CN114052676B - Traditional Chinese medicine pulse simplified array sensor and full array pulse information acquisition algorithm thereof - Google Patents
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
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Abstract
The invention provides a traditional Chinese medicine pulse simple array sensor and a full array pulse information acquisition algorithm thereof. The sensor comprises a group of longitudinal sensing units (arranged along radial artery direction) and a group of transverse sensing units (arranged perpendicular to radial artery direction), and obtains longitudinal and transverse pulse beating intensity values and change rules respectively. And then calculating and acquiring the pulse intensity value of each unit of the full array at each moment according to the pulse intensity value sensed by each sensing unit at each moment and the change rule of the pulse intensity values along the longitudinal direction and the transverse direction. Therefore, the purpose of acquiring the pulse information with high spatial resolution can be achieved by adopting fewer sensing units. The invention solves the contradiction between the spatial resolution and the sensing sensitivity of other pulse array sensors. The pulse acquisition scheme with low cost, low process limit, high accuracy, good real-time performance, high spatial resolution and complete acquired information is provided.
Description
Technical Field
The invention belongs to the field of new generation information technology and pulse signal processing, and relates to an array type pulse sensor and a pulse two-dimensional dynamic image reconstruction method thereof.
Background
Along with the continuous progress of science and technology in the society, medical level and demand are continuously improved, and the traditional Chinese medicine fuses technological elements to draw great attention. The traditional Chinese medicine analyzes pulse information through pulse diagnosis, so that the health degree of a human body and the disease of a patient are diagnosed. The diagnosis mode of the traditional Chinese medicine is noninvasive, and has the advantages of low risk, low cost and high stability, so that the traditional Chinese medicine pulse diagnosis can be automatically performed by using the modern technology, and the method becomes a focus of attention.
The existing electronic pulse diagnosis instrument adopts a force-sensitive sensor, and obtains basic information such as the frequency, the intensity and the like of pulse beating by collecting pulse signals of three parts of a human body, namely a cun part, a guan part and a chi part. Firstly, the influence of the limited acquisition area and the acquisition position of the single-point sensor cannot objectively reflect pulse information, and the reliability of a diagnosis result is low; secondly, the existing array sensor cannot deploy the sensing unit with high spatial resolution and high precision because the sensing unit is influenced by physical space (more sensing units are required in smaller size), minimum process size (the maximum sensing density which can be achieved by the process in unit area) and sensor sensing mechanism (as the minimum sensing unit size is reduced, the physical characteristics of the sensing unit such as piezoresistance, piezoelectricity, capacitance, photoelectricity and the like are weakened, so that the sensitivity and precision of the sensor are reduced), and factors such as production process and the like caused by more pins and leads of the sensor, so that the diagnosis result cannot truly, accurately and comprehensively reflect pulse information; thirdly, an array sensor has been proposed that can not present a pulse two-dimensional dynamic image, although it acquires information such as "pulse width", "pulse pressure", "pulse beat law", and the like. Therefore, the traditional Chinese medicine pulse thin-array sensor and the full-array pulse information acquisition algorithm thereof have positive significance, and the traditional Chinese medicine pulse thin-array sensor is low in cost, low in process limit, high in accuracy, good in instantaneity and high in spatial resolution, and can overcome the contradiction between the spatial resolution and the sensing sensitivity required by the traditional array sensor.
Disclosure of Invention
The invention aims to overcome the contradiction between the spatial resolution and the sensing sensitivity required by the traditional array sensor, realize the reconstruction of pulse two-dimensional dynamic images, acquire the pulse signals with high spatial resolution and solve the problems of unrealistic, inaccurate and incomplete measurement positions and measurement ranges and measurement results caused by physical and technological reasons and the like in the existing pulse acquisition technology. Because the pulse has the characteristic of periodical cooperative variation and the continuity degree of the jump transmission in space is more obvious, the invention provides the thin array sensor suitable for collecting the pulse signals and the corresponding amplitude matrix operation mode, so as to realize the acquisition of the pulse signals and the two-dimensional dynamic reconstruction images thereof with high accuracy and good instantaneity along with the dynamic variation of the time phase.
