CN114652658A - Traditional Chinese medicine extract composition and application thereof, traditional Chinese medicine extract gel no-clean facial mask and preparation method thereof - Google Patents
Traditional Chinese medicine extract composition and application thereof, traditional Chinese medicine extract gel no-clean facial mask and preparation method thereof Download PDFInfo
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- CN114652658A CN114652658A CN202210490591.XA CN202210490591A CN114652658A CN 114652658 A CN114652658 A CN 114652658A CN 202210490591 A CN202210490591 A CN 202210490591A CN 114652658 A CN114652658 A CN 114652658A
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/042—Gels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/82—Preparation or application process involves sonication or ultrasonication
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Mycology (AREA)
- Dermatology (AREA)
- Microbiology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention belongs to the technical field of cosmetic preparation, and particularly relates to a traditional Chinese medicine extract composition and application thereof, a traditional Chinese medicine extract gel no-clean facial mask and a preparation method thereof. The invention provides a traditional Chinese medicine extract composition which comprises the following components in parts by mass: 0.5-2.5 parts of sweet wormwood herb water extract, 0.6-2.6 parts of aloe extract, 0.8-3.1 parts of liquorice water extract, 0.4-2.8 parts of coix seed extract, 0.1-4 parts of radix angelicae water extract and 1-2 parts of poria alba extract. According to the invention, the six traditional Chinese medicine extracts can be used as active ingredients of cosmetics under the compounding condition of the above weight parts, and have moisturizing and anti-aging effects.
Description
Technical Field
The invention belongs to the technical field of cosmetic preparation, and particularly relates to a traditional Chinese medicine extract composition and application thereof, a traditional Chinese medicine extract gel no-clean facial mask and a preparation method thereof.
Background
With the increasing environmental pollution and the increasing working pressure of people, the skin problems which become more serious are widely existed. Meanwhile, with the continuous improvement of modern living standard, more consumers begin to pay attention to skin care. In the daily use of skin care products, the mask product is in the prostate. The facial mask is used as a carrier of a beauty care product, and is applied on face for beauty functions, such as moisturizing, whitening, anti-aging, balancing oil and fat, and the like.
The night is the gold time for skin restoration and regeneration, and the patch type mask is not convenient to use at night, so the wash-free mask can be produced. Most of the active ingredients of the no-clean facial masks in the market are chemically synthesized ingredients, so that the no-clean facial masks bring certain effects to the skin and are easy to cause problems such as dependence, side effects and the like, for example, allergy, gradient decrease of skin care effect, pigmentation and the like.
Chinese herbal medicine resources are rich, the theory of traditional Chinese medicine is deep and has a long history, the application of the traditional Chinese herbal medicine extract to skin care products by virtue of natural characteristics becomes a hot point of research of people, and facial masks with traditional Chinese medicine formulas begin to appear on the market, but the traditional Chinese medicine facial masks have some defects. For example, the existing pure traditional Chinese medicine facial mask in the market has single effect and poor moisturizing and nourishing effects, and is difficult to improve the skin.
Disclosure of Invention
In view of the above, the invention provides a traditional Chinese medicine extract composition and application thereof, a traditional Chinese medicine extract gel no-wash mask and a preparation method thereof. The traditional Chinese medicine extract gel no-clean facial mask provided by the invention has the double effects of water retention, moisture retention and oxidation resistance, and can effectively improve the skin quality.
In order to solve the technical problems, the invention provides a traditional Chinese medicine extract composition which comprises the following components in parts by mass:
0.5-2.5 parts of sweet wormwood herb water extract, 0.6-2.6 parts of aloe extract, 0.8-3.1 parts of liquorice water extract, 0.4-2.8 parts of coix seed extract, 0.1-4 parts of radix angelicae water extract and 1-2 parts of poria alba extract.
Preferably, the preparation method of the sweet wormwood herb aqueous extract comprises the following steps:
ultrasonically mixing sweet wormwood powder and water to obtain sweet wormwood mixed solution;
heating and extracting the sweet wormwood mixed solution to obtain the sweet wormwood aqueous extract;
the mass ratio of the sweet wormwood powder to the volume of water is 1g:10 mL; the temperature of the heating extraction is 35 ℃, the heat preservation time of the heating extraction is 8h, and the times of the heating extraction are 2.
Preferably, the preparation method of the aloe extract comprises the following steps:
mixing aloe powder with ethanol-water mixed solvent to obtain aloe mixed solution;
heating and extracting the aloe mixed solution to obtain the aloe extract;
the material-liquid ratio of the aloe mixed liquid is 1: 10; the temperature of the heating extraction is 60 ℃, the heat preservation time of the heating extraction is 60min, the times of the heating extraction are 2 times, and the volume content of the ethanol in the ethanol-water mixed solvent is 50%.
Preferably, the preparation method of the licorice aqueous extract comprises the following steps:
mixing the liquorice powder with a mixed solvent of water to obtain a liquorice mixed solution;
heating and extracting the licorice mixed solution to obtain the licorice aqueous extract;
the material-liquid ratio of the liquorice mixed liquor is 1: 10; the temperature of the heating extraction is 95 ℃, the heat preservation time of the heating extraction is 2min, and the times of the heating extraction are 2 times.
Preferably, the preparation method of the coix seed extract comprises the following steps:
mixing the coix seed powder with a mixed solvent of ethanol and water to obtain coix seed mixed solution;
heating and extracting the coix seed mixed solution to obtain the coix seed extract;
the material-liquid ratio of the coix seed mixed liquid is 1: 8; the temperature of the heating extraction is 65 ℃, the heat preservation time of the heating extraction is 120min, and the volume content of the ethanol in the ethanol-water mixed solvent is 90%.
Preferably, the preparation method of the radix angelicae aqueous extract comprises the following steps:
ultrasonically mixing the angelica dahurica powder with water to obtain an angelica dahurica mixed solution;
heating and extracting the radix angelicae mixed solution to obtain the radix angelicae water extract;
the ratio of the mass of the angelica dahurica powder to the volume of the water is 1g:10 mL; the temperature of the heating extraction is 35 ℃, and the heat preservation time of the heating extraction is 8 h.
Preferably, the preparation method of the poria cocos wolf extract comprises the following steps:
mixing the white poria powder with an ethanol-water mixed solvent to obtain a white poria mixed solution;
ultrasonically extracting the white poria mixed solution to obtain the white poria extract;
the mass ratio of the white poria cocos powder to the volume of water is 1g:10 mL; the temperature of the ultrasonic extraction is 25 ℃, the heat preservation time of the ultrasonic extraction is 200min, and the ultrasonic frequency of the ultrasonic extraction is 200 Hz; the volume content of ethanol in the ethanol-water mixed solvent is 70%.
The invention provides application of the traditional Chinese medicine composition in cosmetics.
The invention provides a traditional Chinese medicine extract gel no-clean mask which comprises the following components in parts by mass:
3-15 parts of an active component of a composite traditional Chinese medicine extract, 0.6-1.5 parts of a penetrating agent, 1.5-3 parts of a gel matrix, 12-30 parts of glycerol, 0.6 part of an odor regulator, 0.15 part of an emulsifier, 0.3 part of a preservative and 230-285 parts of water; the active component of the compound traditional Chinese medicine extract is the traditional Chinese medicine extract composition of any one of claims 1-7.
The invention provides a preparation method of a traditional Chinese medicine extract gel wash-free mask, which comprises the following steps:
mixing the active components of the compound Chinese medicinal extract, penetrant, glycerin, odor regulator, preservative and water to obtain water phase;
and mixing the water phase, the emulsifier and the gel matrix to obtain the traditional Chinese medicine extract gel no-clean facial mask.
The invention provides a traditional Chinese medicine extract composition which comprises the following components in parts by mass: 0.5-2.5 parts of sweet wormwood herb water extract, 0.6-2.6 parts of aloe extract, 0.8-3.1 parts of liquorice water extract, 0.4-2.8 parts of coix seed extract, 0.1-4 parts of radix angelicae water extract and 1-2 parts of poria alba extract. The traditional Chinese medicine extract composition provided by the invention has the advantages that the sweet wormwood aqueous extract has obvious antibacterial and anti-inflammatory activities, and the skin immunocompetence is improved; the aloe extract not only has the effects of sterilizing and resisting inflammation, but also has the effects of beautifying and protecting skin, replenishing water and moisturizing; the Glycyrrhrizae radix water extract can improve pachylosis, water deficiency, and inflammation; the coix seed extract can accelerate blood circulation of skin, accelerate the transportation of nutrient substances and oxygen and make skin smooth; the radix angelicae aqueous extract can effectively inhibit phototoxicity; the poria cocos extract cheese has high inhibition rate on the ammonia enzyme and has better melanin deposition prevention effect. According to the invention, the six traditional Chinese medicine extracts can be used as active ingredients of cosmetics under the compounding condition of the above weight parts, and have moisturizing and anti-aging effects.
The invention provides a traditional Chinese medicine extract gel wash-free mask which comprises the following components in parts by mass: 3-15 parts of an active component of a composite traditional Chinese medicine extract, 0.6-1.5 parts of a penetrating agent, 1.5-3 parts of a gel matrix, 12-30 parts of glycerol, 0.6 part of an odor regulator, 0.15 part of an emulsifier, 0.3 part of a preservative and 230-285 parts of water; the active component of the composite traditional Chinese medicine extract is the traditional Chinese medicine extract composition in the technical scheme. According to the traditional Chinese medicine extract gel no-clean facial mask provided by the invention, the traditional Chinese medicine extract composition is used as a skin care active component of the facial mask and compounded with other functional components, and under the matching condition of the above parts by mass, the gel no-clean facial mask which has dual effects of moisturizing and anti-aging and is simple and convenient to use can be obtained.
Detailed Description
The invention provides a traditional Chinese medicine extract composition which comprises the following components in parts by mass:
0.5-2.5 parts of sweet wormwood aqueous extract, 0.6-2.6 parts of aloe extract, 0.8-3.1 parts of liquorice aqueous extract, 0.4-2.8 parts of coix seed extract, 0.1-4 parts of angelica dahurica aqueous extract and 1-2 parts of poria alba extract.
In the present invention, the preparation method of the aqueous artemisia apiacea extract preferably comprises the following steps:
ultrasonically mixing sweet wormwood powder and water to obtain sweet wormwood mixed solution;
heating and extracting the sweet wormwood mixed solution to obtain the sweet wormwood aqueous extract;
the mass ratio of the sweet wormwood powder to the volume of water is 1g:10 mL; the temperature of the heating extraction is 35 ℃, the heat preservation time of the heating extraction is 8h, and the times of the heating extraction are 2 times.
In a specific embodiment of the present invention, the preparation method of the sweet wormwood water extract specifically comprises the following steps:
pulverizing herba Artemisiae Annuae in pulverizer, sealing in plastic bag, and placing in cool and dry place. Weighing 50.0g of sweet wormwood powder in a 1L round bottom flask, adding 500.0mL of distilled water while stirring, performing ultrasonic treatment for 1h, heating in a water bath at 35 ℃ for extraction for 8h, filtering, centrifuging to obtain a supernatant, repeating twice, combining the solutions, concentrating to 50.0mL, and freeze-drying.
In the present invention, the preparation method of the aloe extract preferably includes the steps of:
mixing aloe powder with ethanol-water mixed solvent to obtain aloe mixed solution;
heating and extracting the aloe mixed solution to obtain the aloe extract;
the material-liquid ratio of the aloe mixed liquid is 1: 10; the temperature of the heating extraction is 60 ℃, the heat preservation time of the heating extraction is 60min, the times of the heating extraction are 2 times, and the volume content of ethanol in the ethanol-water mixed solvent is 50%.
In a specific embodiment of the present invention, the preparation method of the aloe extract specifically comprises the following steps:
pulverizing aloe into fine powder, weighing 50g of aloe fine powder, adding an ethanol-water mixed solution, placing the aloe fine powder and the ethanol-water mixed solution into a round-bottom flask at the ethanol-water mixed solution with the volume percentage of 50% of ethanol and the material-liquid ratio of 1:10, heating and refluxing in a water bath for 60min at the temperature of 60 ℃, repeating twice, combining supernatants, concentrating to 50mL, and freeze-drying.
In the present invention, the preparation method of the licorice aqueous extract preferably comprises the following steps:
mixing the liquorice powder with a mixed solvent of water to obtain a liquorice mixed solution;
heating and extracting the licorice mixed solution to obtain the licorice aqueous extract;
the material-liquid ratio of the liquorice mixed liquor is 1: 10; the temperature of the heating extraction is 95 ℃, the heat preservation time of the heating extraction is 2min, and the times of the heating extraction are 2 times.
In a specific embodiment of the present invention, the preparation method of the licorice aqueous extract specifically comprises the following steps:
pulverizing Glycyrrhrizae radix into fine powder, sieving with 60 mesh sieve to obtain Glycyrrhrizae radix fine powder, sealing in plastic bag, and placing in dry place. Weighing 50g of Glycyrrhrizae radix fine powder, adding 500g of water, extracting with water at 95 deg.C for 2 times, each time for 2 hr, centrifuging to obtain supernatant, concentrating under reduced pressure, and drying.
In the present invention, the preparation method of the coix seed extract preferably comprises the following steps:
mixing the coix seed powder with a mixed solvent of ethanol and water to obtain coix seed mixed solution;
heating and extracting the coix seed mixed solution to obtain the coix seed extract;
the material-liquid ratio of the coix seed mixed liquid is 1: 8; the temperature of the heating extraction is 65 ℃, the heat preservation time of the heating extraction is 120min, and the volume content of the ethanol in the ethanol-water mixed solvent is 90%.
In an embodiment of the present invention, the preparation method of the coix seed extract specifically comprises the following steps:
pulverizing Coicis semen decoction pieces, sieving with 60 mesh sieve to obtain Coicis semen powder, sealing in plastic bag, placing in cool and dry place, weighing 50g Coicis semen powder, adding ethanol-water mixed solution, wherein ethanol content of 90% by volume in the ethanol-water mixed solution, performing hot reflux extraction at 65 deg.C for 120min at a material-liquid ratio of 1:8, concentrating the filtrate, and drying.
In the present invention, the preparation method of the aqueous extract of radix angelicae preferably comprises the following steps:
ultrasonically mixing the angelica dahurica powder with water to obtain an angelica dahurica mixed solution;
heating and extracting the radix angelicae mixed solution to obtain the radix angelicae water extract;
the ratio of the mass of the angelica dahurica powder to the volume of the water is 1g:10 mL; the temperature of the heating extraction is 35 ℃, and the heat preservation time of the heating extraction is 8 h.
In a specific embodiment of the invention, the preparation method of the radix angelicae aqueous extract specifically comprises the following steps:
pulverizing radix Angelicae Dahuricae in pulverizer, sieving with 0.42mm (40 mesh) sieve, sealing in plastic bag, and placing in cool and dry place. Weighing 50.0g of radix angelicae dahuricae powder, adding into a 1L round-bottom flask, adding 500.0mL of distilled water under stirring, heating in a water bath at 35 ℃ for extraction for 8h, filtering, centrifuging, concentrating the supernatant to 50.0mL, and freeze-drying.
In the present invention, the preparation method of the poria cocos wolf extract preferably comprises the steps of:
mixing the white poria powder with a mixed solvent of ethanol and water to obtain a white poria mixed solution;
ultrasonically extracting the white poria mixed solution to obtain a white poria extract;
the mass ratio of the white poria cocos powder to the volume of water is 1g:10 mL; the temperature of the ultrasonic extraction is 25 ℃, the heat preservation time of the ultrasonic extraction is 200min, and the ultrasonic frequency of the ultrasonic extraction is 200 Hz; the volume content of ethanol in the ethanol-water mixed solvent is 70%.
In a specific embodiment of the present invention, the preparation method of the poria cocos wolf extract specifically comprises the following steps:
pulverizing Poria cocos (Schw.) wolf in a pulverizer, sieving with a 40-mesh sieve with a pore diameter of 0.42mm to obtain Poria cocos coarse powder, sealing in a plastic bag, placing in a cool and dry place for later use, weighing 50.0g Poria cocos coarse powder, adding 500.0mL of ethanol-water mixed solution, wherein ethanol is 70% by volume in the ethanol-water mixed solution, performing ultrasonic extraction at 25 ℃ for 20.0min, performing ultrasonic extraction at an ultrasonic frequency of 200Hz, filtering, repeating the above operation on filter residues for 2 times, combining filtrates, concentrating to 500mL, centrifuging to obtain a supernatant, concentrating under reduced pressure to 50.0mL, and freeze-drying.
In the present invention, the important extract composition preferably comprises the following components in parts by mass:
0.8-2 parts of sweet wormwood water extract, 0.8-2.5 parts of aloe extract, 0.9-3 parts of liquorice water extract, 0.5-2.5 parts of coix seed extract, 0.25-3.5 parts of radix angelicae water extract and 1-1.5 parts of poria alba extract.
In the present invention, the important extract composition more preferably comprises the following components in parts by mass:
1 part of sweet wormwood water extract, 1-2 parts of aloe extract, 1 part of liquorice water extract, 1 part of coix seed extract, 1-2 parts of radix angelicae water extract and 1-2 parts of poria alba extract.
In the present invention, the important extract composition most preferably comprises the following components in parts by mass:
1 part of sweet wormwood water extract, 2 parts of aloe extract, 1 part of liquorice water extract, 1 part of coix seed extract, 1 part of angelica dahurica water extract and 1 part of poria alba extract.
The invention provides application of the traditional Chinese medicine composition in cosmetics.
The invention provides a traditional Chinese medicine extract gel wash-free mask which comprises the following components in parts by mass:
3-15 parts of an active component of a composite traditional Chinese medicine extract, 0.6-1.5 parts of a penetrating agent, 1.5-3 parts of a gel matrix, 12-30 parts of glycerol, 0.6 part of an odor regulator, 0.15 part of an emulsifier, 0.3 part of a preservative and 230-285 parts of water; the active component of the compound traditional Chinese medicine extract is the traditional Chinese medicine extract composition of claim 1.
In the present invention, the starting materials are all commercially available products well known to those skilled in the art unless otherwise specified.
The traditional Chinese medicine extract gel no-clean facial mask comprises, by mass, 3-15 parts of a composite traditional Chinese medicine extract active component, and more preferably 3.5-15 parts.
Based on the mass parts of the active components of the compound traditional Chinese medicine extract, the traditional Chinese medicine extract gel no-clean facial mask provided by the invention comprises 0.6-1.5 parts of penetrating agent, and more preferably 0.75-1.5 parts.
In the present invention, the penetrant is preferably one or more of azone, isosorbide dimethyl ether, and thiaketone, and more preferably azone.
Based on the mass parts of the active components of the compound traditional Chinese medicine extract, the traditional Chinese medicine extract gel no-clean facial mask provided by the invention comprises 1.5-3 parts of gel matrix, and more preferably 2-3 parts.
In the present invention, the gel matrix is particularly preferably carbomer 940.
Based on the mass parts of the active components of the compound traditional Chinese medicine extract, the traditional Chinese medicine extract gel no-clean facial mask provided by the invention comprises 12-30 parts of glycerin, and more preferably 15-30 parts of glycerin.
Based on the mass parts of the active components of the compound traditional Chinese medicine extract, the traditional Chinese medicine extract gel no-clean facial mask provided by the invention comprises 0.6 part of odor regulator.
In the present invention, the odor regulator is preferably water lily essential oil and/or citrus essential oil.
Based on the mass parts of the active components of the compound traditional Chinese medicine extract, the traditional Chinese medicine extract gel no-clean facial mask provided by the invention comprises 0.15 parts of emulsifier.
In the present invention, the emulsifier is preferably one or more of sodium carboxymethylcellulose, tween-60 and tween-80, and more preferably sodium carboxymethylcellulose.
Based on the mass parts of the active components of the compound traditional Chinese medicine extract, the traditional Chinese medicine extract gel no-clean facial mask provided by the invention comprises 0.3 part of preservative.
In the present invention, the preservative is particularly preferably methylparaben.
Based on the mass parts of the active components of the compound traditional Chinese medicine extract, the traditional Chinese medicine extract gel no-clean facial mask provided by the invention comprises 230-285 parts of water, and more preferably 235-270 parts of water.
In the present invention, the water is preferably deionized water.
The traditional Chinese medicine extract gel no-clean mask provided by the invention preferably further comprises a pH regulator.
In the present invention, the pH adjuster is specifically triethanolamine.
In the invention, the dosage of the pH regulator is preferably the dosage of regulating the pH value of the traditional Chinese medicine extract gel no-clean facial mask to 7-7.2.
The traditional Chinese medicine extract gel no-clean mask provided by the invention preferably comprises the following components in parts by mass:
15 parts of active component of the compound traditional Chinese medicine extract, 1.5 parts of penetrating agent, 3 parts of gel matrix, 30 parts of glycerin, 0.6 part of odor regulator, 0.15 part of emulsifier, 0.3 part of preservative and 249.5 parts of water.
In the invention, the pH value of the traditional Chinese medicine extract gel no-clean mask is preferably 7-7.2.
The invention provides a preparation method of a traditional Chinese medicine extract gel wash-free mask, which comprises the following steps:
mixing the active components of the compound Chinese medicinal extract, penetrant, glycerin, odor regulator, preservative and water; obtaining a water phase;
mixing the water phase, the mixer and the gel matrix to obtain the traditional Chinese medicine extract gel no-clean facial mask.
The invention mixes the active components of the compound traditional Chinese medicine extract, the penetrating agent, the glycerin, the odor regulator, the preservative and the water (hereinafter referred to as first mixing); an aqueous phase is obtained.
In the present invention, the first mixing preferably includes the steps of:
heating the water to a first temperature and then carrying out first heat preservation;
sequentially adding the active component of the compound traditional Chinese medicine extract, the preservative, the glycerol, the odor regulator and the penetrating agent into water heated to a first temperature, and mixing and dissolving to obtain a premix;
and sterilizing the premix, and cooling to a second temperature to obtain the water phase.
In the invention, the first temperature is preferably 65-75 ℃, and the first heat preservation time is preferably 20-30 min.
In the invention, the mixing and dissolving are preferably carried out under the price adjustment of stirring, and the invention has no special requirement on the specific implementation process of the stirring.
In the present invention, the second temperature is preferably 35 to 40 ℃.
The invention has no special requirements for the specific implementation process of the sterilization.
After obtaining the aqueous phase, the present invention mixes the aqueous phase, the mixer and the gel matrix (hereinafter, referred to as second mixing) to obtain the traditional Chinese medicine extract gel leave-on mask.
In the invention, before the second mixing, the pH value of the water phase is preferably adjusted to 7-7.2 by using the pH regulator.
The invention has no special requirements on the specific implementation process of the second mixing.
In the invention, the second mixing is carried out to obtain a second mixed solution, and the invention preferably stands the second mixed solution until the second mixed solution is completely swelled to obtain the traditional Chinese medicine extract gel no-clean facial mask.
In order to further illustrate the present invention, the following embodiments are described in detail, but they should not be construed as limiting the scope of the present invention.
Example 1
Pulverizing herba Artemisiae Annuae in pulverizer, sealing in plastic bag, and placing in cool and dry place. Weighing 50.0 herba Artemisiae Annuae powder in a 1L round bottom flask, adding 500.0mL of distilled water under stirring, performing ultrasonic treatment for 1h, heating in 35 deg.C water bath for extraction for 8h, filtering, centrifuging to obtain supernatant, repeating twice, mixing solutions, concentrating to 50.0mL, and freeze drying to obtain herba Artemisiae Annuae water extract.
Pulverizing aloe into fine powder, weighing 50g of aloe fine powder, adding an ethanol-water mixed solution, wherein the volume percentage of ethanol in the ethanol-water mixed solution is 50%, the material-liquid ratio is 1:10, placing the aloe fine powder and the ethanol-water mixed solution in a round-bottom flask, heating and refluxing in a water bath for 60min at the temperature of 60 ℃, repeating twice, combining supernatants, concentrating to 50mL, and freeze-drying to obtain the aloe extract.
Pulverizing Glycyrrhrizae radix into fine powder, sieving with 60 mesh sieve to obtain Glycyrrhrizae radix fine powder, sealing in plastic bag, and placing in dry place. Weighing 50g of licorice fine powder, adding 500g of water, extracting for 2 times at 95 ℃ for 2h each time, centrifuging to obtain supernatant, concentrating under reduced pressure, and drying to obtain licorice aqueous extract.
Pulverizing Coicis semen decoction pieces, sieving with 60 mesh sieve to obtain Coicis semen powder, sealing in plastic bag, placing in cool and dry place, weighing 50g Coicis semen powder, adding ethanol-water mixed solution, wherein ethanol content of 90% by volume in the ethanol-water mixed solution, performing hot reflux extraction at 65 deg.C for 120min at a material-liquid ratio of 1:8, concentrating the filtrate, and drying to obtain Coicis semen extract.
Pulverizing radix Angelicae Dahuricae in pulverizer, sieving with 0.42mm (40 mesh) sieve, sealing in plastic bag, and placing in cool and dry place. Weighing 50.0g of radix angelicae dahuricae powder, adding into a 1L round-bottom flask, adding 500.0mL of distilled water under stirring, heating in a water bath at 35 ℃ for extraction for 8h, filtering, centrifuging, collecting supernatant, concentrating to 50.0mL, and freeze-drying to obtain the radix angelicae dahuricae water extract.
Pulverizing Poria cocos (Schw.) wolf in a pulverizer, sieving with a 40-mesh sieve with a pore diameter of 0.42mm to obtain Poria cocos coarse powder, sealing in a plastic bag, placing in a cool and dry place for later use, weighing 50.0g Poria cocos coarse powder, adding 500.0mL of ethanol-water mixed solution, wherein ethanol is 70% by volume in the ethanol-water mixed solution, performing ultrasonic extraction at 25 ℃ for 20.0min, performing ultrasonic extraction at 200Hz, filtering, repeating the above operation on filter residues for 2 times, combining filtrates, concentrating to 500mL, centrifuging to obtain supernatant, concentrating under reduced pressure to 50.0mL, and freeze-drying to obtain Poria cocos extract.
Obtaining a traditional Chinese medicine group extract composition according to the mass ratio relation of the sweet wormwood herb water extract, the aloe extract, the liquorice water extract, the coix seed extract, the angelica dahurica water extract and the white poria cocos extract recorded in the group A in the table 1;
adding 28.185 parts of distilled water into a 250.0mL beaker under stirring, heating to 70 ℃ and keeping for 20min, sequentially adding 0.300 part of accurately weighed traditional Chinese medicine extract composition, 0.03 part of methyl paraben, 1.2 parts of glycerol, 0.06 part of odor regulator and 0.06 part of azone, stirring until the mixture is dissolved, and cooling to 40 ℃ after the sterilization is finished to obtain a water phase.
Regulating the pH value of the water phase to 7.2 by using triethanolamine, adding 0.015 part of sodium carboxymethylcellulose and 9400.15 parts of carbomer, fully dissolving, and standing until swelling is complete to obtain the traditional Chinese medicine extract gel wash-free mask.
Examples 2 to 16
The preparation methods of examples 2 to 16 are basically the same as those of example 1 except that: obtaining a traditional Chinese medicine group extract composition according to the mass ratio of the sweet wormwood herb water extract, the aloe extract, the liquorice water extract, the coix seed extract, the angelica dahurica water extract and the white poria extract recorded in the table 1; the components of the traditional Chinese medicine extract gel no-wash mask were obtained in parts by mass in table 2.
TABLE 1 Mass ratio of the components of the Chinese medicinal composition
Table 2 traditional Chinese medicine extract gel no-clean mask components in parts by weight
Test example
(1) Water retention and moisture retention Performance test
1.1 simulation of the absorption State of the skin in a vacuum Environment
Simulating real human skin with a medical breathable adhesive tape, directly and uniformly coating 0.5g of the traditional Chinese medicine extract gel no-clean facial mask prepared in examples 1-16 on the medical breathable adhesive tape at room temperature, and accurately weighing the mass, wherein the record is m1Then, the sample was placed in a vacuum desiccator for 1 hour, and then the permeable adhesive tape was taken out, and the moisture lost by the inner surface film sample was measured and calculated for 1 hour, where the lost moisture was m1-m2. The test results are shown in table 3. Table 3 shows the moisturizing performance of the products prepared in the examples of the present invention under absolute dry conditions.
Table 3 Water holding Properties of the leave-on mask of herbal extract gel prepared in examples 1 to 16 in vacuum
| Experiment number | m1 | m2 | Loss of water (m)1-m2) |
| 1 | 0.50 | 0.03 | 0.47 |
| 2 | 0.50 | 0.05 | 0.45 |
| 3 | 0.50 | 0.09 | 0.42 |
| 4 | 0.50 | 0.11 | 0.40 |
| 5 | 0.51 | 0.08 | 0.42 |
| 6 | 0.50 | 0.07 | 0.44 |
| 7 | 0.51 | 0.06 | 0.45 |
| 8 | 0.51 | 0.07 | 0.44 |
| 9 | 0.50 | 0.06 | 0.44 |
| 10 | 0.50 | 0.05 | 0.45 |
| 11 | 0.50 | 0.10 | 0.40 |
| 12 | 0.50 | 0.08 | 0.42 |
| 13 | 0.50 | 0.06 | 0.44 |
| 14 | 0.50 | 0.08 | 0.42 |
| 15 | 0.50 | 0.09 | 0.41 |
| 16 | 0.50 | 0.09 | 0.41 |
1.2 simulated absorption state of skin under 85% and 62% humidity environment
Simulating real human skin with a medical breathable adhesive tape, directly and uniformly coating 0.5g of the traditional Chinese medicine extract gel no-clean facial mask prepared in examples 1-16 on the medical breathable adhesive tape at room temperature, accurately weighing the mass, and recording the mass as H0Then placing the sample in a dryer with relative humidity close to 82% and 62% humidity for 4H, 8H and 24H, taking out the breathable adhesive tape, accurately weighing the mass of each sample respectively, and recording as HnCalculating the moisture retention rate according to the formula (1)
The results are shown in tables 4 and 5.
The moisture retention rate performance of the traditional Chinese medicine extract gel no-clean facial mask prepared in examples 1 to 16 in the environment with 482% humidity
TABLE 562% humidity the moisturizing rate performance of the leave-on facial mask of herbal extract gel prepared in examples 1-16
(2) Antioxidant property
112.0mg of DPPH (1, 1-diphenyl-2-trinitrophenylhydrazine) is accurately weighed, dissolved in absolute ethyl alcohol and the volume is adjusted to 100.0 mL. Taking 2.0mL of DPPH ethanol solution, and measuring the absorbance value A at 519nm0The value is obtained. The method is the same as that for measuring the traditional Chinese medicine extract gel no-clean facial mask (1.0mL) and DPPH (1, 1-diphenyl-2-trinitrobenzene) in examples 1-16Hydrazine radical) ethanol solution (3.0mL) after mixing absorbance AtValue, and absorbance A of the sample solution (1.0mL) after mixing with absolute ethanol (3.0mL)bThe DPPH-clearance (S) of the facial mask solution was calculated according to the formula (2), and the results are shown in Table 6.
TABLE 6 antioxidant Properties of the leave-in-mask pack of herbal extract gel prepared in examples 1-16
| Experiment number | A0 | At | Ab | Clearance S (%) |
| 1 | 1.03 | 0.12 | 0.10 | 98.43 |
| 2 | 1.03 | 0.18 | 0.17 | 98.36 |
| 3 | 1.03 | 0.17 | 0.27 | 100.00 |
| 4 | 1.03 | 0.22 | 0.21 | 99.07 |
| 5 | 1.03 | 0.20 | 0.13 | 93.19 |
| 6 | 1.03 | 0.27 | 0.12 | 84.93 |
| 7 | 1.03 | 0.29 | 0.14 | 85.19 |
| 8 | 1.03 | 0.30 | 0.25 | 94.82 |
| 9 | 1.03 | 0.59 | 0.15 | 57.17 |
| 10 | 1.03 | 0.38 | 0.11 | 73.12 |
| 11 | 1.03 | 0.23 | 0.26 | 100.00 |
| 12 | 1.03 | 0.23 | 0.52 | 100.00 |
| 13 | 1.03 | 0.63 | 0.08 | 46.21 |
| 14 | 1.03 | 0.29 | 0.15 | 86.05 |
| 15 | 1.03 | 0.41 | 0.37 | 95.89 |
| 16 | 1.03 | 0.35 | 0.32 | 97.02 |
Comparative example 1
The preparation method of comparative example 1 is substantially the same as that of example 1 except that: the mass ratio of the sweet wormwood water extract to the aloe extract to the liquorice water extract to the coix seed extract to the dahurian angelica root water extract to the white poria extract is 1:0.5:1:1:1: 1. The test results for comparative example 1 were: the moisture retention rate after 4 hours under 86% humidity was 65%, the oxidation resistance rate was 85%, and the pH of a solution obtained by dissolving 0.2g of the extract in 20mL of deionized water was 6.8.
Comparative example 2
The preparation method of comparative example 1 is substantially the same as that of example 1 except that: the mass ratio of the sweet wormwood water extract to the aloe extract to the liquorice water extract to the coix seed extract to the dahurian angelica root water extract to the white poria extract is 1:2:0.2:1:1: 1. The test results for comparative example 2 were: the moisture retention rate after 4 hours under 86% humidity condition was 80%, the oxidation resistance rate was 89%, and the pH of a solution obtained by dissolving 0.2g of the extract with 20mL of deionized water was 7.2.
Comparative example 3
The production method of comparative example 1 is substantially the same as that of example 1 except that: the mass ratio of the sweet wormwood water extract to the aloe extract to the liquorice water extract to the coix seed extract to the dahurian angelica root water extract to the white poria extract is 1:1:1:1: 3. The test results for comparative example 3 were: the moisture retention rate after 4 hours at 86% humidity was 82%, the oxidation resistance rate was 78%, and the pH of a solution obtained by dissolving 0.2g of the extract in 20mL of deionized water was 7.3.
Comparative example 4
The preparation method of comparative example 1 is substantially the same as that of example 1 except that: the mass ratio of the sweet wormwood water extract to the aloe extract to the liquorice water extract to the coix seed extract to the dahurian angelica root water extract to the white poria extract is 1:1:1:0.1:2: 2. The test results for comparative example 4 were: the moisture retention rate after 4 hours at 86% humidity was 74%, the oxidation resistance rate was 82%, and the pH of a solution obtained by dissolving 0.2g of the extract in 20mL of deionized water was 7.4.
Comparative example 5
The preparation method of comparative example 1 was substantially the same as that of example 1 except that carbomer 940 was replaced with a mixture of sodium alginate and calcium carbonate mixed in a mass ratio of 1:1, and a stable gel could not be formed.
The data in tables 3 to 6 in the above test examples can be used to obtain: the invention provides a traditional Chinese medicine extract gel no-clean facial mask which comprises a composite traditional Chinese medicine extract active component, wherein the traditional Chinese medicine extract active component is a traditional Chinese medicine extract composition comprising a sweet wormwood herb water extract, an aloe extract, a liquorice water extract, a coix seed extract, a radix angelicae water extract and a white poria extract.
Although the present invention has been described in detail with reference to the above embodiments, it is only a part of the embodiments of the present invention, not all of the embodiments, and other embodiments can be obtained without inventive step according to the embodiments, and the embodiments are within the scope of the present invention.
Claims (10)
1. The traditional Chinese medicine extract composition is characterized by comprising the following components in parts by mass:
0.5-2.5 parts of sweet wormwood herb water extract, 0.6-2.6 parts of aloe extract, 0.8-3.1 parts of liquorice water extract, 0.4-2.8 parts of coix seed extract, 0.1-4 parts of radix angelicae water extract and 1-2 parts of poria alba extract.
2. The traditional Chinese medicine extract composition as claimed in claim 1, wherein the preparation method of the sweet wormwood water extract comprises the following steps:
ultrasonically mixing sweet wormwood powder and water to obtain sweet wormwood mixed solution;
heating and extracting the sweet wormwood mixed solution to obtain the sweet wormwood aqueous extract;
the mass ratio of the sweet wormwood powder to the volume of water is 1g:10 mL; the temperature of the heating extraction is 35 ℃, the heat preservation time of the heating extraction is 8h, and the times of the heating extraction are 2 times.
3. The composition of claim 1, wherein the aloe vera extract is prepared by a method comprising the steps of:
mixing aloe powder with ethanol-water mixed solvent to obtain aloe mixed solution;
heating and extracting the aloe mixed solution to obtain the aloe extract;
the material-liquid ratio of the aloe mixed liquid is 1: 10; the temperature of the heating extraction is 60 ℃, the heat preservation time of the heating extraction is 60min, the times of the heating extraction are 2 times, and the volume content of ethanol in the ethanol-water mixed solvent is 50%.
4. The composition of claim 1, wherein the preparation method of the licorice aqueous extract comprises the following steps:
mixing the liquorice powder with a mixed solvent of water to obtain a liquorice mixed solution;
heating and extracting the licorice mixed solution to obtain the licorice aqueous extract;
the material-liquid ratio of the liquorice mixed liquor is 1: 10; the temperature of the heating extraction is 95 ℃, the heat preservation time of the heating extraction is 2min, and the times of the heating extraction are 2 times.
5. The composition of claim 1, wherein the preparation method of the coix seed extract comprises the following steps:
mixing the coix seed powder with a mixed solvent of ethanol and water to obtain coix seed mixed solution;
heating and extracting the coix seed mixed solution to obtain the coix seed extract;
the material-liquid ratio of the coix seed mixed liquid is 1: 8; the temperature of the heating extraction is 65 ℃, the heat preservation time of the heating extraction is 120min, and the volume content of the ethanol in the ethanol-water mixed solvent is 90%.
6. The traditional Chinese medicine extract composition as claimed in claim 1, wherein the preparation method of the radix angelicae aqueous extract comprises the following steps:
ultrasonically mixing the angelica dahurica powder with water to obtain an angelica dahurica mixed solution;
heating and extracting the radix angelicae mixed solution to obtain the radix angelicae water extract;
the ratio of the mass of the angelica dahurica powder to the volume of the water is 1g:10 mL; the temperature of the heating extraction is 35 ℃, and the heat preservation time of the heating extraction is 8 h.
7. The herbal extract composition of claim 1, wherein the preparation method of the poria cocos wolf extract comprises the following steps:
mixing the white poria powder with a mixed solvent of ethanol and water to obtain a white poria mixed solution;
ultrasonically extracting the white poria mixed solution to obtain the white poria extract;
the mass ratio of the white poria cocos powder to the volume of water is 1g:10 mL; the temperature of the ultrasonic extraction is 25 ℃, the heat preservation time of the ultrasonic extraction is 200min, and the ultrasonic frequency of the ultrasonic extraction is 200 Hz; the volume content of ethanol in the ethanol-water mixed solvent is 70%.
8. Use of the herbal extract composition of any one of claims 1 to 7 in cosmetics.
9. The traditional Chinese medicine extract gel wash-free mask is characterized by comprising the following components in parts by mass:
3-15 parts of an active component of a composite traditional Chinese medicine extract, 0.6-1.5 parts of a penetrating agent, 1.5-3 parts of a gel matrix, 12-30 parts of glycerol, 0.6 part of an odor regulator, 0.15 part of an emulsifier, 0.3 part of a preservative and 230-285 parts of water; the active component of the compound traditional Chinese medicine extract is the traditional Chinese medicine extract composition of any one of claims 1-7.
10. The preparation method of the traditional Chinese medicine extract gel no-clean mask as claimed in claim 9, which is characterized by comprising the following steps:
mixing the active components of the compound Chinese medicinal extract, penetrant, glycerin, odor regulator, preservative and water to obtain water phase;
and mixing the water phase, the emulsifier and the gel matrix to obtain the traditional Chinese medicine extract gel no-clean facial mask.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115444086A (en) * | 2022-09-23 | 2022-12-09 | 浙江中医药大学 | Health-care beverage with whitening and skin-brightening functions and preparation method and application thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115444086A (en) * | 2022-09-23 | 2022-12-09 | 浙江中医药大学 | Health-care beverage with whitening and skin-brightening functions and preparation method and application thereof |
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