CN114184801A - A pipelined biochemical analysis appearance for detecting protoheme of histocyte - Google Patents

A pipelined biochemical analysis appearance for detecting protoheme of histocyte Download PDF

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Publication number
CN114184801A
CN114184801A CN202111416348.5A CN202111416348A CN114184801A CN 114184801 A CN114184801 A CN 114184801A CN 202111416348 A CN202111416348 A CN 202111416348A CN 114184801 A CN114184801 A CN 114184801A
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cuvette
sample
carrier
detection
fixing plate
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蒋春亮
郑德春
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Shandong Tianni Biological Technology Co ltd
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Shandong Tianni Biological Technology Co ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009Characterised by arrangements for controlling the aspiration or dispense of liquids

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The invention provides a production line type biochemical analyzer for detecting protoheme of tissue cells, which comprises an analysis platform, a running track, a code scanning gun, a pushing fixing plate, a cuvette carrier assembly, a sample placing area, a disposable TIP head, a cuvette incubation detection assembly, a sample adding arm module, a pushing motion sensor and a carrier optical coupler, wherein the sample adding arm module is arranged on the cuvette carrier assembly; according to the invention, the cuvette carrier assembly, the sample placing area and the cuvette incubation detection assembly are arranged, a plurality of cuvette placing racks and disposable colorimetric cups are placed on the cuvette carrier, a plurality of samples are placed on the sample carrier in the sample placing area, and the cuvette incubation detection assembly simultaneously detects the plurality of disposable colorimetric cups, so that the detection requirements of a large number of samples are met; the setting of cell carrier subassembly places a plurality of cell racks on the cell carrier and once only compares the color cup, and adopts once only than the color cup, need not to wash after the use, saves a large amount of water, and detection efficiency is high.

Description

A pipelined biochemical analysis appearance for detecting protoheme of histocyte
Technical Field
The invention belongs to the technical field of biochemical analyzers for protoheme of histiocytes, and particularly relates to a pipeline biochemical analyzer for detecting protoheme of histiocyte.
Background
The full-automatic biochemical analyzer is used for quantitative detection of biochemistry and chemical components in clinical body fluid samples, is a conventional inspection instrument in modern hospitals, has two tissue cell protoheme detection reagents, and has no reaction between R1 and R2, so that a R1+ R2+ S sample adding mode can be adopted, and a full-automatic detection platform can use the full-automatic biochemical analyzer.
Most of the existing small-sized discrete biochemical analyzers can only add one reagent and one sample in each period, and the number of the colorimetric cups and sample tubes is small, so that the existing biochemical analyzers have very low working efficiency, cannot meet the requirements of large-batch samples, and only can buy large-sized instruments or splice instruments of the same type for use; meanwhile, the sample adding and reagent adding adopt steel needles, so that cross contamination cannot be avoided, and the water consumption for cleaning the cuvette is large.
Therefore, it is necessary to invent a pipelined biochemical analyzer for detecting protoheme of tissue cells.
Disclosure of Invention
In order to solve the technical problems, the invention provides a pipeline biochemical analyzer for detecting protoheme of tissue cells, which aims to solve the problems that most of the existing small-sized discrete biochemical analyzers can only add one reagent and one sample in each period, and the number of cuvettes and sample tubes is small, so that the existing biochemical analyzer has very low working efficiency, cannot meet the requirements of large-batch samples, and only can be purchased to large-scale instruments or spliced to the same type of instruments; simultaneously, the application of sample adds the reagent and all adopts the steel needle, can't avoid cross contamination, and washs the big problem of cell water consumption. A production line type biochemical analyzer for detecting protoheme of tissue cells comprises an analysis platform, a running track, a code scanning gun, a pushing fixing plate, a cuvette carrier assembly, a sample placing area, a disposable TIP head, a cuvette incubation detection assembly, a sample adding arm module, a pushing motion sensor and a carrier optocoupler, wherein the running track is arranged on the lower side above the analysis platform; the code scanning gun is clamped on the running track; the propelling fixing plate is arranged at one end above the analysis platform; the pushing fixing plate is arranged at one end, deviating from the pushing fixing plate, above the analysis platform; the carrier opto-couplers are multiple, and are arranged on the inner sides of the pushing fixing plate and the pushing fixing plate; the cuvette carrier assembly is arranged between the pushing and fixing plates; the sample placing area is arranged at the lower side between the pushing fixing plate and the pushing fixing plate; the disposable TIP head is arranged on the upper side between the pushing fixing plate and the pushing fixing plate; the cuvette incubation detection assembly is arranged on the upper side above the analysis platform; the sample adding arm module is arranged above the analysis platform and is positioned between the disposable TIP head and the push-out fixing plate; the propelling movement sensor is arranged on one side, close to the propelling fixing plate, of the upper end above the analysis platform; the push-out motion sensor is arranged on one side, close to the push-out fixing plate, of the upper end of the upper part of the analysis platform;
the cuvette carrier assembly comprises a cuvette carrier, a cuvette placing rack and a disposable cuvette, and the cuvette carrier is arranged between the pushing fixing plates; a plurality of colorimetric cup placing frames are adopted, and the colorimetric cup placing frames are arranged above the colorimetric cup carrying frame; the disposable color cups are arranged on the side face of the cuvette placing frame.
Preferably, the cuvette incubation detection assembly comprises a cuvette incubation detection plate, a detection module, a detection optocoupler, a reagent adding optocoupler and a sample adding photocoupler, wherein the cuvette incubation detection plate is arranged on the upper side above the analysis platform; the detection modules are arranged above the cuvette incubation detection plate; the detection optocoupler is arranged at one end, close to the propulsion fixing plate, of the cuvette incubation detection plate; the sample adding optocoupler is arranged in the middle of the cuvette incubation detection plate; add reagent opto-coupler and install on the pick-up plate is hatched to the cell, and add reagent opto-coupler and be located between this opto-coupler of detection opto-coupler and application of sample.
Preferably, the production line type biochemical analyzer for detecting the protoheme of the tissue cells further comprises an electric control cabinet and a PLC (programmable logic controller), wherein the electric control cabinet is arranged below the analysis platform and is connected with a mains supply through a power line, and the electric control cabinet is used for supplying power to the analyzer; the PLC controller is installed below the analysis platform and connected with the electric control cabinet through a wire, and the PLC controller is used for controlling the analyzer.
Preferably, the code scanning gun is connected with the running track in a sliding manner, and the running track is used for guiding and supporting the code scanning gun; the pushing fixing plate and the pushing fixing plate are symmetrically arranged; the sample placing area is used for placing a sample; the disposable TIP head is used for sucking reagents and samples; the sample adding arm module is connected with the PLC and the electric control cabinet through wires respectively, and is used for clamping the disposable TIP head and performing needle removal operation.
Preferably, the propulsion motion sensor is respectively connected with the PLC and the electric control cabinet through wires and is used for sensing the propulsion of the cuvette; the push-out motion sensor is respectively connected with the PLC and the electric control cabinet through leads and is used for sensing the push-out of the cuvette; the carrier optical coupler is respectively connected with the PLC and the electric control cabinet through wires.
Preferably, the cuvette carrier is used for supporting the colorimetric cup placing frame and the disposable colorimetric cup; the cuvette placing frames are uniformly distributed above the cuvette carrier frame, and the cuvette placing frames are used for installing disposable colorimetric cups; the number of the disposable colorimetric cups is the same as that of the colorimetric cup placing frames.
Preferably, the detection module is used for installing a detection optocoupler; the detection optocoupler is respectively connected with the PLC and the electric control cabinet through wires, and the detection optocoupler detects the cuvette; the reagent adding optical coupler is respectively connected with the PLC and the electric control cabinet through leads and is used for sensing the action of a reagent; the sample adding optical coupler is respectively connected with the PLC and the electric control cabinet through wires, and the sample adding optical coupler is used for sensing sample adding actions.
A use method of a flow line type biochemical analyzer for detecting protoheme of tissue cells is characterized in that: the use method of the assembly line type biochemical analyzer for detecting the protoheme of the tissue cells comprises the following steps:
step S101: preparing for instrument detection, and checking whether the reagent bottle is sufficient; placing a sample carrier on which a sample is placed in advance in a sample placing area; the code scanning gun records the sample carrier number and the sample bar code; placing a cuvette placing frame in which a disposable colorimetric cup is placed in advance on a cuvette carrier; the left side of the colorimetric cup carrier assembly is buckled with a protruding flanging of the positioning baffle, and a lower groove is buckled with a triangular shifting sheet on the table top; the code scanning gun records the number of the cuvette carrier;
step S102: the cuvette is pushed forward by the cuvette pushing mechanism, the carriage optocoupler at the position of the pushing fixed plate displays green when the cuvette carriage assembly exists, the carriage optocoupler at the position of the pushing fixed plate displays red when the cuvette carriage assembly does not exist, the cuvette carriage assembly is pushed until the area to be measured, and then the cuvette pushing is stopped;
step S103: detecting a cuvette, starting rightward propulsion, reading a blank of a disposable cuvette by a detection unit when the cuvette carrier assembly completely enters the cuvette incubation detection assembly, sensing to start reagent adding at a reagent adding position, after the reagent is added, enabling a corresponding reagent adding optocoupler to be red, restarting a propulsion mechanism at the left side of the disposable cuvette to propel a subsequent cuvette carrier assembly to enter a region to be detected, and circularly moving; simultaneously, after the reagent is added, the cuvette carrier assembly moves to the sample adding sensor, the sample adding arm module starts to suck the suction head and the sample, the next disposable colorimetric cup position waits for conveying the disposable colorimetric cup for sample adding, the disposable TIP head sucks and mixes the sample back after the sample adding, then the needle is removed, the suction head and the sample are sucked, and the process is circulated in a reciprocating way;
step S104: the cuvette is pushed out, the result is read, the cuvette carrier assembly moves to the pushing-out area, the cuvette carrier assembly is sensed to the pushing-out motion sensor, the cuvette carrier assembly is pushed out in a back-and-forth reciprocating motion mode, the carrier optocoupler which is pushed out of the fixed plate when the cuvette carrier assembly exists displays red, the carrier optocoupler which is pushed out of the fixed plate when the cuvette carrier assembly does not exist displays green, and finally the cuvette carrier assembly is taken out manually and can be continuously used after the used disposable cuvette is processed.
Compared with the prior art, the invention has the following beneficial effects:
1. according to the arrangement of the cuvette carrier assembly, the sample placing area and the cuvette incubation detection assembly, the plurality of cuvette placing frames and the disposable colorimetric cups are placed on the cuvette carrier, the plurality of samples are placed on the sample carrier in the sample placing area, and the cuvette incubation detection assembly simultaneously detects the plurality of disposable colorimetric cups, so that the working efficiency of the biochemical analyzer is improved, and the detection requirements of a large number of samples are met.
2. The disposable TIP head is arranged, the disposable TIP head is used for sample adding, cleaning is not needed, and cross contamination of samples is avoided; the reagent adding needles are two independent steel needles respectively, cleaning is not needed, the reagent is added firstly, cross contamination is avoided, the three reagent adding needles can independently operate simultaneously, and the working efficiency is high.
3. According to the arrangement of the carrier optocoupler, the carrier optocoupler senses the color cup carrier assembly, and is matched with the PLC to realize automatic control of the biochemical analyzer, so that the operation precision of the biochemical analyzer is ensured, and the automation degree of the biochemical analyzer is improved.
4. According to the arrangement of the cuvette incubation detection assembly, the cuvette incubation detection assembly is used for automatically detecting a disposable cuvette, the reagent adding optical coupler is used for sensing the action of a reagent, the sample adding optical coupler is used for sensing the action of a sample, the PLC controls the sample adding arm module to add the reagent and sample according to the sensing results of the reagent adding optical coupler and the sample adding optical coupler, and the working efficiency of a biochemical analyzer is improved.
5. According to the arrangement of the cuvette carrier assembly, the cuvette carrier is provided with the plurality of disposable colorimetric cup placing frames and the disposable colorimetric cups, and the disposable colorimetric cups are adopted, so that the disposable colorimetric cups do not need to be cleaned after use, a large amount of water is saved, and the detection efficiency is high.
Drawings
Fig. 1 is a schematic structural view of the present invention.
Figure 2 is a schematic diagram of the construction of the cuvette carrier assembly according to the invention.
Figure 3 is a schematic diagram of the structure of the cuvette incubation detection assembly according to the invention.
Fig. 4 is a flow chart of a method of use of the present invention.
In the figure:
1-analysis platform, 2-orbit, 3-yard-scanning gun, 4-propulsion fixed plate, 5-propulsion fixed plate, 6-cuvette carrier assembly, 61-cuvette carrier, 62-cuvette holder, 63-disposable colorimetric cuvette, 7-sample placement area, 8-disposable TIP, 9-cuvette incubation detection assembly, 91-cuvette incubation detection plate, 92-detection module, 93-detection optocoupler, 94-reagent-adding optocoupler, 95-sample-adding optocoupler, 10-sample-adding arm module, 11-propulsion motion sensor, 12-propulsion motion sensor, 13-optocoupler carrier.
Detailed Description
The invention is further described below with reference to the accompanying drawings:
example (b):
as shown in figures 1 to 4
The invention provides a production line type biochemical analyzer for detecting protoheme of tissue cells, which comprises an analysis platform 1, a running track 2, a code scanning gun 3, a pushing fixing plate 4, a pushing fixing plate 5, a cuvette carrier assembly 6, a sample placing area 7, a disposable TIP head 8, a cuvette incubation detection assembly 9, a sample adding arm module 10, a pushing motion sensor 11, a pushing motion sensor 12 and a carrier optical coupler 13, wherein the running track 2 is arranged on the lower side above the analysis platform 1; the code scanning gun 3 is clamped on the running track 2; the propelling fixing plate 4 is arranged at one end above the analysis platform 1; the pushing fixing plate 5 is arranged at one end, deviating from the pushing fixing plate 4, above the analysis platform 1; a plurality of carrier optical couplers 13 are adopted, and the carrier optical couplers 13 are arranged on the inner sides of the pushing fixing plate 4 and the pushing fixing plate 5; the cuvette carrier assembly 6 is arranged between the pushing and fixing plates 4; the specimen placing region 7 is provided on the lower side between the push-in fixing plate 4 and the push-out fixing plate 5; the disposable TIP head 8 is arranged on the upper side between the pushing fixing plate 4 and the pushing fixing plate 5; the cuvette incubation detection assembly 9 is arranged on the upper side above the analysis platform 1; the sample adding arm module 10 is arranged above the analysis platform 1, and the sample adding arm module 10 is positioned between the disposable TIP head 8 and the push-out fixing plate 5; the propelling movement sensor 11 is arranged at one side of the upper end of the upper part of the analysis platform 1, which is close to the propelling fixing plate 4; the push-out motion sensor 12 is arranged at one side of the upper end of the upper part of the analysis platform 1 close to the push-out fixing plate 5; the code scanning gun 3 is connected with the running track 2 in a sliding mode, and the running track 2 is used for guiding and supporting the code scanning gun 3; the pushing fixing plate 4 and the pushing fixing plate 5 are symmetrically arranged; the sample placing area 7 is used for placing a sample; the disposable TIP 8 is used for sucking reagent and sample; the sample adding arm module 10 is respectively connected with the PLC and the electric control cabinet through leads, and the sample adding arm module 10 is used for clamping the disposable TIP head 8 to move and perform needle removal operation; the propelling movement sensor 11 is respectively connected with the PLC and the electric control cabinet through leads, and the propelling movement sensor 11 is used for sensing the propelling of the cuvette; the push-out motion sensor 12 is respectively connected with the PLC and the electric control cabinet through leads, and the push-out motion sensor 12 is used for sensing the push-out of the cuvette; the carrier optical coupler 13 is respectively connected with the PLC and the electric control cabinet through wires; the sample is added by adopting the disposable TIP head 8, and the sample is not required to be cleaned, so that the cross contamination of the sample is avoided; the reagent adding needles are two independent steel needles respectively, cleaning is not needed, the reagent is added firstly, cross contamination is avoided, the three sample adding and reagent adding needles can independently operate at the same time, and the working efficiency is high; the carrier optical coupler 13 senses the color cup carrier assembly 6, and is matched with a PLC (programmable logic controller) to realize the automatic control of the biochemical analyzer, so that the operation precision of the biochemical analyzer is ensured, and the automation degree of the biochemical analyzer is improved.
In this embodiment, specifically, the cuvette carrier assembly 6 comprises a cuvette carrier 61, a cuvette holder 62 and a disposable cuvette 63, the cuvette carrier 61 being arranged between the push fixing plates 4; a plurality of cuvette holders 62 are provided, and the cuvette holders 62 are mounted above the cuvette carrier 61; a plurality of disposable color cups 63 are adopted, and the disposable color cups 63 are arranged on the side surface of the cuvette placing rack 62; the cuvette carrier 61 is used to support a colorimetric cup holder 62 and a disposable colorimetric cup 63; the cuvette placing racks 62 are uniformly distributed above the cuvette carrier 61, and the cuvette placing racks 62 are used for installing the disposable cuvette 63; the number of the disposable colorimetric cups 63 is the same as that of the colorimetric cup placing frames 62; a plurality of colorimetric cup placing frames 62 and disposable colorimetric cups 63 are placed on the colorimetric cup carrier 61, a plurality of samples are placed on the sample carrier in the sample placing area 7, and the colorimetric cup incubation detection assembly 9 detects a plurality of disposable colorimetric cups 63 at the same time, so that the working efficiency of the biochemical analyzer is improved, and the detection requirements of a large number of samples are met; place a plurality of cell racks 62 on the cell carrier 61 and once only compare color cup 63, and adopt once only to compare color cup 63, need not to wash after the use, save a large amount of water, detection efficiency is high.
In this embodiment, specifically, the cuvette incubation detection assembly 9 includes a cuvette incubation detection plate 91, a detection module 92, a detection optocoupler 93, a reagent adding optocoupler 94 and a sample adding optocoupler 95, and the cuvette incubation detection plate 91 is installed on the upper side above the analysis platform 1; a plurality of detection modules 92 are adopted, and the detection modules 92 are arranged above the cuvette incubation detection plate 91; the detection optocoupler 93 is arranged at one end of the cuvette incubation detection plate 91 close to the propulsion fixing plate 4; the sample adding optocoupler 95 is arranged in the middle of the cuvette incubation detection plate 91; the reagent adding optical coupler 94 is arranged on the cuvette incubation detection plate 91, and the reagent adding optical coupler 94 is positioned between the detection optical coupler 93 and the sample adding optical coupler 95; the detection module 92 is used for installing a detection optocoupler 93; the detection optocoupler 93 is respectively connected with the PLC and the electric control cabinet through a wire, and the detection optocoupler 93 detects the colorimetric cups; the reagent adding optical coupler 94 is respectively connected with the PLC and the electric control cabinet through leads, and the reagent adding optical coupler 94 is used for sensing the action of a reagent; the sample adding optical coupler 95 is respectively connected with the PLC and the electric control cabinet through wires, and the sample adding optical coupler 95 is used for sensing sample adding actions; detection component 9 is hatched to cell carries out automated inspection to disposable than color cup 63, adds reagent opto-coupler 94 simultaneously and is used for the response to add the reagent action, and this opto-coupler 95 of application of sample is used for the response to add the sample action, and the PLC controller controls application of sample arm module 10 according to adding this opto-coupler 94 of reagent and application of sample's response result and adds this operation of reagent and application of sample, improves biochemical analyzer's work efficiency.
In this embodiment, the pipelined biochemical analyzer for detecting protoheme in tissue cells further includes an electric control cabinet and a PLC controller, the electric control cabinet is installed below the analysis platform 1, and is connected to a mains supply through a power line, and the electric control cabinet is used for supplying power to the analyzer; the PLC controller is installed in the below of analysis platform 1, and the PLC controller passes through the wire and links to each other with automatically controlled cabinet, and this PLC controller is used for controlling the analysis appearance.
A use method of a flow line type biochemical analyzer for detecting protoheme of tissue cells is characterized in that: the use method of the assembly line type biochemical analyzer for detecting the protoheme of the tissue cells comprises the following steps:
step S101: preparing for instrument detection, and checking whether the reagent bottle is sufficient; placing a sample carrier on which a sample is placed in advance in the sample placement area 7; the code scanning gun 3 records the sample carrier number and the sample bar code; placing a cuvette placing rack 62 in which a disposable colorimetric cup 63 is placed in advance on a cuvette carrier 61; the left side of the cuvette carrier assembly 6 is buckled with a protruding flanging of the positioning baffle, and a lower groove is buckled with a triangular shifting sheet on the table top; the code scanning gun 3 records the number of the cuvette carrier;
step S102: the cuvette is pushed forward by the cuvette pushing mechanism, the carriage optocoupler 13 at the fixed plate 4 is pushed to display green when the cuvette carriage assembly 6 is arranged, the carriage optocoupler 13 at the fixed plate 4 is pushed to display red when the cuvette carriage assembly 6 is not arranged, the cuvette carriage assembly 6 is pushed until the area to be measured, and the forward pushing is stopped at the moment;
step S103: detecting the cuvette, starting to push the cuvette to move rightwards, reading the blank of the disposable cuvette 63 by a detection unit when the cuvette carrier assembly 6 completely enters the cuvette incubation detection assembly 9, sensing the reagent to be added, starting to add the reagent, finishing adding the reagent, enabling the corresponding reagent optical coupler 94 to be red, restarting a pushing mechanism on the left side of the disposable cuvette 63 to push the subsequent cuvette carrier assembly 6 to enter a region to be detected, and circularly moving; simultaneously, after the reagent is added, the cuvette carrier assembly 6 moves to the sample filling sensor, the sample adding arm module 10 starts to suck the suction head and the sample, waits for the transmission of the sample adding of the disposable colorimetric cup 63 at the next disposable colorimetric cup 63 position, sucks the disposable TIP head 8 back and uniformly after the sample adding, then takes off the needle, sucks the suction head and the sample, and circulates in a reciprocating way;
step S104: the cuvette is pushed out, the result is read, the cuvette carrier assembly 6 moves to the pushing-out area, the sensor is connected to the pushing-out motion sensor 12, the cuvette carrier assembly 6 is pushed out by reciprocating back and forth, the carrier optocoupler 13 at the fixed plate 5 is pushed out to display red when the cuvette carrier assembly 6 exists, the carrier optocoupler 13 at the fixed plate 5 is pushed out to display green when the cuvette carrier assembly 6 does not exist, and finally, the cuvette carrier assembly 6 can be used continuously after being taken out manually and processed into a disposable cuvette 63.
The technical solutions of the present invention or similar technical solutions designed by those skilled in the art based on the teachings of the technical solutions of the present invention are all within the scope of the present invention to achieve the above technical effects.

Claims (8)

1. A pipelined biochemical analyzer for detecting histocyte protoheme, characterized in that: the device comprises an analysis platform (1), a running track (2), a code scanning gun (3), a pushing fixing plate (4), a pushing fixing plate (5), a cuvette carrier assembly (6), a sample placing area (7), a disposable TIP head (8), a cuvette incubation detection assembly (9), a sample adding arm module (10), a pushing motion sensor (11), a pushing motion sensor (12) and a carrier optical coupler (13), wherein the running track (2) is arranged on the lower side above the analysis platform (1); the code scanning gun (3) is clamped on the running track (2); the propulsion fixing plate (4) is arranged at one end above the analysis platform (1); the pushing fixing plate (5) is arranged at one end, deviating from the pushing fixing plate (4), of the upper part of the analysis platform (1); the carrier optical couplers (13) are multiple, and the carrier optical couplers (13) are arranged on the inner sides of the pushing fixing plate (4) and the pushing fixing plate (5); the cuvette carrier assembly (6) is arranged between the pushing and fixing plates (4); the sample placing area (7) is arranged at the lower side between the pushing fixing plate (4) and the pushing fixing plate (5); the disposable TIP head (8) is arranged on the upper side between the pushing fixing plate (4) and the pushing fixing plate (5); the cuvette incubation detection assembly (9) is arranged on the upper side above the analysis platform (1); the sample adding arm module (10) is arranged above the analysis platform (1), and the sample adding arm module (10) is positioned between the disposable TIP head (8) and the push-out fixing plate (5); the propulsion motion sensor (11) is arranged on one side, close to the propulsion fixing plate (4), of the upper end of the analysis platform (1); the push-out motion sensor (12) is arranged on one side, close to the push-out fixing plate (5), of the upper end of the upper part of the analysis platform (1);
the cuvette carrier assembly (6) comprises a cuvette carrier (61), a cuvette holder (62) and a disposable cuvette (63), the cuvette carrier (61) being arranged between the advancing fixing plates (4); a plurality of colorimetric cup placing frames (62) are adopted, and the colorimetric cup placing frames (62) are arranged above the colorimetric cup carrier rack (61); the disposable colorimetric cups (63) are multiple, and the disposable colorimetric cups (63) are arranged on the side face of the cuvette placing frame (62).
2. The in-line biochemical analyzer for detecting protoheme of tissue cells according to claim 1, wherein: the cuvette incubation detection assembly (9) comprises a cuvette incubation detection plate (91), a detection module (92), a detection optocoupler (93), a reagent adding optocoupler (94) and a sample adding optocoupler (95), wherein the cuvette incubation detection plate (91) is arranged on the upper side above the analysis platform (1); the number of the detection modules (92) is multiple, and the detection modules (92) are arranged above the cuvette incubation detection plate (91); the detection optocoupler (93) is arranged at one end, close to the propulsion fixing plate (4), of the cuvette incubation detection plate (91); the sample adding photocoupler (95) is arranged in the middle of the cuvette incubation detection plate (91); add on reagent opto-coupler (94) and install on cuvette incubation pick-up plate (91), and add between reagent opto-coupler (94) and this opto-coupler of application of sample (95) and detection opto-coupler (93).
3. The in-line biochemical analyzer for detecting protoheme of tissue cells according to claim 1, wherein: the analysis platform is characterized by further comprising an electric control cabinet and a PLC (programmable logic controller), wherein the electric control cabinet is arranged below the analysis platform (1), is connected with a mains supply through a power line and is used for supplying power to the analyzer; the PLC is installed below the analysis platform (1) and connected with the electric control cabinet through a wire, and the PLC is used for controlling the analyzer.
4. The in-line biochemical analyzer for detecting protoheme of tissue cells according to claim 1, wherein: the code scanning gun (3) is connected with the running track (2) in a sliding mode, and the running track (2) is used for guiding and supporting the code scanning gun (3); the pushing fixing plate (4) and the pushing fixing plate (5) are symmetrically arranged; the sample placing area (7) is used for placing a sample; the disposable TIP head (8) is used for sucking reagent and sample; the sample adding arm module (10) is connected with the PLC and the electric control cabinet through wires respectively, and the sample adding arm module (10) is used for clamping the disposable TIP head (8) to move and perform needle removal operation.
5. The in-line biochemical analyzer for detecting protoheme of tissue cells according to claim 1, wherein: the propulsion motion sensor (11) is respectively connected with the PLC and the electric control cabinet through leads, and the propulsion motion sensor (11) is used for sensing the propulsion of the cuvette; the push-out motion sensor (12) is respectively connected with the PLC and the electric control cabinet through leads, and the push-out motion sensor (12) is used for sensing the push-out of the cuvette; and the carrier optical coupler (13) is respectively connected with the PLC and the electric control cabinet through wires.
6. The in-line biochemical analyzer for detecting protoheme of tissue cells according to claim 1, wherein: the cuvette carrier (61) is used for supporting a colorimetric cup placing frame (62) and a disposable colorimetric cup (63); the cuvette placing racks (62) are uniformly distributed above the cuvette carrier (61), and the cuvette placing racks (62) are used for installing disposable colorimetric cups (63); the number of the disposable colorimetric cups (63) is the same as that of the colorimetric cup placing frames (62).
7. The in-line biochemical analyzer for detecting tissue cell pro-heme according to claim 2, wherein: the detection module (92) is used for installing a detection optocoupler (93); the detection optocoupler (93) is respectively connected with the PLC and the electric control cabinet through wires, and the detection optocoupler (93) detects the colorimetric cups; the reagent adding optical coupler (94) is respectively connected with the PLC and the electric control cabinet through wires, and the reagent adding optical coupler (94) is used for sensing the action of a reagent; this opto-coupler of application of sample (95) links to each other with PLC controller and automatically controlled cabinet respectively through the wire, and this opto-coupler of application of sample (95) is used for the response to add the sample action.
8. A use method of a flow line type biochemical analyzer for detecting protoheme of tissue cells is characterized in that: the use method of the assembly line type biochemical analyzer for detecting the protoheme of the tissue cells comprises the following steps:
step S101: preparing for instrument detection, and checking whether the reagent bottle is sufficient; placing a sample carrier on which a sample is placed in advance in a sample placing area (7); the code scanning gun (3) records the sample carrier number and the sample bar code; placing a cuvette placing rack (62) in which a disposable cuvette (63) is placed in advance on a cuvette carrier (61); the left side of the cuvette carrier assembly (6) is buckled with a protruding flanging of the positioning baffle, and a lower groove is buckled with a triangular shifting sheet on the table top; the code scanning gun (3) records the number of the cuvette carrier;
step S102: the cuvette is pushed forward, the cuvette pushing mechanism is pushed forward, the carriage optocoupler (13) at the position of the fixed plate (4) is pushed to display green when the cuvette carriage assembly (6) exists, the carriage optocoupler (13) at the position of the fixed plate (4) is pushed to display red when the cuvette carriage assembly (6) does not exist, the cuvette carriage assembly (6) is pushed until a region to be measured, and the forward pushing is stopped at the moment;
step S103: detecting a cuvette, starting rightward propulsion, reading the blank of a disposable colorimetric cup (63) by a detection unit when the cuvette carrier assembly (6) completely enters a cuvette incubation detection assembly (9), sensing to start reagent filling at a reagent filling position, finishing reagent filling, enabling a corresponding reagent filling optical coupler (94) to be red at the moment, restarting a propulsion mechanism on the left side of the disposable colorimetric cup (63) to propel a subsequent cuvette carrier assembly (6) to enter a region to be detected, and circularly moving; simultaneously, after the reagent is added, the cuvette carrier assembly (6) moves to a sample filling sensor, the sample filling arm module (10) starts to suck the suction head and the sample, the next one-time color cup (63) position waits for conveying the one-time color cup (63) for sample filling, the one-time TIP head (8) sucks the sample back and uniformly mixes the sample after the sample filling, then the needle is removed, the suction head and the sample are sucked, and the process is repeated;
step S104: and (3) after the cuvette is pushed out and the result is read, the cuvette carrier assembly (6) moves to a push-out area and is sensed by a push-out motion sensor (12) to reciprocate back and forth to push out the cuvette carrier assembly (6), the carriage optocoupler (13) at the position of the fixed plate (5) is pushed out to display red when the cuvette carrier assembly (6) exists, the carriage optocoupler (13) at the position of the fixed plate (5) is pushed out to display green when the cuvette carrier assembly (6) does not exist, and finally the cuvette carrier assembly (6) can be continuously used after the disposable colorimetric cups (63) are processed after being taken out manually.
CN202111416348.5A 2021-11-25 2021-11-25 A pipelined biochemical analysis appearance for detecting protoheme of histocyte Pending CN114184801A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116930168A (en) * 2023-07-21 2023-10-24 上海品峰医疗科技有限公司 Pigment stock solution recycling constant volume device and method

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116930168A (en) * 2023-07-21 2023-10-24 上海品峰医疗科技有限公司 Pigment stock solution recycling constant volume device and method
CN116930168B (en) * 2023-07-21 2024-04-02 上海品峰医疗科技有限公司 Pigment stock solution recycling constant volume device and method

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