CN114177130B

CN114177130B - External preparation for myofascitis and preparation method and application thereof

Info

Publication number: CN114177130B
Application number: CN202111566219.4A
Authority: CN
Inventors: 李叙诺; 郑扬航; 郑嘉容; 李秀飞; 陈雪琴
Original assignee: Individual
Current assignee: Individual
Priority date: 2021-12-20
Filing date: 2021-12-20
Publication date: 2023-09-29
Anticipated expiration: 2041-12-20
Also published as: CN114177130A

Abstract

The invention provides an external preparation for myofascitis and a preparation method and application thereof, and relates to the technical field of traditional Chinese medicines. The external preparation for myofascitis is mainly prepared from ginger, curcuma aromatica, geranium, henna, blood circulation activating pill, common head kidney, radix stemonae, drynaria rhizome, liquorice, ground beetle, nux vomica, frankincense and peppermint according to a specific proportion, and the components in the external preparation are matched with each other and promoted mutually, so that the external preparation can effectively treat myofascitis, has remarkable effect, is safe and free from toxic and side effects, does not relapse, is convenient to use, and has low cost, and the health problems of body distending pain, muscle numbness, dyskinesia and the like caused by the myofascitis are solved. The preparation method of the external preparation for myofascitis provided by the invention is characterized in that the raw materials are leached, the active ingredients obtained by leaching are high, and the active ingredients are well fused, and the method is simple and easy to implement.

Description

External preparation for myofascitis and preparation method and application thereof

Technical Field

The invention relates to the technical field of traditional Chinese medicines, in particular to an external preparation for myofascitis and a preparation method and application thereof.

Background

Myofascitis refers to the aseptic inflammatory response of muscle and fascia. When the body is subjected to traumatic injury, overfatigue and cold climate environment of the body, the body is subjected to wind-cold invasion, and acute onset of myofascitis induced by bad exogenous factors such as improper sleeping posture and position, the disease usually occurs to muscles and ligaments of the neck, shoulder, back or waist and back, and acute or chronic injuries, strain and the like of joint capsules of limbs; the main characteristics are diffuse pain with repeated attacks of acute or chronic, skin numbness, dyskinesia, spasm, coolness and the like, pain and discomfort aggravated at night, and pain caused by cold weather and depressed mood. Patients with myofascitis often have difficulty in concentrating on study and work due to pain in the neck, waist and the like, and a part of people even cause psychological problems such as anxiety, depression and the like; along with the progress of the disease and the extension of the disease course, fasciitis can affect adjacent muscles, accelerate degeneration of cervical and lumbar facet joints and intervertebral discs, thereby causing diseases such as cervical spondylosis, lumbar disc herniation, lumbar spinal stenosis, lumbar spondylolisthesis and the like, increasing pain of patients and seriously affecting the heart and body health and life quality of the patients. The clinic treatment method for myofascitis is more, and the traditional common methods include massage, cupping, scraping, acupuncture, physiotherapy, needle knife and the like, and the traditional method has long treatment time and slow effect.

Therefore, it is necessary to develop a Chinese herbal medicine external preparation which has obvious curative effect on myofascitis and is simple to use, has no side effect on human body, and has wide market prospect.

In view of this, the present invention has been made.

Disclosure of Invention

A first object of the present invention is to provide an external preparation for myofascitis to solve at least one of the above problems.

The second aim of the invention is to provide a preparation method of the external preparation for myofascitis, which is simple and easy to implement, has high effective components obtained by leaching, and ensures that the effective components are fully fused.

A third object of the present invention is to provide an application of the external preparation for myofascitis in preparing a medicament for treating myofascitis.

In a first aspect, the invention provides an external preparation for myofascitis, which is mainly prepared from the following raw materials in parts by mass: 48-88 parts of ginger, 48-88 parts of curcuma wenyujin, 48-88 parts of geranium, 48-88 parts of henna, 48-88 parts of blood circulation activating pill, 48-88 parts of kidney of vegetable head, 31-65 parts of radix stemonae, 31-63 parts of drynaria, 31-63 parts of liquorice, 31-63 parts of ground beetle, 13-31 parts of nux vomica, 13-31 parts of frankincense and 13-31 parts of peppermint.

