CN114190370A - Ultralow temperature cell transportation and storage device for stem cell research - Google Patents
Ultralow temperature cell transportation and storage device for stem cell research Download PDFInfo
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- CN114190370A CN114190370A CN202210149378.2A CN202210149378A CN114190370A CN 114190370 A CN114190370 A CN 114190370A CN 202210149378 A CN202210149378 A CN 202210149378A CN 114190370 A CN114190370 A CN 114190370A
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0236—Mechanical aspects
- A01N1/0263—Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving, e.g. cool boxes, blood bags or "straws" for cryopreservation
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/18—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents providing specific environment for contents, e.g. temperature above or below ambient
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
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- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/24—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D85/00—Containers, packaging elements or packages, specially adapted for particular articles or materials
- B65D85/50—Containers, packaging elements or packages, specially adapted for particular articles or materials for living organisms, articles or materials sensitive to changes of environment or atmospheric conditions, e.g. land animals, birds, fish, water plants, non-aquatic plants, flower bulbs, cut flowers or foliage
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Abstract
The invention discloses an ultralow-temperature cell transportation and storage device for stem cell research, which comprises a transportation box, wherein a storage box is arranged in the transportation box, a cooling pipe is arranged above the storage box in the transportation box, a control box is arranged below the storage box, the cooling pipe is connected with a storage box pipeline, and the control box enables the storage box to be in a vertical state. The hot junction that the cooling tube extracted outside air and produced through the Peltier effect heats the air, the sterilization, the cold junction that the cooling tube produced through the Peltier effect once more cools down the hot-air, make the moisture condensation in the hot-air become the water of low temperature, make the hot-air cool down into the cold air, the cooling tube transmits the water of low temperature to the storage box in, the storage box cools down the stem cell through low-temperature water, the cooling tube infuses the box of storage box with the cold air, the cold air cools down the box, prevent that box and low temperature water from carrying out heat and cold exchange and influence the effect of cold-stored stem cell.
Description
Technical Field
The invention relates to the technical field of cell low-temperature transportation, in particular to an ultralow-temperature cell transportation and storage device for stem cell research.
Background
The stem cell has the potential functions of regenerating various tissues and organs and human bodies, is an insufficiently differentiated and immature cell, and has the name of a universal cell in the medical field. In the transportation process of the stem cells, the interior of the transportation and storage device needs to be kept in an ultralow-temperature environment, and the transportation and storage device is put into a dormant state through low temperature, so that the stem cells can be revived to treat diseases when needed. In the transportation process, stem cells are stored in the storage device, and the storage device is easy to be influenced by external temperature to generate the phenomenon of uneven temperature, so that the storage effect of the stem cells is influenced.
The existing stem cell low-temperature storage device is used for freezing and storing stem cells through liquid nitrogen, but the liquid nitrogen has volatility, so that the liquid nitrogen is obviously reduced along with the lapse of time, and when the liquid nitrogen is added into the traditional stem cell low-temperature storage device, the liquid nitrogen is troublesome, the number of the stored stem cells is relatively small, more stem cell storage devices are required to be used, and certain resource waste and transportation cost improvement are caused.
Disclosure of Invention
The invention aims to provide an ultralow-temperature cell transportation and storage device for stem cell research, which solves the problems in the background technology.
In order to solve the technical problems, the invention provides the following technical scheme: an ultralow-temperature cell transportation and storage device for stem cell research comprises a transportation box, wherein a storage box is arranged in the transportation box, a cooling pipe is arranged above the storage box in the transportation box, a control box is arranged below the storage box, the cooling pipe is connected with a storage box pipeline, and the control box enables the storage box to be kept in a vertical state; the cooling tube extracts the outside air and heats the air through the hot junction of Peltier effect, the sterilization, the cooling tube cools down the hot air through the cold junction of Peltier effect once more, make the moisture condensation in the hot air become the water of low temperature, make the hot air cool down into the cold air, the cooling tube transmits the water of low temperature to the storage box in, the storage box cools down the stem cell through low-temperature water, the cooling tube infuses the box of storage box with the cold air, the cold air cools down to the box, prevent that box and low temperature water from carrying out heat and cold exchange and influence the effect of cold-stored stem cell.
A bearing plate is arranged inside the transport box;
inner ring shafts are arranged on two sides of the storage box, support rings are arranged on the two groups of inner ring shafts, two groups of outer ring shafts are arranged on the support rings at positions perpendicular to the two groups of inner ring shafts, and the two groups of outer ring shafts are arranged on the transport box; the storage box transversely rotates in the support ring through interior ring axis to make the storage box keep vertical when the transport case takes place horizontal slope, the storage box passes through the support ring and vertically rotates in the transport case, thereby make the storage box keep vertical when the transport case takes place to move about freely and quickly the slope, the storage box passes through the setting of support ring, remains vertical state throughout in the transport case, thereby when preventing that the transport case from taking place the slope, avoid the storage box to incline together with the transport case, avoid the stem cell to receive the slope influence and produce the damage.
The cooling pipe is arranged on the bearing plate, a fan is arranged in the cooling pipe, the cooling pipe comprises a heating section and a cooling section, the heating section is used for heating and sterilizing air, and the cooling section is used for cooling hot air so as to condense water in the hot air;
the control box is located under the lower end of the storage box, communicated with the interior of the storage box and electrically connected with the cooling pipe. The control box makes the gravity center of the storage box descend, and the control box carries out counterweight on the storage box, so that the storage box is in a vertical state under the support of the support ring.
The heating section and the cooling section are internally provided with a first semiconductor and a second semiconductor, a plurality of groups of connecting wires are arranged between the first semiconductor and the second semiconductor, the first semiconductor in the heating section is electrically connected with the first semiconductor in the cooling section, and the second semiconductor in the heating section is electrically connected with the second semiconductor in the cooling section. First semiconductor and second semiconductor communicate through a plurality of groups connecting wire, in the heating section part, the electric current flows to the second semiconductor through the connecting wire from first semiconductor, thereby make the inside connecting wire release heat of heating section, and heat the air through the heating section, bacterium in the air, virus etc. kill, in the cooling section part, the electric current flows to first semiconductor through the connecting wire from the second semiconductor, make the connecting wire of cooling section absorb heat, thereby make a plurality of groups connecting wire of cooling section cool down the hot-air, thereby make moisture in the hot-air and connecting wire contact and condensate water, make the hot-air cool down into cold air.
The cooling section is located the loading board below, and the cooling section is located the heating section under, the inside heating section that is located still is provided with heated board between first semiconductor and the second semiconductor, the one side that the fan was kept away from to heated board is provided with the third semiconductor, and the heated board lower extreme is provided with the fourth semiconductor, the fourth semiconductor other end is located the cooling section under, is located the cooling section inside be provided with the extension board on the fourth semiconductor, be provided with a plurality of groups of positive electric field silk on the third semiconductor, be provided with a plurality of groups of negative electric field silk, a plurality of groups of negative electric field silk sets up inside a plurality of groups of connecting wire in the cooling section. The heated plate is heated in the heating section, the heated plate, the third semiconductor and the fourth semiconductor are matched with each other to generate current through the Seebeck effect, a large number of positrons are accumulated on the third peninsula plate, a large number of negative electrons are accumulated on the fourth semiconductor, the positrons enable a plurality of groups of positive field wires to generate positive electric fields, the positive field wires polarize dust, particles and the like in the air, negative charges are accumulated on the outer layers of the dust and the particles, the outer layers of the dust and the particles form a polarized electric field, the negative electrons enable a plurality of groups of negative field wires to generate negative electric fields, when the dust and the particles polarized by the positive electric fields move to the periphery of the negative field wires under the carrying of the air, the dust and the particles are repelled by the negative electric fields generated by the negative field wires under the action of the polarized electric fields on the outer layers, the dust and the particles are prevented from further moving along with the air to the other end of the cooling pipe, and the dust and the particles are blocked by the negative electric fields, the air cooled in the cooling section flows to the other end of the cooling pipe, and separation of dust, particles and the air is improved through the arrangement of a positive electric field and a negative electric field; when hot air passes through the heat-absorbing connecting wire, the hot air is cooled, moisture in the hot air is condensed into water on the connecting wire, dust, particles, bacteria, viruses and the like in the air are driven by the air to be in contact with the connecting wire and are bound by water drops, so that the dust, the particles, the bacteria, the viruses and the like are separated from the air, and the separation effect is improved when the separation of the air from the dust, the particles and the like is realized through the repulsion of an electric field and the adsorption of the water drops on the connecting wire.
The below that lies in the cooling zone on the cooling tube is provided with the condensate pipe, a plurality of groups the other end of negative electric field silk is located the condensate pipe inside, a plurality of groups negative electric field silk and the cooling zone is inside if be provided with the drainage silk between organizing the connecting wire futilely, the cooling tube other end is provided with the air hose, condensate pipe and air hose all with support ring pipe connection.
The cooling tank that is the screw-tupe is seted up in the box of storage box, still is provided with into water channel and delivery channel in the box of storage box, support ring inside has been seted up into the transmission and has been led to the groove and go out the transmission and lead to the groove, and is a set of interior ring axle leads to the groove intercommunication with advancing the transmission, another group interior ring axle leads to the groove intercommunication with going out the transmission, and a set of interior ring axle that leads to the groove intercommunication with advancing the transmission passes through the one end intercommunication of pipeline and inhalant canal and cooling tank, and another group's interior ring axle that leads to the groove intercommunication with going out the transmission passes through the other end intercommunication of pipeline and delivery channel and cooling tank. During cold air entered into the air duct to cool down the storage box along the air duct, thereby avoid box and low temperature water to carry out cold and hot exchange, avoid the effect reduction of low temperature water to the stem cell cooling.
The interior of the storage box is provided with a cooling cotton, a plurality of groups of embedded grooves are formed in the cooling cotton, a cooling plate is arranged at the upper end of the cooling cotton, an embedded layer is arranged on the cooling cotton and located outside the cooling plate, the cooling plate is communicated with the water inlet channel, a spray hole is formed in one side, corresponding to the cooling cotton, of the cooling plate, a water outlet is formed in the position, corresponding to the control box, of the lower end of the storage box, the storage box is communicated with the interior of the control box, and the control box is communicated with the water outlet channel. The cooling cotton is sponge, the embedded layer laid on the outer side of the cooling cotton is a rubber layer, the test tube for storing stem cells is prevented from shaking when the transport box shakes through the arrangement of the sponge and the rubber, low-temperature water generated at the cooling tube enters the cooling plate through the water inlet through groove under the pressure of air provided by the fan, and sprayed onto the cooling cotton through the spray holes under the pressure of air, the water moves from top to bottom in the sponge and passes through the capillary tubes in the sponge, thereby slowing down the downward movement speed of water, prolonging the heat exchange time between the low-temperature water and the embedded layer, improving the cooling effect of the low-temperature water on the embedded layer, and then improve the cooling effect of embedding layer to the test tube, in the water in the sponge instils into the control box at last, the control box is in the pump through inside goes into outlet channel with the water pump to avoid water to keep vertical state to the storage box and produce the influence.
The buffer layer is arranged on the outer side of the transport box, the transit plate is arranged in the transport box and positioned below the control box, the transit plate is communicated with the output transmission through groove, and the buffer layer is connected with the transit plate through pipeline; the control box is characterized in that a partition plate is arranged in the control box, the partition plate divides the control box into a water storage space and a control space, the water storage space is communicated with the storage box, a monitoring system is arranged in the control space and comprises a temperature detection system, an alarm system and a control system, the temperature detection system and the alarm system are electrically connected with the control system, and the control system comprises a power supply. The transport case outside all is provided with the buffer layer on being in four terminal surfaces of vertical state, and the buffer layer is the gasbag, and four buffer layers all communicate with the transfer board, and all install the solenoid valve in the port with transfer board intercommunication, four solenoid valves and control system electric connection, when the transport case takes place the slope, control system infuses the buffer layer with the water and the air in the transfer board through the water pump fast to realize empting the buffering of transport case, reduce the vibrations that produce when empting.
The temperature detection system comprises a temperature sensor, the temperature sensor is electrically connected with the control system, and the temperature sensor is arranged on the storage box; the alarm system comprises a wireless transceiver and an angle monitoring assembly, the wireless transceiver is electrically connected with the control system and wirelessly connected with the mobile equipment, the angle monitoring assembly comprises a metal sensor, the metal sensor is electrically connected with the control system, and the metal sensor is arranged on the control box; four groups of metal strips are arranged on the outer side of the metal sensor on the transfer plate. Alarm system passes through wireless transceiver and connects the mobile device, like intelligent bracelet, cell-phone etc, when storage box inside high temperature and transport case took place the slope, alarm system takes place alarm signal to the mobile device in, make the transportation personnel inspect the transport case and right the transport case, metal sensor detects the metal strip, when the transport case took place the slope, metal sensor detects the metal strip, when detecting the signal, control system takes place alarm signal to the mobile device through alarm system.
And a small water pump is also arranged in the control box and pumps the water in the water storage space into the transmission through groove.
Compared with the prior art, the invention has the following beneficial effects:
1. according to the invention, the external air is directly extracted as a medium for cooling the stem cells, the cooling pipe heats and cools the hot air to simultaneously obtain cold air and low-temperature water, the stem cells are cooled by the low-temperature water, the box body of the storage box is cooled by the cold air, and the box body and the low-temperature water are prevented from performing cold-heat exchange by cooling the box body by the cold air, so that the influence of the box body on the cooling and transportation of the stem cells is reduced.
2. Water is inside from last down motion at the sponge, through the inside capillary of sponge to slow down the speed of water down motion, thereby make low-temperature water and the extension of the cold and hot exchange time between the embedding layer, make low-temperature water improve the cooling effect on embedding layer, and then improve the cooling effect of embedding layer to the test tube.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the principles of the invention and not to limit the invention. In the drawings:
FIG. 1 is a schematic view of the overall structure of the present invention;
FIG. 2 is a schematic view of the top of the carrier plate of the present invention;
FIG. 3 is a top view of the storage box of the present invention;
FIG. 4 is a schematic view of the position of the metal sensor and metal strip of the present invention;
FIG. 5 is a schematic view in half section of the overall structure of the present invention;
FIG. 6 is a schematic view of a half section of the storage tank of the present invention;
FIG. 7 is a schematic view of the position of the connecting wire and the positive field wire within the cooling tube of the present invention;
FIG. 8 is a top view showing the inner structure of the cooling tube according to the present invention;
fig. 9 is a schematic view of the connection between the first semiconductor and the second semiconductor of the present invention;
fig. 10 is a schematic structural view of the region a in fig. 5 according to the present invention.
In the figure: 1. a transport case; 2. a storage box; 3. a cooling tube; 4. a control box; 5. an air outlet pipe; 1-1, carrying plate; 1-2, a transfer plate; 1-3, a buffer layer; 1-4, metal strips; 2-1, inner ring shaft; 2-2, a support ring; 2-3, an outer ring shaft; 2-4, an embedding layer; 2-5, embedding the groove; 2-6, cooling tank; 2-7, cooling plates; 2-8, cooling cotton; 3-1, a fan; 3-2, a first semiconductor; 3-3, a second semiconductor; 3-4, connecting wires; 3-5, a heated plate; 3-6, a third semiconductor; 3-7, positive electric field wire; 3-8, a fourth semiconductor; 3-9, an extension plate; 3-10 parts of negative electric field wires; 3-11 parts of a condensate pipe; 3-12, air tube; 4-1, a partition plate; 4-2, and a metal sensor.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1 to 10, the present invention provides a technical solution: the utility model provides an ultra-low temperature cell transportation storage device is used in stem cell research, this transportation storage device includes transport case 1, and 1 internally mounted of transport case has storage box 2, and 1 inside storage box that is located installs cooling tube 3 above 2, and control box 4 is installed to 2 below storage boxes, and cooling tube 3 and 2 pipe connections in storage box, control box 4 make storage box 2 keep vertical state.
The conveying box is characterized in that a bearing plate 1-1 is arranged inside the conveying box 1, buffer layers 1-3 are respectively arranged on four vertical end faces outside the conveying box 1, the buffer layers 1-3 are of an air bag structure, a transfer plate 1-2 is arranged below a control box 4 inside the conveying box 1, the transfer plate 1-2 is of a hollow structure, the four buffer layers 1-3 are connected with the transfer plate 1-2 through pipelines, electromagnetic valves are arranged in the pipelines, the electromagnetic valves are electrically connected with the control box 4, and four groups of metal strips 1-4 are arranged on the transfer plate 1-2 and outside the metal sensors 4-2.
