CN114392476B - High-temperature superconductive magnetic suspension axial flow type blood pump - Google Patents
High-temperature superconductive magnetic suspension axial flow type blood pump Download PDFInfo
- Publication number
- CN114392476B CN114392476B CN202210049205.3A CN202210049205A CN114392476B CN 114392476 B CN114392476 B CN 114392476B CN 202210049205 A CN202210049205 A CN 202210049205A CN 114392476 B CN114392476 B CN 114392476B
- Authority
- CN
- China
- Prior art keywords
- superconductor
- blood pump
- axial flow
- magnetic bearing
- magnetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000008280 blood Substances 0.000 title claims abstract description 50
- 210000004369 blood Anatomy 0.000 title claims abstract description 50
- 239000000725 suspension Substances 0.000 title claims abstract description 23
- 239000002887 superconductor Substances 0.000 claims abstract description 79
- 230000005540 biological transmission Effects 0.000 claims abstract description 31
- 230000009471 action Effects 0.000 claims abstract description 9
- 238000005339 levitation Methods 0.000 claims description 23
- 238000009833 condensation Methods 0.000 claims description 10
- 238000001704 evaporation Methods 0.000 claims description 10
- 230000005494 condensation Effects 0.000 claims description 9
- 230000008020 evaporation Effects 0.000 claims description 9
- 239000000463 material Substances 0.000 claims description 9
- 238000005057 refrigeration Methods 0.000 claims description 5
- BTGZYWWSOPEHMM-UHFFFAOYSA-N [O].[Cu].[Y].[Ba] Chemical group [O].[Cu].[Y].[Ba] BTGZYWWSOPEHMM-UHFFFAOYSA-N 0.000 claims description 3
- 229910021521 yttrium barium copper oxide Inorganic materials 0.000 claims description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 16
- 238000013016 damping Methods 0.000 description 10
- 230000000694 effects Effects 0.000 description 8
- 238000000034 method Methods 0.000 description 8
- 229910052757 nitrogen Inorganic materials 0.000 description 8
- 230000008901 benefit Effects 0.000 description 7
- 208000007536 Thrombosis Diseases 0.000 description 6
- 210000002376 aorta thoracic Anatomy 0.000 description 6
- 239000007788 liquid Substances 0.000 description 6
- 206010019280 Heart failures Diseases 0.000 description 5
- 210000005240 left ventricle Anatomy 0.000 description 5
- 230000008569 process Effects 0.000 description 5
- 206010018910 Haemolysis Diseases 0.000 description 4
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical group [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 4
- 229910000831 Steel Inorganic materials 0.000 description 4
- 239000004020 conductor Substances 0.000 description 4
- 230000008588 hemolysis Effects 0.000 description 4
- -1 polypropylene Polymers 0.000 description 4
- 239000010959 steel Substances 0.000 description 4
- 239000004642 Polyimide Substances 0.000 description 3
- 238000005299 abrasion Methods 0.000 description 3
- 210000000709 aorta Anatomy 0.000 description 3
- 210000001765 aortic valve Anatomy 0.000 description 3
- 238000010276 construction Methods 0.000 description 3
- 210000001105 femoral artery Anatomy 0.000 description 3
- 238000007667 floating Methods 0.000 description 3
- 230000004907 flux Effects 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 230000010412 perfusion Effects 0.000 description 3
- 229920001721 polyimide Polymers 0.000 description 3
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 3
- 239000004810 polytetrafluoroethylene Substances 0.000 description 3
- 229920002379 silicone rubber Polymers 0.000 description 3
- 239000004945 silicone rubber Substances 0.000 description 3
- 238000004804 winding Methods 0.000 description 3
- 229910000976 Electrical steel Inorganic materials 0.000 description 2
- QJVKUMXDEUEQLH-UHFFFAOYSA-N [B].[Fe].[Nd] Chemical compound [B].[Fe].[Nd] QJVKUMXDEUEQLH-UHFFFAOYSA-N 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 238000009940 knitting Methods 0.000 description 2
- 229910001172 neodymium magnet Inorganic materials 0.000 description 2
- 239000002861 polymer material Substances 0.000 description 2
- 230000005855 radiation Effects 0.000 description 2
- 230000000087 stabilizing effect Effects 0.000 description 2
- 229910001220 stainless steel Inorganic materials 0.000 description 2
- 239000010935 stainless steel Substances 0.000 description 2
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 229920000106 Liquid crystal polymer Polymers 0.000 description 1
- 239000004977 Liquid-crystal polymers (LCPs) Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 206010000891 acute myocardial infarction Diseases 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000003466 anti-cipated effect Effects 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000003205 diastolic effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 239000011810 insulating material Substances 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 229920000139 polyethylene terephthalate Polymers 0.000 description 1
- 239000005020 polyethylene terephthalate Substances 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- 238000009941 weaving Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/20—Type thereof
- A61M60/205—Non-positive displacement blood pumps
- A61M60/216—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
- A61M60/237—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/80—Constructional details other than related to driving
- A61M60/802—Constructional details other than related to driving of non-positive displacement blood pumps
- A61M60/818—Bearings
- A61M60/82—Magnetic bearings
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Mechanical Engineering (AREA)
- Anesthesiology (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Structures Of Non-Positive Displacement Pumps (AREA)
- External Artificial Organs (AREA)
Abstract
The application relates to the field of medical equipment, especially, relate to a high temperature superconductive magnetic suspension axial flow blood pump, include: the driving system, the impeller assembly and the transmission system for connecting the driving system and the impeller assembly are arranged in the transmission system, the transmission system comprises a magnetic bearing, a superconductor and a conveying conduit, the conveying conduit comprises an inner pipe, the magnetic bearing is connected with the inner pipe, the superconductor is connected on the conveying conduit, and the inner pipe is kept in a 'suspension' state under the action of the magnetic bearing and the superconductor.
Description
Technical Field
The application relates to the field of medical equipment, in particular to a high-temperature superconductive magnetic suspension axial flow blood pump.
Background
Currently, heart failure has high morbidity and mortality, which are important causes of death for most patients with cardiovascular diseases, and nearly 1.17 hundred million people worldwide suffer from the disease. Heart failure is totally called heart failure, namely, venous blood can not be sufficiently discharged out of the body due to the occurrence of dysfunction of systolic function or diastolic function of the heart, so that venous blood is accumulated, arterial blood supply is insufficient, and finally, the heart circulatory system is blocked, and the estimated incidence rate of acute myocardial infarction in China is about forty-five to fifteen parts per million, and the current rising trend is also presented. Since heart failure progresses slowly, most of heart failure is caused by the fact that after various symptoms of patients grow for many years, the heart gradually loses the blood pumping function, functions in all aspects gradually weaken, and the heart is enlarged, mainly the left ventricle is enlarged, so that the life quality and clinical treatment of the patients are greatly negatively affected. The existing treatment schemes comprise medication, auxiliary equipment and heart transplantation, but different treatment methods face great challenges, such as the existing axial flow blood pump mostly adopts sliding bearings, ball bearings and the like to provide radial support for the stable rotation of the blood pump, but due to the higher rotation speed of the blood pump, the abrasion residues and the heat generated by friction are higher along with the increase of the running time, and even though perfusion liquid is used for cooling and taking away part of abrasion matters, complications such as thrombus and the like are still easy to trigger.
Patent CN201410467663.4 describes a magnetic suspension axial flow blood pump, which is a pump-machine integration, and mainly comprises a pump shell, an iron core, a coil winding, a pump tube, a permanent magnetic bearing, an impeller, rotor magnetic steel, front and rear diversion blades, wherein a convex magnetic cone is embedded in the front end of an impeller hub, a magnetic cone with one end being a concave is embedded in the front diversion impeller hub, the two magnetic cones are both in axial magnetic directions, and like magnetic poles are opposite, and the two magnetic cones are matched into a pair of front permanent magnetic suspension bearings; the rear end of the impeller hub is embedded with a raised magnetic cone, the rear impeller hub is embedded with a magnetic cone with one end being a concave, the two magnetic cones are both in axial magnetic directions and have opposite magnetic poles with the same polarity, the two magnetic cones are matched into a pair of rear permanent magnet suspension bearings, and the two pairs of permanent magnet suspension bearings completely suspend the impeller; two ends of the permanent magnet rotor magnetic steel in the impeller hub are respectively provided with a soft magnet ring for shielding magnetic field interference of the rotor magnetic steel and the protruding magnetic cones at the two ends; the technical defect of the scheme is that: in order to ensure that the impeller is kept in a full-suspension state, an iron core and a coil winding are arranged in a pump shell of the blood pump, so that the weight and the volume of the blood pump are large, the load on the heart is heavy, and meanwhile, the problem that the hemolysis and even thrombus are easy to cause due to joule heat loss in the pump body is solved.
Accordingly, those skilled in the art have focused their efforts on developing a high temperature superconducting magnetic levitation axial flow blood pump that primarily addresses the following issues: the problems of high weight and large volume of the magnetic suspension axial flow blood pump and complications such as hemolysis, thrombus and the like caused by Joule heat loss.
Disclosure of Invention
The present application is presented in view of the above and other further concepts.
One of the purposes of the application is to overcome the defects of the prior art, and to solve the problems of hemolysis, thrombus and the like caused by large weight, large volume and large heat loss of a magnetic suspension axial flow blood pump, for example, the magnetic suspension axial flow blood pump is provided.
According to another aspect of the present application, there is provided a high temperature superconducting magnetic levitation axial flow blood pump, comprising: the device comprises a driving system, an impeller assembly and a transmission system connected with the driving system and the impeller assembly, wherein the transmission system comprises a magnetic bearing, a superconductor and a conveying conduit, the conveying conduit comprises an inner pipe, the magnetic bearing is connected with the inner pipe, the superconductor is connected to the conveying conduit, and the inner pipe is kept in a 'suspension' state under the action of the magnetic bearing and the superconductor.
According to an embodiment, the delivery catheter further comprises an outer sheath and a multi-lumen tube, the outer sheath being disposed at an outermost layer of the delivery catheter; and the superconductor is attached to the multilumen tubing.
According to an embodiment, the inner tube, the magnetic bearing and the superconductor are arranged inside-out in the cross-sectional direction of the delivery catheter; and the central axes of the inner tube, the magnetic bearing and the superconductor are overlapped.
According to an embodiment, the inner tube comprises a rotational shaft, a flexible transmission shaft and a driving shaft, wherein the rotational shaft, the flexible transmission shaft and the driving shaft are connected from the proximal end to the distal end.
According to an embodiment, the drive system comprises a motor, the impeller assembly comprising a blade; and the rotating shaft is connected with the motor, and the driving shaft is connected with the blade or integrally formed.
According to an embodiment, the motor comprises a motor shaft, which is fixedly connected with the rotating shaft.
According to an embodiment, the drive shaft is connected to the blade by an adhesive or interference fit.
