CN114145729A - Intraabdominal pressure monitoring system based on epidermis electronics - Google Patents

Intraabdominal pressure monitoring system based on epidermis electronics Download PDF

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Publication number
CN114145729A
CN114145729A CN202111298852.XA CN202111298852A CN114145729A CN 114145729 A CN114145729 A CN 114145729A CN 202111298852 A CN202111298852 A CN 202111298852A CN 114145729 A CN114145729 A CN 114145729A
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flexible
processing unit
signal processing
intra
signal
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陈致尧
胡诚
夏庆
邓力珲
黎贵湘
王定玺
朱姝
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West China Hospital of Sichuan University
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West China Hospital of Sichuan University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/03Detecting, measuring or recording fluid pressure within the body other than blood pressure, e.g. cerebral pressure; Measuring pressure in body tissues or organs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6843Monitoring or controlling sensor contact pressure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/74Details of notification to user or communication with user or patient ; user input means
    • A61B5/742Details of notification to user or communication with user or patient ; user input means using visual displays
    • A61B5/7445Display arrangements, e.g. multiple display units

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)

Abstract

The invention belongs to the technical field of medical equipment, and discloses an intra-abdominal pressure monitoring system based on epidermal electronics, which comprises a sensing unit, a signal processing unit, an LED display screen and a His system, wherein the sensing unit is connected with the signal processing unit through wireless Bluetooth, the signal processing unit is electrically connected with the LED display screen and the His system, the sensing unit is epidermal electronics, the epidermal electronics comprise a flexible substrate layer, a dielectric layer, a flexible piezoelectric sensor, an active layer and a flexible battery, the flexible substrate layer is positioned at the bottom layer, the dielectric layer is positioned on the upper surface of the flexible substrate layer and is connected with an electrode, a signal processing unit comprises an amplifier, a filter and a converter, the signal processing unit converts a digital signal into an analog signal and then displays the analog signal on the LED display screen and uploads the analog signal to the His system, and the His system stores intra-abdominal pressure physiological parameter data for a long time; the method solves the problems of complicated operation links, poor experience of patients and low accuracy of measurement results in the prior art for measuring the intra-abdominal pressure, and is suitable for monitoring the intra-abdominal pressure.

Description

Intraabdominal pressure monitoring system based on epidermis electronics
Technical Field
The invention relates to the technical field of medical equipment, in particular to an intra-abdominal pressure monitoring system based on epidermal electronics.
Background
The epidermal electronics is an electronic device which is based on an ultrathin flexible substrate, has thickness, quality, density and flexibility well matched with human skin, and has the advantages of high sensitivity and quick response time. It is also called electronic tattoo because it can be absorbed on the skin without feeling, and is like tattoo, and has been used for vital signal monitoring (heart rate, respiration, myoelectricity, gastrointestinal motility), wearable rehabilitation therapy and the like in clinic. Intra-abdominal hypertension is a critical symptom that can cause organ tissue hypoperfusion, and persistent intra-abdominal hypertension with new organ failure can progress to inter-abdominal compartment syndrome, seriously and even endanger the life of the patient. Intra-abdominal hypertension is very common in patients with severe acute pancreatitis, abdominal trauma, sepsis, abdominal surgery. Therefore, intra-abdominal pressure has become the sixth vital sign following body temperature, blood pressure, heart rate, respiration, and oxygen saturation.
Currently, there are direct monitoring methods and indirect monitoring methods for monitoring intra-abdominal pressure. The direct pressure measurement method is that a catheter or a thick needle head is placed in an abdominal cavity, and abdominal pressure is directly measured by using a water pressure meter, a pressure sensor, a laparoscope pneumoperitoneum machine, an implanted inflatable air bag and the like, although the direct pressure measurement method can accurately measure the intra-abdominal pressure, the direct pressure measurement method cannot be conveniently and effectively popularized due to the risks of trauma and easy infection; the indirect pressure measurement method is to measure the abdominal pressure indirectly by measuring the pressure of bladder, rectum, stomach and inferior vena cava, wherein the bladder pressure monitoring is the 'gold standard' for the current determination of the intra-abdominal pressure due to the simple method, small wound and good correlation. The main method for measuring the bladder pressure at present is to arrange a urinary catheter, empty the bladder, inject a certain amount of normal saline into the bladder through the urinary catheter, and then connect a pressure sensor to measure the pressure of the liquid discharged from the bladder. Although the method is simple and easy to operate and has good repeatability, the following problems exist in clinical operation:
1. the operation link is complicated, when measuring the pressure, medical staff need to inject physiological saline into the bladder of a patient firstly, measure and read the height of the infusion tube by using a meter ruler after liquid is discharged, convert a centimeter water column into a millimeter mercury column, and finally write a result to a His system (hospital management system), the whole pressure measuring process is complicated and time-consuming, and under the condition that the medical staff is insufficient at night or in peak time and the like, the bladder pressure can not be converted in time after measurement is finished, even the data is lost;
2. the experience of a patient is poor, the bladder pressure monitoring is usually carried out once every 4-6 hours, the repeated operation can bring discomfort to the patient on the body and the mind, and the continuous intra-abdominal pressure change of the patient cannot be completely reflected even if the intermittent monitoring is carried out at a time point every 4-6 hours;
3. the accuracy of the result is low, in the actual bladder pressure measurement, the body position of the patient is often required to be matched, medical staff select the correct measurement position and measure at the end of expiration of the patient, and various human factors easily influence the accuracy of the final result in the measurement process.
Disclosure of Invention
The invention aims to provide an intra-abdominal pressure monitoring system based on epidermal electronics, which is designed by setting a sensor in an epidermal electronic form and combining the characteristics of the actual medical environment, solves the problems in the traditional intra-abdominal pressure monitoring and realizes accurate, convenient, stable and real-time intra-abdominal pressure monitoring.
In order to achieve the above purpose, the invention provides the following technical scheme:
the utility model provides an intra-abdominal pressure monitoring system based on epidermis electron, includes sensing unit, signal processing unit, LED display screen and His system, the sensing unit with the signal processing unit passes through wireless bluetooth and connects, the signal processing unit with the LED display screen with His system electric connection, the sensing unit is the epidermis electron, the epidermis electron is used for gathering monitoring intra-abdominal pressure physiological parameter data and converts it into the signal of telecommunication and save, the signal processing unit reads and receives intra-abdominal pressure physiological parameter data in real time, the signal processing unit is still handled intra-abdominal pressure physiological parameter data, shows after converting digital signal into analog signal on the LED display screen and go up to the His system, the His system carries out long-term storage to intra-abdominal pressure physiological parameter data.
Further, the signal processing unit comprises an amplifier, a filter and a converter, wherein the amplifier is used for shaping and amplifying the electrical signal, the filter is used for digitally filtering the amplified signal and removing the noise signal, and the converter is used for converting the amplified and filtered signal into a digital signal.
Further, the epidermis electron includes flexible stratum basale, dielectric layer, flexible piezoelectric sensor, active layer and flexible battery from up in proper order down, flexible stratum basale is located the bottom and pastes in skin, the dielectric layer is located the upper surface on flexible stratum basale and is connected with the electrode, flexible piezoelectric sensor gathers abdominal cavity's mechanical pressure change to change abdominal cavity's mechanical pressure into electrical signal, through the electrode with electrical signal transmission for signal processing unit, flexible battery is used for flexible piezoelectric sensor's power supply.
Further, the flexible substrate layer is one of polydimethylsiloxane, polyethylene terephthalate, polyimide, polyethylene or polyurethane.
Further, the dielectric layer is an electric insulating material, and the dielectric layer is one of polydimethylsiloxane, inorganic nano-ions, ferroelectric nano-ion barium titanate, metal nano-particle conductive fillers, conductive polymers or carbon nano-tubes.
Further, the flexible piezoelectric sensor is one of inorganic piezoelectric materials of lead zirconate titanate or zinc oxide.
Further, the active layer is a carbon nanotube-based active material, a graphene-based active material, and one of silicon, zinc oxide, gallium arsenide, or cadmium selenide, which is elastically compliant with the structural active material.
Further, the flexible battery is a flexible thin film battery including one of a flexible lithium electronic battery, a Li-S flexible battery, a stretchable organic solar cell, or a filmed fuel cell.
Further, the electrode is one of conductive non-woven fabric, copper foil or graphene.
The principle and the beneficial effects of the technical scheme are as follows:
1. the sensing unit is epidermis electron, and the epidermis electron is flexible monitoring electrode, forms monitoring circuit after connecting sensing unit and signal processing unit through wireless bluetooth, can realize whole intra-abdominal pressure monitoring system's design, has following advantage:
comfort: compared with the traditional bladder pressure monitoring method, the flexible basal layer of the epidermal electronics is utilized to naturally adsorb the skin, a monitored object cannot feel the existence of the sensor, no discomfort is caused in the installation and removal processes, and the skin cannot be damaged;
real-time performance: a flexible piezoelectric sensor of the epidermis electronics collects and uploads intra-abdominal pressure parameters in real time;
the accuracy is as follows: the flexible sensor of the epidermis electron is directly and closely attached to the surface of the human body, even under the condition that the skin is deformed, the continuous measurement of the signal can be realized, and the accuracy of the measurement result is ensured;
portability: the epidermis electron is frivolous small and exquisite, and flexible sensor and signal processing unit separation are handed the data of collecting and are handled by signal processing unit, and signal processing unit connects his system, and the people of being convenient for are operated rapidly.
2. The invention is provided with a signal processing unit and an LED display screen, and can display data such as intra-abdominal pressure value, urine volume per hour, accumulated urine volume and the like of a monitored object in real time. Meanwhile, the signal processing unit is interconnected with the information of the His system in the hospital, and medical personnel can retrospectively check the change trend of the current intra-abdominal pressure of the monitored object in the His system so as to conveniently and timely adjust the treatment scheme.
3. The sensing unit arranged in the invention can convert the detected pressure signal into an electric signal, and the output result is millimeter mercury, thereby simplifying the complicated calculation process.
Drawings
FIG. 1 is a schematic diagram of an intra-abdominal pressure monitoring system based on epidermal electronics in accordance with the present invention;
FIG. 2 is a schematic diagram of a structure of a skin electron of an intra-abdominal pressure monitoring system based on skin electrons according to the present invention;
the names of corresponding labels in the drawings are:
the flexible piezoelectric sensor comprises a flexible substrate layer 1, a dielectric layer 2, a flexible piezoelectric sensor 3, an active layer 4 and a flexible battery 5.
Detailed Description
The invention is described in further detail below with reference to the following figures and embodiments:
as shown in fig. 1 and fig. 2, an intra-abdominal pressure monitoring system based on epidermal electronics comprises a sensing unit, a signal processing unit, an LED display screen and a His system, wherein the sensing unit is connected with the signal processing unit through a wireless bluetooth, the signal processing unit is electrically connected with the LED display screen and the His system, the sensing unit is epidermal electronics, the epidermal electronics sequentially comprises a flexible substrate layer 1, a dielectric layer 2, a flexible piezoelectric sensor 3, an active layer 4 and a flexible battery 5 from bottom to top, the flexible substrate layer 1 is positioned at a bottom layer and attached to skin, the dielectric layer 2 is positioned at the upper surface of the flexible substrate layer 1 and connected with an electrode, the flexible piezoelectric sensor 3 collects mechanical pressure changes of an abdominal cavity and converts the mechanical pressure changes of the abdominal cavity into electrical signals, the electrical signals are transmitted to the signal processing unit through the electrode, and the flexible battery 5 is used for supplying power to the flexible piezoelectric sensor 3, the signal processing unit reads and receives intra-abdominal pressure physiological parameter data in real time, the signal processing unit is also used for processing the intra-abdominal pressure physiological parameter data, the signal processing unit comprises an amplifier, a filter and a converter, the amplifier is used for shaping and amplifying electrical signals, the filter is used for performing digital filtering on the amplified signals, noise signals are removed, the converter is used for converting the amplified signals into digital signals, the digital signals are converted into analog signals by the signal processing unit and then displayed on an LED display screen and uploaded to a His system, and the His system is used for storing the intra-abdominal pressure physiological parameter data for a long time.
Wherein, the flexible substrate layer 1 is one of polydimethylsiloxane, polyethylene terephthalate, polyimide, polyethylene or polyurethane; the dielectric layer 2 is an electric insulating material, and the dielectric layer 2 is one of polydimethylsiloxane, inorganic nano-ions, ferroelectric nano-ion barium titanate, metal nano-particle conductive fillers, conductive polymers or carbon nano-tubes; the flexible piezoelectric sensor 3 is one of lead zirconate titanate or zinc oxide which are inorganic piezoelectric materials; the active layer 4 is a carbon nanotube-based active material, a graphene-based active material, and one of silicon, zinc oxide, gallium arsenide or cadmium selenide, the elasticity of which conforms to that of the structural active material; the flexible battery 5 is a flexible thin film battery, and comprises one of a flexible lithium electronic battery, a Li-S flexible battery, a stretchable organic solar battery or a thin film fuel battery; the electrode is one of conductive non-woven fabric, copper foil or graphene.
The specific implementation process is as follows:
attaching a flexible substrate layer 1 of the epidermis electronics to the abdomen of a monitored object, wherein a flexible piezoelectric sensor 3 collects intra-abdominal pressure physiological parameter data of the monitored object in real time and converts the intra-abdominal pressure physiological parameter data into an electric signal for storage; the sensing unit is connected with the signal processing unit in a wireless Bluetooth mode, and the signal processing unit reads and receives intra-abdominal pressure data of the sensing unit in real time, processes the intra-abdominal pressure data, converts digital signals into analog signals and displays the analog signals on the LED display screen; and the signal processing unit uploads the calculation result to a His system, and the His system stores the data for a long time.
The above description is only an example of the present invention, and the common general knowledge of the technical solutions or characteristics known in the solutions is not described herein too much. It should be noted that, for those skilled in the art, without departing from the technical solution of the present invention, several variations and modifications can be made, which should also be regarded as the protection scope of the present invention, and these will not affect the effect of the implementation of the present invention and the practicability of the patent. The scope of the claims of the present application shall be determined by the contents of the claims, and the description of the embodiments and the like in the specification shall be used to explain the contents of the claims.

Claims (9)

1. The utility model provides an intra-abdominal pressure monitoring system based on epidermis electron which characterized in that: including sensing unit, signal processing unit, LED display screen and His system, the sensing unit with the signal processing unit passes through wireless bluetooth and connects, the signal processing unit with the LED display screen with His system electric connection, the sensing unit is the epidermis electron, the epidermis electron is used for gathering monitoring intra-abdominal pressure physiological parameter data and converts it into the signal of telecommunication and saves, the signal processing unit reads in real time and receives intra-abdominal pressure physiological parameter data, the signal processing unit still handles intra-abdominal pressure physiological parameter data, shows behind the digital signal conversion analog signal on the LED display screen and go up to the His system, the His system carries out long-term storage to intra-abdominal pressure physiological parameter data.
2. The intraabdominal pressure monitoring system based on epidermal electronics of claim 1, wherein: the signal processing unit comprises an amplifier, a filter and a converter, wherein the amplifier is used for shaping and amplifying an electrical signal, the filter is used for digitally filtering the amplified signal and removing a noise signal, and the converter is used for converting the amplified and filtered signal into a digital signal.
3. The intraabdominal pressure monitoring system based on epidermal electronics of claim 1, wherein: the utility model discloses a flexible piezoelectric sensor, including flexible basal layer (1), dielectric layer (2), flexible piezoelectric sensor (3), active layer (4) and flexible battery (5) from upwards including in proper order down, flexible basal layer (1) is located the bottom and pastes in skin, dielectric layer (2) are located the upper surface of flexible basal layer (1) is connected with the electrode, abdominal cavity mechanical pressure change is gathered in flexible piezoelectric sensor (3) to change abdominal cavity mechanical pressure into electrical signal, through the electrode gives electrical signal transmission the signal processing unit, flexible battery (5) are used for the power supply of flexible piezoelectric sensor (3).
4. The intraabdominal pressure monitoring system based on epidermal electronics of claim 3, wherein: the flexible substrate layer (1) is one of polydimethylsiloxane, polyethylene terephthalate, polyimide, polyethylene or polyurethane.
5. The intraabdominal pressure monitoring system based on epidermal electronics of claim 3, wherein: the dielectric layer (2) is an electric insulating material, and the dielectric layer (2) is one of polydimethylsiloxane, inorganic nano-ions, ferroelectric nano-ion barium titanate, metal nano-particle type conductive fillers, conductive polymers or carbon nano-tubes.
6. The intraabdominal pressure monitoring system based on epidermal electronics of claim 3, wherein: the flexible piezoelectric sensor (3) is one of inorganic piezoelectric material lead zirconate titanate or zinc oxide.
7. The intraabdominal pressure monitoring system based on epidermal electronics of claim 3, wherein: the active layer (4) is a carbon nanotube-based active material, a graphene-based active material, and one of silicon, zinc oxide, gallium arsenide or cadmium selenide, the elasticity of which conforms to that of the structural active material.
8. The intraabdominal pressure monitoring system based on epidermal electronics of claim 3, wherein: the flexible battery (5) is a flexible thin film battery, and comprises one of a flexible lithium electronic battery, a Li-S flexible battery, a stretchable organic solar battery or a filmed fuel battery.
9. The intraabdominal pressure monitoring system based on epidermal electronics of claim 3, wherein: the electrode is one of conductive non-woven fabric, copper foil or graphene.
CN202111298852.XA 2021-11-04 2021-11-04 Intraabdominal pressure monitoring system based on epidermis electronics Pending CN114145729A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115517682A (en) * 2022-11-25 2022-12-27 四川大学华西医院 Cognitive dysfunction prediction system based on gastrointestinal electric signals and construction method
CN116831547A (en) * 2023-06-28 2023-10-03 北京大学人民医院 Transvaginal intra-abdominal pressure measuring device and application method thereof

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CN104523368A (en) * 2014-11-25 2015-04-22 苏州能斯达电子科技有限公司 Wearable flexible electronic adhesive bandage and human body health monitoring system
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CN104523368A (en) * 2014-11-25 2015-04-22 苏州能斯达电子科技有限公司 Wearable flexible electronic adhesive bandage and human body health monitoring system
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115517682A (en) * 2022-11-25 2022-12-27 四川大学华西医院 Cognitive dysfunction prediction system based on gastrointestinal electric signals and construction method
CN115517682B (en) * 2022-11-25 2023-01-31 四川大学华西医院 Cognitive dysfunction prediction system based on gastrointestinal electric signals and construction method
CN116831547A (en) * 2023-06-28 2023-10-03 北京大学人民医院 Transvaginal intra-abdominal pressure measuring device and application method thereof

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