CN114009353A - Experimental device for be used for shining laboratory mouse - Google Patents

Experimental device for be used for shining laboratory mouse Download PDF

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Publication number
CN114009353A
CN114009353A CN202111416324.XA CN202111416324A CN114009353A CN 114009353 A CN114009353 A CN 114009353A CN 202111416324 A CN202111416324 A CN 202111416324A CN 114009353 A CN114009353 A CN 114009353A
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CN
China
Prior art keywords
shell
box body
experimental
laboratory
lamp
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Pending
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CN202111416324.XA
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Chinese (zh)
Inventor
常好才
欧阳雯雯
李俊宇
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South China Normal University
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South China Normal University
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Priority to CN202111416324.XA priority Critical patent/CN114009353A/en
Publication of CN114009353A publication Critical patent/CN114009353A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K1/00Housing animals; Equipment therefor
    • A01K1/02Pigsties; Dog-kennels; Rabbit-hutches or the like
    • A01K1/03Housing for domestic or laboratory animals
    • A01K1/031Cages for laboratory animals; Cages for measuring metabolism of animals
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K1/00Housing animals; Equipment therefor
    • A01K1/02Pigsties; Dog-kennels; Rabbit-hutches or the like
    • A01K1/035Devices for use in keeping domestic animals, e.g. fittings in housings or dog beds

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  • Life Sciences & Earth Sciences (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

The invention discloses an experimental device for irradiating a laboratory mouse, which comprises a shell, a supporting plate and a box body for placing the laboratory mouse, wherein the shell is fixedly connected with the supporting plate, the inner wall of the shell is provided with a guide groove, the outer wall of the box body is provided with a bulge matched with the guide groove, the box body is positioned in the shell and is in sliding connection with the shell, the outer wall of the shell is provided with an irradiation lamp, the shell is provided with an adjusting mechanism for adjusting the irradiation lamp, the adjusting mechanism comprises an adjusting rod, a spherical part and a lamp holder, the adjusting rod is connected with the upper end of the spherical part, the spherical part is connected with the shell, the lower end of the spherical part is connected with the lamp holder, and the lamp holder is connected with the irradiation lamp; adopt the adjustment mechanism of adjustable lamp angle, make the irradiation efficiency of laboratory mouse improve, adjust the irradiation area, convenient operation, accommodation is wide, can also shine the specific part of laboratory mouse, improves the accuracy of experimental efficiency and experiment.

