CN114217060A - Virus detection device for improving detection safety - Google Patents

Virus detection device for improving detection safety Download PDF

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Publication number
CN114217060A
CN114217060A CN202111459462.6A CN202111459462A CN114217060A CN 114217060 A CN114217060 A CN 114217060A CN 202111459462 A CN202111459462 A CN 202111459462A CN 114217060 A CN114217060 A CN 114217060A
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detection
groove
virus
box
driving
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CN114217060B (en
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马力敏
曾文涛
路明
范珈豪
覃炎兰
汪洋
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Shenzhen Zijian Biotech Co ltd
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Shenzhen Zijian Biotech Co ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/18Liquid substances or solutions comprising solids or dissolved gases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/26Accessories or devices or components used for biocidal treatment
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302Apparatus specially adapted for immunological test procedures
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178Special arrangements of analysers
    • G01N2035/00277Special precautions to avoid contamination (e.g. enclosures, glove- boxes, sealed sample carriers, disposal of contaminated material)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178Special arrangements of analysers
    • G01N2035/00306Housings, cabinets, control panels (details)
    • G01N2035/00316Detecting door closure
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Abstract

The application relates to a virus detection device for improving detection safety, which comprises a detection box and a reagent tube for storing virus reagents, wherein a sealing cover is arranged on the reagent tube, a detection table is arranged in the detection box in a sliding manner, a clamping mechanism for fixing the reagent tube is arranged on the detection table, a first driving piece for driving the detection table to slide is arranged in the detection box, a box inlet for sliding the detection table out is formed in the detection box, and a sealing plate for sealing the box inlet is arranged on the detection box; the detection box is internally provided with a cover opening component for opening or closing a sealing cover on the reagent tube and a detection component for detecting the virus reagent. The application has the effect of high safety in virus detection.

Description

Virus detection device for improving detection safety
Technical Field
The present application relates to the field of detection equipment, and in particular, to a virus detection device for improving detection safety.
Background
The virus is a non-cell life form and is composed of a nucleic acid long chain and a protein shell, and the virus has no own metabolic mechanism and no enzyme system; therefore, the virus leaves the host cell and becomes a chemical substance which does not have any life activity and can not independently propagate by itself; its ability to replicate, transcribe, and translate is performed in the host cell, and when it enters the host cell, it can use the materials and energy in the cell to perform life activities, generating a new generation of virus as it does according to the genetic information contained in its own nucleic acid.
Currently, in the detection of viruses, an immune labeling technique, that is, a labeled antibody such as fluorescein, radionuclide, peroxidase, or the like, is generally used, and an antigen in a specimen is detected by microscopic observation, thereby performing early diagnosis of viral infection.
The related art described above has the following drawbacks: viruses usually have strong mobility and adhesiveness, when a virus reagent is detected, part of viruses easily flow through air and are attached to clothes of detection personnel or directly enter the detection personnel through a respiratory tract, and great potential safety hazards are caused to the detection personnel.
Disclosure of Invention
The present application provides a virus detection device for improving detection safety for safety in virus detection.
The application provides a virus detection device for improving detection security adopts following technical scheme:
a virus detection device for improving detection safety comprises a detection box and a reagent tube for storing virus reagents, wherein a sealing cover is arranged on the reagent tube, a detection table is arranged in the detection box in a sliding manner, a clamping mechanism for fixing the reagent tube is arranged on the detection table, a first driving piece for driving the detection table to slide is arranged in the detection box, a box inlet for the detection table to slide out is formed in the detection box, and a sealing plate for sealing the box inlet is arranged on the detection box; the detection box is internally provided with a cover opening component for opening or closing a sealing cover on the reagent tube and a detection component for detecting the virus reagent.
By adopting the technical scheme, the extracted virus reagent is stored in the reagent tube and is sealed by the sealing cover; when viruses are detected, a reagent tube filled with the viruses is placed on a detection table and is fixed through a clamping mechanism, then the detection table is driven to slide through a first driving piece and enters a detection box, and a box inlet of the detection box is sealed through a sealing plate; the sealing cover on the reagent tube is opened through the cover opening assembly, and the virus is detected through the detection assembly; in the detection process, viruses are not easy to flow along with air, and are attached to clothes of detection personnel or directly enter the detection personnel through a respiratory tract, and the safety of the viruses in the detection process is high.
Optionally, a placing groove for placing the reagent tube is formed in the detection table, the clamping mechanism comprises two clamping blocks and a driving assembly, the two clamping blocks are arranged, two accommodating grooves communicated with the placing groove are formed in the side wall of the placing groove, the two clamping blocks are respectively arranged in the two accommodating grooves in a sliding mode, and the driving assembly is used for driving the two clamping blocks to be close to or away from each other.
