CN113994954A - Organ in-vitro perfusion device - Google Patents
Organ in-vitro perfusion device Download PDFInfo
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- CN113994954A CN113994954A CN202111509615.3A CN202111509615A CN113994954A CN 113994954 A CN113994954 A CN 113994954A CN 202111509615 A CN202111509615 A CN 202111509615A CN 113994954 A CN113994954 A CN 113994954A
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- 210000000056 organ Anatomy 0.000 title claims abstract description 132
- 230000010412 perfusion Effects 0.000 title claims abstract description 68
- 238000000338 in vitro Methods 0.000 title abstract description 4
- 239000007788 liquid Substances 0.000 claims description 31
- 230000001079 digestive effect Effects 0.000 claims description 13
- 239000012535 impurity Substances 0.000 claims description 7
- 229910052760 oxygen Inorganic materials 0.000 claims description 6
- 239000001301 oxygen Substances 0.000 claims description 6
- 208000007536 Thrombosis Diseases 0.000 claims description 5
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 5
- 238000001914 filtration Methods 0.000 claims description 5
- 238000004659 sterilization and disinfection Methods 0.000 claims description 4
- 230000001706 oxygenating effect Effects 0.000 claims description 3
- 238000012549 training Methods 0.000 description 31
- 241001465754 Metazoa Species 0.000 description 13
- 210000004204 blood vessel Anatomy 0.000 description 8
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- 108010066057 cabin-1 Proteins 0.000 description 5
- 239000000082 organ preservation Substances 0.000 description 5
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Images
Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0236—Mechanical aspects
- A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
- A01N1/0247—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components for perfusion, i.e. for circulating fluid through organs, blood vessels or other living parts
Abstract
The invention discloses an organ in vitro perfusion device, which comprises: an organ chamber (1) for accommodating an isolated organism organ (2); a perfusion pipeline (4) which comprises a main pipeline (4-1) and branch pipelines (4-2) with different pipe diameters and perfuses the organism organ (2); the adjustable pipe clamp (5) is arranged on the branch pipeline (4-2) and is used for adjusting the pressure and the flow; a pump (3) which generates perfusion power for perfusing the living organ (2) through the perfusion line (4). The device of the invention can perfuse the isolated organ of the organism, maintain the vitality of the organ, and can perfuse a plurality of organism organs simultaneously by using a single pump. The invention generates different accurate pressures and flows needed by a plurality of organs through the branch pipelines and the adjustable pipe clamps, obviously simplifies the structure of the device, and improves the overall performances such as safety, stability, portability and the like.
Description
Technical Field
The invention relates to medical equipment, in particular to a mechanical perfusion type organ preservation device which is mainly suitable for medical training and organ preservation.
Background
At present, the medical training mostly adopts a virtual reality technology, has the defects of lack of reality and the like, and is only suitable for primary entry training, and the middle-level medical training needs live large animals or organs for training. In the medical training process, in order to ensure that the training effects of surgical laparoscopes, natural orifice endoscopes, surgical robots, medical digestive endoscopes and the like are more real, large animals are required to be used for medical training. However, the establishment of a large animal operating room requires special sites and qualification, and also requires special anesthesiologists, instrument nurses, managers and the like, so that the cost is high; the cost for purchasing living animals is high, and the management risk of narcotic dangerous goods is also involved; with the progress of social civilization, the ethical examination and approval is increasingly strict; more importantly, live animal experiments are at risk of disease transmission, and all of the factors limit the large-scale popularization of medical training by using large animals.
The method adopts a real animal isolated organ which has real means such as blood supply, complete organ clusters, focus building and the like. The real visual and tactile feedback is ensured, and the real human organs can be highly simulated from the structure of the tissue. Provides a high-simulation operation training environment for the trained doctor. Meanwhile, the isolated organ training has simple requirements on fields and personnel, is convenient to obtain materials, and provides conditions for daily chemical training. In addition, when medical equipment such as high frequency electrotome, supersound sword demonstrates, in order to let the customer experience the equipment effect better, more truly imitate human body environment, it is more convenient portable, reduce the show cost, also need use true animal organ. By using the mechanical perfusion preservation technology, the organ vitality can be maintained for a long time, and the pulsating bleeding of blood vessels can be simulated.
Chinese patent application 201580002264.3 discloses a human body simulation device, comprising: an organ from an animal having a biological tissue and a blood vessel extending from the biological tissue; a blood reservoir portion for storing blood to be sent to the blood vessel; a tube connecting the blood vessel and the blood reservoir; a pump section provided in the middle of the tube and configured to transport blood from the blood reservoir section to the blood vessel; and a storage unit that stores the organ, humidifies the organ by supplying vapor having a temperature higher than room temperature to the organ, and sets the organ to a temperature of 20-50 ℃.
Chinese utility model patent 201420114300.8 discloses a high emulation intervention operation training ware, a serial communication port, include: a dummy unit having an abdominal cavity; an animal viscera disposed in the abdominal cavity of the dummy human unit; an auxiliary pipeline connected with the animal viscera; a blood collection reservoir connected to the auxiliary conduit to supply and recover perfusate; and a pump unit arranged between the blood collecting pool and the auxiliary pipeline and used for providing perfusion fluid circulation driving force.
Disclosure of Invention
Aiming at the problems in the background technology, the invention discloses a mechanical perfusion organ preservation device which is suitable for medical training and organ preservation, and mainly comprises laparoscope training, surgical robot training, digestive endoscopy training, ureteroscope training and the like.
The mechanical perfused organ preservation apparatus of the present invention comprises: an organ chamber for accommodating an isolated organism organ; the perfusion pipeline comprises a main pipeline and branch pipelines with different pipe diameters, and perfuses the organism organ; the adjustable pipe clamp is arranged on the branch pipeline and used for adjusting the pressure and the flow; and a pump for generating perfusion power to perfuse the organism organ through the perfusion line.
Optionally, the organ ex vivo perfusion apparatus further comprises: the liquid storage bin is used for storing circulating perfusion liquid, and a micro-bubble generator is arranged in the liquid storage bin and used for generating oxygen micro-bubbles.
Optionally, the branch line ends with side holes.
Optionally, the organ in vitro perfusion device is provided with a temperature maintaining device (7) for maintaining the temperature of the organism organ and the circulating liquid; the oxygenator (11) is arranged on the perfusion pipeline and is used for continuously oxygenating the circulating perfusion liquid; and the thrombus filter is arranged on the perfusion pipeline and used for filtering impurities in the circulating perfusion fluid.
Optionally, there is a filter screen structure inside the organ chamber for filtering impurities.
Optionally, the lower portion of the organ chamber is funnel-shaped or hemispherical in shape, such that the circulating perfusate is at the lowest point of the organ chamber when the organ chamber is rotated.
Optionally, a laparoscope instrument inlet and a digestive endoscope inlet are arranged on the organ chamber, and a lighting device, a disinfection system and a diaphragm-imitating structure are arranged in the organ chamber.
Optionally, a surgical instrument hanger is arranged on the side surface of the organ cabin and used for hanging surgical instruments.
Optionally, the organ ex vivo perfusion apparatus further comprises: the operation plane, the organ storehouse is placed on the operation plane, has the lift post below the organ storehouse, can go up and down the operation plane, is provided with universal auxiliary stand on the operation plane for fixed peritoneoscope hard mirror.
Optionally, the organ ex vivo perfusion apparatus further comprises: the main machine cabin is arranged below the organ cabin and is of a multilayer structure and used for accommodating the laparoscope main machine, the digestive endoscope main machine, the high-frequency electrotome and the cold light source.
Optionally, the organ perfusion apparatus ex vivo further comprises: the universal supporting structure is positioned inside or below the organ bin and can adjust the placing angle and position of the organ bin;
optionally, the organ perfusion apparatus ex vivo further comprises: and the negative plate is positioned at the bottom of the organ bin and provides a loop for the electric energy platform.
Optionally, the organ perfusion apparatus ex vivo further comprises: a display and a support connected with the endoscope to display the operation image.
The invention generates different accurate pressures and flows needed by a plurality of organs through the branch pipelines and the adjustable pipe clamps, obviously simplifies the structure of the device, and improves the overall performances such as safety, stability, portability and the like. The perfusion pipeline is divided into a main pipeline and branch pipelines, the organism organs are perfused under the driving of the pump, and the branch pipelines form different pressures and flows according to different pipe diameters.
The invention utilizes the single pump to fill the branch pipelines, avoids the defect that the branch pipelines are filled by a plurality of pumps, obviously simplifies the structure of the device and improves the stability. Firstly, forming different flow rates by branch pipelines according to different pipe diameters; and secondly, the pipe clamp can be adjusted to further accurately adjust the pressure and the flow of the branch pipeline, and the pipe clamp is arranged on the branch pipeline with a thicker pipe diameter, so that the perfusion flow and the pressure of the thicker pipeline are directly reduced, and the flow and the pressure of the thinner pipeline are improved. Because the teaching and training device needs to use a centrifugal pump, the centrifugal pump has the lowest flow limit. Therefore, the branch pipeline of the invention can be used for shunting low flow from the branch pipeline, is more suitable for perfusion of a centrifugal pump, and is also suitable for perfusion of low flow or small organs. While the flow of the other branch lines improves the circulation efficiency.
The invention utilizes the mechanical perfusion principle to perfuse the viscera of the large animal, continuously maintains the activity of the viscera, is used for medical training, obviously reduces the cost, improves the training effect, is convenient to operate and use, and avoids the sacrifice of a large number of experimental animals. The laparoscopic instrument entry can be used to training such as laparoscopic training operation robot, and the digestive endoscopy entry can be used to digestive endoscopy training, still includes urinary system scope entry, hysteroscope entry etc.. The device is matched with corresponding teaching software, action evaluation software, a grouping platform and the like.
The invention utilizes the mechanical perfusion device to perfuse the viscera of the large animals from slaughter houses, continuously maintains the activity of the viscera, is used for medical training, obviously reduces the cost, improves the training effect, is convenient to operate and use, avoids the sacrifice of a large number of experimental animals, avoids ethical examination and effectively reduces the risk of disease transmission. The device is matched with corresponding teaching software and action evaluation software, and has an international advanced level.
Drawings
In order that the invention may be more readily understood, it will be described in more detail with reference to specific embodiments thereof that are illustrated in the accompanying drawings. These drawings depict only typical embodiments of the invention and are not therefore to be considered to limit the scope of the invention.
FIG. 1 is a schematic diagram of the basic structure of the device of the present invention.
FIG. 2 is a schematic diagram of the basic structure of the device of the present invention
Fig. 3 is a schematic diagram of the basic structure of the device of the present invention for a low flow perfusion mode.
Fig. 4 is a schematic view of a liquid storage chamber and a microbubble generator of the apparatus of the present invention.
Fig. 5 is a schematic view of a complementary structure of the device of the present invention.
Fig. 6 is an oblique view of a first embodiment of the device of the present invention.
Figure 7 is a side view of a first embodiment of the device of the present invention.
FIG. 8 is a side sectional view of a first embodiment of the device of the present invention.
Fig. 9 is a top view of a first embodiment of the apparatus of the present invention.
Fig. 10 is an oblique view of a second embodiment of the device of the present invention.
Figure 11 is a side view of a second embodiment of the device of the present invention.
FIG. 12 is a top view of a second embodiment of the apparatus of the present invention.
FIG. 13 is a basic block diagram of a third embodiment of the apparatus of the present invention.
FIG. 14 is a supplementary structural view of a first embodiment of the apparatus of the present invention.
Reference numerals
1-organ chamber, 2-organism organ, 3-pump, 4-perfusion tube, 4-1 main tube, 4-2 branch tubes, 5-adjustable tube clamp, 6-side hole, 7-temperature maintaining device, 8-filter screen, 9-liquid storage chamber, 10-micro bubble generator, 11-oxygenator, 12-liquid storage chamber inflow port, 13-liquid storage chamber outflow port, 14-surgical instrument hanger, 15-laparoscope instrument inlet, 16-digestive endoscope inlet, 17-lighting device, 18-main machine chamber, 19-laparoscope main machine, 20-embolus filter, 21-digestive endoscope main machine, 22-high frequency electrotome, 23-cold light source, 24-lifting column, 25-funnel type or hemispherical drainage structure, 26-universal support structure, 27-display and support, 28-diaphragm-simulated structure, 29-negative plate, 30-ultraviolet lamp disinfection system, 31-oxygen generator, 32-universal auxiliary support and 33-front door.
Detailed Description
Embodiments of the present invention will now be described with reference to the drawings, wherein like parts are designated by like reference numerals. The embodiments described below and the technical features of the embodiments may be combined with each other without conflict.
Basic structure
As shown in fig. 1 and 2, the apparatus of the present invention comprises a biological organ 2, an organ chamber 1, a pump 3, a perfusion line 4, a temperature maintenance device 7 and an adjustable tube clamp 5.
The organism organ 2 can be organ cluster or individual organ, has collateral blood vessel, is placed in the organ chamber 1, and is maintained at the temperature of organism organ 2 and circulation liquid by the temperature maintaining device 7, preferably, the temperature is reduced to reduce organ inactivation speed, reduce bacteria reproduction speed, and maintain the organism organ 2 in a fresh state for a long time. A pump 3, preferably a centrifugal pump, generates perfusion power for perfusing the biological organ 2 through the perfusion line 4 and the accessory blood vessels.
The perfusion pipeline 4 comprises a main pipeline 4-1 and a plurality of branch pipelines 4-2, wherein the tail end of the main pipeline 4-1 is divided into two or more branch pipelines 4-2, the branch pipelines 4-2 are respectively connected with blood supply vessels of different organs according to different thicknesses, different flow rates are formed according to different pipe diameters, the flow rate is small when the pipe diameter is thin, and the flow rate is large when the pipe diameter is thick. The branch pipeline 4-2 is provided with an adjustable pipe clamp 5, the adjustable pipe clamp 5 further accurately adjusts the pressure and the flow of the branch pipeline 4-2, the adjustable pipe clamp 5 is arranged on the branch pipeline 4-2 with a thicker pipe diameter, the branch pipeline 4-2 is extruded in different degrees or the sectional area of the branch pipeline 4-2 is reduced for flow limiting, the perfusion flow and the pressure of the branch pipeline 4-2 with the thicker pipe diameter are directly reduced, and the flow and the pressure of the branch pipeline 4-2 with the finer pipe diameter are improved.
After flowing out from the organism organ 2, the circulating perfusate firstly passes through the organ bin 1, a filter screen 8 is arranged in the organ bin 1, impurities such as thrombus, tissue fragments and the like of the circulating perfusate are filtered, and then the circulating perfusate is gathered in a liquid storage bin 9 and stored.
As shown in FIG. 3, for single organs with small blood flow, such as pancreas, limbs, kidney, etc., low flow can be branched off from one of the branch lines 4-2 by using the branch line 4-2 due to flow restriction, which is more suitable for centrifugal pump perfusion, and is also suitable for low flow perfusion or small organs. Meanwhile, the flow of other branches of the branch pipeline 4-2 improves the circulation and oxygenation efficiency and maintains the temperature stability.
As shown in fig. 4, the apparatus of the present invention further comprises a microbubble generator 10, and the microbubble generator 10 is located inside the reservoir 9. The microbubble generator 10 is a porous structure, and generates oxygen microbubbles from the input oxygen, so as to improve the oxygen content of the circulating perfusate and reduce the carbon dioxide content. The liquid storage bin 9 comprises a liquid storage bin inflow port 12 and a liquid storage bin outflow port 13, the liquid storage bin inflow port 12 is used for inflow and supplement of circulating perfusion liquid, and the liquid storage bin outflow port 13 is used for outflow of circulating liquid or discharge of waste liquid.
As shown in fig. 5, the end of the branch line 4-2 is provided with a side hole 6, which can realize accurate perfusion corresponding to different blood vessel branches. The device of the invention further comprises an oxygenator 11 and a embolectomy filter 20, the oxygenator 11 being arranged in the perfusion line, in the embodiment shown in the figures between the pump 3 and the embolectomy filter 20, for continuously oxygenating the circulating perfusion fluid. The thrombus filter 20 is used for filtering impurities such as thrombus, tissue fragments, air bubbles and the like of the circulating perfusate.
First embodiment-teaching training device
Fig. 6-9, fig. 14 show a first embodiment of the device of the invention, an organ perfusion device for educational training. The basic principle follows the part described above with reference to fig. 1-5.
As shown in fig. 6-9, the apparatus of the present invention further comprises a display and support 27 for displaying an operation image or a software interface. The upper part of the organ bin 1 is provided with a laparoscope instrument inlet 15 and a digestive endoscope inlet 16, and the laparoscope instrument inlet 15 is a laparoscope surgical instrument channel; the digestive endoscope inlet 16 is a digestive endoscope channel which is communicated with the organ chamber 1 to operate and train the organism organ 2 in the organ chamber 1. Preferably, inside the organ chamber 1 there is an illumination means 17. The organ storehouse 1 side surgical instruments hanging frame 14 is used for hanging surgical instruments, and is convenient to operate. The lower part of the rear part of the organ chamber 1 is provided with a liquid storage chamber 9 for storing circulating perfusate and is convenient to clean. The main machine cabin 18 is arranged below the organ cabin 1, the main machine cabin 18 is of a multilayer structure, and the accommodation and fixation are not limited to active components such as a laparoscope main machine 19, a digestive endoscope main machine 21, a high-frequency electric knife 22, a cold light source 23 and the like. The main engine compartment 18 has a front door 33 for quick opening and closing of the main engine compartment 18. The lower part of the organ cabin 1 is provided with a lifting column 24 which can lift and lower an operation plane and is used for adapting to operators with different heights. The temperature maintaining device 7 is located around or inside the organ container 1 and is used for maintaining the temperature of the living organ 2 and the circulating fluid. The pump 3 is located below the reservoir 9.
As shown in fig. 14, the device of the present invention further comprises a universal support structure 26, wherein the universal support structure 26 is located inside the organ container 1, and the angle of the organ container 1 can be flexibly adjusted. Preferably, the lower part of the organ bin 1 is provided with a funnel-shaped or hemispherical drainage structure 25 for storing the circulating perfusate liquid, the circulating perfusate liquid is positioned at the lowest point of the organ bin 1, and when the angle of the organ bin 1 is changed, the circulating perfusate liquid can still be drained or guided normally, the liquid level height is kept, and the risk of air suction is reduced. The inside of the organ bin 1 is provided with a diaphragm-imitating structure 28 which can restore the anatomical structure in the human body and lift and fix the liver. The bottom of the organ cabin 1 is a negative plate 29 which provides a loop for an electric energy platform such as a high-frequency electric knife and an ultrasonic knife. Within the organ chamber 1 is a disinfection system 30, preferably ultraviolet light, for reducing bacterial growth within the organ chamber and within the animal's organs.
Second embodiment-teaching and training apparatus
Fig. 10-12 show a second embodiment of the invention, also in the form of an organ perfusion apparatus for educational training. The basic principle follows the part described above with reference to fig. 1-5. Which differs from the first embodiment in the shape of the main housing 18 and the position of the lifting columns 24. The lifting column 24 is located directly below the organ chamber 1. The surgical instrument hanger 14 is a friction design that makes it less likely for the surgical instrument to fall off.
The display and support 27 is used to display an operating image or a software interface. The laparoscopic instrument access port 15 is a laparoscopic surgical instrument channel for manipulating and training the living organ 2 in the organ cartridge 1. The surgical instrument hanger 14 is used for hanging surgical instruments, and is convenient to operate. The lower part of the organ cabin 1 is provided with a lifting column 24 which can lift and lower an operation plane and is used for adapting to operators with different heights. The main machine cabin 18 is a multi-layer structure, and is used for accommodating and fixing active components such as a laparoscope main machine 19, a digestive endoscope main machine 21, a high-frequency electric knife 22, a cold light source 23 and the like. The lower part of the organ cabin 1 is provided with a lifting column 24 which can lift and lower an operation plane and is used for adapting to operators with different heights. The universal auxiliary support 32 is used for fixing a laparoscope hard mirror and the like, and is convenient for single-person operation.
Third embodiment-clinical preservation device
FIG. 13 shows a third embodiment of the present invention for clinical organ perfusion preservation. The basic principle follows the part described above with reference to fig. 1-5.
As shown in fig. 13, a plurality of living body organs 2 are stored in the organ container 1. The circulating liquid is pumped by the pump 3, firstly oxygenated by the oxygenator 11, secondly filtered by the filter plug 20 to remove impurities and air bubbles, and finally perfused to the organism organ 2 through the main pipeline 4-1 and the branch pipeline 4-2 under the drive of the pump 3. Wherein the tail end of the main pipeline 4-1 is divided into two or more branch pipelines 4-2, and the branch pipelines 4-2 form different flow rates according to different pipe diameters. The adjustable pipe clamp 5 is used for further accurately adjusting the pressure and the flow of the branch pipeline 4-2, the adjustable pipe clamp 5 is arranged on the branch pipeline 4-2 with a larger pipe diameter, the branch pipeline 4-2 is extruded to different degrees for flow limiting, the perfusion flow and the perfusion pressure of the branch pipeline 4-2 with the larger pipe diameter are directly reduced, and the flow and the pressure of the branch pipeline 4-2 with the smaller pipe diameter are improved. The temperature maintaining device 7 heats or cools the oxygenator 11 and the organ container 1 to maintain the temperatures of the organ 2 and the circulating liquid.
The above-described embodiments are merely preferred embodiments of the present invention, and general changes and substitutions by those skilled in the art within the technical scope of the present invention are included in the protection scope of the present invention.
Claims (13)
1. An ex vivo organ perfusion device, comprising:
an organ chamber (1) for accommodating an isolated organism organ (2);
a perfusion pipeline (4) which comprises a main pipeline (4-1) and branch pipelines (4-2) with different pipe diameters and perfuses the organism organ (2);
the adjustable pipe clamp (5) is arranged on the branch pipeline (4-2) and is used for adjusting the pressure and the flow;
a pump (3) which generates perfusion power for perfusing the living organ (2) through the perfusion line (4).
2. The organ ex vivo perfusion device of claim 1, further comprising:
the liquid storage bin (9) is used for storing circulating perfusate, and a micro-bubble generator (10) is arranged in the liquid storage bin (9) and used for generating oxygen micro-bubbles.
3. The organ ex vivo perfusion device of claim 1,
the tail end of the branch pipeline (4-2) is provided with a side hole (6).
4. The organ ex vivo perfusion device of claim 1, further comprising:
a temperature maintaining device (7) for maintaining the temperature of the living organ (2) and the circulating liquid;
the oxygenator (11) is arranged on the perfusion pipeline (4) and is used for continuously oxygenating the circulating perfusion liquid;
and the thrombus filter (20) is arranged on the perfusion pipeline (4) and is used for filtering impurities in the circulating perfusion liquid.
5. The organ ex vivo perfusion device of claim 1,
the organ bin (1) is internally provided with a filter screen (8) structure for filtering impurities.
6. The organ ex vivo perfusion device of claim 1,
the lower part of the organ bin (1) is a funnel-shaped or hemispherical drainage structure (25), so that when the organ bin rotates, the circulating perfusate is positioned at the lowest point of the organ bin (1).
7. The organ ex vivo perfusion device of claim 1,
the organ chamber (1) is provided with a laparoscope instrument inlet (15) and a digestive endoscope inlet (16), and the inside of the organ chamber (1) is provided with a lighting device (17), a disinfection system (30) and a diaphragm-imitating structure (28).
8. The organ ex vivo perfusion apparatus according to claim 1, wherein the organ cartridge (1) is laterally provided with a surgical instrument hanger (14) for hanging a surgical instrument.
9. The organ ex vivo perfusion device of claim 1, further comprising:
the operation plane, organ storehouse (1) are placed on the operation plane, and there is lift post (24) organ storehouse (1) below, can go up and down the operation plane, is provided with universal auxiliary stand (32) on the operation plane for fixed peritoneoscope hard mirror.
10. The organ ex vivo perfusion device of claim 1, further comprising:
the main machine cabin (18) is arranged below the organ cabin (1), and the main machine cabin (18) is of a multilayer structure and is used for accommodating the laparoscope main machine (19), the digestive endoscope main machine (21), the high-frequency electrotome (22) and the cold light source (23).
11. The organ ex vivo perfusion device of claim 1, further comprising:
the universal supporting structure (26) is positioned inside or below the organ bin (1) and can adjust the placing angle and position of the organ bin (1);
12. the organ ex vivo perfusion device of claim 1, further comprising:
and the negative plate (29) is positioned at the bottom of the organ bin (1) and provides a loop for the electric energy platform.
13. The organ ex vivo perfusion device of claim 1, further comprising:
a display and a stand (27) connected with the endoscope to display the operation image.
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| CN202111509615.3A CN113994954A (en) | 2021-12-10 | 2021-12-10 | Organ in-vitro perfusion device |
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| CN110459113A (en) * | 2019-03-22 | 2019-11-15 | 天一阁医疗科技(广州)有限公司 | A kind of organ perfusion's teaching and training system |
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| CN106659151A (en) * | 2014-06-02 | 2017-05-10 | 特兰斯迈迪茨公司 | Ex vivo organ care system |
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