According to one embodiment, the magnetic bearing is attached to the drive shaft and the superconductor is attached to the distal portion of the delivery catheter; and the superconductor is sleeved outside the magnetic bearing.
According to one embodiment, the magnetic bearing is attached to the rotating shaft and the superconductor is attached to the proximal portion of the delivery catheter; and the superconductor is sleeved outside the magnetic bearing.
According to one embodiment, the magnetic bearings are arranged in a matched mode with the superconductors, the number of the magnetic bearings is identical to that of the superconductors, and the number of the magnetic bearings is one, two or more.
According to an embodiment, the magnetic bearing may be provided on the impeller assembly, or at any position on the inner tube.
According to an embodiment, the transmission system further comprises a refrigeration device, a transfer device and a thermostatic holder; and the constant temperature retainer is arranged outside the superconducting body, the refrigerating device provides a cold source for the constant temperature retainer, and the transmitting device transmits the cold source.
According to one embodiment, the refrigerating device is a miniature low-temperature refrigerator, the performance of the refrigerating device is 2W@77K, the refrigerating device comprises a cold head, an expander, a compressor and an electric plug, the cold head has a temperature of 77K, a continuous cold source is provided for the constant-temperature retainer, the refrigerating device compresses heat through the compressor, the cold quantity is obtained in the expander, and the cold quantity is transferred in the cold head.
According to an embodiment, the refrigeration device comprises a compressor, an expander and a coldhead; the transfer device comprises an evaporation unit, a flexible unit and a condensation unit; and, the cold head is coupled with the evaporation unit, and the condensation unit is coupled with the constant temperature holder.
According to one embodiment, the transfer device is purged with nitrogen.
According to an embodiment, the cold source flows from the evaporation unit to the flexible unit, forming liquid nitrogen at the condensation unit.
According to an embodiment, nitrogen flows from the evaporation unit to the flexible unit, forming liquid nitrogen at the condensation unit.
According to an embodiment, the refrigeration device is a liquid nitrogen supply that supplies liquid nitrogen to the thermostatic holder to ensure low temperature of the superconductor.
According to an embodiment, the delivery device is disposed within the lumen of the multi-lumen tube.
According to an embodiment, the flexible unit is a flexible heat pipe.
According to an embodiment, the flexible heat pipe is made of a polymer material, and the polymer material includes polypropylene, polyimide, a liquid crystal polymer, polyethylene terephthalate and silicone rubber.
According to an embodiment, the drive train further comprises a vacuum holding device comprising a vacuum nozzle connected with the thermostat holder.
According to one embodiment, the superconductor is a yttrium barium copper oxide material; and the temperature maintained by the constant temperature holder is 77K and above, while it should be appreciated that any superconducting material having a critical temperature greater than 77K can be used.
According to one embodiment, the superconductor is of equal radial length to the magnetic bearing.
According to an embodiment, the thermostatic retainer is a sealing structure.
According to an embodiment, the constant temperature retainer shell is stainless steel material, and polyimide multi-layer is woven to inboard cloth to gilt in the weaving layer outside, the benefit of this design lies in: radiation heat leakage can be reduced.
According to an embodiment, a thermally conductive material is provided between the thermostatted holder and the superconductor.
According to an embodiment, after the constant temperature retainer is connected with the superconductor through the heat conducting material, the constant temperature retainer, the superconductor and the heat conducting material are all covered by the heat insulating material.
According to an embodiment, the thermally conductive material is a thermally conductive silicone grease or a thermally conductive pad.
According to one embodiment, the magnetic bearing comprises a concentrated magnet and a permanent magnet, and the superconductor provides magnetostatic levitation force for the magnetic bearing in a constant temperature 77k environment.
According to an embodiment, the focusing body and the permanent magnet are arranged at intervals.
According to one embodiment, the superconductor has a Missner effect and a pinning effect at the same time in a constant temperature 77k environment; the magnetic bearing forms diamagnetism under the action of the superconductor and provides magnetostatic levitation force, the pinning effect provides a stabilizing force for the magnetic bearing, and the restoring force and rigidity in the rotating process of the magnetic bearing depend on the pinning degree of magnetic flux; the design has the advantages that: the driving shaft and the rotating shaft connected with the magnetic bearing can be kept in a 'floating' state, the radial vibration suffered by the driving shaft and the rotating shaft is small, and the operation stability is high.
According to an embodiment, the magnetic bearing is a coil.
According to an embodiment, the poly-magnet is a silicon steel sheet.
According to an embodiment, the permanent magnet material is neodymium iron boron.
According to an embodiment, the transmission system further comprises a magnetic shaft support and a magnetic shaft support end cap, and the magnetic shaft support end cap cooperate to connect the magnetic bearing to the inner tube.
According to an embodiment, the magnetic bearing end cap seals the magnetic bearing.
According to one embodiment, the drive system further comprises a superconductor holder, the superconductor being connected to the delivery catheter by the superconductor holder.
According to an embodiment, the transmission system comprises a bearing seat, the magnetic bearing is connected with the driving shaft, and a gap of 0.1-0.2mm is kept between the magnetic bearing and the bearing seat.
According to one embodiment, the superconductor is coupled to the bearing mount.
According to an embodiment, the drive shaft and the flexible drive shaft are welded or glued.
According to an embodiment, the magnetic bearing is connected to the multilumen tubing.
According to one embodiment, the inner layer of the multilumen tubing is attached with a PTFE film or other wear resistant material.
According to an embodiment, the transmission system further comprises a damping member comprising a damping ring, the damping material of the damping ring being polytetrafluoroethylene or silicone rubber.
According to an embodiment, the blood pump further comprises a perfusion system that perfuses the delivery catheter with a wash solution or a glucose solution.
According to an embodiment, the perfusion system is a fully closed system.
According to an embodiment, the impeller assembly further comprises a support, and the support is sleeved outside the blade.
According to one embodiment, the stent has an adaptation, and the stent can expand or contract.
According to an embodiment, the bracket is connected to the bearing housing.
According to one embodiment, the stent is divided into an expanded state and a contracted state.
According to one embodiment, the impeller assembly enters the left ventricle via the femoral artery, descending aorta, aortic arch, ascending aorta, aortic valve.
According to an embodiment, the multilumen tubing, the flexible unit and the flexible transfer shaft are all self-adapting, and the delivery catheter bends during its entry into the left ventricle.
Compared with the prior art, the technical scheme of the application has the advantages that at least the following steps are included:
1. in the prior art, the magnetic suspension axial flow blood pump body is internally provided with magnetic steel, an iron core, a coil winding and other parts, so that the blood pump has large mass and large volume, the heart burden is increased, the safety and the stability are not enough, and complications such as blood dissolution and even thrombus are easy to occur due to Joule heat loss; in one embodiment of the invention, a high-temperature superconductive magnetic suspension axial flow blood pump is adopted, the blood pump comprises a driving system, an impeller assembly and a transmission system, wherein the transmission system comprises a magnetic bearing, a conveying conduit and a superconductor, the magnetic bearing forms diamagnetism under the action of the superconductor and provides static magnetic suspension force, the self-stabilization of a suspension position is ensured through a magnetic flux pinning effect, meanwhile, the magnetic bearing is connected with an inner pipe of the conveying conduit, the magnetic bearing is sleeved outside the inner pipe, and the inner pipe can be kept in a 'suspension' state under the drive of the magnetic bearing; on the other hand, because the current density of the superconductor magnet is higher than that of the conventional magnet, the blood pump does not need coils, iron cores or other parts, the quality and the volume of the blood pump are reduced, and the superconductor and the magnetic bearing have no joule heat loss, so that a magnetic field far greater than that of the conventional magnet can be obtained, and the efficiency is higher; in summary, the inner tube of the present application maintains a structure in a "suspended" state under the action of both the magnetic bearing and the superconductor, which is beneficial for the blood pump to enter the heart and to remain in the heart, and the blood pump will not generate heat loss and abrasion, which greatly reduces the problems of hemolysis and thrombus, improves the blood compatibility, is beneficial to prolong the service life of the blood pump, and further improves the survival rate of patients, and has great clinical significance.
2. According to the conception of the application, the superconductor needs to be sleeved outside the magnetic bearing, the conveying catheter is further provided with a multi-cavity tube, the superconductor and the magnetic bearing seat are connected to the multi-cavity tube, and the tube parts of the multi-cavity tube are arranged coaxially, so that the coincidence of the central axes of the magnetic bearing and the superconductor is realized, and the inner tube is connected with the magnetic bearing, so that the stable and balanced radial supporting force of the inner tube can be obtained, and the integrity and the stability of the blood pump are improved.
3. According to one conception of the present application, the inner tube includes a rotation shaft, a flexible transmission shaft and a driving shaft, the rotation shaft is connected with the motor, the driving shaft is connected with the paddle, and since the restoring force and rigidity provided by the high temperature superconductor are large, the driving shaft cannot vibrate or vibrate very little in the rotation process, so that the vibration of the paddle is also very little, thereby reducing the risk of rubbing the paddle with the inner side of the bracket, and the paddle can stably rotate in the blood pump movement process.
4. According to one conception of the application, the magnetic bearing and the superconductor are arranged in a matched mode, the magnetic bearing is arranged on the rotating shaft or the driving shaft or the impeller assembly, and the magnetic bearing can be arranged in a plurality of modes, so that stable radial supporting force is obtained in the process that the inner tube drives the blades, and the overall stability of the high-temperature superconductive magnetic suspension axial flow blood pump is improved.
5. According to the conception of this application, the magnetic bearing is connected in the axis of rotation, the axis of rotation has obtained stable radial holding power, and the axis of rotation is connected with the motor, realized the axis of rotation and has stabilized pivoted purpose under "suspension" state, simultaneously, the axis of rotation is connected with flexible drive shaft, the axis of rotation has steadily transmitted the power for flexible drive shaft, flexible drive shaft drives the drive shaft and rotates, at the axis of rotation, flexible drive shaft and drive shaft rotate the in-process, the three all can not receive the hindrance of conveying pipe, help the drive shaft to drive the stable rotation of paddle, structural design is ingenious, the practicality is strong.
Embodiments of the present application are capable of other advantageous technical effects not listed one by one, which may be described in part below and which will be anticipated and understood by those skilled in the art after reading the present application.
Drawings
The above-mentioned and other features and advantages of these embodiments, and the manner of attaining them, will become more apparent and the embodiments of the application will be better understood by reference to the following description taken in conjunction with the accompanying drawings, wherein:
FIGS. 1a to 1c are schematic views showing the overall structure of the high temperature superconductive magnetic levitation axial flow blood pump of the present invention, and the structure of the connection between the inner tube and the blade.
Fig. 2a to 2d are schematic structural views of an inner tube, a rotating shaft and a motor, a constant temperature retainer, a vacuum retainer and a damping member.
Fig. 3a to 3b are schematic structural views of the refrigerating apparatus and the transferring apparatus of the present invention.
Fig. 4 is another embodiment of the magnetic bearing and superconductor arrangement of the invention.
The features indicated by the numbers in the drawings are as follows:
1-drive system, 11-motor, 2-drive system, 21-delivery catheter, 211-inner tube, 2111-drive shaft, 2112-flexible drive shaft, 2113-rotation shaft, 212-multi-lumen tube, 213-outer sheath tube, 22-magnetic bearing, 221-magnet, 222-permanent magnet, 23-superconductor, 24-refrigeration device, 241-compressor, 242-expander, 243-coldhead, 25-transfer device, 251-evaporation unit, 252-flexible unit, 253-condensation unit, 26-thermostatted holder, 27-vacuum holding device, 28-shock absorbing member, 281-shock absorbing ring, 3-impeller assembly, 31-paddle, 32-mount.
Description of the embodiments
The details of one or more embodiments of the application are set forth in the accompanying drawings and the description below. Other features, objects, and advantages of the application will be apparent from the description and drawings, and from the claims.
It is to be understood that the illustrated and described embodiments are not limited in application to the details of construction and the arrangement of components set forth in the following description or illustrated in the drawings. The illustrated embodiments may be other embodiments and can be implemented or performed in various ways. Examples are provided by way of explanation, not limitation, of the disclosed embodiments. Indeed, it will be apparent to those skilled in the art that various modifications and variations can be made to the embodiments of the present application without departing from the scope or spirit of the disclosure. For example, features illustrated or described as part of one embodiment can be used with another embodiment to yield still a further embodiment. Accordingly, this disclosure covers such modifications and variations as come within the scope of the appended claims and their equivalents.
Also, it is to be understood that the phraseology and terminology used herein is for the purpose of description and should not be regarded as limiting. The use of "including," "comprising," or "having" and variations thereof herein is meant to encompass the items listed thereafter and equivalents thereof as well as additional items.
The present application will be described in more detail below with reference to various embodiments and examples of aspects of the present application.
In this application, the term "proximal" or "proximal" refers to the end or side closer to the operator and "distal" or "distal" refers to the end or side farther from the operator.
Example 1
As shown in fig. 1a to 1c, there is illustrated a high temperature superconducting magnetic levitation axial flow blood pump according to an embodiment of the present application, comprising: the drive system 1, the impeller assembly 3 and the transmission system 2 connecting the drive system 1 and the impeller assembly 3, wherein the transmission system 2 comprises a magnetic bearing 22, a superconductor 23 and a conveying conduit 21, the conveying conduit 21 comprises an inner tube 211, the magnetic bearing 22 is connected with the inner tube 211, the superconductor 23 is connected on the conveying conduit 21, and the inner tube 211 is kept in a 'suspended' state under the action of the magnetic bearing 22 and the superconductor 23.
In the first embodiment, the delivery catheter 21 further includes an outer sheath 213 and a multi-lumen tube 212, wherein the outer sheath 213 is disposed on the outermost layer of the delivery catheter 21; and, the superconductor 23 is attached to the multilumen tubing 212, as shown in fig. 1 c.
In the first embodiment, the inner tube 211 includes a rotation shaft 2113, a flexible transmission shaft 2112, and a driving shaft 2111, and the rotation shaft 2113, the flexible transmission shaft 2112, and the driving shaft 2111 are connected from the proximal end toward the distal end, as shown in fig. 2 a.
In the first embodiment, the driving system 1 includes a motor 11, and the impeller assembly 3 includes a blade 31; the rotation shaft 2113 is connected to the motor 11, and the drive shaft 2111 is connected to the paddle 31.
In the first embodiment, the magnetic bearing 22 is connected to the rotation shaft 2113, and the superconductor 23 is connected to the proximal end portion of the delivery catheter 21; and, the superconductor 23 is sleeved outside the magnetic bearing 22, as shown in fig. 2 b.
In the first embodiment, the magnetic bearing 22 is connected to the drive shaft 2111, and the superconductor 23 is connected to the distal end portion of the delivery catheter 21; the superconductor 23 is sleeved outside the magnetic bearing 22, as shown in fig. 1 c.
In the first embodiment, the magnetic bearings 22 and the superconductors 23 are configured in a matching manner, and the driving shaft 2111 is provided with two magnetic bearings 22 and two superconductors 23.
In the first embodiment, the poly-magnet 221 is a silicon steel sheet, and the permanent magnet 222 is made of neodymium iron boron.
In the first embodiment, the transmission system 2 further includes a magnetic bearing and a magnetic bearing end cap, the magnetic bearing and the magnetic bearing end cap cooperate to connect the magnetic bearing 22 to the inner tube 211, and the magnetic bearing 22 end cap seals the magnetic bearing 22.
In one embodiment, the drive system 2 further includes a superconductor holder, and the superconductor 23 is coupled to the multi-lumen tube 212 via the superconductor holder.
In the first embodiment, the transmission system 2 includes a bearing housing, the magnetic bearing 22 is connected to the drive shaft 2111, a gap of 0.1-0.2mm is maintained between the magnetic bearing 22 and the bearing housing, and the superconductor 23 is connected to the bearing housing.
In the first embodiment, the transmission system 2 further includes a refrigerating device 24, a transmitting device 25 and a constant temperature retainer 26; and, the said thermostatted device 26 is set up outside the said superconductor 23, the said refrigerating plant 24 provides the cold source for the said thermostatted device 26, the said transfer device 25 transmits the cold source.
In the first embodiment, the refrigerating device 24 includes a compressor 241, an expander 242 and a cold head 243, as shown in fig. 3 a; the transfer device 25 comprises an evaporation unit 251, a flexible unit 252 and a condensation unit 253, as shown in fig. 3 b; and, the cold head 243 is coupled with the evaporation unit 251, and the condensation unit 253 is coupled with the thermostat holder 26.
In the first embodiment, nitrogen is introduced into the transfer device 25, the flexible unit 252 is a flexible heat pipe, the flexible unit 252 is disposed in the multi-cavity tube 212, the cold source flows from the evaporation unit 251 to the flexible unit 252, and liquid nitrogen is formed in the condensation unit 253.
In the first embodiment, the transmission system 2 further includes a damping member 28, where the damping member 28 includes a damping ring 281, and as shown in fig. 2c and 2d, the damping material of the damping ring 281 is polytetrafluoroethylene or silicone rubber.
In the first embodiment, the transmission system 2 further includes a vacuum holding device 27, and the vacuum holding device 27 includes a vacuum suction nozzle 271, and the vacuum suction nozzle 271 is connected with the thermostat 26.
In the first embodiment, the casing of the thermostat holder 26 is made of stainless steel, the inner side is provided with polyimide multi-layer knitting, and the outer side of the knitting layer is plated with gold, so that the design has the following advantages: radiation heat leakage can be reduced.
In the first embodiment, the superconductor 23 is made of yttrium barium copper oxide; and, the temperature maintained by the constant temperature holder 26 is 77K and above, while it should be understood that any superconducting material having a critical temperature greater than 77K can be used.
In the first embodiment, the magnetic bearing 22 includes a focusing body 221 and a permanent magnet 222, and the superconductor 23 provides magnetostatic levitation force for the magnetic bearing 22 under a constant temperature 77k environment.
In the first embodiment, the superconductor 23 has a meissner effect and a pinning effect at the same time in a constant temperature 77k environment; the magnetic bearing 22 forms diamagnetism under the action of the superconductor 23 and provides magnetostatic levitation force, the pinning effect provides a stabilizing force for the magnetic bearing 22, and the restoring force and rigidity in the rotation process of the magnetic bearing 22 depend on the pinning degree of magnetic flux; the design has the advantages that: the drive shaft 2111 and the rotary shaft 2113 connected to the magnetic bearing 22 can be kept in a "floating" state, and the radial vibration received by the drive shaft 2111 and the rotary shaft 2113 is small, and the operation temperature is high.
In the first embodiment, the impeller assembly 3 further includes a bracket 32, and the bracket 32 is sleeved outside the blade 31.
In the first embodiment, the impeller assembly 3 enters the left ventricle through femoral artery, descending aorta, aortic arch, ascending aorta and aortic valve.
An exemplary implantation operation procedure of the high temperature superconductive magnetic levitation axial flow blood pump of the first embodiment is as follows:
1. the impeller assembly 3 enters the left ventricle through femoral artery, descending aorta, aortic arch, ascending aorta and aortic valve, and the bracket 32 is supported across the valve;
2. starting the refrigerating device 24, the constant temperature retainer 26 and the vacuum retaining device 27, wherein the semiconductor is in a 77k environment, and the inner tube 211 is kept in a 'floating' state;
3. the motor 11 of the driving system 1 is started, the motor 11 drives the inner tube 211 to rotate, and the paddle 31 is driven by the driving shaft 2111 to rotate.
Example two
The second embodiment is substantially the same as the first embodiment except for the arrangement position of the magnetic bearing 22 and the superconductor 23.
As shown in fig. 1a and 4, a high temperature superconducting magnetic levitation axial flow blood pump according to an embodiment of the present application is illustrated, comprising: the drive system 1, the impeller assembly 3 and the transmission system 2 connecting the drive system 1 and the impeller assembly 3, wherein the transmission system 2 comprises a magnetic bearing 22, a superconductor 23 and a conveying conduit 21, the conveying conduit 21 comprises an inner tube 211, the magnetic bearing 22 is connected with the inner tube 211, the superconductor 23 is connected on the conveying conduit 21, and the inner tube 211 is kept in a 'suspended' state under the action of the magnetic bearing 22 and the superconductor 23.
In the second embodiment, the driving shaft 2111 and the paddle 31 are integrally formed, and the most distal end of the driving shaft 2111 is located at the distal end of the paddle 31.
In the second embodiment, the magnetic bearing 22 and the superconductor 23 are disposed on both sides of the paddle 31, the magnetic bearing 22 is connected to the driving shaft 2111, and the superconductor 23 is disposed on the bracket 32.
In this regard, the related construction and conception of the second embodiment is similar to that of the first embodiment, and thus a description thereof will not be repeated here.
The foregoing description of several embodiments of the present application has been presented for purposes of illustration. It is not intended to be exhaustive or to limit the application to the precise configuration, construction and/or steps disclosed, and obviously many modifications and variations are possible in light of the above teaching. The scope of the invention and all equivalents are intended to be defined by the appended claims.
Claims (13)
1. A high temperature superconducting magnetic levitation axial flow blood pump comprising: the driving system, impeller subassembly with connect the driving system with the transmission system of impeller subassembly, its characterized in that: the transmission system comprises a magnetic bearing, a superconductor and a conveying conduit, wherein the conveying conduit comprises an inner pipe, the magnetic bearing is connected with the inner pipe, the superconductor is connected to the conveying conduit, the superconductor is sleeved outside the magnetic bearing, the transmission system further comprises a refrigerating device, a constant temperature retainer and a vacuum retaining device connected with the constant temperature retainer, the constant temperature retainer is arranged outside the superconductor, the refrigerating device provides a cold source for the constant temperature retainer, the inner pipe comprises a rotating shaft, a flexible transmission shaft and a driving shaft, the rotating shaft, the flexible transmission shaft and the driving shaft are connected from the proximal end to the distal end, and the driving shaft is kept in a 'suspension' state under the action of the magnetic bearing and the superconductor.
2. The high temperature superconducting magnetic levitation axial flow blood pump of claim 1 wherein the delivery catheter further comprises an outer sheath and a multi-lumen tube, the outer sheath being disposed on an outermost layer of the delivery catheter; and the superconductor is attached to the multilumen tubing.
3. The high-temperature superconducting magnetic levitation axial flow blood pump according to claim 1 or 2, wherein the inner tube, magnetic bearing and superconductor are arranged from inside to outside in a cross-sectional direction of the delivery conduit; and the central axes of the inner tube, the magnetic bearing and the superconductor are overlapped.
4. The high temperature superconducting magnetic levitation axial flow blood pump of claim 1 wherein the drive system comprises a motor and the impeller assembly comprises paddles; and the rotating shaft is connected with the motor, and the driving shaft is connected with the blade or integrally formed.
5. The high temperature superconducting magnetic levitation axial flow blood pump of claim 1 wherein the magnetic bearing is coupled to the drive shaft and the superconductor is coupled to a distal portion of the delivery catheter.
6. The high temperature superconducting magnetic levitation axial flow blood pump of claim 1 wherein the magnetic bearing is coupled to the rotating shaft and the superconductor is coupled to a proximal portion of the delivery catheter.
7. The high-temperature superconductive magnetic suspension axial flow blood pump according to claim 1, wherein the magnetic bearings are arranged in a matching way with the superconductors, the number of the magnetic bearings is consistent with that of the superconductors, and the number of the magnetic bearings is one, two or more.
8. The high temperature superconducting magnetic levitation axial flow blood pump of claim 7 wherein the magnetic bearing can be disposed on the impeller assembly or on any position on the inner tube.
9. The high temperature superconducting magnetic levitation axial flow blood pump of claim 1 wherein the transmission system further comprises a transfer device; and the transmitting device transmits the cold source.
10. The high temperature superconducting magnetic levitation axial flow blood pump of claim 9 wherein the refrigeration device comprises a compressor, an expander and a coldhead; the transfer device comprises an evaporation unit, a flexible unit and a condensation unit; and, the cold head is coupled with the evaporation unit, and the condensation unit is coupled with the constant temperature holder.
11. The high temperature superconducting magnetic levitation axial flow blood pump of claim 9 wherein the drive system further comprises a vacuum holding device comprising a vacuum pump nozzle connected to the thermostatic retainer.
12. The high temperature superconducting magnetic levitation axial flow blood pump of claim 9 wherein the superconductor is yttrium barium copper oxide material; and the temperature maintained by the constant temperature retainer is 77k or more.
13. The high temperature superconducting magnetic levitation axial flow blood pump of claim 1 or 12 wherein the magnetic bearing comprises a concentrated magnet and a permanent magnet, the superconductor providing magnetostatic levitation force to the magnetic bearing in a constant temperature 77k environment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210049205.3A CN114392476B (en) | 2022-01-17 | 2022-01-17 | High-temperature superconductive magnetic suspension axial flow type blood pump |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210049205.3A CN114392476B (en) | 2022-01-17 | 2022-01-17 | High-temperature superconductive magnetic suspension axial flow type blood pump |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN114392476A CN114392476A (en) | 2022-04-26 |
| CN114392476B true CN114392476B (en) | 2024-02-06 |
Family
ID=81231955
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210049205.3A Active CN114392476B (en) | 2022-01-17 | 2022-01-17 | High-temperature superconductive magnetic suspension axial flow type blood pump |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114392476B (en) |
Citations (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0712126A (en) * | 1993-06-23 | 1995-01-17 | Ntn Corp | Superconductive bearing device |
| US6302661B1 (en) * | 1996-05-03 | 2001-10-16 | Pratap S. Khanwilkar | Electromagnetically suspended and rotated centrifugal pumping apparatus and method |
| WO2005030296A2 (en) * | 2003-09-25 | 2005-04-07 | Medforte Research Foundation | Axial-flow blood pump with magnetically suspended, radially and axially stabilized impeller |
| JP2008283803A (en) * | 2007-05-11 | 2008-11-20 | Railway Technical Res Inst | Superconducting magnet for magnetic-levitation railway vehicle |
| JP2009148709A (en) * | 2007-12-20 | 2009-07-09 | Niigata Univ | Magnetic levitation rotation apparatus |
| CN104208763A (en) * | 2014-09-15 | 2014-12-17 | 长治市久安人工心脏科技开发有限公司 | Magnetic suspension axial flow type blood pump |
| JP2015004275A (en) * | 2013-06-19 | 2015-01-08 | 株式会社前川製作所 | Superconduction non-contact compression equipment |