Through adopting above-mentioned technical scheme, place reagent pipe in the standing groove of examining test table, order about two clamp splices through drive assembly and be close to each other or keep away from to the realization is fixed to the clamp of reagent pipe.
Optionally, the two clamping blocks are provided with anti-slip pads at the ends close to each other, and the anti-slip pads are made of elastic materials.
Through adopting above-mentioned technical scheme, two clamp splices are pressing from both sides the fastening timing to the reagent pipe, contact through slipmat and reagent pipe, increase the stability when pressing from both sides tight to actual pipe to, because the slipmat adopts elastic material, can also prevent to a certain extent that two clamp splices from making the reagent pipe break because of the clamp force is too big.
Optionally, the driving assembly comprises an adjusting screw and a transmission part, the accommodating groove is internally provided with the adjusting screw in a rotating mode, a threaded hole is formed in one end, close to the bottom wall of the accommodating groove, of the clamping block along the sliding direction of the clamping block, the adjusting screw penetrates through the threaded hole and is in threaded connection with the clamping block, and the transmission part is used for driving the two adjusting screws to rotate simultaneously.
By adopting the technical scheme, the two adjusting screws are driven to rotate simultaneously through the transmission part, and the two adjusting screws are in threaded connection with the clamping blocks and respectively drive the two clamping blocks to slide in the accommodating grooves when rotating, so that the two clamping blocks are driven to approach or move away from each other; and, when adjusting screw stopped rotating, can carry out spacingly to the fixture block, place the chain fixture block to a certain extent and relax.
Optionally, the driving medium includes the rack, two the first connecting groove has been seted up along the slip direction of perpendicular clamp splice to the lateral wall of storage tank, it is provided with all to slide in the first connecting groove the rack, two equal coaxial fixed gear that is provided with on the adjusting screw, just rack and gear engagement, the second connecting groove that communicates with the standing groove is seted up along the slip direction of rack to the lateral wall of first connecting groove, it is provided with the briquetting, two to slide along the slip direction of rack in the standing groove the rack and briquetting fixed connection, be provided with in the standing groove and be used for ordering about the gliding first top of briquetting and push away the piece.
By adopting the technical scheme, when the reagent tube is placed in the placing groove, the bottom end of the reagent tube is abutted against the surface of the pressing block, the reagent tube is continuously pressed downwards, the reagent tube pushes the pressing block to slide towards the direction close to the bottom wall of the placing groove and drives the two racks to respectively slide in the first connecting groove, and the racks slide and drive the gear to rotate due to the meshing of the racks and the gear, so that the two adjusting screw rods are respectively driven to rotate through the two racks, the two clamping blocks are mutually close to each other, the clamping of the reagent tube is realized, and the fastening and the timing of the reagent tube clamp are more convenient and faster; when reagent pipe was taken off to needs, ordered about the briquetting through first top pushing part and kept away from the standing groove diapire, drove two adjusting screw rod antiport to make two clamp splices keep away from each other, can take off reagent pipe.
Optionally, the first pushing member includes a spring, the spring is disposed in the placement groove, one end of the spring abuts against the bottom wall of the placement groove, the other end of the spring abuts against the pressing block, and a limiting member for limiting the sliding of the pressing block is disposed in the placement groove.
By adopting the technical scheme, when the reagent tube is placed in the placing groove and the pressing block is pushed to slide towards the direction close to the bottom wall of the placing groove, the spring is pressed, and after the two clamping blocks clamp and fix the reagent tube, the sliding of the pressing block is limited by the limiting part; when reagent pipe is taken off to needs, only need through loosening the locating part, the briquetting slides to keeping away from standing groove diapire direction under the spring action of spring to make two clamp splices keep away from each other, can take off reagent pipe.
Optionally, the locating part includes the stopper, the spacing groove has been seted up along the slip direction of perpendicular briquetting to the lateral wall of briquetting, the stopper slides and sets up at the spacing inslot, the spacing inslot is provided with and is used for ordering about the stopper to keeping away from the gliding elastic component of spacing groove diapire direction, the lateral wall of standing groove is seted up and is used for supplying stopper male draw-in groove, it is used for pushing away the second of the ejecting draw-in groove of stopper to be provided with on the test table to push away the piece.
By adopting the technical scheme, the limiting blocks are always positioned in the limiting grooves in the process that the pressing blocks slide towards the direction close to the bottom wall of the placing groove, when the two clamping blocks clamp the reagent tube, the limiting blocks are opposite to the clamping grooves, and the limiting blocks are inserted into the clamping grooves through the elastic action of the elastic pieces, so that the limiting of the pressing blocks is realized; when the reagent tube needs to be taken down, the limiting block is ejected out of the clamping groove through the second ejecting piece, and the pressing block can slide in the placing groove.
Optionally, the subassembly of uncapping includes adapter sleeve, second driving piece and third driving piece, the direction slip along parallel detection case diapire in the detection case is provided with the mounting panel, the second driving piece is used for ordering about the mounting panel and slides, the adapter sleeve slides along the direction of perpendicular mounting panel and sets up on the mounting panel, the third driving piece sets up on the mounting panel, just the third driving piece is used for ordering about the adapter sleeve and slides, the fixed grafting piece that is provided with on the adapter sleeve, the sealed lid lock joint is on the reagent pipe, offer on the sealed lid and be used for supplying grafting piece male inserting groove.
Through adopting above-mentioned technical scheme, reagent pipe is after getting into the detection case, orders about the mounting panel case through the second driving piece and is close to the reagent pipe direction and slides to make the grafting piece on the adapter sleeve insert the inserting groove on the sealed lid, later, orders about the adapter sleeve through the third driving piece and slides on, can make sealed lid and reagent pipe break away from, and rethread second driving piece orders about the mounting panel and keeps away from the reagent pipe, can detect the viral reagent in the reagent pipe.
Optionally, the detection assembly comprises an injector and a microscope, the injector is fixedly arranged on the detection box, the injector is internally used for storing reaction reagents, the injector is communicated with an injection needle, the injection needle is fixedly arranged in the detection box, and the microscope is fixedly arranged on the top wall of the detection box.
By adopting the technical scheme, the reagent tube is firstly slid to the position right opposite to the injection needle, the reaction reagent is injected into the reagent tube through the liquid guide tube and the injection needle by the injector, and then the reagent tube is slid to the observation position of the microscope, so that the virus can be detected.
Optionally, a liquid storage tank is fixedly arranged on the detection box, disinfectant is stored in the liquid storage tank, a spray head is communicated with the liquid storage tank, the spray head extends into the detection box, and a water pump for conveying the disinfectant to the spray head is arranged on the liquid storage tank.
Through adopting above-mentioned technical scheme, virus detection accomplishes the back, carries the shower nozzle through the antiseptic solution of water pump in with the liquid storage tank to spray the antiseptic solution in the detection case, disinfect to the surface of detection incasement portion and reagent pipe and test table, further improve the security.
In summary, the present application includes at least one of the following beneficial technical effects:
1. when viruses are detected, a reagent tube filled with the viruses is placed on a detection table and is fixed through a clamping mechanism, then the detection table is driven to slide through a first driving piece and enters a detection box, and a box inlet of the detection box is sealed through a sealing plate; the sealing cover on the reagent tube is opened through the cover opening assembly, and the virus is detected through the detection assembly; in the detection process, the virus is not easy to flow along with the air and is attached to the clothes of a detector or directly enters the body of the detector through a respiratory tract, so that the safety of the virus detection is high;
2. when the reagent tube is placed into the placing groove, the bottom end of the reagent tube is abutted against the surface of the pressing block, the reagent tube is continuously pressed downwards, the reagent tube pushes the pressing block to slide towards the direction close to the bottom wall of the placing groove and drives the two racks to respectively slide in the first connecting groove, and the racks slide and drive the gear to rotate due to the meshing of the racks and the gear, so that the two adjusting screw rods are respectively driven to rotate through the two racks, the two clamping blocks are mutually close, the reagent tube is clamped, and the reagent tube clamp is more conveniently and quickly fastened;
3. after virus detection accomplished, carry the shower nozzle through the antiseptic solution of water pump in with the liquid storage tank to spray the antiseptic solution in the detection case, disinfect the surface of detection incasement portion and reagent pipe and test table, further improve the security.
Drawings
FIG. 1 is a schematic diagram of the overall structure of an embodiment of the present application;
FIG. 2 is a sectional view of the structure of the embodiment of the present application, which is mainly used for expressing the installation relationship between the sealing plate and the detection box, and the specific structure of the cover opening assembly and the detection assembly;
FIG. 3 is an enlarged view of portion A of FIG. 2;
FIG. 4 is an enlarged view of portion B of FIG. 2;
FIG. 5 is a sectional view of the structure of the embodiment of the present application, which is mainly used for showing the installation relationship between the liquid storage tank and the detection box, and the internal structure of the detection platform;
FIG. 6 is an enlarged view of portion C of FIG. 5;
FIG. 7 is a sectional view of a part of the structure of the embodiment of the present application, which is mainly used for expressing the internal structure of the test platform.
Description of reference numerals: 1. a detection box; 11. a first driving member; 111. a support plate; 12. a box inlet; 121. a sealing plate; 13. a sealing groove; 131. a gasket; 14. a fixing plate; 15. a guide groove; 151. a pull rod; 152. pulling a rope; 153. a first tension spring; 16. mounting a plate; 17. a liquid storage tank; 171. a water pump; 172. a water conduit; 173. a spray head; 2. a reagent tube; 21. a sealing cover; 211. a plug section; 212. a connecting section; 2121. inserting grooves; 3. a detection table; 31. a placement groove; 311. a card slot; 32. a containing groove; 33. a first connecting groove; 34. a second connecting groove; 341. a connecting rod; 35. briquetting; 351. a rubber pad; 352. a limiting groove; 353. an elastic member; 36. a spring; 37. a limiting block; 38. a top rod; 381. an anti-drop block; 382. a second tension spring; 39. a through hole; 4. a lid opening assembly; 41. connecting sleeves; 411. an insertion block; 42. a second driving member; 43. a third driving member; 5. a detection component; 51. an injector; 511. a catheter; 512. an injection needle; 52. a microscope; 6. a clamping mechanism; 61. a clamping block; 611. a non-slip mat; 62. a drive assembly; 621. adjusting the screw rod; 6211. a gear; 622. a rack.
Detailed Description
The present application is described in further detail below with reference to figures 1-7.
The embodiment of the application discloses a virus detection device for improving detection safety. Referring to fig. 1, the device comprises a detection box 1 and a reagent tube 2 for storing a virus reagent, wherein a sealing cover 21 is buckled on the reagent tube 2, an observation window is arranged on the top wall and the side wall of the detection box 1, the observation window is sealed by a glass plate, a detection table 3 is arranged in the detection box 1 in a sliding manner, a first driving piece 11 for driving the detection table 3 to slide is arranged in the detection box 1, and a placing groove 31 for placing the reagent tube 2 is arranged at the top end of the detection table 3 along the direction vertical to a support plate 111; a box inlet 12 for the detection table 3 to slide out is formed in the side wall of the detection box 1, and a sealing cover 21 for sealing the box inlet 12 is arranged on the detection box 1; the detection box 1 is internally provided with a cover opening component 4 for opening a sealing cover 21 on the reagent tube 2 and a detection component 5 for detecting virus reagent.
Referring to fig. 1, the first driving member 11 includes two first rodless cylinders, the two first rodless cylinders are parallel in degree direction, the length direction of the two first rodless cylinders is perpendicular to the side wall of the detection box 1, the box inlet 12 is formed in the side wall, a support plate 111 is welded on the piston rods of the two first rodless cylinders, and the detection table 3 is fixedly arranged on the support plate 111.
Refer to fig. 2, 3, closing plate 121 articulates the case mouth 12 department of advancing at detection case 1, the seal groove 13 with case mouth 12 intercommunication is seted up to the lateral wall of offering case mouth 12 on the detection case 1, seal groove 13 is used for supplying closing plate 121 to insert, the diapire of seal groove 13 bonds and has sealed the pad 131, sealed pad 131 adopts the rubber material, after detection platform 3 got into detection case 1, rotate closing plate 121, make closing plate 121 and sealed pad 131 support tightly, thereby seal detection case 1, make the formation confined space in the detection case 1, the security that the virus detected time measuring improves greatly.
Referring to fig. 3, a fixing plate 14 is fixedly disposed inside the detection box 1, two guide grooves 15 communicated with the sealing groove 13 are formed in the bottom wall of the sealing groove 13 along the sliding direction of the detection table 3, the two guide grooves 15 are respectively disposed on two sides of the sealing plate 121, the guide grooves 15 extend into the fixing plate 14, a pull rod 151 is slidably disposed in the guide grooves 15, a pull rope 152 is fixedly disposed on the pull rod 151, the pull rope 152 is fixedly connected with the sealing plate 121, a first tension spring 153 is disposed in the guide groove 15, one end of the first tension spring 153 is fixedly connected with the bottom wall of the guide groove 15, and the other end of the first tension spring 153 is fixedly connected with the pull rod 151.
When the detection table 3 slides out of the detection box 1, the supporting plate 111 abuts against one end, close to the interior of the detection box 1, of the sealing plate 121, the supporting plate 111 is continuously driven to slide, the supporting plate 111 pushes the sealing plate 121 to rotate, and then the sealing plate 121 can be opened; when detecting platform 3 and sliding into detection case 1, backup pad 111 loses the power of supporting tight to closing plate 121, and first extension spring 153 pulling pull rod 151 slides to being close to 15 diapire directions of guide way this moment to it is rotatory to drive closing plate 121 through stay cord 152, thereby carries out closing plate 121 to entering case mouth 12, whole process need not manual operation, has improved the convenience when using greatly.
Referring to fig. 2 and 4, the cover opening assembly 4 includes a connection sleeve 41, a second driving member 42 and a third driving member 43, the mounting plate 16 is slidably disposed in the detection box 1 along the sliding direction of the support plate 111, the second driving member 42 includes two second rodless cylinders, the two second rodless cylinders are fixedly disposed on two side walls of the detection box 1 respectively, the length direction of the second rodless cylinders is parallel to the sliding direction of the mounting plate 16, and the mounting plate 16 is welded to a piston of the second rodless cylinders.
Referring to fig. 2 and 4, the connecting sleeve 41 is slidably disposed at the bottom of the mounting plate 16 along a direction perpendicular to the mounting plate 16, the third driving member 43 includes a driving cylinder fixedly disposed on the top wall of the mounting plate 16, a piston rod of the driving cylinder penetrates through the mounting plate 16 and is fixedly connected to the connecting sleeve 41, and an insertion block 411 is fixedly disposed on the inner wall of the connecting sleeve 41; sealed lid 21 grafting section 211 and linkage segment 212, grafting section 211 and linkage segment 212 integrated into one piece, and the grafting end all adopts rubber material with linkage segment 212, and the grafting end is used for inserting in reagent pipe 2, and the lateral wall of linkage segment 212 is offered and is used for supplying grafting piece 411 male inserting groove 2121, and the lateral wall of linkage segment 212 is seted up around seting up to grafting groove 2121.
After the reagent tube 2 enters the detection box 1, the second rodless cylinder drives the mounting plate 16 to slide close to the direction of the reagent tube 2, the plug block 411 on the connecting sleeve 41 is inserted into the plug groove 2121 on the sealing cover 21, then the connecting sleeve 41 is driven to slide by driving the cylinder, the sealing cover 21 can be separated from the reagent tube 2, the mounting plate 16 is driven by the second driving piece 42 to be far away from the reagent tube 2, and then the virus reagent in the reagent tube 2 can be detected.
Referring to fig. 2 and 4, the detection assembly 5 comprises an injector 51 and a microscope 52, the injector 51 is fixedly arranged on the side wall of the detection box 1, the outlet end of the injector 51 is communicated with a liquid guide tube 511, the liquid guide tube 511 extends into the detection box 1, the liquid guide tube 511 is communicated with an injection needle 512, the reagent tube 2 slides to the position opposite to the injection needle 512, and the injector 51 is used for storing reaction reagents, such as fluorescein, radionuclide, peroxidase and the like; the microscope 52 is fixedly arranged on the top wall of the detection box 1; the reagent tube 2 is first slid to the position opposite to the injection needle 512, the reaction reagent is injected into the reagent tube 2 through the liquid guide tube 511 and the injection needle 512 by the injector 51, and then the reagent tube 2 is slid to the observation position of the microscope 52, so that the virus can be detected.
Referring to fig. 5, a liquid storage tank 17 is fixedly arranged on the side wall of the detection box 1, a water inlet is formed in the top wall of the liquid storage tank 17, an end cover is buckled at the water inlet, disinfectant is stored in the liquid storage tank 17, the disinfectant is usually alcohol, and different disinfectants can be arranged according to the characteristics of actually detected viruses in actual use; the bottom wall of the liquid storage tank 17 is provided with a water outlet, the water outlet is provided with a water pump 171, the water outlet of the liquid storage tank 17 is communicated with the water inlet end of the water pump 171, a water outlet pipe of the water pump 171 is communicated with a water guide pipe 172, the water guide pipe 172 extends into the detection box 1, one end of the water guide pipe 172, which is located at the detection box 1, is communicated with a spray head 173, and the spray head 173 is close to the top end of the detection box 1.
After virus detection accomplished, earlier through the cooperation of second rodless cylinder with drive actuating cylinder, detain sealed lid 21 back reagent pipe 2 on, the antiseptic solution in water pump 171 will store liquid 17 is carried to shower nozzle 173 to spray the antiseptic solution in detection case 1, disinfect to the inside and reagent pipe 2 of detection case 1 and the surface of detecting platform 3, further improve the security.
Referring to fig. 6, a clamping mechanism 6 for fixing the reagent tube 2 is arranged on the detection table 3, the clamping mechanism 6 includes two clamping blocks 61 and a driving assembly 62, two accommodating grooves 32 are formed in the side wall of the accommodating groove 31 along the direction parallel to the supporting plate 111, the two clamping blocks 61 are arranged, the two clamping blocks 61 are respectively arranged in the two accommodating grooves 32 in a sliding manner, the two clamping blocks 61 are symmetrically arranged along the central axis of the accommodating groove 31, and the driving assembly 62 is used for driving the two clamping blocks 61 to approach or move away from each other; the reagent tube 2 is placed in the placing groove 31 of the detection table 3, and the two clamping blocks 61 are driven to be close to or far away from each other by the driving assembly 62, so that the reagent tube 2 is clamped and fixed.
Referring to fig. 6, the anti-slip pads 611 are bonded to the ends of the two clamping blocks 61 close to each other, the anti-slip pads 611 are made of elastic materials, and in this application, the anti-slip pads 611 are made of rubber materials; in other embodiments, the non-slip pad 611 may be replaced with a sponge; when the two clamping blocks 61 clamp and fasten the reagent tube 2, the anti-slip pads 611 contact with the reagent tube 2, so that the stability of clamping the actual tube is improved, and the anti-slip pads 611 are made of elastic materials, so that the two clamping blocks 61 can be prevented from breaking the reagent tube 2 due to overlarge clamping force to a certain extent.
Referring to fig. 6, the driving assembly 62 includes two adjusting screws 621 and a transmission member, the two adjusting screws 621 are respectively located in the two accommodating grooves 32, the two adjusting screws 621 are rotatably connected to the bottom wall of the accommodating groove 32, threaded holes are respectively formed in one ends of the two clamping blocks 61 close to the bottom wall of the accommodating groove 32 along the sliding direction of the clamping blocks 61, and the two adjusting screws 621 respectively penetrate through the threaded holes of the two clamping blocks 61 and are in threaded connection with the clamping blocks 61.
Referring to fig. 6, the transmission member includes two racks 622, the side walls of the two accommodating grooves 32 are both provided with first connecting grooves 33 perpendicular to the supporting plate 111, one of the two racks 622 is slidably disposed in one of the first connecting grooves 33, the other rack 622 is slidably disposed in the other first connecting groove 33, the two adjusting screws 621 are coaxially and fixedly provided with gears 6211, and the racks 622 are engaged with the gears 6211.
Referring to fig. 6, the side walls of the two first connecting grooves 33 are both provided with second connecting grooves 34 communicated with the placing groove 31 along the sliding direction of the rack 622, connecting rods 341 are all slidably arranged in the two second connecting grooves 34, pressing blocks 35 are slidably arranged in the placing groove 31 along the sliding direction of the rack 622, two ends of each connecting rod 341 are respectively fixedly connected with the pressing blocks 35 and the rack 622, and a rubber pad 351 is bonded to one end of each pressing block 35, which is far away from the bottom wall of the placing groove 31.
When reagent pipe 2 was put into standing groove 31, reagent pipe 2's bottom and briquetting 35 surface butt, continue to push down reagent pipe 2, reagent pipe 2 promotes briquetting 35 and slides to being close to standing groove 31 diapire direction, and drive two racks 622 and slide respectively in first connecting groove 33, because rack 622 and gear 6211 mesh, rack 622 slides and drives gear 6211 and rotates, thereby drive two adjusting screw 621 through two racks 622 respectively and rotate, because adjusting screw 621 and clamp splice 61 threaded connection, when two adjusting screw 621 pivoted, drive two clamp splices 61 respectively and slide in storage tank 32, make two clamp splices 61 be close to each other, thereby press from both sides tight fixed to reagent pipe 2.
Referring to fig. 6, a first pushing member for driving the pressing block 35 to slide in a direction away from the bottom wall of the placing groove 31 is arranged in the placing groove 31, the first pushing member includes a spring 36, the spring 36 is arranged in the placing groove 31, one end of the spring 36 abuts against the bottom wall of the placing groove 31, and the other end of the spring 36 abuts against the pressing block 35; when the reagent tube 2 needs to be taken down, the pressing block 35 slides in the direction away from the bottom wall of the placing groove 31 under the elastic force of the spring 36, so that the two clamping blocks 61 are away from each other, and the reagent tube 2 can be taken down.
Referring to fig. 6 and 7, a limiting member for limiting the sliding of the pressing block 35 is arranged in the placing groove 31, the limiting member includes a limiting block 37, a limiting groove 352 is formed in the side wall of the pressing block 35 along the direction perpendicular to the sliding direction of the pressing block 35, the limiting block 37 is slidably arranged in the limiting groove 352, an elastic member 353 for driving the limiting block 37 to slide in the direction away from the bottom wall of the limiting groove 352 is arranged in the limiting groove 352, the elastic member 353 includes a pressure spring, one end of the pressure spring is abutted against the bottom wall of the limiting groove 352, the other end of the pressure spring is abutted against the limiting block 37, and a clamping groove 311 for inserting the limiting block 37 is formed in the side wall of the placing groove 31; briquetting 35 is being close to the gliding in-process of standing groove 31 diapire direction, and stopper 37 is in spacing groove 352 all the time, and when two clamp splice 61 pressed from both sides tight reagent pipe 2, stopper 37 just right with draw-in groove 311 to through the spring action of pressure spring, make stopper 37 insert draw-in groove 311, realize spacing to briquetting 35.
Referring to fig. 7, it is used for ejecting the second top push member of draw-in groove 311 with stopper 37 to detect to be provided with on the platform 3, the second top push member includes ejector pin 38, the lateral wall of detecting platform 3 has seted up the through-hole 39 that communicates with draw-in groove 311 along the direction that stopper 37 inserted draw-in groove 311, ejector pin 38 slides and sets up in through-hole 39, anticreep piece 381 has all been welded at the both ends of ejector pin 38, the cover is equipped with second extension spring 382 on ejector pin 38, second extension spring 382 is located draw-in groove 311, the one end of second extension spring 382 and the diapire fixed connection of draw-in groove 311, the other end of second extension spring 382 and the anticreep piece 381 fixed connection that is located draw-in groove 311.
The implementation principle of the virus detection device for improving the detection safety in the embodiment of the application is as follows: storing the extracted virus reagent in the reagent tube 2, and sealing by a sealing cover 21; when examining the virus, place reagent pipe 2 that is equipped with the virus in examining the standing groove 31 on the test table 3, and push down reagent pipe 2, reagent pipe 2 promotes briquetting 35 and slides to being close to standing groove 31 diapire direction, and drive two racks 622 and slide respectively in first connecting groove 33, thereby order about two adjusting screw 621 through gear 6211 and rotate, when two adjusting screw 621 pivoted, drive two clamp splice 61 respectively and slide in storage tank 32, thereby order about two clamp splice 61 and be close to each other, press from both sides tightly reagent pipe 2.
Then, starting the first rodless cylinder to drive the detection table 3 to slide, enabling the detection table 3 to enter the detection box 1 from the box inlet 12 of the detection box 1, and sealing the box inlet 12 through the sealing plate 121; after the reagent tube 2 enters the detection box 1, the second rodless cylinder drives the mounting plate 16 to slide in the direction close to the reagent tube 2, the insertion block 411 on the connecting sleeve 41 is inserted into the insertion groove 2121 on the sealing cover 21, and then the driving cylinder drives the connecting sleeve 41 to slide upwards, so that the sealing cover 21 can be separated from the reagent tube 2.
Sliding the reagent tube 2 to the position opposite to the injection needle 512, injecting the reaction reagent into the reagent tube 2 through the liquid guide tube 511 and the injection needle 512 by the injector 51, and then sliding the reagent tube 2 to the observation position of the microscope 52 for virus detection; the virus is difficult for along with the air flow at the testing process to attached to the clothing of testing personnel or directly get into the testing personnel internal through the respiratory track, the security height when the virus detects.
The above embodiments are preferred embodiments of the present application, and the protection scope of the present application is not limited by the above embodiments, so: all equivalent changes made according to the structure, shape and principle of the present application shall be covered by the protection scope of the present application.

Claims (10)

1. A virus detection apparatus for improving detection safety, characterized in that: the detection device comprises a detection box (1) and a reagent tube (2) for storing a virus reagent, wherein a sealing cover (21) is arranged on the reagent tube (2), a detection table (3) is arranged in the detection box (1) in a sliding manner, a clamping mechanism (6) for fixing the reagent tube (2) is arranged on the detection table (3), a first driving piece (11) for driving the detection table (3) to slide is arranged in the detection box (1), a box inlet (12) for the detection table (3) to slide out is formed in the detection box (1), and a sealing plate (121) for sealing the box inlet (12) is arranged on the detection box (1); the detection box (1) is internally provided with a cover opening component (4) for opening or closing a sealing cover (21) on the reagent tube (2) and a detection component (5) for detecting a virus reagent.
2. A virus detection apparatus for improving detection safety according to claim 1, wherein: the reagent tube detection device is characterized in that a placing groove (31) used for placing a reagent tube (2) is formed in the detection table (3), the clamping mechanism (6) comprises two clamping blocks (61) and a driving assembly (62), the two clamping blocks (61) are arranged, two accommodating grooves (32) communicated with the placing groove (31) are formed in the side wall of the placing groove (31), the two clamping blocks (61) are arranged in the two accommodating grooves (32) in a sliding mode respectively, and the driving assembly (62) is used for driving the two clamping blocks (61) to be close to or away from each other.
3. A virus detection apparatus for improving detection safety according to claim 2, wherein: anti-skid pads (611) are arranged at the ends, close to each other, of the two clamping blocks (61), and the anti-skid pads (611) are made of elastic materials.
4. A virus detection apparatus for improving detection safety according to claim 2, wherein: drive assembly (62) include adjusting screw (621) and driving medium, two all rotate in storage tank (32) and be provided with adjusting screw (621), the slip direction that is close to storage tank (32) diapire on clamp splice (61) sets up threaded hole along clamp splice (61), adjusting screw (621) wear to locate the screw hole and with clamp splice (61) threaded connection, the driving medium is used for ordering about two adjusting screw (621) and rotates simultaneously.
5. A virus detection apparatus for improving detection safety according to claim 4, wherein: the driving medium includes rack (622), two first connecting groove (33) have been seted up along the slip direction of perpendicular clamp splice (61) to the lateral wall of storage tank (32), it is provided with all to slide in first connecting groove (33) rack (622), two equal coaxial fixed gear (6211) that is provided with on adjusting screw (621), just rack (622) and gear (6211) meshing, second connecting groove (34) with standing groove (31) intercommunication are seted up along the slip direction of rack (622) to the lateral wall of first connecting groove (33), it is provided with briquetting (35) to slide along the slip direction of rack (622) in standing groove (31), two rack (622) and briquetting (35) fixed connection, be provided with in standing groove (31) and be used for ordering about the gliding first top push member of briquetting (35).
6. A virus detection apparatus for improving detection safety according to claim 5, wherein: the first pushing piece comprises a spring (36), the spring (36) is arranged in the placing groove (31), one end of the spring (36) is abutted to the bottom wall of the placing groove (31), the other end of the spring (36) is abutted to the pressing block (35), and a limiting piece used for limiting the sliding of the pressing block (35) is arranged in the placing groove (31).
7. The virus detection apparatus for improving detection safety according to claim 6, wherein: the locating part includes stopper (37), spacing groove (352) have been seted up along the slip direction of perpendicular briquetting (35) to the lateral wall of briquetting (35), stopper (37) slide to set up in spacing groove (352), be provided with in spacing groove (352) and be used for ordering about stopper (37) to keeping away from spacing groove (352) gliding elastic component (353) of diapire direction, lateral wall of standing groove (31) is seted up and is used for supplying stopper (37) male draw-in groove (311), it is provided with the second top push piece that is used for ejecting draw-in groove (311) with stopper (37) on detection platform (3).
8. A virus detection apparatus for improving detection safety according to claim 1, wherein: the cover opening assembly (4) comprises a connecting sleeve (41), a second driving piece (42) and a third driving piece (43), a mounting plate (16) is arranged in the detection box (1) in a sliding mode along the direction of the bottom wall of the parallel detection box (1), the second driving piece (42) is used for driving the mounting plate (16) to slide, the connecting sleeve (41) is arranged on the mounting plate (16) in a sliding mode along the direction perpendicular to the mounting plate (16), the third driving piece (43) is arranged on the mounting plate (16), the third driving piece (43) is used for driving the connecting sleeve (41) to slide, an inserting block (411) is fixedly arranged on the connecting sleeve (41), the sealing cover (21) is buckled on the reagent tube (2), and an inserting groove (2121) for inserting the inserting block (411) is formed in the sealing cover (21).
9. A virus detection apparatus for improving detection safety according to claim 1, wherein: detection subassembly (5) include syringe (51) and microscope (52), syringe (51) are fixed to be set up on detection case (1), just be used for depositing reagent in syringe (51), intercommunication has injection needle (512) on syringe (51), injection needle (512) are fixed to be provided with in detection case (1), microscope (52) are fixed to be set up the roof in detection case (1).
10. A virus detection apparatus for improving detection safety according to claim 1, wherein: the detection box is characterized in that a liquid storage tank (17) is fixedly arranged on the detection box (1), disinfectant is stored in the liquid storage tank (17), a spray head (173) is communicated with the liquid storage tank (17), the spray head (173) extends into the detection box (1), and a water pump (171) used for conveying the disinfectant to the spray head (173) is arranged on the liquid storage tank (17).
CN202111459462.6A 2021-12-02 2021-12-02 Virus detection device for improving detection safety Active CN114217060B (en)

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