CN113967325A - Physiotherapy equipment and preparation method thereof - Google Patents

Physiotherapy equipment and preparation method thereof Download PDF

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Publication number
CN113967325A
CN113967325A CN202111272844.8A CN202111272844A CN113967325A CN 113967325 A CN113967325 A CN 113967325A CN 202111272844 A CN202111272844 A CN 202111272844A CN 113967325 A CN113967325 A CN 113967325A
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China
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light
coating layer
emitting device
layer
light emitting
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Inventor
穆东华
董艳波
吴敬鹏
朱映光
胡永岚
谢静
赵杨
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Guan Yeolight Technology Co Ltd
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Guan Yeolight Technology Co Ltd
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Priority to CN202111272844.8A priority Critical patent/CN113967325A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0601Apparatus for use inside the body
    • A61N5/0603Apparatus for use inside the body for treatment of body cavities
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0601Apparatus for use inside the body
    • A61N5/0603Apparatus for use inside the body for treatment of body cavities
    • A61N2005/0606Mouth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0635Radiation therapy using light characterised by the body area to be irradiated
    • A61N2005/0643Applicators, probes irradiating specific body areas in close proximity
    • A61N2005/0649Applicators, probes irradiating specific body areas in close proximity using suction to fix the applicator to the tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0658Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0662Visible light
    • A61N2005/0663Coloured light

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

The present invention provides a physiotherapy apparatus and a method of manufacturing the physiotherapy apparatus, the physiotherapy apparatus comprising: a light emitting device; a clad layer for sealing the light emitting device; the adhesive layer is arranged on one side of the light-emitting surface of the light-emitting device on the coating layer and is made of a nano material, and the nano material is adhered to the coating layer at a preset inclination angle and is used for adhering the coating layer and tissues of the affected part of the oral cavity together. The light-emitting device can be sealed through the coating layer to isolate water and oxygen in the oral cavity environment, the coating layer is adhered to tissues of the oral cavity affected part through the nanometer material adhesive layer, so that the physiotherapy equipment can be conveniently adhered to the oral cavity affected part to treat oral ulcer by phototherapy, the problem of side effects caused by drug treatment in the prior art can be solved, and the problem of trouble caused to work generation of a patient due to treatment of handheld equipment in the prior art is solved. The physiotherapy equipment in this application simple structure, convenient to use.

Description

Physiotherapy equipment and preparation method thereof
Technical Field
The invention relates to the technical field of medical electronics, in particular to physiotherapy equipment and a preparation method of the physiotherapy equipment.
Background
The oral ulcer and the recurrent oral ulcer are common diseases which can not be recovered quickly, and have high recurrence rate, which causes inconvenience to the life of patients.
At present, the oral ulcer can be treated by medicines, and most commonly, the powdery medicines are smeared on an oral affected part to play the roles of resisting bacteria, diminishing inflammation and reducing swelling. However, for recurrent oral ulcer, patients frequently rely on drug therapy, and the phenomenon of frequent drug dosage can occur, thereby causing some side effects to the patients. In addition, laser treatment of canker sores is an option. For example, the portable medical equipment is adopted to treat the oral ulcer by irradiating laser (such as He-Ne laser), improve the skin microcirculation, promote the neogenesis of skin capillaries and the growth of fibroblasts and epithelia, thereby promoting the healing of skin mucous membrane and achieving the aim of eliminating the oral ulcer. However, due to the characteristic of recurrent oral ulcer, when the laser device is used for treatment, the affected part of the oral cavity needs to be irradiated by the handheld device of the patient, so that inconvenience is caused to normal work and life of the patient.
Disclosure of Invention
The embodiment of the invention provides physiotherapy equipment and a preparation method of the physiotherapy equipment, and aims to solve the problem that trouble is caused to work and life of a patient or side effects are caused when oral ulcer is treated at present.
