CN114150442A - Garlicin-loaded antibacterial packaging film and preparation method thereof - Google Patents
Garlicin-loaded antibacterial packaging film and preparation method thereof Download PDFInfo
- Publication number
- CN114150442A CN114150442A CN202111499519.5A CN202111499519A CN114150442A CN 114150442 A CN114150442 A CN 114150442A CN 202111499519 A CN202111499519 A CN 202111499519A CN 114150442 A CN114150442 A CN 114150442A
- Authority
- CN
- China
- Prior art keywords
- pvp
- pvb
- allicin
- packaging film
- antibacterial
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 20
- 229920006280 packaging film Polymers 0.000 title claims abstract description 14
- 239000012785 packaging film Substances 0.000 title claims abstract description 14
- 238000002360 preparation method Methods 0.000 title abstract description 9
- JDLKFOPOAOFWQN-VIFPVBQESA-N Allicin Natural products C=CCS[S@](=O)CC=C JDLKFOPOAOFWQN-VIFPVBQESA-N 0.000 claims abstract description 20
- JDLKFOPOAOFWQN-UHFFFAOYSA-N allicin Chemical compound C=CCSS(=O)CC=C JDLKFOPOAOFWQN-UHFFFAOYSA-N 0.000 claims abstract description 20
- 235000010081 allicin Nutrition 0.000 claims abstract description 20
- 229920000642 polymer Polymers 0.000 claims abstract description 10
- 239000003242 anti bacterial agent Substances 0.000 claims abstract description 8
- 230000000845 anti-microbial effect Effects 0.000 claims abstract description 3
- 239000000243 solution Substances 0.000 claims description 26
- 238000003756 stirring Methods 0.000 claims description 14
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 11
- 238000010041 electrostatic spinning Methods 0.000 claims description 11
- 238000000034 method Methods 0.000 claims description 9
- 239000011521 glass Substances 0.000 claims description 8
- 238000003760 magnetic stirring Methods 0.000 claims description 8
- 239000011259 mixed solution Substances 0.000 claims description 8
- 238000009987 spinning Methods 0.000 claims description 8
- 238000005303 weighing Methods 0.000 claims description 8
- 239000007788 liquid Substances 0.000 claims description 3
- 238000009452 anti-microbial packaging Methods 0.000 claims 2
- 239000012528 membrane Substances 0.000 abstract description 16
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 9
- 239000000835 fiber Substances 0.000 abstract description 7
- 239000003431 cross linking reagent Substances 0.000 abstract description 6
- 231100000252 nontoxic Toxicity 0.000 abstract description 5
- 230000003000 nontoxic effect Effects 0.000 abstract description 5
- 238000010521 absorption reaction Methods 0.000 abstract description 4
- 231100000331 toxic Toxicity 0.000 abstract description 4
- 230000002588 toxic effect Effects 0.000 abstract description 4
- 239000005003 food packaging material Substances 0.000 abstract description 2
- 239000003960 organic solvent Substances 0.000 abstract description 2
- 239000002861 polymer material Substances 0.000 abstract description 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 42
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 42
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 42
- 239000002121 nanofiber Substances 0.000 description 15
- 235000013305 food Nutrition 0.000 description 14
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 12
- 229910052782 aluminium Inorganic materials 0.000 description 12
- 239000011888 foil Substances 0.000 description 12
- 239000011248 coating agent Substances 0.000 description 6
- 238000000576 coating method Methods 0.000 description 6
- 230000000052 comparative effect Effects 0.000 description 5
- 238000004806 packaging method and process Methods 0.000 description 5
- 238000001878 scanning electron micrograph Methods 0.000 description 4
- 230000002349 favourable effect Effects 0.000 description 3
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 description 2
- XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 description 2
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 2
- 239000004372 Polyvinyl alcohol Substances 0.000 description 2
- 238000009456 active packaging Methods 0.000 description 2
- 238000009826 distribution Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000001523 electrospinning Methods 0.000 description 2
- 238000005538 encapsulation Methods 0.000 description 2
- RRAFCDWBNXTKKO-UHFFFAOYSA-N eugenol Chemical compound COC1=CC(CC=C)=CC=C1O RRAFCDWBNXTKKO-UHFFFAOYSA-N 0.000 description 2
