CN114375958A - Nematicidal composition containing Cyclobutrifluram and application thereof - Google Patents
Nematicidal composition containing Cyclobutrifluram and application thereof Download PDFInfo
- Publication number
- CN114375958A CN114375958A CN202210081714.4A CN202210081714A CN114375958A CN 114375958 A CN114375958 A CN 114375958A CN 202210081714 A CN202210081714 A CN 202210081714A CN 114375958 A CN114375958 A CN 114375958A
- Authority
- CN
- China
- Prior art keywords
- active ingredient
- cyclobutrifluram
- nematode
- nematicidal composition
- mass ratio
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- GBFKIHJZPMECCF-BXUZGUMPSA-N (R,R)-cyclobutrifluram Chemical compound FC(F)(F)C1=NC=CC=C1C(=O)N[C@H]1[C@@H](C=2C(=CC(Cl)=CC=2)Cl)CC1 GBFKIHJZPMECCF-BXUZGUMPSA-N 0.000 title claims abstract description 66
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- ONCZDRURRATYFI-TVJDWZFNSA-N trifloxystrobin Chemical compound CO\N=C(\C(=O)OC)C1=CC=CC=C1CO\N=C(/C)C1=CC=CC(C(F)(F)F)=C1 ONCZDRURRATYFI-TVJDWZFNSA-N 0.000 claims abstract description 36
- JEFUQUGZXLEHLD-UHFFFAOYSA-N n-[(5-chloro-2-propan-2-ylphenyl)methyl]-n-cyclopropyl-3-(difluoromethyl)-5-fluoro-1-methylpyrazole-4-carboxamide Chemical compound CC(C)C1=CC=C(Cl)C=C1CN(C(=O)C=1C(=NN(C)C=1F)C(F)F)C1CC1 JEFUQUGZXLEHLD-UHFFFAOYSA-N 0.000 claims abstract description 34
- CFGPESLNPCIKIX-UHFFFAOYSA-N [2-[ethoxy(propylsulfanyl)phosphoryl]oxyphenyl] n-methylcarbamate Chemical compound CCCSP(=O)(OCC)OC1=CC=CC=C1OC(=O)NC CFGPESLNPCIKIX-UHFFFAOYSA-N 0.000 claims abstract description 20
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- 125000001995 cyclobutyl group Chemical group [H]C1([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 239000002283 diesel fuel Substances 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- YDEXUEFDPVHGHE-GGMCWBHBSA-L disodium;(2r)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Na+].[Na+].COC1=CC=CC(C[C@H](CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O YDEXUEFDPVHGHE-GGMCWBHBSA-L 0.000 description 1
- VVSMKOFFCAJOSC-UHFFFAOYSA-L disodium;dodecylbenzene;sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O.CCCCCCCCCCCCC1=CC=CC=C1 VVSMKOFFCAJOSC-UHFFFAOYSA-L 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- GVGUFUZHNYFZLC-UHFFFAOYSA-N dodecyl benzenesulfonate;sodium Chemical compound [Na].CCCCCCCCCCCCOS(=O)(=O)C1=CC=CC=C1 GVGUFUZHNYFZLC-UHFFFAOYSA-N 0.000 description 1
- 230000000835 effect on nematodes Effects 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- BEFDCLMNVWHSGT-UHFFFAOYSA-N ethenylcyclopentane Chemical compound C=CC1CCCC1 BEFDCLMNVWHSGT-UHFFFAOYSA-N 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 230000035558 fertility Effects 0.000 description 1
- 230000000855 fungicidal effect Effects 0.000 description 1
- 239000000417 fungicide Substances 0.000 description 1
- 150000002333 glycines Chemical class 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000000749 insecticidal effect Effects 0.000 description 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
- 244000144972 livestock Species 0.000 description 1
- 230000005923 long-lasting effect Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 235000019713 millet Nutrition 0.000 description 1
- 235000019426 modified starch Nutrition 0.000 description 1
- 229960003966 nicotinamide Drugs 0.000 description 1
- 235000005152 nicotinamide Nutrition 0.000 description 1
- 239000011570 nicotinamide Substances 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 235000006408 oxalic acid Nutrition 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 235000020232 peanut Nutrition 0.000 description 1
- 230000002688 persistence Effects 0.000 description 1
- 230000000361 pesticidal effect Effects 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000004584 polyacrylic acid Substances 0.000 description 1
- 229920005646 polycarboxylate Polymers 0.000 description 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 1
- 229920001451 polypropylene glycol Polymers 0.000 description 1
- 229920001296 polysiloxane Chemical class 0.000 description 1
- 235000019422 polyvinyl alcohol Nutrition 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- CHHHXKFHOYLYRE-STWYSWDKSA-M potassium sorbate Chemical compound [K+].C\C=C\C=C\C([O-])=O CHHHXKFHOYLYRE-STWYSWDKSA-M 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000000644 propagated effect Effects 0.000 description 1
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 210000000582 semen Anatomy 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000007873 sieving Methods 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000004299 sodium benzoate Substances 0.000 description 1
- 235000010234 sodium benzoate Nutrition 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 235000017550 sodium carbonate Nutrition 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 229940080264 sodium dodecylbenzenesulfonate Drugs 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 239000004328 sodium tetraborate Substances 0.000 description 1
- 235000010339 sodium tetraborate Nutrition 0.000 description 1
- PYODKQIVQIVELM-UHFFFAOYSA-M sodium;2,3-bis(2-methylpropyl)naphthalene-1-sulfonate Chemical compound [Na+].C1=CC=C2C(S([O-])(=O)=O)=C(CC(C)C)C(CC(C)C)=CC2=C1 PYODKQIVQIVELM-UHFFFAOYSA-M 0.000 description 1
- 238000005527 soil sampling Methods 0.000 description 1
- 239000004334 sorbic acid Substances 0.000 description 1
- 235000010199 sorbic acid Nutrition 0.000 description 1
- 229940075582 sorbic acid Drugs 0.000 description 1
- 238000009331 sowing Methods 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 239000004548 suspo-emulsion Substances 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
- 239000004563 wettable powder Substances 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P5/00—Nematocides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Plant Pathology (AREA)
- Environmental Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pest Control & Pesticides (AREA)
- General Health & Medical Sciences (AREA)
- Dentistry (AREA)
- Agronomy & Crop Science (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a nematicidal composition containing Cyclobutrifluram and application thereof, wherein the composition comprises an active ingredient A and an active ingredient B, the active ingredient A is Cyclobutrifluram, the active ingredient B is any one of trifloxystrobin, Isoflucypram or Phosphocarb, and the mass ratio of the active ingredient A to the active ingredient B is 1: 36-36: 1. The nematicidal composition can improve the actual prevention and control effect, effectively slow down the drug resistance of target pests and reduce the occurrence of soil-borne diseases.