In a first aspect, an embodiment of the present invention provides a physiotherapy apparatus, including:
a light emitting device;
a clad layer for sealing the light emitting device;
the bonding layer is arranged on the coating layer and on one side of the light-emitting surface of the light-emitting device, and is formed by a nano material which is adhered to the coating layer at a preset inclined angle and is used for bonding the coating layer and tissues of the affected part of the oral cavity together.
In a possible implementation manner, the bonding layer is prepared on the surface of the cladding layer by chemical vapor deposition under the action of a catalyst and a preset temperature;
the material of the catalyst comprises one or more of a metal material, an alloy material, a rare earth material or a high molecular polymer material;
the preset temperature is any value between 200 ℃ and 2000 ℃.
In one possible implementation, the adhesive layer is made of nanofiber materials distributed continuously or at intervals;
the nano-fiber material is composed of any one or combination of more than two of nano-rods, nano-wires and carbon nano-tubes.
In one possible implementation, the height of the nanofiber material is any value between 10nm and 100 um;
the diameter of the nanofiber material is any value between 10nm and 30 um.
In a possible implementation, the preset inclination angle is any value between 30 ° and 60 °.
In a possible implementation manner, the coating layer is made of a pocket-shaped material with an opening at one end, the light-emitting device is fixed in the coating layer by adopting a colloid material, and the opening end of the coating layer is bonded by adopting the colloid material;
the colloidal material comprises one of a DOPA-substituted polyethylene glycol polymer, fibrin glue and alkyl-alpha-cyanoacrylate glue;
the coating layer is made of any one of TPU, ethylene thermoplastic elastomer or soft PVC.
In one possible implementation, the light emitting device includes:
the light source comprises a plurality of light emitting areas which are distributed at different positions and have different sizes, and the light source comprises any one of an LED light source, an OLED light source, a miniLED light source and a microLED light source;
the thin film battery is connected with all the light emitting areas, arranged on the light source, deviates from the light emitting surface of the light emitting areas and is used for supplying power to all the light emitting areas;
the driving circuit board is connected with the thin film battery and is used for driving the thin film battery;
and the film switch is connected with the driving circuit board and used for turning on or off the driving circuit board through Bluetooth, NFC or a sensor to realize the subarea lighting of the light emitting area.
In a possible implementation manner, the substrate of the OLED light source is a flexible substrate, and the flexible substrate is made of any one of a TPU material, an ethylene thermoplastic elastomer material, or a soft PVC material;
and doping scattering particles on the flexible substrate to realize the effect of light extraction, wherein the scattering particles comprise titanium oxide or silicon oxide.
In a second aspect, an embodiment of the present invention provides a method for manufacturing a physiotherapy apparatus, including:
preparing a light-emitting device;
preparing a pocket-shaped coating layer with one open end;
fixing the light-emitting device in the cladding layer through an open end, and bonding the open end to seal the light-emitting device in the cladding layer;
preparing a nano material bonding layer on one side of the light-emitting surface of the light-emitting device on the coating layer, and adhering the nano material bonding layer to the coating layer at a preset inclination angle to obtain the physiotherapy equipment.
In one possible implementation manner, a nanomaterial adhesive layer is prepared on the coating layer on one side of the light-emitting surface of the light-emitting device, and the nanomaterial adhesive layer is adhered to the coating layer at a preset inclination angle, so as to obtain the physiotherapy apparatus, including:
on one side of the light-emitting surface of the light-emitting device on the coating layer, preparing a nanofiber material by taking a metal foil or a silicon wafer as a substrate and adopting a chemical vapor deposition mode under the action of a catalyst and high temperature, and growing the nanofiber material in an array mode at a preset inclination angle by adjusting the size and the inclination direction of holes in a mask plate to obtain a nanomaterial bonding layer; the mask plate is provided with holes, and the shape of the holes can be any one of circular, oval and polygonal; the diameter of the holes is any value between 10nm and 30um, and the height of the holes is any value between 10nm and 100 um; the angle of inclination of the holes is anywhere between 0 ° and 90 °, preferably anywhere between 30 ° and 60 °.
