CN114306413A - Preparation method and equipment of kulecuo eczema cream - Google Patents
Preparation method and equipment of kulecuo eczema cream Download PDFInfo
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- CN114306413A CN114306413A CN202210040231.XA CN202210040231A CN114306413A CN 114306413 A CN114306413 A CN 114306413A CN 202210040231 A CN202210040231 A CN 202210040231A CN 114306413 A CN114306413 A CN 114306413A
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Abstract
A preparation method and equipment of Kulecuo eczema cream comprise the following components and steps, 1-200 parts of Kulecuo extract, 1-1000 parts of emulsifier, 1-1000 parts of humectant, 1-1000 parts of matrix and 1-10000 parts of water by weight; selecting proper parts by weight of the kulekuru extract, putting the kulekuru extract into a container of preparation equipment, adding water, and heating to raise the temperature; selecting a proper weight part of matrix, an emulsifier and a humectant, putting the mixture into a container of the preparation equipment in the step, and uniformly stirring the mixture by using the preparation equipment; after stirring, cooling to room temperature, and regulating the expression of skin inflammatory factors, inhibiting inflammation and keeping skin stable by the composition of the luteolin in the fruit of the kulekuwa, the emulsifier, the humectant, the matrix and the water.
Description
Technical Field
The invention relates to the field of eczema cream formulas and preparation methods, in particular to a preparation method and equipment of a kulecuo eczema cream.
Background
Eczema is the most common skin disorder. Eczema is mainly manifested by dry skin, affected skin barrier function and sensitivity to allergens in food and the environment. Three typical stages of eczema development are: infants, children and adults. Acute inflammation accompanied by effusion on the face and limbs is common in infants. With age, eczema is more manifested by lichenification of the skin and dry molting of various body parts.
Eczema is traditionally treated by avoiding irritation and by using moisturizers. Hormonal therapy is currently the most effective way to treat eczema, but is only used for a short period of time, otherwise hormone-dependent dermatitis is even more likely to occur. Other treatment methods also comprise phototherapy, antihistamine, antibacterial and systemic immunity, but the effectiveness is to be tested and the method is not universal.
Disclosure of Invention
In view of the above, the present invention provides a method and an apparatus for preparing an eczema kulecuo cream, so as to solve the problems in the background art.
Based on the purpose, the invention provides a preparation method of the eczema kulecao paste, which comprises the following steps:
step S1, selecting 1-200 parts by weight of Kulecuo extract, putting into a container of preparation equipment, adding 1-10000 parts by weight of water, and heating to raise the temperature;
step S2, selecting 1-1000 parts by weight of matrix, 1-1000 parts by weight of emulsifier and 1-1000 parts by weight of humectant, putting into a container of the preparation equipment in the step, and uniformly stirring by using the preparation equipment;
and step S3, cooling to room temperature after stirring.
Preferably, 50 parts by weight of the kulecao extract is selected in the step S1, 1600 parts by weight of water is added, and 300 parts by weight of the matrix, 200 parts by weight of the emulsifier and 400 parts by weight of the humectant are selected in the step S2.
Preferably, 100 parts by weight of the kulecao extract is selected in the step S1, 3500 parts by weight of water is added, and 500 parts by weight of the matrix, 600 parts by weight of the emulsifier and 600 parts by weight of the humectant are selected in the step S2.
Preferably, 200 parts by weight of the kulecao extract is selected in the step S1, 7200 parts by weight of water is added, and 800 parts by weight of the matrix, 900 parts by weight of the emulsifier and 500 parts by weight of the humectant are selected in the step S2.
Preferably, after water is added into the container of the preparation device in the step S1, the temperature is raised to 25 to 100 ℃.
The extraction method of the kukola extract comprises the following steps:
s1, drying the Kulele fruit;
s2, putting the dried kuleqian into 100% ethanol solution; and
s3, filtering to obtain the kulekuwa extract.
