CN114306783A - Personalized dialysis machine and using method thereof - Google Patents

Personalized dialysis machine and using method thereof Download PDF

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Publication number
CN114306783A
CN114306783A CN202011054627.7A CN202011054627A CN114306783A CN 114306783 A CN114306783 A CN 114306783A CN 202011054627 A CN202011054627 A CN 202011054627A CN 114306783 A CN114306783 A CN 114306783A
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China
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solution
dialysis machine
dialysate
dialysis
concentration
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CN202011054627.7A
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Chinese (zh)
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李波
曹慕真
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Tianjin Shenyouda Medical Equipment Technology Co ltd
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Tianjin Shenyouda Medical Equipment Technology Co ltd
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Priority to CN202011054627.7A priority Critical patent/CN114306783A/en
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Abstract

The invention provides a personalized dialysis machine and a using method thereof, wherein the personalized dialysis machine comprises a liquid preparation device, a liquid preparation device and a control device, wherein the liquid preparation device is arranged outside a dialysis machine main body and is used for forming a chemical concentrate solution with a certain concentration; the control unit is arranged in the dialysis machine main body and is used for controlling the liquid preparation device; the monitoring device is arranged on the dialysis machine main body and is used for detecting the concentration of the solution; and the dialysate mixing cavity is arranged inside the dialysis machine main body and used for mixing the solution to form dialysate. The invention effectively solves the problems that the concentration of chemical solution required by dialysate cannot be flexibly adjusted, the content cannot be accurately determined, and only one or two chemicals have conductivity sensors, so that whether the combination of tablets put into a mixing cavity and dialysis water is proper concentration cannot be completely determined.

