CN114431509A - Electronic cigarette liquid with cough relieving effect - Google Patents
Electronic cigarette liquid with cough relieving effect Download PDFInfo
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- CN114431509A CN114431509A CN202210056764.7A CN202210056764A CN114431509A CN 114431509 A CN114431509 A CN 114431509A CN 202210056764 A CN202210056764 A CN 202210056764A CN 114431509 A CN114431509 A CN 114431509A
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- China
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- essential oil
- electronic cigarette
- cigarette liquid
- theanine
- sweet orange
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- 239000003571 electronic cigarette Substances 0.000 title claims abstract description 60
- 206010011224 Cough Diseases 0.000 title claims abstract description 33
- 239000007788 liquid Substances 0.000 title claims abstract description 33
- 230000000694 effects Effects 0.000 title claims abstract description 23
- 239000000341 volatile oil Substances 0.000 claims abstract description 94
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims abstract description 72
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 57
- DATAGRPVKZEWHA-YFKPBYRVSA-N N(5)-ethyl-L-glutamine Chemical compound CCNC(=O)CC[C@H]([NH3+])C([O-])=O DATAGRPVKZEWHA-YFKPBYRVSA-N 0.000 claims abstract description 52
- 235000006679 Mentha X verticillata Nutrition 0.000 claims abstract description 27
- 235000002899 Mentha suaveolens Nutrition 0.000 claims abstract description 27
- 235000001636 Mentha x rotundifolia Nutrition 0.000 claims abstract description 27
- 235000005976 Citrus sinensis Nutrition 0.000 claims abstract description 26
- 240000002319 Citrus sinensis Species 0.000 claims abstract description 26
- 229940026510 theanine Drugs 0.000 claims abstract description 26
- 235000011187 glycerol Nutrition 0.000 claims abstract description 23
- 244000276331 Citrus maxima Species 0.000 claims abstract description 22
- 235000001759 Citrus maxima Nutrition 0.000 claims abstract description 22
- 235000013311 vegetables Nutrition 0.000 claims abstract description 22
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 22
- XMGQYMWWDOXHJM-JTQLQIEISA-N (+)-α-limonene Chemical compound CC(=C)[C@@H]1CCC(C)=CC1 XMGQYMWWDOXHJM-JTQLQIEISA-N 0.000 claims description 16
- 238000003756 stirring Methods 0.000 claims description 12
- 238000000034 method Methods 0.000 claims description 4
- 244000269722 Thea sinensis Species 0.000 claims description 2
- 238000002156 mixing Methods 0.000 claims description 2
- 241000208125 Nicotiana Species 0.000 abstract description 15
- 235000002637 Nicotiana tabacum Nutrition 0.000 abstract description 15
- 230000000391 smoking effect Effects 0.000 abstract description 9
- 238000000889 atomisation Methods 0.000 abstract description 7
- 235000019640 taste Nutrition 0.000 abstract description 3
- 206010061218 Inflammation Diseases 0.000 abstract description 2
- 230000003467 diminishing effect Effects 0.000 abstract description 2
- 239000003205 fragrance Substances 0.000 abstract description 2
- 230000004054 inflammatory process Effects 0.000 abstract description 2
- 239000000779 smoke Substances 0.000 abstract description 2
- 210000002345 respiratory system Anatomy 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 21
- 239000000284 extract Substances 0.000 description 8
- 239000003814 drug Substances 0.000 description 6
- 235000019504 cigarettes Nutrition 0.000 description 4
- 230000000052 comparative effect Effects 0.000 description 4
- 206010036790 Productive cough Diseases 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 208000024794 sputum Diseases 0.000 description 3
- 210000003802 sputum Anatomy 0.000 description 3
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical class CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 description 2
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
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- 235000006200 Glycyrrhiza glabra Nutrition 0.000 description 2
- 241000699670 Mus sp. Species 0.000 description 2
- 244000131316 Panax pseudoginseng Species 0.000 description 2
- 235000003181 Panax pseudoginseng Nutrition 0.000 description 2
- 241000304195 Salvia miltiorrhiza Species 0.000 description 2
- 235000011135 Salvia miltiorrhiza Nutrition 0.000 description 2
- 235000011114 ammonium hydroxide Nutrition 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- HMUNWXXNJPVALC-UHFFFAOYSA-N 1-[4-[2-(2,3-dihydro-1H-inden-2-ylamino)pyrimidin-5-yl]piperazin-1-yl]-2-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)ethanone Chemical compound C1C(CC2=CC=CC=C12)NC1=NC=C(C=N1)N1CCN(CC1)C(CN1CC2=C(CC1)NN=N2)=O HMUNWXXNJPVALC-UHFFFAOYSA-N 0.000 description 1
- 241000205585 Aquilegia canadensis Species 0.000 description 1
- 244000012254 Canarium album Species 0.000 description 1
- 235000009103 Canarium album Nutrition 0.000 description 1
- 206010012335 Dependence Diseases 0.000 description 1
- 241001547127 Fritillaria cirrhosa Species 0.000 description 1
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 description 1
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 238000012449 Kunming mouse Methods 0.000 description 1
- 244000178870 Lavandula angustifolia Species 0.000 description 1
- 235000010663 Lavandula angustifolia Nutrition 0.000 description 1
- 241000234435 Lilium Species 0.000 description 1
- 235000014676 Phragmites communis Nutrition 0.000 description 1
- 244000274050 Platycodon grandiflorum Species 0.000 description 1
- 235000006753 Platycodon grandiflorum Nutrition 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 241001571446 Scaphium scaphigerum Species 0.000 description 1
- 244000185386 Thladiantha grosvenorii Species 0.000 description 1
- 235000011171 Thladiantha grosvenorii Nutrition 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000954 anitussive effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 230000000711 cancerogenic effect Effects 0.000 description 1
- 231100000315 carcinogenic Toxicity 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 description 1
- 230000005802 health problem Effects 0.000 description 1
- 235000012907 honey Nutrition 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000009776 industrial production Methods 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 239000001102 lavandula vera Substances 0.000 description 1
- 235000018219 lavender Nutrition 0.000 description 1
- 229940010454 licorice Drugs 0.000 description 1
- 235000011477 liquorice Nutrition 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 235000019659 mouth feeling Nutrition 0.000 description 1
- 210000003928 nasal cavity Anatomy 0.000 description 1
- 229960002715 nicotine Drugs 0.000 description 1
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 description 1
- 210000001331 nose Anatomy 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 239000010664 perilla essential oil Substances 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 210000003437 trachea Anatomy 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/10—Chemical features of tobacco products or tobacco substitutes
- A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
- A24B15/167—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
- A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
- A24B15/302—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances by natural substances obtained from animals or plants
- A24B15/303—Plant extracts other than tobacco
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Botany (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
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- Medical Informatics (AREA)
- Agronomy & Crop Science (AREA)
- Toxicology (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention provides an electronic cigarette liquid with a cough relieving effect, which comprises pummelo peel essential oil, sweet orange essential oil, mint essential oil, theanine, propylene glycol and vegetable glycerin in a specific ratio. According to the invention, the natural essential oil pummelo peel essential oil, sweet orange essential oil and mint essential oil are selected to compound theanine, and the natural essential oil pummelo peel essential oil, sweet orange essential oil and mint essential oil can stably volatilize along with a fuming agent at a conventional atomization temperature, enter a respiratory tract through smoke, directly act on the respiratory tract, and play roles in relieving cough, moistening throat, diminishing inflammation and preserving moisture. The electronic cigarette liquid does not contain tobacco components, tastes soft and soft, has natural fragrance, and is high in smoking comfort and pleasure.
Description
Technical Field
The invention relates to the technical field of electronic cigarettes, in particular to electronic cigarette liquid with a cough relieving effect.
Background
The electronic cigarette changes liquid into steam through the atomizer, and the atomization generates smoke feeling. Compared with the traditional cigarette, the electronic cigarette reduces the harm degree to the body to a certain extent. However, the conventional electronic cigarette mainly uses nicotine salt and other components as additives, and still causes certain addiction and health problems.
In addition, in order to improve the efficacy of the electronic cigarette in moistening throat, relieving cough and reducing sputum, and the like, electronic cigarettes added with some traditional Chinese medicine extracts are proposed at present. For example, patent document CN105146729A discloses an electronic cigarette tobacco tar with cough relieving and throat moistening functions, which is composed of the following components: plant nicotine, propylene glycol, pure water, loquat extract, pseudo-ginseng extract, salvia miltiorrhiza extract and bulbus fritilariae extract. The electronic cigarette tobacco tar with the functions of relieving cough and moistening the throat and relieving smoking harm is formed by adding extracts of loquat, pseudo-ginseng, salvia miltiorrhiza, bulbus fritilariae and the like into the tobacco tar and combining with modern science and technology, the electronic cigarette tobacco tar does not contain tar and other carcinogenic components in traditional cigarettes, the effects of controlling blood pressure of a human body and relieving cough and moistening the throat can be achieved while a user smokes, and smoking harm is effectively relieved. Patent document CN106036991A discloses an electronic cigarette tobacco tar with lung-heat clearing and throat moistening effects and a preparation method thereof, the electronic cigarette tobacco tar comprises a base solution and a traditional Chinese medicine extracting solution, the base solution comprises propylene glycol and glycerol, the traditional Chinese medicine used in the traditional Chinese medicine extracting solution is one or more selected from momordica grosvenori, platycodon grandiflorum, lily, scaphium scaphigerum, mint, fritillaria cirrhosa, dried orange peel, honey, liquorice, honeysuckle, reed rhizome and Chinese olive, and the electronic cigarette tobacco tar has certain health care effects of lung-heat clearing and throat moistening, antibiosis, inflammation diminishing, cough relieving and phlegm reducing and the like.
However, because the atomization temperature of the electronic cigarette is low, the traditional Chinese medicine extract added in the cigarette oil of the electronic cigarette cannot be effectively volatilized substantially at the heating temperature of the electronic cigarette, so that the effective components are only gathered in the cigarette cartridge of the electronic cigarette and cannot be in substantial contact with the human body in the smoking process, thereby affecting the function of the electronic cigarette. Meanwhile, the tobacco tar prepared by the traditional Chinese medicine extract has poor taste and affects the atomization efficiency of the electronic cigarette.
Disclosure of Invention
Based on this, there is a need for an electronic cigarette liquid with cough relieving effect, which does not affect the atomization efficiency of the electronic cigarette, has soft taste, and significantly enhances the smoking comfort.
The invention adopts the following technical scheme:
the invention provides an electronic cigarette liquid with a cough relieving effect, which is mainly prepared from the following components: pummelo peel essential oil, sweet orange essential oil, mint essential oil, theanine, water, propylene glycol and vegetable glycerin; wherein the volume ratio of the pummelo peel essential oil, the sweet orange essential oil, the mint essential oil, the water, the propylene glycol and the vegetable glycerin is (1-10), (1-5), (1-15), (5-12), (2-40) and (40-60).
In some embodiments, the volume ratio of the pummelo peel essential oil, the sweet orange essential oil, the mint essential oil, the water, the propylene glycol and the vegetable glycerin is (4-6): 1-3): 6-10): 5-12): 20-40): 40-60.
In some embodiments, the volume ratio of the pummelo peel essential oil, the sweet orange essential oil, the mint essential oil, the water, the propylene glycol and the vegetable glycerin is 5:2:10:10 (20-25) to (40-60).
In some embodiments, the concentration of theanine is 5-10 mg/mL.
In some of these embodiments, the concentration of theanine is 8 mg/mL.
In some of these embodiments, the exocarpium Citri Grandis essential oil is pure exocarpium Citri Grandis essential oil with D-limonene content of no less than 96%.
In some of these embodiments, the theanine is theanine extracted from natural tea leaves. The mint essential oil is natural mint essential oil, and the sweet orange essential oil is sweet orange pure essential oil.
The invention also provides a preparation method of the electronic cigarette liquid with the cough relieving effect, which comprises the following steps: mixing exocarpium Citri Grandis essential oil, fructus Citri sinensis essential oil, herba Menthae essential oil, theanine, water, propylene glycol and vegetable glycerol, and stirring.
The electronic cigarette comprises the electronic cigarette liquid.
Compared with the prior art, the invention has the beneficial effects that:
(1) according to the invention, the electronic cigarette is innovatively used as a carrier, and the pummelo peel essential oil, the sweet orange essential oil, the mint essential oil in a specific type and proportion are compounded with theanine, water, propylene glycol and vegetable glycerin as main components of the electronic cigarette tobacco tar to prepare the novel electronic cigarette tobacco tar, so that the novel electronic cigarette tobacco tar can be changed into gas along with the heating of the tobacco tar at the heating temperature of the electronic cigarette, has high atomization efficiency, and can be absorbed and exerted by an organism after contacting with the trachea and the nasal cavity of the organism in the process of being sucked. The comfortable smoking feeling of smokers can be met, the mouth feeling is good, and the effects of freeing the nose, moistening the throat and relieving cough are achieved.
(2) The electronic cigarette liquid does not contain tobacco components and any essence, has small harm to health, has the effects of relieving cough and moistening throat, and can obviously improve cough and throat dryness and itching caused by cold and diet. Meanwhile, the natural plant essential oil is adopted, so that the mouth feel is soft, the natural fragrance is realized, and the smoking comfort and pleasure are strong.
(3) The electronic cigarette liquid with the effects of relieving cough and reducing sputum, provided by the invention, is simple in preparation method and suitable for industrial production.
Detailed Description
The present invention is further described in detail below with reference to specific examples so that those skilled in the art can more clearly understand the present invention.
The following examples are provided only for illustrating the present invention and are not intended to limit the scope of the present invention. All other embodiments obtained by a person skilled in the art based on the specific embodiments of the present invention without any creative work belong to the protection scope of the present invention.
In the examples of the present invention, all the raw material components are commercially available products well known to those skilled in the art, unless otherwise specified; in the examples of the present invention, unless otherwise specified, all technical means used are conventional means well known to those skilled in the art.
The essential oils used in this experiment were all undiluted pure essential oils.
Test examples 1-1
The test example provides an electronic cigarette liquid, which is prepared by uniformly stirring the following components at a high speed: 1 volume part of pummelo peel essential oil (the content of D-limonene is not less than 96 percent), 1 volume part of sweet orange essential oil, 5 volume parts of mint essential oil, 5 volume parts of water, 38 volume parts of propylene glycol, 50 volume parts of vegetable glycerol and 5mg/mL of theanine.
Test examples 1 to 2
The test example provides an electronic cigarette liquid which is prepared by uniformly stirring the following components at a high speed: 3 parts by volume of pummelo peel essential oil (the content of D-limonene is not less than 96 percent), 2 parts by volume of sweet orange essential oil, 10 parts by volume of mint essential oil, 10 parts by volume of water, 25 parts by volume of propylene glycol, 50 parts by volume of vegetable glycerol and 8mg/mL of theanine.
Test examples 1 to 3
The test example provides an electronic cigarette liquid, which is prepared by uniformly stirring the following components at a high speed: 5 parts by volume of pummelo peel essential oil (the content of D-limonene is not less than 96 percent), 2 parts by volume of sweet orange essential oil, 10 parts by volume of mint essential oil, 10 parts by volume of water, 23 parts by volume of propylene glycol, 50 parts by volume of vegetable glycerol and 8mg/mL of theanine.
Test example 2-1
The comparative example provides an electronic cigarette liquid which is prepared by uniformly stirring the following components at a high speed: 2 parts by volume of sweet orange essential oil, 10 parts by volume of mint essential oil, 10 parts by volume of water, 23 parts by volume of propylene glycol, 50 parts by volume of vegetable glycerol and 8mg/mL of theanine. Compared with the experimental examples 1-3, the essential oil of pummelo peel is not contained.
Test examples 2 to 2
The comparative example provides an electronic cigarette liquid, which is prepared by uniformly stirring the following components at a high speed: 5 parts by volume of pummelo peel essential oil (the content of D-limonene is not less than 96 percent), 10 parts by volume of mint essential oil, 10 parts by volume of water, 23 parts by volume of propylene glycol, 50 parts by volume of vegetable glycerol and 8mg/mL of theanine. Compared with the experimental examples 1-3, the orange essential oil is not contained.
Test examples 2 to 3
The comparative example provides an electronic cigarette liquid, which is prepared by uniformly stirring the following components at a high speed: 5 parts by volume of pummelo peel essential oil (the content of D-limonene is not less than 96 percent), 2 parts by volume of sweet orange essential oil, 10 parts by volume of water, 23 parts by volume of propylene glycol, 50 parts by volume of vegetable glycerol and 8mg/mL of theanine. Compared with the test examples 1 to 3, the mint essential oil was not contained.
Test examples 2 to 4
The comparative example provides an electronic cigarette liquid, which is prepared by uniformly stirring the following components at a high speed: 5 parts by volume of pummelo peel essential oil (the content of D-limonene is not less than 96%), 2 parts by volume of sweet orange essential oil, 10 parts by volume of mint essential oil, 10 parts by volume of water, 23 parts by volume of propylene glycol and 50 parts by volume of vegetable glycerin. As compared with test examples 1 to 3, theanine was not contained.
Test example 3-1
The test example provides an electronic cigarette liquid which is prepared by uniformly stirring the following components at a high speed: 1 volume part of perilla essential oil, 1 volume part of sweet orange essential oil, 5 volume parts of mint essential oil, 5 volume parts of water, 38 volume parts of propylene glycol, 50 volume parts of vegetable glycerol and 5mg/mL of theanine.
Test examples 3 and 2
The test example provides an electronic cigarette liquid, which is prepared by uniformly stirring the following components at a high speed: 1 volume part of lavender essential oil, 1 volume part of sweet orange essential oil, 5 volume parts of mint essential oil, 5 volume parts of water, 38 volume parts of propylene glycol, 50 volume parts of vegetable glycerin and 5mg/mL of theanine.
Test examples 3 to 3
The test example provides an electronic cigarette liquid, which is prepared by uniformly stirring the following components at a high speed: 1 volume part of licorice essential oil, 1 volume part of sweet orange essential oil, 5 volume parts of mint essential oil, 5 volume parts of water, 38 volume parts of propylene glycol, 50 volume parts of vegetable glycerol and 5mg/mL of theanine.
Cough-inducing test
100 Kunming mice which are qualified in the primary screening are taken and randomly divided into 10 groups, each group comprises 10 mice, and the groups are divided into different treatment groups (electronic cigarette tobacco juice treatment groups of experimental examples 1-1 to 3, experimental examples 2-1 to 4 and experimental examples 3-1 to 4) and a single cough-inducing group. Continuously atomizing and administrating for three days, once respectively in the morning and afternoon. Fasting before administration in the morning on day 3 for 12h, carrying out ammonia water induced cough according to a preliminary screen after 1h of atomization administration, observing and recording cough times within 2min, and calculating cough inhibition rate. The statistical results are shown in the following table:
from the results, it can be seen that the electronic cigarette liquid of experimental examples 1-3 can significantly prolong the ammonia water-induced cough latency and reduce the number of coughs in mice. In other words, by the compatibility of the selected essential oil types, only a specific amount of exocarpium Citri Grandis essential oil can be used in combination with sweet orange essential oil, herba Menthae essential oil, etc. to achieve a good antitussive effect, and simultaneously, the exocarpium Citri Grandis essential oil can be used in combination with theanine.
140 volunteers with smoking habits are respectively selected for carrying out sensory evaluation on the using effect of the electronic cigarette liquid, 20 volunteers in each group are divided into 7 groups (which correspond to test examples 1-1 to 4 and test examples 3-1 to 4 respectively), and the statistical results are shown in the following table:
as can be seen from the above table, the electronic cigarette plumes of experimental examples 1 to 3 exhibited significant effects of relieving cough and reducing sputum, and also had soft and soft mouthfeel, natural flavor, and strong smoking comfort and pleasure.
It should be noted that the above examples are only for further illustration and description of the technical solution of the present invention, and are not intended to further limit the technical solution of the present invention, and the method of the present invention is only a preferred embodiment, and is not intended to limit the protection scope of the present invention. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (9)
1. An electronic cigarette liquid with a cough relieving effect is characterized by being mainly prepared from the following components: pummelo peel essential oil, sweet orange essential oil, mint essential oil, theanine, water, propylene glycol and vegetable glycerin;
wherein the volume ratio of the pummelo peel essential oil, the sweet orange essential oil, the mint essential oil, the water, the propylene glycol and the vegetable glycerin is (1-10): 1-5): 1-15): 5-12): 2-40): 40-60.
2. The electronic cigarette liquid with cough relieving effect as claimed in claim 1, wherein the volume ratio of the pummelo peel essential oil, the sweet orange essential oil, the mint essential oil, the water, the propylene glycol and the vegetable glycerin is (4-6): 1-3): 6-10): 5-12): 20-40): 40-60.
3. The electronic cigarette liquid with the cough relieving effect according to claim 2, wherein the volume ratio of the pummelo peel essential oil, the sweet orange essential oil, the mint essential oil, the water, the propylene glycol and the vegetable glycerin is 5:2:10:10 (20-25) to (40-60).
4. The electronic cigarette liquid with the cough relieving effect according to any one of claims 1 to 3, wherein the concentration of theanine is 5-10 mg/mL.
5. The electronic cigarette liquid with the cough relieving effect according to claim 4, wherein the concentration of theanine is 8 mg/mL.
6. The electronic cigarette liquid with the cough relieving effect according to any one of claims 1 to 3, wherein the pummelo peel essential oil is pummelo peel pure essential oil, and the D-limonene content of the pummelo peel pure essential oil is not lower than 96%.
7. The electronic cigarette liquid with the cough relieving effect according to any one of claims 1 to 3, wherein the theanine is theanine extracted from natural tea leaves;
the mint essential oil is natural mint essential oil;
the sweet orange essential oil is pure sweet orange essential oil.
8. The method for preparing the electronic cigarette liquid with the cough relieving effect of any one of claims 1 to 7, which is characterized by comprising the following steps: mixing exocarpium Citri Grandis essential oil, fructus Citri sinensis essential oil, herba Menthae essential oil, theanine, water, propylene glycol and vegetable glycerol, and stirring.
9. An electronic cigarette comprising the electronic cigarette liquid of any one of claims 1 to 7.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202210056764.7A CN114431509A (en) | 2022-01-18 | 2022-01-18 | Electronic cigarette liquid with cough relieving effect |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202210056764.7A CN114431509A (en) | 2022-01-18 | 2022-01-18 | Electronic cigarette liquid with cough relieving effect |
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| CN114431509A true CN114431509A (en) | 2022-05-06 |
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| CN202210056764.7A Pending CN114431509A (en) | 2022-01-18 | 2022-01-18 | Electronic cigarette liquid with cough relieving effect |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN115005487A (en) * | 2022-06-22 | 2022-09-06 | 深圳海克尔时代科技有限公司 | Electronic cigarette atomized liquid assisting in smoking control and quitting and preparation method thereof |
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| CN115005487A (en) * | 2022-06-22 | 2022-09-06 | 深圳海克尔时代科技有限公司 | Electronic cigarette atomized liquid assisting in smoking control and quitting and preparation method thereof |
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