CN114149904A - Noninvasive detection kit for hypertension gene in female gestation period - Google Patents
Noninvasive detection kit for hypertension gene in female gestation period Download PDFInfo
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- CN114149904A CN114149904A CN202111495140.7A CN202111495140A CN114149904A CN 114149904 A CN114149904 A CN 114149904A CN 202111495140 A CN202111495140 A CN 202111495140A CN 114149904 A CN114149904 A CN 114149904A
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/02—Laboratory benches or tables; Fittings therefor
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
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Abstract
The invention discloses a noninvasive detection kit for a hypertension gene of a female in gestation period, which comprises a base, a gasket, a detection box, a first ventilation opening, a second ventilation opening, a rotating shaft, a cover plate, a handle, a first motor, a rotating roller, fan blades, a temperature regulating box, a dust screen, an electric heating wire, a second motor, a fan, a lifting device, a connecting rod, a detection tube and a dust suction device, wherein the first ventilation opening is formed in the bottom of the detection box; the invention has reasonable and simple structure, low production cost, convenient installation and complete functions, and can circulate air to prevent bacteria from breeding by the aid of the first motor, the rotating roller and the fan blades; the height of the test board can be adjusted by the arranged lifting device, so that the test is more convenient; the invention can absorb the impurities such as dust in the detection box through the arranged dust suction device.
Description
Technical Field
The invention relates to the technical field of biological detection, in particular to a noninvasive detection kit for a hypertension gene in a female gestational period.
Background
Hypertensive disorders of pregnancy are specific diseases of pregnancy. Epidemiological investigations have shown that about 9.4% of pregnant women develop pregnancy-hypertension in varying degrees. The disease occurs after 20 weeks of gestation, and is clinically manifested as hypertension, proteinuria, edema, convulsion, coma and even death of mother and infant. To date, gestational hypertension remains a significant cause of maternal and peri-pediatric death; therefore, the noninvasive detection kit for the female gestational hypertension susceptibility gene is established simply and quickly, can detect the genotype of the female at the gene mononucleotide site related to the occurrence of gestational hypertension disease, screen out the female high risk group susceptible to gestational hypertension in time, and perform targeted pregnancy detection and guidance, and has very important significance for reducing the occurrence of pregnant and lying-in woman death, perinatal death and sick and residual children and ensuring the safety and health of mothers and infants, thereby providing the noninvasive detection kit for the female gestational hypertension gene.
Disclosure of Invention
The invention aims to provide a noninvasive detection kit for a female gestational hypertension gene to solve the problems, and solves the problems that a female high risk group susceptible to gestational hypertension cannot be screened out, and pregnancy detection and guidance cannot be performed specifically.
In order to solve the above problems, the present invention provides a technical solution: the noninvasive detection kit for the hypertension gene in the gestation period of the female has the innovation points that: the device comprises a base, a gasket, a detection box, a first ventilation opening, a second ventilation opening, a rotating shaft, a cover plate, a handle, a first motor, a rotating roller, fan blades, a temperature adjusting box, a dustproof net, an electric heating wire, a second motor, a fan, a lifting device, a connecting rod, a detection pipe and a dust suction device; a gasket is fixedly connected to the lower surface of the base; the upper end of the base is fixedly connected with a detection box; two sides of the lower end of the detection box are provided with first ventilation openings; two sides of the upper end of the detection box are provided with a second ventilation opening; two sides of the top end of the detection box are hinged with cover plates through rotating shafts; the top end of the cover plate is fixedly connected with a handle; the rear side of the upper end in the detection box cavity is fixedly connected with a first motor, an output shaft of the first motor is fixedly connected with a rotating roller, and the outer surface of the rotating roller is fixedly connected with a plurality of fans; the lower end of the detection box is fixedly connected with a lifting device; the connecting rod is fixedly connected to the lifting device; the connecting rod is connected with a plurality of detection tubes; and dust suction devices are connected to two sides of the detection box.
Preferably, the specific structure of the lifting device is as follows: the device comprises an installation block, a motor III, a screw block, a support rod, a detection table, a connecting plate and a through hole; the mounting blocks are fixedly connected to two sides of the bottom end inside the chamber of the detection box; the upper end of the mounting block is fixedly connected with a motor III, and an output shaft of the motor III is fixedly connected with a screw rod; the outer surface of the motor III is connected with a screw block through threads; the inner side of the screw block is fixedly connected with a supporting rod; the utility model discloses a bracing piece, including bracing piece, fixed connection has the connecting plate, the bracing piece inboard is connected with examines test table, fixedly connected with connecting plate on the bottom of bracing piece, be equipped with the several through-hole on the connecting plate.
Preferably, the dust suction device has a specific structure that: comprises a storage tank, a clapboard, an air pump, an air inlet pipe, an air inlet head, an air inlet pipe and a sewage outlet; the two sides of the outer end of the detection box are fixedly connected with storage boxes; a clapboard is fixedly connected inside the cavity of the storage box; the upper end of the partition board is fixedly connected with an air pump, the output end of the air pump is communicated with one end of an air inlet pipe, the other end of the air inlet pipe is communicated with an air inlet head, the input end of the air pump is communicated with one end of the air inlet pipe, and the other end of the air inlet pipe is positioned at the lower end of the inner part of the cavity of the storage box; the right side of the storage box is connected with a sewage draining outlet.
Preferably, the rotation angle of the rotating shaft is 0-90 degrees.
Preferably, the detection table is detachable.
Preferably, the motor three is a servo motor.
Preferably, the angle of the inlet head is adjustable.
Preferably, the air pump is a high-pressure air pump.
The invention has the beneficial effects that:
(1) the invention has the advantages of reasonable and simple structure, low production cost, convenient installation and complete functions, and can circulate air to prevent bacteria from breeding through the first motor, the rotating roller and the fan blades.
(2) The height of the test board can be adjusted by the lifting device, so that the test is more convenient.
(3) The invention can absorb the impurities such as dust in the detection box through the arranged dust suction device.
Drawings
FIG. 1 is a schematic structural diagram of the present invention.
Fig. 2 is a partially enlarged view of the present invention.
Fig. 3 is a schematic structural view of the dust suction device of the present invention.
1-a base; 2-a gasket; 3-a detection box; 4-a first ventilation opening; 5-air vent II; 6-a rotating shaft; 7-cover plate; 8-a grip; 9-motor one; 10-a rotating roll; 11-fan blades; 12-temperature regulating box; 13-dust screen; 14-electric heating wire; 15-motor two; 16-a fan; 17-a mounting block; 18-motor three; 19-a snail block; 20-a support bar; 21-detection table; 22-a connecting plate; 23-a through hole; 24-a connecting rod; 25-a detection tube; 26-a dust extraction device; 27-a storage tank; 28-a separator; 29-an air pump; 30-an air inlet pipe; 31-an air inlet head; 32-an air inlet pipe; 33-a sewage draining outlet.
Detailed Description
As shown in fig. 1 to 3, the following technical solutions are adopted in the present embodiment: the noninvasive gene detection kit for the hypertension of women in the gestation period comprises a base 1, a gasket 2, a detection box 3, a first vent 4, a second vent 5, a rotating shaft 6, a cover plate 7, a handle 8, a first motor 9, a rotating roller 10, fan blades 11, a temperature regulating box 12, a dust screen 13, an electric heating wire 14, a second motor 15, a fan 16, a lifting device, a connecting rod 24, a detection pipe 25 and a dust collection device 26; a gasket 2 is fixedly connected to the lower surface of the base 1; the upper end of the base 1 is fixedly connected with a detection box 3; two sides of the lower end of the detection box 3 are provided with a first ventilation opening 4; two sides of the upper end of the detection box 3 are provided with a second ventilation opening 5; thereby facilitating air circulation; two sides of the top end of the detection box 3 are hinged with cover plates 7 through rotating shafts 6; the top end of the cover plate 7 is fixedly connected with a handle 8; a first motor 9 is fixedly connected to the rear side of the upper end in the cavity of the detection box 3, a rotating roller 10 is fixedly connected to an output shaft of the first motor 9, and a plurality of fans 16 are fixedly connected to the outer surface of the rotating roller 10; thereby the air flow speed can be accelerated; the lower end of the detection box 3 is fixedly connected with a lifting device; the connecting rod 24 is fixedly connected to the lifting device; a plurality of detection tubes 25 are connected to the connecting rod 24; and dust suction devices 26 are connected to two sides of the detection box 3.
As shown in fig. 1 to 3, the specific structure of the lifting device is as follows: comprises a mounting block 17, a third motor 18, a screw block 19, a support rod 20, a detection table 21, a connecting plate 22 and a through hole 23; the mounting blocks 17 are fixedly connected to two sides of the bottom end in the chamber of the detection box 3; the upper end of the mounting block 17 is fixedly connected with a motor III 18, and an output shaft of the motor III 18 is fixedly connected with a screw rod; the outer surface of the motor III 18 is connected with a screw block 19 through threads; thereby facilitating height adjustment; the inner side of the screw block 19 is fixedly connected with a support rod 20; the inboard of bracing piece 20 is connected with examines test table 21, fixedly connected with connecting plate 22 on the bottom of bracing piece 20, be equipped with several through-hole 23 on the connecting plate 22.
As shown in fig. 1 to 3, the specific structure of the dust suction device 26 is as follows: comprises a storage tank 27, a clapboard 28, an air pump 29, an air inlet pipe 30, an air inlet head 31, an air inlet pipe 32 and a sewage outlet 33; the two sides of the outer end of the detection box 3 are fixedly connected with storage boxes 27; a partition plate 28 is fixedly connected inside the cavity of the storage tank 27; an air pump 29 is fixedly connected to the upper end of the partition 28, the output end of the air pump 29 is communicated with one end of an air inlet pipe 30, the other end of the air inlet pipe 30 is communicated with an air inlet head 31, the input end of the air pump 29 is communicated with one end of an air inlet pipe 32, and the other end of the air inlet pipe 32 is positioned at the lower end inside the cavity of the storage box 27; thereby effectively sucking out impurities; a drain outlet 33 is connected to the right side of the storage tank 27.
Wherein the rotation angle of the rotating shaft 6 is 0-90 degrees; the detection table 21 is detachable; the third motor 18 is a servo motor; the angle of the air inlet head 31 is adjustable; the air pump 29 is a high pressure air pump.
The using state of the invention is as follows: the invention has reasonable and simple structure, low production cost, convenient installation and complete functions, when in use, the position of the detection platform 21 is firstly adjusted by starting the motor III 18, the cover plate 7 is opened after adjustment, a sample to be detected is placed in the detection pipe 25, then the electric heating wire 14 is started, the motor II 15 is restarted to drive the fan 16 to upwardly transmit the temperature to the detection platform 21, when in detection, the motor I9 is started to drive the rotary roller 10 and the fan blades 11 to accelerate the air flow rate and improve the oxygen content, when in need of absorbing impurities in the detection box 3, the air pump 29 is started, and then the device is sucked into the storage box 27.
In the description of the present invention, it is to be understood that the terms "coaxial", "bottom", "one end", "top", "middle", "other end", "upper", "one side", "top", "inner", "front", "center", "both ends", and the like, indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of description and simplicity of description, and do not indicate or imply that the referenced device or element must have a particular orientation, be constructed and operated in a particular orientation, and thus, are not to be construed as limiting the present invention.
In the present invention, unless otherwise expressly specified or limited, the terms "mounted," "disposed," "connected," "secured," "screwed" and the like are to be construed broadly, e.g., as meaning fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; the terms may be directly connected or indirectly connected through an intermediate, and may be communication between two elements or interaction relationship between two elements, unless otherwise specifically limited, and the specific meaning of the terms in the present invention will be understood by those skilled in the art according to specific situations.
While there have been shown and described what are at present considered to be the fundamental principles of the invention and its essential features and advantages, it will be understood by those skilled in the art that the invention is not limited by the embodiments described above, which are merely illustrative of the principles of the invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the invention as defined by the appended claims and their equivalents.
The control mode of the invention is controlled by manually starting and closing the switch, the wiring diagram of the power element and the supply of the power source belong to the common knowledge in the field, and the invention is mainly used for protecting mechanical devices, so the control mode and the wiring arrangement are not explained in detail in the invention.
Claims (8)
1. The noninvasive gene detection kit for the hypertension of women in the gestation period is characterized in that: the device comprises a base (1), a gasket (2), a detection box (3), a first ventilation opening (4), a second ventilation opening (5), a rotating shaft (6), a cover plate (7), a handle (8), a first motor (9), a rotating roller (10), fan blades (11), a temperature adjusting box (12), a dust screen (13), an electric heating wire (14), a second motor (15), a fan (16), a lifting device, a connecting rod (24), a detection pipe (25) and a dust collection device (26);
a gasket (2) is fixedly connected to the lower surface of the base (1);
the upper end of the base (1) is fixedly connected with a detection box (3);
two sides of the lower end of the detection box (3) are provided with first ventilation openings (4);
two sides of the upper end of the detection box (3) are provided with a second ventilation opening (5);
two sides of the top end of the detection box (3) are hinged with cover plates (7) through rotating shafts (6);
the top end of the cover plate (7) is fixedly connected with a handle (8);
a first motor (9) is fixedly connected to the rear side of the upper end in the cavity of the detection box (3), a rotating roller (10) is fixedly connected to an output shaft of the first motor (9), and a plurality of fans (16) are fixedly connected to the outer surface of the rotating roller (10);
the lower end of the detection box (3) is fixedly connected with a lifting device;
the connecting rod (24) is fixedly connected to the lifting device;
a plurality of detection tubes (25) are connected to the connecting rod (24);
and two sides of the detection box (3) are connected with dust suction devices (26).
2. The noninvasive gene detection kit for hypertension in pregnancy of women according to claim 1, characterized in that: the specific structure of the lifting device is as follows: comprises a mounting block (17), a motor III (18), a screw block (19), a support rod (20), a detection table (21), a connecting plate (22) and a through hole (23);
the mounting blocks (17) are fixedly connected to two sides of the bottom end in the chamber of the detection box (3);
the upper end of the mounting block (17) is fixedly connected with a motor III (18), and an output shaft of the motor III (18) is fixedly connected with a screw rod;
the outer surface of the motor III (18) is connected with a screw block (19) through threads;
the inner side of the screw block (19) is fixedly connected with a support rod (20);
the utility model discloses a bracing piece, including bracing piece (20), bracing piece, fixed connection has connecting plate (22) on the bottom of bracing piece (20), be equipped with several through-hole (23) on connecting plate (22).
3. The noninvasive gene detection kit for hypertension in pregnancy of women according to claim 1, characterized in that: the dust suction device (26) has the following specific structure: comprises a storage tank (27), a clapboard (28), an air pump (29), an air inlet pipe (30), an air inlet head (31), an air inlet pipe (32) and a sewage outlet (33);
two sides of the outer end of the detection box (3) are fixedly connected with storage boxes (27);
a clapboard (28) is fixedly connected inside the cavity of the storage box (27);
an air pump (29) is fixedly connected to the upper end of the partition plate (28), the output end of the air pump (29) is communicated with one end of an air inlet pipe (30), the other end of the air inlet pipe (30) is communicated with an air inlet head (31), the input end of the air pump (29) is communicated with one end of an air inlet pipe (32), and the other end of the air inlet pipe (32) is located at the lower end inside a cavity of the storage box (27);
the right side of the storage tank (27) is connected with a sewage draining outlet (33).
4. The noninvasive gene detection kit for hypertension in pregnancy of women according to claim 1, characterized in that: the rotating angle of the rotating shaft (6) is 0-90 degrees.
5. The noninvasive gene detection kit for hypertension in pregnancy of women according to claim 2, characterized in that: the detection table (21) is detachable.
6. The noninvasive gene detection kit for hypertension in pregnancy of women according to claim 2, characterized in that: the third motor (18) is a servo motor.
7. The noninvasive gene detection kit for hypertension in pregnancy of women according to claim 3, characterized in that: the angle of the air inlet head (31) is adjustable.
8. The noninvasive gene detection kit for hypertension in pregnancy of women according to claim 3, characterized in that: the air pump (29) is a high-pressure air pump.
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CN202111495140.7A CN114149904A (en) | 2021-12-08 | 2021-12-08 | Noninvasive detection kit for hypertension gene in female gestation period |
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CN202111495140.7A CN114149904A (en) | 2021-12-08 | 2021-12-08 | Noninvasive detection kit for hypertension gene in female gestation period |
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Title |
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