The embodiment of the invention provides physiotherapy equipment and a preparation method of the physiotherapy equipment. In addition, physiotherapy equipment simple structure in this application, convenient to use can solve the troublesome problem that adopts handheld device treatment to cause patient's life among the prior art.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings needed to be used in the embodiments or the prior art descriptions will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without inventive exercise.
Fig. 1 is a schematic view of a physiotherapy apparatus provided in an embodiment of the present invention;
FIG. 2 is a schematic diagram of a cladding layer provided by an embodiment of the present invention;
fig. 3 is a schematic view of a light-emitting device provided by an embodiment of the present invention;
fig. 4 is a schematic structural diagram of a light-emitting device according to an embodiment of the present invention;
fig. 5 is a schematic structural diagram of a light source in a light-emitting device provided in an embodiment of the invention;
FIG. 6 is a schematic view of an adhesive layer provided by an embodiment of the present invention;
fig. 7 is a flow chart illustrating a method for manufacturing a physiotherapy apparatus according to an embodiment of the present invention.
Detailed Description
In the following description, for purposes of explanation and not limitation, specific details are set forth, such as particular system structures, techniques, etc. in order to provide a thorough understanding of the embodiments of the invention. It will be apparent, however, to one skilled in the art that the present invention may be practiced in other embodiments that depart from these specific details. In other instances, detailed descriptions of well-known systems, devices, circuits, and methods are omitted so as not to obscure the description of the present invention with unnecessary detail.
In order to make the objects, technical solutions and advantages of the present invention more apparent, the following description is made by way of specific embodiments with reference to the accompanying drawings.
Fig. 1 is a schematic view of a physiotherapy apparatus provided in an embodiment of the present invention, which is detailed as follows: the physical therapy device may be a device for treating oral ulcers, comprising: a light emitting device 10, a cladding layer 20, and an adhesive layer 30.
The light-emitting device 10 is used for emitting light, and phototherapy is performed on the oral ulcer by using the light emitted by the light-emitting device 10 to improve skin microcirculation at an oral affected part, promote the regeneration of skin capillaries and the growth of fibroblasts and epithelia, so that the healing of skin mucous membranes is promoted; can also enhance phagocytic ability of phagocyte at oral cavity affected part, improve cellular immunity, increase cell permeability and enzyme activity, relieve inflammatory edema, and promote inflammatory cell dissipation, thereby achieving the purpose of eliminating oral ulcer.
Specifically, the color emitted by the light-emitting device 10 may be red, blue-green, or blue light, or a light source in which a plurality of colors are mixed:
the irradiation depth of the yellow green light with the wave band of 510 nm-590 nm is between the blue light and the red light, so that the dredging and the expansion of the capillary vessel in the skin depth can be promoted, the resistance of cells is enhanced, and the treatment effect of the affected part is accelerated.
Red light with a waveband of 590-810 nm can enable mitochondria to release cytochrome c oxidase, increase adenosine triphosphate, and enable cells to provide energy by utilizing the adenosine triphosphate, so that the metabolism of the cells is promoted; meanwhile, the red light irradiation heats molecules in the blood vessel, so as to adjust the blood vessel expansion and improve the blood circulation;
the blue light irradiation of the 440-510 nm wave band can be used for relieving pain and swelling caused by inflammation. Therefore, the present embodiment can achieve a plurality of different therapeutic effects by arranging different light sources.
And the coating layer 20 is used for sealing the light-emitting device 10 and completely isolating water and oxygen from entering, so that the light-emitting device 10 is completely isolated from the oral environment, and the biological safety performance of the physiotherapy equipment in the use process is improved.