Description

Experimental device for be used for shining laboratory mouse
Technical Field
The invention relates to the technical field of experimental appliances, in particular to an experimental device for irradiating an experimental mouse.
Background
Phototherapy is a method of preventing and treating diseases and promoting the recovery of the body by using sunlight or artificial light. Sunlight therapy has been classified into the category of recuperation, and light therapy in physiotherapy is a method of preventing and treating diseases using artificial light radiation. Phototherapy is classified into infrared therapy, visible light therapy and ultraviolet therapy according to the wavelength of light used. From the coherence of the light, incoherent light and coherent light therapy can be divided, and from the light source used natural light and artificial light therapy can be divided. Photochemotherapy, methods of photosensitizing cancer diagnosis and new methods of treatment of neonatal jaundice with bluish violet light have emerged since 1970. Therefore, the phototherapy has important medical value for preventing and treating diseases and preventing health care. Modern scientific research shows that sunlight mainly contains three rays, namely ultraviolet rays, infrared rays and visible light. Wherein: the skin can be healthy when ultraviolet rays cannot be seen by naked eyes, the hematopoietic function of an organism can be stimulated, the immunity of the organism can be improved, the sugar metabolism in vivo can be improved, the calcium and phosphorus metabolism and the synthesis of vitamin D in vivo can be promoted, the osteomalacia or rickets can be effectively prevented, the blood circulation can be promoted, the appetite can be promoted, and the physique can be enhanced; similarly, the infrared ray is also an invisible ray which accounts for 60-70% of sunlight, can permeate skin to subcutaneous tissues and has the function of thermal stimulation on human bodies, thereby expanding blood vessels, accelerating blood circulation, promoting metabolism in the bodies and playing the roles of diminishing inflammation and easing pain; the visible light can regulate human emotion, revivify, improve human life pleasure and work efficiency, and improve various physiological functions of human body. At present, the light regulation effect and the molecular mechanism are only developed at one corner of the iceberg, and the light acts on different body parts to generate different physiological effects, so that the new light regulation effect and the molecular mechanism still need to be explored and clarified. The progress of these works will help us to utilize light better, explore the potential health care value of illumination to the organism, explore the potential risk, make this technology safer and more effective, and then benefit mankind extensively.
One of the most critical parts is animal experiments, and it has been reported that phototherapy has been applied to the research of various animal models such as myopia, hearing impairment, atherosclerosis, neurodegenerative diseases, alopecia, tumor and trauma, and has been prevented, alleviated and treated to various degrees at the present stage. Meanwhile, the selection of experimental animals is also important, and in view of strong reproductive capacity, short reproductive cycle, similar physiological, biochemical and development processes and human beings, and 98 percent homology of genome and human beings, a plurality of experimental mouse disease models can basically simulate the occurrence and development processes of human diseases, so that the experimental mice become the second choice of most experimental animals.
However, due to its small size and high mobility, area selectivity and continuous illumination capability during illumination become major problems to be overcome. The device and the equipment that shine and handle experimental animals are lacked in the market today, and the device that shines that the laboratory used is mostly the self-control type, has the precision poor, can't adjust intensity, frequency and angle, shortcoming such as repeatability is poor. Such non-standardized or non-standardized illumination treatments may result in experiments that are not phenomenal or even lead to erroneous conclusions.
Disclosure of Invention
Aiming at the technical problems in the prior art, the invention aims to provide an experimental device for irradiating a laboratory mouse. The experimental device can accurately and controllably irradiate the experimental mouse, and the irradiation area can be conveniently adjusted.
In order to achieve the purpose, the invention adopts the following technical scheme:
the utility model provides an experimental apparatus for be used for shining laboratory mouse, includes shell, backup pad and is used for placing the box body of laboratory mouse, shell and backup pad fixed connection, the inner wall of shell is equipped with the guide slot, the outer wall of box body be equipped with guide slot complex arch, the box body is located the shell, and box body and shell sliding connection, the outer wall of shell is equipped with the lamp, the shell is equipped with the adjustment mechanism who is used for adjusting the lamp.
Preferably, the adjusting mechanism comprises an adjusting rod, a spherical part and a lamp holder, the adjusting rod is connected with the upper end of the spherical part, the spherical part is connected with the shell, the lower end of the spherical part is connected with the lamp holder, and the lamp holder is connected with the irradiation lamp.
Preferably, a magnet is embedded in the housing, and the spherical part is slidably connected with the housing through the magnet.
Preferably, the surface of the spherical part is made of a magnetic material.
Preferably, the box body includes clip and the casing that is used for fixed laboratory mouse, along the center pin direction of casing is equipped with the spout of bar, clip and spout sliding connection.
Preferably, the clip includes handle and clamping part, the handle is triangle-shaped, the clamping part is the arch, the handle is connected with the clamping part, handle and spout sliding connection.
Preferably, the clip is made of an elastic material.
Preferably, the shell and the box body are both in the shape of an annular body, connecting plates are oppositely arranged in the shell, and the connecting plates support the bulges of the box body.
Preferably, the experimental device further comprises a light source parameter control box, and the light source parameter control box is connected with the irradiation lamp.
Preferably, the lamps use different wavelength light sources.
Compared with the prior art, the invention has the following advantages and beneficial effects:
1. the invention relates to an experimental device for irradiating an experimental mouse, wherein a shell of the experimental device is fixedly connected with a supporting plate, the inner wall of the shell is provided with a guide groove, the outer wall of a box body is provided with a bulge matched with the guide groove, the box body is positioned in the shell and is in sliding connection with the shell, the outer wall of the shell is provided with an irradiation lamp, and the shell is provided with an adjusting mechanism for adjusting the angle of the irradiation lamp; adopt the adjustment mechanism of adjustable lamp angle, make the irradiation efficiency of laboratory mouse improve, adjust the irradiation area, convenient operation, accommodation is wide, can also shine the specific part of laboratory mouse, improves the accuracy of experimental efficiency and experiment.
2. The invention relates to an experimental device for irradiating experimental mice, wherein a magnet is embedded in a shell of the experimental device, a spherical part is connected with the shell in a sliding manner, different tangent planes are attracted with the magnet by rotating the spherical part through an adjusting rod, so that the spherical part rotates to adjust a lamp holder to drive an upper irradiation lamp to adjust the angle, the stability can be considered, and the flexibility is increased.
3. The invention relates to an experimental device for irradiating a laboratory mouse, wherein a box body of the experimental device comprises a clamp and a shell for fixing the laboratory mouse, a strip-shaped sliding groove is arranged along the central axis direction of the shell, the clamp is in sliding connection with the sliding groove, the laboratory mouse is clamped through the clamp, and then the clamping groove is placed to push the inside of the box body, so that the laboratory mouse is more convenient to grab, and the convenience of the experiment is improved.
4. The experimental device for irradiating the experimental mouse further comprises a light source parameter control box, wherein the light source parameter control box is connected with the irradiation lamp, and the light source parameter control box is adopted to control the light source intensity, the irradiation frequency and the irradiation time of the irradiation lamp, so that experimental personnel can record experimental data conveniently, and the experimental data are more scientific and accurate.
5. The experimental device for irradiating the experimental mouse is characterized in that the irradiation lamps of the experimental device adopt lamp sources with different wavelengths, the irradiation lamps with different wavelengths can be selected and installed according to experimental needs, the experiment is more flexible, and the application range of the experimental device is wider.
Drawings
FIG. 1 is a schematic view of an experimental apparatus for irradiating a laboratory mouse according to the present invention.
FIG. 2 is a schematic diagram of a cartridge of the experimental apparatus for irradiating laboratory mice according to the present invention.
FIG. 3 is a schematic view of an adjusting mechanism of the experimental apparatus for irradiating a laboratory mouse according to the present invention.
The portable electronic device comprises a shell 1, a connecting plate 11, an adjusting mechanism 12, a spherical part 121, an adjusting rod 122, a magnet 123, a lamp holder 124, a lamp 125, a supporting plate 2, a box 3, a clamp 31, a handle 311, a clamping part 312, a protrusion 32, a sliding groove 33, a light source parameter control box 4, an electric wire 41 and a charger 5.
Detailed Description
The following describes the object of the present invention in further detail with reference to the drawings and specific examples, which are not repeated herein, but the embodiments of the present invention are not limited to the following examples.
As shown in fig. 1 to 3, an experimental apparatus for irradiating a laboratory mouse includes a housing 1, a support plate 2 and a case 3 for placing a laboratory mouse, the shell 1 is fixedly connected with the supporting plate 2, the inner wall of the shell 1 is provided with a guide groove, the outer wall of the box body 3 is provided with a bulge 32 matched with the guide groove, the box body 3 is positioned in the shell 1, and the box body 3 is connected with the shell 1 in a sliding way, and the bulge 32 is matched with the guide groove, so that the box body 3 and the shell 1 can be conveniently installed and detached, the outer wall of shell 1 is equipped with lamp 125, shell 1 is equipped with the adjustment mechanism 12 that is used for adjusting lamp 125 angle, adopts the adjustment mechanism 12 of adjustable lamp 125 angle, makes the illuminating efficiency of laboratory mouse improve, adjusts the irradiation area, convenient operation, and accommodation is wide, can also shine the specific part of laboratory mouse, improves the accuracy of experimental efficiency and experiment.
The adjusting mechanism 12 comprises an adjusting rod 122, a spherical part 121 and a lamp holder 124, wherein the adjusting rod 122 is connected with the upper end of the spherical part 121, the spherical part 121 is connected with the shell 1 in a sliding way, the shell 1 is provided with a plurality of mounting holes for mounting the spherical part 121, a plurality of irradiation lamps 125 can be mounted according to the experimental requirement, the lower end of the spherical part 121 is connected with the lamp holder 124, and the lamp holder 124 is connected with the irradiation lamps 125; the lamp holder 124 is adopted to facilitate the replacement of the damaged irradiation lamp 125, the adjusting rod 122 is pulled to rotate the spherical part 121, so that the irradiation angle of the irradiation lamp 125 is adjusted, and the spherical part 121 is kept movably connected with the housing 1 through an arc spherical surface.
The embedded magnet 123 that has of shell 1, spherical portion 121 passes through magnet 123 and is connected with shell 1, adopts magnet 123 to make spherical portion 121 rotation regulation lamp stand 124, lets different tangent planes and magnet 123 attract each other through rotating spherical portion 121, drives the above-mentioned irradiation lamp 125 angle of adjustment, both can compromise stability and have increased the flexibility. The surface of the spherical part 121 is made of magnetic material, and the surface of the spherical part 121 is attracted with the magnet 123, so that the flexibility of the spherical part 121 is further increased.
The box body 3 comprises a clamp 31 for fixing a laboratory mouse and a shell, the shell is made of high-light-transmittance materials, a strip-shaped sliding groove 33 is formed in the shell along the direction of a central shaft of the shell, the clamp 31 is in sliding connection with the sliding groove 33, and the strip-shaped sliding groove 33 is beneficial to taking out and putting in the laboratory mouse; clip the laboratory mouse through clip 31, then place spout 33 internal thrust to the inner chamber of box body 3, make the snatching of laboratory mouse more convenient, increased the convenience of experiment. The material of the shell has certain hardness and higher light transmittance, especially under the condition that the experimental mouse has higher requirement on the light transmittance.
The clip 31 includes a handle 311 and a clamping portion 312, the handle 311 is triangular, the clamping portion 312 is arched, the handle 311 is connected with the clamping portion 312, and the handle 311 is connected with the sliding groove 33 in a sliding manner. When the laboratory mouse is fixed, an experimenter grasps the tail of the laboratory mouse with the left hand, and clamps the neck of the laboratory mouse with the clamp 31 by the right hand while keeping the body stretched by breaking away forwards, and the pinch handle 311 keeps the clamp 31 in a tightened state; the other clamp 31 is taken up by the left hand, the back part of the abdomen of the experimental rat is clamped, and the clamping part 312 of the experimental rat clamp is also tightened; the laboratory mouse is lifted by both hands, and the handles 311 of the clips 31 are sequentially fed into the box body 3 in the order of head and tail, and are fixed in the sliding grooves 33 of the box body 3, so that the laboratory mouse is fed into the box body 3. After the laboratory mouse is fixed, the power supply is switched on, the light source parameter control box 4 is adjusted according to the requirements, the light source of the illuminating lamp 125 corresponding to the part of the laboratory mouse to be illuminated is turned on, various parameters of the light source are adjusted, the adjusting rod 122 is shifted to focus the light of the illuminating lamp 125 on the part of the laboratory mouse to be illuminated, and the illumination experiment is started. The device has reasonable design, convenient operation and wide application range; the light irradiation can be accurately and controllably carried out on the specific part of the experimental mouse, and the experimental efficiency and accuracy are improved.
The clamp 31 is made of an elastic material, the contact surface of the clamp 31 and the experimental mouse is made of an elastic and flexible material, the experimental mouse can be well protected by the elastic and flexible material, the experimental mouse is not damaged by clamping, and the clamp 31 is ensured to have certain tensile strength and bending strength, so that the continuity of the experiment is facilitated; the experimental device has two clamps 31, the neck and the back of the abdomen of the laboratory mouse are respectively clamped, the laboratory mouse is well fixed, and the clamps 31 have flexibility and firmness.
Shell 1 and box body 3 all adopt the annular body shape, be provided with connecting plate 11 in the shell 1 relatively, connecting plate 11 supports the arch 32 of box body 3, adopts connecting plate 11 can adjust the distance between box body 3 and the shell 1, can also adopt not the connecting plate 11 of equidimension according to the experiment purpose of difference simultaneously, adjusts the irradiation distance according to the experiment needs to reach the experiment purpose.
The experimental device further comprises a light source parameter control box 4, the light source parameter control box 4 is connected with the illuminating lamp 125 through an electric wire 41, the light source parameter control box 4 can be adjusted according to requirements, various parameters of a light source are adjusted, different experimental requirements are met, the light source parameter control box 4 is further provided with a charger 5, the light source parameter control box 4 is conveniently charged, the light source intensity of the illuminating lamp 125 is controlled by the light source parameter control box 4, the illuminating frequency, the illuminating time and the like, experimental personnel can conveniently record experimental data, and the experimental data are scientific and accurate.
The lamps 125 adopt lamp sources with different wavelengths, so that different irradiation requirements of the experimental mouse are met, the lamps 125 with different wavelengths can be selected and installed according to the experimental requirements, the experiment is more flexible, and the application range of the experimental device is wider.
The above-mentioned embodiments are preferred embodiments of the present invention, and the present invention is not limited thereto, and any other modifications or equivalent substitutions that do not depart from the technical spirit of the present invention are included in the scope of the present invention.