Description
Technical Field
The invention belongs to the technical field of pesticide compounding, and particularly relates to a nematicidal composition containing Cyclobutrifluram and application thereof.
Background
Nematode disease is a plant disease caused by infestation and parasitism by plant parasitic nematodes. The damaged plant can affect normal growth and development because the nematode invades to absorb nutrition in the body; the secretion in the nematode metabolic process can also stimulate cells and tissues of host plants, cause plant deformity, and reduce the yield and quality of agricultural products. The more serious plant nematode diseases in China include root knot nematode diseases, soybean cyst nematode diseases, wheat grain nematode diseases, sweet potato stem nematode diseases, rice aphelenchoides besseyi, millet nematode diseases, pine wood nematode diseases, citrus half-piercing nematode diseases and the like of various crops such as peanuts and the like.
Cyclobutrifluram is a new nicotinamide insecticide developed by Jundada. Chemical name: n- [2- (2, 4-dichlorophenyl) cyclobutyl]-2- (trifluoromethyl) nicotinamide comprising 80% -100% of the (1S,2S) -enantiomer and 0-20% of the (1R,2R) -enantiomer; CAS accession number: 1460292-16-3; the molecular formula is as follows: c17H13CI2F3N2And O. The Cyclobutrifluram has the advantages of wide control spectrum, high efficiency, small using amount and easy use, can effectively control various nematodes and main fungal diseases, has high efficiency on root-knot nematodes, beet cyst nematodes, corn pratylenchus nematodes and the like on crops such as cucumbers, tomatoes, corns, beets and the like, can be used for soil treatment or seed treatment, and can control the nematodes and diseases in main crops and various environments for a long term.
Trifloxystrobin, international common name: trifluenfuronate, chemical name: 3,4, 4-trifluorobut-3-en-1-yl 2- (2-methoxyphenyl) -5-oxoylidenetetrahydrofuran-3-carboxylate; CAS number: 2074661-82-6; the molecular formula is as follows: c16H15F3O5(ii) a The trifloxystrobin has low toxicity, high safety and long lasting period, and has good application and development prospects.
Isoflucypram, a pyrazole carboxamide fungicide developed by Bayer crop science, Inc., under the chemical name: n- [ [ 5-chloro-2- (1-methylethyl) phenyl ] methyl ] -N-cyclopropyl-3- (difluoromethyl) -5-fluoro-1-methyl-1H-pyrazole-4-carboxamide, CAS accession No.: 1255734-28-1. Isoflucypram belongs to SDHI bactericides and has excellent effect on main leaf diseases such as leaf spot, net spot, stripe rust, leaf rust and the like.
Phosphocarb, CAS registry number 126069-54-3, belongs to the organophosphorus class of nematicides, chemical name: [2- [ ethoxy (propylthio) phosphoryl ] oxyphenyl ] N-methylcarbamate.
The pesticide containing a single active component has defects of different degrees in preventing and treating crop diseases and insect pests, is easy to generate drug resistance after being continuously used, and has the problems of narrow insecticidal spectrum, environmental pollution and the like. The applicant tests show that Isoflucypram has a certain control effect on nematodes, and the mixture of Cyclobutrifuram with different action mechanisms, trifloxystrobin, Isoflucypram or Phosphocarb has a better control effect on crop nematode diseases, is environment-friendly and has low toxicity to people and livestock.
Disclosure of Invention
The invention aims to provide a nematicidal composition with high activity to plant parasitic nematodes, which can improve the actual control effect, effectively slow down the generation of drug resistance of target pests and reduce the occurrence of soil-borne diseases.
In order to achieve the purpose, the invention is realized by the following technical scheme: the nematicidal composition comprises an active ingredient A and an active ingredient B, wherein the active ingredient A is Cycleutrifluram, the active ingredient B is any one of trifloxystrobin, Isoflucypram and Phosphocarb, and the mass ratio of the active ingredient A to the active ingredient B is 1: 36-36: 1.
Further, the active ingredient B is trifloxystrobin, and the mass ratio of the active ingredient A to the active ingredient B is 1: 19-19: 1;
further, the mass ratio of the Cyclobutrifluram to the trifloxystrobin is 1: 12-12: 1;
furthermore, the mass ratio of the Cyclobutrifluram to the trifloxystrobin is 1:12, 1:6, 1:2, 1:1, 2:1, 3:1, 4:1, 6:1, 7:1 and 12: 1;
further, the mass ratio of the Cyclobutrifluram to the trifloxystrobin is 1: 6-4: 1;
furthermore, the mass ratio of the Cyclobutrifluram to the trifloxystrobin is 1:6, 1:2, 1:1, 2:1, 3:1 and 4: 1;
further, the active ingredient B is Isoflucypram, and the mass ratio of the active ingredient A to the active ingredient B is 1: 30-30: 1;
further, the mass ratio of the Cyclobutrifluram to the Isoflucypram is 1: 5-5: 1;
furthermore, the mass ratio of the Cyclobutrifluram to the Isoflucypram is 1:5, 2:3, 1:2, 1:1, 2:1, 3:2 and 5: 1;
further, the active ingredient B is Phosphocarb, and the mass ratio of the active ingredient A to the active ingredient B is 1: 12-20: 1;
further, the mass ratio of the Cyclobutrifluram to the Phosphocarb is 1: 9-6: 1;
furthermore, the mass ratio of the Cyclobutrifluram to the Phosphocarb is 1:9, 1:6, 1:4, 1:1, 4:1 and 6: 1;
further, the total weight of the active ingredient A and the active ingredient B accounts for 0.1-80% of the composition;
furthermore, the total weight of the active ingredient A and the active ingredient B accounts for 0.1 to 60 percent of the composition;
further, the nematicidal composition comprises an agriculturally allowable auxiliary component besides the active component, wherein the auxiliary component is selected from one or more of a wetting agent, a dispersing agent, a thickening agent, a disintegrating agent, an emulsifying agent, an antifoaming agent, a preservative, a stabilizing agent, a synergist and a carrier;
further, the wetting agent is selected from one or a mixture of more of sodium dodecyl benzene sulfate, sodium dodecyl benzene sulfonate, saponin powder, alkyl sulfate, nekal BX, silkworm excrement, alkylphenol polyoxyethylene, fatty alcohol polyoxyethylene ether, alkanolamide polyoxyethylene ether and phosphate or sulfate thereof, and alkyl polyoxyethylene ether succinate sulfonate;
the dispersing agent is selected from one or a mixture of a plurality of polycarboxylate, lignosulfonate, naphthalene or alkyl naphthalene formaldehyde condensate sulfonate, calcium alkyl benzene sulfonate, alkylphenol polyoxyethylene phosphate, fatty alcohol polyoxyethylene polyoxypropylene ether, fatty alcohol polyoxypropylene ether and polymeric alkyl aryl sulfonate;
the emulsifier is selected from one or a mixture of a plurality of fatty alcohol polyoxyethylene ether, fatty alcohol ethylene oxide-propylene oxide copolymer, phenethyl phenol polyoxyethylene polyoxypropylene ether, alkylphenol polyoxyethylene ether, fatty amine polyoxyethylene ether, alkylbenzene sulfonate, styryl phenol polyoxyethylene ether and fatty acid polyoxyethylene ester;
the thickening agent is selected from one or a mixture of xanthan gum, polyvinyl alcohol, organic bentonite, magnesium aluminum silicate and carboxymethyl cellulose;
the disintegrating agent is selected from one or more of aluminum chloride, bentonite, sucrose, modified starch, cellulose, urea, sodium carbonate, sodium bicarbonate, sodium chloride, sodium sulfate, citric acid and tartaric acid;
the antifreezing agent is a mixture consisting of one or more of alcohols, alcohol ethers and inorganic salts;
the defoaming agent is selected from silicone oil and C10～C20Saturated fatty acid compound, C8～C10One or more of fatty alcohol compounds or silicone compounds;
the solvent is selected from one or a mixture of more of benzene, toluene, xylene, methanol, ethanol, isopropanol, N-butanol, diesel oil, N-dimethylformamide, cyclohexanone, ethyl acetate, N-methylpyrrolidone, propanol, butanol, ethylene glycol, diethylene glycol, ethylene glycol methyl ether, butyl ether, solvent oil, vegetable oil derivatives and deionized water;
the preservative is selected from one or a mixture of more of sorbic acid, sorbic acid sodium salt, sorbic acid potassium salt, benzoic acid sodium salt, parahydroxybenzoic acid sodium salt and parahydroxybenzoic acid methyl ester;
the stabilizer is selected from one or a mixture of more of oxalic acid, succinic acid, adipic acid, borax and epoxidized vegetable oil;
the warning color is selected from any one or more of red, yellow, blue, green and purple;
the film forming agent is selected from one or more of sodium carboxymethyl starch, cellulose derivatives (sodium carboxymethyl cellulose, sodium alginate and polyvinyl alcohol) and polyacrylic acid;
the carrier is selected from one or a mixture of more of kaolin, bentonite, attapulgite, light calcium carbonate, diatomite and white carbon black;
furthermore, the composition can be prepared into any agriculturally allowable preparation formulation, including any one of powder, wettable powder, microcapsule suspending agent, water dispersible granule, soluble tablet, soluble powder, dispersible oil suspending agent, missible oil, emulsion in water, suspending agent, suspoemulsion, soluble solution, microemulsion and seed treatment suspending agent;
furthermore, the preparation formulation is any one of granules, aqueous emulsion and seed treatment suspending agent.
The invention also discloses the application of the nematicidal composition containing the Cyclobutrifluram and/or the preparation thereof in preventing and controlling plant parasitic pests;
further, said plant parasitic pest is a plant parasitic nematode;
further, the plant parasitic nematodes are any one or more of root-knot nematodes (Meloidogyne), cyst nematodes (Heterodera), Aphelenchina, Stem nematodes (Ditylenchus), root-knot nematodes (Nacobbus) and root-rot nematodes (Pratylenchus), pine wood nematodes (Bursa Phellinus xylophilus);
further, the plant parasitism is root-knot nematode (Meloidogyne), cyst nematode (Heterodera);
further, the root knot nematode is Meloidogyne incognita (Kofold & White) Chitwood; the cyst nematode is soybean cyst nematode (Heterodera glycine).
Compared with the prior art, the invention has the following advantages:
1) the composition provided by the invention selects different mechanisms of medicaments for compound use, improves the control effect, reduces the pesticide application cost, delays the generation of drug resistance of pests, and provides a new solution for efficient control of nematodes.