The coating layer is made of a skin-friendly material, such as silica gel, Polydimethylsiloxane (PDMS), silica gel, Collagen (Collagen), Silicone Hydrogel (Silicone Hydrogel), Hydrogel (hydrocolloids), Polyurethane (PU), polymethyl methacrylate (PMMA), polymethylpentene polymer (PMP), Polyethylene (PE), polycarbonate, polystyrene, acrylonitrile butadiene styrene, polyolefin, polyamide, polyvinyl chloride, polyethylene, polypropylene, nylon, polyester, Silicone, polyimide, polytetrafluoroethylene, polyethersulfone, polysulfone, polyetheretherketone, chitosan, pectin, gelatin, nylon, fiber, and the like.
Preferably, the coating layer 20 is made of any one of TPU, ethylene thermoplastic elastomer, and soft PVC. The TPU material, the ethylene thermoplastic elastomer material or the soft PVC material have the advantages of no toxicity, water and oxygen barrier, skin friendliness, high elasticity, high elongation and the like, can be used in the oral cavity, and can realize the stretching characteristic of a light source.
The adhesive layer 30 is disposed on the coating layer at a side of the light emitting surface of the light emitting device, the adhesive layer 30 is formed of a nanomaterial, and the nanomaterial is adhered to the coating layer 20 at a predetermined inclined angle to adhere the coating layer 20 and tissues of the affected part of the oral cavity, so that the affected part of the oral cavity can be irradiated by light emitted from the light emitting device 10. The preset inclination angle between the nano material and the coating layer 20 is more than 0 degrees and less than 90 degrees, and preferably 30-60 degrees.
It should be noted that, when the nanomaterial is adhered to the tissue of the affected part of the oral cavity at a preset inclination angle of more than 30 ° and less than 60 °, a stronger van der waals force is formed between the adhesive layer 30 and the tissue of the affected part of the oral cavity, which can be adhered faster and stronger than the conventional adhesive, and further, the nanomaterial can be separated from the coating layer 20 by applying a force so that the inclination direction of the nanomaterial is the horizontal direction (i.e., the inclination angle is 0 °), which is more convenient to take down than the conventional adhesion method.
Above-mentioned physiotherapy equipment seals illuminator 10 through coating 20, water oxygen among the isolated oral cavity environment, bonding layer 30 organizes coating 20 and oral cavity affected part to bond together, through setting up the bonding angle between bonding layer 30 and coating 20, can make physiotherapy equipment glue in the oral cavity affected part more conveniently, simultaneously through utilizing the angle of inclination between bonding layer 30 and the oral cavity tissue, can make this physiotherapy equipment more conveniently take off after the wound is recovered. The physiotherapy equipment in this application simple structure, convenient to use can solve and adopt handheld device to treat among the prior art and cause troublesome problem to patient's life and work.
In some embodiments, the cover 20 is a pocket-shaped material with an open end, where the cover 20 is configured in the shape of a pocket, which facilitates sealing of the light emitting device 10, i.e., the light emitting device 10 is disposed in the cover and then only the open end is adhered.
The light emitting device 10 is fixed in the coating layer 20 by using a colloid material, and the open end of the coating layer 20 is bonded by using the colloid material, for example, the adopted colloid material may be a material having biocompatibility, and may be one of DOPA-substituted polyethylene glycol polymer, fibrin glue and alkyl-alpha-cyanoacrylate glue, for example. As shown in fig. 2, the coating layer 20 is in the shape of a pocket, the dotted line region can be a fixing region 201 of the light emitting device 10, and after the light emitting device 10 is fixed, the open end of the coating layer 20 can be bonded to ensure that the coating layer has excellent sealing performance, so that water and oxygen can be completely isolated from entering, and the physical safety of the physiotherapy equipment can be improved.
Here, the open end of the cover 20 may be on the upper or lower side, and the position of the open end is not particularly limited in this embodiment as long as the cover 20 is provided with an open end in which the light emitting device 10 can be placed, and after the light emitting device 10 is fixed, the open end is bonded.
In some embodiments, as shown in fig. 3, the light emitting device 10 may include: a light source 101, a thin film battery 102, a driving circuit board 103 and a thin film switch 104.
The light source 101 may include a plurality of light emitting areas 1011 distributed at different positions and having different sizes, as shown in fig. 4, and the light source may be one of an OLED light source, an LED light source, a miniLED light source, and a micro LED light source.
As shown in fig. 3, the thin film battery 102 is disposed on the light source 101, and is far away from the light emitting surface of the light source 101, and is connected to all the light emitting areas for supplying power to all the light emitting areas. The thin film battery 102 has the characteristics of being light, thin and bendable, so that the light-emitting device is lighter and thinner, foreign body sensation is reduced in the oral cavity, and the experience of a patient is improved.
And the driving circuit board 103 is connected with the thin film battery 102 and is used for providing driving for the thin film battery 102, so that the thin film battery 102 supplies power to all the light emitting regions.
The membrane switch 104 is connected to the driving circuit board 103, and is used for turning on or off the driving circuit board 103 through bluetooth, NFC or a sensor, so as to realize the partition lighting of the light-emitting area. The zonal lighting can realize accurate treatment on the oral ulcer so as to avoid damaging healthy oral tissues.
Preferably, as shown in fig. 5, the light source 101 is an OLED light source, in this embodiment, the substrate of the OLED light source is a flexible substrate, for example, the flexible substrate may be made of rubber, PMDS, PTFE, fibroin, or the like, and more preferably, the flexible substrate is made of a material consistent with the material of the coating layer, that is, any one of a TPU material, a vinyl thermoplastic elastomer material, or a soft PVC material. Adopt any kind in TPU material, ethylene class thermoplastic elastomer material or the soft PVC material as the light source basement, because TPU material, ethylene class thermoplastic elastomer material or soft PVC material have nontoxic characteristic, separation water oxygen, parent's skin, elasticity are high, advantage such as elongation is big, not only can realize that this physiotherapy device has certain tensile characteristic, can reduce process flow with coating integrated into one piece moreover.
The flexible substrate may be further doped with scattering particles to achieve light extraction, and the scattering particles include titanium oxide or silicon oxide.
As shown in fig. 5, the light source 101 may further include a first electrode layer 502, a hole transport layer 503, a light emitting layer 504, an electron transport layer 505, a second electrode 506, and an encapsulating layer 507 in this order, in addition to the flexible base layer 501, wherein the encapsulating layer 507 encapsulates the first electrode layer 502, the hole transport layer 503, the light emitting layer 504, the electron transport layer 505, and the second electrode 506, and the encapsulating layer 507 has a thin film encapsulation structure, and is preferably made of a material that is identical to a material of the cladding layer, that is, any one of a TPU material, an ethylene thermoplastic elastomer material, and a soft PVC material.
In some embodiments, the adhesion layer 30 disposed on the surface of the cladding layer 20 can be prepared by chemical vapor deposition under the action of a catalyst and a predetermined temperature.
The material of the catalyst can be one or more of metal material, alloy material, rare earth material or high molecular polymer material. Wherein, the metal material can be one or more of Fe, Co, Ni or Cu. The high molecular polymer material can be one or more of thiophene, porphyrin and polyaniline.
The preset temperature is any one of 200 ℃ to 2000 ℃. The preset temperature corresponding to different catalyst materials is within a certain range of 200 ℃ to 2000 ℃. For example, when the catalyst is Fe, the predetermined temperature may be any value within a range of 500 ℃ to 1000 ℃; when the catalyst is Cu, the predetermined temperature may be any value within a range of 300 ℃ to 500 ℃.
Alternatively, the bonding material 30 is formed of a continuous or spaced nanofiber material. The nanofiber material comprises any one of nanorods, nanowires and carbon nanotubes or a combination of at least two of the nanorods, the nanowires and the carbon nanotubes. The height of the nanofiber material is any value between 10nm and 100 um; the diameter of the nanofiber material is anywhere between 10nm to 30 um.
