CN114569284A

CN114569284A - Brain protection device

Info

Publication number: CN114569284A
Application number: CN202210319779.8A
Authority: CN
Inventors: 赵向前; 沈斌; 汪泽辉
Original assignee: Shanghai Yixin Medical Devices Co ltd
Current assignee: Shanghai Yixin Medical Devices Co ltd
Priority date: 2022-03-29
Filing date: 2022-03-29
Publication date: 2022-06-03
Anticipated expiration: 2042-03-29
Also published as: CN114569284B

Abstract

The application provides a brain protection device, including first filter sleeve, partial guide spare and second filter sleeve. The first end of the first filter sleeve is provided with a first opening; the first filter sleeve is embedded in the head-arm trunk, and the first opening is communicated with the aortic arch; the deflector is connected with the first end of the first filter sleeve; the deflector is used for being arranged in an aortic arch and is used for covering a left common carotid artery and a left subclavian artery; a first end of the second filter sleeve is provided with a second opening, and the first end of the second filter sleeve is connected with one end of the deflector, which is far away from the first filter sleeve; the second filtering sleeve is embedded in the descending aorta, and the second opening is communicated with the aortic arch. Foretell brain protection device can prevent debris such as thrombus from entering into in the brachiocephalic trunk, left common carotid artery, left subclavian artery and descending aorta, can make brachiocephalic trunk, left common carotid artery and left subclavian artery all protected, further reduces the risk of postoperative new development of cerebral apoplexy.

Description

Brain protection device

Technical Field

The application relates to the technical field of brain protection devices, in particular to a brain protection device.

Background

Currently, during transcatheter aortic valve replacement, stenotic material surrounding the valve may slough off during implantation of the prosthetic valve. Again, atheroma along and in the aorta and aortic arch may shed as the TAVR catheter is advanced toward the diseased aortic valve and subsequently withdrawn after implantation is complete. In addition, debris from the catheter itself may also be stripped away during delivery and implantation. These various forms of vascular debris, whether native or foreign, may travel into one or more cerebral arteries causing a stroke. The existing brain protection devices are used for filtering the blood vessel debris, but the existing brain protection devices cannot completely cover the arch of the aorta and can not completely protect the brachiocephalic trunk (innominate artery), the left common carotid artery and the left subclavian artery (branch containing vertebral artery) which accounts for about 10 percent of cerebral perfusion.

Disclosure of Invention

An object of the embodiment of the application is to provide a brain protection device, which is used for solving the problem that the existing brain protection device can not protect all of the brachiocephalic trunk, the left common carotid artery and the left subclavian artery.

An embodiment of the present application provides a brain protection device, including:

the first end of the first filter sleeve is provided with a first opening; the first filter sleeve is embedded in the head-arm trunk, and the first opening is communicated with the aortic arch;

a deflector connected to a first end of the first filter sleeve; the deflector is for placement in the aortic arch, the deflector for covering the left common carotid artery and the left subclavian artery;

a second opening is formed in the first end of the second filter sleeve, and the first end of the second filter sleeve is connected with one end, far away from the first filter sleeve, of the deflector; the second filtering sleeve is embedded in the descending aorta, and the second opening is communicated with the aortic arch.

The brain protection device comprises a first filter sleeve, a deflector and a second filter sleeve. The brachiocephalic trunk, the left common carotid artery, the left subclavian artery and the descending aorta of the human body are respectively communicated with the aortic arch; the first filtering sleeve is embedded in the head-arm trunk, the deflector covers the left common carotid artery and the left subclavian artery, the second filtering sleeve is embedded in the descending aorta, and the deflector is connected with the first filtering sleeve and the second filtering sleeve to form an integral protection ring; the first filtering sleeve, the deflector and the second filtering sleeve are respectively used for blocking and filtering sundries such as thrombus and the like, so that normal circulation of blood is ensured, and meanwhile, the sundries such as thrombus and the like are prevented from entering the brachiocephalic trunk, the left common carotid artery, the left subclavian artery and the descending aorta; the deflector can guide impurities such as thrombus and the like to flow to the first filter sleeve or the second filter sleeve; the first filter sleeve and the second filter sleeve can contain and hold sundries such as thrombus and prevent the sundries such as thrombus from flowing continuously after being blocked; therefore, the brain protection device can protect the brachiocephalic trunk, the left common carotid artery and the left subclavian artery, and further reduce the risk of new stroke after operation.

In one embodiment, the brain protection device comprises a connecting frame, the second filter sleeve is connected with the deflector through the connecting frame, one end of the connecting frame is connected with one end of the deflector, which is far away from the first filter sleeve, and the other end of the connecting frame is connected with the first end of the second filter sleeve.

In one embodiment, the connection frame is a closed structure.

In one embodiment, the deflector comprises two deflector rods which are connected end to form an annular frame, and a deflector film matched with an opening of the annular frame is arranged in the annular frame; the deflector film is used for covering the left common carotid artery and the left subclavian artery.

In one embodiment, a first end of a first one of the deflection rods is connected with a first end of a second one of the deflection rods to form a first end point, a second end of the first one of the deflection rods is connected with a second end of the second one of the deflection rods to form a second end point, the first end point forms a connection point connected with the first filter sleeve, and the second end point forms a connection point connected with the second filter sleeve.

In one embodiment, the two deflection arms are curved in an arc away from each other.

In one embodiment, the first filter sleeve comprises a first support frame and a first filter membrane; the first support frame comprises a plurality of first support rods, every two first support rods are connected end to form a mesh, the first support frame is of a net structure, and the first support frame is provided with the first opening; the first filter membrane is arranged in the first support frame, and the outer wall surface of the first support frame is used for being abutted against the inner wall of the head arm.

In one embodiment, the first filter membrane is provided with first filter holes, and the pore size of the first filter holes is 50-500 um.

In one embodiment, the second filter sleeve comprises a second support frame and a second filter membrane; the second support frame comprises a plurality of second support rods, every two second support rods are connected end to form a mesh, the second support frame is of a net structure, and the second support frame is provided with a second opening; the second filtering membrane is arranged in the second supporting frame, and the outer wall surface of the second supporting frame is used for being abutted to the inner wall of the descending aorta.

In one embodiment, the second filter membrane is provided with second filter holes, and the pore size of the second filter holes is 50-500 um.

In one embodiment, the first filter sleeve has a second end opposite to the first end of the first filter sleeve, and the second end of the first filter sleeve is provided with a first recovery member for detachable connection with an external recovery device punctured into the head arm stem.

In one embodiment, the first recovery member comprises a first recovery hook coupled to the second end of the first filter sleeve, the first recovery hook configured to hook over an external loop that penetrates into the head-arm stem.

In one embodiment, the first recovery member comprises a hollow post coupled to the second end of the first filter cartridge, and a threaded connector is disposed within the hollow post for threaded connection with an external delivery device inserted into the head stem.

In one embodiment, the first recovery hook is formed by rotating and cutting a part of the hollow column from the end of the hollow column connected with the first filter sleeve to the end of the hollow column far away from the first filter sleeve.

In one embodiment, the second filter sleeve has a second end opposite the first end of the second filter sleeve, the second end of the second filter sleeve being provided with a second retrieval member for detachable connection with an external retrieval device for puncturing into the descending aorta.

In one embodiment, the second retrieval member includes a second retrieval hook coupled to the second end of the second filter sleeve for hooking over an external loop that is punctured into the descending aorta.

In one embodiment, the second recovery hook comprises a connecting part, a bending part and a hooking part which are sequentially connected, the connecting part is connected with the second end of the second filter sleeve, and one end of the connecting part, which is far away from the second filter sleeve, is connected with the bending part; the connecting part extends along the length direction of the descending aorta, and the bending part and the connecting part form an included angle.

In one embodiment, the first filtering sleeve, the deflector and the second filtering sleeve are respectively of a telescopic structure, and the first filtering sleeve, the deflector and the second filtering sleeve are respectively retractable in a delivery sheath for puncturing into an aortic arch.

In one embodiment, the material of the first filter sleeve, the material of the deflector and the material of the second filter sleeve each comprise a shape memory material.

In one embodiment, the first filter sleeve, the deflector and the second filter sleeve are integrally formed.

In one embodiment, the first filter sleeve comprises a first woven sleeve and a first filter membrane; the first knitted jacket is a mesh structure, and the first knitted jacket has the first opening; the first filter membrane is arranged in the first woven sleeve, and the outer wall surface of the first woven sleeve is used for being abutted against the inner wall of the head arm stem.

In one embodiment, the second filter sleeve comprises a second woven sleeve and a second filter membrane; the second woven sleeve is of a net structure and is provided with the second opening; the second filtering membrane is arranged in the second weaving sleeve, and the outer wall surface of the second weaving sleeve is used for being abutted against the inner wall of the descending aorta.

Additional features and advantages of the disclosure will be set forth in the description which follows, or in part may be learned by the practice of the above-described techniques of the disclosure.

In order to make the aforementioned objects, features and advantages of the present application more comprehensible, preferred embodiments accompanied with figures are described in detail below.

Drawings

To more clearly illustrate the technical solutions of the embodiments of the present application, the drawings that are required to be used in the embodiments of the present application will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present application and therefore should not be considered as limiting the scope, and that those skilled in the art can also obtain other related drawings based on the drawings without inventive efforts.

Fig. 1 is a schematic structural diagram of a brain protection device according to an embodiment of the present application;

fig. 2 is a schematic structural diagram of a brain protection device according to an embodiment of the present application and an application thereof;

FIG. 3 is a schematic structural diagram of a first filter sleeve provided in an embodiment of the present application;

FIG. 4 is a schematic view of a second filter sleeve provided in the embodiment of the present application for intercepting foreign objects such as thrombus;

fig. 5 is a schematic partial structural diagram of a brain protection device according to an embodiment of the present application;

fig. 6 is a schematic structural diagram of a brain protection device according to another embodiment of the present application and an application thereof;

fig. 7 is a schematic structural diagram of a brain protection device according to another embodiment of the present application and an application thereof.

Reference numerals:

a brain protection device 10; a head-arm shaft 20; an aortic arch 30; the left common carotid artery 40; the left subclavian artery 50; the descending aorta 60; a thrombus 70; a first filter housing 100; a first opening 101; a first support frame 110; the first support rod 111; a first recovery element 130; a first recovery hook 131; a hollow column 132; a first knitted jacket 140; a deflector 200; a deflector rod 210; a ring frame 220; a second filter sleeve 300; a second opening 301; a second support frame 310; a second filter membrane 320; a second recovery element 330; the second recovery hook 331; a connecting portion 331 a; a bent portion 331 b; a hooking portion 331 c; a second braided sleeve 340; the frame 400 is connected.

Detailed Description

The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and not all of the embodiments. The components of the embodiments of the present application, generally described and illustrated in the figures herein, can be arranged and designed in a wide variety of different configurations. Thus, the following detailed description of the embodiments of the present application, presented in the accompanying drawings, is not intended to limit the scope of the claimed application, but is merely representative of selected embodiments of the application. All other embodiments, which can be derived by a person skilled in the art from the embodiments of the present application without making any creative effort, shall fall within the protection scope of the present application.

In the present application, the terms "upper", "lower", "left", "right", "front", "rear", "top", "bottom", "inner", "outer", "middle", "vertical", "horizontal", "lateral", "longitudinal", and the like indicate an orientation or positional relationship based on the orientation or positional relationship shown in the drawings. These terms are used primarily to better describe the present application and its embodiments, and are not used to limit the indicated devices, elements or components to a particular orientation or to be constructed and operated in a particular orientation.

Moreover, some of the above terms may be used to indicate other meanings besides the orientation or positional relationship, for example, the term "on" may also be used to indicate some kind of attachment or connection relationship in some cases. The specific meaning of these terms in this application will be understood by those of ordinary skill in the art as appropriate.

Furthermore, the terms "mounted," "disposed," "provided," "connected," and "connected" are to be construed broadly. For example, it may be a fixed connection, a removable connection, or a unitary construction; can be a mechanical connection, or a point connection; either directly or indirectly through intervening media, or may be an internal communication between two devices, elements or components. The specific meaning of the above terms in the present application can be understood by those of ordinary skill in the art as appropriate.

Furthermore, the terms "first," "second," and the like, are used primarily to distinguish one device, element, or component from another (the specific nature and configuration may be the same or different), and are not used to indicate or imply the relative importance or number of the indicated devices, elements, or components. "plurality" means two or more unless otherwise specified.

In one embodiment, a brain protection device includes a first filter sleeve, a deflector, and a second filter sleeve. A first opening is formed in the first end of the first filter sleeve; the first filter sleeve is embedded in the head-arm trunk, and the first opening is communicated with the aortic arch; the deflector is connected with the first end of the first filter sleeve; the deflector is for placement in the aortic arch, the deflector for covering the left common carotid artery and the left subclavian artery; a second opening is formed in the first end of the second filter sleeve, and the first end of the second filter sleeve is connected with one end, far away from the first filter sleeve, of the deflector; the second filtering sleeve is embedded in the descending aorta, and the second opening is communicated with the aortic arch.

As shown in fig. 1 and 2, an embodiment of a brain protection device 10 includes a first filter sleeve 100, a deflector 200, and a second filter sleeve 300. Referring to fig. 3, a first opening 101 is formed at a first end of the first filter sleeve 100. The first filtering sleeve 100 is embedded in the head-arm stem 20, and the first opening 101 is used for communicating with the aortic arch 30. The deflector 200 is coupled to a first end of the first filter sleeve 100. The deflector 200 is adapted to be positioned in the aortic arch 30, the deflector 200 is adapted to cover the left common carotid artery 40 and the left subclavian artery 50, i.e. the deflector 200 is adapted to cover the ostia of the left common carotid artery 40 and the left subclavian artery 50, respectively, communicating with the aortic arch 30. A second opening 301 is opened at a first end of the second filter sleeve 300, and the first end of the second filter sleeve 300 is connected to an end of the deflector 200 away from the first filter sleeve 100. The second filtering sleeve 300 is configured to be embedded in the descending aorta 60, and the second opening 301 is configured to communicate with the aortic arch 30.

The brain protection device 10 comprises a first filter sleeve 100, a deflector 200 and a second filter sleeve 300. The brachiocephalic trunk 20, the left common carotid artery 40, the left subclavian artery 50 and the descending aorta 60 of the human body are respectively communicated with the aortic arch 30; the first filtering sleeve 100 is embedded in the head-arm trunk 20, the deflector 200 covers the left common carotid artery 40 and the left subclavian artery 50, the second filtering sleeve 300 is embedded in the descending aorta 60, and the deflector 200 connects the first filtering sleeve 100 and the second filtering sleeve 300 to form an integral protective ring; referring to fig. 4, the first filtering sleeve 100, the deflector 200 and the second filtering sleeve 300 are respectively used for blocking and filtering impurities such as thrombus 70, so as to prevent the impurities such as thrombus 70 from entering the brachiocephalic trunk 20, the left common carotid artery 40, the left subclavian artery 50 and the descending aorta 60 while ensuring normal blood circulation; the deflector 200 can guide impurities such as thrombus 70 and the like, so that the impurities such as thrombus 70 and the like can flow to the first filter sleeve 100 or the second filter sleeve 300; the first filter sleeve 100 and the second filter sleeve 300 can accommodate and hold sundries such as thrombus 70 and prevent the sundries such as thrombus 70 from flowing continuously after being blocked; therefore, the brain protection device 10 can completely cover the aortic arch 30, so that the brachiocephalic trunk 20, the left common carotid artery 40 and the left subclavian artery 50 are all protected, and the risk of new stroke after operation is further reduced.

In order to provide stability to the brain protection device 10, in one embodiment, as shown in figure 2, the brain protection device 10 further comprises a connecting frame 400, the second filter sleeve 300 is connected with the deflector 200 through the connecting frame 400, and one end of the connection frame 400 is connected to one end of the deflector 200 away from the first filter sleeve 100, the other end of the connection frame 400 is connected to the first end of the second filter sleeve 300, the connection frame 400 functions to connect the deflector 200 and the second filter sleeve 300, and furthermore, compared to a single rod member, the connection frame 400 has a planar structure, which, when disposed in an artery, the planar configuration of the attachment frame 400 may limit the deflection of the deflector 200 and the second filter sleeve 300 when the deflector 200 and the second filter sleeve 300 are subjected to blood flow impingement, so that the deflector 200 and the second filter sleeve 300 are stably arranged, and the whole brain protection device 10 is stably arranged. In this embodiment, the connection frame 400 is configured to be disposed at a position where the aortic arch 30 and the descending aorta 60 communicate with each other. In one embodiment, the number of the connection frames 400 is plural, the connection frames 400 are connected in sequence, a first connection frame 400 is connected to the deflector 200, and a last connection frame 400 is connected to the second filter sleeve 300. In one embodiment, the shape of the connection frame 400 is a polygon. In one embodiment, the connection frame 400 is a quadrilateral shape. In one embodiment, the connecting frame 400 is diamond-shaped.

In order to keep the connection frame 400 stable, in one embodiment, the connection frame 400 is in a closed configuration, such that the connection frame 400 is in a closed configuration, and compared to the connection frame 400 that is disconnected, the closed connection frame 400 has no moving point when being impacted by blood flow, so as to keep stable, and when the connection frame 400 can be extended and retracted, the connection frame 400 is convenient to be extended and retracted, so as to avoid being unable to be retracted due to disconnection.

In other embodiments, the brain protection device 10 further comprises a connecting assembly, the connecting assembly comprises a plurality of connecting wires, one end of each connecting wire is connected with one end of the deflector 200 far away from the first filtering sleeve 100, the other end of each connecting wire is connected with the first end of the second filtering sleeve 300, the plurality of connecting wires are arranged along a direction perpendicular to the length direction of the connecting wires, the deflector 200 and the second filtering sleeve 300 are connected through the plurality of connecting wires, and the deflector 200 and the second filtering sleeve 300 are stabilized to prevent deflection caused by the impact of blood flow.

In one embodiment, as shown in fig. 5, the deflector 200 comprises two deflector rods 210, the two deflector rods 210 are connected end to form an annular frame 220, that is, one end of a first deflector rod 210 is connected to one end of a second deflector rod 210, the other end of the first deflector rod 210 is connected to the other end of the second deflector rod 210, and a deflector film adapted to the opening of the annular frame 220 is disposed in the annular frame 220; the deflector is used for covering the left common carotid artery 40 and the left subclavian artery 50, in the embodiment, the deflector covers the annular frame 220, impurities such as thrombus 70 are filtered and guided through the deflector, and the annular frame 220 formed by connecting the two deflector 210 is used for fixing the deflector. In one embodiment, the ring frame 220 is a closed structure, and compared to the opened ring frame 220, the closed ring frame 220 has no moving point when being impacted by blood flow, so that the closed ring frame 220 can be kept stable, and when the ring frame 220 can be stretched, the ring frame 220 can be conveniently stretched, so that the ring frame is prevented from being incapable of being contracted due to being opened, and a deflection membrane can be conveniently and stably arranged. In one embodiment, the membrane has filter holes for filtering debris such as thrombus 70. Illustratively, the polarization film is a polymer film. In one embodiment, the pore size of the filter pores is 50-500 um, so that impurities such as thrombus 70 can be effectively filtered, and the normal circulation of blood can be ensured. In one embodiment, the pore size of the filter pores is 80-300 um. In one embodiment, the pore size of the filter pores is 100 um.