Description

Personalized dialysis machine and using method thereof
Technical Field
The invention belongs to the technical field of medical treatment, and particularly relates to a personalized dialysis machine and a using method thereof.
Background
The hemodialysis main body is divided into a blood monitoring alarm system and a dialysate supply system. The blood circulation and monitoring alarm system comprises a blood pump, a heparin pump, arteriovenous pressure monitoring, air monitoring and the like; the dialysate supply and monitoring alarm system comprises a temperature control system, a liquid preparation system, a degassing system, an ultrafiltration monitoring part, a blood leakage monitoring part and the like. The working principle is as follows: the concentrated solution for dialysis and the dialysis water are prepared into qualified dialysate through a dialysate supply system, and solute dispersion, permeation and ultrafiltration are carried out on the qualified dialysate through a hemodialyzer and patient blood led out by a blood monitoring alarm system; the blood of the patient after the action returns to the body of the patient through the blood monitoring alarm system, and the liquid after dialysis is taken as waste liquid and is discharged by the dialysate supply system; the whole dialysis process is completed by continuous circulation.
Because the content of each chemical required by each patient is different, the concentration of the chemical solution required by the dialysate cannot be flexibly adjusted in the prior art, and therefore different proportions of the dialysate cannot be prepared for each patient. There is a need to specify the desired amount of each chemical in the form of a tablet, but for reasons of tablets, the amount cannot be determined very accurately, and there is no conductivity sensor for each chemical, and it cannot be confirmed whether the tablet put into the mixing chamber is combined with the dialysis water at an appropriate concentration.
The ion content of the dialysis concentrate is relatively constant, but the ion content of the blood varies from patient to patient, and even varies considerably from patient to patient. Registering multiple dialysis concentrates is impractical when different ion concentrations are registered for the new model according to the State drug administration product registration specifications.
Disclosure of Invention
The invention aims to provide a personalized dialysis machine and a using method thereof, which effectively solve the problems that the concentration of chemical solutions required by dialysate cannot be flexibly adjusted, the content cannot be accurately determined, only one or two chemicals have conductivity sensors, and whether the combination of tablets put into a mixing cavity and dialysis water is proper or not cannot be completely determined.
In order to solve the technical problems, the invention adopts the technical scheme that: a personalized dialysis machine comprising a fluid dispensing system, characterized in that: the liquid preparation device is arranged outside the dialysis machine main body and is used for forming a chemical concentrate solution with a certain concentration; the control unit is arranged in the dialysis machine main body and is used for controlling the liquid preparation device; the monitoring device is arranged on the dialysis machine main body and is used for detecting the concentration of the solution; and the dialysate mixing cavity is arranged inside the dialysis machine main body and used for mixing the solution to form dialysate.
Preferably, the liquid preparation device comprises a material barrel, a liquid inlet pump and a liquid suction pipe, the material barrel for mixing the chemical concentrate and the dialysis water to form the solution is arranged outside the dialysis machine main body, and one side of the material barrel is provided with a water inlet for introducing the dialysis water; the liquid inlet pump for controlling the flow rate of the solution is arranged on one side of the charging barrel; the pipette that introduces the solution into the dialysate mixing chamber is disposed at one side of the cartridge.
Preferably, the number of the material cylinders is the same as that of the chemical concentrated species; the number of the liquid inlet pump is consistent with that of the material cylinder; the number of the pipette is consistent with that of the material cylinder.
Preferably, the monitoring device comprises a conductivity sensor for detecting the concentration of the solution, and the conductivity sensor is arranged on one side of the liquid preparation device.
Preferably, the number of conductivity sensors corresponds to the number of chemical concentrate species.
Preferably, the chemical concentrate forms include powders and concentrates.
Preferably, the control unit comprises a central processing unit for controlling the liquid preparation device, and is arranged on the dialysis machine main body.
A method of using a personalized dialysis machine according to claim 1, characterized by: the solution preparation device is used for preparing the solution, the monitoring device is used for detecting the concentration of the solution, the control unit is used for controlling the speed of the solution introduced into the dialysate mixing cavity, the solution is introduced into the dialysate mixing cavity, and the solution is mixed to form the dialysate.
Preferably, the liquid preparation device comprises a material cylinder, a liquid inlet pump and a liquid suction pipe, the material cylinder for mixing the chemical concentrate with the dialysis water to form a solution with a certain concentration is arranged outside the dialysis machine main body, and one side of the material cylinder is provided with a water inlet for introducing the dialysis water; the liquid inlet pump for controlling the flow rate of the solution is arranged on one side of the charging barrel; the liquid suction pipe is arranged on the other side of the material cylinder and used for leading solution into the dialysate mixing cavity, when the dialysate mixing cavity is used, the dialysis water is led into the material cylinder and mixed with the chemical concentrate in the material cylinder to form the solution with a certain concentration, the control unit controls the pump speed of the liquid inlet pump, and the solution is led into the dialysate mixing cavity by the liquid suction pipe.
Preferably, the monitoring device comprises a conductivity sensor for detecting the concentration of the solution, the conductivity sensor is arranged at one side of the cartridge and detects the concentration of the solution when in use, and the control unit controls the speed of the liquid inlet pump and utilizes the pipette to guide the solution into the dialysate mixing chamber.
Due to the design of the material cylinder, the problems that the concentration of chemical solution required by dialysate cannot be flexibly adjusted and the content cannot be accurately determined are effectively solved; due to the design of the plurality of conductivity sensors, whether the concentration of each chemical substance meets the use standard or not can be confirmed, and the accuracy is ensured.
Drawings
FIG. 1 is a schematic structural diagram of a liquid distribution device of a personalized dialysis machine according to an embodiment of the present invention
FIG. 2 is a schematic diagram of the position of a dialysate mixing chamber of a personalized dialysis machine according to an embodiment of the present invention
In the figure:
1. liquid inlet pump 2, charging barrel 3 and conductivity sensor
4. A dialysate mixing chamber 5, a main body 6 of the dialysis machine,
Detailed Description
The invention is further illustrated by the following examples and figures:
in the description of the embodiments of the present invention, it should be understood that the terms "top," "bottom," and the like refer to orientations and positional relationships illustrated in the drawings, which are used for convenience in describing the present invention and for simplicity in description, and do not indicate or imply that the referenced devices or elements must have a particular orientation, be constructed in a particular orientation, and be operated, and thus should not be construed as limiting the present invention. In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "disposed" and "connected" are to be interpreted broadly, e.g., as a fixed connection, a detachable connection, or an integral connection; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood by those of ordinary skill in the art through specific situations.
In an embodiment of the present invention, as shown in fig. 1, a schematic structural diagram of a liquid preparation device of a personalized dialysis machine, the personalized dialysis machine includes a liquid preparation system, and is characterized in that: a liquid preparation device arranged outside the dialysis machine main body 5 for forming a chemical concentrate solution of a certain concentration; a control unit, arranged inside the dialysis machine body 5, for controlling the liquid dispensing device; a monitoring device provided on the dialysis machine main body 5 for detecting the solution concentration; and the dialysate mixing cavity is arranged inside the dialysis machine main body 5 and used for mixing the solution to form dialysate.
Specifically, the liquid preparation device comprises a material cylinder 2, a liquid inlet pump 1 and a liquid suction pipe, wherein the material cylinder 2 for mixing chemical concentrate and dialysis water to form a solution is hung outside the dialysis machine main body 5; the top of the material cylinder 2 is provided with a water inlet for introducing dialysis water; the number of the charging barrel 2 is consistent with the chemical concentrate species required by the patient, the charging barrel 2 is a detachable disposable charging barrel, and the chemical concentrate for dialysis is filled in the charging barrel 2 and is in a powder shape. The cartridge 2 contains individual doses of powdered chemical concentrate without the step of filling by medical personnel. When the dialysis machine is used for self-checking, a part of dialysis water reversely enters in, and all raw material powder is submerged, after the self-checking is finished, the solution in the material cylinder has a certain concentration, at the moment, a liquid inlet pump 1 for controlling the flow rate of the solution is arranged on the upper side of the material cylinder 2, the mixed solution in the material cylinder 2 needs to flow into a dialysate mixing chamber 4, the liquid inlet pump 1 controls the speed of the solution flowing into the dialysate mixing chamber 4, and the number of the liquid inlet pumps 1 is the same as that of the material cylinders 2; pipettes for introducing the solution into the dialysate mixing chamber 4 are connected to the bottom of the cartridge 2, and the number of the pipettes is the same as that of the cartridge 2, and the pipettes may be set to have a specific shape or size for distinguishing different chemical substances.
The monitoring device comprises conductivity sensors 3 for detecting the concentration of the solution, the number of the conductivity sensors is consistent with that of the charging barrel 2, the conductivity sensors are arranged at the connecting positions of the pipette and the charging barrel 2, whether the concentration of each solution meets the use standard or not is detected, and after the concentration is confirmed, the pipette starts to suck the solution in the charging barrel 2 to be mixed into the dialysate.
The form of the chemical concentrate comprises powder and concentrated liquid, and the amount of the chemical concentrate required can be more accurately controlled, and the requirement of a patient can be better matched.
The control unit comprises a central processing unit for controlling the liquid distribution device, is arranged in the main body of the dialysis machine, inputs each solution component parameter required by a patient to an operation screen of the dialysis machine and feeds the parameter back to the central processing unit, the concentration detected by the conductivity sensor 3 is also fed back to the central processing unit, and the central processing unit automatically calculates the pump speed of the liquid inlet pump 1 and controls the speed of the liquid inlet pump 1.
When in use, the utility model is used,
1. the dialysis machine is started firstly for self-checking, and mainly comprises the detection of reference voltage, reference resistance, electromagnetic valve action, operation conditions of all parts and the like of an electric part. An operator installs one side of a charging barrel 2 filled with corresponding chemical powder at the end of a liquid inlet pump 1 according to components required by a patient, the other side of the charging barrel is connected with a liquid suction pipe, a part of dialysis water is reversely fed into the charging barrel 2 during self-checking, all raw material powder is submerged, in this case, the contents such as pressure and the like are monitored, and after the self-checking is passed, a screen on a dialysis machine is clicked to enter a 'ready' state.
2. At this time, the operator inputs parameters of each component in the dialysate for the treatment of the patient, such as: dialysate temperature 36.5 ℃, sodium: 138mmol/L, potassium: 2.0mmol/L, calcium: 1.5mmol/L, magnesium: 0.5mmol/L, citrate: 1.0mmol/L, glacial acetate: 0.3mmol/L, bicarbonate: 35mmol/L, glucose: 5.56mmol/L (1g/L), vitamin: 1.5mg/L, amino acid: 3.5 mg/L. After the self-checking is finished, concentrated solution with sufficient concentration exists in the material cylinder 2, the conductivity sensor 3 arranged at the connecting position of the pipette and the material cylinder 2 detects the concentration of the solution at the moment, meanwhile, dialysis water is introduced through the water inlet, and the central processing unit automatically calculates the pump speed of each liquid inlet pump 1 according to the parameters input by the operator at first and the concentration of the solution detected by the conductivity sensor 3.
3. The conductivity sensor 3 monitors the concentration of the solution flowing out of the charging barrel 2 at any time, the corresponding detection value is fed back to the central processing unit, the pump speed of each liquid inlet pump 1 is calculated again until the detection value is consistent with the parameter value input by an operator, and the stability of the pump speed is kept at the moment. After each component in the dialysate is stable, a screen on the dialysis machine is clicked, and the dialysate enters a dialysis state, so that the dialysate can be used for dialysis treatment of a patient.
4. During the treatment, the operator can change the parameters of each component in the dialysis solution at any time according to the medical advice. For example, after 1 hour of dialysis, the following parameters are adjusted for sodium: 135mmol/L, potassium: 2.5mmol/L, calcium: 1.25mmol/L, magnesium: 0.375mmol/L, citrate: 0.8mmol/L, glacial acetate: 0.0mmol/L, bicarbonate: 30mmol/L, glucose: 11.11mmol/L (2g/L), vitamin: 3.0mg/L, amino acid: 7.0 mg/L.
5. After the operator revises and confirms the above parameters on the screen, the dialysis machine automatically completes the change of the concentration of the dialysis solution according to the steps 2 and 3. After the dialysis process is finished, the machine enters set procedures such as water washing, disinfection/acid washing and the like, and the dialysis is finished.
In another embodiment of the invention, the liquid preparation device comprises a cylinder 2, a liquid inlet pump 1 and a liquid suction pipe, wherein the cylinder 2 for mixing the chemical concentrate and the dialysis water to form a solution is hung outside the dialysis machine main body 5; the top of the material cylinder 2 is provided with a water inlet for introducing dialysis water; the number of the charging barrel 2 is consistent with the chemical concentrate species required by the patient, the charging barrel 2 is a detachable disposable charging barrel, and the chemical concentrate for dialysis is filled in the charging barrel 2 and is in a powder shape. The surface of the charging barrel 2 is provided with an openable window, so that medical personnel can place required chemical substances into the charging barrel, and can allocate the required amount of each substance by the medical personnel, so that the convenience is improved, the window is closed after the charging barrel is assembled, and the sealing property of the charging barrel is ensured. When the dialysis machine is used for self-checking, a part of dialysis water reversely enters, all raw material powder is submerged, after the self-checking is finished, the solution in the material cylinder has a certain concentration, at the moment, a liquid inlet pump 1 for controlling the flow rate of the solution is arranged at the bottom of the material cylinder 2, the mixed solution in the material cylinder 2 needs to flow into a dialysate mixing cavity 4, the liquid inlet pump 1 controls the speed of the solution flowing into the dialysate mixing cavity 4, and the number of the liquid inlet pumps 1 is the same as that of the material cylinders 2; leading-in solution is connected at the top of feed cylinder 2 to the pipette of dialysate mixing chamber 4, and the water inlet is other, and pipette one end stretches into in the feed cylinder 2, and the number of pipette is unanimous with the number of feed cylinder 2, and the pipette is for the chemical substance of difference respectively, and every pipette marks the color mark of different colours.
The monitoring device comprises conductivity sensors 3 for detecting the concentration of the solution, the number of the conductivity sensors is consistent with that of the charging barrel 2, the conductivity sensors are installed at any position on a pipette, whether the concentration of each solution meets the use standard or not is detected, and after the concentration is confirmed, the pipette starts to suck the solution in the charging barrel 2 to be mixed into the dialysate.
Although the embodiments of the present invention have been described in detail, the description is only for the preferred embodiments of the present invention and should not be construed as limiting the scope of the present invention. All equivalent changes and modifications made within the scope of the present invention shall fall within the scope of the present invention.

Claims (10)

1. A personalized dialysis machine comprising a fluid dispensing system, characterized in that:
the liquid preparation device is arranged outside the dialysis machine main body and is used for forming a chemical concentrate solution with a certain concentration;
the control unit is arranged in the dialysis machine main body and is used for controlling the liquid preparation device;
the monitoring device is arranged on the dialysis machine main body and is used for detecting the concentration of the solution;
and the dialysate mixing cavity is arranged inside the dialysis machine main body and used for mixing the solution to form dialysate.
2. The personalized dialysis machine of claim 1, wherein: the liquid preparation device comprises a material cylinder, a liquid inlet pump and a liquid suction pipe, the material cylinder for mixing the chemical concentrate and the dialysis water to form the solution is arranged outside the dialysis machine main body, and one side of the material cylinder is provided with a water inlet for introducing the dialysis water; the liquid inlet pump for controlling the flow rate of the solution is arranged on one side of the charging barrel; the pipette that introduces the solution into the dialysate mixing chamber is disposed at one side of the cartridge.
3. The personalized dialysis machine of claim 2, wherein: the charging barrel is a detachable barrel, and the number of the charging barrel is consistent with that of the chemical concentrated species; the number of the liquid inlet pump is consistent with that of the material cylinder; the number of the pipette is consistent with that of the material cylinder.
4. The personalized dialysis machine of claim 1, wherein: the monitoring device comprises a conductivity sensor for detecting the concentration of the solution and is arranged on one side of the liquid preparation device.
5. The personalized dialysis machine of claim 4, wherein: the number of the conductivity sensors is consistent with the number of the chemical concentrated species.
6. The personalized dialysis machine of claim 1, wherein: the chemical concentrate forms include powders and concentrates.
7. The personalized dialysis machine of claim 1, wherein: the control unit comprises a central processing unit for controlling the liquid distribution device and is arranged on the dialysis machine main body.
8. A method of using a personalized dialysis machine according to claim 1, characterized by: the solution preparation device is used for preparing the solution, the monitoring device is used for detecting the concentration of the solution, the control unit is used for controlling the speed of the solution introduced into the dialysate mixing cavity, the solution is introduced into the dialysate mixing cavity, and the solution is mixed to form the dialysate.
9. The method of claim 8, wherein the personalized dialysis machine comprises: the liquid preparation device comprises a material barrel, a liquid inlet pump and a liquid suction pipe, the material barrel for mixing chemical concentrate with dialysis water to form a solution with a certain concentration is arranged outside the dialysis machine main body, and one side of the material barrel is provided with a water inlet for introducing the dialysis water; the liquid inlet pump for controlling the flow rate of the solution is arranged on one side of the charging barrel; the liquid suction pipe is arranged on one side of the material cylinder and used for leading solution into the dialysate mixing cavity, when the liquid suction pipe is used, the dialysis water is led into the material cylinder and mixed with the chemical concentrate in the material cylinder to form the solution with a certain concentration, the control unit controls the pump speed of the liquid inlet pump, and the solution is led into the dialysate mixing cavity by the liquid suction pipe.
10. The method of claim 9, wherein the personalized dialysis machine comprises: the monitoring device comprises a conductivity sensor for detecting the concentration of the solution, the conductivity sensor is arranged on one side of the material barrel, when the monitoring device is used, the conductivity sensor detects the concentration of the solution, the control unit controls the pump speed of the liquid inlet pump, and the solution is guided into the dialysate mixing cavity by using the pipette.
CN202011054627.7A 2020-09-30 2020-09-30 Personalized dialysis machine and using method thereof Pending CN114306783A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202011054627.7A CN114306783A (en) 2020-09-30 2020-09-30 Personalized dialysis machine and using method thereof

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Application Number Priority Date Filing Date Title
CN202011054627.7A CN114306783A (en) 2020-09-30 2020-09-30 Personalized dialysis machine and using method thereof

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Publication Number Publication Date
CN114306783A true CN114306783A (en) 2022-04-12

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CN202011054627.7A Pending CN114306783A (en) 2020-09-30 2020-09-30 Personalized dialysis machine and using method thereof

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130008854A1 (en) * 2009-06-15 2013-01-10 Quanta Fluid Solutions Ltd Dialysis machine calibration
CN103394139A (en) * 2011-12-29 2013-11-20 富田制药株式会社 Preparation apparatus and preparation method for dialysis fluid of variable bicarbonate ion concentration type, dialysate, and dialysis system
CN105013031A (en) * 2015-07-03 2015-11-04 广州市红十字会医院 Fully automatic carbonate peritoneal dialysis device and dialysis method
EP3100749A1 (en) * 2015-06-05 2016-12-07 D_MED Consulting AG Haemodialysis device

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130008854A1 (en) * 2009-06-15 2013-01-10 Quanta Fluid Solutions Ltd Dialysis machine calibration
CN103394139A (en) * 2011-12-29 2013-11-20 富田制药株式会社 Preparation apparatus and preparation method for dialysis fluid of variable bicarbonate ion concentration type, dialysate, and dialysis system
EP3100749A1 (en) * 2015-06-05 2016-12-07 D_MED Consulting AG Haemodialysis device
CN105013031A (en) * 2015-07-03 2015-11-04 广州市红十字会医院 Fully automatic carbonate peritoneal dialysis device and dialysis method

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