The preparation method is characterized by mainly comprising the following raw materials in parts by mass: 58-78 parts of ginger, 58-78 parts of curcuma aromatica, 58-78 parts of geranium, 58-78 parts of henna, 58-78 parts of red lead for promoting blood circulation, 58-78 parts of kidney of vegetable head, 41-55 parts of radix stemonae, 41-53 parts of drynaria rhizome, 41-53 parts of liquorice, 41-53 parts of ground beetle, 18-26 parts of nux vomica, 18-26 parts of frankincense and 18-26 parts of peppermint.

The preparation method is characterized by mainly comprising the following raw materials in parts by mass: 64 to 72 parts of ginger, 64 to 72 parts of curcuma aromatica, 64 to 72 parts of geranium, 64 to 72 parts of henna, 64 to 72 parts of red lead for promoting blood circulation, 64 to 72 parts of kidney of vegetable head, 44 to 52 parts of radix stemonae, 44 to 50 parts of drynaria rhizome, 44 to 50 parts of liquorice, 44 to 50 parts of ground beetle, 20 to 24 parts of nux vomica, 20 to 24 parts of frankincense and 20 to 24 parts of peppermint.

As a further technical scheme, the myofascitis external preparation also comprises auxiliary materials;

preferably, the adjuvant comprises ethanol.

In a second aspect, the invention provides a preparation method of the external preparation for myofascitis, wherein the raw materials are extracted, and the extracted liquid is extracted to prepare the external preparation for myofascitis.

As a further technical scheme, the leaching comprises ethanol leaching;

preferably, the mass concentration of the ethanol is 90% -100%, preferably 95%.

As a further technical scheme, the mass ratio of the raw materials to the ethanol is (451-875): (1620 to 3240), preferably (553 to 775): (2020-2840).

As a further technical scheme, the leaching is sealed leaching;

preferably, the leaching time is 7-15 days;

preferably, during the leaching process, stirring is carried out 1 to 2 times per day.

As a further technical solution, the raw material is crushed before the leaching.

As a further technical solution, the leaching solution is filtered after the leaching.

In a third aspect, the invention provides an application of an external preparation for myofascitis in preparing a medicament for treating myofascitis.

Compared with the prior art, the invention has the following beneficial effects:

the external preparation for myofascitis is mainly prepared from ginger, curcuma aromatica, geranium, henna, blood circulation activating pill, common head kidney, radix stemonae, drynaria rhizome, liquorice, ground beetle, nux vomica, frankincense and peppermint according to a specific proportion, and the components in the external preparation are matched with each other and promoted mutually, so that the external preparation can effectively treat myofascitis, has remarkable effect, is safe and free from toxic and side effects, does not relapse, is convenient to use, and has low cost, and the health problems of body distending pain, muscle numbness, dyskinesia and the like caused by the myofascitis are solved.

The preparation method of the external preparation for myofascitis provided by the invention is characterized in that the raw materials are leached, the active ingredients obtained by leaching are high, and the active ingredients are well fused, and the method is simple and easy to implement.

The external preparation for myofascitis has the myofascitis treatment effect, and can be used for preparing medicines for treating myofascitis.

Detailed Description

Embodiments of the present invention will be described in detail below with reference to embodiments and examples, but it will be understood by those skilled in the art that the following embodiments and examples are only for illustrating the present invention and should not be construed as limiting the scope of the present invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention. The specific conditions are not specified, and the process is carried out according to conventional conditions or conditions suggested by manufacturers. The reagents or apparatus used were conventional products commercially available without the manufacturer's attention.

Wherein, ginger is recorded in Chinese pharmacopoeia: the product is fresh rhizome of ginger belonging to the family Zingiberaceae. [ MEANS FOR SOLVING PROBLEMS ] pungent and slightly warm. [ Gui Jing ] enters lung, spleen and stomach meridians. [ functional indications ] relieve exterior syndrome, dispel cold, warm middle energizer, arrest vomiting, resolve phlegm and relieve cough. Can be used for treating common cold due to wind-cold, emesis due to stomach cold, and cough due to cold phlegm. The invention takes ginger as a raw material to prepare the external preparation for myofascitis, wherein the typical but non-limiting weight parts of ginger are 48 parts, 58 parts, 68 parts, 78 parts or 88 parts.

Curcuma wenyujin is recorded in Chinese pharmacopoeia: the product is a dried root tuber of Curcuma wenyujin Y.H.Chen et C.Ling of Zingiberaceae. [ MEANS FOR SOLVING PROBLEMS ] pungent, bitter and cold. [ Gui Jing ] enters liver, heart and lung meridians. [ Functions ] move qi and remove blood stasis, clear heart and resolve stagnation, promote bile flow and alleviate jaundice. Can be used for treating amenorrhea, dysmenorrhea, chest and abdominal distention, tingling, fever, coma, epilepsy, and jaundice and dark urine. The invention takes curcuma aromatica as a raw material to prepare the external preparation for myofascitis, wherein the curcuma aromatica is typically but not limited to 48 parts, 58 parts, 68 parts, 78 parts or 88 parts by weight.

Geranium wilfordii according to the description of Chinese herbal medicine assembly: [ Source ] dried fruit-bearing aerial parts of Erodium meyerianum. [ the nature ] is bitter, pungent and flat. [ Gui Jing ] enters liver, kidney and large intestine meridians. [ Functive indications ] dispel wind-dampness. Can be used for treating rheumatalgia. Pharmacological action: herba Erodii seu Geranii has effects of dispelling pathogenic wind, promoting blood circulation and inhibiting bacteria; the traditional Chinese medicine composition has the effects of activating blood vessels and dredging collaterals, and is often applied to symptoms such as rheumatalgia, rheumatic paralysis, limb numbness, traumatic injury and the like; has inhibiting effect on various germs. The invention takes geranium wilfordii as raw material to prepare external preparation for myofascitis, and the typical but non-limiting weight parts of geranium wilfordii are 48 parts, 58 parts, 68 parts, 78 parts or 88 parts.

Henna leaf according to the description of Chinese Ben Cao: [ Source ] is the leaf of Lawsonia inermis of Lythraceae; [ Guijing ] heart meridian; [ Functive indications ] convergence, hemostasis; bleeding from major wounds. The external preparation for myofascitis is prepared from henna, which is typically but not limited to 48 parts, 58 parts, 68 parts, 78 parts or 88 parts by weight.

Blood circulation activating pill according to the description of Chinese Ben Cao: [ Source ] is the whole herb of Labiatae plant blood-activating pill. [ sexually ] bitter; octyl; it is cool in nature. [ Guijing ] liver; a bladder; the bladder meridian. [ functional indications ] diuresis and stranguria-treating; clearing heat and detoxicating; disperse blood stasis and detumescence. Mainly treating stranguria caused by heat and stone stranguria; jaundice due to damp-heat; sore, carbuncle and swelling; traumatic injury. Pharmacological action: has the effects of promoting bile flow, promoting urination, dissolving calculus and inhibiting bacteria; can promote bile secretion of liver cells, increase bile in liver bile duct, increase internal pressure, and discharge bile. The external preparation for myofascitis is prepared from the blood-activating pills, wherein the typical but non-limiting weight parts of the blood-activating pills are 48 parts, 58 parts, 68 parts, 78 parts or 88 parts.

The kidney of the cabbage is recorded in the Chinese herbal medicine assembly: [ Source ] Kidney of the genus Kidney of the family Acanthaceae, root, stem and leaf are used as the medicine. [ the nature ] is slightly sweet and cool. [ functional indications ] root: nourishing yin and tonifying kidney. Can be used for treating lumbago due to kidney deficiency, toothache due to yin deficiency, persistent or chronic hepatitis, nephritis or nephropyelitis. Stems and leaves: clear away heat and toxic materials. For acute infectious hepatitis; it is indicated for furuncle, sprain of tendons. The invention takes the cauliflower kidney as the raw material to prepare the external preparation for myofascitis, and the representative but non-limiting weight parts of the cauliflower kidney are 48 parts, 58 parts, 68 parts, 78 parts or 88 parts.

Stemonae radix according to the description of Chinese pharmacopoeia: the product is a dried root tuber of Stemona sessilifolia (Bunge.) Hsiao, stemona tenuifolia (Bunge.) Hsiao, stemona japonica (Stemona japonica) Hsiao, stemona tuberosa (Stemona japonica) Hsiao, stemona japonica (Stemona tuberosa (Stemona japonica) Hsiao, stemona japonica (. [ the nature ] sweet, bitter and slightly warm. [ Gui Jing ] enters lung meridian. [ functional indications ] moisten lung, descend qi, relieve cough, kill parasites. Can be used for treating cough due to new and old times, tuberculosis cough, and pertussis; is externally applied to head lice, body lice, enterobiasis and pruritus vulvae. Radix stemonae with lung moistening and cough relieving effects; is used for treating cough due to yin deficiency. The invention takes stemona root as a raw material to prepare the external preparation for myofascitis, wherein the typical but non-limiting weight parts of stemona root are 31 parts, 35 parts, 40 parts, 45 parts, 50 parts, 55 parts, 60 parts or 65 parts.

Rhizoma drynariae is recorded in Chinese pharmacopoeia: the product is the dried rhizome of drynaria fortunei which is a plant of the genus Dryopteris. [ the nature ] is bitter and warm. [ Gui Jing ] enters kidney and liver meridians. [ functional indications ] Kidney-tonifying and bone-strengthening, pain-relieving, wound-continuing and pain-relieving. Can be used for treating lumbago due to kidney deficiency, tinnitus, deafness, odontoseisis, traumatic injury, contusion, and tendons and bones injury; it is used for treating alopecia areata and vitiligo. The invention takes drynaria rhizome as a raw material to prepare the external preparation for myofascitis, wherein the typical but non-limiting weight parts of the drynaria rhizome are 31 parts, 35 parts, 40 parts, 45 parts, 50 parts, 55 parts, 60 parts or 63 parts.

Licorice root, recorded in Chinese pharmacopoeia: the product is a dry root of Glycyrrhiza uralensis Fisch.L.of Leguminosae, glycyrrhiza uralensis Fisch.L.or Glycyrrhiza glabra Linne. Sweet and flat. [ Gui Jing ] it is returned to heart, lung, spleen and stomach meridians. [ functional indications ] the medicine has the functions of invigorating spleen, replenishing qi, clearing away heat and toxic material, eliminating phlegm, relieving cough, relieving spasm and pain and regulating the medicines. Can be used for treating weakness of spleen and stomach, listlessness, debilitation, palpitation, short breath, cough with excessive phlegm, abdominal pain, limb spasm, carbuncle, swelling, sore and toxic materials, and relieving drug toxicity and intensity. The invention takes liquorice as raw material to prepare external preparations for myofascitis, and the typical but non-limiting weight parts of liquorice are 31 parts, 35 parts, 40 parts, 45 parts, 50 parts, 55 parts, 60 parts or 63 parts.

Ground beetle is recorded in Chinese pharmacopoeia: the product is dried female body of Eupolyphaga Seu Steleophaga or Eupolyphaga Seu Steleophaga of Eupolyphaga Seu Steleophaga. Salty and cold; it is slightly toxic. [ Gui Jing ] enters liver meridian. [ Functions ] break blood stasis and strengthen tendons and bones. Can be used for treating fracture injury, amenorrhea due to blood stasis, and abdominal mass. The invention takes ground beetle as a raw material to prepare the external preparation for myofascitis, and the typical but non-limiting weight parts of ground beetle are 31 parts, 35 parts, 40 parts, 45 parts, 50 parts, 55 parts, 60 parts or 63 parts.

Nux vomica is recorded according to Chinese pharmacopoeia: [ Source ] this product is a dried mature seed of the plant Strychnos nux-vomica belonging to the family Strychnaceae. [ sexually ] bitter, warm; it is toxic. [ Gui Jing ] enters liver and spleen meridians. [ functional indications ] the composition has the effects of dredging collaterals, relieving pain, resolving masses and detumescence. Can be used for treating rheumatism, numbness, paralysis, traumatic injury, carbuncle, and swelling and pain; infantile paralysis sequelae, rheumatoid arthralgia. The invention takes nux vomica as raw material to prepare external preparation for myofascitis, and the typical but non-limiting weight parts of nux vomica are 13 parts, 15 parts, 20 parts, 25 parts, 30 parts or 31 parts.

Olibanum is recorded in the dictionary of Chinese medicine Dazhui: [ Source ] is a gum resin of the olive family plant Boswellia carterii. [ MEANS FOR SOLVING PROBLEMS ] A pungent and bitter taste and warm taste. [ Gui Jing ] enters heart, liver and spleen meridians. [ functional indications ] regulate qi, activate blood, relieve pain, and dispel toxins. For stagnation of qi and blood, pain in heart and abdomen, carbuncle, sore, swelling and toxicity, traumatic injury, dysmenorrhea, postpartum blood stasis and stinging. The invention takes olibanum as raw material to prepare external preparation for myofascitis, wherein the typical but non-limiting weight parts of olibanum are 13 parts, 15 parts, 20 parts, 25 parts, 30 parts or 31 parts.

Peppermint, according to the records of the Chinese pharmacopoeia: the product is a dry aerial part of peppermint belonging to the genus Mentha of the family Labiatae. [ the nature ] is pungent and cool. [ Gui Jing ] enters lung and liver meridians. [ Functive indications ] disperse wind-heat. Clear head and eyes, promote eruption. Can be used for treating wind-heat type common cold, initial wind-warm syndrome, headache, conjunctival congestion, pharyngitis, aphtha, rubella, measles, chest distress and hypochondrium distention. The invention takes peppermint as raw material to prepare external preparations for myofascitis, wherein the typical but non-limiting weight parts of peppermint are 13 parts, 15 parts, 20 parts, 25 parts, 30 parts or 31 parts.

In some preferred embodiments, the composition is prepared from the following raw materials in parts by mass: 58-78 parts of ginger, 58-78 parts of curcuma aromatica, 58-78 parts of geranium, 58-78 parts of henna, 58-78 parts of red lead for promoting blood circulation, 58-78 parts of kidney of vegetable head, 41-55 parts of radix stemonae, 41-53 parts of drynaria rhizome, 41-53 parts of liquorice, 41-53 parts of ground beetle, 18-26 parts of nux vomica, 18-26 parts of frankincense and 18-26 parts of peppermint.

In some preferred embodiments, the composition is prepared from the following raw materials in parts by mass: 64 to 72 parts of ginger, 64 to 72 parts of curcuma aromatica, 64 to 72 parts of geranium, 64 to 72 parts of henna, 64 to 72 parts of red lead for promoting blood circulation, 64 to 72 parts of kidney of vegetable head, 44 to 52 parts of radix stemonae, 44 to 50 parts of drynaria rhizome, 44 to 50 parts of liquorice, 44 to 50 parts of ground beetle, 20 to 24 parts of nux vomica, 20 to 24 parts of frankincense and 20 to 24 parts of peppermint.

The external preparation for myofascitis has better effect of treating myofascitis by further optimizing and adjusting the proportion of each raw material in the external preparation for myofascitis.

In some preferred embodiments, the external preparation for myofascitis further includes an adjuvant, and the adjuvant is not particularly limited in the present invention, and the adjuvant known in the art may be used.

Preferably, the auxiliary material comprises ethanol, and the ethanol has good solubility for the effective components, so that the effective substances can be fully fused.

In some preferred embodiments, the leaching comprises ethanol leaching; the ethanol has high solubility on the effective components in the medicine, and is favorable for extracting small components in the medicine.

Preferably, the mass concentration of the ethanol may be, for example, but not limited to, 90%, 92%, 94%, 96%, 98% or 100%, preferably 95%.

The ethanol with the concentration range is adopted for leaching, so that the extraction effect of the active ingredients in the raw materials is good.

In some preferred embodiments, the mass ratio of the feedstock to ethanol may be, for example, but not limited to 451:3240, 553:2840, 660:2420, 775:2020, or 875:1620, preferably (553-775): (2020-2840).

The ethanol with the proportion is adopted to leach the raw materials, and the full leaching of the effective components in the raw materials is realized on the premise of reducing the ethanol consumption.

In some preferred embodiments, the leaching is sealed leaching, and sealed leaching is used to avoid volatilization of the leaching solvent and improve leaching quality.

Preferably, the time of the leaching may be, for example, but not limited to, 7 days, 9 days, 11 days, 13 days, or 15 days.

In the invention, the extraction efficiency of the effective components in the raw materials is improved through further optimization and adjustment of the extraction operation.

In some preferred embodiments, the raw materials are crushed before the leaching, and the raw materials are crushed, so that the extraction efficiency of the effective components in the raw materials is improved, and the extraction time is shortened.

In some preferred embodiments, the leaching solution is filtered after the leaching. The extract from the leaching may contain some insoluble impurities which may be removed by filtration in order to increase the concentration of the extract.

The invention is further illustrated by the following specific examples and comparative examples, however, it should be understood that these examples are for the purpose of illustration only in greater detail and should not be construed as limiting the invention in any way.

Example 1

An external preparation for myofascitis is prepared from the following raw materials: 88 parts of ginger, 48 parts of curcuma aromatica, 88 parts of geranium, 48 parts of henna, 88 parts of blood-activating pellet, 48 parts of vegetable head and kidney, 65 parts of radix stemonae, 31 parts of drynaria rhizome, 63 parts of liquorice, 31 parts of ground beetle, 31 parts of nux vomica, 13 parts of frankincense and 31 parts of peppermint.

The preparation method comprises the following steps:

pulverizing the raw materials, leaching with 90% ethanol for 15 days, stirring for 1-2 times a day, wherein the mass ratio of the raw materials to the ethanol is 673:3240, performing rough filtration to obtain filtrate after leaching, squeezing residues obtained by rough filtration to obtain residual liquid, mixing the filtrate with the residual liquid to obtain mixed liquor, and performing fine filtration to obtain fine filtrate, wherein the fine filtrate is the myofascitis external preparation.

Example 2

An external preparation for myofascitis is prepared from the following raw materials: 48 parts of ginger, 88 parts of curcuma wenyujin, 48 parts of geranium, 88 parts of henna, 48 parts of blood-activating pellet, 88 parts of vegetable head and kidney, 31 parts of radix stemonae, 63 parts of drynaria rhizome, 31 parts of liquorice, 63 parts of ground beetle, 13 parts of nux vomica, 31 parts of frankincense and 13 parts of peppermint.

The preparation method comprises the following steps:

crushing the raw materials, leaching the raw materials with 92% ethanol for 13 days, stirring the raw materials and the ethanol for 1 to 2 times every day, wherein the mass ratio of the raw materials to the ethanol is 653:2840, performing rough filtration to obtain filtrate after leaching, squeezing dregs obtained by rough filtration to obtain residual liquid, mixing the filtrate with the residual liquid to obtain mixed liquor, and performing fine filtration on the mixed liquor to obtain fine filtrate, wherein the fine filtrate is the myofascitis external preparation.

Example 3

An external preparation for myofascitis is prepared from the following raw materials: 78 parts of ginger, 58 parts of curcuma aromatica, 78 parts of geranium, 58 parts of henna, 78 parts of blood-activating pellet, 58 parts of vegetable head and kidney, 55 parts of radix stemonae, 41 parts of drynaria rhizome, 53 parts of liquorice, 41 parts of ground beetle, 26 parts of nux vomica, 18 parts of frankincense and 26 parts of peppermint.

The preparation method comprises the following steps:

pulverizing the raw materials, leaching with 94% ethanol for 11 days, stirring for 1-2 times a day, wherein the mass ratio of the raw materials to the ethanol is 668:2420, performing rough filtration to obtain filtrate after leaching, squeezing residues obtained by rough filtration to obtain residual liquid, mixing the filtrate with the residual liquid to obtain mixed liquor, and performing fine filtration to obtain fine filtrate, wherein the fine filtrate is the myofascitis external preparation.

Example 4

An external preparation for myofascitis is prepared from the following raw materials: 58 parts of ginger, 78 parts of curcuma aromatica, 58 parts of geranium, 78 parts of henna, 58 parts of blood circulation promoting pill, 78 parts of vegetable head and kidney, 41 parts of radix stemonae, 53 parts of rhizoma drynariae, 41 parts of liquorice, 53 parts of ground beetle, 18 parts of nux vomica, 26 parts of frankincense and 18 parts of peppermint.

The preparation method comprises the following steps:

crushing the raw materials, leaching the raw materials with ethanol with the mass concentration of 95% for 9 days, stirring the raw materials and the ethanol for 1 to 2 times every day, wherein the mass ratio of the raw materials to the ethanol is 658:2020, performing rough filtration to obtain filtrate after the leaching is finished, squeezing dregs obtained by the rough filtration to obtain residual liquid, mixing the filtrate with the residual liquid to obtain mixed liquor, and performing fine filtration on the mixed liquor to obtain fine filtrate, wherein the fine filtrate is the myofascitis external preparation.

Example 5

An external preparation for myofascitis is prepared from the following raw materials: 68 parts of ginger, 68 parts of curcuma aromatica, 68 parts of geranium, 68 parts of henna, 68 parts of blood circulation promoting pill, 68 parts of vegetable head and kidney, 48 parts of radix stemonae, 47 parts of rhizoma drynariae, 47 parts of liquorice, 47 parts of ground beetle, 22 parts of nux vomica, 22 parts of frankincense and 22 parts of peppermint.

The preparation method comprises the following steps:

crushing the raw materials, leaching the raw materials with ethanol with the mass concentration of 98% for 7 days, stirring the raw materials and the ethanol for 1 to 2 times per day, wherein the mass ratio of the raw materials to the ethanol is 663:1620, performing rough filtration to obtain filtrate after the leaching is finished, squeezing dregs obtained by the rough filtration to obtain residual liquid, mixing the filtrate with the residual liquid to obtain mixed liquor, and performing fine filtration on the mixed liquor to obtain fine filtrate, wherein the fine filtrate is the myofascitis external preparation.

Case 1

Bao Mou A, 55 years old, live in Qingqing city of Winking, zhejiang, and the right elbow, because of the frequent sports, brings the table tennis, causes biceps muscle fasciitis, biceps tendon pain tolerance, is not improved for more than 5 years after various orthopedics treatments in Winzhou hospitals, still can not be cured by acupuncture, massage and Yongjia, and peaceful folk name Chinese medicine plaster treatment, and also causes skin ulcer, trouble and palpitation; the preparation of the embodiment 1 of the invention is used for the first time from 15:10 PM on 9 months 5 months 2017, pain is relieved after 15 minutes of application, joints are flexible, the preparation of the embodiment 1 of the invention is applied for the second time about 10:30 PM on 6 months 9, and after half an hour, the elbow joint is recovered as usual and no recurrence exists in 4 years so far. The biceps tendon pain problem was eliminated from this for more than 5 years.

Case 2

Chen Mou when a female, 51 years old, live in a new Huhaide garden of Leqing city in the Zhejiang province, the right shoulder has myofascitis for 3 years, the right shoulder is frequently painful and aggravated at night, sometimes wakes up at midnight due to pain, sometimes cannot sleep due to pain, is weak to lift hands, cannot dry and live, and seriously affects life; once the doctor is attached to the first hospital of the medical college in Wenzhou, the doctor is seen by the expert, the doctor is not improved, and the doctor is always massaged, acupuncture and moxibustion, moxibustion and pain starts in the next day although the doctor is relieved after the doctor is just treated, and the doctor is not cured; the preparation of the invention of the example 2 is firstly used in the period of 10 days 8 and 2021, the pain of the shoulder is relieved after 10 minutes of application, the preparation of the invention is applied again after 15 minutes, the pain of the shoulder is eliminated after 30 minutes, the shoulder is heated, the hands are lifted forcefully, the extension is free, the shoulder joint is recovered as usual, and no recurrence is seen for more than 120 days nowadays.

Case 3

Zheng Mou when female, 55 years old, live in Qingjiuzhi city of the Windqing city of the Zhejiang province, the right finger has myofascitis for more than 4 years, the right finger has numbness and stiffness, can not make a fist, and has weak fingers, and the user has tingling and swelling feeling and pain when using the finger, can not be dried and alive, and seriously affects life; three doctors in Liuzhi have seen expert doctors, do not see improvement, do acupuncture and moxibustion, and do not see effect; the preparation of the embodiment 3 of the invention is firstly used after 10 am on 8 months and 14 am in 2021, and is smeared on the flexor digitorum and the superficial flexor digitorum for 15 minutes, the palm and the arm are heated, the fingers can already grip the fist, the tingling pain is lost, the fist is forcefully gripped by the middle finger of the right hand in about 11:30, and the single finger is freely stretched, is recovered as usual and has no recurrence after more than 120 days.

Case 4

Female with holes is 67 years old, living in Qingqing city of the Winking state of Zhejiang, and has the lumbar myofascitis for more than 2 years, bending over the waist, being unable to stand, supporting the waist with one hand and suffering from full face; when the patient is ill, the patient can not stand and walk, two persons are required to walk, the patient is helped to go through the treatment of Shanghai trimethyl hospital, the treatment of Leqing people's hospital, leqing Zhongzhu and other doctors, the treatment is not improved all the time, about 10 am in 9 month 10 in 2016, the preparation of the invention is used for the first time, after 15 minutes of application, the waist is heated, the patient stands up from the stool for a few steps, and then bends down to feel relaxed and free, so that a plurality of yoga actions are successively performed, the patient is soft and normal, and no recurrence is seen for more than 5 years now.

Case 5

Zhang Mou the men, 53 years old, live in the urban south street Dan Macun of Qing City, zhejiang, the left foot knee joint has myofascitis for more than 5 years, because of a car accident before 5 years, the left foot knee joint is damaged, the left leg is shorter than the right leg by 5CM, the muscle is stiff, the left foot knee joint is painful, the rain or the weather becomes more painful when cold, people lean on the crutch when coming to stand, the people go through the domestic hospitals such as the Shanghai, beijing and the like, 10 ten thousands of years are spent, but the improvement is not seen, the knee joint feel fever is felt after the application for 15 minutes, the crutch is put down, 100 steps can be independently carried out, the crutch is 15:30 in the afternoon, zhang Mouyi people independently walk up and down stairs, the courtyard is jogged for 5 minutes, the left foot joint function is recovered, the problem of myofascitis of the left foot joint is not required to recur, and the problem of the myofascitis of the left foot joint of 5 years is solved from now.

Finally, it should be noted that: the above embodiments are only for illustrating the technical solution of the present invention, and not for limiting the same; although the invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some or all of the technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit of the invention.

Claims

1. The external preparation for myofascitis is characterized by being prepared from the following raw materials in parts by mass: 48-88 parts of ginger, 48-88 parts of curcuma wenyujin, 48-88 parts of geranium, 48-88 parts of henna, 48-88 parts of blood circulation activating pill, 48-88 parts of kidney of vegetable head, 31-65 parts of radix stemonae, 31-63 parts of drynaria, 31-63 parts of liquorice, 31-63 parts of ground beetle, 13-31 parts of nux vomica, 13-31 parts of frankincense and 13-31 parts of peppermint.

2. The external preparation for myofascitis according to claim 1, which is prepared from the following raw materials in parts by mass: 58-78 parts of ginger, 58-78 parts of curcuma aromatica, 58-78 parts of geranium, 58-78 parts of henna, 58-78 parts of red lead for promoting blood circulation, 58-78 parts of kidney of vegetable head, 41-55 parts of radix stemonae, 41-53 parts of drynaria rhizome, 41-53 parts of liquorice, 41-53 parts of ground beetle, 18-26 parts of nux vomica, 18-26 parts of frankincense and 18-26 parts of peppermint.

3. The external preparation for myofascitis according to claim 2, which is prepared from the following raw materials in parts by mass: 64 to 72 parts of ginger, 64 to 72 parts of curcuma aromatica, 64 to 72 parts of geranium, 64 to 72 parts of henna, 64 to 72 parts of red lead for promoting blood circulation, 64 to 72 parts of kidney of vegetable head, 44 to 52 parts of radix stemonae, 44 to 50 parts of drynaria rhizome, 44 to 50 parts of liquorice, 44 to 50 parts of ground beetle, 20 to 24 parts of nux vomica, 20 to 24 parts of frankincense and 20 to 24 parts of peppermint.

4. The external preparation for myofascitis according to claim 1, wherein the external preparation for myofascitis further comprises an auxiliary material;

the auxiliary material comprises ethanol.

5. The method for producing an external preparation for myofascitis according to any one of claims 1 to 4, wherein the raw material is extracted and the extracted solution is extracted to produce an external preparation for myofascitis.

6. The method of preparation of claim 5, wherein the leaching comprises ethanol leaching;

the mass concentration of the ethanol is 90-100%,

7. the method according to claim 6, wherein the mass concentration of ethanol is 95%.

8. The method according to claim 6, wherein the mass ratio of the raw materials to ethanol is (451 to 875): (1620 to 3240).

9. The method according to claim 8, wherein the mass ratio of the raw materials to ethanol is (553 to 775): (2020-2840).

10. The method of preparation of claim 5, wherein the leaching is sealed leaching;

the leaching time is 7-15 days;

in the leaching process, stirring is carried out for 1-2 times a day.

11. The method of claim 5, wherein the raw materials are crushed prior to leaching;

the leaching solution is filtered after the leaching.

12. Use of the external preparation for myofascitis according to any one of claims 1 to 4 or the external preparation for myofascitis prepared by the preparation method according to any one of claims 5 to 11 in the preparation of a medicament for treating myofascitis.