The utility model provides a preparation equipment of fruit of chinese holly eczema cream, includes outer box, interior box, motor, (mixing) shaft, stirring leaf and supplementary rabbling mechanism, outer box side is equipped with outer chamber door, interior box side is equipped with interior chamber door, the inside heater that is provided with of interior box, and interior box pass through pulley sliding connection at the interior bottom of outer box, the motor sets up the top of box outside, the (mixing) shaft rotates the interior top of connection at outer box, and rotates by motor drive, the stirring leaf sets up on the annular side of (mixing) shaft, and inside the stirring leaf is located interior box, supplementary rabbling mechanism is used for promoting interior box inside reciprocating sliding of outer box.
More preferably, the auxiliary stirring mechanism comprises a driving machine, a first connecting rod, a second connecting rod, a first slide rail, a first slide block, a second slide rail, a second slide block and a push rod, a driving chamber is arranged on the side surface of the outer box body, the driving machine is arranged in the driving chamber, one end of the first connecting rod is fixedly connected with the output end of the driving machine, one end of the second connecting rod is rotatably connected with the other end of the first connecting rod, the first slide rail is arranged in the driving chamber, the first slide block is connected inside the first slide rail in a sliding way, the second slide rail is fixedly connected with the first slide block, the second slide block is connected in the second slide rail in a sliding way, the other end of the second connecting rod is connected on the second slide block in a rotating way, one end of the push rod is fixedly connected with the first slide rail, and the other end of the push rod penetrates through the contact surfaces of the driving chamber and the outer box body and is fixedly connected with the inner box body.
More preferably, the contact surface between the outer box and the driving chamber is provided with an opening for the push rod to reciprocate.
More preferably, the driving chamber is internally provided with a bar-shaped limiting groove for the second slide rail to slide in a reciprocating manner
The invention has the beneficial effects that: according to the invention, through the Kuletuo extract, the emulsifier, the humectant, the matrix and the water, the composition of the gamboge and the biflavone components in the Kuletuo fruit can regulate the expression of skin inflammation factors, inhibit inflammation and keep the skin stable; according to the auxiliary stirring mechanism, the auxiliary stirring mechanism comprises the outer box body, the inner box body, the motor, the stirring shaft, the stirring blade, the driving machine, the first connecting rod, the second connecting rod, the first sliding rail, the first sliding block, the second sliding rail, the second sliding block and the push rod, and when the eczema cream is prepared and raw materials are stirred, the auxiliary stirring mechanism drives the equipment to shake, so that the stirring dead angle is eliminated, the stirring efficiency is improved, and the stirring effect is improved.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
FIG. 1 is a block diagram of the process for preparing the eczema ointment of the present invention;
FIG. 2 is a schematic structural diagram of an apparatus for preparing eczema cream according to the present invention;
fig. 3 is a schematic structural view of the auxiliary stirring mechanism in fig. 2.
In the reference symbols: 1. an outer case; 2. an inner box body; 3. an electric motor; 4. a stirring shaft; 5. a drive chamber; 6. an auxiliary stirring mechanism; 7. stirring blades; 8. a pulley; 61. a driver; 62. a first link; 63. a first slide rail; 64. a first slider; 65. a push rod; 66. a second slide rail; 67. a second slider; 68. a second link.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in further detail below with reference to specific embodiments and the accompanying drawings.
It is to be noted that technical terms or scientific terms used in the embodiments of the present invention should have the ordinary meanings as understood by those having ordinary skill in the art to which the present disclosure belongs, unless otherwise defined. The use of "first," "second," and similar terms in this disclosure is not intended to indicate any order, quantity, or importance, but rather is used to distinguish one element from another. The word "comprising" or "comprises", and the like, means that the element or item listed before the word covers the element or item listed after the word and its equivalents, but does not exclude other elements or items. The terms "connected" or "coupled" and the like are not restricted to physical or mechanical connections, but may include electrical connections, whether direct or indirect. "upper", "lower", "left", "right", and the like are used merely to indicate relative positional relationships, and when the absolute position of the object being described is changed, the relative positional relationships may also be changed accordingly.
Examples
Referring to fig. 1-3, a method for preparing eczema kungle paste includes the following steps:
step S1, selecting 1-200 parts by weight of Kulecuo extract, putting into a container of preparation equipment, adding 1-10000 parts by weight of water, and heating to raise the temperature;
step S2, selecting 1-1000 parts by weight of matrix, 1-1000 parts by weight of emulsifier and 1-1000 parts by weight of humectant, putting into a container of the preparation equipment in the step, and uniformly stirring by using the preparation equipment;
and step S3, cooling to room temperature after stirring.
As a modification of the scheme, 50 parts by weight of the kulekura extract is selected in the step S1, 1600 parts by weight of water is added, and 300 parts by weight of the matrix, 200 parts by weight of the emulsifier and 400 parts by weight of the humectant are selected in the step S2.
As a modification of the scheme, 100 parts by weight of the kulecao extract is selected in the step S1, 3500 parts by weight of water is added, and 500 parts by weight of the matrix, 600 parts by weight of the emulsifier and 600 parts by weight of the humectant are selected in the step S2.
As a modification of the scheme, 200 parts by weight of the kulecao extract is selected in the step S1, 7200 parts by weight of water is added, and 800 parts by weight of the matrix, 900 parts by weight of the emulsifier and 500 parts by weight of the humectant are selected in the step S2.
As a modification of the above, in step S1, after water is added to the interior of the container of the manufacturing apparatus, the temperature is raised to 25-100 ℃.
The extraction method of the kukola extract comprises the following steps:
s1, drying the Kulele fruit;
s2, putting the dried kuleqian into 100% ethanol solution; and
s3, filtering to obtain the kulekuwa extract.
The utility model provides a preparation equipment of fruit of chinese holly eczema cream, includes outer box 1, interior box 2, motor 3, (mixing) shaft 4, stirring leaf 7 and supplementary rabbling mechanism 6, outer box 1 side is equipped with outer chamber door, 2 sides of interior box are equipped with interior chamber door, and interior box 2 passes through 8 sliding connection of pulley at the interior bottom of outer box 1, the inside heater that is provided with of interior box 2, motor 3 sets up the top at outer box 1, stirring shaft 4 rotates to be connected at the interior top of outer box 1, and is rotated by the drive of motor 3, stirring leaf 7 sets up on the annular side of (mixing) shaft 4, and inside stirring leaf 7 is located interior box 2, supplementary rabbling mechanism 6 is used for promoting interior box 2 at the inside reciprocating sliding of outer box 1.
As a modification of the above, the auxiliary stirring mechanism 6 includes a driving machine 61, a first link 62, a second link 68, a first slide rail 63, a first slider 64, a second slide rail 66, a second slider 67, and a push rod 65, the side surface of the outer box 1 is provided with a driving chamber 5, the driving machine 61 is disposed in the driving chamber 5, one end of the first link 62 is fixedly connected to the output end of the driving machine 61, one end of the second link 68 is rotatably connected to the other end of the first link 62, the first slide rail 63 is disposed in the driving chamber 5, the first slider 64 is slidably connected to the inside of the first slide rail 63, the second slide rail 66 is fixedly connected to the first slider 64, the second slider 67 is slidably connected to the inside of the second slide rail 66, the other end of the second link 68 is rotatably connected to the second slider 67, one end of the push rod 65 is fixedly connected to the first slide rail 63, the other end penetrates through the contact surface of the driving chamber 5 and the outer box body 1 and is fixedly connected with the inner box body 2.
As a modification of the above, an opening for reciprocating the push rod 65 is formed on the contact surface between the outer case 1 and the driving chamber 5.
As a modified solution of the above scheme, a strip-shaped limiting groove for the second slide rail 66 to slide back and forth is formed in the driving chamber 5.
The working process is as follows: drying the kurlela fruit, and extracting the kurlela fruit by using 100% ethanol to obtain a kurlela fruit extract.
Adding the kulekuwa extract and water into the inner box body 2, heating to a temperature higher than 25 ℃ and lower than 100 ℃, adding the matrix, the emulsifier and the humectant into the inner box body 2, operating the motor 3, driving the stirring shaft 4 to rotate by the rotation of the output end of the motor 3, driving the stirring blade 7 to rotate by the stirring shaft 4, and stirring the materials in the inner box body 2 by the stirring blade 7.
And meanwhile, the driving machine 61 is operated, the output end of the driving machine 61 rotates to drive the first connecting rod 62 to rotate, the first connecting rod 62 drives the second connecting rod 68 to swing, the second connecting rod 68 swings to drive the second sliding block 67 to slide in a reciprocating manner inside the second sliding rail 66, so that the first sliding block 64 is driven to slide in a reciprocating manner inside the first sliding rail 63, the second sliding rail 66 is driven to move in a reciprocating manner, the inner box body 2 is driven to slide in a reciprocating manner inside the outer box body 1 through the pulley 8 by the push rod 65, after the stirring is finished, the mixture is cooled to room temperature, and the bitter-berry eczema cream can be obtained after the mixture is taken out.
And (3) effect testing:
60 volunteer subjects (15-30 years old), 25 male subjects and 35 female subjects were selected. Of these, 5 people are mild eczema, 13 people are moderate eczema, and 42 people are severe eczema. Volunteers applied 4 times a day the eczema cream prepared according to the method of this example and re-evaluated after one month, the results were recorded as follows:
| mild eczema | Moderate eczema | Severe eczema | Sum of | |
| |
2 | 5 | 18 | 25 |
| Female with a view to preventing the formation of |
3 | 8 | 24 | 35 |
| Total number of |
5 | 13 | 42 | 60 |
| Percentage of severity | 8.3％ | 21.7％ | 70.0％ | 100％ |
| Disappearance of eczema after one |
5 | 12 | 35 | 52 |
| Effective rate of one month use | 100％ | 92.3％ | 83.3％ | 86.7％ |
| Side effects | 0 | 0 | 0 | 0 |
The results show that after one month of use of the eczema ointment prepared by the method of the embodiment, the symptoms of eczema are obviously improved, mild eczema patients are completely recovered, 92.3% of moderate eczema patients and 83.3% of severe eczema patients are completely recovered, the overall effective rate is 86.7%, and no anaphylactic reaction is observed in the use process.
In the previous description, numerous specific details were set forth in order to provide a thorough understanding of the present invention. The foregoing description is only a preferred embodiment of the invention, which can be embodied in many different forms than described herein, and therefore the invention is not limited to the specific embodiments disclosed above. And that those skilled in the art may, using the methods and techniques disclosed above, make numerous possible variations and modifications to the disclosed embodiments, or modify equivalents thereof, without departing from the scope of the claimed embodiments. Any simple modification, equivalent change and modification of the above embodiments according to the technical essence of the present invention are within the scope of the technical solution of the present invention.
Claims (10)
1. The preparation method of the kuleguo eczema cream is characterized by comprising the following steps:
step S1, selecting 1-200 parts by weight of Kulecuo extract, putting into a container of preparation equipment, adding 1-10000 parts by weight of water, and heating to raise the temperature;
step S2, selecting 1-1000 parts by weight of matrix, 1-1000 parts by weight of emulsifier and 1-1000 parts by weight of humectant, putting into a container of the preparation equipment in the step, and uniformly stirring by using the preparation equipment;
and step S3, cooling to room temperature after stirring.
2. The method for preparing an eczema kulecao paste according to claim 1, wherein 50 parts by weight of kulecao extract is selected and 1600 parts by weight of water is added in step S1, and 300 parts by weight of matrix, 200 parts by weight of emulsifier and 400 parts by weight of humectant are selected in step S2.
3. The method for preparing an eczema kulecao paste according to claim 1, wherein 100 parts by weight of kulecao extract is selected and 3500 parts by weight of water is added in step S1, and 500 parts by weight of matrix, 600 parts by weight of emulsifier and 600 parts by weight of humectant are selected in step S2.
4. The method for preparing an eczema kulecao paste according to claim 1, wherein 200 parts by weight of kulecao extract is selected and 7200 parts by weight of water is added in step S1, and 800 parts by weight of matrix, 900 parts by weight of emulsifier and 500 parts by weight of humectant are selected in step S2.
5. The method of claim 1, wherein the container of the manufacturing apparatus of step S1 is heated to 25-100 ℃ after water is added.
6. The method for preparing the kuleruo eczema cream as claimed in claim 1, wherein the extraction method of the kuleruo extract comprises the following steps:
s1, drying the Kulele fruit;
s2, putting the dried kuleqian into 100% ethanol solution; and
s3, filtering to obtain the kulekuwa extract.
7. A preparation equipment of Ku le Guo eczema cream is characterized by comprising:
the refrigerator comprises an outer box body (1), wherein an outer box door is arranged on the side surface of the outer box body (1);
the refrigerator comprises an inner box body (2), wherein an inner box door is arranged on the side surface of the inner box body (2), the inner box body (2) is connected to the inner bottom of the outer box body (1) in a sliding mode through a pulley (8), and a heater is arranged inside the inner box body (2);
the motor (3), the said motor (3) is set up in the top of the outer container body (1);
the stirring shaft (4) is rotatably connected to the inner top of the outer box body (1) and is driven to rotate by the motor (3);
the stirring blade (7) is arranged on the annular side surface of the stirring shaft (4), and the stirring blade (7) is positioned in the inner box body (2); and
and the auxiliary stirring mechanism (6) is used for pushing the inner box body (2) to slide in the outer box body (1) in a reciprocating manner.
8. The apparatus for preparing eczema kulecao paste according to claim 7, wherein the auxiliary stirring mechanism (6) comprises:
a driving machine (61), wherein a driving chamber (5) is arranged on the side surface of the outer box body (1), and the driving machine (61) is arranged in the driving chamber (5);
one end of the first connecting rod (62) is fixedly connected with the output end of the driving machine (61);
one end of the second connecting rod (68) is rotatably connected with the other end of the first connecting rod (62);
a first slide rail (63), said first slide rail (63) being arranged inside the drive chamber (5);
the first sliding block (64), the first sliding block (64) is connected inside the first sliding rail (63) in a sliding manner;
the second sliding rail (66), the said second sliding rail (66) is fixedly connected with first slide block (64);
the second sliding block (67) is connected inside the second sliding rail (66) in a sliding mode, and the other end of the second connecting rod (68) is connected to the second sliding block (67) in a rotating mode; and
and one end of the push rod (65) is fixedly connected with the first slide rail (63), and the other end of the push rod (65) penetrates through the contact surface of the driving chamber (5) and the outer box body (1) and is fixedly connected with the inner box body (2).
9. The apparatus for preparing kulecuo eczema cream according to claim 8, wherein the contact surface of the outer case (1) and the driving chamber (5) is provided with an opening for the reciprocating movement of the push rod (65).
10. The device for preparing the eczema kulecao paste according to claim 8, wherein a strip-shaped limiting groove for the second slide rail (66) to slide back and forth is formed in the driving chamber (5).
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210040231.XA CN114306413A (en) | 2022-01-14 | 2022-01-14 | Preparation method and equipment of kulecuo eczema cream |
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| CN202210040231.XA CN114306413A (en) | 2022-01-14 | 2022-01-14 | Preparation method and equipment of kulecuo eczema cream |
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| CN114306413A true CN114306413A (en) | 2022-04-12 |
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| CN202210040231.XA Withdrawn CN114306413A (en) | 2022-01-14 | 2022-01-14 | Preparation method and equipment of kulecuo eczema cream |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111920799A (en) * | 2020-08-14 | 2020-11-13 | 唐山克里福蒂生物科技有限公司 | Kulecuo effective component composition and preparation method and application thereof |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111920799A (en) * | 2020-08-14 | 2020-11-13 | 唐山克里福蒂生物科技有限公司 | Kulecuo effective component composition and preparation method and application thereof |
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Application publication date: 20220412 |