in flavor and neutral in nature. It enters heart, lung, spleen and stomach meridians. Invigorating spleen and replenishing qi, clearing away heat and toxic material, eliminating phlegm and relieving cough, relieving spasm and pain, and harmonizing the drugs. Can be used for treating weakness of spleen and stomach, asthenia, palpitation, short breath, cough, excessive phlegm, abdominal and limb spasm, pain, carbuncle, swelling, sore, and drug toxicity and strong nature.
Mo Yao, pungent and bitter in flavor and neutral in nature. It enters heart, liver and spleen meridians. Dispel stasis, relieve pain, resolve swelling and promote tissue regeneration. Can be used for treating thoracic obstruction, cardialgia, gastralgia, dysmenorrhea, amenorrhea, puerperal blood stasis, abdominal mass, rheumatic arthralgia, traumatic injury, carbuncle, swelling, and pyocutaneous disease.
Ru Xiang is pungent and bitter in flavor and warm in nature. It enters heart, liver and spleen meridians. Promoting blood circulation, relieving pain, eliminating swelling, and promoting granulation. Can be used for treating dysmenorrhea, amenorrhea, gastralgia, rheumatic arthralgia, traumatic injury, carbuncle, swelling, and pyocutaneous disease.
Xue Xie is sweet, salty and neutral in nature. It enters heart and liver meridians. Removing blood stasis, relieving pain, stopping bleeding, and promoting fluid production. Can be used for treating traumatic injury, internal injury, blood stasis, traumatic hemorrhage, skin ulcer, abscess, and unhealed ulcer.
Borneol, pungent and bitter in flavor and slightly cold in nature. It enters heart, spleen and lung meridians. Induce resuscitation and refresh mind, clear heat and alleviate pain. Can be used for treating fever unconsciousness, convulsion, apoplexy with phlegm syncope, qi stagnation and sudden syncope, central nausea and coma, thoracic obstruction, cardialgia, conjunctival congestion, aphtha, sore throat, and purulence in ear canal.
Di Long, salty in flavor and cold in nature. It enters liver, spleen and bladder meridians. Clear heat and stop endogenous wind, relieve dyspnea, dredge collaterals and induce diuresis. Can be used for treating infantile convulsion, tetany, cough and asthma due to lung heat, arthralgia, hemiplegia, and retention of heat in urine.
Zaocys dhumnades is sweet in taste and neutral in nature. Enter lung, spleen and liver meridians. Dispel wind-damp, unblock collaterals and stop convulsions. Stubborn rheumatism, numbness of skin, spasm of muscles and tendons, paralysis of limbs, tetanus, leprosy, rubella, scabies and tinea.
Agkistrodon, sweet in flavor, salty in taste and warm in nature. Enter liver and spleen meridians. Dispel wind, unblock collaterals, stop convulsions. Can be used for treating rheumatism, numbness, spasm, facial distortion, hemiplegia, convulsion, tetanus, leprosy, scabies, lymphoid tuberculosis, and malignant sore.
Eupolyphaga Seu Steleophaga is salty in flavor and cold in nature. Break blood and remove stasis, reunion of fractured tendons and bones. Can be used for treating amenorrhea, abdominal mass, puerperal stagnation, fracture, and pain.
Leech, salty and bitter in taste, neutral in nature. It enters liver meridian. Break blood and dredge channels, dispel stasis and eliminate disease. Can be used for treating amenorrhea due to blood stasis, addiction to abdominal mass, apoplexy, hemiplegia, traumatic injury.
Quan Xie is pungent in flavor and neutral in nature. Is toxic. It enters liver meridian. To stop endogenous wind and relieve convulsion, remove toxicity and resolve masses, dredge collaterals and alleviate pain. Can be used for treating acute and chronic infantile convulsion, facial distortion, tetanus, pyocutaneous disease, swelling and pain, lymphoid tuberculosis, migraine, headache, and rheumatalgia.
Wu Gong is pungent in flavor and warm in nature. It enters liver meridian. Extinguish wind and relieve spasm, dredge collaterals and alleviate pain, counteract toxic pathogen and dissipate nodulation. Can be used for treating endogenous liver wind, spasm, convulsion, infantile convulsion, apoplexy, hemiplegia, tetanus, rheumatism, headache, pyocutaneous disease, lymphoid tuberculosis, snake and insect bite.
The traditional Chinese medicine composition provided by the invention can be added with pharmaceutically conventional auxiliary materials or carriers and prepared into external preparations suitable for medicine according to conventional preparation technology, including but not limited to ointment, tincture and powder. Preferably, the traditional Chinese medicine composition is an ointment, so that the invention also provides a traditional Chinese medicine preparation taking the traditional Chinese medicine composition as a medicine active ingredient.
The invention also provides a preparation method of the external ointment taking the traditional Chinese medicine composition as an active ingredient, which comprises the following steps:
(1) weighing the raw materials respectively, drying and crushing the raw materials respectively to obtain raw material fine powder, preferably, the particle size of the raw material fine powder is 80-120 meshes, and more preferably 100 meshes; uniformly mixing the fine powder of each raw material to obtain mixed medicinal powder;
(2) adding Chinese liquor into the mixed medicinal powder, stirring, standing, adding molten Vaseline, and stirring to obtain paste. Preferably, the white spirit is over 60 degrees, the standing is carried out under a sealed condition, and the standing time is 5-9 days; the ratio of the mass of the mixed medicinal powder, the volume of the white spirit and the mass of the vaseline is preferably 1.5-2.5:1:0.3, and more preferably 2:1: 0.3.
The invention also provides application of the traditional Chinese medicine composition, in particular application in preparing medicines for treating bone joint diseases and traumatic injuries, wherein the bone joint diseases comprise but are not limited to cervical spondylosis, lumbar spondylosis, scapulohumeral periarthritis, knee joint diseases and tenosynovitis.
The invention has the beneficial effects that:
the traditional Chinese medicine composition for treating arthralgia and myalgia adopts obscured homalomena rhizome, thunder god vine, doubleteeth pubescent angelica root, incised notopterygium rhizome, corydalis tuber, safflower, garden balsam stem, fortune's drynaria rhizome, beautiful sweetgum fruit, manchurian wildginger, east Asian tree fern rhizome, Szechuan lovage rhizome, Chinese angelica, suberect spatholobus stem, common clubmoss herb, mulberry twig, dahurian angelica root, peach seed, himalayan teasel root, large-leaf gentian root, eucommia bark, red paeony root, Chinese mugwort leaf, twotooth achyranthes root, Chinese taxillus twig, costustoot, pine node, common floweringquince fruit, liquoric root, myrrh, frankincense, scorpion, borneol, earthworm, zaocys dhumnade, long-noded pit viper, ground beeltle, leech, scorpion and centipede as raw materials in proper weight proportion so that the raw materials are mutually matched and jointly acted, has good effects of resisting inflammation, relieving pain, dispelling pathogenic wind, removing dampness, promoting blood circulation, removing blood stasis, relieving swelling, promoting granulation, calming endogenous wind, relieving spasm, dredging meridian passage, strengthening tendons, and invigorating kidney, the traditional Chinese medicine composition has quick response and high cure rate when being used for treating various arthralgia and myalgia such as cervical vertebra and lumbar vertebra joints and the like, and relapse is not easy to occur after healing.
The preparation method of the external paste for treating arthralgia and myalgia, disclosed by the invention, comprises the following steps: (1) the equipment cost is low, the social benefit is large, the popularization is easy to master, and the device can be miniaturized; (2) the required medicinal materials can be fully utilized, no residue is left, the energy is saved, the environment is protected, pure traditional Chinese medicines are not added, the medicinal materials do not need to be leached, the production period is obviously shortened, the production cost is reduced, and the preparation method has obvious competitive advantage and wide application prospect; (3) saves cost and reduces labor, has high drug effect and less toxic and side effects, and is suitable for popularization and application.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be described in detail below. It is to be understood that the described embodiments are merely a few embodiments of the invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the examples given herein without making any creative effort, shall fall within the protection scope of the present invention. In the following examples, 1 part by weight represents 1 g.
Example 1
The embodiment provides a traditional Chinese medicine composition for treating arthralgia and myalgia, which comprises the following raw material components:
2 parts of obscured homalomena rhizome, 2 parts of tripterygium wilfordii, 1 part of pubescent angelica root, 1 part of notopterygium root, 1 part of corydalis tuber, 1 part of safflower, 1 part of garden balsam stem, 0.5 part of drynaria rhizome, 0.5 part of beautiful sweetgum fruit, 0.5 part of asarum, 0.5 part of cibotium rhizome, 0.5 part of yam rhizome, 0.5 part of szechuan lovage rhizome, 0.5 part of angelica, 0.5 part of suberect spatholobus stem, 0.5 part of common clubmoss herb, 0.3 part of mulberry twig, 0.3 part of dahurian angelica root, 0.3 part of peach kernel, 0.3 part of himalayan teasel root, 0.3 part of large-leaved gentian, 0.3 part of eucommia bark, 0.3 part of red paeony root, 0.3 part of argy wormwood leaf, 0.3 part of twotooth achyranthes root, 0.3 part of Chinese taxillus twig, 0.3 part of costustoot, 0.3 part of pine node, 0.3 part of pawpaw, 0.3 part of liquorice, 0.5 part of black-bone, 0.5 part of scorpion, 0.5 part of black snake, 0.5 part of bloody snake, 0.5 part of black snake, 0.2.5 part of black snake, and borneol, 0.1 part of long-noded pit viper, 0.1 part of ground beetle, 0.1 part of leech, 0.1 part of scorpion and 0.1 part of centipede.
Example 2
The embodiment provides a traditional Chinese medicine composition for treating arthralgia and myalgia, which comprises the following raw material components:
8 parts of obscured homalomena rhizome, 8 parts of tripterygium wilfordii, 5 parts of pubescent angelica root, 5 parts of incised notopterygium rhizome, 5 parts of corydalis tuber, 5 parts of safflower, 5 parts of garden balsam stem, 5 parts of drynaria rhizome, 5 parts of beautiful sweetgum fruit, 5 parts of asarum, 5 parts of east Asian tree fern rhizome, 5 parts of yam rhizome, 5 parts of szechuan lovage rhizome, 5 parts of Chinese angelica, 5 parts of suberect spatholobus stem, 5 parts of common clubmoss herb, 3 parts of mulberry twig, 3 parts of dahurian angelica root, 3 parts of peach kernel, 3 parts of himalayan teasel root, 3 parts of large-leaved gentian root, 3 parts of eucommia bark, 3 parts of red paeony root, 3 parts of Chinese mugwort leaf, 3 parts of twotooth achyranthes root, 3 parts of Chinese taxillus twig, 3 parts of costustoot, 3 parts of pine nodular branch, 3 parts of common floweringquince fruit, 3 parts of liquorice root, 5 parts of myrrh, 5 parts of frankincense, 5 parts of bloody scorpion, 5 parts of borneol, 2 parts of earthworm, 2 parts of black snake, 2 parts of black-tail snake, black-bone and the like snake, 1 part of long-noded pit viper, 1 part of ground beetle, 1 part of leech, 1 part of scorpion and 1 part of centipede.
Example 3
The embodiment provides a traditional Chinese medicine composition for treating arthralgia and myalgia, which comprises the following raw material components:
3 parts of obscured homalomena rhizome, 3 parts of tripterygium wilfordii, 2 parts of pubescent angelica root, 2 parts of incised notopterygium rhizome, 2 parts of corydalis tuber, 2 parts of safflower, 2 parts of garden balsam stem, 1 part of drynaria rhizome, 1 part of beautiful sweetgum fruit, 1 part of asarum, 1 part of east Asian tree fern rhizome, 1 part of rhizome of common yam rhizome, 1 part of szechuan lovage rhizome, 1 part of Chinese angelica, 1 part of suberect spatholobus stem, 1 part of common clubmoss herb, 0.5 part of mulberry twig, 0.5 part of dahurian angelica root, 0.5 part of peach kernel, 0.5 part of himalayan teasel root, 0.5 part of large-leaved gentian, 0.5 part of eucommia bark, 0.5 part of red paeony root, 0.5 part of Chinese mugwort leaf, 0.5 part of twotooth achyranthes root, 0.5 part of Chinese taxillus twig, 0.5 part of costus root, 0.5 part of nodular branch of pine needle, 0.5 part of common floweringquince fruit, 0.5 part of licorice root, 1 part of myrrh, 1 part of frankincense, 1 part of borneol, 1 part of scorpion, 0.5 part of black-tail snake and snake, 0.3 part of long-noded pit viper, 0.3 part of ground beetle, 0.3 part of leech, 0.3 part of scorpion and 0.3 part of centipede.
Example 4
The embodiment provides a traditional Chinese medicine composition for treating arthralgia and myalgia, which comprises the following raw material components:
5 parts of obscured homalomena rhizome, 5 parts of tripterygium wilfordii, 4 parts of pubescent angelica root, 4 parts of incised notopterygium rhizome, 4 parts of corydalis tuber, 4 parts of safflower, 4 parts of garden balsam stem, 3 parts of drynaria rhizome, 3 parts of beautiful sweetgum fruit, 3 parts of asarum, 3 parts of east Asian tree fern rhizome, 3 parts of rhizome of yam, 3 parts of szechuan lovage rhizome, 3 parts of angelica, 3 parts of suberect spatholobus stem, 3 parts of lycopodium clavatum, 1.5 parts of mulberry twig, 1.5 parts of dahurian angelica root, 1.5 parts of peach kernel, 1.5 parts of himalayan teasel root, 1.5 parts of large-leaved gentian, 1.5 parts of eucommia bark, 1.5 parts of red paeony root, 1.5 parts of Chinese mugwort leaf, 1.5 parts of twotooth achyranthes root, 1.5 parts of Chinese taxillus twig, 1.5 parts of costus root, 1.5 parts of pine knot, 1.5 parts of pawpaw, 1.5 parts of liquorice, 3 parts of myrrh, 3 parts of frankincense, 3 parts of borneol, 3 parts of scorpion, 1.5 parts of black snake and snake tip, 0.8 part of long-noded pit viper, 0.8 part of ground beetle, 0.8 part of leech, 0.8 part of scorpion and 0.8 part of centipede.
Example 5
The embodiment provides a traditional Chinese medicine composition for treating arthralgia and myalgia, which comprises the following raw material components:
4 parts of homalomena rhizoma, 4 parts of tripterygium wilfordii, 3 parts of pubescent angelica root, 3 parts of notopterygium root, 3 parts of corydalis tuber, 3 parts of safflower, 3 parts of garden balsam stem, 2 parts of drynaria rhizome, 2 parts of beautiful sweetgum fruit, 2 parts of asarum, 2 parts of east Asian tree fern rhizome, 2 parts of rhizome of yam, 2 parts of szechuan lovage, 2 parts of angelica, 2 parts of suberect spatholobus stem, 2 parts of common clubmoss herb, 1 part of mulberry twig, 1 part of dahurian angelica root, 1 part of peach kernel, 1 part of himalayan teasel root, 1 part of large-leaved gentian, 1 part of eucommia bark, 1 part of red paeony root, 1 part of argy leaf, 1 part of twotooth achyranthes root, 1 part of Chinese taxillus twig, 1 part of costustoot, 1 part of pine nodular branch, 1 part of common floweringquince fruit, 1 part of licorice root, 2 parts of myrrh, 2 parts of frankincense, 2 parts of bloody scorpion, 2 parts of borneol, 1 part of earthworm, 1 part of black snake, 1 part of black-tail snake, black-bone and black-bone, 0.5 part of long-noded pit viper, 0.5 part of ground beetle, 0.5 part of leech, 0.5 part of scorpion and 0.5 part of centipede.
Example 6
The embodiment provides an external ointment taking the traditional Chinese medicine composition in the embodiment 5 as a medicinal active ingredient, and the preparation method comprises the following steps:
(1) weighing the traditional Chinese medicine raw materials respectively, and drying and crushing the raw materials respectively to obtain raw material fine powder with the particle size of 100 meshes; uniformly mixing the fine powder of each raw material to obtain mixed medicinal powder;
(2) adding 60 ° Chinese liquor into the mixed medicinal powder, stirring, standing under sealed condition for 7 days, adding molten vaseline, and stirring to obtain paste (mixed medicinal powder: Chinese liquor: vaseline: 2:1: 0.3).
Example 7
The embodiment provides an external ointment taking the traditional Chinese medicine composition in the embodiment 4 as a medicinal active ingredient, and the preparation method comprises the following steps:
(1) weighing the traditional Chinese medicine raw materials respectively, and drying and crushing the raw materials respectively to obtain fine powder of the raw materials with the particle size of 80 meshes; uniformly mixing the fine powder of each raw material to obtain mixed medicinal powder;
(2) adding 60 ° Chinese liquor into the mixed medicinal powder, stirring, standing under sealed condition for 5 days, adding molten vaseline, and stirring to obtain paste (mixed medicinal powder: Chinese liquor: vaseline: 1.5:1: 0.3).
Example 8
The embodiment provides an external ointment taking the traditional Chinese medicine composition in the embodiment 3 as a medicinal active ingredient, and the preparation method comprises the following steps:
(1) weighing the traditional Chinese medicine raw materials respectively, and drying and crushing the raw materials respectively to obtain raw material fine powder with the particle size of 120 meshes; uniformly mixing the fine powder of each raw material to obtain mixed medicinal powder;
(2) adding 60 ° Chinese liquor into the mixed medicinal powder, stirring, standing under sealed condition for 9 days, adding molten vaseline, and stirring to obtain paste (mixed medicinal powder: Chinese liquor: vaseline: 2.5:1: 0.3).
Comparative example
The difference from the embodiment 6 lies in that yam rhizome in the traditional Chinese medicine composition is removed, and specifically, the traditional Chinese medicine composition of the comparative example comprises the following raw material components: 4 parts of homalomena rhizoma, 4 parts of tripterygium wilfordii, 3 parts of pubescent angelica root, 3 parts of notopterygium root, 3 parts of corydalis tuber, 3 parts of safflower, 3 parts of garden balsam stem, 2 parts of drynaria rhizome, 2 parts of beautiful sweetgum fruit, 2 parts of asarum, 2 parts of east Asian tree fern rhizome, 2 parts of szechuan lovage rhizome, 2 parts of Chinese angelica, 2 parts of suberect spatholobus stem, 2 parts of common clubmoss herb, 3 parts of mulberry twig, 1 part of dahurian angelica root, 1 part of peach seed, 1 part of himalayan teasel root, 1 part of large-leaved gentian, 1 part of eucommia bark, 1 part of red paeony root, 1 part of argy wormwood leaf, 1 part of twotooth achyranthes root, 1 part of Chinese taxillus twig, 1 part of costustoot, 1 part of pine knot, 1 part of common floweringquince fruit, 1 part of liquoric root, 2 parts of myrrh, 2 parts of frankincense, 2 parts of sanguine scorpion, 2 parts of borneol, 1 part of earthworm, 1 part of black-tail snake, 0.5 part of long-noded pit viper, long-headed snake, and their preparation, 0.5 part of ground beetle, 0.5 part of leech, 0.5 part of scorpion and 0.5 part of centipede.
Clinical Total therapeutic Effect test study of the invention
1. The general data selects 208 patients with bone joint pain, and randomly divides the patients into 106 experimental groups, including 50 men, 56 women and age between 55 and 70 years, wherein 12 patients with cervical vertebra pain, 48 patients with lumbar vertebra pain and 46 patients with knee joint pain; the control group 1 comprises 52 cases including 24 cases of men and 28 cases of women, the age is 53-65 years old, wherein 6 cases of cervical vertebra pain, 24 cases of lumbar vertebra pain and 22 cases of knee joint pain; the control group 2 comprises 50 cases including 23 men and 27 women, and the age is 55-70 years old, wherein 6 cases of cervical vertebra pain, 22 cases of lumbar vertebra pain and 22 cases of knee joint pain.
2. Treatment method the test group and the control 1 group were administered with the analgesic topical ointment of the present invention (the ointment was taken in an appropriate amount and filled into a medical ointment patch and applied to the affected part, one patch per day), and the control 2 group was administered with the musk rheumatalgia-relieving ointment, one patch per day, and each group was treated continuously for 7 days.
3. The curative effect standard is cured: the local pain completely disappears, and the motor function returns to normal; the effect is shown: the local pain is obviously relieved, the swelling disappears, and the motion function is basically recovered; the method has the following advantages: the local pain is relieved, the swelling is reduced, and the motion function is limited; and (4) invalidation: the symptoms are as before.
4. The therapeutic effect is shown in table 1.
TABLE 1 Total treatment Effect statistics
The results show that the total effective rates of the test group, the control group 1 and the control group 2 are 100%, 92.31% and 82.00% respectively, the test group is obviously better than the other groups, namely, the plaster adopting the traditional Chinese medicine composition of the embodiment 5 has obviously better treatment effect than the plaster adopting the traditional Chinese medicine composition of the embodiment 5 without yam rhizome, and has prominent advantages compared with the commercially available products, which shows that the raw materials of the embodiment 5 of the invention have scientific compatibility and reasonable proportion, can obviously relieve the pain of patients suffering from osteoarticular pain, and has the characteristics of quick response and obvious curative effect.
The traditional Chinese medicine composition can effectively relieve bone and joint pain, has a good treatment effect on pain caused by traumatic injury and the like, and is shown in a table 2 as a representative specific case.
TABLE 2 typical treatment cases
The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.