The invention is realized in the following way:
the sensor comprises a group of longitudinal sensing units (arranged along the radial artery direction) and a group of transverse sensing units (arranged perpendicular to the radial artery direction), and longitudinal pulse beat information and change rules are respectively acquired; and calculating and acquiring the pulse value of each unit of the full array at each moment according to the pulse value sensed by each sensing unit at each moment and the change rule of the longitudinal and transverse values.
Specifically, the traditional Chinese medicine pulse thin-array sensor comprises a transverse sensor group and a longitudinal sensor group. The transverse sensor group is used for detecting pulse information in the direction perpendicular to the radial artery, and the longitudinal sensor group is used for collecting pulse information in the direction perpendicular to the radial artery. The sensor groups in two arrangement forms form a traditional Chinese medicine pulse thin array sensor.
Optionally, each sensing unit of the traditional Chinese medicine pulse thin-array sensor may be a pressure sensor (including a piezoresistive sensor, a piezoelectric sensor, a pressure capacitance sensor, a pressure inductance sensor, a resonant pressure sensor, etc.), or may be a photoelectric sensor (including an infrared sensor, an optical fiber sensor, a grating sensor, etc.).
Optionally, a group of longitudinal sensing units and a group of transverse sensing units in the traditional Chinese medicine pulse thin-array sensor can be arranged in a concentrated manner or two groups of alternate and dispersed manner.
Optionally, the traditional Chinese medicine pulse thin array sensor can be three independent thin arrays with smaller areas, and three pulse acquisition positions of the cun, guan and chi are respectively covered to obtain pulse information of each position; or a larger simplified array which completely covers three pulse acquisition parts of the cun, guan and chi to acquire the pulse information of the whole area.
Optionally, the traditional Chinese medicine pulse thin array sensor can divide each group of sensing units and increase the number of the sensing units under the condition that two groups of sensing units arranged in the longitudinal and transverse directions are still maintained.
Alternatively, the traditional Chinese medicine pulse thin array sensor can be prepared on a flexible substrate or a rigid or semi-rigid substrate.
Specifically, collecting pulse information, and reconstructing a pulse two-dimensional dynamic image includes:
covering radial artery with the sensor array of the traditional Chinese medicine pulse simplified array to collect pulse signals, filtering the collected signals through a filter circuit, digitally filtering the signals through an A/D (analog to digital) conversion circuit, and finally transmitting the processed signals to an upper computer;
Recording pulse wave signals of sensors with different sampling time;
normalizing the transverse sensors in the sensor array;
carrying out numerical operation on the signals of the sensor units in a period of sampling time;
acquiring a pulse signal with high spatial resolution and dynamically reconstructing a two-dimensional dynamic pulse image;
optionally, recording the pulse wave signals of the sensors at different sampling times includes:
The method comprises the steps of (1) coordinating positions of different sensors of a sensor array and recording signal amplitude values of each sensor to obtain a series of signal intensity matrixes of transverse and longitudinal sensors, wherein the signal intensity matrixes are q 1～qn and R 1～Rn respectively;
optionally, wherein the transverse sensor normalization in the sensor array comprises:
Respectively normalizing signal amplitudes of different periods of the transverse sensors of the sensor array to obtain a series of signal intensity normalization matrixes Q 1～Qn of the transverse sensors;
Optionally, the numerical operation is performed on the sensor unit signal in a sampling time:
Multiplying the diagonal matrix A of the transverse original matrix Q n and the transverse normalized matrix Q n obtained by the same pulse period in one sampling time period of the sensor to obtain a composite transverse matrix V n, and multiplying the transverse normalized matrix Q n and the longitudinal signal intensity matrix R n to obtain a composite longitudinal matrix W n;
Optionally, the reconstructing of the pulse two-dimensional dynamic image includes:
The series of signal intensity synthesis transversal matrices V n and synthesis longitudinal matrices W n are combined to form a two-dimensional image reconstruction matrix D n, wherein matrix V n reconstructs the first column of data of matrix D n.
Optionally, the pulse information obtained by the traditional Chinese medicine pulse thin array sensor can be directly used for pulse diagnosis and analysis, or can be used for pulse diagnosis and analysis after the full array pulse information is obtained through calculation.
Compared with the prior art, the invention has the beneficial effects that: the method solves the problems of low spatial resolution and low precision of the pulse sensing unit caused by physical, technological and other reasons of the sensor array, and well acquires the pulse position information and the pressure information truly, accurately and comprehensively; based on the characteristic that the pulse has periodical cooperativity change, the amplitude matrix operation mode of the sensor provided by the invention keeps the continuity degree of pulse jump transmission in space, can acquire high-spatial resolution pulse signals and realize pulse two-dimensional dynamic image reconstruction with high accuracy and good real-time along with time phase dynamic change of the pulse, thereby improving the diagnosis accuracy.
Drawings
Fig. 1 is a schematic diagram of a pulse simplified array sensor and a full array pulse information acquisition algorithm thereof in traditional Chinese medicine;
FIG. 2 is a schematic diagram showing the alternate and dispersed arrangement of sensing units of a traditional Chinese medicine pulse thin-array sensor;
FIG. 3 is a schematic diagram of a smaller thin-array sensor covering three pulse acquisition sites of the cun, guan and chi respectively and a larger thin-array sensor covering three pulse acquisition sites of the cun, guan and chi completely;
FIG. 4 is a schematic diagram of a traditional Chinese medicine pulse thin-array sensor further dividing sensing units and increasing the number of the sensing units;
fig. 5 is a flowchart of a full array pulse information acquisition algorithm of a traditional Chinese medicine pulse thin array sensor.
The figures are marked as follows:
1, a transverse sensor unit, 2, a longitudinal sensor unit, 3, a full array pulse intensity value matrix obtained after calculation, 4, an independent thin array sensor, and 5, a larger thin array sensor for completely covering three pulse acquisition positions of an inch, an off and a ruler.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. Variations, modifications, substitutions and alterations are also possible in the embodiments of this disclosure without departing from the principles of this disclosure. The embodiment of the invention provides a traditional Chinese medicine pulse simple array sensor and a full array pulse information acquisition algorithm thereof.
The sensor comprises a group of longitudinal sensing units (arranged along the radial artery direction) and a group of transverse sensing units (arranged perpendicular to the radial artery direction), and longitudinal pulse beat information and change rules are respectively acquired; and according to the pulse value sensed by each sensing unit at each moment and the change rule of the longitudinal and transverse values, calculating to obtain the pulse value of each unit of the full array at the moment. As shown in fig. 1, the sensor provided by the invention acquires longitudinal and transverse pulse beat information and change rules, and calculates to acquire pulse signals of each point in a measurement range. Wherein 1 is a transverse sensor, 2 is a longitudinal sensor, and 3 is a calculated array unit response value.
Specifically, each sensing unit of the traditional Chinese medicine pulse thin-array sensor can be a pressure sensor (including a piezoresistive sensor, a piezoelectric sensor, a pressure capacitance sensor, a pressure inductance sensor, a resonant pressure sensor and the like), or a photoelectric sensor (including an infrared sensor, an optical fiber sensor and a grating sensor).
Specifically, a group of longitudinal sensing units and a group of transverse sensing units in the traditional Chinese medicine pulse thin-array sensor can be arranged in a concentrated manner or two groups of alternate and dispersed manner. As shown in fig. 2, fig. 2 shows several designs, wherein 1 is a transverse sensor and 2 is a longitudinal sensor. Fig. 2 shows a number of possible sensor arrangements, but not all, and any basic modifications are within the scope of protection.
Specifically, in the use process, the traditional Chinese medicine pulse thin array sensor can also be three independent thin arrays with smaller areas, and three pulse acquisition positions of an inch, a close and a ruler are respectively covered to obtain pulse information of each position; or a larger simplified array can be used for completely covering three pulse acquisition positions of the cun, guan and chi to acquire the pulse information of the whole area, as shown in fig. 3. Wherein 4 represents three independent thin arrays, and 5 is a larger thin array.
The traditional Chinese medicine pulse thin array sensor can divide each group of sensing units and increase the number of the sensing units under the condition that two groups of sensing units which are arranged in the longitudinal and transverse directions are still maintained. As shown in fig. 4, a special partitioning scheme is shown in fig. 2d as partitioned into fig. 4b, but not all partitioning schemes are represented. In the figure, a longitudinal sensor is shown at 1, and a transverse sensor is shown at 2.
Specifically, pulse signals of each point in the measurement range are acquired through the traditional Chinese medicine pulse thin array sensor, and a two-dimensional pulse image reconstruction process is shown in fig. 5, and comprises the following steps:
S81, signal acquisition and processing.
Specifically, the pulse simplifying array sensor of the traditional Chinese medicine is covered with radial artery to collect pulse signals, the collected signals are filtered through a filter circuit, then are subjected to digital filtering through an A/D (analog to digital) conversion circuit, and finally the processed signals are transmitted to an upper computer; the method can improve the quality of the signal.
A schematic diagram of the arrangement of the sensors is shown in fig. 1. As shown in fig. 1, the transverse sensor and the longitudinal sensor are respectively used for acquiring pulse information perpendicular to the radial artery direction and along the radial artery direction. Wherein, the sensor is a pressure sensor (including a piezoresistive sensor, a piezoelectric sensor, a pressure capacitance sensor, a pressure inductance sensor, a resonant pressure sensor and the like), or a photoelectric sensor (including an infrared sensor, an optical fiber sensor and a grating sensor). And the array sensor is fabricated on a flexible substrate, or on a rigid or semi-rigid substrate.
The sensor arrangement in the traditional Chinese medicine pulse thin array sensor can be modified according to specific requirements, as shown in fig. 2-4.
S82, recording pulse wave signals of sensors with different sampling times;
in particular, in order to facilitate signal processing, the invention marks the sensors at different positions in the sensor array with corresponding coordinates. Optionally, the coordinates of different sensor positions of the traditional Chinese medicine pulse thin array sensor can be achieved:
The signal amplitude of each sensor is recorded, and a series of signal intensity matrixes of the transverse sensor and the longitudinal sensor are obtained according to the period, wherein the signal intensity matrixes are q 1～qn and R 1～Rn respectively;
The nth cycle:
the transverse sensor signal strength matrix q n is:
The longitudinal sensor signal strength matrix R n is:
[R1(t) R2(t)...R6(t) R7(t)] (3)
The longitudinal sensor is a connected longitudinal sensing unit, if the longitudinal sensing unit is divided, signal intensity matrix averaging processing can be adopted, a matrix similar to that shown in the step (3) can be obtained, and subsequent calculation can be continued.
S83, normalizing the transverse sensors in the sensor array;
optionally, in order to realize the integrity of pulse width information of different people, the invention adopts a weight calculation mode, namely a normalization method to preprocess the signals of the transverse sensors, and the signal amplitude after normalization of each sensor in the sensor array forms a normalized amplitude matrix Q n:
The invention utilizes the signal amplitude variation of the transverse sensor in the sensor array within a period of sampling time (more than one pulse period) to obtain a series of normalized signal amplitudes to form a normalized amplitude matrix Q 1～Qn.
S84, carrying out numerical operation on the signal of the sensor unit in a period of sampling time;
Multiplying the diagonal matrix A of the transverse original matrix Q n and the transverse normalized matrix Q n obtained by the same pulse period in one sampling time period of the sensor to obtain a composite transverse matrix V n, and multiplying the transverse normalized matrix Q n and the longitudinal signal intensity matrix R n to obtain a composite longitudinal matrix W n;
S85, acquiring high-spatial resolution pulse information, and reconstructing a pulse two-dimensional dynamic image;
Optionally, the pulse two-dimensional dynamic image reconstruction is performed, and the series of signal intensity synthesis transverse matrix V n and synthesis longitudinal matrix W n are combined to form a two-dimensional image reconstruction matrix D n, where matrix V n and matrix W n are the block matrices of reconstruction matrix D n (matrix V n is the first column number of reconstruction matrix D n).