2) The composition has low toxicity and low residual quantity in crops and soil, and effectively reduces environmental pollution and medicament residue.
Detailed Description
In order to better illustrate the effective control effect of the present invention, the above-mentioned examples are used to make the technical solutions, objects and advantages of the present invention more apparent, and the present invention is illustrated by the following specific examples, but the present invention is not limited to these examples. The effect experiment of the invention adopts a mode of combining indoor bioassay and field experiment.
Formulation preparation example:
preparation example the preparation process:
1. the preparation process of the seed treatment suspending agent comprises the following steps: the original drug, the auxiliary agent and the water are subjected to high-shear shearing, mixing and stirring uniformly according to the proportion, and then are subjected to sanding for 2.5 hours by a sanding machine to ensure that the average particle size reaches 1-5 microns, so that the seed coating suspending agent can be obtained.
2. The preparation process of the granules comprises the following steps: the preparation method comprises the steps of crushing and uniformly mixing the raw medicines, the dispersing agent and the auxiliary agent by adopting a coating granulation method to prepare mother powder, adding the mother powder and the carrier into a coating granulator together for stirring, adding the prepared binder aqueous solution while stirring, discharging after fully and uniformly mixing, drying and sieving to obtain the granules.
3. The preparation process of the aqueous emulsion comprises the following steps: mixing a surfactant, an antifreezing agent, a density regulator and water into a water phase, dissolving a raw pesticide by using a solvent, adding the dissolved raw pesticide into the water phase under stirring, adding a thickening agent and a preservative after stirring uniformly, continuously shearing for 10min, adding a defoaming agent, and stirring uniformly to form the O/W type aqueous emulsion.
Preparation example 1: 15% Cyclobutrifluram trifloxystrobin seed treatment suspending agent (1:2)
Preparation example 2: 12% Cyclobutrifluram Isoflucypram seed treatment suspending agent (1:1)
Preparation example 3: 8% Cyclobutrifluram trifloxystrobin granule (1:1)
| Components | Content (wt.) |
| Cyclobutrifluram | 4％ |
| Triflusalanoline | 4％ |
| Polycarboxylic acid sodium salt | 3％ |
| Potassium humate | 5％ |
| White carbon black | 10％ |
| Carboxymethyl cellulose | 3％ |
| Diatomaceous earth particles | Make up the balance |
Preparation example 4: 6% Cyclobutrifluram Isoflucypram granules (1:2)
Preparation example 5: 12% Cyclobutrifluram Phosphocarb granules (1:1)
| Components | Content (wt.) |
| Cyclobutrifluram | 6％ |
| Phosphocarb | 6％ |
| Lignosulfonic acid sodium salt | 5％ |
| Sodium alginate | 3％ |
| Attapulgite particles | Make up the balance |
Preparation example 6: 10% Cyclobutrifluram Phosphocarb emulsion in water (4:1)
| Components | Content (wt.) |
| Cyclobutrifluram | 8％ |
| Phosphocarb | 2％ |
| EO-PO block copolymer | 6％ |
| Cyclohexanone | 20％ |
| Xanthan gum | 0.2％ |
| Propylene glycol | 3％ |
| Urea | 3％ |
| Sodium benzoate | 0.5％ |
| Organic silicon defoaming agent | 0.2％ |
| Deionized water | Make up the balance |
Preparation example 7: 15% Cyclobutrifluram Isoflucypram emulsion in water (2:1)
| Components | Content (wt.) |
| Cyclobutrifluram | 10％ |
| Isoflucypram | 5％ |
| Alkylphenol ethoxylates | 3％ |
| Polyoxyethylene sorbitan monooleate | 3％ |
| Cyclohexanone | 25％ |
| Xanthan gum | 0.2％ |
| Ethylene glycol | 3％ |
| Urea | 3％ |
| Sorbic acid sodium salt | 0.5％ |
| Organic silicon defoaming agent | 0.5％ |
| Deionized water | Make up the balance |
Preparation example 8: 12% Cyclobutrifluram trifloxystrobin aqueous emulsion (3:1)
Laboratory bioassay test
Example 1: joint toxicity test of Cyclobutrifluram and trifloxystrobin or Isoflucypram on soybean cyst nematode
Test subjects: soybean cyst nematode (Heterodera glycine) is collected from a soybean test field with serious group morbidity, the collected diseased soil is separated into cysts by a floating method, and fresh mature cysts are picked out under a dissecting mirror and stored at 4 ℃ for later use.
Reagent to be tested: 90% of Cyclobutrifluram raw drug, 94.2% of Isoflucypram raw drug and 98% of trifloxystrobin raw drug, wherein the raw drugs are provided by group research and development centers.
Preparing a medicament: dissolving the above raw materials in acetone, and diluting with 0.1% Tween-80 aqueous solution. Each agent was set with 5 series of concentration gradients, and aqueous solutions without agent and with the same solvent content were used as controls.
Preparation of nematode suspension: and (3) placing the sterilized cysts into a sterilized hatching pool for hatching, and taking sterilized water as hatching liquid to ensure that the water slightly overflows the cysts. Incubating at 25 deg.C in incubator in dark condition to obtain two-instar larvae of consistent age, and making into nematode suspension, wherein each 1mL suspension contains no less than 100 head nematodes.
The test method comprises the following steps: and (3) sequentially sucking 3mL of liquid medicine into the test tube from low concentration to high concentration by using a pipette, and then sucking 3mL of prepared equivalent nematode suspension into the test tube, so that the liquid medicine and the nematode suspension are uniformly mixed in an equivalent manner. Using a pipette to pipette a certain volume of the mixed solution into the small holes of the multi-hole biochemical test plate, covering, repeating each treatment for 4 times, and using an aqueous solution containing no medicament and the same solvent content as a control. Culturing at 25 deg.C for 24 hr, examining activity of nematode, and calculating relative lethality of each agent treatment to nematode.
Test investigation: 1mL of the mixed solution is taken from each treatment, and the death condition of the nematodes is observed under a dissecting mirror, and the number of the nematodes observed in each repetition is not less than 100. The total number of nematodes investigated and the number of dead nematodes were recorded. Dead nematodes are often stiff and still cannot move in a bending manner when touched by a hair pin or a bamboo pin.
The calculation method comprises the following steps:
and calculating the mortality of each treatment according to the survey data, and calculating according to the following formula, wherein the calculation results are reserved to the last two decimal points:
if the control mortality rate is less than 5%, no correction is needed; if the control mortality is between 5% and 15%, correcting according to a mortality correction formula; control mortality was greater than 15%, and the test required redo.
Statistical analysis: according to the log values of the concentrations of the medicaments and the corresponding mortality, an IBM SPSS Statistics analysis system is used for analyzing to obtain a virulence regression line and LC50Value and correlation coefficient R2The activity of the test agent on the biological sample is evaluated.
Calculating co-toxicity coefficient (CTC) of the mixture according to Sun Yunpei method, and evaluating the combined action type.
CTC > 120 is shown as synergistic, CTC > 80 is shown as antagonistic, and CTC between 80 and 120 is shown as additive.
The co-toxicity coefficient (CTC value) of the combination was calculated as follows:
in the formula:
ATI-actually measured toxicity index of mixed agent;
S-LC of Standard insecticide50In milligrams per liter (mg/L);
LC of M-mixtures50In milligrams per liter (mg/L).
TTI＝TIA*PA+TIB*PB
In the formula:
TTI-mixture theory virulence index;
TIA-agent virulence index a;
PA-the percentage of agent a in the mixture in percent (%);
TIB-agent B virulence index;
PB-the percentage of the agent B in the mixture in percent (%).
In the formula:
CTC-co-toxicity coefficient;
ATI-actually measured toxicity index of mixed agent;
TTI-mixture theory virulence index.
The results of the tests are shown in the following table.
TABLE 1 Joint virulence determination test results for Cycloutriflam and trifloxystrobin combinations on Soybean cyst nematodes
As can be seen from the table 1, when the mass ratio of the Cyclobutrifuram to the trifloxystrobin is 1: 36-36: 1, the soybean cyst nematode is well controlled, and the combined action shows synergy; when the mass ratio of the Cyclobutrifluram to the trifloxystrobin is 1: 12-6: 1, the co-toxicity coefficient is more than 160, and the synergistic effect is remarkable; when the mass ratio of the Cyclobutrifluram to the trifloxystrobin is 1: 6-2: 1, the co-toxicity coefficient is greater than 180, and the synergistic effect is obvious; when the mass ratio of the Cyclobutrifluram to the trifloxystrobin is 1:2, the co-toxicity coefficient is 200.658 at most, which indicates that the compound of the Cyclobutrifluram and the trifloxystrobin has the best activity on the soybean cyst nematodes under the mass ratio.
TABLE 2 Joint virulence determination test results for soybean cyst nematodes with Cyclobutrifluram and Isoflucypram combinations
| Test reagent and proportion | Regression equation | Coefficient of correlation R2 | LC50(mg/L) | Co-toxicity coefficient |
| Clclobutrifluram(A) | y＝1.509x-0.920 | 0.993 | 4.071 | - |
| Isoflucypram(B) | y＝1.729x-1.615 | 0.990 | 8.592 | - |
| A:B＝1:16 | y＝1.673x-1.313 | 0.993 | 6.094 | 132.346 |
| A:B＝1:9 | y＝1.563x-1.128 | 0.997 | 5.267 | 146.824 |
| A:B＝1:5 | y＝1.797x-1.105 | 0.998 | 4.121 | 175.930 |
| A:B＝2:3 | y＝1.784x-0.868 | 0.994 | 3.066 | 194.040 |
| A:B＝1:1 | y＝1.762x-0.849 | 0.981 | 3.032 | 182.205 |
| A:B＝3:2 | y＝1.604x-0.740 | 0.985 | 2.893 | 178.232 |
| A:B＝5:1 | y＝1.639x-0.822 | 0.980 | 3.174 | 140.590 |
| A:B＝9:1 | y＝1.254x-0.645 | 0.990 | 3.269 | 131.450 |
| A:B＝16:1 | y＝1.384x-0.720 | 0.996 | 3.313 | 126.804 |
As can be seen from the table 2, when the mass ratio of the Cyclobutrifluram to the Isoflucypram is 1: 16-16: 1, the soybean cyst nematode is well controlled, and the combined action is shown as synergism; when the mass ratio of the Cyclobutrifluram to the Isoflucypram is 1: 9-5: 1, the co-toxicity coefficient is greater than 140, and the synergistic effect is obvious; when the mass ratio of the Cyclobutrifluram to the Isoflucypram is 1: 5-3: 2, the co-toxicity coefficient is greater than 170, and the synergistic effect is remarkable; when the mass ratio of the Cyclobutrifluram to the Isoflucypram is 2:3, the co-toxicity coefficient is 194.040 at most, which indicates that the combination of the Cyclobutrifluram and the Isoflucypram has the best activity on the soybean cyst nematodes under the mass ratio.
Example 2: combined virulence test of Cyclobutrifluram and trifloxystrobin or Isoflucypram or phosphonarb paired southern root-knot nematode
The test basis is as follows: reference is made to NY/T1833.1-2009 "indoor bioassay of pesticides test standard nematicides part 1: the method of soaking insects in the test of inhibiting plant pathogenic nematodes.
Test subjects: southern root knot nematode [ Meloidogyne incognita (Kofold & White) China ], was isolated from tomato root knot samples in greenhouses, the Qingdao city, the Mayowa Shifeng shop, and cultured and propagated on tomato live plants in the laboratory.
Reagent to be tested: 90% of Cyclobutrifluram technical, 94.2% of Isoflucypram technical, 98% of trifloxystrobin technical and 92% of phosphonocarb technical, wherein the technical is provided by group research and development centers.
Preparing a medicament: dissolving the above raw materials in acetone, and diluting with 0.1% Tween-80 aqueous solution. Each agent was set up with 5 series of concentration gradients, compared to an aqueous solution of solvent without the same amount of agent.
Preparation of nematode suspension: selecting root-knot nematode egg masses from tomato root knots with serious root-knot nematode morbidity, cleaning the root-knot nematode egg masses with clear water, placing the root-knot nematode egg masses on filter paper in a culture dish, adding a proper amount of distilled water, placing the filter paper in an incubator at 25 +/-1 ℃ for incubation and culture, collecting second-instar larvae with consistent instar stages after 24 hours to prepare a root-knot nematode suspension, wherein each 1mL of the suspension contains not less than 100 nematodes for later use.
The test method comprises the following steps: and (3) sequentially sucking 3mL of liquid medicine into the test tube from low concentration to high concentration by using a pipette, and then sucking 3mL of prepared equivalent nematode suspension into the test tube, so that the liquid medicine and the nematode suspension are uniformly mixed in an equivalent manner. Using a pipette to pipette a certain volume of the mixed solution into the small holes of the multi-hole biochemical test plate, covering, repeating each treatment for 4 times, and using the solvent aqueous solution without the same content of the medicament as a control. Culturing at 25 deg.C for 24 hr, examining activity of nematode, and calculating relative lethality of each agent treatment to nematode.
Test investigation: 1mL of the mixed solution is taken from each treatment, and the death condition of the nematodes is observed under a dissecting mirror, and the number of the nematodes observed in each repetition is not less than 100. The total number of nematodes investigated and the number of dead nematodes were recorded. Dead nematodes are often stiff and still cannot move in a bending manner when touched by a hair pin or a bamboo pin.
The calculation method comprises the following steps:
and calculating the mortality of each treatment according to the survey data, and calculating according to the following formula, wherein the calculation results are reserved to the last two decimal points:
if the control mortality rate is less than 5%, no correction is needed; if the control mortality is between 5% and 15%, correcting according to a mortality correction formula; control mortality was greater than 15%, and the test required redo.
Statistical analysis: according to the log values of the concentrations of the medicaments and the corresponding mortality, an IBM SPSS Statistics analysis system is used for analyzing to obtain a virulence regression line and LC50Value and correlation coefficient R2The activity of the test agent on the biological sample is evaluated.
Calculating co-toxicity coefficient (CTC) of the mixture according to Sun Yunpei method, and evaluating the combined action type.
CTC > 120 is shown as synergistic, CTC > 80 is shown as antagonistic, and CTC between 80 and 120 is shown as additive.
The co-toxicity coefficient (CTC value) of the combination was calculated as follows:
in the formula:
ATI-actually measured toxicity index of mixed agent;
S-LC of Standard insecticide50In milligrams per liter (mg/L);
LC of M-mixtures50In milligrams per liter (mg/L).
TTI＝TIA*PA+TIB*PB
In the formula:
TTI-mixture theory virulence index;
TIA-agent virulence index a;
PA-the percentage of agent a in the mixture in percent (%);
TIB-agent B virulence index;
PB-the percentage of the agent B in the mixture in percent (%).
In the formula:
CTC-co-toxicity coefficient;
ATI-actually measured toxicity index of mixed agent;
TTI-mixture theory virulence index.
The results of the tests are shown in the following table.
TABLE 3 Combined virulence assay results for Cyclobutrifluram and trifloxystrobin hybrid paired Meloidogyne incognita
As can be seen from the table 3, when the mass ratio of the Cyclobutrifuram to the trifloxystrobin is 1: 19-12: 1, the better control effect on Meloidogyne incognita is achieved, and the combined action is synergistic; when the mass ratio of the Cyclobutrifluram to the trifloxystrobin is 1: 12-7: 1, the co-toxicity coefficient is greater than 140, and the synergistic effect is obvious; when the mass ratio of the Cyclobutrifluram to the trifloxystrobin is 1: 6-4: 1, the co-toxicity coefficient is greater than 170, and the synergistic effect is remarkable; when the mass ratio of the Cyclobutrifluram to the trifloxystrobin is 3:1, the co-toxicity coefficient is 208.881 at most, which indicates that the combination of the Cyclobutrifluram and the trifloxystrobin has the best activity on the meloidogyne incognita at the mass ratio.
TABLE 4 Combined virulence assay results for Cyclobutrifluram and Isoflucypram mixed pair Meloidogyne incognita
| Test reagent and proportion | Regression equation | Coefficient of correlation R2 | LC50(mg/L) | Co-toxicity coefficient |
| Clclobutrifluram(A) | y＝1.507x-0.621 | 0.992 | 2.583 | - |
| Isoflucypram(B) | y＝1.402x-0.982 | 0.993 | 5.019 | - |
| A:B＝1:30 | y＝1.782x-1.082 | 0.987 | 4.047 | 120.356 |
| A:B＝1:20 | y＝1.67x-0.873 | 0.999 | 3.333 | 144.113 |
| A:B＝1:10 | y＝1.704x-0.811 | 0.997 | 2.992 | 154.501 |
| A:B＝1:5 | y＝1.980x-0.831 | 0.995 | 2.629 | 164.978 |
| A:B＝1:2 | y＝2.027x-0.659 | 0.998 | 2.114 | 180.633 |
| A:B＝1:1 | y＝1.957x-0.438 | 0.986 | 1.674 | 203.746 |
| A:B＝2:1 | y＝1.857x-0.394 | 0.998 | 1.630 | 189.052 |
| A:B＝5:1 | y＝1.829x-0.433 | 0.990 | 1.725 | 162.918 |
| A:B＝10:1 | y＝1.797x-0.499 | 0.985 | 1.895 | 142.598 |
| A:B＝20:1 | y＝1.717x-0.507 | 0.990 | 1.974 | 133.947 |
| A:B＝30:1 | y＝1.683x-0.534 | 0.988 | 2.076 | 126.401 |
As can be seen from the table 4, when the mass ratio of the Cyclobutrifluram to the Isoflucypram is 1: 30-30: 1, the better control effect on Meloidogyne incognita is achieved, and the combination effect is shown as synergism; when the mass ratio of the Cyclobutrifluram to the Isoflucypram is 1: 20-10: 1, the co-toxicity coefficient is greater than 140, and the synergistic effect is obvious; when the mass ratio of the Cyclobutrifluram to the Isoflucypram is 1: 5-5: 1, the co-toxicity coefficient is more than 160, and the synergistic effect is remarkable; when the mass ratio of the Cyclobutrifluram to the Isoflucypram is 1:1, the co-toxicity coefficient is maximum 203.746, which indicates that the combination of the Cyclobutrifluram and the Isoflucypram has the best activity on the meloidogyne incognita under the mass ratio.
TABLE 5 Combined virulence assay results for Meloidogyne incognita by Cyclobutrifuram and Phosphocarb compounding
| Test reagent and proportion | Regression equation | Coefficient of correlation R2 | LC50(mg/L) | Co-toxicity coefficient |
| Clclobutrifluram(A) | y＝1.981x-0.794 | 0.997 | 2.516 | - |
| Phosphocarb(B) | y＝1.759x-2.093 | 0.997 | 15.479 | - |
| A:B＝1:15 | y＝1.902x-1.938 | 0.993 | 10.441 | 112.141 |
| A:B＝1:12 | y＝1.608x-1.518 | 0.999 | 8.787 | 126.158 |
| A:B＝1:9 | y＝1.486x-1.188 | 0.995 | 6.304 | 162.050 |
| A:B＝1:6 | y＝1.477x-1.069 | 0.986 | 5.292 | 168.487 |
| A:B＝1:4 | y＝1.254x-0.788 | 0.989 | 4.250 | 179.375 |
| A:B＝1:1 | y＝1.418x-0.519 | 0.998 | 2.323 | 186.330 |
| A:B＝4:1 | y＝1.315x-0.272 | 0.983 | 1.610 | 187.714 |
| A:B＝6:1 | y＝1.481x-0.378 | 0.989 | 1.800 | 158.773 |
| A:B＝9:1 | y＝1.447x-0.427 | 0.997 | 1.973 | 139.177 |
| A:B＝15:1 | y＝1.316x-0.404 | 0.995 | 2.028 | 130.915 |
| A:B＝20:1 | y＝1.390x-0.453 | 0.998 | 2.118 | 123.725 |
As can be seen from the table 5, when the mass ratio of the Cyclobutrifuram to the Phosphocarb is 1: 12-20: 1, the better control effect on Meloidogyne incognita is achieved, and the combined action is shown as synergism; when the mass ratio of the Cyclobutrifluram to the Phosphocarb is 1: 9-6: 1, the co-toxicity coefficient is more than 150, and the synergistic effect is obvious; when the mass ratio of the Cyclobutrifluram to the Phosphocarb is 1: 4-4: 1, the co-toxicity coefficient is greater than 170, and the synergistic effect is remarkable; when the mass ratio of the Cyclobutrifluram to the Phosphocarb is 4:1, the cotoxicity coefficient is 187.714 at the maximum, which shows that the combination of the Cyclobutrifluram and the Phosphocarb has the best activity on the meloidogyne incognita at the mass ratio.
Test of field drug effect
Example 3: field efficacy test of compound of Cyclobutrifluram and trifloxystrobin or Isoflucypram on soybean cyst nematodes
The test basis is as follows: the test refers to GB/T17980.37-2000 'pesticide field efficacy test criterion (first) nematicide for preventing and treating cyst nematodes'.
Test site: in Xinning town of Ningliang county, Qingyang city, Gansu province, the soil quality of the test field is sandy loam, the fertility is good, and the soybean cyst nematode disease is serious when soybeans are continuously planted for many years.
Test crops and varieties: spring soybean, variety is Mengda 3. The soybeans are sown in 2019 in 5, 9 and harvested in 9, 30 days.
Medicament treatment: seed dressing treatment is carried out by using a seed treatment suspending agent, and then sowing is carried out after drying in the shade. The test agents and the dosages are shown in Table 6.
And (3) experimental design: the test is totally set with 6 groups of treatments, the test cells are arranged according to random block groups, and each cell has an area of 15m2Each treatment was repeated 4 times.
The investigation method comprises the following steps: collecting soil samples with soil sampling drill before test and after harvesting semen glycines, sampling 5 points per cell, and collecting 20cm per point3Soil, mixing, determining survival number of nematodes by water floating method, and taking average value of each point (number of live nematodes/20 cm)3). And calculating the prevention and treatment effect according to the change of the nematode population before and after treatment.
Soybean growth and yield survey: sampling is carried out at 5 random points in each cell in the soybean harvesting period, 4 soybean plants are dug at each point, the integrity of the root system is kept, the height and the root length of each soybean plant are respectively measured after the root system is washed by clear water, and the average value is recorded. And the yield of the soybeans is measured. The test results are shown in Table 7.