| CN111655307A (en) * | 2018-01-31 | 2020-09-11 | 心脏器械股份有限公司 | Axial blood pump with impeller flushing operation |
| CN112791305A (en) * | 2021-01-22 | 2021-05-14 | 苏州心擎医疗技术有限公司 | Blood pump and power transmission assembly thereof |
| CN112994525A (en) * | 2021-02-26 | 2021-06-18 | 河南理工大学 | Superconductive-permanent magnet mixed magnetic suspension low-temperature disc type immersed pump |
| CN113546297A (en) * | 2021-07-14 | 2021-10-26 | 清华大学 | Implanted miniature magnetic suspension axial flow blood pump |
| CN113599692A (en) * | 2021-08-05 | 2021-11-05 | 深圳核心医疗科技有限公司 | Blood pump |
| CN113769259A (en) * | 2021-09-24 | 2021-12-10 | 北京航空航天大学 | Extracorporeal circulation magnetic suspension axial flow blood pump |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20010039369A1 (en) * | 1999-12-14 | 2001-11-08 | Terentiev Alexandre N. | Blood pump system |
| US8075472B2 (en) * | 2007-05-03 | 2011-12-13 | Leviticus-Cardio Ltd. | Permanent ventricular assist device for treating heart failure |
| JP5932375B2 (en) * | 2012-02-06 | 2016-06-08 | メドテックハート株式会社 | Blood pump |
-
2022
- 2022-01-17 CN CN202210049205.3A patent/CN114392476B/en active Active
Patent Citations (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0712126A (en) * | 1993-06-23 | 1995-01-17 | Ntn Corp | Superconductive bearing device |
| US6302661B1 (en) * | 1996-05-03 | 2001-10-16 | Pratap S. Khanwilkar | Electromagnetically suspended and rotated centrifugal pumping apparatus and method |
| WO2005030296A2 (en) * | 2003-09-25 | 2005-04-07 | Medforte Research Foundation | Axial-flow blood pump with magnetically suspended, radially and axially stabilized impeller |
| JP2008283803A (en) * | 2007-05-11 | 2008-11-20 | Railway Technical Res Inst | Superconducting magnet for magnetic-levitation railway vehicle |
| JP2009148709A (en) * | 2007-12-20 | 2009-07-09 | Niigata Univ | Magnetic levitation rotation apparatus |
| JP2015004275A (en) * | 2013-06-19 | 2015-01-08 | 株式会社前川製作所 | Superconduction non-contact compression equipment |
| CN104208763A (en) * | 2014-09-15 | 2014-12-17 | 长治市久安人工心脏科技开发有限公司 | Magnetic suspension axial flow type blood pump |
| CN111655307A (en) * | 2018-01-31 | 2020-09-11 | 心脏器械股份有限公司 | Axial blood pump with impeller flushing operation |
| CN112791305A (en) * | 2021-01-22 | 2021-05-14 | 苏州心擎医疗技术有限公司 | Blood pump and power transmission assembly thereof |
| CN112994525A (en) * | 2021-02-26 | 2021-06-18 | 河南理工大学 | Superconductive-permanent magnet mixed magnetic suspension low-temperature disc type immersed pump |
| CN113546297A (en) * | 2021-07-14 | 2021-10-26 | 清华大学 | Implanted miniature magnetic suspension axial flow blood pump |
| CN113599692A (en) * | 2021-08-05 | 2021-11-05 | 深圳核心医疗科技有限公司 | Blood pump |
| CN113769259A (en) * | 2021-09-24 | 2021-12-10 | 北京航空航天大学 | Extracorporeal circulation magnetic suspension axial flow blood pump |
Non-Patent Citations (2)
| Title |
|---|
| 中国科学技术协会主编，中国电工技术学会编著.2012-2013电气工程学科发展报告.中国科学技术出版社,2014,(第1版),205-217. * |
| 吕毅等.临床心脏病学.吉林科学技术出版社,2017,(第1版),328-333. * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN114392476A (en) | 2022-04-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US11786700B2 (en) | Catheter device | |
| US4908012A (en) | Chronic ventricular assist system | |
| JP3570726B2 (en) | Intravascular blood pump | |
| CN114215792B (en) | Micropump with totally-enclosed cleaning fluid circulation system | |
| US6336939B1 (en) | Auxiliary artificial heart of an embedded type | |
| US5613935A (en) | High reliability cardiac assist system | |
| Yamazaki et al. | EVAHEART™: An implantable centrifugal blood pump for long-term circulatory support | |
| CA1240802A (en) | High-capacity intravascular blood pump utilizing percutaneous access | |
| EP1464348B1 (en) | Sealless rotary blood pump with passive magnetic radial bearings and blood immersed axial bearings | |
| US20110238172A1 (en) | Blood pump | |
| CN115282468A (en) | Intervention type blood pump | |
| WO2017133425A1 (en) | Right ventricular assist device | |
| Sieß et al. | Concept, realization, and first in vitro testing of an intraarterial microaxial blood pump | |
| CN114392476B (en) | High-temperature superconductive magnetic suspension axial flow type blood pump | |
| WO2024131263A1 (en) | Cleaning system capable of continuously flushing blood pump | |
| CN111097077B (en) | External magnetic drive liquid suspension axial-flow type blood pump | |
| Li et al. | Development of a new left ventricular assist device: the dynamic aortic valve | |
| WO2024037554A1 (en) | Catheter pump | |
| CN218940913U (en) | Slotless permanent magnet motor for artificial heart pump and artificial heart pump | |
| Qian et al. | Use of aortic valvo-pumps placed in valve annulus for long-term left ventricular assist | |
| CN219355088U (en) | Blood vessel wall supporting type aortic blood pumping device | |
| US20230201559A1 (en) | Moisture absorbing seal for catheter fluid system | |
| CN116966413A (en) | Blood pump and heart assist device | |
| Yamazaki et al. | The “Cool Seal” Concept: A Low-Temperature Mechanical Seal with Recirculating Purge System for Rotary Blood Pumps | |
| CN116726376A (en) | Be used for external artifical bilobed wheel magnetic suspension blood pump |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |