CN114015557B - Semi-automatic extraction device for novel coronal nucleic acid sample - Google Patents
Semi-automatic extraction device for novel coronal nucleic acid sample Download PDFInfo
- Publication number
- CN114015557B CN114015557B CN202111429024.5A CN202111429024A CN114015557B CN 114015557 B CN114015557 B CN 114015557B CN 202111429024 A CN202111429024 A CN 202111429024A CN 114015557 B CN114015557 B CN 114015557B
- Authority
- CN
- China
- Prior art keywords
- rod
- sample
- test tube
- sliding seat
- fixedly arranged
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 150000007523 nucleic acids Chemical class 0.000 title claims abstract description 25
- 102000039446 nucleic acids Human genes 0.000 title claims abstract description 25
- 108020004707 nucleic acids Proteins 0.000 title claims abstract description 25
- 238000000605 extraction Methods 0.000 title claims abstract description 21
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 14
- 229920001971 elastomer Polymers 0.000 claims description 14
- 229910052742 iron Inorganic materials 0.000 claims description 7
- 239000002985 plastic film Substances 0.000 claims description 4
- 210000003811 finger Anatomy 0.000 claims description 3
- 230000001360 synchronised effect Effects 0.000 claims description 3
- 210000003813 thumb Anatomy 0.000 claims description 3
- 230000008859 change Effects 0.000 claims description 2
- 238000000034 method Methods 0.000 description 7
- 241000711573 Coronaviridae Species 0.000 description 6
- 230000002349 favourable effect Effects 0.000 description 5
- 230000008569 process Effects 0.000 description 5
- 206010011409 Cross infection Diseases 0.000 description 3
- 206010029803 Nosocomial infection Diseases 0.000 description 3
- 230000009471 action Effects 0.000 description 3
- 230000001737 promoting effect Effects 0.000 description 3
- 230000006978 adaptation Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000009434 installation Methods 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 238000001179 sorption measurement Methods 0.000 description 2
- 238000001125 extrusion Methods 0.000 description 1
- 229920001821 foam rubber Polymers 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
Landscapes
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The invention discloses a novel crown nucleic acid sample semiautomatic extraction device, which belongs to the field of nucleic acid sample extraction, and the novel crown nucleic acid sample semiautomatic extraction device is characterized in that a transversely arranged square rod is connected inside a sliding seat in a sliding manner, the sliding seat is sleeved outside a vertical frame arranged vertically in a sliding manner, sample test tubes on a test tube rack can be extracted one by matching with the conveying of a conveying assembly, a guy cable is connected between two clamping jaws hinged to each other and the sliding seat, the clamping jaws can be driven to synchronously clamp the sample test tubes when the square rod moves rightwards by matching with the elastic pulling of a spring, the operation steps are reduced, the working efficiency is improved, the sample test tubes can be driven to tilt and deflect by the rotation of a gear I, the sample taking convenience is improved, and meanwhile, a cap can be automatically broken off by matching with a limit groove arranged on a limit rod, so that the using convenience of the device is further improved.
Description
Technical Field
The invention relates to the field of nucleic acid sample extraction, in particular to a novel coronal nucleic acid sample semiautomatic extraction device.
Background
The novel coronavirus is a coronavirus with high infectivity and high concealment, and since the occurrence of the coronavirus, the coronavirus has extremely great loss for human society, and the prevention and the control of the coronavirus by adopting a scientific and reasonable method are very necessary to reduce the damage of new coronavirus epidemic situation to human society as much as possible at present.
In epidemic prevention and control process, in order to timely distinguish infected people at the positions, a large number of nucleic acid samples need to be extracted and analyzed for the closely contacted people, when extraction work is carried out, a large number of new crown nucleic acid samples placed on a test tube rack are faced, workers need to take test tubes one by one, extraction work is carried out, single-cycle taking operation leads to high labor intensity of the workers, the efficiency of extracting the new crown nucleic acid samples cannot be improved, and confusion and cross infection are easily caused by manual taking.
Therefore, we propose a novel coronal nucleic acid sample semiautomatic extraction device to solve some of the problems in the prior art.
Disclosure of Invention
1. Technical problem to be solved
Aiming at the problems existing in the prior art, the invention aims to provide a novel crown nucleic acid sample semiautomatic extraction device, which can realize semiautomatic extraction of a novel crown nucleic acid sample, the transverse square rod is connected inside a sliding seat in a sliding manner, the sliding seat is sleeved outside a vertical frame in a sliding manner, a plurality of sample test tubes which are sequentially inserted on a test tube rack can be extracted one by matching with the conveying of a conveying assembly, the manual taking of a worker is not needed, the right end of a guy rope is fixedly connected with the left ends of two clamping jaws which are mutually hinged, the left ends of the guy rope are fixedly connected to the outer end wall of the sliding seat, the clamping jaws can be driven to clamp the sample test tubes synchronously when the square rod moves rightwards by matching with the elasticity of a spring, the operation steps are reduced, the working efficiency of the device is convenient to be improved, the sample test tubes can be driven to deflect obliquely by the rotation of a gear one, the convenience of sample taking is facilitated to be improved, and meanwhile, the cap can be opened automatically by matching with a limit groove which is arranged on a limit rod.
2. Technical proposal
In order to solve the problems, the invention adopts the following technical scheme.
The utility model provides a semi-automatic extraction element of new crown nucleic acid sample, including conveying assembly, the test-tube rack is installed to conveying assembly's top, and the through-hole has evenly been seted up at the top of test-tube rack, the inside of every through-hole all vertically inserts and is equipped with the sample test tube, and the upper end opening part cover of sample test tube is equipped with the block, conveying assembly's left side intermediate position department fixed mounting has the master control box, and the top fixed mounting of master control box has the vertical frame, the outside sliding connection of vertical frame has the sliding seat, the top intermediate position department fixed mounting of master control box has the electric telescopic handle of vertical setting, and the flexible end and the bottom fixed connection of sliding seat of electric telescopic handle;
the inside transverse sliding connection of sliding seat has the square pole, and the right-hand member of square pole rotates and is connected with gear one, fixedly connected with mount pad on the outer end wall in the right side of gear one, and the inside right side of mount pad installs two clamping jaws for "X" alternately articulated, the inside activity of square pole is run through there is the cable, and the right-hand member of cable respectively with the left end fixed connection of two clamping jaws, the left end fixed connection of cable is on the outer end wall of sliding seat, all fixed mounting has a plurality of springs between the inner end wall of the left end of every clamping jaw and mount pad, a plurality of springs through corresponding setting up respectively and the mount pad constitution elastic swivelling joint of two clamping jaws, the top fixed mounting of square pole has the rack bar one of transverse arrangement, the top fixed mounting of sliding seat has servo motor two, and fixed mounting has the drive wheel one with rack bar one engaged with in the drive shaft of servo motor two, the top fixed mounting of vertical frame has the switch.
Further, the conveying assembly comprises a base placed on the tabletop, the front end and the rear end of the base are internally and rotatably connected with symmetrically arranged conveying rollers, the outer sides of the two conveying rollers are movably sleeved with a conveying belt, a first servo motor is fixedly installed on the outer end wall of the conveying assembly, a driving shaft of the first servo motor is fixedly connected with one of the conveying rollers, and the test tube rack is placed on one side of the front face of the top of the conveying belt.
Further, the sponge cushion arranged right below the through hole is fixedly arranged on the inner end wall of the bottom of the test tube rack, the magnets are fixedly arranged at four corners of the bottom of the test tube rack, and a plurality of small iron sheets are uniformly fixed in the conveying belt.
Further, the left end of the square rod is internally and rotatably connected with a guide wheel, and the inhaul cable is movably sleeved on the outer side of the guide wheel.
Further, rubber pads are fixedly installed on the outer end wall of one side, close to each other, of the two clamping jaws, a plurality of anti-slip stripes are uniformly assembled on the outer surface of each rubber pad, and a pressure sensor is fixedly installed inside each rubber pad.
Further, a second rack rod which is vertically arranged is fixedly arranged on the outer end wall of the upper part of the vertical frame, the bottom of the sliding seat is rotationally connected with a sleeve rod, a second driving wheel which is matched with the second rack rod is fixedly sleeved on the outer side of the sleeve rod, a spline rod which is transversely arranged is arranged in the sleeve rod, the left end and the right end of the spline rod are rotationally connected to the bottom of the square rod, and a second gear which is meshed with the first gear is fixedly arranged at the right end of the spline rod.
Further, the inside of the loop bar is provided with a spline hole which is matched with the outer side of the spline bar in size, and the loop bar is in sliding connection with the spline bar.
Further, the cap is movably connected above the sample tube through an elastic plastic sheet, and a clamping block is fixedly arranged on the outer end wall of the front surface of the cap.
Further, the right end front surface of the square rod is fixedly provided with a limiting rod which is arranged corresponding to the clamping block, and a limiting groove which is matched with the limiting rod is formed in the outer end wall of one side, close to the clamping block, of the limiting rod, and the opening at the right end of the limiting groove gradually expands outwards from left to right.
Further, the outer end walls of the upper side and the lower side of the vertical frame are also provided with pressure sensors.
3. Advantageous effects
Compared with the prior art, the invention has the advantages that:
(1) This scheme is through the inside at the sliding seat with the square pole sliding connection who transversely sets up to establish the vertical frame outside at vertical setting with the sliding seat sliding sleeve, cooperation conveying assembly's transport, can insert a plurality of sample test tubes that establish in proper order on the test-tube rack and draw the operation one by one, need not the staff and take, be convenient for ensure the orderly nature that the nucleic acid sample detected, and be favorable to reducing staff's work burden, through the left end fixed connection with two articulated clamping jaw each other with the right-hand member of cable, and with the left end fixed connection of cable on the outer end wall of sliding seat, the elasticity of cooperation spring is pulled, can drive the clamping jaw and carry out synchronous clamp to sample test tube when the square pole moves right and press from both sides tight operation, the effectual centre gripping lifting efficiency that has promoted the device.
(2) Through placing the test-tube rack that is equipped with sample test tube at the top of conveyer belt, with the help of the intermittent type start of servo motor one, can carry out intermittent type removal to a plurality of sample test tubes, be convenient for draw a plurality of sample test tubes in proper order, simultaneously, it is convenient that the test-tube rack that directly places at the conveyer belt top is changed, is favorable to promoting the efficiency of sample extraction work.
(3) Through the below with foam-rubber cushion fixed mounting at the through-hole, can protect the sample tube bottom of inserting in the through-hole, avoid sample tube bottom and test-tube rack collision to lead to breaking, the effectual safety in utilization that promotes the device, through the inside with a plurality of little iron sheet even fixed mounting at the conveyer belt, and with magnet fixed mounting in test-tube rack bottom four corners department, with the help of the magnetic adsorption between magnet and the little iron sheet, can fix a position the placement position of test-tube rack, be favorable to promoting the device and snatch the accuracy that promotes to sample tube, simultaneously, the stability on the conveyer belt is placed to the test-tube rack of also being convenient for.
(4) Through rotating the guide wheel and connecting the left end at the square pole, can carry out effective guide to the removal of cable, avoid friction between cable and the square pole, effectually reduced the cracked probability of cable wearing and tearing, be convenient for promote the device's job stabilization nature.
(5) Through installing the rubber pad on the outer end wall of one side that two clamping jaws press close to each other, can effectively promote the clamping jaw to the frictional force when sample tube outer end wall centre gripping snatched, promoted its stability when snatching and promoting, simultaneously, through the protection of rubber pad, can effectually avoid sample tube to receive the extrusion and break.
(6) Through installing pressure sensor in the inside of rubber pad, can detect the clamping state of clamping jaw, simultaneously, through installing pressure sensor on the upper and lower side outer end wall of erectting the frame, signal that produces when touching through sliding seat and pressure sensor can fix a position the sliding seat and be in the position of upper and lower end for the device can stop and start through the nimble control of switch, the effectual nimble stability when having ensured the device use.
(7) Through with rack bar two fixed mounting on the top outer end wall of sliding seat to will rotate the bottom of connecting at the sliding seat with the drive wheel of rack bar two looks adaptation, can provide rotary drive to gear one at the in-process that the sliding seat removed the upper end, change the inclination of mount pad, thereby realize that sample tube is snatched and promoted the back automatic skew, effectually promoted the staff and taken the convenience of taking the sample nucleic acid sample in this test tube, through inserting the spline bar slip in the splined hole of seting up inside the loop bar, make the loop bar can slide about the outside of spline bar, effectually ensured the stability of power switching between loop bar and the spline bar in the square bar removal process.
(8) The cap is opened through breaking the top of cover cap swing joint at sample test tube through elastic plastic piece, simultaneously, effectually avoid the cover cap to drop and lose, through with fixture block fixed mounting on the front outer end wall of cover cap, provide the point of application for breaking the cover cap off with the fingers and thumb, the effectual use convenience that has promoted the device, through with gag lever post fixed mounting at the right-hand member of square pole, and will offer the inside at the gag lever post with the spacing groove of fixture block looks adaptation, can form the restriction to the fixture block through the spacing groove, the rotation of cooperation mount pad, carry out automatic breaking off and automatic lock operation to the cover cap off with the fingers and thumb, need not the manual operation to the cover cap of staff, the sample has been improved and has been extracted the convenience, and be favorable to reducing the probability that cross infection appears in the sample extraction.
Drawings
FIG. 1 is a perspective view of the present invention;
FIG. 2 is a top view of the present invention;
FIG. 3 is a schematic view of the structure of the present invention in the extracted state;
FIG. 4 is a schematic view of the structure of the rack and sample tube of the present invention;
FIG. 5 is a schematic view of the structure of a sample tube of the present invention;
FIG. 6 is a schematic view of the structure of the jaw of the present invention in an initial state;
FIG. 7 is a top partial cross-sectional view of FIG. 6;
FIG. 8 is a rear cross-sectional view of FIG. 6;
FIG. 9 is a schematic view of the clamping jaw of the present invention in a clamped state;
FIG. 10 is a schematic view of the structure of the jaw of the present invention in an inclined state;
fig. 11 is a side view of fig. 10.
The reference numerals in the figures illustrate:
1. a transport assembly; 101. a base; 102. a conveying roller; 103. a conveyor belt; 104. a servo motor I; 2. a test tube rack; 201. a sponge cushion; 202. a magnet; 3. a sample tube; 301. capping; 302. a clamping block; 4. a master control box; 401. a vertical frame; 402. a sliding seat; 403. an electric telescopic rod; 5. square rods; 501. a first gear; 502. a mounting base; 503. a clamping jaw; 504. a guy cable; 505. a spring; 506. a rack bar I; 507. a servo motor II; 508. a first driving wheel; 6. a rack bar II; 601. a loop bar; 602. a second driving wheel; 603. a spline bar; 604. a second gear; 7. a limit rod; 701. a limit groove; 8. and (3) a switch.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention; it is apparent that the described embodiments are only some embodiments of the present invention, not all embodiments, and that all other embodiments obtained by persons of ordinary skill in the art without making creative efforts based on the embodiments in the present invention are within the protection scope of the present invention.
In the description of the present invention, it should be noted that the positional or positional relationship indicated by the terms such as "upper", "lower", "inner", "outer", "top/bottom", etc. are based on the positional or positional relationship shown in the drawings, are merely for convenience of describing the present invention and simplifying the description, and do not indicate or imply that the apparatus or elements referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "configured to," "engaged with," "connected to," and the like are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present invention will be understood in specific cases by those of ordinary skill in the art.
Example 1:
referring to fig. 1-3, a novel crown nucleic acid sample semiautomatic extracting device comprises a conveying assembly 1, wherein the conveying assembly 1 comprises a base 101 placed on a tabletop, conveying rollers 102 which are symmetrically arranged are rotatably connected inside front and rear ends of the base 101, a conveying belt 103 is movably sleeved on the outer sides of the two conveying rollers 102, a first servo motor 104 is fixedly installed on the outer end wall of the conveying assembly 1, a driving shaft of the first servo motor 104 is fixedly connected with one of the conveying rollers 102, a test tube rack 2 is placed on one side of the front surface of the top of the conveying belt 103, and when the device works, the first servo motor 104 is electrified to start to drive the conveying rollers 102 fixedly connected to the driving shaft to rotate, the conveying belt 103 sleeved on the outer side of the first servo motor 104 is driven to rotate through the rotation of the conveying rollers 102, so that intermittent conveying is performed on the test tube racks 2 placed on the conveying belt 103, and the stable and orderly samples are ensured one by one.
Referring to fig. 4-5, a test tube rack 2 is installed above the conveying assembly 1, through holes are uniformly formed in the top of the test tube rack 2, sample test tubes 3 are vertically inserted into the inside of each through hole, a cap 301 is sleeved at the opening of the upper end of each sample test tube 3, the cap 301 is movably connected above the sample test tubes 3 through an elastic plastic sheet, a clamping block 302 is fixedly installed on the outer end wall of the front face of the cap 301, and when the device works, the cap 301 is movably connected above the sample test tubes 3 through the elastic plastic sheet, the cap 301 can be opened through snapping, meanwhile, the cap 301 is effectively prevented from falling off and losing, and a force application point is provided for snapping the cap 301 through fixedly installing the clamping block 302 on the outer end wall of the front face of the cap 301, so that the use convenience of the device is effectively improved.
Referring to fig. 4, the sponge pad 201 is fixedly installed on the inner end wall of the bottom of the test tube rack 2 and is arranged under the through hole, the magnets 202 are fixedly installed at four corners of the bottom of the test tube rack 2, a plurality of small iron sheets are uniformly fixed inside the conveying belt 103, the device is convenient to replace by placing the test tube rack 2 above the conveying belt 103, the test tube rack 2 is convenient to continuously and effectively extract a plurality of sample test tubes 3 on the test tube rack 2, meanwhile, the sponge pad 201 is fixedly installed below the through hole, the bottom of the sample test tube 3 inserted in the through hole can be protected, the bottom of the sample test tube 3 is prevented from being broken due to collision with the test tube rack 2, the use safety of the device is effectively improved, the magnet 202 is fixedly installed inside the conveying belt 103 by means of the plurality of small iron sheets, and the magnet 202 is positioned at four corners between the bottom of the test tube rack 2 by means of magnetic adsorption between the magnets 202 and the small iron sheets, the placing position of the test tube rack 2 is favorable for lifting the device to accurately guarantee the sample test tube rack 3, and meanwhile, the test tube rack 2 is convenient to place on the conveying belt 2 is stable.
Referring to fig. 1, a main control box 4 is fixedly installed at a middle position of the left side of the conveying assembly 1, a vertical frame 401 is fixedly installed at the top of the main control box 4, a sliding seat 402 is slidably connected to the outer side of the vertical frame 401, an electric telescopic rod 403 is fixedly installed at a middle position of the top of the main control box 4, and a telescopic end of the electric telescopic rod 403 is fixedly connected with the bottom of the sliding seat 402.
Referring to fig. 6-8, the inside of the sliding seat 402 is transversely slidingly connected with the square rod 5, the right end of the square rod 5 is rotationally connected with the gear one 501, the right outer end wall of the gear one 501 is fixedly connected with the mounting seat 502, two clamping jaws 503 which are in 'X' -shaped cross hinge are mounted on the right side of the inside of the mounting seat 502, rubber pads are fixedly mounted on the outer end wall of one side of the two clamping jaws 503, a plurality of anti-slip stripes are uniformly mounted on the outer surface of the rubber pads, a pressure sensor is fixedly mounted inside the rubber pads, and during operation of the device, the friction force of the clamping jaws 503 on the outer end wall of the sample test tube 3 during clamping and grabbing is effectively improved, stability during grabbing and lifting of the sample test tube is improved, meanwhile, the sample test tube 3 is effectively prevented from being broken through protection of the rubber pads, and signals are transmitted to the processor inside the main control box 4 by the pressure sensor mounted inside the rubber pads when the clamping the sample test tube 3, and the servo motor 104 is in a standby state, and the servo device is effectively prevented from being started.
Referring to fig. 7, a pull rope 504 is movably penetrated through the square rod 5, the right end of the pull rope 504 is fixedly connected with the left ends of two clamping jaws 503 respectively, the left end of the pull rope 504 is fixedly connected to the outer end wall of the sliding seat 402, a plurality of springs 505 are fixedly installed between the left end of each clamping jaw 503 and the inner end wall of the installation seat 502, the two clamping jaws 503 are respectively in elastic rotary connection with the installation seat 502 through a plurality of springs 505 which are correspondingly arranged, a guide wheel is rotatably connected to the inside of the left end of the square rod 5, and the pull rope 504 is movably sleeved on the outer side of the guide wheel.
Referring to fig. 1 and 6-7, a rack bar 506 is fixedly arranged at the top of the square bar 5, a servo motor two 507 is fixedly arranged at the top of the sliding seat 402, a driving wheel one 508 meshed with the rack bar 506 is fixedly arranged on a driving shaft of the servo motor two 507, a switch 8 is fixedly arranged at the top of the vertical frame 401, and pressure sensors are also arranged on the outer end walls of the upper side and the lower side of the vertical frame 401.
Referring to fig. 6 and 8-11, a rack bar two 6 is fixedly installed on the upper outer end wall of the vertical frame 401, a sleeve rod 601 is rotatably connected to the bottom of the sliding seat 402, a driving wheel two 602 matched with the rack bar two 6 is fixedly sleeved on the outer side of the sleeve rod 601, a spline rod 603 is transversely installed in the sleeve rod 601, the left end and the right end of the spline rod 603 are rotatably connected to the bottom of the square rod 5, a gear two 604 meshed with the gear two 501 is fixedly installed at the right end of the spline rod 603, and when the device works, when the sliding seat 402 moves upwards under the support of the electric telescopic rod 403, a driving wheel two 602 installed at the bottom of the sliding seat 402 is meshed with the rack bar two 6, so that the sliding seat 402 drives the sleeve rod 601 to rotate, the spline rod 603 internally installed in the sleeve rod 601 is driven to rotate, the gear two 604 fixed at the right end of the spline rod 603 is driven to rotate, the mounting seat 502 is driven to rotate, a sample 3 clamped between the two clamping jaws 503 is deflected, and the sample 3 lifted to the sample 3 is conveniently placed in the sample tube 3 by a sample holding person.
When the sliding seat 402 moves downwards to reset, under the relative action, the clamping jaw 503 drives the sample test tube 3 to reversely deflect and reset to a vertical state, so that the sample test tube 3 after the end of extraction is inserted into a corresponding through hole on the test tube rack 2 again, the clamping jaw 503 is also convenient for continuously clamping and deflecting the next group of sample test tubes 3, the second rack rod 6 is fixedly arranged on the outer end wall above the sliding seat 402, the second driving wheel 602 matched with the second rack rod 6 is rotationally connected to the bottom of the sliding seat 402, the first gear 501 can be driven in rotation in the process of moving the sliding seat 402 to the upper end, the inclination angle of the mounting seat 502 is changed, and therefore, the automatic deflection of the sample test tubes 3 after the sample test tubes 3 are grabbed and lifted is realized, and the convenience of taking the nucleic acid samples in the sample test tubes 3 by staff is effectively improved.
Referring to fig. 6 and fig. 9-10, a splined hole matched with the outer side of the spline rod 603 is formed in the sleeve rod 601, the sleeve rod 601 is slidably connected with the spline rod 603, and when the device works, the spline rod 603 matched with the splined hole is inserted into the sleeve rod 601 through the splined hole, so that the sleeve rod 601 can slide left and right on the outer side of the spline rod 603, and meanwhile the spline rod 603 can be driven to synchronously rotate when the sleeve rod 601 rotates, so that the stability of power switching between the sleeve rod 601 and the spline rod 603 in the moving process of the square rod 5 is effectively guaranteed.
Referring to fig. 10-11, the right end face of the square rod 5 is fixedly provided with a limit rod 7 corresponding to the clamping block 302, and the limit rod 7 is close to an outer end wall of one side of the clamping block 302 and is provided with a limit groove 701 matched with the limit rod, the right end opening of the limit groove 701 gradually expands outwards from left to right, when the device works, the square rod 5 is driven to move rightwards in the process of moving the limit rod 7 synchronously to move rightwards, the limit groove 701 formed in the limit rod 7 is clamped at the outer side of the clamping block 302, when the clamping jaw 503 drives the sample test tube 3 to deflect, the limit rod 7 keeps still, under the relative action, the cap 301 sleeved at the upper end of the sample test tube 3 is broken by the limit rod 7, so that the sample test tube 3 is automatically opened without the need of manually breaking the cap 301 by a worker, the convenience of taking a nucleic acid sample is effectively improved, meanwhile, the probability of cross infection of the sample is reduced to a certain extent, when the clamping jaw 503 drives the sample test tube 3 to reversely deflect and reset, under the relative action, the limit of the limit groove 701 in the limit groove in the limit rod 7 is limited, so that the top of the cap 301 is buckled at the top of the sample test tube 3 again, and the sample test tube 3 is closed after the sample test tube 3 is opened, and the sample test tube 3 is opened.
Referring to fig. 1-11, when the device works, a worker starts the device by pressing a switch 8 fixed at the top of a vertical frame 401, a lower conveying component 1 starts to drive a test tube rack 2 placed above the lower conveying component to intermittently move, a plurality of sample test tubes 3 inserted in the test tube rack 2 are conveyed one by one, a sliding seat 402 is positioned at the lowest end position in an initial state, a servo motor two 507 installed at the top of the sliding seat 402 is electrified and started to drive a driving wheel one 508 fixed on the driving shaft of the servo motor two 508 to rotate, a square rod 5 is moved rightwards by tooth meshing between the driving wheel one 508 and a rack rod one 506, when the square rod 5 moves rightwards, as the left end of the sliding seat 504 is fixedly connected with the left end wall of the sliding seat 402, the left outer end wall of the sliding seat 402 is close to the left end of the square rod 5, the sliding seat 504 is loosened for pulling two clamping jaws 503 on the right side, under elastic rebound of a plurality of springs 505 correspondingly arranged, the two symmetrically arranged clamping jaws 503 rotate relatively, the sample test tubes 3 positioned on the right side are clamped 3, the symmetrically arranged clamping jaws 3 are clamped by the clamping jaws 3, the sample clamping jaws are clamped by the symmetrically arranged at the two clamping jaws 3, the clamping jaws are arranged at the bottom of the clamping jaws 3, the sample clamping jaws are stretched upwards, and the sample tubes are stretched upwards, and the sample samples are respectively, and the sample are extracted, and the sample are stretched.
After the extraction is finished, the electric telescopic rod 403 drives the sliding seat 402 to move downwards for resetting, the square rod 5 returns to the initial position, the conveying component 1 drives the test tube rack 2 to move again, a plurality of sample test tubes 3 placed on the test tube rack 2 continuously circulate are sequentially extracted one by one, the right end of the inhaul cable 504 is fixedly connected with the left ends of the two clamping jaws 503 hinged with each other, the left ends of the inhaul cable 504 are fixedly connected to the outer end wall of the sliding seat 402, the elastic pulling of the square rod 5 is matched, the two clamping jaws 503 mounted on the right side of the square rod can be driven to rotate relatively for clamping when the square rod 5 moves rightwards, synchronous clamping operation is carried out while moving, the operation steps are effectively reduced, the convenience in use of the device is improved, the square rod 5 is slidingly connected to the inside of the sliding seat 402, the sliding seat 402 is sleeved outside the vertical frame 401 which is vertically arranged, the plurality of sample test tubes 3 which are sequentially inserted on the test tube rack 2 can be sequentially extracted one by matching with the conveying of the conveying component 1, manual taking of workers is not needed, the workers can conveniently carry out the manual taking of nucleic acid samples, the orderly and the nucleic acid samples can be conveniently and the load of workers can be conveniently reduced.
The above is only a preferred embodiment of the present invention; the scope of the invention is not limited in this respect. Any person skilled in the art, within the technical scope of the present disclosure, may apply to the present invention, and the technical solution and the improvement thereof are all covered by the protection scope of the present invention.
Claims (4)
1. A novel coronal nucleic acid sample semi-automatic extraction device is characterized in that: the automatic feeding device comprises a conveying assembly (1), wherein the conveying assembly (1) comprises a base (101) placed on a tabletop, conveying rollers (102) which are symmetrically arranged are rotationally connected inside the front end and the rear end of the base (101), conveying belts (103) are movably sleeved on the outer sides of the two conveying rollers (102), a first servo motor (104) is fixedly arranged on the outer end wall of the conveying assembly (1), and a driving shaft of the first servo motor (104) is fixedly connected with one of the conveying rollers (102); the test tube rack (2) is arranged above the conveying assembly (1), the test tube rack (2) is placed on one side of the front of the top of the conveying belt (103), through holes are uniformly formed in the top of the test tube rack (2), sample test tubes (3) are vertically inserted into the through holes, and caps (301) are sleeved at openings at the upper ends of the sample test tubes (3); a main control box (4) is fixedly arranged at the middle position of the left side of the conveying assembly (1), a vertical frame (401) is fixedly arranged at the top of the main control box (4), a sliding seat (402) is connected to the outer side of the vertical frame (401) in a sliding manner, an electric telescopic rod (403) which is vertically arranged is fixedly arranged at the middle position of the top of the main control box (4), and the telescopic end of the electric telescopic rod (403) is fixedly connected with the bottom of the sliding seat (402); the inside of the sliding seat (402) is transversely connected with a square rod (5) in a sliding manner, the right end of the square rod (5) is rotationally connected with a first gear (501), the right outer end wall of the first gear (501) is fixedly connected with a mounting seat (502), and two clamping jaws (503) which are in X-shaped cross hinge connection are arranged on the right side of the inside of the mounting seat (502); a pull rope (504) is movably penetrated in the square rod (5), the right ends of the pull ropes (504) are fixedly connected with the left ends of the two clamping jaws (503) respectively, the left ends of the pull ropes (504) are fixedly connected to the outer end wall of the sliding seat (402), a plurality of springs (505) are fixedly arranged between the left end of each clamping jaw (503) and the inner end wall of the mounting seat (502), and the two clamping jaws (503) are in elastic rotary connection with the mounting seat (502) through the plurality of springs (505) which are correspondingly arranged; a guide wheel is rotatably connected inside the left end of the square rod (5), and the inhaul cable (504) is movably sleeved on the outer side of the guide wheel; a first rack bar (506) which is transversely arranged is fixedly arranged at the top of the square bar (5), a second servo motor (507) is fixedly arranged at the top of the sliding seat (402), a first driving wheel (508) which is meshed with the first rack bar (506) is fixedly arranged on a driving shaft of the second servo motor (507), and a switch (8) is fixedly arranged at the top of the vertical frame (401); a second rack rod (6) which is vertically arranged is fixedly arranged on the outer end wall above the vertical frame (401), a sleeve rod (601) is rotationally connected to the bottom of the sliding seat (402), a second driving wheel (602) which is matched with the second rack rod (6) is fixedly sleeved on the outer side of the sleeve rod (601), a spline rod (603) which is transversely arranged is arranged in the sleeve rod (601), the left end and the right end of the spline rod (603) are rotationally connected to the bottom of the square rod (5), and a second gear (604) which is meshed with the first gear (501) is fixedly arranged at the right end of the spline rod (603); a spline hole matched with the outer side of the spline rod (603) in size is formed in the sleeve rod (601), and the sleeve rod (601) is connected with the spline rod (603) in a sliding mode; the cap (301) is movably connected above the sample test tube (3) through an elastic plastic sheet, a clamping block (302) is fixedly arranged on the outer end wall of the front surface of the cap (301), a limiting rod (7) which is arranged corresponding to the clamping block (302) is fixedly arranged on the front surface of the right end of the square rod (5), a limiting groove (701) which is matched with the limiting rod (7) is formed in the outer end wall of one side, close to the clamping block (302), of the limiting rod, and the opening of the right end of the limiting groove (701) gradually expands outwards from left to right; the device can extract the operation one by one to a plurality of sample test tubes (3) that insert in proper order on test-tube rack (2), drive when square pole (5) are moved rightwards clamping jaw (503) is right sample test tube (3) is pressed from both sides simultaneously, change when sliding seat (402) are upwards moved inclination of mount pad (502) is in order to right sample test tube (3) is synchronous skew, is right simultaneously the cap (301) is broken off with fingers and thumb automatically.
2. The semiautomatic extraction device for a novel coronal nucleic acid sample according to claim 1, wherein: the novel test tube rack is characterized in that a sponge pad (201) arranged right below the through hole is fixedly arranged on the inner end wall of the bottom of the test tube rack (2), magnets (202) are fixedly arranged at four corners of the bottom of the test tube rack (2), and a plurality of small iron sheets are uniformly fixed in the conveying belt (103).
3. The semiautomatic extraction device for a novel coronal nucleic acid sample according to claim 1, wherein: two clamping jaws (503) are all fixed mounting has the rubber pad on the outer end wall of one side that is pressed close to each other, and evenly be equipped with a plurality of anti-skidding stripes on the surface of rubber pad, the inside fixed mounting of rubber pad has pressure sensor.
4. The semiautomatic extraction device for a novel coronal nucleic acid sample according to claim 1, wherein: pressure sensors are arranged on the outer end walls of the upper side and the lower side of the vertical frame (401).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202111429024.5A CN114015557B (en) | 2021-11-29 | 2021-11-29 | Semi-automatic extraction device for novel coronal nucleic acid sample |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202111429024.5A CN114015557B (en) | 2021-11-29 | 2021-11-29 | Semi-automatic extraction device for novel coronal nucleic acid sample |
Publications (2)
Publication Number | Publication Date |
---|---|
CN114015557A CN114015557A (en) | 2022-02-08 |
CN114015557B true CN114015557B (en) | 2023-11-14 |
Family
ID=80066854
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202111429024.5A Active CN114015557B (en) | 2021-11-29 | 2021-11-29 | Semi-automatic extraction device for novel coronal nucleic acid sample |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN114015557B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114522749B (en) * | 2022-04-02 | 2023-09-01 | 福建博奥医学检验所有限公司 | Automatic change new coronavirus nucleic acid sampling and detecting test tube collection device |
Citations (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN206706091U (en) * | 2017-03-31 | 2017-12-05 | 深圳市汇研科创生物科技有限公司 | A kind of nucleic acid cuvette construction |
CN108467830A (en) * | 2013-03-14 | 2018-08-31 | 简·探针公司 | Diagnostic system and method |
WO2020027566A1 (en) * | 2018-08-01 | 2020-02-06 | 주식회사 미코바이오메드 | Nucleic acid extraction device and operating method therefor |
CN210656892U (en) * | 2019-08-23 | 2020-06-02 | 臻悦生物科技江苏有限公司 | Nucleic acid extraction kit for preventing cross contamination |
CN211013682U (en) * | 2019-11-29 | 2020-07-14 | 青岛市市立医院 | Urine test tube circulation sampling device for medical clinical laboratory |
CN211057123U (en) * | 2019-10-23 | 2020-07-21 | 成都瀚辰光翼科技有限责任公司 | Full-automatic nucleic acid extraction and real-time fluorescence quantitative PCR integrated device |
CN112089447A (en) * | 2020-10-21 | 2020-12-18 | 高进贤 | High-efficiency automatic intelligent acquisition system for new coronavirus nucleic acid |
CN112090467A (en) * | 2020-10-21 | 2020-12-18 | 高进贤 | Automatic change new coronavirus nucleic acid sampling detection test tube collection device |
CN113046224A (en) * | 2021-03-17 | 2021-06-29 | 杭州博日科技股份有限公司 | Full-automatic gene analysis apparatus and gene analysis method |
CN113304796A (en) * | 2021-02-18 | 2021-08-27 | 华中科技大学同济医学院附属协和医院 | Automatic change new coronavirus nucleic acid sampling detection test tube collection device |
CN214457870U (en) * | 2020-09-10 | 2021-10-22 | 襄阳市远杰精密机械有限公司 | Portable full-automatic nucleic acid extraction appearance |
CN214881514U (en) * | 2021-05-19 | 2021-11-26 | 台州市中心医院(台州学院附属医院) | Full-automatic nucleic acid detection assembly line |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4210306B2 (en) * | 2007-01-15 | 2009-01-14 | 株式会社アイディエス | Test tube automatic opening device |
-
2021
- 2021-11-29 CN CN202111429024.5A patent/CN114015557B/en active Active
Patent Citations (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108467830A (en) * | 2013-03-14 | 2018-08-31 | 简·探针公司 | Diagnostic system and method |
CN206706091U (en) * | 2017-03-31 | 2017-12-05 | 深圳市汇研科创生物科技有限公司 | A kind of nucleic acid cuvette construction |
WO2020027566A1 (en) * | 2018-08-01 | 2020-02-06 | 주식회사 미코바이오메드 | Nucleic acid extraction device and operating method therefor |
CN210656892U (en) * | 2019-08-23 | 2020-06-02 | 臻悦生物科技江苏有限公司 | Nucleic acid extraction kit for preventing cross contamination |
CN211057123U (en) * | 2019-10-23 | 2020-07-21 | 成都瀚辰光翼科技有限责任公司 | Full-automatic nucleic acid extraction and real-time fluorescence quantitative PCR integrated device |
CN211013682U (en) * | 2019-11-29 | 2020-07-14 | 青岛市市立医院 | Urine test tube circulation sampling device for medical clinical laboratory |
CN214457870U (en) * | 2020-09-10 | 2021-10-22 | 襄阳市远杰精密机械有限公司 | Portable full-automatic nucleic acid extraction appearance |
CN112089447A (en) * | 2020-10-21 | 2020-12-18 | 高进贤 | High-efficiency automatic intelligent acquisition system for new coronavirus nucleic acid |
CN112090467A (en) * | 2020-10-21 | 2020-12-18 | 高进贤 | Automatic change new coronavirus nucleic acid sampling detection test tube collection device |
CN113304796A (en) * | 2021-02-18 | 2021-08-27 | 华中科技大学同济医学院附属协和医院 | Automatic change new coronavirus nucleic acid sampling detection test tube collection device |
CN113046224A (en) * | 2021-03-17 | 2021-06-29 | 杭州博日科技股份有限公司 | Full-automatic gene analysis apparatus and gene analysis method |
CN214881514U (en) * | 2021-05-19 | 2021-11-26 | 台州市中心医院(台州学院附属医院) | Full-automatic nucleic acid detection assembly line |
Also Published As
Publication number | Publication date |
---|---|
CN114015557A (en) | 2022-02-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN114015557B (en) | Semi-automatic extraction device for novel coronal nucleic acid sample | |
CN109577657B (en) | Brick conveying frame for wall building | |
CN107752938A (en) | A kind of cup cleaning equipment | |
CN212311782U (en) | Clamp for glass production | |
JP2756558B2 (en) | Towel cloth cutting equipment | |
CN209904184U (en) | Tear type paper equipment that leaves | |
CN114541718A (en) | Building construction platform with safeguard function | |
CN104723653A (en) | Mobile phone protection film tearing mechanism | |
CN211418458U (en) | Hand-held type air entrainment brick handling tool | |
CN213828978U (en) | Quick recoverer for aluminum die pins | |
CN212807883U (en) | PE material feed pipe intensity detection device | |
CN211793577U (en) | Mouse experiment live object arrest auxiliary device | |
CN218601031U (en) | Data line epidermis intensity detector | |
CN209864342U (en) | Critical patient's multi-purpose vice stretcher auxiliary device of non-woven fabrics | |
CN210388175U (en) | Magnetic attraction piece transfer device | |
CN212648761U (en) | Electrical equipment dustproof protection device | |
CN209257568U (en) | A kind of handbag threading machine perforating device | |
CN219905621U (en) | Easy-to-use transfer robot | |
CN111806894A (en) | Automatic ware of delivering of tweezers for internal medicine | |
CN209777634U (en) | Brick clamping device | |
CN217880982U (en) | Frame-type strander for cable production | |
CN216164959U (en) | Vacuum sterilization equipment for pet food processing | |
CN109353075A (en) | A kind of handbag threading machine perforating device | |
CN211797016U (en) | Portable experimental animal grabbing and injecting device | |
CN216870243U (en) | Toughened glass strength detection device |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant |