CN114404527B - Traditional Chinese medicine composition for treating respiratory tract infection - Google Patents

Traditional Chinese medicine composition for treating respiratory tract infection Download PDF

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CN114404527B
CN114404527B CN202011170655.5A CN202011170655A CN114404527B CN 114404527 B CN114404527 B CN 114404527B CN 202011170655 A CN202011170655 A CN 202011170655A CN 114404527 B CN114404527 B CN 114404527B
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acute
respiratory tract
tract infection
shangganhe
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CN114404527A (en
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陶强
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JIANGXI CHILDREN' HOSPITAL
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A61K36/748—Oldenlandia or Hedyotis
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    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
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    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534—Mentha (mint)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/538—Schizonepeta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/74—Rubiaceae (Madder family)
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P11/02—Nasal agents, e.g. decongestants
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    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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Abstract

The invention discloses a traditional Chinese medicine composition for treating respiratory tract infection. The Chinese medicinal composition has effects of clearing heat and detoxicating, dispelling pathogenic wind and dispelling cold, and can not cause drug dependence of patients, especially dosage forms such as mixture and syrup, which are easy to be accepted by patients (especially children), and has good compliance of patients, and is helpful for improving curative effect.

Description

Traditional Chinese medicine composition for treating respiratory tract infection
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating respiratory tract infection (especially respiratory tract infection of children) and a preparation method thereof.
Background
Respiratory tract infections are one of the most common infectious diseases and can be classified into upper respiratory tract infections and lower respiratory tract infections. Upper respiratory tract infections refer to the general term for acute inflammation between the nasal cavity and the throat. Lower respiratory tract infections include bronchitis, pneumonia, bronchiectasis, and the like.
The cause of respiratory tract infections is thought to be caused by external and internal factors. The external factors include: 1. environmental pollution such as dust, haze and the like easily cause heavy moisture in external environment air, especially in spring, summer and autumn, the heavy moisture easily causes heat not to be easily dissipated, air humidity and stuffy is caused, people are easily invaded by humidity Wen Bingxie, and the people are easily suffered from wet temperature disease. The damp-warm disease evil in traditional Chinese medicine includes pathogenic bacteria of respiratory tract infection in Western medicine clinic, such as: bacteria, viruses, etc.; 2. the temperature difference of the environment is greatly changed, such as factors of cold, uneven cold and heat caused by improper use of an air conditioner, time and heat and the like; 3. adverse dietary structure effects, such as: people often eat cold and greasy food, often eat sweet and spicy food, often eat hot pot and wine, and easily turn heat in the body, so that modern constitutions are easy to form damp-heat constitutions due to environmental and dietary structure changes. Although the internal factors (such as deficiency of spleen and stomach) are normal in diet, there is a slight invasion of exogenous pathogenic factors, which tends to cause damp-heat to generate internally.
In the past, antibiotics are most commonly used for clinically treating respiratory tract infection. However, antibiotics also bring a lot of harm to human bodies while treating diseases: 1. the patients are affected by the environment and enter the body by pathogenic factors, and the drug resistance to antibiotics is easy to generate through the treatment of pure antibiotics, so that the medical cost of the patients is increased intangibly; 2. meanwhile, the use of antibiotics can increase the anaphylaxis rate, and the antibiotics which need to do skin test or do not need to do skin test can be used as a variant source, so that the human body can be allergic, the anaphylaxis rate of people with damp-heat constitution can be higher, various allergic skin diseases can be easily caused by slight anaphylactic hazard, and the death of the human body can be seriously caused; 3. the antibiotics are used for killing bacteria and simultaneously have great influence on normal cells of a human body, and the number of white blood cells of the human body is easily reduced and the immunity is easily reduced when the antibiotics are used frequently or for a long time; the patients are treated by the simple antibiotics, the environmental causes are not eliminated, the damp-heat physique is not changed, the immunity is reduced, the patients are easy to get ill again, the antibiotics are easy to form dependence on medicines, the drug resistance is increased, the allergic probability, the range and the degree are increased, the damp-heat allergic physique is easy to form, the prior non-allergic antibiotics can be allergic, the physique of the human body is further reduced, the treatment effect and the safety of the antibiotics are further reduced, and the vicious circle is formed.
The infant and children have low immune function, especially the children mostly like instant food at present, and various beverages are used for replacing water drinking, so that spleen and stomach dysfunction, gastrointestinal stagnation and morbidity are more common. However, some of the medicines on the market at present are not suitable for infants and children, and some of the medicines can be used for children, but the curative effect is not exact, or the dosage form and the taste of the product are not acceptable for children, so that the compliance of taking medicines for children is poor.
Disclosure of Invention
In order to overcome the defects in the prior art, the invention provides a composition which is prepared from the following traditional Chinese medicine raw materials in parts by weight: 50-150 parts of oldenlandia diffusa, 50-150 parts of gypsum, 50-100 parts of reed rhizome, 10-50 parts of schizonepeta, 30-60 parts of uncaria, and 10-50 parts of peppermint.
In one embodiment of the invention, the traditional Chinese medicinal materials consist of the following components in parts by weight: 50-150 parts of oldenlandia diffusa, 50-150 parts of gypsum, 50-100 parts of reed rhizome, 10-50 parts of schizonepeta, 30-60 parts of uncaria, and 10-50 parts of peppermint.
Specifically, the weight fraction of the oldenlandia diffusa in the traditional Chinese medicine raw materials can be 50, 60, 70, 80, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 120, 130, 140 and 150 parts.
Specifically, in the traditional Chinese medicine raw materials, the weight fraction of the gypsum can be 50, 60, 70, 80, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 120, 130, 140 and 150 parts.
Specifically, the weight fraction of the reed rhizome in the traditional Chinese medicine raw materials can be 50, 60, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 90 and 100 parts.
Specifically, in the traditional Chinese medicine raw materials, the weight fraction of the schizonepeta can be 10, 15, 20, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 40, 45 and 50 parts.
Specifically, the weight fraction of ramulus Uncariae cum Uncis in the above Chinese medicinal materials may be 30, 35, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 55, 60 parts.
Specifically, the weight fraction of the mint in the traditional Chinese medicine raw materials can be 10, 15, 20, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 40, 45 and 50 parts.
In one embodiment of the invention, the composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 100 parts of oldenlandia diffusa, 100 parts of gypsum, 75 parts of reed rhizome, 30 parts of schizonepeta, 45 parts of uncaria and 30 parts of mint.
In one embodiment of the invention, the traditional Chinese medicinal materials consist of the following components in parts by weight: 100 parts of oldenlandia diffusa, 100 parts of gypsum, 75 parts of reed rhizome, 30 parts of schizonepeta, 45 parts of uncaria and 30 parts of mint.
In one embodiment of the invention, the above composition is a pharmaceutical composition.
Specifically, the pharmaceutical composition further comprises pharmaceutically acceptable auxiliary materials.
Specifically, the pharmaceutically acceptable auxiliary materials may include a taste corrigent (specifically, sucrose, xylitol, fructo-oligosaccharide, sodium cyclamate, stevioside, aspartame, monosaccharide syrup, etc.), an aromatic agent (such as perfume, essence, etc.), a mucilage agent (specifically, sodium alginate, acacia, gelatin, methylcellulose, sodium carboxymethylcellulose, etc.), a clarifying agent (specifically, chitosan, gelatin, etc.), a preservative (specifically, benzoic acid and salts thereof (e.g., sodium benzoate), sorbic acid and salts thereof (e.g., potassium sorbate), a hydroxyphenyl ester (e.g., methylparaben, ethylparaben, butylparaben, etc.), a disintegrating agent (specifically, low-substituted hydroxypropylcellulose, croscarmellose sodium, starch, etc.), a binder (specifically, hydroxypropyl cellulose, hydroxypropyl methylcellulose, povidone, copovidone, pregelatinized starch, etc.), a lubricant (specifically, stearic acid, magnesium stearate, sodium fumaryl stearate, etc.), a wetting agent (specifically, sorbitol, polyoxyethylene sorbitan, castor oil, polyoxyethylene castor oil, etc.), a suspending agent (specifically, methylcellulose, a suspending agent, such as methylcellulose, a microcrystalline cellulose, a suspending agent, a microcrystalline cellulose, a suspending agent (specifically, a methylcellulose, a microcrystalline cellulose, a cellulose, etc.), cellulose derivatives, alginates, gelatin, polyvinylpyrrolidone, and the like), and the like.
Specifically, the above pharmaceutical composition may be in any dosage form or administration form, and those skilled in the art may choose according to circumstances, including, but not limited to, tablets, pills, powders, ointments, granules, lozenges, gums, capsules (including soft capsules, microcapsules), syrups, mixtures, wines, tinctures, lotions, injections (e.g., subcutaneous injections, intravenous injections, intramuscular injections, intraperitoneal injections), aerosols, films, suppositories, lotions, eye drops, ear drops, nose drops, and the like.
In one embodiment of the present invention, the pharmaceutical composition is a liquid medicament.
In one embodiment of the present invention, the pharmaceutical composition is a mixture.
Specifically, the solvent used in the preparation of the mixture is water.
In one embodiment of the present invention, the pharmaceutical composition is a syrup.
The various dosage forms of the above pharmaceutical composition may be prepared according to conventional production methods in the pharmaceutical field.
Specifically, the preparation method of the mixture comprises the following steps:
(1) Decocting Gypsum Fibrosum in water;
(2) Adding oldenlandia diffusa and reed rhizome into the decoction obtained in the step (1), decocting and filtering;
(3) Decocting herba Schizonepetae, ramulus Uncariae cum Uncis, and herba Menthae in water, and filtering;
(4) And (3) combining the filtrates obtained in the steps (2) and (3).
Specifically, the decoction in step (2) may be 1 or more times (e.g., 2, 3, 4, etc.).
Specifically, the step (2) may further include a step of concentrating the filtrate.
Specifically, the decoction in step (3) may be 1 or more times (e.g., 2, 3, 4 times, etc.).
Specifically, the step (3) may further include a step of concentrating the filtrate.
Specifically, the step (4) may further include a step of adding pharmaceutically acceptable auxiliary materials.
Specifically, the above preparation method may further comprise a step of sterilization.
Specifically, the preparation method can further comprise the step of sub-packaging.
Specifically, the preparation method of the syrup comprises the preparation method steps of the mixture, and the step (4) further comprises the step of adding syrup.
In one embodiment of the present invention, the syrup may be a simple syrup.
Specifically, the syrup also comprises a preservative.
In one embodiment of the present invention, the preservative is ethyl hydroxy benzoate.
In one embodiment of the present invention, the composition is a functional food composition.
Specifically, the functional food composition further comprises food auxiliary materials.
Specifically, the food auxiliary materials can comprise one or more of excipient, filler, forming agent, sweetener, colorant, coating agent, acidity regulator and the like.
Specifically, the above-mentioned functional food composition may take any form, such as tablets, pills, capsules (e.g., soft capsules, microcapsules), candies (e.g., tableted candies, gel candies, gum base candies, etc.), solid beverages (e.g., powders, granules, etc.), liquid beverages, etc.
The various forms of the above-described functional food composition may be prepared according to conventional production methods in the functional food field.
The invention also provides application of the composition in preparing medicines for preventing and/or treating respiratory tract infection.
The invention also provides application of the composition in preparing functional food for preventing respiratory tract infection or assisting in treating respiratory tract infection.
Specifically, the above-mentioned respiratory tract infections include upper respiratory tract infections and lower respiratory tract infections, and specifically include, but are not limited to, cold, rhinitis, pharyngitis, laryngitis, tonsillitis, tracheitis, bronchitis and pneumonia.
Specifically, the respiratory tract infections include acute respiratory tract infections and chronic respiratory tract infections.
In one embodiment of the present invention, the respiratory tract infection is an upper respiratory tract infection.
In one embodiment of the present invention, the respiratory tract infection is an acute respiratory tract infection.
In particular, the patient suffering from respiratory tract infections is a human, in particular a child, such as a child aged 1-14, 1-10, in particular 1-5.
The present invention also provides a method of preventing and/or treating a respiratory tract infection or aiding in the prevention and/or treatment described above, comprising the step of administering to a subject a composition of the invention described above.
Specifically, the above-mentioned respiratory tract infections include upper respiratory tract infections and lower respiratory tract infections, and specifically include, but are not limited to, cold, rhinitis, pharyngitis, laryngitis, tonsillitis, tracheitis, bronchitis and pneumonia.
Specifically, the respiratory tract infections include acute respiratory tract infections and chronic respiratory tract infections.
In one embodiment of the present invention, the respiratory tract infection is an upper respiratory tract infection.
In one embodiment of the present invention, the respiratory tract infection is an acute respiratory tract infection.
In particular, the subject is a human, particularly a child, such as a child aged 1-14 years, 1-10 years, particularly 1-5 years.
Aiming at respiratory tract infection, especially children respiratory tract infection, the invention provides a traditional Chinese medicine composition which can clear away heat and toxic materials, dispel wind and remove cold, does not cause the patient to generate drug dependence, especially the dosage forms of mixture, syrup and the like, is easy to be accepted by the patient (especially children), has better medication compliance of the patient and is beneficial to improving the curative effect.
Detailed Description
Unless defined otherwise, all scientific and technical terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention relates.
The "respiratory tract infection" refers to a disease caused by invasion of pathogenic microorganisms (including bacteria, viruses, mycoplasma, fungi, parasites, etc.) into the respiratory tract and propagation, and can be classified into upper respiratory tract infection and lower respiratory tract infection according to the site of occurrence thereof, the former including common cold, rhinitis, pharyngitis, laryngitis, tonsillitis, etc., and the latter including tracheitis, bronchitis, pneumonia, etc. Respiratory tract infections in the present invention include acute respiratory tract infections (e.g. acute pharyngitis, acute rhinitis, acute bronchitis) and chronic respiratory tract infections (e.g. recurrent symptoms last for more than one month, e.g. chronic tonsillitis, chronic rhinitis), in particular acute upper respiratory tract infections.
"child" means a human from the beginning of life birth to the beginning of adulthood, and in the present invention, the age of childhood is 0-18 years, especially 0-14 years, 1-10 years, and 1-5 years.
In the invention, the functional food refers to food with specific nutrition and health care functions, namely food which is suitable for specific people to eat, has the function of adjusting organism and does not aim at treatment. Functional foods are sometimes also referred to as health food products.
The term "effective amount" refers to the amount that achieves treatment, prevention, alleviation and/or relief of a disease or condition of the present invention in a subject, which depends on a number of factors, including the age, weight, sex, natural health condition, nutritional condition, time of administration, metabolic rate, severity of the condition, and subjective judgment of the physician, etc., and therefore the invention is not particularly limited.
The terms "patient", "subject" are used interchangeably herein and refer to an animal, such as a mammal, particularly such as a human, and in particular a child, that receives the compositions and methods of the present invention to treat, prevent, ameliorate and/or alleviate a disease or disorder described herein.
The term "treating" includes eradicating, removing, reversing, alleviating, altering or controlling the disease or disorder after its onset.
The term "preventing" refers to the ability to prevent, minimize or make difficult the onset or progression of a disease or disorder by treatment prior to the onset of the disease or disorder.
The traditional Chinese medicines of the raw materials in the composition of the invention are well described in Chinese pharmacopoeia, chinese dictionary and Chinese herbal medicine, for example:
Herba Hedyotidis Diffusae is whole plant of herba Hedyotidis Diffusae Hedyotis diffusa Willd of Rubiaceae [ Oldenlandia diffusa (Willd.) ] Roxb; slightly bitter in taste and cold in nature; stomach, large intestine and small intestine channels; efficacy: clearing heat and detoxicating, removing dampness and treating stranguria; the processing method comprises the following steps: removing impurities and soil, and sun drying.
Gypsum Fibrosum, which is sulfate mineral anhydrite, contains mainly hydrous calcium sulfate (CaSO 4 ·2H 2 O), sweet and pungent in flavor, and cold in nature; enter lung and stomach meridians; efficacy: clearing heat and purging fire, relieving restlessness and quenching thirst; the processing method comprises the following steps: cleaning, drying, pulverizing, removing impurity stone, and pulverizing into coarse powder.
Rhizoma Phragmitis is fresh or dried rhizome of reed Phragmites communis Trin of Gramineae; sweet in taste and cold in nature; enter lung and stomach meridians; efficacy: clearing heat and promoting fluid production, relieving restlessness, stopping vomiting and promoting urination; the processing method comprises the following steps: removing impurities, cleaning, cutting or sun drying.
Herba Schizonepetae is dry aerial part of herba Schizonepetae Schizonepeta tenuifolia Briq. Of Labiatae; pungent taste and slightly warm nature; enter lung and liver meridians; efficacy: relieving exterior syndrome, dispelling pathogenic wind, promoting eruption; the processing method comprises the following steps: removing impurities, spraying clear water, cleaning, moistening, cutting, and sun drying.
Ramulus Uncariae cum Uncis is dry hooked stem branch of Uncaria rhynchophylla 0 phyla (Miq.) of Rubiaceae, jacks, uncaria macrophylla Uncaria macrophylla wall, uncaria tomentosa Havill, uncaria sinensis (Oliv.) Havil. Or Uncaria sessilifolia Uncaria sessilifructus Roxb; sweet in taste and cool in nature; meridian entered liver and pericardium; efficacy: clearing heat and calming liver, and stopping wind and convulsion; the processing method comprises the following steps: removing old stems and impurities, cleaning and sun drying.
Peppermint is the dry aerial part of peppermint Mentha haplocalyx Briq of the genus Mentha of the family Labiatae; pungent taste and cool nature; enter lung and liver meridians; efficacy: disperse wind-heat, clear head and eyes, promote eruption; the processing method comprises the following steps: removing old stems and impurities, slightly spraying clear water, slightly wetting, cutting into short sections, and timely drying at low temperature.
The technical solutions of the present invention will be clearly and completely described in conjunction with the embodiments of the present invention, and it is apparent that the described embodiments are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Example 1: preparation of oral liquid
Formulation composition (i.e., the upper sense agent applied in example 3):
100g of oldenlandia diffusa, 100g of gypsum, 75g of reed rhizome, 30g of schizonepeta, 45g of uncaria and 30g of peppermint.
The preparation method comprises the following steps: decocting Gypsum Fibrosum in water for 30 min, adding herba Hedyotidis Diffusae and rhizoma Phragmitis into the decoction, decocting for 1 hr twice, filtering, mixing filtrates, concentrating to 300ml, decocting herba Schizonepetae, ramulus Uncariae cum Uncis and herba Menthae in water for 30 min twice, filtering, concentrating filtrate to 400ml, mixing with the above filtrate, adding 200ml of simple syrup and appropriate amount of ethyl hydroxybenzoate, adding water to 1000ml, mixing, packaging, sterilizing, and sealing.
The obtained product is brown liquid and sweet.
Example 2: analysis and identification of oral liquid
60ml of the liquid prepared in example 1 was taken and placed in a separating funnel, extracted twice with diethyl ether (20 ml,40 ml), the water layer was evaporated to dryness in water bath, and the residue was dissolved in 20ml of methanol and sonicated for 30 minutes, filtered, and the filtrate was concentrated to about 1ml as a test solution.
And adding methanol into oleanolic acid reference substance to obtain a solution containing 1mg per 1ml, and taking the solution as reference substance solution.
Thin layer chromatography (appendix VI B of 2005 edition of Chinese pharmacopoeia) test, the two solutions are respectively spotted on the same silica gel G plate, developed by using chloroform-acetone (95:5) as developing agent, taken out, dried in the air, sprayed with 5% sulfuric acid ethanol solution, and heated at 105 ℃ until the spots develop clearly. Spots with the same color are displayed on the corresponding positions of the chromatogram of the reference sample.
Example 3: clinical diagnosis and treatment of cases
The hospital in the children hospital in Jiangxi province, 2013, is plucked to diagnose and treat the children treatment cases as follows:
ID number/date of visit/prescription number/drug name/specification/quantity/diagnostic result
11140955/apply somewhere/2013/1/1:15:32:25/47712/upper sense agent/100 ml/1.00/bronchitis
11130039/Li certain/2013/1/5:16:34:03/89783/Shangganji/100 ml/1.00/acute pharyngitis
11143397/Zhang Mou 2013/1/5:17:14:27/90078/upper sense agent/100 ml/1.00/diaper rash (buttock erythema), bronchitis
11144704/Li certain/2013/1/7:19:56/11343/Shangganji/100 ml/1.00/acute pharyngitis
11145167/from 1/2013/1/8:10:44:28/19553/Shangganhe/100 ml/1.00/pharyngitis
11140676/Huqisome/2013/1/8:11:41:54/21125/Shangganhe/100 ml/1.00/bronchitis
10247975/grandchild/2013/1/9:25:52/34478/upper-feeling agent/100 ml/2.00/acute pharyngitis
11099261/Huqicertain/2013/1/9:11:43:31/34877/upper-respiratory-tract infection/100 ml/1.00/upper-respiratory-tract infection
11146194/Zhen somewhere/2013/1/9:25:58/37972/upper sensing agent/100 ml/1.00/upper respiratory tract infection
11146182/Huqicertain/2013/1/9:41:44/39527/Shangganji/100 ml/1.00/edema, acute pharyngitis
11113817/Huangxiao certain/2013/1/10:11:07:10/47583/upper airway infection/100 ml/4.00/upper airway infection
11073264/week 1/2013/1/10:11:19/47289/upper induction agent/100 ml/1.00/acute bronchiolitis
11042301/Lixisomebody/2013/1/10:51:04/48823/upper airway infection/100 ml/1.00/upper airway infection
11147282/Liu somewhere/2013/1/11:35:07/57404/Shangganhe/100 ml/1.00/bronchopneumonia
11147510/Qin certain/2013/1/11:51:32/60075/upper sensing agent/100 ml/1.00/upper respiratory tract infection
10528097/wang certain/2013/1/11:39:30/65064/upper induction agent/100 ml/3.00/respiratory tract infection
11124274/Xu Mou/2013/1/11:53:27/65363/upper airway infection/100 ml/1.00/upper airway infection
11148967/chapter somewhere/2013/1/13:29:56/86635/upper-respiratory-tract infection/100 ml/1.00/upper-respiratory-tract infection
11149145/Wuqi certain/2013/1/13:15:28/89291/Shangganhe/100 ml/1.00/acute pharyngitis
10431634/Huqicertain/2013/1/13:16:12/89273/Shangzhen/100 ml/2.00/granulocyte elevation, mumps
10888628/Liu somewhere/2013/1/15:14:59:41/19093/upper sense agent/100 ml/1.00/upper respiratory tract infection
11134704/Huqicertain/2013/1/16:11:58:42/31682/upper-sensing agent/100 ml/1.00/upper respiratory tract infection
11117367/Shenqi/2013/1/16:19:54/31988/upper airway infection/100 ml/1.00/upper airway infection
11151814/Aicertain/2013/1/16:28:13/35967/Shangganhe/100 ml/1.00/upper respiratory tract infection, rickets
11152264/Pengsomewhere/2013/1/17:13:38/45288/upper sense agent/100 ml/1.00/infectious fever
11152366/Lixisomebody/2013/1/17:16:19/46648/Shanggang mixture/100 ml/1.00/infant bronchitis
11037957/Jishi/2013/1/17:11:04/47679/Shangganji/100 ml/4.00/acute pharyngitis
11137410/Populus tomentosa/2013/1/17:11:54/47692/Shangganji/100 ml/4.00/acute pharyngitis
11008539/wang certain/2013/1/17:09:28/51202/Shangganji/100 ml/2.00/acute pharyngitis, upper respiratory infection
11097605/ certain/2013/1/18:17:10/56258/upper sense agent/100 ml/1.00/infant bronchitis
11152906/Song somewhere/2013/1/18:55:40/57632/upper respiratory tract infection/100 ml/1.00/upper respiratory tract infection, rickets
11153040/Hu Mou/2013/1/18:17:50/58325/Shangganhe/100 ml/1.00/acute pharyngitis
11153086/wang certain/2013/1/18:02:14/59631/Shangganhe/100 ml/1.00/bronchitis
11152649/Weathert/2013/1/18:15:56:28/62761/Shangganning mixture/100 ml/1.00/acute pharyngitis
11098309/Lixisomebody/2013/1/19:11:42:19/72162/Shangganhe/100 ml/3.00/acute bronchitis
11078027/xie somewhere/2013/1/19:49:13/73824/upper airway infection/100 ml/1.00/upper airway infection
10877705/Huqisome/2013/1/20:09:32/85877/Shangganhe/100 ml/1.00/bronchitis
10625134/Lixisomebody/2013/1/21:11:59:07/2582/upper-sensing agent/100 ml/1.00/upper respiratory tract infection
11114888/Chen somewhere/2013/1/22:08:11/12529/Shangganhe/100 ml/1.00/conjunctivitis
11156488/Huqicertain/2013/1/22:53:12/16836/upper airway infection/100 ml/2.00/acute upper airway infection
11156523/Wu certain/2013/1/22:11:32:37/17954/Shangganhe/100 ml/1.00/conjunctivitis
11157072/Qin certain/2013/1/23:30:56/28575/Shangganhe/100 ml/1.00/acute pharyngitis
11157470/Tang somewhere/2013/1/23:30:26/35228/upper sensing agent/100 ml/3.00/upper respiratory tract infection
11060626/permitted somebody/2013/1/23:00:26/38795/upper respiratory tract infection/100 ml/1.00/upper respiratory tract infection, rickets
11152045/bear some/2013/1/24:15:41:32/52285/upper induction agent/100 ml/1.00/acute pharyngolaryngitis, congenital heart disease
11139053/wang certain/2013/1/25:11:05:47/63145/Shangganji/100 ml/1.00/acute pharyngitis
11156488/Huqicertain/2013/1/25:53:50/64626/Shangganhe/100 ml/1.00/acute bronchitis
11032420/Huqicertain/2013/1/25:16:03:41/69500/upper-sensing agent/100 ml/1.00/upper respiratory tract infection
11085125/rusome/2013/1/26:17:33/83994/upper induction agent/100 ml/1.00/upper respiratory tract infection
10054633/Hesome/2013/1/27:10:02:56/90815/Shangganji/100 ml/3.00/acute pharyngitis
10986702/Dungcertain/2013/1/27:06:34/96994/upper airway infection/100 ml/1.00/upper airway infection
11161021/Li certain/2013/1/27:49:49/97907/Shangganhe/100 ml/1.00/jaundice, acute pharyngitis
11160872/what something/2013/1/27:16:24:46/98571/upper sense agent/100 ml/1.00/bronchitis
11140827/rotigong/2013/1/28:41:58/10684/upper sense agent/100 ml/1.00/acute bronchiolitis
11161816/Liu somewhere/2013/1/28:55:04/12590/Shangganhe/100 ml/1.00/acute pharyngitis
10371826/Liu Mou/2013/1/28:14:25:53/13250/Shangganhe/100 ml/2.00/acute pharyngitis
10839006/Liu somewhere/2013/1/28:14:38:27/13911/upper sense agent/100 ml/2.00/upper respiratory tract infection
11161780/Deng Mou/2013/1/28:43:20/14027/upper sense agent/100 ml/2.00/hydrocele of tunica vaginalis, scrotum infection
11163135/week-somewhere/2013/1/29:15:07/34575/upper-handicap/100 ml/1.00/infant bronchitis, bronchopneumonia
10982066/bear some/2013/1/30:11:48/42573/upper sense agent/100 ml/1.00/infectious fever
11163947/Liu somewhere/2013/1/30:50:12/46941/Shangganhe/100 ml/1.00/rash, upper respiratory tract infection
11161013/week 1/2013/1/31:11:05:22/65697/upper induction agent/100 ml/1.00/bronchopneumonia
11045183/Wu Mou/2013/2/2:11:20:16/113/upper airway infection agent/100 ml/2.00/bronchitis
10721180/Huqicertain/2013/2/2:15:23:12/3489/upper-sensing agent/100 ml/2.00/acute upper respiratory tract infection
11068879/Shuaisome/2013/2/2:15:30:22/3646/Shangganji/100 ml/1.00/Upper respiratory disease, dyspepsia, rickets
11168025/peri/2013/2/2 16:57:16/5253/upper induction agent/100 ml/5.00/acute pharyngitis
11168087/Qian somewhere/2013/2/2:20:28/6514/Shangganhe/100 ml/1.00/chronic rhinitis
10821586/Zhang Mou/2013/2/3:33:58/9793/Shangganhe/100 ml/1.00/acute tonsillitis
11081641/bear some/2013/2/3:15:57:49/18970/upper induction agent/100 ml/6.00/acute bronchitis, bronchopneumonia
11169443/Dusome/2013/2/4:27:43/28757/Shangganhe/100 ml/2.00/acute bronchitis
11170600/pay for 2013/2/5:54:28/46554/upper airway infection/100 ml/1.00/viral upper airway infection
11171091/wang certain/2013/2/5:08:43/53929/Shangganji/100 ml/2.00/acute pharyngitis
11062738/grandchild/2013/2/6:11:40/56970/upper-respiratory-tract infection/100 ml/5.00/acute upper-respiratory tract infection
11171413/Du certain/2013/2/6:30:41/59156/upper sensing agent/100 ml/1.00/viral upper respiratory tract infection
00425998/rotigong/2013/2/6 10:33:01/61488/upper sensing agent/100 ml/3.00/acute upper respiratory tract infection
11171570/Li certain/2013/2/6:11:16:21/63200/Shangganhe/100 ml/1.00/acute pharyngitis
11049555/Huangxiao certain/2013/2/6:11:16:24/63026/Shangganji/100 ml/1.00/acute pharyngitis
11148080/Zhang somewhere/2013/2/7:08:20/72669/upper-sensing agent/100 ml/1.00/acute upper respiratory tract infection
11172236/Condition somewhere/2013/2/7:38:56/73622/Shangganhe/100 ml/1.00/acute bronchitis
11164763/Bicertain/2013/2/7:09:00/74582/Shangganhe/100 ml/1.00/acute bronchiolitis
11172391/Jiang somewhere/2013/2/7:55:44/76018/upper airway infection/100 ml/1.00/acute upper airway infection
11165778/Lixisomebody/2013/2/7:14:00/77716/Shangganhe/100 ml/2.00
11156523/Wu certain/2013/2/7:52:28/80756/Shangganhe/100 ml/2.00/acute upper respiratory tract infection
10125380/Chen Jicertain/2013/2/7:12:02/81018/Shangganhe/100 ml/4.00/acute pharyngitis
11173101/Huqicertain/2013/2/8:11:04:56/88042/Shangganhe/100 ml/1.00/acute upper respiratory tract infection
11173932/bear some/2013/2/10:42:28/2744/upper sense mixture/100 ml/1.00/acute pharyngitis
11176272/what should be/2013/2/14:13:24/40811/upper induction agent/100 ml/1.00/acute pharyngitis
11178829/Zhen certain/2013/2/17:46:22/79243/Shang Gang Ji/100 ml/1.00/acute upper respiratory tract infection
11179839/innocent somewhere/2013/2/18:55:15/93865/upper induction agent/100 ml/1.00/acute bronchitis
10741471/Lixisome/2013/2/18:16:36:57/699/Shangganji/100 ml/1.00/acute pharyngitis
11182225/Rainbow/2013/2/20:15:32:16/27772/upper-sensing agent/100 ml/1.00/acute upper respiratory tract infection
11185088/horse certain/2013/2/23:04:47/72942/upper induction agent/100 ml/2.00/bronchopneumonia
10488568/Xusome/2013/2/24:49:47/79293/Shangganhe/100 ml/1.00/acute tonsillitis
11188608/Zhen certain/2013/2/27:11:46:51/27397/upper-sensing agent/100 ml/1.00/acute upper respiratory tract infection
11122410/xie somewhere/2013/2/28:9:36:22/38282/upper-sensing agent/100 ml/1.00/acute upper respiratory tract infection
10534211/Hesome/2013/2/28:38:15/45945/Shangganhe/100 ml/4.00/acute tonsillitis
11189749/Tian Mou/2013/2/28:16:31:42/47111/upper respiratory tract infection/100 ml/1.00/acute upper respiratory tract infection, rickets
11182892/Tian Mou/2013/2/28:31:54/46969/upper respiratory tract infection/100 ml/1.00/acute upper respiratory tract infection, rickets
11144639/Yuan certain/2013/3/1:22:41/53677/Shangganhe/100 ml/4.00/acute pharyngitis
11190764/Li certain/2013/3/1:11:17/61802/upper sensing agent/100 ml/1.00/acute upper respiratory tract infection
10839781/Song somewhere/2013/3/4:09:53/92169/upper airway infection/100 ml/2.00/acute upper airway infection
10839006/Liu somebody/2013/3/4:06:11/94771/Shangganhe/100 ml/2.00/acute pharyngitis, rickets
11095958/Zhang somewhere/2013/3/4 10:49:29/98443/Shanggang mixture/100 ml/1.00/chronic dacryocystitis
11108836/from 1/2013/3/4:15:41:54/6099/upper-respiratory-tract infection/100 ml/4.00/acute upper respiratory tract infection
11191660/rotigong/2013/3/4:42:40/6103/upper sensing agent/100 ml/1.00/acute upper respiratory tract infection
11193571/Lixisomebody/2013/3/4:16:36:20/7282/upper induction agent/100 ml/1.00/indirect inguinal hernia, acute upper respiratory infection
11148605/ certain/2013/3/5:22:00/22431/upper airway infection/100 ml/1.00/acute upper airway infection
11156432/chen somewhere/2013/3/6:52:12/29180/Shangganhe/100 ml/3.00/acute pharyngitis
11195052/Huangxiao certain/2013/3/6:40:59/31231/Shangganji/100 ml/1.00/acute bronchitis
11145477/Zhang certain/2013/3/6:35:04/35092/upper sense agent/100 ml/1.00/dysplasia
11114888/Chen somewhere/2013/3/8:28:09/62745/Shangganhe/100 ml/1.00/conjunctivitis
11187335/chapter somewhere/2013/3/8:57:44/66444/upper-respiratory-tract infection/100 ml/1.00/acute upper-respiratory tract infection
00000260/Liu somewhere/2013/3/11:57:57/3452/Shangganhe/100 ml/10.00
11200784/Xiacertain/2013/3/11:11:11:02/23136/Shangganhe/100 ml/1.00/bronchitis
11197983/child certain/2013/3/11:36:21/26109/upper induction agent/100 ml/1.00/acute pharyngitis
11026556/Pengsomewhere/2013/3/11:34:45/27771/Shangganji/100 ml/1.00/acute pharyngitis
11195839/Jiang somewhere/2013/3/11:09:30/28446/Shangganji/100 ml/1.00/acute pharyngitis
10900391/should someone/2013/3/13:16:32:57/62765/upper-sensing agent/100 ml/1.00/acute upper respiratory tract infection
00000391/Chen Mou/2013/3/14:20:43/6534/upper-sense agent/100 ml/3.00
11073322/Moxiao certain/2013/3/15:10:39:54/86920/Shangganhe/100 ml/2.00/bronchitis
10917683/Mei Ji certain/2013/3/16:44:01/5518/Shangganhe/100 ml/1.00/bronchitis
10905237/Zhang somewhere/2013/3/16:17:02:02/9564/Shangganhe/100 ml/1.00/acute pharyngitis
11171819/Hu Mou/2013/3/17:23:06/18942/Shangganhe/100 ml/1.00/bronchitis
11170419/Gong's certain 2013/3/18:06:26/30934/Shangganhe/100 ml/1.00/bronchitis
11207209/Lixisomebody/2013/3/18:53:57/32537/Shanggang agent/100 ml/1.00/acute bronchiolitis
11168955/Pengsomewhere/2013/3/18:44:17/39354/Shangganji/100 ml/1.00/acute pharyngitis
11208761/wang certain/2013/3/19:15:35:55/55626/Shangganji/100 ml/1.00/acute pharyngitis
11209234/Taozhi/2013/3/20:43:00/66103/Shangganji/100 ml/1.00/acute pharyngitis
11209332/Lixisomebody/2013/3/20:11:21:14/67370/upper-sensing agent/100 ml/1.00/acute upper respiratory tract infection
11209995/what should be/2013/3/21 10:05:01/79390/upper sense agent/100 ml/1.00/prostatic nodule
11211025/ certain/2013/3/22:09:05/94872/Shangganhe/100 ml/1.00/bronchitis
11211555/Deng Mou/2013/3/22:16:46:41/3046/upper induction agent/100 ml/3.00/acute pharyngitis
11211772/clock/2013/3/23:14:53/6100/upper sense agent/100 ml/6.00/bronchitis
11211793/bear some/2013/3/23:34:02/8658/upper sense agent/100 ml/1.00/infectious fever
11053242/Lun somewhere/2013/3/23:52:31/16281/upper airway infection/100 ml/1.00/acute upper airway infection
11061007/Lin certain/2013/3/23:57:42/16437/Shangganhe/100 ml/1.00/Upper respiratory disease, rickets
11213556/bear some/2013/3/25:10:16:57/38816/upper induction agent/100 ml/1.00/acute upper respiratory tract infection, rickets
11182454/journey someone/2013/3/25:10:41:11/39572/upper induction agent/100 ml/1.00/acute upper respiratory tract infection
11026534/Chen somewhere/2013/3/25:10:59:56/40697/Shangganhe/100 ml/1.00/infectious fever, acute pharyngitis
11213848/bear some/2013/3/25:12:10:22/43043/upper sense agent/100 ml/1.00/bronchopneumonia
11089162/apply somewhere/2013/3/27:10:51:18/70913/upper sense agent/100 ml/1.00/infectious fever
11216018/rotigong/2013/3/27:16:59:41/78587/upper sense agent/100 ml/1.00/prostatic nodule
11217638/Zhou Mou/2013/3/29:25:17/1343/Shangganhe/100 ml/4.00/acute pharyngitis
11174658/fan somewhere/2013/4/1:10:40:36/47525/upper-respiratory-tract infection/100 ml/1.00/acute upper-respiratory tract infection
10839781/Song Mou/2013/4/1:44:03/54863/upper airway infection/100 ml/2.00/acute upper airway infection
10873171/operating someone/2013/4/2 10:37:05/64903/upper sense agent/100 ml/1.00/bronchitis
11221658/Chen-some/2013/4/2:11:47:38/67786/Shangganhe/100 ml/1.00/acute lower respiratory tract infection, bronchopneumonia
11222089/Wu certain/2013/4/2:18:10:24/73049/Shangganhe/100 ml/2.00/acute upper respiratory tract infection, acute pharyngitis
11222731/Chen Jicertain/2013/4/3:55:00/84605/Shangganhe/100 ml/1.00/acute pharyngitis
11215854/Wei certain/2013/4/3:57:23/86757/upper sense agent/100 ml/1.00/bronchopneumonia
11194506/somewhere/2013/4/5:10:51:46/94753/upper sense mixture/100 ml/1.00/nausea and vomiting, acute pharyngitis, auditory nerve injury
10965107/wanqi/2013/4/5:11:32:15/10479/Shangganji/100 ml/1.00/acute pharyngitis
11180343/Liu somebody/2013/4/5:55:17/15174/Shangganhe/100 ml/1.00/acute upper respiratory tract infection, rickets
11193075/Guo certain/2013/4/7:46:01/38006/upper induction agent/100 ml/1.00/acute upper respiratory tract infection
00822352/Sunzhixiao/2013/4/7:34:38/41968/Shangganji/100 ml/2.00/acute tonsillitis
11226305/Lixisomebody/2013/4/7:01:36/42349/Shangganhe/100 ml/1.00/bronchitis
10703336/Guqicertain/2013/4/7:50:37/48059/Shangganhe/100 ml/2.00/bronchitis
11227747/week 1/2013/4/8:15:46:44/62905/Shangganhe/100 ml/5.00/acute pharyngitis
11228762/Populus tomentosa/2013/4/9:02:37/79742/upper induction agent/100 ml/1.00/acute upper respiratory tract infection
11226121/what is/2013/4/10:11:02:25/90741/upper sensing agent/100 ml/1.00/ventricular septal defect
11213550/Tianxiao/2013/4/11:13:02/3183/Shangganhe/100 ml/1.00/acute tonsillitis
10034315/Tao Mou/2013/4/11:45:14/10815/upper induction agent/100 ml/1.00/congenital heart disease
11230877/Chua somebody/2013/4/11:30:46/13598/Shangganhe/100 ml/1.00/acute pharyngitis
11197122/Zhou certain/2013/4/12:53:38/18901/Shangganhe/100 ml/1.00/acute tonsillitis
11045183/Wu Mou/2013/4/16:10:48:39/92310/Shangganhe/100 ml/2.00/acute pharyngitis
11236702/Zhou certain/2013/4/17:46:51/13321/upper induction agent/100 ml/1.00/upper respiratory disease, rickets
11156806/Wu certain/2013/4/18:11:18/28488/Shangganhe/100 ml/1.00/congenital heart disease
11180709/Xuexisomecertain/2013/4/19:10:39:15/38862/upper induction agent/100 ml/1.00/viral upper respiratory tract infection
11153816/Zhang certain/2013/4/19:15:01:05/43632/Shangganji/100 ml/2.00/acute pharyngitis
10877705/Huqisome/2013/4/20:10:40:29/53227/Shangganhe/100 ml/2.00/acute tonsillitis
11239586/Shoucertain/2013/4/20:45:24/59110/Shangganji/100 ml/1.00/acute upper respiratory tract infection
11241628/wang certain/2013/4/22:21:12/91155/Shangganji/100 ml/2.00/enterovirus infection, acute pharyngitis
00427778/Lixisomebody/2013/4/23:13:23/4668/upper sense agent/100 ml/2.00/indirect inguinal hernia, acquired trunk deformity
11243303/bear some/2013/4/24:16:19:00/19349/upper induction agent/100 ml/1.00/upper respiratory disease, dyspepsia, rickets
11243879/Chen somewhere/2013/4/25:10:21:40/27127/Shangganhe/100 ml/1.00/acute upper respiratory tract infection
11243884/Dusome/2013/4/25:39:12/28321/upper-respiratory-tract infection/100 ml/1.00/acute upper-respiratory tract infection
11230134/Gong's certain/2013/4/25:14:52:41/32347/Shangganhe/100 ml/1.00/acute bronchitis
11244290/Gaobao/2013/4/25:16:12:27/34303/Upper sensing agent/100 ml/1.00/viral upper respiratory tract infection
11245111/Lixisome/2013/4/26:41:18/47219/Shangganji/100 ml/1.00/acute pharyngitis
11232894/Zhou certain/2013/4/27:11:16:19/60289/Shangganhe/100 ml/1.00/acute pharyngitis
10054633/some other/2013/4/30 11:17:29/12462/Shangganji/100 ml/3.00/acute pharyngitis, precocious puberty, bronchitis
11251564/bear some/2013/5/2 10:43:54/44503/Shangganhe/100 ml/2.00/acute pharyngitis
11251777/Hesome/2013/5/2:15:42/47513/Shangganhe/100 ml/5.00/acute pharyngitis
10644074/ginger somebody/2013/5/2:13:21:52/48926/upper induction agent/100 ml/3.00/acute suppurative otitis media
10416893/Liu somewhere/2013/5/3:39:46/57927/Shangganhe/100 ml/2.00/acute tonsillitis
11158194/Luo Mou/2013/5/8:11:02:05/54721/upper sense agent/100 ml/1.00/acute bronchiolitis
11227301/bear some/2013/5/9:53:18/76332/upper sense mixture/100 ml/1.00/acute pharyngitis
11260722/Huangxiao certain/2013/5/10:21:42/86585/Shangganhe/100 ml/1.00/acute upper respiratory tract infection
11260619/Zhen certain/2013/5/10:24:23/86476/upper sensing agent/100 ml/1.00/viral upper respiratory tract infection
11244424/rotigong/2013/5/10:11:17:44/88423/upper sensing agent/100 ml/1.00/acute upper respiratory tract infection
10793928/peri/2013/5/12:06:36/26904/upper induction agent/100 ml/2.00/acute pharyngitis
11263989/Yin certain/2013/5/13:25:22/38849/Shangganhe/100 ml/1.00/acute pharyngitis
11194811/Lixisomebody/2013/5/13:20:21/49314/Shangganji/100 ml/1.00/acute pharyngolaryngitis
11267713/Huqicertain/2013/5/16:02:24/96744/upper-sensing agent/100 ml/1.00/acute upper respiratory tract infection
11267981/Xu Mou/2013/5/17:09:59/9279/upper airway infection/100 ml/1.00/acute upper airway infection
11270235/che certain/2013/5/19:11:22/42854/Shangganhe/100 ml/1.00/acute upper respiratory tract infection, rickets
11270670/scribble some/2013/5/19:48:58/46878/upper induction agent/100 ml/2.00/acute upper respiratory tract infection, heart murmur
11271303/Xusome/2013/5/20:48:05/55541/Shangganhe/100 ml/1.00/bronchitis
11115365/wang certain/2013/5/22:48:18/96463/Shangganji/100 ml/1.00/acute pharyngitis
11276097/Xie Mou/2013/5/24:27:01/27898/Shangganhe/100 ml/1.00/acute pharyngitis
00806163/Xuesome/2013/5/25:19:10:51/49296/upper-sensing agent/100 ml/3.00/acute upper respiratory tract infection
10452228/Lixisomebody/2013/5/26:11:19:09/58813/upper-sensing agent/100 ml/1.00/acute upper respiratory tract infection
11270467/Xiacertain/2013/5/27:17:08/72381/Shangganhe/100 ml/1.00/acute pharyngitis
11285747/Zhengsomewhere/2013/6/3:46:55/83224/Shangganhe/100 ml/1.00/acute pharyngitis, rickets
11108836/from 1/2013/6/3:10:44:37/90464/upper airway infection/100 ml/3.00/acute upper airway infection
11286887/somewhere left/2013/6/4:56:59/17272/upper airway infection agent/100 ml/1.00/sepsis
11289038/week-somewhere/2013/6/5:20:11/37204/Shangganji/100 ml/1.00/febrile, acute pharyngitis
11179793/Hesome/2013/6/7:24:20/70732/Shangganhe/100 ml/1.00/acute pharyngitis
10875779/Min somewhere/2013/6/8:16:45:12/84609/Shangganhe/100 ml/1.00/acute pharyngitis
11179793/Hesome/2013/6/8 22:23:08/86771/Shangganhe/100 ml/1.00/acute pharyngitis
11280032/Liu somewhere/2013/6/12:14:47:37/41853/Shangganhe/100 ml/1.00/acute pharyngitis
11295397/nie certain/2013/6/12:04:50/43251/Shangganhe/100 ml/1.00/acute pharyngitis
11295490/wang certain/2013/6/12:27:25/44636/upper airway infection agent/100 ml/1.00/sepsis
11190438/about some 2013/6/14:26:16/67484/upper sense agent/100 ml/1.00/sepsis
11297877/Chen Jicertain/2013/6/14:43:31/79219/Shangganhe/100 ml/1.00/acute pharyngitis
10965463/bear some/2013/6/14:16:10:35/80056/upper sense mixture/100 ml/1.00/acute pharyngitis
11044229/Lixisomebody/2013/6/14:20:36:01/82455/Shangganji/100 ml/4.00/acute pharyngitis, bronchitis
11299009/Maozi/2013/6/15:06:43/96548/Shangganhe/100 ml/3.00/acute upper respiratory tract infection, bronchitis
11301774/wang certain/2013/6/18:9:19:59/39786/upper-sensing agent/100 ml/1.00/acute upper respiratory tract infection
11294314/Xusome/2013/6/19:11:54:12/62796/Shangganji/100 ml/1.00/acute pharyngitis
11303471/von somewhere/2013/6/19:29:47/68585/upper-sense mixture/100 ml/3.00/acute upper respiratory tract infection, acute pharyngitis
10847110/Dong somewhere/2013/6/20:28:53/84555/upper-sensing agent/100 ml/6.00/acute upper respiratory tract infection
11297288/Li certain/2013/6/21:11:05:58/94353/Shangganji/100 ml/1.00/acute pharyngitis
11062738/Sunzhixiao/2013/6/22:56:31/14003/Shangganji/100 ml/4.00/acute tonsillitis
11103354/Min somewhere/2013/6/23:16:39:24/29765/Shangganhe/100 ml/1.00/acute pharyngitis
11303790/xie somewhere/2013/6/24:25:36/39548/Shangganhe/100 ml/1.00/acute bronchitis
11288915/Bian/2013/6/24:42:41/40833/Shangganhe/100 ml/1.00/acute pharyngitis
11156956/wang certain/2013/6/24:57:05/47185/Shangganji/100 ml/1.00/acute pharyngitis
11311195/Gong's certain/2013/6/27:47:11/90082/upper sense agent/100 ml/2.00/respiratory disease
11311199/Chua somebody/2013/6/27:52:41/90247/upper sense agent/100 ml/2.00/respiratory disease
11188108/what should be/2013/6/28:23:37/14891/upper induction agent/100 ml/1.00/acute pharyngitis
10879457/Zhongcertain/2013/6/28:17:20:55/20679/Shangganhe/100 ml/2.00/congenital heart disease
11313716/Feng Mou/2013/6/29:53:22/30915/upper airway infection/100 ml/2.00/acute upper airway infection, acute pharyngitis
11316449/Guiqi/2013/7/2 10:01:24/81691/upper induction agent/100 ml/1.00/septicemia, bronchitis
11320302/Xiacertain/2013/7/4:17:01/29192/Shangganhe/100 ml/1.00/acute upper respiratory tract infection
11320761/ certain/2013/7/4 18:03:49/35541/upper induction agent/100 ml/4.00/acute pharyngitis
11226048/Wang somewhere/2013/7/7:9:09:37/77208/Shangganhe/100 ml/1.00/acute pharyngitis
11323313/what should be/2013/7/7:9:20:15/77593/Shangganhe/100 ml/1.00/acute pharyngitis
11091667/Li certain/2013/7/7:12:02:06/83135/Shangganji/100 ml/1.00/acute pharyngitis
11077116/Jiang somewhere/2013/7/8:15:19:58/5385/Shangganji/100 ml/5.00/acute pharyngitis
11324146/Pan Mou/2013/7/8:20:10/5397/upper sense mixture/100 ml/1.00/acute tonsillitis
11329134/wang certain/2013/7/11:33:30/64476/upper airway infection/100 ml/1.00/acute upper airway infection
10946980/poplar somebody/2013/7/12:37:24/76615/upper induction agent/100 ml/2.00/acute upper respiratory tract infection, rickets
10839781/Song Mou/2013/7/15:19:04/17243/Shangganhe/100 ml/2.00/acute pharyngitis
11259912/Liu somewhere/2013/7/15:21:19/26490/Shangganhe/100 ml/1.00/acute pharyngitis
11335847/Zhucertain/2013/7/17:36:38/70237/Shangganhe/100 ml/1.00/acute pharyngitis
11337548/Hu Mou/2013/7/19:23:48/2668/upper-sensing agent/100 ml/2.00/acute upper respiratory tract infection
11338120/Gu Mou/2013/7/19:16:49:43/7314/upper induction agent/100 ml/1.00/acute pharyngitis
11338170/Dungcertain/2013/7/19:56:48/7916/Shangganhe/100 ml/1.00/acute pharyngitis
11227828/week 1/2013/7/22:11:18:06/49306/Shangganhe/100 ml/1.00/acute pharyngitis
11341764/Zhang Mou/2013/7/23:45:40/63758/upper airway infection/100 ml/1.00/acute upper airway infection
11317785/Jiang somewhere/2013/7/23:26:41/68004/Shanggang mixture/100 ml/2.00/acute upper respiratory tract infection
11343546/wang certain/2013/7/24:43:18/92598/Shangganji/100 ml/1.00/acute pharyngitis
11345224/Zhen certain/2013/7/26 11:51:57/21825/Shangganhe/100 ml/1.00/acute upper respiratory tract infection
11342577/Zhu somewhere/2013/7/30:11:14:37/84891/Shangganhe/100 ml/1.00/Special examination
11273824/week 1/2013/8/3:07:18/55922/upper induction agent/100 ml/1.00/acute pharyngitis
11251777/Hesome/2013/8/4:18:22/69980/Shangganhe/100 ml/2.00/acute pharyngitis
11346611/Yao certain/2013/8/5:17:39/75082/Shangganhe/100 ml/1.00/acute pharyngitis
11355272/Lixisomebody/2013/8/5:21:12/75570/Shangganji/100 ml/1.00/constipation
11135583/Chapter somewhere/2013/8/5:32:48/86038/Shangganji/100 ml/1.00/acute pharyngitis
11355974/Gong's girl/2013/8/5:09:42/86946/Shangganning mixture/100 ml/1.00/bronchitis
11357552/Weather/2013/8/7:30:29/13532/Shangganhe/100 ml/1.00/abdominal pain, dyspepsia
11207462/bear some/2013/8/7:08:31/15115/upper body feeling agent/100 ml/1.00/acute pharyngitis
11357878/fan somewhere/2013/8/7:21:51/15865/upper-sensing agent/100 ml/1.00/acute upper respiratory tract infection
11358247/somewhere/2013/8/7:37:21/24105/upper-respiratory-tract infection/100 ml/1.00/viral upper-respiratory-tract infection
11355376/Zhen certain/2013/8/8:11:38:04/35870/upper-sensing agent/100 ml/1.00/acute upper respiratory tract infection
11355622/Huang Mou/2013/8/12:01:19/90228/Shangganhe/100 ml/1.00/bronchitis
11362692/nie certain/2013/8/12:23:28/93756/Shangganhe/100 ml/1.00/acute bronchiolitis
11362982/Dungcertain/2013/8/12:00:06/98331/Shangganhe/100 ml/1.00/febrile, acute pharyngitis
11367358/Chen somewhere/2013/8/16:18:03:24/66352/Shangganhe/100 ml/3.00/acute upper respiratory tract infection
10848507/wang certain/2013/8/24:30:40/76170/Shangganhe/100 ml/4.00/bronchitis
11310923/Chen Jicertain/2013/8/28:09:52/46841/Shangganhe/100 ml/2.00/acute pharyngitis
10266731/Moxiao certain/2013/8/30:20:24:24/94019/Shangganhe/100 ml/1.00/acute tonsillitis
11387297/Liu somewhere/2013/9/6:12:15/86334/Shangganhe/100 ml/1.00/acute pharyngitis
11122755/Wu Mou/2013/9/6:18:59/90728/upper airway infection/100 ml/1.00/acute upper airway infection
11390701/Lisomebody/2013/9/12:27:43/76078/upper induction agent/100 ml/1.00/acute upper respiratory tract infection, congenital heart disease
11317665/Liu somewhere/2013/9/14:10:36:01/8981/upper sensing agent/100 ml/1.00/acute upper respiratory tract infection
11399217/about some/2013/9/19 10:39:15/91102/Shangganhe/100 ml/1.00/acute pharyngitis
11402972/Chen Jicertain/2013/9/22:21:54/47391/Shangganhe/100 ml/1.00/acute pharyngitis
10703336/Guqicertain/2013/9/26:48:46/5339/Shangganhe/100 ml/2.00/acute tonsillitis
11407746/Huqicertain/2013/9/27:22:14/27677/Shangganhu/100 ml/1.00/tibial fracture
11386901/Saint/2013/9/28:46:04/44822/Shangganhe/100 ml/2.00/acute nasopharyngitis
11409397/from somewhere/2013/9/29 10:32:00/54306/Shangganhe/100 ml/1.00/acute pharyngitis
11337843/Mei Ji certain/2013/9/30:10:44:11/70673/Shangganhe/100 ml/4.00/acute upper respiratory tract infection
11020149/lan certain/2013/10/1:27:47/85633/Shangganhe/100 ml/1.00/acute upper respiratory tract infection, rickets
10747329/Xusome/2013/10/1:42:20/91039/Shangganhe/100 ml/1.00/nutritional anemia, rickets
10054633/somewhere else/2013/10/2:15:04:23/6019/Shangganhe/100 ml/1.00/acute pharyngitis, central precocity
10431634/Huqisome/2013/10/4:22:18/45736/Shangganhe/100 ml/2.00/acute tonsillitis
10796044/Hesome/2013/10/8:14:51/4833/Shangganhe/100 ml/4.00/acute pharyngitis
11325855/somewhere/2013/10/11:16:17/61010/upper sense agent/100 ml/1.00/tracheobronchitis, precocious puberty
11426125/Zhengsomewhere/2013/10/15:39:15/26052/upper induction agent/100 ml/3.00/acute upper respiratory tract infection, dyspepsia
11390303/wang certain/2013/10/17:16:17:05/66381/Shangganji/100 ml/1.00/acute pharyngolaryngitis
11226271/Guo certain/2013/10/19:47:04/96425/Shangganhe/100 ml/1.00/acute pharyngitis
10986781/dropoff/2013/10/19:27:52/1569/Shangganji/100 ml/6.00/acute pharyngitis
11432015/Zhou certain/2013/10/21:34:29/34745/Shangganhe/100 ml/4.00/acute pharyngitis
08315141/included somewhere/2013/10/21:16:32:40/35953/upper-respiratory-agent/100 ml/2.00/acute upper respiratory tract infection, premature infant
08305972/leaf somewhere/2013/10/22:14:46:50/51881/upper-sensing agent/100 ml/1.00/acute upper respiratory tract infection
08310597/journey someone/2013/10/23:04:08/64399/upper induction agent/100 ml/1.00/acute upper respiratory tract infection
11320761/ certain/2013/10/24:11:46:45/86439/upper-sensing agent/100 ml/3.00/acute upper respiratory tract infection
08308745/Huqicertain/2013/10/27:16:41:59/46197/upper-sensing agent/100 ml/2.00/acute upper respiratory tract infection
11283135/Mei Ji certain/2013/10/27:16:20/47993/Shangganhe/100 ml/1.00/acute pharyngitis
08321573/Cao Mou/2013/10/30:32:45/99369/Shangganhe/100 ml/1.00/jaundice, acute pharyngitis
08329445/Lei certain/2013/10/30:14:05/5716/Shangganhe/100 ml/1.00/acute pharyngitis
11432671/Liu somewhere/2013/10/31:11:32:02/19464/Shangganhe/100 ml/1.00/acute pharyngitis
11295545/Wang Mou/2013/11/1:30:19/33432/upper respiratory tract infection/100 ml/1.00/acute upper respiratory tract infection, rickets
08308549/decoction of certain/2013/11/1:14:35/36314/upper-body mixture/100 ml/1.00/congenital heart disease, bronchopneumonia
10054633/some other/2013/11/3:14:31:34/71843/Shangganji/100 ml/3.00/acute pharyngitis, precocious puberty
08295619/Xuesome/2013/11/4:23:34/86481/upper sense agent/100 ml/1.00/neonatal skin infection
11426062/Dungcertain/2013/11/5:34:59/3375/Shangganhe/100 ml/1.00/acute pharyngitis
08322905/Xusome/2013/11/9:59:29/66120/Shangganhe/100 ml/1.00/upper respiratory disease, rickets
100005999/fujia/2013/11/12:03:20/9571/Shangganhe/100 ml/1.00/bronchitis
08284225/danger something/2013/11/13:42:15/23647/upper sense mixture/100 ml/1.00/acute pharyngitis
11397838/Wei certain/2013/11/15:28:47/48741/Shangganhe/100 ml/1.00/acute pharyngitis
11339780/Lixisomebody/2013/11/17:09:43/71121/upper-sensing agent/100 ml/1.00/acute upper respiratory tract infection
11047516/Zhongcertain/2013/11/19:16:14:32/1770/Shangganhe/100 ml/2.00/acute tonsillitis
11320761/ certain/2013/11/19:44:21/2311/upper-sensing agent/100 ml/4.00/acute upper respiratory tract infection
11348566/Lixisomebody/2013/11/20:51:50/12476/upper airway infection/100 ml/1.00/acute upper airway infection, vitamin D deficiency
100010269/Huqicertain/2013/11/21:27:08/19528/upper-sensing agent/100 ml/1.00/acute upper respiratory tract infection
11429017/xie somewhere/2013/11/21:15:36:52/27941/Shangganji/100 ml/1.00/acute pharyngolaryngitis, eczema
100042295/bear certain/2013/11/24:23:27/66864/upper induction agent/100 ml/1.00/acute upper respiratory tract infection
00000543/rotcertain/2013/11/25 14:58:39/5568/upper sense agent/100 ml/2.00
100014770/Lisome/2013/11/28 9:59:55/14057/Shangganji/100 ml/1.00/acute pharyngitis, neonatal fever, neonatal omphalia, infantile diarrhea
100040237/chapter somewhere/2013/11/30:35:03/44755/upper induction agent/100 ml/1.00/viral upper respiratory tract infection, rickets
10503132/Shifting somewhere/2013/12/2 16:05:25/72311/Shangganhe/100 ml/5.00/acute upper respiratory tract infection
100019686/some of the ways/2013/12/2 16:06:10/72319/Shangganhe/100 ml/3.00/acute pharyngitis
100007727/Pei Mou/2013/12/3:11:23:20/82235/Shangganhe/100 ml/1.00/bronchitis
11308434/Zhen certain/2013/12/9:56:20/68512/Shangganhe/100 ml/2.00/acute upper respiratory tract infection
The symptoms of the patients are improved and healed after the treatment.
The foregoing description of the preferred embodiments of the invention is not intended to be limiting, but rather is to be construed as including any modifications, equivalents, and alternatives falling within the spirit and principles of the invention.
The foregoing embodiments and methods described in this invention may vary based on the capabilities, experience, and preferences of those skilled in the art.
The listing of the steps of a method in a certain order in the present invention does not constitute any limitation on the order of the steps of the method.

Claims (8)

1. The composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 100 parts of oldenlandia diffusa, 100 parts of gypsum, 75 parts of reed rhizome, 30 parts of schizonepeta, 45 parts of uncaria and 30 parts of mint;
the composition is a mixture or syrup, and the preparation method comprises the following steps:
(1) Decocting Gypsum Fibrosum in water;
(2) Adding oldenlandia diffusa and reed rhizome into the decoction obtained in the step (1), decocting and filtering;
(3) Decocting herba Schizonepetae, ramulus Uncariae cum Uncis, and herba Menthae in water, and filtering;
(4) And (3) combining the filtrates obtained in the steps (2) and (3).
2. The composition of claim 1, wherein step (4) further comprises the step of adding a pharmaceutically acceptable excipient.
3. The composition of claim 2, wherein the adjuvant comprises syrup and/or a preservative.
4. Use of a composition according to any one of claims 1 to 3 for the preparation of a medicament for the prophylaxis and/or treatment of respiratory tract infections.
5. The use according to claim 4, wherein the respiratory tract infection is selected from the group consisting of: common cold, rhinitis, pharyngitis, laryngitis, tonsillitis, tracheitis, bronchitis and pneumonia.
6. The use according to claim 4, wherein the respiratory tract infection is an acute respiratory tract infection.
7. The use according to any one of claims 4-6, wherein the patient suffering from respiratory tract infection is a child.
8. The use according to any one of claims 4 to 6, wherein the patient suffering from respiratory tract infection is a child aged 1 to 5 years.
CN202011170655.5A 2020-10-28 2020-10-28 Traditional Chinese medicine composition for treating respiratory tract infection Active CN114404527B (en)

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Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
中医治疗小儿上感160例疗效分析;王传吉等;《新中医》;19801231(第2期);第30-31页 *
施今墨先生毕生用药经验（附有记忆口诀）;天地阴阳;《https://www.sohu.com/na/380650671_488272》;20200317;第1-8页，尤其是第4页方37 *
易磊.防胜于治：怎么做才能让孩子不感冒.《让孩子不上火不感冒不咳嗽不厌食》.上海科学技术文献出版社,2015,(第1版),第87-89页. *
近期流感凶猛，家里常备这些药，90%的儿童感冒不需要去医院就诊！;东莞儿童网;《https://www.sohu.com/a/286612711_370859》;20190104;第1-22页，尤其是第19-20页 *

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