CN114018985A - Biological virus concentration detector based on internet of things technology - Google Patents
Biological virus concentration detector based on internet of things technology Download PDFInfo
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- CN114018985A CN114018985A CN202111294371.1A CN202111294371A CN114018985A CN 114018985 A CN114018985 A CN 114018985A CN 202111294371 A CN202111294371 A CN 202111294371A CN 114018985 A CN114018985 A CN 114018985A
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- 241000700605 Viruses Species 0.000 title claims abstract description 56
- 238000005516 engineering process Methods 0.000 title claims abstract description 25
- 238000006243 chemical reaction Methods 0.000 claims abstract description 66
- 230000001737 promoting effect Effects 0.000 claims abstract description 46
- 238000001514 detection method Methods 0.000 claims abstract description 38
- 229920006300 shrink film Polymers 0.000 claims description 22
- 239000007788 liquid Substances 0.000 claims description 16
- 239000003094 microcapsule Substances 0.000 claims description 16
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 15
- 230000001939 inductive effect Effects 0.000 claims description 15
- 239000011521 glass Substances 0.000 claims description 13
- 239000000758 substrate Substances 0.000 claims description 13
- 230000005489 elastic deformation Effects 0.000 claims description 9
- 238000007789 sealing Methods 0.000 claims description 8
- 239000010931 gold Substances 0.000 claims description 6
- 229910052737 gold Inorganic materials 0.000 claims description 6
- 241001465754 Metazoa Species 0.000 abstract description 13
- 238000001556 precipitation Methods 0.000 abstract description 5
- 239000000243 solution Substances 0.000 description 33
- 239000000284 extract Substances 0.000 description 16
- 238000010586 diagram Methods 0.000 description 7
- 230000000694 effects Effects 0.000 description 7
- 230000009471 action Effects 0.000 description 4
- 230000008676 import Effects 0.000 description 4
- 239000002244 precipitate Substances 0.000 description 4
- 230000005611 electricity Effects 0.000 description 3
- 238000000605 extraction Methods 0.000 description 3
- 239000000419 plant extract Substances 0.000 description 3
- 230000008602 contraction Effects 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 241000711573 Coronaviridae Species 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000010460 detection of virus Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 238000004880 explosion Methods 0.000 description 1
- JUWSSMXCCAMYGX-UHFFFAOYSA-N gold platinum Chemical compound [Pt].[Au] JUWSSMXCCAMYGX-UHFFFAOYSA-N 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
Abstract
The invention discloses a biological virus concentration detector based on the technology of Internet of things, belonging to the field of virus detection, and the biological virus concentration detector based on the technology of Internet of things comprises a micro-fluidic chip arranged in a detector body, a detector control system is arranged in the detector body, the detector control system comprises a central controller, the output end of the central controller is respectively and electrically connected with a display module and a mobile terminal through leads, the input end of the central controller is respectively connected with a power module and a detection module through leads, the automatic detection of the virus concentration carried by animals and plants can be realized through the matching of the detector control system and a reaction promoting tube, the flow speed of an extracting solution in a channel layer can be effectively promoted, the combination efficiency of viruses and antibody solution in the extracting solution can be further improved, the reaction precipitation time can be reduced, and the detection efficiency of the biological virus concentration can be further improved, promotes the development and application of biological virus detection technology.
Description
Technical Field
The invention relates to the field of virus detection, in particular to a biological virus concentration detector based on the technology of the Internet of things.
Background
With the continuous development of globalization, the import and export trade in China is developed comprehensively, but under the current big environment of new coronavirus, how to ensure the safety of import and export animals and plants is a common concern of the current nations, so that a portable, rapid and effective biological virus concentration detector can be developed and applied, virus detection can be carried out on the import and export animals and plants, and the safety of the import and export trade is improved.
The biological virus concentration detector mainly utilizes a micro-fluidic impedance detection principle, is based on micro-fluidic impedance detection characteristics, adopts a micro-fluidic chip embedded with gold interdigital microelectrodes as a detection platform, builds a set of micro-fluidic impedance chip detection and analysis system, detects the concentration of biological viruses, and achieves the effects of quick, convenient and effective detection.
When the concentration of viruses carried by animals and plants is detected by the biological virus concentration detector in the prior art, the extracting solution is drained to the microfluidic chip through the injection pump, and data detection is carried out on the combination of the viruses and the antibody solution in the extracting solution, but after the extracting solution is injected into the microfluidic chip in the detection process, the combination of the viruses and the antibody solution in the extracting solution mainly depends on the natural mobility of liquid, so that the efficiency of generating precipitates between the viruses and the antibody solution is greatly reduced, the biological virus concentration detection time is longer, and the development and the application of a biological virus detection technology are not facilitated.
Disclosure of Invention
1. Technical problem to be solved
Aiming at the problems in the prior art, the invention aims to provide a biological virus concentration detector based on the internet of things technology, which can realize automatic detection of the concentration of viruses carried by animals and plants through the cooperation of a detector control system and a promotion reaction tube, and effectively promote the flow speed of an extracting solution in a channel layer, so that the combination efficiency of viruses and an antibody solution in the extracting solution is improved, the reaction precipitation time is shortened, the biological virus concentration detection efficiency is improved, and the development and application of a biological virus detection technology are promoted.
2. Technical scheme
In order to solve the above problems, the present invention adopts the following technical solutions.
A biological virus concentration detector based on the Internet of things technology comprises a detector body, wherein a micro-fluidic chip is installed in the detector body, a detector control system is arranged in the detector body and comprises a central controller, the output end of the central controller is electrically connected with a display module and a mobile terminal through leads respectively, the input end of the central controller is connected with a power supply module and a detection module through leads respectively, an impedance sensor is arranged in the detection module, and the impedance sensor is in limited connection with the micro-fluidic chip through leads;
the micro-fluidic chip comprises a glass substrate, the glass substrate is connected to the detector body in a sliding mode, a channel layer is fixedly connected to the glass substrate, a plurality of reaction promoting tubes are fixedly connected to the left inner wall and the right inner wall of the channel layer, a plurality of reaction promoting hemispherical grooves corresponding to the reaction promoting tubes are formed in the left inner wall and the right inner wall of the channel layer, the contraction films are fixedly connected to the inside of the reaction promoting hemispherical grooves in a stacking mode, automatic detection of virus concentration carried by animals and plants is achieved through cooperation of a detector control system and the reaction promoting tubes, meanwhile, the flowing speed of an extracting solution on the channel layer is effectively promoted, the efficiency of combination of viruses and antibody solution in the extracting solution is improved, the reaction precipitation time is shortened, the detection efficiency of biological virus concentration is improved, and the development and application of a biological virus detection technology are promoted.
Further, pile up and seted up a plurality of bleeder vents on the shrink film, fixedly connected with pellicle in the bleeder vent, when piling up the shrink film and producing and being in normal contraction state, its inside bleeder vent is not logical, and then keeps the normal flow of extract, effectively avoids palirrhea of extract, produces the inflation piling up the shrink film for the bleeder vent is not piled up, and then can pour into the air current into in the passageway layer, promotes the flow of extract, improves the suitability of piling up the shrink film.
Furthermore, the inner wall of one side, far away from the stacked shrink film, of the reaction promoting pipe is fixedly connected with a shrink microcapsule, one side, close to the stacked shrink film, of the shrink microcapsule is fixedly connected with a flexible sealing sheet, and the flexible sealing sheet is in sliding connection with the reaction promoting pipe.
Furthermore, a plurality of elastic deformation wires are fixedly connected in the shrinkage micro-capsule, and a plurality of inductive reactor balls are fixedly connected to the elastic deformation wires.
Furthermore, the output end of the central controller is also connected with a promoting reaction module, the output end of the promoting reaction module is electrically connected with the inductive reactor ball through a lead, the inductive reactor ball is controlled to be powered on and powered off through the promoting reaction module, the inductive reactor ball is enabled to generate power-on tension, the volume form of power failure recovery is realized, and then the shrinkage microcapsules are enabled to generate expansion shrinkage actions, the extracting solution can be promoted when the shrinkage microcapsules are effectively intermittent, the flow rate of the extracting solution is improved, the reaction of viruses in the extracting solution can be effectively waited while the reaction efficiency is improved, and effective time is reserved for the generation of precipitates.
Furthermore, a gold foil electrode group is fixedly connected to the middle of the channel layer, a gold fork array reaction chamber is arranged in the gold foil electrode group, a cover plate layer is clamped at the upper end of the glass substrate, and the cover plate layer is located on the outer side of the channel layer.
Furthermore, the left end of the channel layer is a liquid inlet, the right end of the channel layer is a liquid outlet, the gold fork array reaction chamber is located between the liquid inlet and the liquid outlet, the promoting reaction tubes are obliquely arranged towards the direction of the liquid outlet, the inclination angle is 25-45 degrees, the promoting reaction tubes which are obliquely arranged can effectively guide the extracting solution, and the promoting effect is improved.
Furthermore, a power input module, a battery charging module, a rechargeable battery and a 3V low exit regulator are arranged in the power module, a power interface is arranged at the front end of the detector body, the power input module is electrically connected with the power interface through a wire, the input end of the central controller is further connected with a battery capacity feedback module, and the input end of the battery capacity feedback module is electrically connected with the rechargeable battery through a wire.
Furthermore, the output end of the central controller is also connected with a power consumption Bluetooth module.
Furthermore, the detector body is of a rectangular structure, is a cuboid with the length of 5-20cm, the width of 5-15cm and the thickness of 5-10cm, is small and portable, has high detection efficiency, is beneficial to development and application of a biological virus detection technology, and improves safety of animal and plant trade.
3. Advantageous effects
Compared with the prior art, the invention has the advantages that:
(1) the scheme has the advantages that through the matching of the detector control system and the promotion reaction tube, the automatic detection of the virus concentration carried by animals and plants is realized, meanwhile, the flowing speed of the extracting solution on a channel layer is effectively promoted, the combination efficiency of the virus and the antibody solution in the extracting solution is further improved, the reaction precipitation time is reduced, the biological virus concentration detection efficiency is improved, and the development and the application of a biological virus detection technology are promoted.
(2) When piling up the shrink film and producing and being in normal shrink state, its inside bleeder vent is not logical, and then keeps the normal flow of extract, effectively avoids palirrhea of extract, piles up the shrink film and produces the inflation for the bleeder vent is not piled up, and then can be to the intraformational air current of infusing of passageway, promotes the flow of extract, improves the suitability that piles up the shrink film.
(3) Make through promoting the break-make electricity of reaction module control inductance reactor ball for inductance reactor ball produces the logical electricity and spouts the tension, and the volume form that the outage resumes, and then makes the shrink microcapsule produce the inflation shrinkage action, carries out the promotion effect to the extract when can effectively intermittent type, improves the extract velocity of flow, when improving reaction efficiency, can also effectively wait for the reaction of virus in the extract, remains effectual time for the production of precipitate.
(4) The promotion reaction tube that the slope set up can carry out effective guide to the extract, improves the promotion effect.
Drawings
FIG. 1 is a schematic view of an axial structure of the present invention;
FIG. 2 is a schematic diagram of the framework of the control system of the inspection apparatus of the present invention;
FIG. 3 is a schematic diagram of an exploded structure of a microfluidic chip according to the present invention;
FIG. 4 is a schematic view of an axial structure of a channel layer according to the present invention;
FIG. 5 is a schematic top view of the channel layer of the enhanced reaction tube of the present invention;
FIG. 6 is a schematic diagram of the structure at A of FIG. 5 in accordance with the present invention;
FIG. 7 is a schematic diagram of the explosion structure of the microfluidic chip in the reaction-promoting tube of the present invention;
FIG. 8 is a schematic view of the channel layer structure in the reaction-promoting tube according to the present invention;
FIG. 9 is a schematic top view of the channel layer for promoting the reaction tube according to the present invention;
FIG. 10 is a schematic view of the structure of FIG. 9 at B in accordance with the present invention;
FIG. 11 is a schematic diagram of a circuit configuration of a central controller according to the present invention;
FIG. 12 is a schematic diagram of a circuit structure of a detection module according to the present invention;
FIG. 13 is a schematic diagram of a power circuit of a display module according to the present invention;
the reference numbers in the figures illustrate:
the device comprises a detector body 1, a microfluidic chip 2, a glass substrate 201, a cover plate layer 202, a channel layer 203, a 2031 half sphere groove promoting device, a gold foil electrode group 204, a gold fork array reaction chamber 205, a reaction promoting tube 3, a flexible sealing sheet 301, a shrinkage film 4, a shrinkage microcapsule 5, an elastic deformation wire 6 and an inductive reactor sphere 601.
Detailed Description
The technical solution in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention; it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments, and all other embodiments obtained by those skilled in the art without any inventive work are within the scope of the present invention.
In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "top/bottom", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and thus should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "disposed," "sleeved/connected," "connected," and the like are to be construed broadly, e.g., "connected," which may be fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
Example 1:
referring to fig. 1-13, a biological virus concentration detector based on internet of things technology comprises a detector body 1, a microfluidic chip 2 is installed in the detector body 1, a detector control system is arranged in the detector body 1, the detector control system comprises a central controller, an output end of the central controller is respectively and electrically connected with a display module and a mobile terminal through leads, an input end of the central controller is respectively connected with a power module and a detection module through leads, an impedance sensor is arranged in the detection module, an emitter of the impedance sensor (type: ad5933) comprises a 27-phase accumulator core, which provides an output excitation signal at a specific frequency, a receiver is composed of a current-voltage amplifier, a Programmable Gain Amplifier (PGA) and an anti-aliasing filter, and generates a signal through the emitter to excite external complex impedance, the response signal of the external impedance is sampled by the ADC, then the DFP processing is carried out by the DSP to obtain an impedance value, the impedance sensor is connected with the micro-fluidic chip 2 in a limiting way through a lead, and the impedance sensor is electrically connected with the micro-fluidic chip 2 through a conductive clamp; the gold foil electrode group 204 on the micro-fluidic chip 2 is contacted through the conductive clip and generates exciting current, the analog quantity of the impedance value is obtained through signal feedback, then the analog quantity is converted into digital quantity and substituted into a corresponding formula of the impedance value and the virus concentration to obtain a concentration value, the detection module feeds back the concentration value to the central controller, and the central controller transmits the result to the display module and the mobile terminal.
Referring to fig. 1-10, the microfluidic chip 2 includes a glass substrate 201, the glass substrate 201 is slidably connected in the detector body 1, the upper end of the glass substrate 201 is fixedly connected with a channel layer 203, the left inner wall and the right inner wall of the channel layer 203 are both fixedly connected with a plurality of reaction promoting tubes 3, a plurality of promoting hemisphere grooves 2031 corresponding to the promoting reaction tubes 3 are arranged on the left and right inner walls of the channel layer 203, the promoting hemisphere groove 2031 is internally and fixedly connected with a stack shrink film 4, and through the matching of a detector control system and the promoting reaction tube 3, the concentration of the virus carried by animals and plants can be automatically detected, the flowing speed of the extracting solution in the channel layer 203 can be effectively promoted, further improving the combination efficiency of the virus in the extracting solution and the antibody solution, reducing the time of reaction precipitation, improving the detection efficiency of the biological virus concentration and promoting the development and application of the biological virus detection technology.
Referring to fig. 6 and 10, a plurality of air holes are formed in the stacked shrink film 4, a semi-permeable film is fixedly connected to the air holes, when the stacked shrink film 4 is in a normal shrink state, the air holes in the stacked shrink film are not communicated, so that the normal flow of the extracting solution is maintained, the reverse flow of the extracting solution is effectively avoided, the stacked shrink film 4 is expanded, the air holes are not stacked, air flow can be injected into the channel layer 203, the flow of the extracting solution is promoted, and the applicability of the stacked shrink film 4 is improved.
Referring to fig. 6 and 10, the inner wall of the reaction promoting tube 3 away from the stacked shrink film 4 is fixedly connected with a shrink microcapsule 5, the side of the shrink microcapsule 5 close to the stacked shrink film 4 is fixedly connected with a flexible sealing sheet 301, and the flexible sealing sheet 301 is slidably connected with the reaction promoting tube 3. Referring to fig. 6 and 10, a plurality of elastic deformation wires 6 are fixedly connected in the contracted microcapsules 5, and a plurality of inductive reactor balls 601 are fixedly connected to the elastic deformation wires 6. Referring to fig. 1 to 13, the output end of the central controller is further connected to a reaction promoting module, the output end of the reaction promoting module is electrically connected to the inductive reactor sphere 601 through a wire, and the reaction promoting module controls the inductive reactor sphere 601 to be powered on and off, so that the inductive reactor sphere 601 generates a volume form of power on and off recovery, and further the shrinkage microcapsule 5 generates an expansion and shrinkage action, so that the extraction solution can be promoted in an effective intermittent manner, the flow rate of the extraction solution is increased, the reaction efficiency is improved, and meanwhile, the reaction of viruses in the extraction solution can be effectively waited, and an effective time is reserved for the generation of precipitates.
Referring to fig. 4-10, a gold foil electrode group 204 is fixedly connected to the middle of the channel layer 203, the gold foil electrode group 204 is composed of three gold platinum electrodes, a gold fork array reaction chamber 205 is disposed in the gold foil electrode group 204, a cover sheet layer 202 is clamped to the upper end of the glass substrate 201, and the cover sheet layer 202 is located outside the channel layer 203. Referring to fig. 4 to 10, the left end of the channel layer 203 is a liquid inlet, the right end of the channel layer 203 is a liquid outlet, the gold-fork array reaction chamber 205 is located between the liquid inlet and the liquid outlet, the plurality of reaction promoting tubes 3 are all inclined toward the liquid outlet, the inclination angle is 25 to 45 degrees, and the inclined reaction promoting tubes 3 can effectively guide the extracting solution, thereby improving the promoting effect.
Referring to fig. 1-13, after the animal and plant extract is added into the channel layer 203, the reaction promoting module controls the inductive reactor sphere 601 to be powered on first, at this time, the inductive reactor sphere 601 generates inductive reaction expansion to drive the elastic deformation filament 6 to extend, so as to expand the volume of the shrinkage microcapsule 5, further push the flexible sealing sheet 301 to move in the reaction promoting tube 3 toward the stacked shrinkage film 4, pressurize the gas in the hemispherical groove 2031, so as to expand the stacked shrinkage film 4, open the air vent, further convey the gas into the channel layer 203, accelerate the flow of the animal and plant extract, so that the animal and plant extract can rapidly enter the gold-fork array reaction chamber 205 for reaction, and simultaneously inject bubbles into the extract, so that the bubbles burst during the reaction of the extract to generate vibration, thereby improving the diffusivity of the extract, further shortening the reaction time, and then control the inductive reactor sphere 601 to be powered off, make it produce the outage and resume, and improve the speed that shrink microcapsule 5 resumes deformation under the effect of elastic deformation silk 6, the efficiency of the effect of promotion reaction tube 3 is improved, flexible mounting 301 is keeping away from in promoting reaction tube 3 towards piling up shrink film 4 direction and removing this moment, adsorb the gas in promoting hemisphere groove 2031, make and pile up shrink film 4 shrink and pile up, block up the venthole, effectively avoid the palirrhea of extract, improve the normal action nature of extract, so relapse, make flexible mounting 301 move in promoting reaction tube 3 repeatedly, form the intermittent type control to the extract, and then when guaranteeing the reaction effect, improve reaction efficiency.
Referring to fig. 2, a power input module, a battery charging module, a rechargeable battery and a 3V low exit regulator are arranged in the power module, a power interface is arranged at the front end of the detector body 1, the power input module is electrically connected with the power interface through a wire, the input end of the central controller is further connected with a battery capacity feedback module, and the input end of the battery capacity feedback module is electrically connected with the rechargeable battery through a wire. Referring to fig. 2, the output end of the central controller is further connected to a bluetooth module. The parameters of the power input module are voltage stabilization, 5V and direct current; the parameters of the battery charging module are 5V, direct current and 1/10A; the rechargeable battery is used for storing and discharging electricity, and the capacity depends on the volume of the rechargeable battery, and is generally 30-200 mAh; the 3V low dropout regulator is used for charge control and the potential difference is cut off at less than 3V.
Referring to fig. 1, the detector body 1 is a rectangular structure, and the detector body 1 is a cuboid with a length of 5-20cm, a width of 5-15cm and a thickness of 5-10cm, and the detector body 1 is small, portable and has high detection efficiency, thereby facilitating development and application of biological virus detection technology and improving safety of animal and plant trade.
The foregoing is only a preferred embodiment of the present invention; the scope of the invention is not limited thereto. Any person skilled in the art should be able to cover the technical scope of the present invention by equivalent or modified solutions and modifications within the technical scope of the present invention.
Claims (10)
1. The utility model provides a biological virus concentration detector based on internet of things, includes detector body (1), its characterized in that: the detector comprises a detector body (1), a micro-fluidic chip (2) is installed in the detector body (1), a detector control system is arranged in the detector body (1), the detector control system comprises a central controller, the output end of the central controller is electrically connected with a display module and a mobile terminal through leads respectively, the input end of the central controller is connected with a power module and a detection module through leads respectively, an impedance sensor is arranged in the detection module, and the impedance sensor is in limited connection with the micro-fluidic chip (2) through leads;
the micro-fluidic chip (2) comprises a glass substrate (201), the glass substrate (201) is connected to the detector body (1) in a sliding mode, a channel layer (203) is fixedly connected to the upper end of the glass substrate (201), a plurality of promoting reaction tubes (3) are fixedly connected to the left inner wall and the right inner wall of the channel layer (203), a plurality of promoting hemispherical grooves (2031) corresponding to the promoting reaction tubes (3) are formed in the left inner wall and the right inner wall of the channel layer (203), and shrinkage films (4) are stacked and fixedly connected to the inner portions of the promoting hemispherical grooves (2031).
2. The biological virus concentration detector based on the internet of things technology as claimed in claim 1, wherein: a plurality of air holes are formed in the stacked shrink film (4), and semipermeable films are fixedly connected in the air holes.
3. The biological virus concentration detector based on the internet of things technology as claimed in claim 1, wherein: the inner wall of one side, far away from the stacked shrink film (4), of the reaction promoting pipe (3) is fixedly connected with a shrink microcapsule (5), one side, close to the stacked shrink film (4), of the shrink microcapsule (5) is fixedly connected with a flexible sealing sheet (301), and the flexible sealing sheet (301) is in sliding connection with the reaction promoting pipe (3).
4. The biological virus concentration detector based on the internet of things technology as claimed in claim 3, wherein: a plurality of elastic deformation wires (6) are fixedly connected in the shrinkage micro-capsule (5), and a plurality of inductive reactor balls (601) are fixedly connected on the elastic deformation wires (6).
5. The biological virus concentration detector based on the technology of the internet of things according to claim 4, wherein: the output end of the central controller is also connected with a reaction promoting module, and the output end of the reaction promoting module is electrically connected with an inductive reactor ball (601) through a lead.
6. The biological virus concentration detector based on the internet of things technology as claimed in claim 1, wherein: the middle of the channel layer (203) is fixedly connected with a gold foil electrode group (204), a gold fork array reaction chamber (205) is arranged in the gold foil electrode group (204), the upper end of the glass substrate (201) is clamped with a cover plate layer (202), and the cover plate layer (202) is positioned on the outer side of the channel layer (203).
7. The biological virus concentration detector based on the internet of things technology as claimed in claim 6, wherein: the left end of the channel layer (203) is a liquid inlet, the right end of the channel layer (203) is a liquid outlet, the golden fork array reaction chamber (205) is located between the liquid inlet and the liquid outlet, and the plurality of the reaction promoting tubes (3) are obliquely arranged towards the direction of the liquid outlet, and the inclination angle is 25-45 degrees.
8. The biological virus concentration detector based on the internet of things technology as claimed in claim 1, wherein: the detector is characterized in that a power input module, a battery charging module, a rechargeable battery and a 3V low exit regulator are arranged in the power module, a power interface is arranged at the front end of the detector body (1), the power input module is electrically connected with the power interface through a wire, the input end of the central controller is further connected with a battery capacity feedback module, and the input end of the battery capacity feedback module is electrically connected with the rechargeable battery through a wire.
9. The biological virus concentration detector based on the internet of things technology as claimed in claim 1, wherein: the output end of the central controller is also connected with a power consumption Bluetooth module.
10. The biological virus concentration detector based on the internet of things technology as claimed in claim 1, wherein: the detector body (1) is of a rectangular structure, and the detector body (1) is a cuboid with the length of 5-20cm, the width of 5-15cm and the thickness of 5-10 cm.
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| CN202111294371.1A CN114018985A (en) | 2021-11-03 | 2021-11-03 | Biological virus concentration detector based on internet of things technology |
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| WO2003102218A2 (en) * | 2002-06-03 | 2003-12-11 | Arizona Board Of Regents | Hybrid microcantilever sensors |
| US20040194534A1 (en) * | 2002-06-03 | 2004-10-07 | Porter Timothy L. | Hybrid microcantilever sensors |
| CN1700006A (en) * | 2005-04-18 | 2005-11-23 | 重庆工学院 | Avian influenza virus piezoelectric biological sensor detecting instrument |
| US20080123466A1 (en) * | 2006-11-28 | 2008-05-29 | Tylerville Technologies Llc | Dispenser with dynamic mixer for two-part compositions |
| CN107073808A (en) * | 2014-11-25 | 2017-08-18 | 日本写真印刷株式会社 | Antiviral property transfer sheet and its manufacture method and antiviral property shrinkable film and its manufacture method |
| US20180310553A1 (en) * | 2014-11-25 | 2018-11-01 | Nissha Printing Co., Ltd. | Antiviral transfer sheet and method for manufacturing same, and antiviral shrink film and method for manufacturing same |
| CN110988087A (en) * | 2019-11-25 | 2020-04-10 | 中国计量大学 | Microfluidic impedance type biological online detection device |
| CN111942994A (en) * | 2020-07-16 | 2020-11-17 | 中国计量大学 | Automatic traction steel wire rope tension adjusting device based on hydraulic pressure and valve block |
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