In one embodiment, the first end of a first one of the deflection rods 210 is connected to the first end of a second one of the deflection rods 210 to form a first end point, the second end of the first one of the deflection rods 210 is connected to the second end of the second one of the deflection rods 210 to form a second end point, the first end point forms a connection point with the first filtering sleeve 100, the second end point forms a connection point with the second filtering sleeve 300, and the first end point and the second end point are two end points in the length direction of the annular frame 220, respectively, so as to ensure that the annular frame 220 and the deflection membrane can cover the complete left common carotid artery 40 and the left subclavian artery 50.

In order to more fully cover the left common carotid artery 40 and the left subclavian artery 50, in one embodiment, the two biasing rods 210 are curved away from each other in an arc shape, so that the width of the annular frame 220 can be ensured while the length of the annular frame 220 is ensured, thereby the biasing member 200 has a larger covering area and more complete coverage protection is ensured for the left common carotid artery 40 and the left subclavian artery 50. In one embodiment, the annular frame 220 is an oval frame, allowing the deflector 200 to have a greater footprint.

In other embodiments, the annular frame 220 may be a frame with other shapes.

In one embodiment, as shown in fig. 3, the first filter sleeve 100 comprises a first support frame 110 and a first filter membrane (not shown); the first support frame 110 comprises a plurality of first support rods 111, every two first support rods 111 are connected end to form a mesh, the first support frame 110 is of a mesh structure, and the first support frame 110 is provided with the first opening 101; the first filtering membrane is disposed inside the first supporting frame 110 (please refer to the description of the number of modifications for disambiguation, and please refer to the description of the filtering membrane blocking the opening, which is similarly modified), the outer wall surface of the first supporting frame 110 is used for abutting against the inner wall of the head arm stem 20, so that the first supporting frame 110 formed by the plurality of first supporting rods 111 can be supported in the head arm stem 20, and the first filtering sleeve 100 can be firmly fixed by radial supporting force; the first filtering membrane is used for blocking and filtering sundries such as thrombus 70 and the like, and meanwhile, the sundries such as thrombus 70 and the like are held. In one embodiment, the mesh openings are polygonal in shape. In one embodiment, the plurality of meshes includes at least one of a triangle, a quadrangle, and a hexagon. In one embodiment, a majority of the mesh openings are quadrilateral in shape. In one embodiment, a majority of the mesh openings are diamond shaped. In one embodiment, the first filtration membrane is a polymeric membrane. In one embodiment, the first filtering membrane is provided with first filtering holes, and the pore size of the first filtering holes is 50-500 um, so that impurities such as thrombus 70 can be effectively filtered, and normal circulation of blood is ensured.

In one embodiment, as shown in FIG. 2, the second filter sleeve 300 comprises a second support frame 310 and a second filter membrane 320; the second supporting frame 310 comprises a plurality of second supporting rods 311, every two second supporting rods 311 are connected end to form a mesh, the second supporting frame 310 is of a net structure, and the second supporting frame 310 is provided with the second opening 301; the second filtering membrane 320 is disposed inside the second supporting frame 310 (note the modification here), and the outer wall surface of the second supporting frame 310 is used for abutting against the inner wall of the descending aorta 60, so that the second supporting frame 310 formed by the plurality of second supporting rods 311 can be supported in the descending aorta 60, and the second filtering sleeve 300 can be firmly fixed by radial supporting force; the second filtering membrane 320 is used for blocking and filtering foreign matters such as thrombus 70 and trapping foreign matters such as thrombus 70. In one embodiment, the mesh openings are polygonal in shape. In one embodiment, the plurality of meshes comprises at least one of a triangle, a quadrilateral and a hexagon. In one embodiment, a majority of the mesh openings are quadrilateral in shape. In one embodiment, a majority of the mesh openings are diamond shaped. In one embodiment, the first filtration membrane is a polymeric membrane. In one embodiment, the second filtering membrane 320 has second filtering holes, and the pore size of the second filtering holes is 50um to 500um, so that impurities such as thrombus 70 can be effectively filtered, and normal circulation of blood is ensured.

In order to ensure that the brain protection device 10 is easily recycled after being stored in the human body for a certain period of time, in one embodiment, as shown in fig. 3, the first filter sleeve 100 has a second end opposite to the first end of the first filter sleeve 100, the second end of the first filter sleeve 100 is provided with a first recovery piece 130, the first recovery piece 130 is used for being detachably connected with an external recovery device punctured into the head and arm trunk 20, the first recovery piece 130 is arranged, the external recovery device punctured into is connected with the first recovery piece 130, the whole brain protection device 10 is extracted from the head and arm trunk 20 and then extracted from the body through the radial artery or the brachial artery; therefore, the brain protection device 10 can be stored in a human body for a period of time, and the thrombus 70 and other impurities can be fully filtered and removed; for example, the brain protection device 10 can be stored in a human body for a week in combination with clinical needs, so as to ensure that impurities such as thrombus 70 are sufficiently filtered and removed, and further reduce the risk of new stroke after operation. For example, an external retrieval device may be inserted through the radial or brachial artery into the brachiocephalic trunk 20 and connected to the first retrieval member 130.

In order to facilitate the external recycling device to cooperate with the first recycling member 130, as shown in fig. 3, in one embodiment, the first recycling member 130 includes a first recycling hook 131, the first recycling hook 131 is connected to the second end of the first filter sleeve 100, and the first recycling hook 131 is used for hooking an external loop penetrated into the head-arm stem 20, so that the first recycling hook 131 is sleeved by the external loop to be quickly connected with the brain protection device 10, and thus the recycling efficiency of the brain protection device 10 is high.

In one embodiment, as shown in fig. 3, the first recovery member 130 includes a hollow column 132, the hollow column 132 is connected to the second end of the first filter sleeve 100, a screw is disposed in the hollow column 132, the screw is used for screwing with an external delivery device inserted into the head and arm stem 20, the screw can be used for screwing with the screw through the external delivery device when the brain protection device 10 is installed, pushing the screw, i.e. pushing the brain protection device 10 into a target position in a human body, and after the brain protection device 10 reaches the target position, the external delivery device is disengaged from the screw with the screw, and then drawing out the external delivery device; in addition, the brain protection device 10 can also be recovered by screwing the external delivery device with the screw member again. In one embodiment, the hollow column 132 has a mounting opening at an end thereof remote from the first filter cartridge 100, and a nut is welded inside the mounting opening, and the screw is the nut.

In one embodiment, from the end of the hollow column 132 connected to the first filter sleeve 100 to the end of the hollow column 132 far away from the first filter sleeve 100, a part of the hollow column 132 is cut by rotation to form the first recovery hook 131, so that the formed first recovery hook 131 has a large inner space, and cannot cut the same part of the hollow column 132 too deeply to avoid the breakage of the hollow column 132; and the collar is convenient to cover the first recovery hook 131 due to the large internal space and the long distribution length of the first recovery hook 131.

In one embodiment, as shown in fig. 2, the second filter sleeve 300 has a second end opposite to the first end of the second filter sleeve 300, the second end of the second filter sleeve 300 is provided with a second recovery member 330, the second recovery member 330 is detachably connected with an external recovery device punctured into the descending aorta 60, the second recovery member 330 is arranged, and the whole brain protection device 10 is extracted from the descending aorta 60 through the connection of the punctured external recovery device with the second recovery member 330 and then extracted from the outside through the femoral artery. For example, an external retrieval device may be punctured through the femoral artery into the descending aorta 60 and connected to the second retrieval member 330.

In one embodiment, as shown in fig. 2, the second recovery member 330 includes a second recovery hook 331, the second recovery hook 331 is connected to the second end of the second filtering sheath 300, and the second recovery hook 331 is used for hooking an external loop penetrated into the descending aorta 60, so that the second recovery hook 331 is sleeved by the external loop, and the brain protection device 10 can be quickly connected, thereby improving the recovery efficiency of the brain protection device 10.

In one embodiment, as shown in fig. 2, the second recovery hook 331 includes a connection portion 331a, a bending portion 331b and a hooking portion 331c connected in sequence, the connection portion 331a is connected to the second end of the second filter sleeve 300, and an end of the connection portion 331a away from the second filter sleeve 300 is connected to the bending portion 331 b; the connecting portion 331a extends along the length direction of the descending aorta 60, the bending portion 331b forms an included angle with the connecting portion 331a, so that the bending portion 331b forms a certain included angle with the connecting portion 331a, and the bending portion 331b can extend to a suspended position in the middle of the descending aorta 60 and be far away from the inner wall of the descending aorta 60, thereby avoiding damage to the inner wall of the descending aorta 60 during recovery. In one embodiment, the included angle is 30-150 degrees. In one embodiment, an end of the hooking portion 331c away from the bending portion 331b is bent toward the connecting portion 331a, i.e., toward the inner wall of the descending aorta 60, so as to improve the success rate of the external looping device in sleeving the hooking portion 331 c.

In one embodiment, as shown in fig. 6, the hooking portion 331c is a U-shaped structure, and the side wall of the U-shaped structure is parallel to the connecting portion 331a, so that the external loop can cover the hooking portion 331c, and the brain protection device 10 can be more stably driven to be drawn out, and driven along the direction parallel to the connecting portion 331a, i.e. the direction parallel to the inner wall of the descending aorta 60, so as not to damage the inner wall of the descending aorta 60.

In one embodiment, the first filtering sleeve 100, the deflector 200 and the second filtering sleeve 300 are respectively of a retractable structure, and the first filtering sleeve 100, the deflector 200 and the second filtering sleeve 300 are respectively retractable in a delivery sheath for puncturing into the aortic arch 30, so that the first filtering sleeve 100, the deflector 200 and the second filtering sleeve 300 can be retracted and can be accommodated in the delivery sheath during recovery, thereby ensuring successful recovery of the extracorporeal body; when the brain protection device 10 needs to be used, the first filter sleeve 100, the deflector 200 and the second filter sleeve 300 are sequentially released from the delivery sheath, or the second filter sleeve 300, the deflector 200 and the first filter sleeve 100 are sequentially released, so that all parts of the brain protection device 10 are positioned at a target position to intercept and filter impurities such as thrombus 70. In one embodiment, the connecting member is a telescopic structure, and the connecting member is retractable in the delivery sheath.

In one embodiment, the material of the first filter sleeve 100, the material of the deflector 200 and the material of the second filter sleeve 300 respectively comprise shape memory materials, wherein the material of the first support frame 110, the material of the deflector 210 and the material of the second support frame 310 respectively comprise shape memory materials, so that the first filter sleeve 100, the deflector 200 and the second filter sleeve 300 can be conveniently stretched and retracted, and can automatically return to an open state after being separated from the constraint of a self-contraction state. In one embodiment, the material of the first support frame 110, the material of the guide rod 210, and the material of the second support frame 310 are shape memory materials, for example, shape memory alloy or shape memory polymer materials. In one embodiment, the connecting frame 400 is made of a shape memory material.

In one embodiment, the material of the first filter sleeve 100, the material of the deflector 200, and the material of the second filter sleeve 300 respectively comprise one of an alloy, medical stainless steel, and a polymer material, and the material of the first support frame 110, the material of the deflector 210, and the material of the second support frame 310 respectively comprise one of an alloy, medical stainless steel, and a polymer material.

In one embodiment, the first filter sleeve 100, the deflector 200 and the second filter sleeve 300 are integrally formed, so that the overall structure of the brain protection device 10 is compact and firm, the stability of the arrangement is increased, and the protection effect is ensured. In one embodiment, the first filter sleeve 100, the deflector 200, and the second connector are integrally formed with the second filter sleeve 300. In one embodiment, the first support frame 110, the annular frame 220, the connecting frame 400 and the second support frame 310 are integrally cut and formed, so that the manufacturing process is simple, the overall structure is firmer and more stable, and the stability of the protection operation of the brain protection device 10 is ensured.

In one embodiment, as shown in FIG. 7, the first filter sleeve 100 includes a first woven sleeve 140 and a first filter membrane (not shown); the first woven sleeve 140 is a net structure, and the first woven sleeve 140 has the first opening 101; the first filtering membrane is disposed inside the first weaving sleeve 140 (note the modification described herein), and the outer wall surface of the first weaving sleeve 140 is configured to abut against the inner wall of the head arm stem 20, so that the first weaving sleeve 140 has smaller meshes than the first support frame 110 except for the first filtering membrane, and the intercepting and filtering effects of the first filtering sleeve 100 can be improved. In one embodiment, the material of the first braided sheath 140 includes one of nickel titanium and cobalt chromium.

In one embodiment, as shown in FIG. 7, the second filter sleeve 300 comprises a second woven sleeve 340 and a second filter membrane 320; the second woven sleeve 340 is a net structure, and the second woven sleeve 340 has the second opening 301; the second filtering membrane 320 is arranged inside the second woven cover 340 (note the modification described here), and the outer wall surface of the second woven cover 340 is used for abutting against the inner wall of the descending aorta 60, so that the second woven cover 340 has smaller meshes than the second support frame 310 except for the second filtering membrane 320, and the interception and filtering effects of the second filtering cover 300 can be improved. In one embodiment, the material of the second braided sleeve 340 includes one of nickel titanium and cobalt chromium.

In all embodiments of the present application, the terms "large" and "small" are relatively speaking, and the terms "upper" and "lower" are relatively speaking, so that descriptions of these relative terms are not repeated herein.

It should be appreciated that reference throughout this specification to "in this embodiment," "in an embodiment of the present application," or "in one of the embodiments" means that a particular feature, structure, or characteristic described in connection with the embodiment is included in at least one embodiment of the present application. Thus, the appearances of the phrases "in this embodiment," "in an embodiment of the present application," or "in one of the embodiments" in various places throughout this specification are not necessarily all referring to the same embodiment. Furthermore, the particular features, structures, or characteristics may be combined in any suitable manner in one or more embodiments. Those skilled in the art should also appreciate that the embodiments described in this specification are all alternative embodiments and that the acts and modules involved are not necessarily required for this application.

In various embodiments of the present application, it should be understood that the size of the serial number of each process described above does not mean that the execution sequence is necessarily sequential, and the execution sequence of each process should be determined by its function and inherent logic, and should not constitute any limitation on the implementation process of the embodiments of the present application.

The above description is only for the specific embodiments of the present application, but the scope of the present application is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present application, and shall be covered by the scope of the present application. Therefore, the protection scope of the present application shall be subject to the protection scope of the claims.

Claims

1. A brain protection device, comprising:

2. The brain protection device according to claim 1, comprising a connection frame, wherein the second filter sleeve is connected with the deflector through the connection frame, one end of the connection frame is connected with one end of the deflector far away from the first filter sleeve, and the other end of the connection frame is connected with the first end of the second filter sleeve.

3. The brain protection device of claim 2, wherein the connection frame is a closed structure.

4. The brain protection device according to claim 1, wherein the deflector comprises two deflector rods connected end to form an annular frame, and a deflector membrane fitted to an opening of the annular frame is provided in the annular frame; the deflector is used to cover the left common carotid artery and the left subclavian artery.

5. The brain protection device of claim 4, wherein a first end of a first one of the deflection conduits connects to a first end of a second one of the deflection conduits to form a first end point, a second end of the first one of the deflection conduits connects to a second end of the second one of the deflection conduits to form a second end point, the first end point forming a connection point to the first filter sleeve, and the second end point forming a connection point to the second filter sleeve.

6. The brain protection device according to claim 4, wherein the two deflection arms curve in an arc toward each other.

7. The brain protection device according to claim 1, wherein the first filter sleeve comprises a first support frame and a first filter membrane; the first support frame comprises a plurality of first support rods, every two first support rods are connected end to form a mesh, the first support frame is of a net structure, and the first support frame is provided with the first opening; the first filter membrane is arranged in the first support frame, and the outer wall surface of the first support frame is used for being abutted against the inner wall of the head arm.

8. The brain protection device according to claim 7, wherein the first filtering membrane has first filtering holes, and the pore size of the first filtering holes is 50-500 um.

9. The brain protection device of claim 1, wherein the second filter sleeve comprises a second scaffold and a second filter membrane; the second support frame comprises a plurality of second support rods, every two second support rods are connected end to form a mesh, the second support frame is of a net structure, and the second support frame is provided with a second opening; the second filtering membrane is arranged in the second supporting frame, and the outer wall surface of the second supporting frame is used for being abutted to the inner wall of the descending aorta.

10. The brain protection device according to claim 9, wherein the second filtering membrane has second filtering holes, and the pore size of the second filtering holes is 50-500 um.

11. The brain protection device of claim 1, wherein the first filter sleeve has a second end opposite the first end of the first filter sleeve, the second end of the first filter sleeve being provided with a first recovery member for detachable connection with an external recovery device that pierces into the head-arm stem.

12. The brain protection device of claim 11, wherein the first retrieval member comprises a first retrieval hook coupled to the second end of the first filter sleeve, the first retrieval hook configured to hook over an external loop that penetrates into the head-arm stem.

13. The brain protection device of claim 12, wherein the first recovery member comprises a hollow post coupled to the second end of the first filter cartridge, wherein a threaded connector is disposed within the hollow post for threaded connection with an external delivery device that is inserted into the brachiocephalic stem.

14. The brain protection device according to claim 13, wherein a portion of the hollow post is rotatably cut to form the first retrieval hook from an end of the hollow post connected to the first filter sleeve to an end of the hollow post distal from the first filter sleeve.

15. The brain protection device according to claim 1, wherein the second filter sleeve has a second end opposite the first end of the second filter sleeve, the second end of the second filter sleeve being provided with a second retrieval member for detachable connection with an external retrieval device for puncturing into the descending aorta.

16. The brain protection device according to claim 15, wherein the second retrieval member includes a second retrieval hook coupled to the second end of the second filtering sheath, the second retrieval hook for hooking an external loop that punctures into the descending aorta.

17. The brain protection device according to claim 16, wherein the second recovery hook comprises a connecting portion, a bending portion and a hooking portion which are connected in sequence, the connecting portion is connected with the second end of the second filter sleeve, and one end of the connecting portion, which is far away from the second filter sleeve, is connected with the bending portion; the connecting part extends along the length direction of the descending aorta, and the bending part and the connecting part form an included angle.

18. The brain protection device according to any one of claims 1 to 17, wherein the first filtering sleeve, the deflector and the second filtering sleeve are each of a collapsible construction, the first filtering sleeve, the deflector and the second filtering sleeve being collapsible into a delivery sheath for puncturing into the aortic arch, respectively.

19. The brain protection device of claim 18, wherein the material of the first filter sleeve, the material of the deflector, and the material of the second filter sleeve each comprise a shape memory material.

20. The brain protection device according to any one of claims 1 to 17, wherein the first filter sleeve, the deflector and the second filter sleeve are integrally formed.

21. The brain protection device according to claim 1, wherein the first filter sleeve comprises a first woven sleeve and a first filter membrane; the first woven sleeve is of a net structure and is provided with the first opening; the first filter membrane is arranged in the first woven sleeve, and the outer wall surface of the first woven sleeve is used for being abutted against the inner wall of the head arm stem.

22. The brain protection device of claim 1, wherein the second filter sleeve comprises a second woven sleeve and a second filter membrane; the second woven sleeve is of a net structure and is provided with the second opening; the second filtering membrane is arranged in the second weaving sleeve, and the outer wall surface of the second weaving sleeve is used for being abutted against the inner wall of the descending aorta.