An air outlet pipe 5 is further arranged on one side of the cooling pipe 3 on the bearing plate 1-1, the air outlet pipe 5 is communicated with the outlet transmission through groove in the support ring 2-2 through a pipeline, and the air outlet pipe 5 is used for discharging used cold air.
Inner ring shafts 2-1 are installed on two sides of the storage box 2, the inner ring shafts 2-1 are of hollow structures, support rings 2-2 are installed on the two groups of inner ring shafts 2-1 together, a transmission inlet through groove and a transmission outlet through groove are formed in the support rings 2-2, layering is arranged in the transmission inlet through groove and the transmission outlet through groove and used for transmitting air and water respectively through layering, two groups of outer ring shafts 2-3 are installed on the support rings 2-2 and perpendicular to the two groups of inner ring shafts 2-1, and the two groups of outer ring shafts 2-3 are installed on the transport box 1 in a rotating mode.
A spiral cooling groove 2-6 is formed in the box body of the storage box 2, a water inlet channel and a water outlet channel are further formed in the box body of the storage box 2, one group of inner ring shafts 2-1 is communicated with the inlet transmission through groove, the other group of inner ring shafts 2-1 is communicated with the outlet transmission through groove, one group of inner ring shafts 2-1 communicated with the inlet transmission through groove is communicated with one ends of the water inlet channel and the cooling groove 2-6 through pipelines, and the other group of inner ring shafts 2-1 communicated with the outlet transmission through groove is communicated with the other ends of the water outlet channel and the cooling groove 2-6 through pipelines. The transfer plate 1-2 is communicated with the other end of the outlet transmission through groove, cold air is infused into the cooling groove 2-6, and low-temperature water flows into the water inlet channel and the water outlet channel.
The inner part of the storage box 2 is provided with cooling cotton 2-8, the cooling cotton 2-8 is provided with a plurality of groups of embedded grooves 2-5, the upper end of the cooling cotton 2-8 is provided with a cooling plate 2-7, the cooling plate 2-7 is connected with the storage box 2, an embedded layer 2-4 is laid on the cooling cotton 2-8 and positioned on the outer side of the cooling plate 2-7, the cooling plate 2-7 is communicated with the water outlet end of the water inlet channel, one side of the cooling plate 2-7 corresponding to the cooling cotton 2-8 is provided with a spray hole, the lower end of the storage box 2 is provided with a water outlet corresponding to the control box 4, and the storage box 2 is communicated with the inner part of the control box 4.
The cooling pipe 3 is arranged on the bearing plate 1-1, the cooling pipe 3 is of a U-shaped structure, the fan 3-1 is arranged in the cooling pipe 3, the cooling pipe 3 comprises a heating section and a cooling section, the heating section heats and sterilizes air, and the cooling section cools hot air to condense water from moisture in the hot air;
the heating section and the cooling section are internally provided with a first semiconductor 3-2 and a second semiconductor 3-3, a plurality of groups of connecting wires 3-4 are arranged between the first semiconductor 3-2 and the second semiconductor 3-3, the first semiconductor 3-2 in the heating section is electrically connected with the first semiconductor 3-2 in the cooling section, and the second semiconductor 3-3 in the heating section and the second semiconductor 3-3 in the cooling section are electrically connected with a power supply in the control box 4.
The cooling section is positioned below the bearing plate 1-1, the cooling section is positioned right below the heating section, a heated plate 3-5 is further arranged between the first semiconductor 3-2 and the second semiconductor 3-3 in the heating section, a third semiconductor 3-6 is arranged on one side, away from the fan 3-1, of the heated plate 3-5, a fourth semiconductor 3-8 is arranged at the lower end of the heated plate 3-5, the other end of the fourth semiconductor 3-8 penetrates through the tube body of the cooling tube 3 and the bearing plate 1-1 and is positioned in the cooling section right below the heating section, an extension plate 3-9 is arranged on the fourth semiconductor 3-8 in the cooling section, the extension plate 3-9 is a metal plate, a plurality of groups of positive field wires 3-7 are arranged on the third semiconductor 3-6, a plurality of groups of negative field wires 3-10 are arranged below the extension plate 3-9, the groups of negative electric field wires 3-10 are positioned inside the groups of connecting wires 3-4 in the cooling section, and the drainage wires are arranged between the groups of negative electric field wires 3-10 and the groups of connecting wires 3-4 inside the cooling section, such as a dry group.
And a condensate pipe 3-11 is arranged below the cooling section on the cooling pipe 3, the other ends of the groups of negative electric field wires 3-10 are arranged in the condensate pipe 3-11, an air pipe 3-12 is arranged at the other end of the cooling pipe 3, and the condensate pipe 3-11 and the air pipe 3-12 are communicated with the feeding and conveying through groove of the support ring 2-2 through pipelines.
The control box 4 is located under the lower end of the storage box 2, a partition plate 4-1 is installed inside the control box 4, the control box 4 is divided into a water storage space and a control space by the partition plate 4-1, the water storage space is communicated with the storage box 2, a monitoring system is arranged inside the control space and comprises a temperature detection system, an alarm system and a control system, the temperature detection system and the alarm system are both electrically connected with the control system, and the control system comprises a power supply.
The control box 4 lowers the center of gravity of the storage box 2, and the control box 4 weights the storage box 2 so that the storage box 2 is in a vertical state supported by the support rings 2-2.
The temperature detection system comprises a temperature sensor which is electrically connected with the control system, and the temperature sensor is arranged on the storage box 2;
the alarm system comprises a wireless transceiver and an angle monitoring assembly, the wireless transceiver is electrically connected with the control system and wirelessly connected with the mobile device, the angle monitoring assembly comprises a metal sensor 4-2, the metal sensor 4-2 is electrically connected with the control system, and the metal sensor 4-2 is arranged on the control box 4.
The control box 4 is also provided with a small water pump and a transmission pipeline, when the transmission box 1 is not inclined, the small water pump pumps water in the water storage space and infuses the water into the transit plate 1-2, and when the transmission box is inclined, the control system switches the transmission pipeline, so that the small water pump pumps the water in the transit plate 1-2 and transmits the water to the buffer layer 1-3, and the buffer layer 1-3 is rapidly expanded.
The working principle of the invention is as follows:
the test tubes with the stem cells are inserted into the embedded grooves 2-5, the fan 3-1 extracts outside air, the air is heated after passing through the heating section, bacteria and viruses in the air are killed by high temperature, dust and particles in the air are polarized by a positive electric field generated by the positive electric field wires 3-7, when the heated air flows to the cooling section, the negative electric field generated by the negative electric field wires 3-10 blocks the dust and the particles, the dust and the particles are prevented from entering the air tubes 3-12, the temperature of the connecting wires 3-4 of the cooling section is reduced, moisture in the hot air is condensed into water on the connecting wires 3-4, and the water adsorbs the dust and the particles in the air, so that the separation of the dust, the particles, the bacteria and the viruses from the air is realized.
The low-temperature water enters the inlet and delivery through groove in the support ring 2-2 through the condensate pipe 3-11, the cold air enters the inlet and delivery through groove in the support ring 2-2 through the air pipe 3-12 and the pipeline, and the cold air and the low-temperature water in the inlet and delivery through groove respectively enter the cooling groove 2-6 and the water inlet channel through the inner ring shaft 2-1;
cold air flows in the cooling grooves 2-6 to realize the cooling of the box body of the storage box 2-2, the cold air enters the cooling grooves 2-6 through one group of inner ring shafts 2-1, flows in the cooling grooves 2-6 and is cooled, then enters the air outlet pipe 5 through the other group of inner ring shafts 2-1, the outlet transmission through groove and the pipeline, and finally the storage device is removed;
the low-temperature water enters the cooling plate 2-7 through the water inlet through groove under the pressure of air provided by the fan 3-1 and is sprayed onto the cooling sponge 2-8 through the spray holes under the pressure of the air, the water moves from top to bottom inside the cooling sponge 2-8, namely the sponge, and passes through the capillary tube inside the sponge, so that the speed of the downward movement of the water is reduced, the heat exchange time between the low-temperature water and the embedded layer 2-4 is prolonged, the cooling effect of the low-temperature water on the embedded layer 2-4 is improved, the cooling effect of the embedded layer 2-4 on a test tube is improved, the water in the sponge finally drops into the water storage space in the control box 4, the control box 4 pumps the water into the water outlet channel through the small-sized water pump inside, the water enters the transit plate 1-2 through the other group of inner ring shafts 2-1, the outlet transmission through groove and the pipeline, and stored in the transit board 1-2.
When the transport case 1 inclines, the storage box 2 rotates in the transport case 1 to keep a vertical state, meanwhile, the metal sensor 4-2 detects the metal strip 1-4 when the transport case 1 inclines and obtains an inclination signal, the control system opens the electromagnetic valve in the buffer layer 1-3 on the corresponding inclined surface after obtaining the inclination signal, and simultaneously controls the small water pump to transmit water to the buffer layer 1-3 to enable the buffer layer 1-3 to expand rapidly, so that the transport case 1 is prevented from colliding with the ground directly after inclining, a buffering effect is achieved, the influence of vibration generated after the transport case 1 is overturned on stem cells is avoided, after the transport case 1 is righted, the control system controls the small water pump to suck water in the buffer layer 1-3 reversely and transmit the water to the transfer plate 1-2 again, and after no water exists in the buffer layer 1-3, the control system switches the transfer line again to a communication state in which the transport box 1 is not tilted.
When the transport case 1 inclines, the control system generates an inclination signal to the mobile device through the alarm system, so that the transport personnel can timely know the condition of the transport case 1 after keeping away from the storage case 1.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that changes may be made in the embodiments and/or equivalents thereof without departing from the spirit and scope of the invention. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (9)
1. The utility model provides an ultra-low temperature cell transportation storage device is used in stem cell research which characterized in that: the transportation and storage device comprises a transportation box (1), wherein a storage box (2) is arranged in the transportation box (1), a cooling pipe (3) is arranged above the storage box (2) in the transportation box (1), a control box (4) is arranged below the storage box (2), the cooling pipe (3) is connected with the storage box (2) through a pipeline, and the control box (4) enables the storage box (2) to keep a vertical state;
a bearing plate (1-1) is arranged inside the transport box (1);
inner ring shafts (2-1) are arranged on two sides of the storage box (2), support rings (2-2) are arranged on the two groups of inner ring shafts (2-1), two groups of outer ring shafts (2-3) are arranged on the support rings (2-2) in a position perpendicular to the two groups of inner ring shafts (2-1), and the two groups of outer ring shafts (2-3) are arranged on the transport box (1);
the cooling pipe (3) is arranged on the bearing plate (1-1), the fan (3-1) is arranged in the cooling pipe (3), the cooling pipe (3) comprises a heating section and a cooling section, the heating section heats and sterilizes air, and the cooling section cools hot air to condense water in the hot air;
the control box (4) is located under the lower end of the storage box (2), the control box (4) is communicated with the interior of the storage box (2), and the control box (4) is electrically connected with the cooling pipe (3).
2. The ultra-low temperature cell transportation and storage device for stem cell research according to claim 1, wherein: the heating section and the cooling section are internally provided with a first semiconductor (3-2) and a second semiconductor (3-3), a plurality of groups of connecting wires (3-4) are arranged between the first semiconductor (3-2) and the second semiconductor (3-3), the first semiconductor (3-2) in the heating section is electrically connected with the first semiconductor (3-2) in the cooling section, and the second semiconductor (3-3) in the heating section is electrically connected with the second semiconductor (3-3) in the cooling section.
3. The ultra-low temperature cell transportation and storage device for stem cell research, according to claim 2, is characterized in that: the cooling section is positioned below the bearing plate (1-1), the cooling section is positioned under the heating section, a heated plate (3-5) is further arranged between the first semiconductor (3-2) and the second semiconductor (3-3) in the heating section, a third semiconductor (3-6) is arranged on one side, away from the fan (3-1), of the heated plate (3-5), a fourth semiconductor (3-8) is arranged at the lower end of the heated plate (3-5), the other end of the fourth semiconductor (3-8) is positioned in the cooling section under the heating section, an extension plate (3-9) is arranged on the fourth semiconductor (3-8) in the cooling section, a plurality of groups of positive electric field wires (3-7) are arranged on the third semiconductor (3-6), a plurality of groups of negative electric field wires (3-10) are arranged under the extension plate (3-9), a plurality of groups of the negative electric field wires (3-10) are arranged inside a plurality of groups of the connecting wires (3-4) in the cooling section.
4. The ultra-low temperature cell transportation and storage device for stem cell research, according to claim 3, is characterized in that: a condensate pipe (3-11) is arranged below the cooling section on the cooling pipe (3), the other ends of the negative field wires (3-10) are arranged in the condensate pipe (3-11), the negative field wires (3-10) and the connecting wires (3-4) in the cooling section are provided with a diversion wire, the other ends of the cooling pipe (3) are provided with air pipes (3-12), and the condensate pipe (3-11) and the air pipes (3-12) are all connected with the support ring (2-2) through pipelines.
5. The ultra-low temperature cell transportation and storage device for stem cell research, according to claim 4, is characterized in that: the cooling device is characterized in that a spiral cooling groove (2-6) is formed in a box body of the storage box (2), a water inlet channel and a water outlet channel are further arranged in the box body of the storage box (2), a transmission inlet through groove and a transmission outlet through groove are formed in the support ring (2-2), one group of inner ring shafts (2-1) is communicated with the transmission inlet through groove, the other group of inner ring shafts (2-1) is communicated with the transmission outlet through groove, one group of inner ring shafts (2-1) communicated with the transmission inlet through groove are communicated with one ends of the water inlet channel and the cooling groove (2-6) through a pipeline, and the other group of inner ring shafts (2-1) communicated with the transmission outlet through groove are communicated with the other ends of the water outlet channel and the cooling groove (2-6) through a pipeline.
6. The ultra-low temperature cell transportation and storage device for stem cell research, according to claim 5, is characterized in that: the cooling cotton (2-8) is arranged inside the storage box (2), a plurality of groups of embedded grooves (2-5) are formed in the cooling cotton (2-8), the cooling plate (2-7) is arranged at the upper end of the cooling cotton (2-8), an embedded layer (2-4) is arranged on the cooling cotton (2-8) and located on the outer side of the cooling plate (2-7), the cooling plate (2-7) is communicated with the water inlet channel, a spray hole is formed in one side, corresponding to the cooling cotton (2-8), of the cooling plate (2-7), a water outlet is formed in the position, corresponding to the control box (4), of the lower end of the storage box (2), the storage box (2) is communicated with the inside of the control box (4), and the control box (4) is communicated with the water outlet channel.
7. The ultra-low temperature cell transportation and storage device for stem cell research according to claim 6, wherein: the buffer layer (1-3) is arranged on the outer side of the transport box (1), the transit plate (1-2) is arranged in the transport box (1) and located below the control box (4), the transit plate (1-2) is communicated with the output transmission through groove, and the buffer layer (1-3) is connected with the transit plate (1-2) through a pipeline; the control box is characterized in that a partition plate (4-1) is arranged inside the control box (4), the control box (4) is divided into a water storage space and a control space by the partition plate (4-1), the water storage space is communicated with the storage box (2), a monitoring system is arranged inside the control space and comprises a temperature detection system, an alarm system and a control system, the temperature detection system and the alarm system are both electrically connected with the control system, and the control system comprises a power supply.
8. The ultra-low temperature cell transportation and storage device for stem cell research, according to claim 7, wherein: the temperature detection system comprises a temperature sensor, the temperature sensor is electrically connected with the control system, and the temperature sensor is arranged on the storage box (2); the alarm system comprises a wireless transceiver and an angle monitoring assembly, the wireless transceiver is electrically connected with the control system and wirelessly connected with the mobile equipment, the angle monitoring assembly comprises a metal sensor (4-2), the metal sensor (4-2) is electrically connected with the control system, and the metal sensor (4-2) is arranged on the control box (4); four groups of metal strips (1-4) are arranged on the outer side of the metal sensor (4-2) on the transfer plate (1-2).
9. The ultra-low temperature cell transportation and storage device for stem cell research according to claim 8, wherein: and a small water pump is also arranged in the control box (4) and pumps the water in the water storage space into the transmission through groove.
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| CN202210149378.2A CN114190370A (en) | 2022-02-18 | 2022-02-18 | Ultralow temperature cell transportation and storage device for stem cell research |
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| CN202210149378.2A CN114190370A (en) | 2022-02-18 | 2022-02-18 | Ultralow temperature cell transportation and storage device for stem cell research |
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| CN202210149378.2A Pending CN114190370A (en) | 2022-02-18 | 2022-02-18 | Ultralow temperature cell transportation and storage device for stem cell research |
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