CN114470535A - Boron neutron capture treatment beam line layout structure - Google Patents

Boron neutron capture treatment beam line layout structure Download PDF

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CN114470535A
CN114470535A CN202210068680.5A CN202210068680A CN114470535A CN 114470535 A CN114470535 A CN 114470535A CN 202210068680 A CN202210068680 A CN 202210068680A CN 114470535 A CN114470535 A CN 114470535A
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magnetic field
scanning magnet
proton
rotary scanning
beam spot
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CN114470535B (en
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魏素敏
管锋平
安世忠
贾先禄
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China Institute of Atomic of Energy
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China Institute of Atomic of Energy
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1077Beam delivery systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1085X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy characterised by the type of particles applied to the patient
    • A61N2005/1087Ions; Protons

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  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • General Health & Medical Sciences (AREA)
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Abstract

The invention discloses a boron neutron capture treatment beam line layout structure, which comprises: the device comprises a valve, a proton beam diagnostic device, a focusing element, a correcting element, an octopole lens, a rotary scanning magnet, a proton beam diagnostic device and vacuum equipment; the octupole lens is precisely matched with the rotary scanning magnet, the beam spot is adjusted from a small-area non-uniform beam spot into a small-area uniform beam spot, and then the beam spot is further expanded to a large-area uniform beam spot; the rotary scanning magnet and the beam pipeline respectively adopt a structure of combining a flange and an aluminum lining and combining stainless steel and the aluminum lining, and the beam streamline is a beam streamline with a closed-loop feedback loop; the invention enables the uniformity of the beam spot to reach more than 90%; the difference between theory and reality is adjusted in real time through a closed-loop magnetic field power supply loop; through changing the relative position relation of the rotary magnet and the beam pipeline, the eddy current heating problem of the beam pipeline is solved, and meanwhile, the radiation dose brought by particles bombarded on the pipeline is effectively reduced.

Description

Boron neutron capture treatment beam line layout structure
Technical Field
The invention belongs to the technical field of biology (medical treatment), and particularly relates to a beam line layout structure for boron neutron capture treatment.
Background
Boron Neutron Capture Therapy (BNCT) is one of the leading cancer target Therapy technologies in the international tumor Therapy field in recent years. The principle is that a medicine containing a non-radioactive boron isotope (boron-10) is used as a tumor positioning medicine and a neutron capture agent, and after the medicine is injected into a human body, a neutron beam generated by an accelerator for targeting is used for irradiating the tumor. The neutron beam and the boron isotope perform nuclear reaction to generate radioactive particles, so that the cancer cells can be destroyed accurately in the cancer cells, and normal tissues are not injured by mistake. BNCT technology has obvious curative effect on recurrent head and neck cancer, malignant cerebroma, melanin skin cancer and other tumors.
The accelerator generates a neutron beam, and the accelerator mainly generates high-current protons to bombard a specific target material. The transport of protons from the accelerator to the neutron target requires a beam transport line. Meanwhile, in order to increase the neutron yield, prolong the service life of the neutron target and prevent the neutron target from being damaged due to overheating, the beam current on the target needs to be homogenized as much as possible.
The difficulty in realizing beam homogenization is as follows: factors affecting the beam homogenization accuracy are manifold. One of the factors affecting accuracy: the cross section of the beam flowing through the focusing element by adopting the traditional method is in a Gaussian distribution state, namely: the beam near the center point of the beam cross section is very dense, and the edge beam is sparse, which is one of natural factors causing the beam cross section to be uneven; the second factor affecting accuracy: the conventional method employs a method of directly coupling a focusing element to a rotary magnet: the beam current flowing out of the focusing element is directly input to the rotary scanning magnet, although the rotary scanning magnet is arranged to spread the beam current according to a spiral track, an overlapping area exists between the beam current of the previous circle and the beam current of the next circle, due to the existence of Gaussian distribution, the beam current is not uniform even in the overlapping area, and therefore a large-area beam current area generated by the rotary magnet is not uniform along the radius direction; factor three affecting accuracy: the theoretical value and the actual value are often different, and because environmental factors influencing the change of the magnetic field are uncontrollable and real-time, the cross section of a beam spot actually generated by the rotary scanning magnet and the area of a preset beam spot of the rotary scanning magnet have dynamic difference, while the traditional method adopts an open-loop measurement method, real-time feedback and real-time adjustment cannot be realized, so that the uniformity of the beam current is influenced; four factors affecting accuracy: in the traditional method, a beam pipeline penetrates into a cylindrical rotary scanning magnet, in order to reduce the radiation dose when the beam penetrates through the beam pipeline, the beam pipeline is made of aluminum materials, the aluminum materials are easy to generate eddy currents and eddy currents to bring heating phenomena, the heating of the beam pipeline causes the change of magnetic field current, and the uniformity of the beam is also influenced.
Disclosure of Invention
The invention provides a boron neutron capture treatment beam streamline layout structure aiming at the problems in the prior art and aims to solve the problem of low beam uniformity accuracy caused by a traditional method.
The invention adopts the following technical scheme for solving the technical problems:
a boron neutron capture treatment beam line layout structure is disclosed, wherein a beam line is led out from an accelerator and leads to a proton treatment terminal; the beam line is sequentially provided with the following components along the direction led out from the accelerator: the device comprises a valve 1, a proton beam diagnostic device 2, proton beam focusing elements 3 and 4, a proton beam correcting element 5, an octopole lens 6, a rotary scanning magnet 7, a proton beam diagnostic device and vacuum equipment 8;
the valve 1 separates the accelerator from the proton beam transmission system, so that the two parts of vacuum systems are not interfered with each other; the diagnostic element 2 is used for monitoring the flow intensity, position and cross section of the protons; the focusing elements 3 and 4 are used to focus or defocus the beam stream; the element 5 is used for adjusting the beam current deviating from the center of the pipeline back; the octupole lens 6 is used for generating a small-sectional-area uniform beam spot; the rotary scanning magnet 7 is used for enabling the small-sectional-area uniform beam spot generated by the octupole lens 6 to rotationally hit the proton beam diagnostic device 8 along a spiral track, and finally forming a large-sectional-area uniform beam spot;
the method is characterized in that:
the octupole lens 6 is precisely matched with the rotary scanning magnet 7 to generate a uniform three-order gradient magnetic field and a periodically-changed magnetic field perpendicular to the proton beam, and the beam spot is adjusted from a small-area non-uniform beam spot to a small-area uniform beam spot and then further expanded to a large-area uniform beam spot;
the rotary scanning magnet 7 and the beam pipeline are respectively in a structure that a flange is combined with an aluminum lining and a stainless steel is combined with the aluminum lining, so that the heating phenomenon caused by eddy current generated by a rapidly-changing magnetic field is effectively prevented.
The beam streamline is a beam streamline with a closed-loop feedback loop: the focusing elements 3 and 4, the proton beam correction element 5, the octupole lens 6, the rotary scanning magnet 7 and the proton beam diagnostic device 8 form a closed loop feedback loop, and the closed loop feedback loop is provided with a magnetic field current control center.
The rotary scanning magnet 7 on the closed loop feedback loop drives the beam to a proton beam diagnostic device (8), the proton beam diagnostic device 8 feeds back the sectional area of the beam spot to a magnetic field current control center, the magnetic field current control center compares the sectional area with the predicted beam spot sectional area, and controls the focusing element 3, the 4 magnet power supply, the octopole lens 6 magnet power supply and the rotary scanning magnet 7 magnet power supply in sequence according to the difference value to adjust the respective magnetic field current, and drives the beam after adjusting the magnetic field current to the proton beam diagnostic device 8 again, and the proton beam diagnostic device 8 feeds back the beam spot sectional area to the magnetic field current control center again to circulate until the beam spot sectional area diagnosed by the proton beam diagnostic device 8 reaches the preset size.
The two ends of the rotary scanning magnet 7 are provided with flanges, the rotary scanning magnet 7 is connected with respective beam pipelines through the flanges at the two ends, and the inner wall of each beam pipeline is made of stainless steel, so that heating caused by eddy current generated by a rapidly-changing magnetic field is effectively prevented;
the rotary scanning magnet 7 and the inner wall of the beam pipeline are partially lined with aluminum, so that the radiation dose brought by particles bombarded on the pipeline is effectively reduced;
accurate matching is carried out between the respective magnetic field power supplies of the focusing elements 3 and 4, the octopole lens 6 and the rotary scanning magnet 7, and the method specifically comprises the following steps: the magnetic field power supply of the focusing elements 3 and 4 controls the focusing elements 3 and 4 to focus or defocus in the size range according to the diameter size requirement of focusing or defocusing; the magnetic field power supply of the octopole lens 6 controls the uniformity of the magnetic field within the size range according to the diameter requirements of the focusing elements 3 and 4; the magnetic field power supply of the rotary scanning magnet 7 controls the expansion angle of the spiral line and the overlapping area between two adjacent circles of uniform beam spots according to the size requirement of the uniform beam spots generated by the octupole lens 6.
The uniformity of the uniform beam spot generated by the octopole lens 6 reaches more than 90%, namely: the beam spot of the beam which extends outwards from the central point of the beam spot to not less than 90% of the circular area is a uniform beam spot.
When the uniform beam spots generated by the octupole lens 6 are hit on the proton beam diagnostic device 8 along the spiral track by the rotary scanning magnet 7, the overlapping area between two adjacent circles of uniform beam spots is less than 10%.
On the rotary scanning magnet 7 and the stainless steel beam flow pipeline inner wall, aluminium lining is partially added, namely: aluminum linings are added to the inner wall of the beam pipeline and the inner wall of the rotary scanning magnet 7 where the beam envelope is large, so that the radiation dose brought by particles bombarded on the pipeline at the position where the beam envelope is large is reduced.
Advantageous effects of the invention
1. The octupole lens is additionally arranged between the focusing element and the rotary scanning magnet, the octupole lens homogenizes the beam spots in Gaussian distribution, the uniformity of the beam spots is more than 90%, and further, the problem of homogenization of the beam spots is solved in advance before the beam enters the rotary magnet, the beam spots scanned by the rotary magnet are changed from large-area non-uniform beam spots into large-area uniform beam spots, and the bottleneck problem of low beam homogenization precision is solved.
2. The invention adjusts the theoretical and actual difference in real time and adjusts the problems of magnetic field change and low beam uniformity caused by uncontrollable environmental factors through a closed loop beam line magnetic field power supply loop.
3. The invention improves the assembly method of the rotary magnet and the beam pipeline, changes the relative position relation of the rotary magnet and the beam pipeline, and obtains unexpected effects: the method is characterized in that a rotary magnet is sleeved outside a beam pipeline in the traditional method, the improvement is that the rotary magnet is connected with the beam pipeline through flanges at two ends, and the rotary magnet is used as a part of the beam pipeline.
Drawings
FIG. 1 is a schematic diagram of a beam line layout for boron neutron capture therapy according to the present invention;
FIG. 2 is a schematic diagram of a beam line closed-loop magnetic field control loop according to the present invention;
in the figure, 1: a valve; 2: a proton beam diagnostic device; 3: a proton beam focusing element; 4: a proton beam focusing element; 5, a proton beam current correcting element; 6, an octopolar lens; 7, rotating the scanning magnet; 8, proton beam diagnostic device.
Detailed Description
The invention is further explained below with reference to the drawings in which:
the design principle of the invention is as follows:
the beam uniformity precision can be really improved only by organically combining all parts: factors affecting beam uniformity are manifold: the beam spots which are in Gaussian distribution and generated by the focusing element are the first reason for influencing the uniformity of the beam current, the theoretical difference and the actual difference caused by the uncontrollable environmental factors of the magnetic field are the second reason for influencing the uniformity of the beam current, and the beam current unevenness caused by the eddy heating of a beam current pipeline is the third reason for influencing the uniformity of the beam current. The invention adopts the combination of the eight-stage lens, the rotating magnet, the closed-loop magnetic field power supply control circuit and the method of adding the aluminum lining to the steel material to solve the problem of beam uniformity. The eight-stage lens changes the Gaussian beam spot into a beam spot with the uniformity of more than 90%, but the combination of the focusing element, the eight-stage lens and the rotary magnet only solves the problem of beam spot uniformity, and cannot solve the problem that the beam spot uniformity calculated theoretically is different from the actually measured beam spot uniformity due to the change of environmental factors, for example, the diameter of the focusing element cannot reach the preset diameter due to the disturbance of the environmental factors, the uniformity of the eight-stage lens randomly changes due to the disturbance of a magnetic field, the coverage range of the rotary magnet also changes due to the disturbance of the magnetic field, and the changes depend on the real-time monitoring and the real-time correction of a closed-loop magnetic field control loop to make up the difference; however, although the eight-stage lens solves the problem of beam spot uniformity and the magnetic field disturbance caused by environmental factors is overcome, however, if the problem of eddy current heating of the beam pipeline is not solved, new factors influencing beam uniformity can be generated, and the eddy current heating problem is solved, wherein the inner wall of the beam pipeline adopts stainless steel plus partial aluminum lining, the rotary magnet also adopts partial aluminum lining, but if the Gaussian distribution problem is not solved, the uniformity of the beam current still can not be ensured, and similarly, the closed-loop control circuit solves the problems of theoretical and practical differences and the problem of uneven beam current caused by eddy heating, but the Gaussian distribution causes uneven beam current, the fundamental problem is not solved, all the things are in vain, therefore, all the aspects can not exist independently, and all the aspects support and depend on each other, and the beam uniformity precision can be really improved only by combining the aspects.
Based on the principle, the invention designs a beam line layout structure for boron neutron capture treatment,
a boron neutron capture treatment beam line layout structure is shown in figures 1 and 2, and the beam line is led out from an accelerator and led to a proton treatment terminal; the beam line is sequentially provided with the following components along the direction led out from the accelerator: the device comprises a valve 1, a proton beam diagnostic device 2, proton beam focusing elements 3 and 4, a proton beam correcting element 5, an octopole lens 6, a rotary scanning magnet 7 and a proton beam diagnostic device 8;
the valve 1 separates the accelerator from the proton beam transmission system, so that the two parts of vacuum systems are not interfered with each other; the diagnostic element 2 is used for monitoring the flow intensity, position and cross section of the protons; the focusing elements 3 and 4 are used to focus or defocus the beam stream; the element 5 is used for adjusting the beam current deviating from the center of the pipeline back; the octupole lens 6 is used for generating a small-sectional-area uniform beam spot; the rotary scanning magnet 7 is used for enabling the small-sectional-area uniform beam spot generated by the octupole lens 6 to rotationally hit the proton beam diagnostic device 8 along a spiral track, and finally forming a large-sectional-area uniform beam spot;
the method is characterized in that:
the octupole lens 6 is precisely matched with the rotary scanning magnet 7 to generate a uniform three-order gradient magnetic field and a periodically-changed magnetic field perpendicular to the proton beam, and the beam spot is adjusted from a small-area non-uniform beam spot to a small-area uniform beam spot and then further expanded to a large-area uniform beam spot;
the rotary scanning magnet 7 and the beam pipeline are respectively in a structure that a flange is combined with an aluminum lining and a stainless steel is combined with the aluminum lining, so that the heating phenomenon caused by eddy current generated by a rapidly-changing magnetic field is effectively prevented.
The beam streamline is a beam streamline with a closed-loop feedback loop: the focusing elements 3 and 4, the proton beam correction element 5, the octupole lens 6, the rotary scanning magnet 7 and the proton beam diagnostic device 8 form a closed loop feedback loop, and the closed loop feedback loop is provided with a magnetic field current control center.
The rotary scanning magnet 7 on the closed loop feedback loop drives the beam to a proton beam diagnostic device (8), the proton beam diagnostic device 8 feeds back the sectional area of the beam spot to a magnetic field current control center, the magnetic field current control center compares the sectional area with the predicted beam spot sectional area, and controls the focusing element 3, the 4 magnet power supply, the octopole lens 6 magnet power supply and the rotary scanning magnet 7 magnet power supply in sequence according to the difference value to adjust the respective magnetic field current, and drives the beam after adjusting the magnetic field current to the proton beam diagnostic device 8 again, and the proton beam diagnostic device 8 feeds back the beam spot sectional area to the magnetic field current control center again to circulate until the beam spot sectional area diagnosed by the proton beam diagnostic device 8 reaches the preset size.
The two ends of the rotary scanning magnet 7 are provided with flanges, the rotary scanning magnet 7 is connected with respective beam pipelines through the flanges at the two ends, and the inner wall of each beam pipeline is made of stainless steel, so that heating caused by eddy current generated by a rapidly-changing magnetic field is effectively prevented;
the rotary scanning magnet 7 and the inner wall of the beam pipeline are partially lined with aluminum, so that the radiation dose brought by particles bombarded on the pipeline is effectively reduced;
accurate matching is carried out between the respective magnetic field power supplies of the focusing elements 3 and 4, the octopole lens 6 and the rotary scanning magnet 7, and the method specifically comprises the following steps: the magnetic field power supply of the focusing elements 3 and 4 controls the focusing elements 3 and 4 to focus or defocus in the size range according to the diameter size requirement of focusing or defocusing; the magnetic field power supply of the octopole lens 6 controls the uniformity of the magnetic field within the size range according to the diameter requirements of the focusing elements 3 and 4; the magnetic field power supply of the rotary scanning magnet 7 controls the expansion angle of the spiral line and the overlapping area between two adjacent circles of uniform beam spots according to the size requirement of the uniform beam spots generated by the octupole lens 6.
The uniformity of the uniform beam spot generated by the octopole lens 6 reaches more than 90%, namely: the beam spot of the beam which extends outwards from the central point of the beam spot to not less than 90% of the circle area is a uniform beam spot.
When the uniform beam spots generated by the octupole lens 6 are hit on the proton beam diagnostic device 8 along the spiral track by the rotary scanning magnet 7, the overlapping area between two adjacent circles of uniform beam spots is less than 10%.
On the rotary scanning magnet 7 and the stainless steel beam flow pipeline inner wall, aluminium lining is partially added, namely: aluminum linings are added to the inner wall of the beam pipeline and the inner wall of the rotary scanning magnet 7 where the beam envelope is large, so that the radiation dose brought by particles bombarded on the pipeline at the position where the beam envelope is large is reduced.
It should be emphasized that the above-described embodiments are merely illustrative of the present invention and are not limiting, since modifications and variations of the above-described embodiments, which are not inventive, may occur to those skilled in the art upon reading the specification, are possible within the scope of the appended claims.

Claims (8)

1. A boron neutron capture treatment beam line layout structure is disclosed, wherein a beam line is led out from an accelerator and leads to a proton treatment terminal; the beam line is sequentially provided with the following components along the direction led out from the accelerator: the device comprises a valve (1), a proton beam diagnostic device (2), proton beam focusing elements (3) and (4), a proton beam correcting element (5), an octopole lens (6), a rotary scanning magnet (7) and a proton beam diagnostic device (8);
the accelerator and the proton beam transmission system are separated by the valve (1), so that the two parts of vacuum systems are not interfered with each other; the diagnostic element (2) is used for monitoring the flow intensity, position and cross section of the protons; the focusing elements (3) and (4) are used for focusing or defocusing the beam flow; the element (5) is used for adjusting the beam current deviating from the center of the pipeline back; the octupole lens (6) is used for generating a uniform beam spot with a small sectional area; the rotary scanning magnet (7) is used for enabling the small-sectional-area uniform beam spot generated by the octupole lens (6) to rotationally hit the proton beam diagnostic device (8) along a spiral track, and finally forming a large-sectional-area uniform beam spot;
the method is characterized in that:
the octupole lens (6) is precisely matched with the rotary scanning magnet (7) to generate a uniform three-order gradient magnetic field and a periodically-changed magnetic field perpendicular to the proton beam, and the beam spot is adjusted from a small-area non-uniform beam spot to a small-area uniform beam spot and further expanded to a large-area uniform beam spot;
the rotary scanning magnet (7) and the beam pipeline are respectively in a structure of combining a flange with an aluminum lining and combining stainless steel with the aluminum lining, so that the heating phenomenon caused by eddy current generated by a rapidly-changing magnetic field is effectively prevented;
the beam streamline is a beam streamline with a closed-loop feedback loop: the focusing elements (3) and (4), the proton beam correction element (5), the octupole lens (6), the rotary scanning magnet (7) and the proton beam diagnostic device (8) form a closed loop feedback loop, and the closed loop feedback loop is provided with a magnetic field current control center.
2. The boron neutron capture treatment beam line layout structure of claim 1, wherein: and a rotating scanning magnet (7) on the closed loop feedback loop is used for feeding back the beam to a proton beam diagnostic device (8), the proton beam diagnostic device (8) feeds back the sectional area of the beam spot to a magnetic field current control center, the magnetic field current control center compares the sectional area with the predicted beam spot sectional area, sequentially controls a focusing element (3) and a focusing element (4), a magnet power supply of the octopole lens (6) and a magnet power supply of the rotating scanning magnet (7) to adjust the respective magnetic field current according to the difference, and feeds the beam after adjusting the magnetic field current back to the proton beam diagnostic device (8), and the proton beam diagnostic device (8) feeds back the beam spot sectional area to the magnetic field current control center again and repeats the operation until the beam spot sectional area diagnosed by the proton beam diagnostic device (8) reaches the preset size.
3. The boron neutron capture treatment beam line layout structure of claim 1, wherein: the two ends of the rotary scanning magnet (7) are provided with flanges, the rotary scanning magnet (7) is connected with respective beam pipelines through the flanges at the two ends, and the inner wall of each beam pipeline is made of stainless steel, so that heating caused by eddy current generated by a rapidly-changing magnetic field is effectively prevented.
4. The boron neutron capture treatment beam line layout structure of claim 1, wherein: the rotary scanning magnet (7) and the inner wall of the stainless steel flow pipe are partially lined with aluminum, so that the radiation dose brought by particles bombarded on the pipe is effectively reduced.
5. The boron neutron capture treatment beam line layout structure of claim 1, wherein: accurate matching is carried out between respective magnetic field power supplies of the focusing elements (3) and (4), the octupole lens (6) and the rotary scanning magnet (7), and the method specifically comprises the following steps: the magnetic field power supply of the focusing elements (3) and (4) controls the focusing elements (3) and (4) to focus or defocus in the size range according to the diameter size requirement of focusing or defocusing; the magnetic field power supply of the octupole lens (6) controls the uniformity of the magnetic field within the size range according to the diameter requirements of the focusing elements (3) and (4); the magnetic field power supply of the rotary scanning magnet (7) controls the expansion angle of the spiral line and the overlapping area between two adjacent circles of uniform beam spots according to the size requirement of the uniform beam spots generated by the octupole lens (6).
6. The boron neutron capture treatment beam line layout structure of claim 1, wherein: the uniformity of the uniform beam spot generated by the octupole lens (6) reaches more than 90 percent, namely: the beam spot of the beam which extends outwards from the central point of the beam spot to not less than 90% of the circle area is a uniform beam spot.
7. The boron neutron capture treatment beam line layout structure of claim 1, wherein: when the uniform beam spots generated by the octupole lens (6) are hit on the proton beam diagnostic device (8) along the spiral track by the rotary scanning magnet (7), the overlapping area between two adjacent circles of uniform beam spots is less than 10%.
8. The boron neutron capture treatment beam line layout structure of claim 1, wherein: on the rotary scanning magnet (7) and the stainless steel beam flow pipeline inner wall, aluminum lining is partially added, namely: aluminum linings are added to the inner wall of the beam pipeline and the inner wall of the rotary scanning magnet (7) where the beam envelope is large, so that the radiation dose brought by particles bombarded on the pipeline at the position where the beam envelope is large is reduced.
CN202210068680.5A 2022-01-20 2022-01-20 Boron neutron capture treatment beam line layout structure Active CN114470535B (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101778528A (en) * 2010-03-09 2010-07-14 中国原子能科学研究院 Method and device for high homogenization of beam current
CN105992449A (en) * 2015-02-26 2016-10-05 李晓粉 Beam leading-out device of accelerator
CN106075748A (en) * 2016-07-29 2016-11-09 中国原子能科学研究院 Wobbling magnet diffusion proton beam is utilized to carry out the method and device of oncotherapy
CN106139420A (en) * 2016-07-29 2016-11-23 中国原子能科学研究院 Proton therapy system based on cyclotron
CN206674289U (en) * 2017-03-31 2017-11-24 中国科学院高能物理研究所 A kind of new magnet for line homogenization

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101778528A (en) * 2010-03-09 2010-07-14 中国原子能科学研究院 Method and device for high homogenization of beam current
CN105992449A (en) * 2015-02-26 2016-10-05 李晓粉 Beam leading-out device of accelerator
CN106075748A (en) * 2016-07-29 2016-11-09 中国原子能科学研究院 Wobbling magnet diffusion proton beam is utilized to carry out the method and device of oncotherapy
CN106139420A (en) * 2016-07-29 2016-11-23 中国原子能科学研究院 Proton therapy system based on cyclotron
CN206674289U (en) * 2017-03-31 2017-11-24 中国科学院高能物理研究所 A kind of new magnet for line homogenization

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