Claims (4)
1. A traditional Chinese medicine pulse simple array sensor is characterized in that: the simplified array sensor consists of a group of longitudinal sensing units and a group of transverse sensing units, wherein the longitudinal sensing units are arranged along the radial artery direction, the transverse sensing units are arranged along the direction vertical to the radial artery direction, and longitudinal pulse beating intensity values and change rules are respectively obtained; according to the pulse intensity values sensed by the sensing units at each moment and the change rule of the pulse intensity values along the longitudinal direction and the transverse direction, the pulse intensity values of the units of the full array at a certain moment are obtained through calculation, a two-dimensional pulse intensity array is formed, and two-dimensional pulse image reconstruction can be achieved;
Wherein, the arrangement mode of the group of longitudinal sensing units and the group of transverse sensing units is that each group is arranged in a concentrated way or the two groups are alternately arranged in a dispersed way;
In the using process, the traditional Chinese medicine pulse thin array sensor is three independent thin arrays with small areas, and three pulse acquisition positions of an inch, a close and a ruler are respectively covered to acquire pulse information of each position; or a large thin array which completely covers three pulse acquisition positions of the cun, guan and chi to acquire the pulse information of the whole area;
the arrangement mode of the group of longitudinal sensing units and the group of transverse sensing units can divide the groups of sensing units and increase the number of the sensing units under the condition that two groups of sensing units arranged in the longitudinal and transverse directions are still maintained;
Different sensing units cover all radial arteries and peripheral areas thereof, the pulse intensity information of each point of a pulse acquisition area is obtained according to the signal intensity of each sensing unit and the change rule of the longitudinal and transverse intensities, a two-dimensional dynamic numerical matrix, namely full-array pulse information is formed, so that the pulse information with high spatial resolution of the pulse acquisition area is obtained,
The algorithm for acquiring the pulse intensity information of each point of the pulse acquisition area comprises the following steps:
1-1, signal acquisition and processing;
1-2 recording pulse signals of sensor units with different sampling time;
1-3 normalizing pulse intensity values at each moment of a transverse sensor unit in a sensor array;
1-4, carrying out numerical operation on the signals of the sensor units within a period of sampling time;
1-5, acquiring high spatial resolution pulse information at each moment to form a two-dimensional dynamic numerical matrix;
Wherein the signal acquisition and processing includes: the sensor array covers radial artery and peripheral area thereof to obtain response values of each sensing unit, the acquired response values are filtered and amplified by a circuit, and then analog-digital conversion is carried out by an A/D conversion circuit, and finally pulse intensity values corresponding to each sensing unit are obtained;
Wherein recording pulse signals of different sensor units over a sampling time comprises: the method comprises the steps of coordinating positions of different sensor units of a sensor array, and recording pulse intensity values of each sensor unit at each moment to obtain a series of signal intensity values of transverse and longitudinal sensor units;
Wherein normalizing the pulse intensity values for each instant of time of the lateral sensor units in the sensor array comprises: respectively normalizing signal amplitudes of different periods of the transverse sensors of the sensor array to obtain a series of signal intensity normalization matrixes of the transverse sensors;
wherein the numerical operation on the sensor unit signal in a sampling period comprises: the diagonal matrix of the transverse original matrix is obtained by utilizing the same pulse period of the sensor within a period of sampling time, the transverse normalized matrix is multiplied to obtain a synthesized transverse matrix, and the longitudinal signal intensity matrix and the transverse normalized matrix are synthesized into a longitudinal matrix;
Wherein obtaining the high spatial resolution pulse information at each instant to form a two-dimensional dynamic numerical matrix comprises: and combining a series of signal intensity synthesis transverse matrixes and synthesis longitudinal matrixes to obtain high-spatial resolution pulse information, so as to form full-array pulse dynamic information, namely a two-dimensional pulse dynamic image.
2. The traditional Chinese medicine pulse thin array sensor according to claim 1, wherein: the sensor units of the traditional Chinese medicine pulse thin-array sensor are pressure sensors or photoelectric sensors, wherein the pressure sensors comprise piezoresistive sensors, piezoelectric sensors, pressure capacitance sensors, pressure inductance sensors and resonant pressure sensors, and the photoelectric sensors comprise infrared sensors, optical fiber sensors and grating sensors.
3. The traditional Chinese medicine pulse thin array sensor according to claim 1, wherein: the traditional Chinese medicine pulse thin array sensor is prepared on a flexible substrate or a rigid or semi-rigid substrate.
4. The traditional Chinese medicine pulse thin array sensor according to claim 1, wherein: the pulse information obtained by the traditional Chinese medicine pulse thin array sensor is directly used for pulse diagnosis and analysis, or the pulse information obtained by the whole array is calculated and then used for pulse diagnosis and analysis.
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