CN114469219A - Absorbable/biodegradable implant for surgical operation and manufacturing method thereof - Google Patents
Absorbable/biodegradable implant for surgical operation and manufacturing method thereof Download PDFInfo
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- CN114469219A CN114469219A CN202210065067.8A CN202210065067A CN114469219A CN 114469219 A CN114469219 A CN 114469219A CN 202210065067 A CN202210065067 A CN 202210065067A CN 114469219 A CN114469219 A CN 114469219A
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- 239000007943 implant Substances 0.000 title claims abstract description 50
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 9
- 239000000463 material Substances 0.000 claims abstract description 23
- 239000002131 composite material Substances 0.000 claims abstract description 17
- 239000000835 fiber Substances 0.000 claims abstract description 12
- -1 polypropylene Polymers 0.000 claims abstract description 12
- 229920000728 polyester Polymers 0.000 claims abstract description 10
- 239000004743 Polypropylene Substances 0.000 claims abstract description 6
- 229920001610 polycaprolactone Polymers 0.000 claims abstract description 6
- 239000004632 polycaprolactone Substances 0.000 claims abstract description 6
- 239000004626 polylactic acid Substances 0.000 claims abstract description 6
- 229920000642 polymer Polymers 0.000 claims abstract description 6
- 229920001155 polypropylene Polymers 0.000 claims abstract description 6
- 229920001343 polytetrafluoroethylene Polymers 0.000 claims abstract description 6
- 239000004810 polytetrafluoroethylene Substances 0.000 claims abstract description 6
- 150000002148 esters Chemical class 0.000 claims abstract description 4
- 229920000747 poly(lactic acid) Polymers 0.000 claims abstract description 4
- 229920002463 poly(p-dioxanone) polymer Polymers 0.000 claims abstract description 4
- 229920001748 polybutylene Polymers 0.000 claims abstract description 4
- 239000000622 polydioxanone Substances 0.000 claims abstract description 4
- 239000004699 Ultra-high molecular weight polyethylene Substances 0.000 claims abstract 2
- 229920000785 ultra high molecular weight polyethylene Polymers 0.000 claims abstract 2
- 238000009954 braiding Methods 0.000 claims description 10
- 238000009941 weaving Methods 0.000 claims description 10
- 238000010276 construction Methods 0.000 claims description 8
- 239000003086 colorant Substances 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 7
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- 238000009940 knitting Methods 0.000 claims description 4
- 229920002678 cellulose Polymers 0.000 claims description 3
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- 238000010008 shearing Methods 0.000 abstract description 6
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- KUBDPQJOLOUJRM-UHFFFAOYSA-N 2-(chloromethyl)oxirane;4-[2-(4-hydroxyphenyl)propan-2-yl]phenol Chemical compound ClCC1CO1.C=1C=C(O)C=CC=1C(C)(C)C1=CC=C(O)C=C1 KUBDPQJOLOUJRM-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
- A61B17/06166—Sutures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
- A61L17/06—At least partially resorbable materials
- A61L17/10—At least partially resorbable materials containing macromolecular materials
- A61L17/105—Polyesters not covered by A61L17/12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
- A61L17/06—At least partially resorbable materials
- A61L17/10—At least partially resorbable materials containing macromolecular materials
- A61L17/12—Homopolymers or copolymers of glycolic acid or lactic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00004—(bio)absorbable, (bio)resorbable, resorptive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00526—Methods of manufacturing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
- A61B17/06166—Sutures
- A61B2017/06171—Sutures helically or spirally coiled
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Materials Engineering (AREA)
- Vascular Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Materials For Medical Uses (AREA)
Abstract
The invention provides an absorbable/biodegradable implant for surgical operation and a manufacturing method thereof, belonging to the technical field of medical textile instruments. The absorbable/biodegradable surgical implant is a composite structure, in particular consisting of a first fibrous braided core and a shell braided from a second fibrous; the first fiber is nonabsorbable/biodegradable material, and is selected from one or more of polyester, polypropylene, polytetrafluoroethylene, polybutylene ester and ultrahigh molecular weight polyethylene; the second fiber is absorbable/biodegradable material, and is selected from one or more of polylactic acid, polyglycolide-lactide polymer, polycaprolactone, polydioxanone and polyhydroxyalkyl polyester. The shell can avoid the phenomenon of stress concentration and reduce the shearing and tearing of the tissue; after the shell is absorbed or biodegraded, the tissue also gradually heals, at which point the required tensile strength is reduced, no stress concentration occurs, and the core can still provide sufficient strength to remain stable.
Description
Technical Field
The invention relates to the technical field of medical textile instruments, in particular to an absorbable/biodegradable implant for surgical operation and a manufacturing method thereof.
Background
As a surgical implant, the orthopedic suture is a common medical consumable and is widely applied to the occasions of wound suturing, tissue ligation, joint and implant fixation, soft tissue repair and the like. Compared with the common surgical suture, the orthopedic suture has higher performance requirements. The ideal orthopedic suture line can achieve the best in three aspects of mechanical property, operability and biological property, and specifically comprises the advantages of larger tensile strength, convenient distinguishing and knotting of appearance, smaller tissue shearing and foreign body reaction after being implanted into a human body and the like. At present, the related products of the orthopedic surgery suture line clinically used in China almost all depend on import, so that the surgery cost of a patient is high, and the technical monopoly is not beneficial to the development of related medical appliance industry in China.
Firstly, regarding the selection of raw materials, with the progress of chemistry and material industry, different kinds of absorbable and non-absorbable artificial synthetic raw materials are developed to produce various novel suture threads, but each material has certain weakness, and research is also dedicated to develop suture threads integrating the advantages of various raw materials. The method is usually realized by multi-component spinning, mixed weaving, surface coating and the like, high time cost and economic cost are required for research and development, and the effect of the final product is difficult to keep stable.
At present, the common structure of the orthopedic suture is a braided wire, most of the orthopedic suture is a circular section, and due to the small contact area between the shape and the tissue, the orthopedic suture is easy to generate stress concentration after being implanted, so that the tissue is cut or torn. In contrast, a flat suture reduces stress concentration, but larger knots are likely to form in the knotted portion of the flat suture, which tends to cause more intense post-operative discomfort.
Disclosure of Invention
Aiming at the defects in the prior art, the invention provides an absorbable/biodegradable implant for surgical operation and a manufacturing method thereof, aiming at solving the problem of stress concentration after the implant is implanted into organs and tissues in human bodies or animal bodies, relieving the contradiction between high tensile strength and degradable absorbable performance, namely realizing the purposes of providing higher tensile strength, reducing the stress concentration phenomenon generated after the surgical implant is stressed and promoting the tissue repair to a certain extent.
The invention is realized by the following technical scheme:
in one aspect, there is provided an absorbable/biodegradable surgical implant, which is a composite structure, in particular consisting of a first fibrous braided core and a shell braided by a second fibrous, the shell thread connecting the core and wrapping outside the core;
wherein the first cellulose is a non-absorbable/biodegradable material, and is selected from one or more of Polyester (PET), polypropylene (PP), Polytetrafluoroethylene (PTFE), polybutylene ester (PB) and ultrahigh molecular weight polyethylene (UHMWPE);
the second fiber is an absorbable/biodegradable material, and is selected from one or more of polylactic acid (PLA), polyglycolide-lactide Polymer (PGLA), Polycaprolactone (PCL), Polydioxanone (PDS) and polyhydroxyalkyl Polyester (PHA).
In one or more embodiments, the resorbable/biodegradable surgical implant is in the form of a braided suture.
In one or more embodiments, the first cellulosic braided core is a circular braid construction.
In one or more embodiments, the circular braid configuration has a cross-sectional diameter in a range of 0.250mm to 0.850 mm.
In one or more embodiments, the shell braided from the second cellulosic material is a flat braid construction.
In one or more embodiments, the flat braid configuration has a cross-sectional width in a range of 1.0mm to 5.0 mm.
In one or more embodiments, the first and second fibrous materials are comprised of monofilaments or multifilaments.
In one or more embodiments, the monofilaments have a diameter in the range of 0.05mm to 0.2mm and the multifilament yarns have a thickness in the range of 20D to 600D.
In one or more embodiments, the color of the monofilaments and multifilaments are provided in a plurality of different colors to provide identification for the surgeon to distinguish during the surgery.
In another aspect, there is provided a method of making the absorbable/biodegradable surgical implant described above, the method comprising: on the same knitting machine, first weaving a first fiber into a core, then connecting a second fiber with the core, and weaving into the shell, wherein the shell wire is connected with the core and wraps the outer side of the core; the braiding length of the core and the braiding length of the shell can be adjusted at will, and the braiding length of the shell is smaller than that of the core.
Compared with the prior art, the invention at least has the following beneficial effects:
1. the absorbable/biodegradable surgical implant provided by the invention is braided by using different raw material combinations, and the raw material proportion can be selected according to the use environment of the implant so as to adjust the degradation period of a suture line in a body.
2. The shell of the flat braided fabric structure is braided by using absorbable/biodegradable materials, the core of the circular braided fabric structure is braided by using non-absorbable/biodegradable materials, and the flat braided fabric structure can avoid the phenomenon of stress concentration and reduce the shearing and tearing of tissues at the initial use stage of the implant; the tissue also progressively heals after the absorbable/biodegradable shell is absorbed or biodegraded, at which point the required tensile strength is reduced, no stress concentration occurs, and the core of the circular braid configuration can still provide sufficient strength to remain stable.
3. After the operation, the absorbable/biodegradable shell is gradually degraded along with the healing of the growth of the tissues of the human body or the animal body, so that more space is provided for the growth of cells, and the postoperative repair is facilitated.
4. The manufacturing method of the absorbable/biodegradable implant for the surgical operation is simple and convenient, the implant with a composite structure can be completed on one medical knitting machine, the process is convenient to adjust, and the product has strong adjustability in thickness and length.
Of course, it is not necessary for any one product in which the invention is practiced to achieve all of the above-described technical effects simultaneously.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the principles of the invention and not to limit the invention. In the drawings:
FIG. 1 is an enlarged schematic view of an implant of composite construction according to an embodiment of the present invention;
FIG. 2 is an enlarged cross-sectional view of a core in an implant according to an embodiment of the present invention;
FIG. 3 is an enlarged cross-sectional view of a composite structure of an implant according to an embodiment of the present invention;
FIGS. 4-7 are enlarged structural views of the surface patterns of the implant according to the embodiment of the present invention, wherein the black and white colors represent yarns of different colors, respectively;
FIG. 8 is a schematic view showing the use of the implant for suturing human tissue according to an embodiment of the present invention.
Reference numerals:
1001. a second cellulosic knitted shell, 1002, shell to core connecting line, 1003, first cellulosic knitted core; 3001. the cross-section of the connecting line of the shell and the core, 3002, the yarn cross-section of the shell, 3003, the yarn cross-section of the core; 8001. human/animal body tissue, 8002, suture in contact with tissue with composite structure, 8003, core of circular braid construction, 8004, knot formed by the core.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The raw material sources used in the examples of the present invention may be purchased from commercial sources, unless otherwise specified.
First, the following explanation is made to terms referred to in the present invention:
surgical implant: implants (implantable medical devices) are implantable articles that are placed in a body cavity created by a surgical procedure or otherwise present physiologically.
The surgical implant according to the present invention may be implemented in the form of a hernia repair mesh, a surgical suture, etc. The following examples, which implement the surgical implant in the form of a surgical suture, are provided to clearly and completely describe the technical solution provided by the present invention.
The core referred to in the present invention means a central portion of the surgical implant, can be understood as an intermediate inner layer structure, and is generally implemented in a circular braid structure, and has a stable structure and high tensile strength.
The shell referred to in the present invention refers to the peripheral portion of the surgical implant, can be understood as a structure that does not completely wrap the core, and is generally implemented as a flat braid structure, increasing the contact area with the human/animal tissue, thereby avoiding the stress concentration phenomenon and reducing the occurrence of the tissue shearing and tearing.
In addition, it should be noted that the second fibrous material is an absorbable/biodegradable material, and the degradation cycle of the selected specific material in the human/animal body is known, for example: the strength of the PLA suture can be kept for 12 weeks after the PLA suture is implanted; PDS can be maintained for 20 weeks; if 50% of each of the two materials, PLA and PDS, is used, the degradation period is about 16 weeks. The degradation period can be set according to the degradation period of the known material in vivo, so as to meet the actual requirement.
Fig. 1 schematically shows an absorbable/biodegradable surgical implant according to the present invention, embodied as a braided suture, of composite construction, in particular consisting of a first fibrous braided core 1003 and a second fibrous braided shell 1001, said shell thread connecting and wrapping said core, in the figure 1002, the connecting line of "shell" to "core".
In this embodiment, the first cellulosic material is a non-absorbable/biodegradable material selected from Ultra High Molecular Weight Polyethylene (UHMWPE); of course, the tensile strength of the material can be referred to according to the use requirement, and the material can also be selected from one or more of Polyester (PET), polypropylene (PP), Polytetrafluoroethylene (PTFE) and polybutylene ester (PB).
In this embodiment, the second fibrous material is an absorbable/biodegradable material selected from polyglycolide-lactide Polymer (PGLA); of course, according to the use requirement, the period of the material absorption/biodegradation can be referred to, and one or more of polylactic acid (PLA), Polycaprolactone (PCL), Polydioxanone (PDS) and polyhydroxyalkyl Polyester (PHA) can be selected.
Fig. 2 exemplarily shows a cross-sectional enlarged structural view of the core woven from the first fibrous substance, and it can be seen that the core woven from the first fibrous substance is implemented in a circular braid configuration having a cross-sectional diameter ranging from 0.250mm to 0.850mm, and the present embodiment is implemented in 0.507 mm; the first fibrous mass consists of monofilaments or composite filaments, which in this embodiment are realized as multifilaments; the thickness range of the yarn is 20D-600D; further, the first cellulose in this embodiment is 8 strands of ultra-high molecular weight polyethylene (UHMWPE) multifilament with a thickness of 200D, wherein 1 strand is white multifilament, and 7 strands are blue multifilament, and different colors serve as markers for the convenience of differentiation during surgery of doctors.
Fig. 3 exemplarily shows a cross-sectional enlarged structural schematic view of the composite structure of the implant, from a section 3001 of the connecting line of the "shell" and the "core", a yarn section 3002 of the "shell", and a yarn section 3003 of the "core", in the figure, it can be seen that the second fibrous braided shell is implemented in a flat braid configuration having a cross-sectional width in the range of 1.0mm to 5.0mm, in the present embodiment, 1.5 mm; the second fiber is composed of single filaments or composite filaments, the embodiment is realized by the single filaments, and the diameter range of the single filaments is 0.05mm-0.2 mm; specifically, the second fibrous mass in this example employs 9 polyglycolide-lactide Polymer (PGLA) monofilaments having a diameter of 0.15 mm.
Fig. 4-7 schematically show enlarged views of the surface pattern of the implant, wherein the black and white colors represent yarns of different colors, respectively, which in this embodiment represent blue and white ultra-high molecular weight polyethylene (UHMWPE) multifilament yarns.
The absorbable/biodegradable surgical implant of the present embodiment is implemented in the form of a braided suture, and is manufactured by a process comprising:
weaving a first fiber into a core on the same weaving machine, and optionally weaving 8 strands of ultra-high molecular weight polyethylene (UHMWPE) multifilament with the thickness of 200D into a core with a circular woven fabric structure; a second fiber was then spliced to the core and braided into a sheath of flat braid construction, with sheath wires connecting the core and wrapping around the outside of the core, optionally, 9 strands of polyglycolide-lactide Polymer (PGLA) monofilament having a diameter of 0.15mm were spliced to the braided core and braided into a sheath, with a "sheath" wire connecting the "core" and wrapping around the outside of the "core". Alternatively, the braiding length of the core and the braiding length of the shell may be arbitrarily adjusted by the braiding time, and the braiding length of the shell is smaller than that of the core.
In embodiments of the present invention, the weaving pitch may be adjusted according to known weaving techniques to adjust the tightness of the woven surgical suture; the laminating mode of the yarns is adjusted to realize different patterns of the surgical suture line. In the embodiment of the invention, the absorbable/biodegradable surgical implant is a braided suture, wherein the core knotting tensile breaking strength of the round braided fabric structure is 163.89N according to a breaking strength test method in Chinese medical industry standard YY0167-2020 non-absorbable surgical suture; the shell of the flat braid structure and the core of the circular braid structure, i.e., the suture of the composite structure, both had an overall tensile breaking strength of 238.54N, which met the requirements of the suture strength standard.
In an embodiment of the invention, the braided composite structure has an overall absorbable/biodegradable suture length of 1200mm, with a flattened cross-sectional portion length of 400 mm.
Fig. 8 exemplarily shows that the absorbable/biodegradable suture of the composite structure provided by the embodiment of the present invention is applied to human/animal body tissue repair, the suture 8002 having the composite structure in contact with the tissue passes through the damaged portion of the human/animal body tissue 8001, the suture is pulled out, and the core 8003 of a circular braid configuration is implemented as a knot 8004 formed by the "core" during or at the completion of the surgery. It can be seen that the flat braided fabric structure can avoid the stress concentration phenomenon and reduce the occurrence of the shearing and tearing of the tissue, and compared with the braided suture line with a composite structure, the core of the circular braided fabric structure has the advantages of narrow line width, convenience in knotting and small formed knot.
In summary, the absorbable/biodegradable surgical implant provided by the embodiments of the present invention is woven by using different raw material combinations, and the raw material ratio can be selected according to the use environment of the implant, so as to adjust the degradation period of the suture in vivo. In the embodiment of the invention, the shell of the flat braided fabric structure is braided by using absorbable/biodegradable materials, the core of the circular braided fabric structure is braided by using non-absorbable/biodegradable materials, and the flat braided fabric structure can avoid the stress concentration phenomenon and reduce the shearing and tearing of tissues at the initial use stage of the implant; the tissue also progressively heals after the absorbable/biodegradable shell is absorbed or biodegraded, at which point the required tensile strength is reduced, no stress concentration occurs, and the core of the circular braid configuration can still provide sufficient strength to remain stable. After the operation, the absorbable/biodegradable shell is gradually degraded along with the healing of the growth of tissues of a human body or an animal body, so that more space is provided for the growth of cells, and the postoperative repair is facilitated. The manufacturing method of the absorbable/biodegradable implant for the surgical operation provided by the embodiment of the invention is simple and convenient, the implant with a composite structure can be completed on one medical knitting machine, the process is convenient to adjust, and the thickness and the length of the product can be adjusted according to requirements.
The foregoing descriptions of specific exemplary embodiments of the present invention have been presented for purposes of illustration and description. They are not intended to limit the invention to the precise forms disclosed, and obviously many modifications and variations are possible in light of the above teaching. The exemplary embodiments were chosen and described in order to explain certain principles of the invention and its practical application to enable one skilled in the art to make and use various exemplary embodiments of the invention and various alternatives and modifications as are suited to the particular use contemplated. It is intended that the scope of the invention be limited only by the claims and the equivalents thereof.
Claims (10)
1. An absorbable/biodegradable surgical implant, characterized in that it is a composite structure, in particular consisting of a first fibrous braided core and a shell braided by a second fibrous, the shell thread connecting the core and wrapping outside the core;
wherein the first cellulose is a non-absorbable/biodegradable material, and is selected from one or more of polyester, polypropylene, polytetrafluoroethylene, polybutylene ester and ultrahigh molecular weight polyethylene;
the second fiber is an absorbable/biodegradable material and is selected from one or more of polylactic acid, polyglycolide-lactide polymer, polycaprolactone, polydioxanone and polyhydroxyalkyl polyester.
2. The absorbable/biodegradable surgical implant of claim 1, wherein the absorbable/biodegradable surgical implant is in the form of a braided suture.
3. The absorbable/biodegradable surgical implant of claim 1, wherein the first fibrous braided core is a circular braid construction.
4. The absorbable/biodegradable surgical implant of claim 3, wherein the circular braid configuration has a cross-sectional diameter in the range of 0.250mm-0.850 mm.
5. The absorbable/biodegradable surgical implant of claim 1, wherein the shell braided from second fibers is a flat braid construction.
6. The absorbable/biodegradable surgical implant of claim 5, wherein the flat braid configuration has a cross-sectional width in a range of 1.0mm-5.0 mm.
7. The absorbable/biodegradable surgical implant of claim 1, wherein the first and second fibrous materials are comprised of monofilament or multifilament yarns.
8. The absorbable/biodegradable surgical implant of claim 7, wherein the monofilaments have a diameter in the range of 0.05mm to 0.2mm and the multifilaments have a thickness in the range of 20D to 600D.
9. The absorbable/biodegradable surgical implant of claim 7, wherein the color of the mono-or multifilament yarns is provided in a plurality of different colors to serve as indicia.
10. A method of making an absorbable/biodegradable surgical implant as claimed in any one of claims 1-9, wherein the method comprises: on the same knitting machine, first weaving a first fiber into a core, then connecting a second fiber with the core, and weaving into the shell, wherein the shell wire is connected with the core and wraps the outer side of the core; the braiding length of the core and the braiding length of the shell can be adjusted at will, and the braiding length of the shell is smaller than that of the core.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210065067.8A CN114469219A (en) | 2022-01-20 | 2022-01-20 | Absorbable/biodegradable implant for surgical operation and manufacturing method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210065067.8A CN114469219A (en) | 2022-01-20 | 2022-01-20 | Absorbable/biodegradable implant for surgical operation and manufacturing method thereof |
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| CN114469219A true CN114469219A (en) | 2022-05-13 |
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| CN202210065067.8A Pending CN114469219A (en) | 2022-01-20 | 2022-01-20 | Absorbable/biodegradable implant for surgical operation and manufacturing method thereof |
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Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111529752A (en) * | 2020-04-15 | 2020-08-14 | 东华大学 | Variable cross-section porous strip suture for promoting tendon healing and preparation method thereof |
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