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 239000005022 packaging material Substances 0.000 description 2
- 229920002451 polyvinyl alcohol Polymers 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 238000002791 soaking Methods 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- WYQZZUUUOXNSCS-YFKPBYRVSA-N (2r)-2-amino-3-(prop-2-enyldisulfanyl)propanoic acid Chemical compound OC(=O)[C@@H](N)CSSCC=C WYQZZUUUOXNSCS-YFKPBYRVSA-N 0.000 description 1
- GWIWSTVHQDDXNU-IUCAKERBSA-N (2s)-2-amino-5-[[(2r)-1-(carboxymethylamino)-1-oxo-3-(prop-2-enyldisulfanyl)propan-2-yl]amino]-5-oxopentanoic acid Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@H](C(=O)NCC(O)=O)CSSCC=C GWIWSTVHQDDXNU-IUCAKERBSA-N 0.000 description 1
- 240000002234 Allium sativum Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 108010077805 Bacterial Proteins Proteins 0.000 description 1
- NPBVQXIMTZKSBA-UHFFFAOYSA-N Chavibetol Natural products COC1=CC=C(CC=C)C=C1O NPBVQXIMTZKSBA-UHFFFAOYSA-N 0.000 description 1
- 244000223760 Cinnamomum zeylanicum Species 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 239000005770 Eugenol Substances 0.000 description 1
- AZKVWQKMDGGDSV-BCMRRPTOSA-N Genipin Chemical compound COC(=O)C1=CO[C@@H](O)[C@@H]2C(CO)=CC[C@H]12 AZKVWQKMDGGDSV-BCMRRPTOSA-N 0.000 description 1
- 108010024636 Glutathione Proteins 0.000 description 1
- 235000013878 L-cysteine Nutrition 0.000 description 1
- 239000004201 L-cysteine Substances 0.000 description 1
- 206010034203 Pectus Carinatum Diseases 0.000 description 1
- UVMRYBDEERADNV-UHFFFAOYSA-N Pseudoeugenol Natural products COC1=CC(C(C)=C)=CC=C1O UVMRYBDEERADNV-UHFFFAOYSA-N 0.000 description 1
- WYQZZUUUOXNSCS-UHFFFAOYSA-N S-allylmercapto-L-cysteine Natural products OC(=O)C(N)CSSCC=C WYQZZUUUOXNSCS-UHFFFAOYSA-N 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 235000017803 cinnamon Nutrition 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 230000001627 detrimental effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 235000019441 ethanol Nutrition 0.000 description 1
- 229960002217 eugenol Drugs 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 235000004611 garlic Nutrition 0.000 description 1
- AZKVWQKMDGGDSV-UHFFFAOYSA-N genipin Natural products COC(=O)C1=COC(O)C2C(CO)=CCC12 AZKVWQKMDGGDSV-UHFFFAOYSA-N 0.000 description 1
- 229960003180 glutathione Drugs 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 231100000086 high toxicity Toxicity 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 150000002898 organic sulfur compounds Chemical class 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000002250 progressing effect Effects 0.000 description 1
- 230000005476 size effect Effects 0.000 description 1
- 238000000807 solvent casting Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000003856 thermoforming Methods 0.000 description 1
- 150000003573 thiols Chemical class 0.000 description 1
- 238000002834 transmittance Methods 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
Images
Classifications
-
- D—TEXTILES; PAPER
- D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
- D04H—MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
- D04H1/00—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres
- D04H1/70—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres characterised by the method of forming fleeces or layers, e.g. reorientation of fibres
- D04H1/72—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres characterised by the method of forming fleeces or layers, e.g. reorientation of fibres the fibres being randomly arranged
- D04H1/728—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres characterised by the method of forming fleeces or layers, e.g. reorientation of fibres the fibres being randomly arranged by electro-spinning
-
- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
- D01F1/00—General methods for the manufacture of artificial filaments or the like
- D01F1/02—Addition of substances to the spinning solution or to the melt
- D01F1/10—Other agents for modifying properties
- D01F1/103—Agents inhibiting growth of microorganisms
-
- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
- D01F8/00—Conjugated, i.e. bi- or multicomponent, artificial filaments or the like; Manufacture thereof
- D01F8/04—Conjugated, i.e. bi- or multicomponent, artificial filaments or the like; Manufacture thereof from synthetic polymers
- D01F8/10—Conjugated, i.e. bi- or multicomponent, artificial filaments or the like; Manufacture thereof from synthetic polymers with at least one other macromolecular compound obtained by reactions only involving carbon-to-carbon unsaturated bonds as constituent
-
- D—TEXTILES; PAPER
- D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
- D04H—MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
- D04H1/00—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres
- D04H1/40—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties
- D04H1/42—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties characterised by the use of certain kinds of fibres insofar as this use has no preponderant influence on the consolidation of the fleece
- D04H1/4382—Stretched reticular film fibres; Composite fibres; Mixed fibres; Ultrafine fibres; Fibres for artificial leather
- D04H1/43825—Composite fibres
-
- D—TEXTILES; PAPER
- D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
- D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
- D10B2401/00—Physical properties
- D10B2401/02—Moisture-responsive characteristics
- D10B2401/021—Moisture-responsive characteristics hydrophobic
-
- D—TEXTILES; PAPER
- D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
- D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
- D10B2401/00—Physical properties
- D10B2401/02—Moisture-responsive characteristics
- D10B2401/022—Moisture-responsive characteristics hydrophylic
-
- D—TEXTILES; PAPER
- D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
- D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
- D10B2401/00—Physical properties
- D10B2401/13—Physical properties anti-allergenic or anti-bacterial
-
- D—TEXTILES; PAPER
- D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
- D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
- D10B2505/00—Industrial
- D10B2505/10—Packaging, e.g. bags
Landscapes
- Engineering & Computer Science (AREA)
- Textile Engineering (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Manufacturing & Machinery (AREA)
- Artificial Filaments (AREA)
- Manufacture Of Macromolecular Shaped Articles (AREA)
Abstract
The invention is suitable for the technical field of active food packaging materials, and provides an antibacterial packaging film loaded with garlicin and a preparation method thereof, wherein the antibacterial packaging film comprises the following components: allicin antimicrobial, polymers PVP and PVB; the sum of PVP and PVB accounts for 10% of the total solution mass; the allicin antibacterial agent accounts for 10% of the total polymer mass. The selected polymer materials are safe and nontoxic and have wide sources, the use of toxic and harmful organic solvents and cross-linking agents is avoided by selecting proper polymers, the fiber membrane with stable water absorption can be obtained by adjusting the proportion of PVP and PVB, the hydrophilicity and hydrophobicity of the fiber membrane can be adjusted by adjusting the proportion of PVP and PVB, and the fiber membrane is endowed with excellent antibacterial ability by adding allicin.
Description
Technical Field
The invention belongs to the technical field of active food packaging materials, and particularly relates to an allicin-loaded antibacterial packaging film and a preparation method thereof.
Background
With consumers focusing more and more on the quality, safety and freshness of food products, research on active food packaging has been rapidly progressing. The unique characteristic of the active package is that natural antibacterial factors (such as cinnamon essential oil, eugenol and the like) obtained by adding functional active factors (such as antibacterial agents) are usually nontoxic and have strong antibacterial activity, and a good choice is provided for the development of the antibacterial active package.
Allicin is an organic sulfur compound extracted from garlic bulbs. It has strong antibacterial effect, and can inhibit various gram-positive and gram-negative bacteria at very low concentration. Allicin can interact with thiols such as glutathione and L-cysteine in bacterial cells to form S-allylmercaptoglutathione and S-allylmercaptocysteine, respectively, potentially leading to detrimental structural changes in bacterial proteins. However, there is no report on the preparation of antibacterial food packaging films using allicin.
At present, solvent casting, extrusion, thermoforming and other methods have been applied to the encapsulation of active factors to develop active packaging. However, the commonly used methods involve high temperature/high pressure processes, which may destroy the activity of the heat-sensitive active factors. Electrospinning has been recognized as a convenient and versatile method of encapsulating sensitive bioactive factors. It is based on the preparation of nanofibers by electric forces, can be performed at room temperature, and allows efficient encapsulation and functional retention of active factors. In addition, the electrospun nanofiber membrane has a large specific surface area and extremely high porosity, is favorable for enlarging the contact area with the surface of food, and also is favorable for realizing high surface activity due to the nanometer size effect, thereby being favorable for packaging active food.
Polyvinyl alcohol (PVA), polyvinylpyrrolidone (PVP), polyethylene oxide (PEO), and the like have excellent spinnability and high safety, and are often used for food packaging by electrospinning alone or blending with food materials. However, they are highly hydrophilic and poorly water stable, and are not suitable for use in high moisture content food samples. Currently, cross-linking of electrospun nanofiber membranes is a common approach to solving this problem. However, most cross-linking agents are harmful. For example, Glutaraldehyde (GA) is a common cross-linking agent, has high toxicity, easily penetrates into food samples of packaging materials, and is harmful to food safety and consumer health. Some researchers also used genipin as a non-toxic cross-linking agent, but it is expensive and not suitable for food packaging. Therefore, there is a need to develop safe and economical methods to make these hydrophilic materials more suitable for food packaging. In the research, under the condition of not using any toxic and harmful toxic solvent (only using ethanol as a solvent) and a cross-linking agent, the hydrophilic PVP nano-fiber membrane is successfully converted into hydrophobicity by adding the nontoxic polymer PVB for blending electrostatic spinning. In addition, the PVP/PVB nanofiber membrane prepared has larger water absorption capacity due to the PVP.
The PVP/PVB-Allicin (PB64-A) nanofiber membrane is prepared by an electrostatic spinning method, and the prepared fiber membrane has broad-spectrum antibacterial activity, good hydrophobicity, stronger water absorption stability and good light blocking capability, has wide application prospect in the field of food active packaging materials, and is particularly suitable for meat foods.
Disclosure of Invention
The embodiment of the invention aims to provide an Allicin-loaded antibacterial packaging film and a preparation method thereof, and aims to prepare a PVP/PVB-Allicin (PB64-A) nanofiber film by an electrostatic spinning method.
The invention is realized in such a way that the allicin-loaded antibacterial packaging film comprises the following components:
allicin antimicrobial, polymers PVP and PVB; the sum of PVP and PVB accounts for 10% of the total solution mass; the allicin antibacterial agent accounts for 10% of the total polymer mass.
In a further technical scheme, the mass ratio of the PVP to the PVB is 3: 2.
A preparation method of an antibacterial packaging film loaded with garlicin is characterized by comprising the following steps:
step one, weighing a certain amount of PVP and PVB and adding into absolute ethyl alcohol;
step two, performing magnetic stirring for 12 hours at room temperature, and obtaining a PVP/PVB mixed solution after stirring;
step three, adding an allicin antibacterial agent into the solution obtained in the step two;
step four, continuously stirring until the liquid is in a semitransparent light yellow state, and stopping stirring;
and step five, putting the solution obtained in the step four into a glass tube for electrostatic spinning.
According to a further technical scheme, the spinning parameters in the step five are as follows: the voltage is 18kv and the pole distance is 18 cm.
According to the garlicin-loaded antibacterial packaging film and the preparation method thereof, the selected polymer materials are safe and non-toxic, and the source is wide, the use of toxic and harmful organic solvents and cross-linking agents is avoided by selecting proper polymers, the fiber film with stable water absorption can be obtained by adjusting the proportion of PVP and PVB, the hydrophilicity and hydrophobicity of the fiber film can be adjusted by adjusting the proportion of PVP and PVB, and the garlicin is added, so that the fiber film is endowed with excellent antibacterial capability.
Drawings
Fig. 1 is an SEM image and diameter distribution of PVP/PVB nanofibers provided by an embodiment of the present invention: (a, a) PVP, (B, B) PB91, (C, C) PB82, (D, D) PB73, (E, E) PB64, (F, F)) PB 55;
FIG. 2 is a schematic representation of the water contact angle of an electrospun PVP/PVB nanofiber membrane provided by an embodiment of the present invention;
FIG. 3 is SEM images of PVP/PVB nanofiber membrane prepared by soaking the PVP/PVB nanofiber membrane in water for 24 h, wherein the swelling ratio (A) and the mass loss (B) are respectively shown in PB73 (C), PB64 (D) and PB55 (E);
FIG. 4 is SEM image (A), diameter distribution (B) and water contact angle (C) of PB64-A nanofiber membrane provided by the embodiment of the invention, comparison graph of light transmittance (D), swelling ratio and mass loss (F) of PB64 and PB64-A nanofiber membrane, and SEM image of PB64-A nanofiber membrane after soaking in water for 24 h;
FIG. 5 is an evaluation of antibacterial activity of PB64 and PB64-A nanofiber membranes against E.coli (A, a) and Staphylococcus aureus (B, B) provided by an embodiment of the present invention;
FIG. 6 shows changes in TVB-N and pH during normal temperature storage of chicken breast provided by an embodiment of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
Specific implementations of the present invention are described in detail below with reference to specific embodiments.
Examples
Weighing PVP and PVB with the mass ratio of 3:2, adding the PVP and the PVB into absolute ethyl alcohol, carrying out magnetic stirring at room temperature for 12 hours, obtaining a PVP/PVB mixed solution after stirring is finished, adding an allicin antibacterial agent into the mixed solution, continuously stirring until the liquid is in a semitransparent faint yellow state, stopping stirring, wherein the allicin antibacterial agent in the obtained solution accounts for 10% of the total polymer mass, the sum of the masses of the PVP and the PVB accounts for 10% of the total solution mass, carrying out electrostatic spinning on the prepared solution, putting the solution into a glass tube with the diameter of 1mm, and carrying out spinning parameters as follows: voltage: 18kv, pole pitch: and (4) receiving the aluminum foil by a receiving plate, and coating the aluminum foil.
Comparative example 1
Weighing PVP and PVB in a mass ratio of 1:1, adding the PVP and the PVB into absolute ethyl alcohol, performing magnetic stirring at room temperature for 12 hours, obtaining a PVP/PVB mixed solution after stirring is finished, performing electrostatic spinning on the prepared solution, and filling the solution into a glass tube with the diameter of 1mm, wherein the spinning parameters are as follows: voltage: 18kv, pole pitch: and (4) receiving the aluminum foil by a receiving plate, and coating the aluminum foil.
Comparative example No. two
Weighing PVP and PVB with the mass ratio of 7:3, adding the PVP and the PVB into absolute ethyl alcohol, carrying out magnetic stirring for 12 hours at room temperature, obtaining a PVP/PVB mixed solution after stirring is finished, wherein the sum of the masses of the PVP and the PVB accounts for 10% of the total solution mass, carrying out electrostatic spinning on the prepared solution, putting the solution into a glass tube with the diameter of 1mm, and carrying out spinning parameters as follows: voltage: 18kv, pole pitch: and (4) receiving the aluminum foil by a receiving plate, and coating the aluminum foil.
Comparative example No. three
Weighing PVP and PVB with the mass ratio of 4:1, adding the PVP and the PVB into absolute ethyl alcohol, carrying out magnetic stirring for 12 hours at room temperature, obtaining a PVP/PVB mixed solution after stirring is finished, wherein the sum of the masses of the PVP and the PVB accounts for 10% of the total solution mass, carrying out electrostatic spinning on the prepared solution, putting the solution into a glass tube with the diameter of 1mm, and carrying out spinning parameters as follows: voltage: 18kv, pole pitch: and (4) receiving the aluminum foil by a receiving plate, and coating the aluminum foil.
Comparative example No. four
Weighing PVP and PVB with the mass ratio of 9:1, adding the PVP and the PVB into absolute ethyl alcohol, carrying out magnetic stirring for 12 hours at room temperature, obtaining a PVP/PVB mixed solution after stirring is finished, wherein the sum of the masses of the PVP and the PVB accounts for 10% of the total solution mass, carrying out electrostatic spinning on the prepared solution, putting the solution into a glass tube with the diameter of 1mm, and carrying out spinning parameters as follows: voltage: 18kv, pole pitch: and (4) receiving the aluminum foil by a receiving plate, and coating the aluminum foil.
Comparative example five
Weighing a certain amount of PVP, adding the PVP into absolute ethyl alcohol, carrying out magnetic stirring for 12 hours at room temperature, obtaining a PVP solution after stirring is finished, wherein the mass of the PVP accounts for 10% of the total solution mass, carrying out electrostatic spinning on the prepared solution, putting the solution into a glass tube with the diameter of 1mm, and carrying out spinning parameters as follows: voltage: 18kv, pole pitch: and (4) receiving the aluminum foil by a receiving plate, and coating the aluminum foil.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents and improvements made within the spirit and principle of the present invention are intended to be included within the scope of the present invention.
Claims (4)
1. An antibacterial packaging film loaded with garlicin is characterized by comprising the following components:
allicin antimicrobial, polymers PVP and PVB; the sum of PVP and PVB accounts for 10% of the total solution mass; the allicin antibacterial agent accounts for 10% of the total polymer mass.
2. The allicin-loaded antimicrobial packaging film of claim 1, wherein the mass ratio of PVP to PVB is 3: 2.
3. A method of preparing an allicin-loaded antimicrobial packaging film according to any one of claims 1 or 2, comprising the steps of:
step one, weighing a certain amount of PVP and PVB and adding into absolute ethyl alcohol;
step two, performing magnetic stirring for 12 hours at room temperature, and obtaining a PVP/PVB mixed solution after stirring;
step three, adding an allicin antibacterial agent into the solution obtained in the step two;
step four, continuously stirring until the liquid is in a semitransparent light yellow state, and stopping stirring;
and step five, putting the solution obtained in the step four into a glass tube for electrostatic spinning.
4. The method for preparing an allicin-loaded antibacterial packaging film according to claim 3, wherein the spinning parameters in the fifth step are: the voltage is 18kv and the pole distance is 18 cm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111499519.5A CN114150442A (en) | 2021-12-09 | 2021-12-09 | Garlicin-loaded antibacterial packaging film and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111499519.5A CN114150442A (en) | 2021-12-09 | 2021-12-09 | Garlicin-loaded antibacterial packaging film and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN114150442A true CN114150442A (en) | 2022-03-08 |
Family
ID=80453830
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202111499519.5A Pending CN114150442A (en) | 2021-12-09 | 2021-12-09 | Garlicin-loaded antibacterial packaging film and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114150442A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113134110A (en) * | 2020-01-16 | 2021-07-20 | 广州增城潮徽生物技术有限公司 | PVP/PVB slow-release nano-fiber medical dressing and preparation method and application thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012081744A1 (en) * | 2010-12-15 | 2012-06-21 | Ntpia Co., Ltd. | Polymer composite materials for building air conditioning or dehumidification and preparation method thereof |
| CN109881369A (en) * | 2019-02-27 | 2019-06-14 | 浙江工业大学 | A kind of preparation method for reinforcing antibacterial vapor-permeable type composite fibre static spinning membrane |
| CN110124094A (en) * | 2019-04-19 | 2019-08-16 | 青岛大学 | A kind of Chinese herbal medicine based micro-nano fibre antibacterial dressing be prepared in situ and application method |
| CN113134110A (en) * | 2020-01-16 | 2021-07-20 | 广州增城潮徽生物技术有限公司 | PVP/PVB slow-release nano-fiber medical dressing and preparation method and application thereof |
-
2021
- 2021-12-09 CN CN202111499519.5A patent/CN114150442A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012081744A1 (en) * | 2010-12-15 | 2012-06-21 | Ntpia Co., Ltd. | Polymer composite materials for building air conditioning or dehumidification and preparation method thereof |
| CN109881369A (en) * | 2019-02-27 | 2019-06-14 | 浙江工业大学 | A kind of preparation method for reinforcing antibacterial vapor-permeable type composite fibre static spinning membrane |
| CN110124094A (en) * | 2019-04-19 | 2019-08-16 | 青岛大学 | A kind of Chinese herbal medicine based micro-nano fibre antibacterial dressing be prepared in situ and application method |
| CN113134110A (en) * | 2020-01-16 | 2021-07-20 | 广州增城潮徽生物技术有限公司 | PVP/PVB slow-release nano-fiber medical dressing and preparation method and application thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113134110A (en) * | 2020-01-16 | 2021-07-20 | 广州增城潮徽生物技术有限公司 | PVP/PVB slow-release nano-fiber medical dressing and preparation method and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Wang et al. | Preparation, characterization, and 3D printing verification of chitosan/halloysite nanotubes/tea polyphenol nanocomposite films | |
| Poonguzhali et al. | Synthesis and characterization of chitosan-PVP-nanocellulose composites for in-vitro wound dressing application | |
| Min et al. | Novel antimicrobial packaging film based on porous poly (lactic acid) nanofiber and polymeric coating for humidity-controlled release of thyme essential oil | |
| Scaffaro et al. | Efficacy of poly (lactic acid)/carvacrol electrospun membranes against Staphylococcus aureus and Candida albicans in single and mixed cultures | |
| Tripathi et al. | Chitosan based antimicrobial films for food packaging applications | |
| Tarus et al. | Electrospun cellulose acetate and poly (vinyl chloride) nanofiber mats containing silver nanoparticles for antifungi packaging | |
| Yu et al. | Fabrication, characterization, and antibacterial properties of citric acid crosslinked PVA electrospun microfibre mats for active food packaging | |
| Wang et al. | Study on poly (vinyl alcohol)/carboxymethyl-chitosan blend film as local drug delivery system | |
| Elbarbary et al. | Radiation synthesis and characterization of polyvinyl alcohol/chitosan/silver nanocomposite membranes: antimicrobial and blood compatibility studies | |
| Nostro et al. | Control of biofilm formation by poly-ethylene-co-vinyl acetate films incorporating nisin | |
| EP3288600B1 (en) | Antibacterial nanofibres | |
| Vellora Thekkae Padil et al. | Fabrication, characterization, and antibacterial properties of electrospun membrane composed of gum karaya, polyvinyl alcohol, and silver nanoparticles | |
| Ibrahim et al. | Preparation and properties of carboxymethyl cellulose (CMC)/sodium alginate (SA) blends induced by gamma irradiation | |
| Gohargani et al. | Study on biodegradable chitosan‐whey protein‐based film containing bionanocomposite TiO2 and Zataria multiflora essential oil | |
| CN110792004A (en) | Antibacterial and oil-proof modification method of degradable food packaging paper | |
| Poonguzhali et al. | Synthesis and characterization of chitosan/poly (vinylpyrrolidone) biocomposite for biomedical application | |
| CN114150442A (en) | Garlicin-loaded antibacterial packaging film and preparation method thereof | |
| Ge et al. | Sustained broad-spectrum antimicrobial and haemostatic chitosan-based film with immerged tea tree oil droplets | |
| CN106757785A (en) | Silver-loaded chitosan/polyvinyl alcohol micron belt and preparation method and application thereof | |
| US20130052257A1 (en) | Antimicrobial hydrogel wound dressing | |
| Chen et al. | Chitosan–pullulan films enriched with Artemisia annua essential oil: Characterization and application in grape preservation | |
| Goudar et al. | Ionically crosslinked chitosan/tragacanth gum based polyelectrolyte complexes for antimicrobial biopackaging applications | |
| Yang et al. | Preparation of cationic polyelectrolyte grafted polyvinyl alcohol-formaldehyde macroporous hydrogels and their antibacterial properties | |
| An et al. | A sustainable and antimicrobial food packaging film for potential application in fresh produce packaging | |
| CN107875865B (en) | Antibacterial and pollution-resistant PVDF ultrafiltration membrane for water filtration |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20220308 |
|
| RJ01 | Rejection of invention patent application after publication |