Claims (10)

1. The utility model provides an experimental apparatus for be used for shining laboratory mouse, its characterized in that includes shell, backup pad and the box body that is used for placing laboratory mouse, shell and backup pad fixed connection, the inner wall of shell is equipped with the guide slot, the outer wall of box body be equipped with guide slot complex arch, the box body is located the shell, and box body and shell sliding connection, the outer wall of shell is equipped with the lamp, the shell is equipped with the adjustment mechanism who is used for adjusting the lamp.
2. The experimental device for irradiating a laboratory mouse according to claim 1, wherein said adjusting mechanism comprises an adjusting rod, a spherical portion and a lamp holder, said adjusting rod is connected with the upper end of the spherical portion, said spherical portion is connected with the housing, the lower end of the spherical portion is connected with the lamp holder, said lamp holder is connected with the irradiation lamp.
3. The laboratory device according to claim 2, wherein a magnet is embedded in the housing, and the spherical portion is slidably connected to the housing via the magnet.
4. The experimental device for irradiating laboratory mice as claimed in claim 3, wherein the surface of said spherical portion is made of a magnetic material.
5. The experimental device for irradiating laboratory mice as claimed in claim 1, wherein said box body comprises a clip for fixing laboratory mice and a housing, a strip-shaped sliding groove is provided along a central axis direction of said housing, and said clip is slidably connected with said sliding groove.
6. The experimental device for irradiating laboratory mice as claimed in claim 5, wherein said clip comprises a handle and a clamping portion, said handle is triangular, said clamping portion is arched, said handle is connected with said clamping portion, said handle is slidably connected with said sliding groove.
7. The laboratory device according to claim 6, wherein said clip is made of an elastic material.
8. The experimental facility for irradiating laboratory mice as claimed in claim 1, wherein said housing and said box body are each in the shape of a ring, and a connecting plate is oppositely disposed in said housing, and said connecting plate supports the protrusion of the box body.
9. The experimental device for irradiating laboratory mice as claimed in claim 1, further comprising a light source parameter control box, wherein the light source parameter control box is connected with an irradiation lamp.
10. The experimental facility for irradiating laboratory mice as claimed in claim 9, wherein said irradiation lamp employs light sources of different wavelengths.
CN202111416324.XA 2021-11-25 2021-11-25 Experimental device for be used for shining laboratory mouse Pending CN114009353A (en)

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CN202111416324.XA CN114009353A (en) 2021-11-25 2021-11-25 Experimental device for be used for shining laboratory mouse

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CN202111416324.XA CN114009353A (en) 2021-11-25 2021-11-25 Experimental device for be used for shining laboratory mouse

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CN114009353A true CN114009353A (en) 2022-02-08

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Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005261460A (en) * 2004-03-16 2005-09-29 Teijin Pharma Ltd Animal fixing base
CN201987699U (en) * 2011-03-04 2011-09-28 苏州大学 Fixing device for rat irradiation experiment
CN204259319U (en) * 2014-11-07 2015-04-08 中国农业科学院农产品加工研究所 A kind of ultraviolet irradiation experiment protective housing
CN105311754A (en) * 2015-10-14 2016-02-10 苏州大学 Beta ray quantitative skin irradiation experimental facility
CN107711542A (en) * 2017-11-14 2018-02-23 天津开发区合普工贸有限公司 A kind of quick light poison experiment shield cage of toy
JP2019071974A (en) * 2017-10-12 2019-05-16 日本クレア株式会社 Retainer for laboratory animal
CN208876878U (en) * 2017-12-15 2019-05-21 山东省食品药品检验研究院 A kind of skin phototoxicity experiment instrument
CN209172570U (en) * 2018-03-06 2019-07-30 河南应用技术职业学院 A kind of pharmaceutical test rat holder
KR20190090165A (en) * 2018-01-24 2019-08-01 이두열 Angle control light stand
CN210314289U (en) * 2019-06-28 2020-04-14 陕西慧康生物科技有限责任公司 Ultraviolet irradiation equipment for building UV stimulation model
CN210800896U (en) * 2019-12-03 2020-06-19 武汉亮节科技有限公司 LED light projecting lamp screen with adjustable light projecting angle
CN111714788A (en) * 2020-06-19 2020-09-29 广州医科大学附属肿瘤医院 Animal irradiation experimental apparatus
CN213190272U (en) * 2020-04-23 2021-05-14 北京慧荣和科技有限公司 Open type rat fixing cylinder
CN213746416U (en) * 2020-11-11 2021-07-20 南京和光科技有限公司 LED projecting lamp convenient to adjust light angle

Patent Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005261460A (en) * 2004-03-16 2005-09-29 Teijin Pharma Ltd Animal fixing base
CN201987699U (en) * 2011-03-04 2011-09-28 苏州大学 Fixing device for rat irradiation experiment
CN204259319U (en) * 2014-11-07 2015-04-08 中国农业科学院农产品加工研究所 A kind of ultraviolet irradiation experiment protective housing
CN105311754A (en) * 2015-10-14 2016-02-10 苏州大学 Beta ray quantitative skin irradiation experimental facility
JP2019071974A (en) * 2017-10-12 2019-05-16 日本クレア株式会社 Retainer for laboratory animal
CN107711542A (en) * 2017-11-14 2018-02-23 天津开发区合普工贸有限公司 A kind of quick light poison experiment shield cage of toy
CN208876878U (en) * 2017-12-15 2019-05-21 山东省食品药品检验研究院 A kind of skin phototoxicity experiment instrument
KR20190090165A (en) * 2018-01-24 2019-08-01 이두열 Angle control light stand
CN209172570U (en) * 2018-03-06 2019-07-30 河南应用技术职业学院 A kind of pharmaceutical test rat holder
CN210314289U (en) * 2019-06-28 2020-04-14 陕西慧康生物科技有限责任公司 Ultraviolet irradiation equipment for building UV stimulation model
CN210800896U (en) * 2019-12-03 2020-06-19 武汉亮节科技有限公司 LED light projecting lamp screen with adjustable light projecting angle
CN213190272U (en) * 2020-04-23 2021-05-14 北京慧荣和科技有限公司 Open type rat fixing cylinder
CN111714788A (en) * 2020-06-19 2020-09-29 广州医科大学附属肿瘤医院 Animal irradiation experimental apparatus
CN213746416U (en) * 2020-11-11 2021-07-20 南京和光科技有限公司 LED projecting lamp convenient to adjust light angle

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