CN114146326A - Measuring device for radiotherapy - Google Patents
Measuring device for radiotherapy Download PDFInfo
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- CN114146326A CN114146326A CN202111406672.9A CN202111406672A CN114146326A CN 114146326 A CN114146326 A CN 114146326A CN 202111406672 A CN202111406672 A CN 202111406672A CN 114146326 A CN114146326 A CN 114146326A
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- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/103—Treatment planning systems
- A61N5/1031—Treatment planning systems using a specific method of dose optimization
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
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- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N5/1071—Monitoring, verifying, controlling systems and methods for verifying the dose delivered by the treatment plan
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- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N5/1075—Monitoring, verifying, controlling systems and methods for testing, calibrating, or quality assurance of the radiation treatment apparatus
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- A—HUMAN NECESSITIES
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- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N5/1075—Monitoring, verifying, controlling systems and methods for testing, calibrating, or quality assurance of the radiation treatment apparatus
- A61N2005/1076—Monitoring, verifying, controlling systems and methods for testing, calibrating, or quality assurance of the radiation treatment apparatus using a dummy object placed in the radiation field, e.g. phantom
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Abstract
The embodiment of the application discloses measuring device for radiotherapy relates to the technical field of medical equipment, and solves the problem that measuring precision is low due to influence of environmental temperature in the related art. The measuring device for radiotherapy comprises a measuring module and a constant temperature module, wherein the measuring module comprises a measuring box filled with a liquid medium, and a detection assembly is arranged in the measuring box and used for measuring the amount of the ray water absorbent; the constant temperature module comprises a constant temperature box, the measuring module is arranged in the constant temperature box, a temperature adjusting component is further arranged in the constant temperature box, and the temperature adjusting component is used for adjusting the temperature in the constant temperature box. The measuring device for radiotherapy is used for measuring the water absorbed dose by a radiotherapy beam water yield thermal method.
Description
Technical Field
The embodiment of the application relates to but is not limited to the field of medical equipment, in particular to a measuring device for radiotherapy.
Background
The morbidity and mortality of cancer are the top in China. Cancer treatment is radiation therapy. Current phase radiotherapy techniques include photon radiotherapy and charged particle (proton and heavy ion) radiotherapy. In radiotherapy, the quality of protons and photons needs to be controlled, and in radiotherapy, the amount of a water absorbent of a proton beam/photon beam (hereinafter, referred to as a beam) is often used as a prescription dose for radiotherapy.
Radiotherapy radiation can bring water radiation temperature rise, thereby obtains water absorption absolute dose through measuring the change of temperature rise, but the temperature rise that arouses in the single radiotherapy process is less than 1 millikelvin, and resolution ratio is less, measures easily to be influenced by ambient temperature, has very big uncertainty, and measurement accuracy is difficult to guarantee.
Disclosure of Invention
The embodiment of the application provides a measuring device for radiotherapy, can accurate measurement beam's water absorbent volume.
The embodiment of the application provides a measuring device for radiotherapy, which comprises a measuring module and a constant temperature module, wherein the measuring module comprises a measuring box filled with a liquid medium, and a detection assembly is arranged in the measuring box and used for measuring the quantity of a ray water absorbent; the constant temperature module comprises a constant temperature box, the measuring module is arranged in the constant temperature box, a temperature adjusting component is further arranged in the constant temperature box, and the temperature adjusting component is used for adjusting the temperature in the constant temperature box.
The measuring device for radiotherapy provided by the embodiment of the application comprises a liquid medium, usually water, contained in a measuring box to form a water mold body capable of simulating human body components, a detection assembly in the measuring box is used for detecting the amount of water absorbent of a beam in the water mold body, a constant temperature module is arranged for obtaining more accurate measurement data, the measuring module is placed in a constant temperature box of the constant temperature module, so that heat exchange between the measuring module and the outside is isolated to a certain extent, interference of the outside temperature on a measurement result is avoided, the accuracy of the measurement data is further improved, meanwhile, a temperature adjusting assembly is also arranged in the constant temperature box and can adjust the temperature in the constant temperature box, the environmental temperature of the measuring module is further ensured to be constant, compared with the measuring module without the constant temperature module, the measuring device for radiotherapy provided by the application can obtain more accurate measurement data, thereby obtaining more accurate beam water absorbent dosage results.
In one possible implementation of the present application, the temperature adjustment assembly includes a heating member, a heat dissipation member, and a temperature sensing member.
The measuring device for radiotherapy that this application embodiment provided, in order to realize the regulation of the temperature in the thermostated container, the subassembly that adjusts the temperature has the heating member that can heat the intensification and the radiating piece of heat dissipation cooling, thereby open the temperature that heating member or radiating piece made in the thermostated container according to the demand and reach the demand temperature, thereby still be equipped with the temperature sensing piece in addition, the temperature of temperature sensing piece in to the thermostated container is gathered, provides the reference for the regulation of heating member and radiating piece.
In one possible implementation of the application, the heating element is arranged in a liquid medium in the measuring chamber.
The measuring device for radiotherapy that this application embodiment provided heats liquid medium for rapider, sets up the heating member in liquid medium, directly heats liquid medium to reach the purpose of quick change water die body temperature.
In one possible implementation manner of the present application, the heating element is a heating pipe, and a heating medium circulates in the heating pipe.
The measuring device for radiotherapy that this application embodiment provided, for gentler heating liquid medium, adopt the mode of water-bath heating, heating medium is along with water-bath system circulation flow in the heating pipe, gives the heating pipe with heat transfer, by heating liquid medium of heating pipe again, and whole heating process is steady easily to be controlled, compares in the direct heating, changes in the regulation, and can not produce interference factors such as bubble, increases this application measuring device for radiotherapy's precision.
In one possible implementation of the application, the heating tube is laid meandering along the measuring chamber inner wall.
The measuring device for radiotherapy that this application embodiment provided, in order to accelerate the heating efficiency of heating pipe, meanders the heating pipe and lays at measuring incasement wall, has increased the area of contact of heating pipe with liquid medium to can transmit more heat in the unit interval and give liquid medium, greatly improved heating efficiency.
In a possible implementation manner of the present application, the heat dissipation member includes a water-cooled tube, the water-cooled tube is disposed along an outer wall of the measurement box, and a plurality of water-cooled radiators are disposed on a path of the water-cooled tube.
The measuring device for radiotherapy that this application embodiment provided, in order to promote the cooling efficiency who measures case and inside liquid medium, adopt the water-cooling mode, the water-cooled tube contacts with measuring the case, can take away the heat of liquid medium through measuring the case fast, and the heat transfer that the water-cooled tube will be transmitted to the rethread water-cooled radiator is gone out to the realization is to the rapid cooling of the inside liquid medium of measuring case.
In a possible implementation manner of the application, the temperature sensing element is a plurality of temperature sensors, at least one temperature sensor is arranged inside the measuring box, and the rest temperature sensors are arranged at the top corner of the constant temperature box.
The embodiment of the application provides a measuring device for radiotherapy, in order to provide more accurate feedback data for the process of adjusting the temperature of the subassembly that adjusts the temperature, be provided with a plurality of temperature sensing pieces temperature sensor promptly, and at least one temperature sensor sets up in measuring incasement portion, a temperature for more accurate reaction liquid medium, remaining temperature sensor sets up in constant temperature box apex angle department and then can realize all-round measurement to the inside temperature of constant temperature box, a plurality of temperature sensor have more comprehensively reacted the inside temperature condition of constant temperature box, can provide more accurate feedback for the subassembly that adjusts the temperature, a plurality of temperature sensor simultaneous working simultaneously, also can increase the fault-tolerant rate.
In a possible implementation manner of the present application, the constant temperature module further includes a circulation component, the circulation component includes a plurality of fans, and the plurality of fans are sequentially arranged along a height direction of the measurement box.
The embodiment of the application provides a measuring device for radiotherapy, in order to make everywhere temperature keep the equilibrium in the thermostated container, the fan has been set up, fan work produces the air current, the air current is at the thermostated container inner loop flow, thereby bring the heat of the higher department of temperature to the lower position of temperature, everywhere temperature in the balanced thermostated container, measuring module ambient temperature's stability has further been promoted, because the space between thermostated container and the measuring box is comparatively long and narrow, whole thermostated container inner space is hardly filled with to the circulating air current that a fan provided, consequently, the direction of height along the measuring box sets up a plurality of fans simultaneously, the air current that a plurality of fans provided forms the powerful air current of encircleing the measuring box circulation, thereby further improve the work efficiency of fan.
In a possible implementation of the present application, the measuring chamber is placed in the incubator by means of a plurality of supports provided at the bottom thereof, with an air flow channel being left between the plurality of supports.
The measuring device for radiotherapy that this application embodiment provided, it is smooth and easy in order to guarantee that the air of measuring bottom of the case portion flows, separate measuring the case through support and thermostated container bottom plate, avoid measuring case and thermostated container direct contact to avoided a large amount of heats directly to conduct the thermostated container, leave the air current passageway between a plurality of supports, make things convenient for the circulating air current that the fan produced to pass through, thereby can effectively dispel the heat to measuring bottom of the case portion, avoid measuring bottom of the case portion heat to concentrate.
In a possible implementation manner of the present application, the detection assembly includes a displacement mechanism and a detector, the displacement mechanism is formed by sequentially stacking three linear displacement portions with mutually perpendicular extension directions, and the detector is connected to the last stacked linear displacement portion.
The measuring device for radiotherapy that this application embodiment provided, the detector is used for measuring the water absorbing agent volume of beam, is located the mechanism and then is used for driving the detector and removes in measuring the incasement, because displacement mechanism is formed by three extending direction mutually perpendicular's sharp displacement portion superposes in proper order, therefore displacement mechanism can take the detector to a plurality of positions of measuring the incasement.
In a possible implementation manner of the application, the middle part of one side of the measuring box is provided with an incidence window, the incidence window is detachably connected with a window body, and the thickness of the window body is smaller than that of the box wall of the measuring box.
The measuring device for radiotherapy that this application embodiment provided, for the ease of penetrating into of pencil, it has the entrance window to open in the side of measuring the case, and the thickness of entrance window is less than the wall thickness of measuring the case to reduce the wall thickness and see the interference of pencil, make measuring result more accurate.
In a possible implementation manner of the application, the device further comprises a controller, the measuring module and the constant temperature module are electrically connected with the controller, the controller comprises a temperature control unit and a measuring unit, the temperature control unit is used for controlling the constant temperature module, and the measuring unit is used for controlling the measuring module.
The embodiment of the application provides a measuring device for radiotherapy, in order to improve this application measuring device for radiotherapy's intellectuality, this application measuring device for radiotherapy still is equipped with the controller, the controller includes temperature control unit and measuring unit, correspond control constant temperature module and measuring module, temperature control unit can adjust the operation of the subassembly that adjusts the temperature, for example opening and stopping of fan, the heating member, opening and stopping of radiating piece, and can realize the heating member according to the temperature data that temperature sensing piece measured, the automatically regulated of radiating piece etc., form automatic feedback system, it is more intelligent, artificial intervention has been lacked, measuring error also can reduce, further improve measuring device for radiotherapy's measurement accuracy, measuring unit can control measuring module's displacement mechanism, thereby the programmed different positions of taking the caliber to the measuring box, be difficult for makeing mistakes, and positioning accuracy is high.
In a possible implementation manner of the application, the bottom of the incubator is provided with a lifting mechanism, the lifting mechanism is used for lifting the incubator relative to the ground, the lifting mechanism is electrically connected with the controller, and the controller is used for controlling the action of the lifting mechanism.
The measuring device for radiotherapy that this application embodiment provided can adapt to multiple scene for the measuring device for radiotherapy that makes this application, sets up elevating system bottom the thermostated container to can freely adjust the height of thermostated container and inside measurement module, the subassembly that adjusts the temperature, improved the measuring device for radiotherapy's of this application universality, controller control elevating system also more accurate easy realization.
In a possible implementation of this application, still include the liquid reserve tank and the pump body, the liquid reserve tank, measure the case, the pump body passes through the pipeline and connects gradually, and the pump body and controller electric connection, the controller is used for controlling the pump body and opens and stop.
The measuring device for radiotherapy that this application embodiment provided, for the convenience of supplementing or the discharge liquid medium of measuring the incasement, still be equipped with the liquid reserve tank and the pump body, the pump body can shift liquid medium between the liquid reserve tank and measuring the case, has removed the manual work from and has added or discharge liquid medium's operation to measuring the case, uses manpower sparingly more, and the controller control pump body opens and stops, the volume of control liquid medium that can be more accurate.
In a possible implementation manner of the application, the device further comprises a carrying plate, the carrying plate is connected with a handle, wheels are fixed at the bottom of the carrying plate, and the constant temperature box is placed on the carrying plate.
The measuring device for radiotherapy that this application embodiment provided, for the convenience of this application measuring device for radiotherapy's removal, place the thermostated container on carrying the thing board to carrying thing board bottom and setting up the wheel, the user can stimulate and carry the fixed handle on the thing board, thereby the convenient removes required position with this application measuring device for radiotherapy.
Drawings
Fig. 1 is a schematic structural diagram of a measurement module of a measurement apparatus for radiotherapy according to an embodiment of the present disclosure;
fig. 2 is a schematic structural diagram of a constant temperature module of a measuring device for radiotherapy according to an embodiment of the present application;
FIG. 3 is a cross-sectional view A-A of FIG. 2;
FIG. 4 is a cross-sectional view taken along line B-B of FIG. 2;
fig. 5 is an exploded view of a measuring box of a measuring device for radiotherapy according to an embodiment of the present application;
fig. 6 is a functional diagram of a controller of a measuring apparatus for radiotherapy according to an embodiment of the present disclosure;
fig. 7 is a front view of a measuring device for radiotherapy according to an embodiment of the present application;
FIG. 8 is a cross-sectional view of C-C of FIG. 7;
FIG. 9 is a cross-sectional view D-D of FIG. 7;
fig. 10 is an external view of a three-dimensional structure of a measuring device for radiotherapy according to an embodiment of the present application;
fig. 11 is an internal view of a three-dimensional structure of a measuring device for radiotherapy according to an embodiment of the present application;
fig. 12 is a schematic view of a bragg peak ionization chamber of a measuring apparatus for radiotherapy according to an embodiment of the present disclosure;
fig. 13 is a schematic diagram of a bragg peak moving device of a measuring device for radiotherapy according to an embodiment of the present application;
fig. 14 is a schematic view of a twenty-four needle point ionization chamber of a measuring apparatus for radiotherapy according to an embodiment of the present application;
fig. 15 is a schematic diagram of a twenty-four needle point moving device of a measuring device for radiotherapy according to an embodiment of the present application;
fig. 16 is a dose-depth curve of a measuring apparatus for radiotherapy according to an embodiment of the present application.
Reference numerals:
1-a measurement module; 11-a measuring box; a 111-linker; 112-an entrance window; 113-a window; 1131-window frame; 1132 — an incident portion; 12-a detection component; 121-a displacement mechanism; 1211 — a first electric cylinder; 1212-a slide rail; 1213-second electric cylinder; 1214-a slider; 1415-a third electric cylinder; 122-a detector; 1221-an ionization chamber; 1222-a support; 123-a liquid level meter; 13-a support; 2-constant temperature module; 21-a constant temperature box; 211-constant temperature base plate; 212-a fastener; 213-an incident structure; 22-a temperature regulating component; 221-heating element; 2211-straight line segment; 2212-curved section; 222-a heat sink; 2221-water-cooled tube; 2222-water-cooled radiator; 223-temperature sensing element; 23-a circulation assembly; 231-a fan; 3-a controller; 31-a temperature control unit; 32-a measurement unit; 321-absolute dose measurement; 322-relative dose measurement; 323-screening devices; 33-an auxiliary unit; 4-a lifting mechanism; 5-a liquid storage tank; 6-carrying plate; 61-a handle; 62-wheels; 7-an electric cabinet; 8-an electronic control box; 81-data line; 9-a cabinet body; 91-cabinet door.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present application clearer, specific technical solutions of the present application will be described in further detail below with reference to the accompanying drawings in the embodiments of the present application. The following examples are intended to illustrate the present application but are not intended to limit the scope of the present application.
In the embodiments of the present application, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the embodiments of the present application, "a plurality" means two or more unless otherwise specified.
In addition, in the embodiments of the present application, directional terms such as "upper", "lower", "left", and "right" are defined with respect to the schematically-placed orientation of components in the drawings, and it is to be understood that these directional terms are relative concepts, which are used for descriptive and clarifying purposes, and may be changed accordingly according to changes in the orientation in which the components are placed in the drawings.
In the embodiments of the present application, unless otherwise explicitly specified or limited, the term "connected" is to be understood broadly, for example, "connected" may be a fixed connection, a detachable connection, or an integral body; may be directly connected or indirectly connected through an intermediate.
In the embodiments of the present application, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other like elements in a process, method, article, or apparatus that comprises the element.
In the embodiments of the present application, words such as "exemplary" or "for example" are used to mean serving as an example, instance, or illustration. Any embodiment or design described herein as "exemplary" or "e.g.," is not necessarily to be construed as preferred or advantageous over other embodiments or designs. Rather, use of the word "exemplary" or "such as" is intended to present concepts related in a concrete fashion.
The embodiment of the application provides a measuring device for radiotherapy, which is used for measuring the water absorption amount of a proton beam/photon beam during radiotherapy, so that the characteristics of the beam are simulated and characterized when the beam passes through the body of a patient, and the radiation dose distribution in the body of the patient is determined, so that the beam can be prevented from irradiating nearby healthy or sensitive tissues during radiotherapy.
Referring to fig. 1 or fig. 2, the measuring device for radiotherapy provided in the embodiment of the present application includes a measuring module 1, where the measuring module 1 includes a measuring box 11 containing a liquid medium, and a detecting component 12 is disposed in the measuring box 11 and is used for measuring the amount of the radiation water absorbent. The liquid medium contained in the measuring chamber 11 is typically distilled water, forming a water phantom that simulates body composition, and a detection assembly 12 within the measuring chamber 11 is used to detect the amount of water absorbent in the beam in the water phantom.
Wherein, measurement box 11 is made by organic glass, the uncovered setting in upper portion of measurement box 11, so that pour into liquid medium and installation determine module 12, measurement box 11 is the cuboid, its outside dimension length 498 millimeters, wide 484 millimeters, high 386 millimeters, inside dimension length 480 millimeters, wide 448 millimeters, high 350 millimeters, measurement box 11 thickness is 18 millimeters, be connected with joint 111 in one side of measurement box 11, joint 111 will measure the inside and outside intercommunication of box 11, thereby be convenient for discharge the liquid medium in the measurement box 11.
In order to obtain more accurate measurement data, referring to fig. 2 to 4, in an embodiment of the present application, the measuring device for radiotherapy further includes a constant temperature module 2, the constant temperature module 2 includes a constant temperature box 21, and the measuring module 1 is disposed in the constant temperature box 21, so as to isolate the heat exchange between the measuring module 1 and the outside to a certain extent, avoid the interference of the outside temperature to the measurement result, and further improve the accuracy of the measurement data. In addition, a temperature adjusting unit 22 is provided in the oven 21, and the temperature adjusting unit 22 is used for adjusting the temperature in the oven 21. Thereby further guaranteed measuring module 1's ambient temperature invariant, compared in the measuring module 1 that does not set up constant temperature module 2, the measuring device for radiotherapy of this application can obtain more accurate measured data to obtain more accurate beam water absorbent quantity result.
Wherein, there are many realization ways for the structure of the thermostat 21, and any structure capable of separating the measuring module 1 from the external space to reduce the heat exchange with the outside is within the protection scope of the present application, referring to fig. 5, in an embodiment of the present application, the thermostat 21 is a regular hexahedron structure, the side length is 1000 mm, the thickness of each side is at least 50 mm, wherein, the bottom plate of the thermostat 21, i.e. the thermostatic bottom plate 211, has a larger thickness and can be detached from the thermostat 21, the specific thermostat 21 is connected with other side plates of the thermostat 21 through the threaded fasteners 212, the measuring box 11 and the temperature adjusting assembly 22 are both arranged on the thermostatic bottom plate 211, so that in the process of detaching the thermostat 21, only the side plates of the thermostat 21 except the thermostatic bottom plate 211 need to be detached without moving the thermostatic bottom plate 211, and interference can not be caused to the measuring module 1 inside, thereby ensuring that the measuring module 1 can operate independently from the thermostatic box 21, to adapt to measurement scenarios where the thermostat module 2 is not required.
It should be noted that six side surfaces of the incubator 21 are made of heat insulating materials, specifically, one material may be made, or a plurality of materials may be combined into a laminated board, thereby achieving the purpose of multi-layer heat insulation, and a vacuum layer may be added between layers to further reduce heat transfer and enhance heat insulation effect, and corresponding heat insulating materials include polyurethane, glass fiber cotton, and the like.
In order to achieve the adjustment of the temperature inside the oven 21, referring to fig. 3 or fig. 4, in an embodiment of the present application, the temperature adjustment assembly 22 includes a heating element 221, and when the temperature inside the oven 21 and the measuring chamber 11 is lower than the ambient temperature required for the measurement, the heating element 221 is turned on, so as to supplement the heat and keep the temperature inside the oven 21 constant.
The heating element 221 may heat the air in the thermostat 21, indirectly heat the liquid medium in the measurement box 11, or directly heat the liquid medium, so as to achieve the purpose of rapidly heating the temperature of the water mold body, and referring to fig. 3 or 4, in an embodiment of the present application, the heating element 221 is disposed in the liquid medium in the measurement box 11. The liquid medium is directly heated, so that the water mold body can quickly reach the temperature required by measurement.
For a milder heating liquid medium, refer to fig. 3 or fig. 4, in an embodiment of the present application, the heating member 221 is a heating pipe, a temperature adjustment range of the heating pipe is 0-30 degrees celsius, a heating medium flows in the heating pipe in a circulating manner, the specific heating medium is water with a temperature higher than that of the liquid medium in the measurement box 11, the heating medium circulates in the heating pipe in a conventional manner, the present application is not limited specifically, a water bath heating manner is adopted, the heating medium flows along with a water bath system in the heating member 221 in a circulating manner, heat is transferred to the heating member 221, and the liquid medium is heated by the heating member 221 again, the whole heating process is stable and easy to control, and is easier to be compared with direct heating, adjustment is performed, and no interference factors such as bubbles are generated, and the accuracy of the measuring device for radiotherapy of the present application is increased.
It should be noted that, the distribution of the heating element 221 in the measuring box 11 may have various forms, and in order to accelerate the heating efficiency of the heating pipe, referring to fig. 3 or fig. 4, in an embodiment of the present application, the heating element 221 is laid along the inner wall of the measuring box 11 in a meandering manner, specifically, the heating element 221 includes a plurality of straight line segments 2211 parallel to each other and a plurality of curved segments 2212 in a "U" shape, and the plurality of straight line segments 2211 and the plurality of curved segments 2212 are alternately connected, so as to form a meandering "S" shaped heating pipe, and the contact area between the heating pipe and the liquid medium is increased, so that more heat can be transferred to the liquid medium in a unit time, and the heating efficiency is greatly improved.
In addition, the temperature adjustment assembly 22 further includes a heat dissipation member 222, in order to improve the cooling efficiency of the measurement box 11 and the liquid medium inside the measurement box, referring to fig. 2 to 4, in an embodiment of the present application, the heat dissipation member 222 includes a water-cooled tube 2221, the water-cooled tube 2221 is disposed along an outer wall of the measurement box 11, specifically, the water-cooled tube 2221 is disposed on an outer side surface of the bottom of the measurement box 11, and a winding and laying manner same as that of a heating tube is adopted, a plurality of water-cooled heat sinks 2222 are disposed on a path of the water-cooled tube 2221, specifically, there are two water-cooled heat sinks 2222, and the two water-cooled heat sinks 2222 are disposed on the constant temperature base plate 211 and are centrally and symmetrically distributed on a diagonal line of the bottom surface of the measurement box 11. By adopting a water cooling mode, the water cooling tube 2221 is in contact with the measurement box 11, so that the heat of the liquid medium can be taken away quickly through the measurement box 11, and then the heat transferred to the water cooling tube 2221 is transferred out through the water cooling radiator 2222, thereby realizing the quick cooling of the liquid medium in the measurement box 11.
Accordingly, in order to provide a basis for the temperature adjusting process of the temperature adjusting assembly 22, referring to fig. 2 to 4, in an embodiment of the present application, the temperature adjusting assembly 22 further includes a temperature sensing element 223. The temperature sensing member 223 collects the temperature inside the oven 21, and provides a reference for the adjustment of the heating member 221 and the heat radiating member 222.
In order to provide more accurate feedback data for the temperature adjustment process of the temperature adjustment assembly 22, referring to fig. 2 to 4, in an embodiment of the present application, the plurality of temperature sensing elements 223 are provided, at least one temperature sensing element 223 is disposed inside the measurement box 11, the remaining temperature sensing elements 223 are disposed at the top corner of the incubator 21, four temperature sensing elements 223 are disposed outside the measurement box 11, and a connection line of any two of the four temperature sensing elements 223 is approximately a diagonal line of a corresponding surface of the measurement box 11. The temperature sensing piece 223 of measuring box 11 inside is used for the temperature of more accurate reaction liquid medium, and remaining temperature sensing piece 223 can realize the all-round measurement to the inside temperature of thermostated container 21, and a plurality of temperature sensing pieces 223 have more comprehensively reflected the inside temperature condition of thermostated container 21, can provide more accurate feedback for the subassembly 22 that adjusts the temperature, and a plurality of temperature sensing pieces 223 simultaneous workings simultaneously also can increase the fault-tolerant rate.
The temperature sensing element 223 is a temperature sensor, specifically a thermistor, and the temperature resolution of the thermistor located in the measuring box 11 is at least 0.001 kelvin.
In order to maintain the temperature at various positions in the oven 21 to be uniform, referring to fig. 2 to 4, in an embodiment of the present application, the thermostatic module 2 further includes a circulating assembly 23, the circulating assembly 23 includes a fan 231, the fan 231 is rectangular, an air inlet side and an air outlet side are both square with a side length of 60 mm, and a thickness of 30 mm. Fan 231 work produces the air current, and the air current circulates in thermostated container 21 to take the heat of the higher department of temperature to the lower position of temperature, the temperature of each department in balanced thermostated container 21, the difference in temperature of specific thermostated container 21 different points should be less than 1 degree centigrade under the effect of fan 231, has further promoted measuring module 1 ambient temperature's stability.
Since the space between the oven 21 and the measurement chamber 11 is narrow and long, it is difficult for the circulating air flow provided by one fan 231 to fill the entire space inside the oven 21, and thus the number of fans 231 is plural, the fans 231 are arranged in sequence along the height direction of the measurement chamber 11, and the air flows provided by the fans 231 form a strong air flow circulating around the measurement chamber 11, thereby further improving the working efficiency of the fans 231.
In order to ensure smooth air flow at the bottom of the measurement box 11, referring to fig. 1 to 3, in an embodiment of the present application, the measurement box 11 is placed in the incubator 21 through a plurality of supports 13 arranged at the bottom thereof, airflow channels are left between the plurality of supports 13, the number of the specific supports 13 is three, the three supports 13 are distributed on the outer side surface of the bottom of the measurement box 11 in a regular triangle, and the open space between the three supports 13 is the airflow channel. Support 13 avoids measuring case 11 and thermostated container 21 direct contact to avoided a large amount of heats to directly conduct thermostated container 21, left the air current passageway between a plurality of supports 13, made things convenient for the circulation air current that fan 231 produced to pass through, thereby can effectively dispel the heat to measuring case 11 bottom, avoid measuring case 11 bottom heat to concentrate.
In addition, the support 13 will also have an adjusting function, the height can be freely adjusted, and when the thermostatic bottom plate 211 of the thermostat 21 is in a non-horizontal plane, the height of the three supports 13 can be respectively adjusted, so that the measuring box 11 on the thermostatic bottom plate 211 is in a horizontal state to meet the measuring requirement.
Referring to fig. 1 to 4, the detecting assembly 12 includes a displacement mechanism 121 and a detector 122, the detector 122 is used for measuring the water absorbent amount of the beam, the displacement mechanism 121 is formed by sequentially overlapping three linear displacement portions with mutually perpendicular extending directions, the detector 122 is connected to the last overlapped linear displacement portion, the positioning mechanism is used for driving the detector 122 to move in the measuring box 11, and the displacement mechanism 121 is formed by sequentially overlapping three linear displacement portions with mutually perpendicular extending directions, so that the displacement mechanism 121 can bring the detector 122 to a plurality of positions in the measuring box 11.
It should be noted that the linear displacement portion includes a guide rail, a slider 1214, a linear actuator, etc., where the linear actuator may be a hydraulic cylinder, an air cylinder, etc., or an electric cylinder designed by integrating an electric motor and a lead screw, referring to fig. 1 to 4, in an embodiment of the present application, the displacement mechanism 121 includes a first electric cylinder 1211, the first electric cylinder 1211 is fixed on one side of the opening of the measurement box 11, a slide rail 1212 parallel to the action direction of the first electric cylinder 1211 is fixed on the corresponding side, the displacement mechanism 121 further includes a second electric cylinder 1213, one end of the second electric cylinder 1213 is connected to the lead screw portion of the first electric cylinder 1211 in a transmission manner, the first electric cylinder drives the second electric cylinder 1213 to move along the direction of the slide rail 1212, the other end of the second electric cylinder 1213 is connected to the slide rail 1212 in a sliding manner, the slide rail 1212 provides support, so as to stably support the second electric cylinder 1213, the lead screw portion of the second electric cylinder 1213 is connected to the slider 1214 in a transmission manner, the slide block 1214 is driven by the second electric cylinder 1213 and moves along the extending direction of the second electric cylinder 1213, the third electric cylinder 1415 is connected to the slide block 1214, the axis of the output shaft of the third electric cylinder 1415 is vertically arranged, and the output end of the third electric cylinder 1415 is connected to the detector 122.
Wherein, the detector 122 is a thermistor, the temperature resolution of the thermistor is at least 0.001 kelvin, in addition, the detector 122 can also be an ionization chamber 1221, the ionization chamber 1221 can be used for carrying out the conventional beam water absorbent quantity detection, and the conventional beam water absorbent quantity detection is complementary with the water quantity thermal method, thereby further improving the measurement precision. It should be noted that the ionization chamber 1221 is fixed at the output end of the third electric cylinder 1415 by a bracket 1222, the bracket 1222 and the ionization chamber 1221 are replaceable, and different types of beams can be measured by installing different types of ionization chambers 1221 and corresponding brackets 1222, and the reference is made to fig. 12 or 13 for the bragg peak ionization chamber 1221 and its moving device, and fig. 14 or 15 for the twenty-four needle point ionization chamber 1221 and its moving device.
The detection assembly 12 further comprises a level gauge 123, the level gauge 123 being arranged inside the measurement chamber 11 for measuring the liquid medium in the measurement chamber 11 and for providing data for measuring the water absorbent content of the beam.
In order to facilitate the injection of the beam, referring to fig. 5, in an embodiment of the present application, an entrance window 112 is opened in the middle of one side of the measurement box 11, the entrance window 112 is detachably connected with a window 113, and the thickness of the window 113 is smaller than that of the box wall of the measurement box 11. Thereby reducing the interference of the wall thickness to the beam and making the measurement result more accurate.
The shape of the entrance window 112 is various, for example, circular, square, etc., referring to fig. 5 or fig. 10, in an embodiment of the present application, the entrance window 112 is square, and is set in the middle of the side wall of the measurement box 11 far from the heater, the window 113 includes a square window frame 1131, the window frame 1131 is connected to the side wall of the measurement box 11 through bolts located at four corners, a circular entrance portion 1132 is embedded in the middle of the window frame 1131, the thickness of the entrance portion 1132 is 5 mm, and it should be noted that the thermostat 21 is also provided with a corresponding entrance structure 213 corresponding to the position of the entrance window 112.
In order to improve the intelligence of the measuring device for radiotherapy in the present application, referring to fig. 6, in an embodiment of the present application, the measuring device further includes a controller 3, the measuring module 1 and the constant temperature module 2 are both electrically connected to the controller 3, the controller 3 includes a temperature control unit 31 and a measuring unit 32, the temperature control unit 31 is configured to control the constant temperature module 2, and the operation of the temperature adjustment component 22 can be adjusted, for example, the start and stop of the fan 231, the start and stop of the heating element 221 and the heat dissipation element 222, and the automatic adjustment of the heating element 221, the heat dissipation element 222 and the like can be realized according to the temperature data measured by the temperature sensing element 223, so as to form an automatic feedback system, which is more intelligent, reduces manual intervention, reduces measurement errors, and further improves the measurement accuracy of the measuring device for radiotherapy. The measuring unit 32 is used for controlling the measuring module 1, and the measuring unit 32 can control the displacement mechanism 121 of the measuring module 1, so that the measurer can be taken to different positions in the measuring box 11 in a programmed manner, errors are not prone to occur, and the positioning precision is high.
The specific measurement unit 32 has three functions, one of which is an absolute dose measurement 321 function that automatically gives the amount of water absorbent at the original reading by a water absorbent amount calculation method, controls the coordinates of the detector 122 in the water tank without measurement, and corrects the original charge reading, an air density correction factor, an air humidity correction factor, a polarity correction factor, a beam quality (ion beam type, energy, irradiation condition) correction factor, an ion recombination correction factor, and the like. The second function is a relative dose measurement 322 function, which controls the measurement of the detector 122 in the measurement box 11, and the graphical representation, calculation (curve smoothing, statistical analysis, etc.), storage and calling functions of the measurement data, and analyzes the data such as the name, number, total class of particles, energy, incident angle, and field range of the radiation device. And thirdly, the device screening 323 function can be used for inputting and editing the information of the irradiation device, the static meter and the detector, and selecting the model of the corresponding irradiation device, the model of the static meter and the model of the detector for subsequent data processing and analysis.
In order to enable the measuring device for radiotherapy to be capable of adapting to various scenes, referring to fig. 7 or 8, in an embodiment of the present application, a lifting mechanism 4 is disposed at the bottom of a thermostat 21, the specific lifting mechanism 4 is an electric telescopic rod, the stroke is 0-500 mm, the lifting error is less than 1 mm, the lifting mechanism 4 is used for lifting the thermostat 21 relative to the ground, the lifting mechanism 4 is electrically connected with a controller 3, and the controller 3 has an auxiliary unit 33 for controlling the movement of the lifting mechanism 4. Set up elevating system 4 in thermostated container 21 bottom to can freely adjust thermostated container 21 and inside measuring module 1, the height of subassembly 22 adjusts the temperature, improve the measuring device's for the radiotherapy universality of this application, controller 3 control elevating system 4 is also more accurate easily to be realized.
For the convenience of supplementing or discharging the liquid medium in the measurement box 11, refer to fig. 11, in an embodiment of this application, still include the liquid reserve tank 5 and the pump body, the liquid reserve tank 5, the measurement box 11, the pump body pass through the pipeline and connect gradually, and the pump body can adopt the immersible pump also can be external pump, and the pump body all adopts conventional connected mode with the pipeline, and the two is not shown in the figure, and the pump body and 3 electric connections of controller, the controller 3 have auxiliary unit 33 and be used for controlling the pump body to open and stop. The pump body can shift liquid medium between liquid reserve tank 5 and measuring box 11, has removed the manual work from and has added or discharge liquid medium's operation to measuring box 11, uses manpower sparingly more, and 3 control pump bodies of controller open and stop, the volume of control liquid medium that can be more accurate.
For the convenience of this application measuring device's removal for radiotherapy, refer to fig. 9-11, in an embodiment of this application, still including carrying thing board 6, the one end of carrying thing board 6 is connected with handle 61, and carries thing board 6 bottom and be fixed with wheel 62, and specific wheel 62 is the universal wheel that the area brake can be leveled, and four total wheels 62 divide and locate the four corners of carrying thing board 6 bottom, and thermostated container 21 places on carrying thing board 6. The user can pull the handle 61 fixed on the object carrying plate 6, thereby conveniently moving the measuring device for radiotherapy of the application to a required position.
Wherein, referring to fig. 7-11, the thermostat 21 is connected to the object carrying plate 6 through the lifting mechanism 4, i.e. the electric telescopic rod, the lower end of the electric telescopic rod is fixed to the object carrying plate 6, the upper end, i.e. the output end, is fixed to the constant temperature bottom plate 211, the liquid storage tank 5 is placed in the space between the constant temperature bottom plate 211 and the object carrying plate 6, the electric cabinet 7 is arranged on the side of the lifting mechanism 4 away from the liquid storage tank 5, the electric cabinet 7 is fixed to the upper side of the object carrying plate 6, the circuit system and the controller 3 required by the device in operation are arranged in the electric cabinet 7, the electric control box 8 is fixed on the sliding block 1214, the electric control box 8 is electrically connected with the electric cabinet 7, the electric control box 8 is used for driving the displacement mechanism 121 to move, the electric control box 8 is led out a data line 81 capable of being connected to the computer terminal, in addition, the cabinet body 9 is arranged between the constant temperature bottom plate 211 and the object carrying plate 6, the cabinet body 9 is fixed to the object carrying plate 6, the liquid storage tank 5, the electric cabinet 7 and the electric cabinet 7, Elevating system 4 all is located cabinet body 9, and one side of cabinet body 9 is equipped with cabinet door 91, opens cabinet door 91 and is convenient for maintain the equipment in the cabinet body 9.
Referring to fig. 16, by testing the measuring device for radiotherapy of the present application, a dose-depth curve of the measuring device is obtained to meet actual clinical requirements, and a measured bragg peak meets physical characteristics of a proton beam, wherein the specific measurement conditions include that a proton cyclotron is adopted, the energy of the proton beam is 95 megaelectron volts, the depth of a measurement box 11 is taken as a longitudinal axis, the measurement direction is from top to bottom, the source-skin distance is 1300 mm, the field type is selected from a square field, the angle of a rack is 90 degrees, the angle of a wedge plate is 0 degree, the temperature is controlled to be 20 degrees, the calibration factor is 1, and the maximum dose rate is 200 gray per second (Gy/s). The above-mentioned serial numbers of the embodiments of the present application are merely for description and do not represent the merits of the embodiments. The above description is only a preferred embodiment of the present application, and not intended to limit the scope of the present application, and all modifications of equivalent structures and equivalent processes, which are made by the contents of the specification and the drawings of the present application, or which are directly or indirectly applied to other related technical fields, are included in the scope of the present application.
Claims (15)
1. A measuring device for radiotherapy, comprising:
the measuring module comprises a measuring box filled with liquid medium, and a detecting component is arranged in the measuring box and used for measuring the quantity of the ray water absorbent;
the constant temperature module comprises a constant temperature box, the measuring module is arranged in the constant temperature box, a temperature adjusting component is further arranged in the constant temperature box, and the temperature adjusting component is used for adjusting the temperature in the constant temperature box.
2. The measuring device for radiotherapy according to claim 1, wherein the temperature adjusting unit comprises a heating member, a heat radiating member and a temperature sensing member.
3. A measuring device for radiation therapy according to claim 2, characterized in that said heating element is arranged in a liquid medium in said measuring chamber.
4. The measuring device for radiotherapy according to claim 3, wherein the heating member is a heating pipe in which a heating medium circulates.
5. The measuring device for radiotherapy according to claim 4, wherein the heating tube is laid in a meandering manner along the inner wall of the measuring chamber.
6. The measuring device for radiotherapy according to claim 2, wherein the heat dissipating member comprises a water-cooled tube, the water-cooled tube is disposed along an outer wall of the measuring chamber, and a plurality of water-cooled heat sinks are disposed on a path of the water-cooled tube.
7. The measuring device for radiotherapy according to claim 2, wherein the temperature sensing member is a plurality of temperature sensors, at least one of the temperature sensors is disposed inside the measuring chamber, and the remaining temperature sensors are disposed at corners of the top of the thermostatic chamber.
8. The measuring apparatus for radiation therapy according to claim 1, wherein said constant temperature module further comprises a circulation assembly, said circulation assembly comprising a plurality of fans, said plurality of fans being arranged in sequence in a height direction of said measuring chamber.
9. The measuring apparatus for radiation therapy according to claim 1, wherein said measuring chamber is placed in said incubator by a plurality of supports provided on a bottom thereof, and an air flow path is left between said plurality of supports.
10. The measuring apparatus for radiotherapy according to claim 1, wherein the detecting unit comprises a displacement mechanism and a detector, the displacement mechanism is formed by sequentially stacking three linear displacement portions having mutually perpendicular extending directions, and the detector is connected to the last stacked linear displacement portion.
11. The measuring device for radiotherapy according to claim 1, wherein an entrance window is formed in the middle of one side of the measuring chamber, a window is detachably connected to the entrance window, and the thickness of the window is smaller than that of the wall of the measuring chamber.
12. The measuring device for radiotherapy according to claim 1, further comprising a controller, wherein the measuring module and the constant temperature module are electrically connected to the controller, the controller comprises a temperature control unit and a measuring unit, the temperature control unit is used for controlling the constant temperature module, and the measuring unit is used for controlling the measuring module.
13. The measuring device for radiotherapy according to claim 12, wherein a lifting mechanism is disposed at a bottom of the incubator, the lifting mechanism is configured to lift the incubator relative to the ground, and the lifting mechanism is electrically coupled to the controller, and the controller is configured to control the lifting mechanism to operate.
14. The measuring device for radiotherapy according to claim 12, further comprising a liquid storage tank and a pump body, wherein the liquid storage tank, the measuring tank and the pump body are sequentially connected through a pipeline, the pump body is electrically connected with the controller, and the controller is configured to control the pump body to start and stop.
15. The measuring device for radiotherapy according to any one of claims 1 to 14, further comprising a carrying plate, wherein the carrying plate is connected with a handle and wheels are fixed at the bottom of the carrying plate, and the incubator is placed on the carrying plate.
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Application publication date: 20220308 |