The cyst reduction rate and the prevention and treatment effect are calculated according to the following formulas:
TABLE 6 field efficacy test results of Cyclobutifluram and trifloxystrobin or Isoflucypripram combinations on Soy cyst nematodes
As can be seen from the field test results in the table above, the compound of Cyclobutrifluram and trifloxystrobin or Isoflucypram has good control effect on soybean cyst nematodes.
TABLE 7 results of experiments on the effect of Cyclobutrifluram and trifloxystrobin or Isoflucypripram on soybean growth
From the table, the compound of Cyclobutrifluram and trifloxystrobin and the compound of Cyclobutrifluram and isofluryprami can effectively prevent and control soybean cyst nematodes, have an obvious promoting effect on the growth of soybean plants, and the growth amount and yield of each treated soybean are increased along with the increase of the seed dressing dosage.
Example 4: field efficacy test of each nematicidal composition for preventing and controlling tomato root-knot nematodes
Test of field drug effect
Test subjects: tomato root-knot nematodes; the separation and identification of the Meloidogyne incognita is mainly southern root-knot nematode [ Meloidogyne incognita (Kofold & White) China ].
Test site: in a tomato greenhouse in Yunyang county in Jiangsu province, a test field is cultivated in a protected area, the harm of the tomato root-knot nematodes is severe all the year round, the yield is reduced to a certain extent, the cultivation conditions of all cells are uniform, and the local conventional cultivation practice is met.
Test crops and varieties: tomato (good witter).
Test agents: the dosages of the test agents and the preparations are shown in Table 8.
And (3) experimental design: the test cells are arranged in random blocks, and the area of each cell is 20m2Each treatment was repeated 4 times. When the tomatoes are transplanted, fixedly planted and revived (10 and 6 days in 2020), the pesticide is applied for 1 time, the pesticide is applied by irrigating the roots, the water is added for irrigating the roots, and the water consumption of each plant is 200 mL.
The investigation method comprises the following steps: the pesticide effect is investigated once before the tomato is pulled out (3 months and 10 days in 2021), 2 plants are taken at each point according to a 5-point sampling method, roots are dug out, disease grade is investigated, and the disease incidence, disease index and prevention and treatment effect are calculated.
The grading method of diseased plants comprises the following steps:
level 0: the root system has no insect gall;
level 1: a small amount of insect gall exists in the root system;
and 3, level: two thirds of the root system is full of small galls;
and 5, stage: the root system is full of small galls and secondary galls exist;
and 7, stage: the root system forms a fibrous root mass.
The drug effect calculation method comprises the following steps:
the test results are shown in Table 8:
TABLE 8 field efficacy test results of respective nematicidal compositions for controlling tomato root-knot nematodes
As can be seen from Table 8, the nematicidal compositions in different proportions have good control effects on the tomato root-knot nematodes, wherein the control effects on the tomato root-knot nematodes in all preparation examples are higher than 83%.
In conclusion, through indoor toxicity measurement and field efficacy tests, the nematicidal composition has a good effect of preventing and treating nematodes, is safe to target crops, has an obvious effect of preventing and treating nematodes, is superior to a single agent in the aspects of delaying the generation of drug resistance and prolonging the persistence, and can effectively reduce the production cost and the use cost.
Claims (10)
1. The nematicidal composition containing Cyclobutrifluram and application thereof are characterized by comprising an active ingredient A and an active ingredient B, wherein the active ingredient A is Cyclobutrifluram, the active ingredient B is any one of trifloxystrobin, Isoflucypram or Phocarb, and the mass ratio of the active ingredient A to the active ingredient B is 1: 36-36: 1.
2. The nematicidal composition according to claim 1, wherein the active ingredient B is trifloxystrobin, and the mass ratio of the active ingredient A to the active ingredient B is 1: 19-19: 1, preferably 1: 12-12: 1.
3. The nematicidal composition according to claim 1, wherein the active ingredient B is Isoflucypram, and the mass ratio of the active ingredient A to the active ingredient B is 1: 30-30: 1, preferably 1: 5-5: 1.
4. The nematicidal composition according to claim 1, wherein the active ingredient B is Phosphocarb, and the mass ratio of the active ingredient A to the active ingredient B is 1: 12-20: 1, preferably 1: 9-6: 1.
5. A nematicidal composition according to claim 1, wherein the total weight of active ingredient a and active ingredient B is from 0.1% to 80%, preferably from 0.1% to 60%, of the composition.
6. The nematicidal composition of claim 1, comprising, in addition to the active ingredient, agriculturally acceptable auxiliary ingredients selected from one or more of wetting agents, dispersing agents, thickening agents, disintegrating agents, emulsifying agents, antifreezing agents, antifoaming agents, preservatives, stabilizers, synergists, warning colors, film formers, carriers.
7. The nematicidal composition of claim 1, wherein the composition can be prepared into any agriculturally acceptable formulation, including any one of dusts, wettable powders, microcapsule suspensions, water dispersible granules, soluble tablets, soluble powders, dispersible oil suspensions, emulsifiable concentrates, aqueous emulsions, suspensions, suspoemulsions, soluble solutions, microemulsions, and seed treatment suspensions.
8. The nematicidal composition of claim 7, wherein the formulation is any one of granules, an aqueous emulsion, and a seed treatment suspension.
9. Use of a nematicidal composition comprising a Cyclobutrifluram and/or a formulation thereof according to any one of claims 1 to 8 for controlling plant parasitic pests.
10. The use according to claim 9, wherein said plant parasitic pest is a plant parasitic nematode; preferably, the plant parasitic nematode is any one or more of root-knot nematode (Meloidogyne), cyst nematode (Heterodera), Aphelenchina (Aphelenchina), stem nematode (Ditylenchus), root-knot nematode (Nacobbus) and root-rot nematode (Pratylenchus), pine wood nematode (Bursa Phellinus xylophilus).
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