CN114681353A - 一种适用于婴幼儿的皮肤止痒舒缓液及其制备方法 - Google Patents
一种适用于婴幼儿的皮肤止痒舒缓液及其制备方法 Download PDFInfo
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Abstract
本发明涉及护肤品技术领域,涉及一种适用于婴幼儿的皮肤止痒舒缓液,用于解决现有止痒舒缓液止痒消肿效果不佳,对皮肤有刺激性,涂抹后不能修护蚊虫叮咬痕肌的问题;本发明提供一种适用于婴幼儿的皮肤止痒舒缓液,以水、丙二醇、甘草根提取物、龙胆根提取物、苦参根提取物、蛇床果提取物、青蒿提取物组成的止痒缓释物,丁二醇、糖鞘脂类组成的保湿剂,水、丙二醇、壬基酚聚醚‑14、PEG‑50蓖麻油组成的表面活性剂,再加入其他添加剂制备的止痒舒缓液;本发明止痒缓释物采用纯天然植物提取物,安全无副作用,适合婴幼儿使用及其它肌肤较为脆弱的人群使用,且本发明皮肤止痒舒缓液不仅可用于预防蚊虫叮咬还也可用于蚊虫叮咬后的止痒修复。
Description
技术领域
本发明涉及护肤品技术领域,更具体地,涉及一种适用于婴幼儿的皮肤止痒舒缓液及其制备方法。
背景技术
婴幼儿皮肤的特点是皮肤免疫能力低、敏感脆弱,属于皮肤免疫力波动阶段。该阶段婴幼儿皮肤特征的突出表现为皮肤抑菌能力的变化,母体先天带来的免疫力已逐渐减弱,婴幼儿自身免疫仍处萌芽阶段,皮肤的免疫力低。婴幼儿新陈代谢快,更容易受到蚊虫的叮咬,由此导致被叮咬处发痒、起包、发红。
目前市场上有很多舒缓止痒的产品,但大部分产品采用化学原料提炼而成,含有大量对人体有害的物质,安全性无法保障,特别是对于婴幼儿来说,很容易引起其它健康问题。并且,在产品使用期间,不能起到快速杀菌止痒的效果,还可能出现过敏、红肿等现象。
发明内容
本发明旨在克服上述现有技术的至少一种缺陷(不足),提供一种适用于婴幼儿的皮肤止痒舒缓液及其制备方法,达到杀菌止痒、抗炎消肿、淡化叮包、修护痕肌的效果,且产品采用纯天然植物提取,安全无刺激,特别适合婴幼儿使用。
本发明采取的技术方案是,一种适用于婴幼儿的皮肤止痒舒缓液,包括如下组分,按重量份计:
A组分:
B组分:
本发明提供一种适用于婴幼儿的皮肤止痒舒缓液,海藻糖能在表皮细胞上形成保护屏障,保持细胞活力,甘油能加快皮肤的愈合,减少炎症发生,使皮肤恢复正常屏障功能,海藻糖与甘油协同作用,加快受损皮肤愈合,恢复屏障功能;尿囊素与芦荟提取物具备一定的杀菌止痒及消炎作用,防止皮肤感染;樟脑能够驱虫,避免被蚊虫叮咬;止痒缓释物包括多种纯天然提取的有效成分复配,具有广谱抗菌性,能杀虫止痒、抗炎消肿的效果。采用如上述的适用于婴幼儿的皮肤止痒舒缓液,可用于预防蚊虫叮咬,或用于被蚊虫叮咬后快速消炎消肿、杀菌止痒、淡化叮包及修护痕肌等。
进一步地,C组分中所述止痒缓释物由水、丙二醇、甘草根提取物、龙胆根提取物、苦参根提取物、蛇床果提取物、青蒿提取物按35:60:1:1:1:1:1配制而成。
水、丙二醇作为溶剂,有利于甘草根提取物、龙胆根提取物、苦参根提取物、蛇床果提取物、青蒿提取物等溶解度;甘草根提取物作为一种抗炎剂,安全系数高,适用于皮肤较为脆弱的人群,特别适合于婴幼儿使用;龙胆根提取物为龙胆科植物龙胆的根及极茎提取的苦龙胆脂甙龙胆苦苷,具有较好的止痒消肿效果;苦参提取物具有杀虫的功效,对皮肤瘙痒有很好的缓解作用,并且促进受损血管神经细胞的生长和修复,恢复皮下毛细血管细胞活力;蛇果提取物作为一种安全系数高的抗菌剂,与上述其它成分复配使用,相互促进,能快速有效地起到抗菌消炎止痒的效果。
进一步地,C组分中所述保湿剂由丁二醇、糖鞘脂类按11:1配制而成。
丁二醇作为常见的溶剂保湿剂使用,糖鞘脂类能够有效改善角质细胞的粘合力,使细胞紧密结合,降低水分丧失,丁二醇与糖鞘脂类的组合物作为保湿剂使用,能有效减缓止痒舒缓液的挥发,延长其作用效果。
进一步地,D组分中所述表面活性剂由水、丙二醇、壬基酚聚醚-14、PEG-50蓖麻油按6:5:5:4配制而成。
优先地,包括如下组分,按重量份计:
A组分:
B组分:
一种如上任一所述的适用于婴幼儿的皮肤止痒舒缓液的制备方法,将A组分充分溶解后,加入B、C组分,搅拌使充分混合,再加入预先处理溶解充分的D组分,搅拌至混合均匀,抽样检测合格后,过滤出料,储存。
进一步地,具体包括如下步骤:
S1:将A组分物料加热至80℃之后,充分溶解;
S2:待搅拌至完全溶解,降温至60℃,加入B、C组分;
S3:将D组分物料预先处理,加热至80℃使其完全溶解,降温至40℃,将D组分加入S2的混合组分中,完成组分混合;
S4:将步骤S3中的混合组分降温至35℃以下,抽样检测合格后,过滤出料,得到舒缓液。
与现有技术相比,本发明的有益效果为:
1)止痒缓释物采用纯天然植物提取物,安全无副作用,适合婴幼儿使用及其它肌肤较为脆弱的人群使用;
2)本发明的皮肤止痒舒缓液可用于预防蚊虫叮咬也可用于蚊虫叮咬后的止痒修复。
具体实施方式
本发明实施例仅用于示例性说明,不能理解为对本发明的限制。
实施例1
一种适用于婴幼儿的皮肤止痒舒缓液,包括如下组分,按重量份计:
A组分:
B组分:
实施例2
一种适用于婴幼儿的皮肤止痒舒缓液,包括如下组分,按重量份计:
A组分:
B组分:
1,2-己二醇 0.5份;
对羟基苯乙酮 0.5份;
C组分:
止痒缓释物 0.4份;
保湿剂 0.1份;
D组份:
其中,止痒缓释物为:
其中,保湿剂为:
丁二醇 0.095份;
糖鞘脂类 0.005份;
其中,表面活性剂为:
实施例3
一种适用于婴幼儿的皮肤止痒舒缓液,包括如下组分,按重量份计:
A组分:
B组分:
1,2-己二醇 0.5份;
对羟基苯乙酮 0.5份;
C组分:
止痒缓释物 0.6份;
保湿剂 0.2份;
D组份:
其中,止痒缓释物为:
其中,保湿剂为:
丁二醇0.19份;
糖鞘脂类0.1份;
其中,表面活性剂为:
试验一:
选择30只新生小白鼠,分成5组做好标记,其中三组作为试验组,分别用实施例1、实施例2、实施例3的制成的止痒舒缓液涂抹,对照组用普通花露水涂抹,空白组不做任何处理。
将30只新生小白鼠放置在有蚊虫的实验环境下,一小时后观察表皮上叮包、红肿等情况。实验发现,空白组的小白鼠表皮上的叮包、红肿数量最多,对照组的叮包、红肿数量相对少一些,但部分小白鼠还出现了过敏现象,试验组的叮包、红肿数量最少,且没有出现过敏现象。
试验二:
将20只新生小白鼠放置在有蚊虫的实验环境下,当小白鼠表皮上有较多叮包、红肿等情况时,分成4组,其中三组作为试验组,分别用实施例1、实施例2及实施例3制备的止痒舒缓液涂抹,另一组作为对照组,用普通花露水涂抹,待1小时、2小时后分别观察各组小白鼠表皮上叮包、红肿情况。实验发现1小时后,试验组的小白鼠叮包、红肿大部分消退,没有出现其他过敏象,但仍有被叮咬的痕迹;对照组的小白鼠叮包、红肿部分消退,叮咬痕迹明显且部分小白鼠出现了过敏现象;2小时后,试验组的小白鼠叮包、红肿基本消退,且表皮上大部分已看不出被叮咬的痕迹;而对照组的小白鼠叮包、红肿仍有较多未消退情况,且部分消退的叮包、红肿处仍存在被叮咬的痕迹。
由此可知,本发明的皮肤止痒舒缓液无论对于预防蚊虫叮咬或对于被蚊虫叮咬后的止痒水肿均具有较好的效果,对于皮肤不会产生任何刺激,安全无副作用,且本发明的皮肤止痒舒缓液还具有修复痕肌的效果。
显然,本发明的上述实施例仅仅是为清楚地说明本发明技术方案所作的举例,而并非是对本发明的具体实施方式的限定。凡在本发明权利要求书的精神和原则之内所作的任何修改、等同替换和改进等,均应包含在本发明权利要求的保护范围之内。
Claims (7)
2.根据权利要求1所述的一种适用于婴幼儿的皮肤止痒舒缓液,其特征在于,C组分中所述止痒缓释物由水、丙二醇、甘草根提取物、龙胆根提取物、苦参根提取物、蛇床果提取物、青蒿提取物按35:60:1:1:1:1:1配制而成。
3.根据权利要求1所述的一种适用于婴幼儿的皮肤止痒舒缓液,其特征在于,C组分中所述保湿剂由丁二醇、糖鞘脂类按11:1配制而成。
4.根据权利要求1所述的一种适用于婴幼儿的皮肤止痒舒缓液,其特征在于,D组分中所述表面活性剂由水、丙二醇、壬基酚聚醚-14、PEG-50蓖麻油按6:5:5:4配制而成。
6.一种如权利要求1-5任一所述的适用于婴幼儿的皮肤止痒舒缓液的制备方法,其特征在于,将A组分充分溶解后,加入B、C组分,搅拌使充分混合,再加入预先处理溶解充分的D组分,搅拌至混合均匀,抽样检测合格后,过滤出料,储存。
7.根据权利要求6所述的适用于婴幼儿的皮肤止痒舒缓液的制备方法,其特征在于,具体包括如下步骤:
S1:将A组分物料加热至80℃之后,充分溶解;
S2:待搅拌至完全溶解,降温至60℃,加入B、C组分;
S3:将D组分物料预先处理,加热至80℃使其完全溶解,降温至40℃,将D组分加入S2的混合组分中,完成组分混合;
S4:将步骤S3中的混合组分降温至35℃以下,抽样检测合格后,过滤出料,得到舒缓液。
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