Optionally, the preparation method of the adhesive layer 30 includes: the nanofiber material 601 is prepared by taking a metal foil or a silicon wafer as a substrate and adopting a chemical vapor deposition mode under the action of a catalyst and high temperature, the nanofiber material 601 grows in an array mode at a preset inclination angle by adjusting the size of holes on a mask plate and the inclination direction of the holes, and a nanomaterial bonding layer is obtained, as shown in a schematic diagram of the bonding layer shown in fig. 6. Optionally, the mask plate is provided with a hole, and the shape of the hole may be any one of a circle, an ellipse and a polygon. The diameter of the holes is anywhere between 10nm to 30 um. The height of the holes is any value between 10nm and 100 um; the angle of inclination of the holes is anywhere between 0 ° and 90 °, preferably anywhere between 30 ° and 60 °.
When the adhesive layer 30 is adhered to the tissues of the affected part of the oral cavity at an inclination angle which is greater than 30 degrees and less than 60 degrees, stronger van der waals force can be formed between the adhesive layer 30 and the tissues of the affected part of the oral cavity, and the adhesive layer can be adhered more quickly and more strongly than the conventional adhesive, further, the nanomaterial can be separated from the coating layer 20 by applying force to ensure that the inclination direction of the nanomaterial is the horizontal direction (namely, the inclination angle is 0 degree), and compared with the conventional adhesion mode, the adhesive layer can be taken down more conveniently.
When the nanomaterial adhesive layer is made of a material having a certain conductive property, such as carbon nanotubes, a path is formed when the nanomaterial is in contact with the oral cavity, and the light is fed back to the driving circuit board 103 by providing a lead, so that the light source 101 in the contact area between the nanomaterial and the oral cavity can be controlled to emit light. The light source 101 can be designed into a surface light source capable of being controlled in a partition mode, the membrane switch 102 serves as a touch switch, when the membrane switch is attached and contacted, the switch is triggered, the contacted area can emit light, the non-bonded area is not bright, and therefore accurate treatment is achieved. In addition, as shown in fig. 4, the light source 101 of the physiotherapy apparatus may include a plurality of light emitting regions 1011, each of which is different in position and size, and each of which is provided as a plurality of surface light sources that can be individually controlled, and precise treatment is achieved by independently controlling light emission of one or more surface light sources.
Above-mentioned physiotherapy equipment seals illuminator through the coating, and water oxygen among the isolated oral cavity environment, the reliability is high, and the bond line is in the same place coating and the tissue bonding of oral cavity affected part for physiotherapy equipment can conveniently glue in the oral cavity affected part or other affected parts that can adopt phototherapy treatment, adopts phototherapy treatment oral ulcer or other wounds, thereby can solve the side effect problem that adopts the drug therapy to bring among the prior art. In addition, the nano material is adhered to the tissues of the affected part of the oral cavity at the preset inclination angle in the embodiment of the invention, so that the physiotherapy equipment can be more conveniently adhered to the affected part of the oral cavity with stronger Van der Waals force, meanwhile, the nano material can be separated from the oral cavity by forming the nano material and the tissues of the oral cavity into a horizontal direction, and the physiotherapy equipment can be conveniently taken down, thereby solving the problem that the work generation of a patient is troublesome due to the adoption of handheld equipment for treatment in the prior art. The utility model provides a physiotherapy equipment attaches illuminator by the cladding, sets up the bond line on the cladding again for physiotherapy equipment simple structure.
As shown in fig. 7, the embodiment of the present invention further provides a method for manufacturing a physiotherapy apparatus, which is described in detail below.
Step 701, preparing a light-emitting device;
referring to fig. 1, a light emitting device 10 for emitting light, wherein the light emitted from the light emitting device 10 is used for phototherapy for treating the oral ulcer to improve skin microcirculation at the affected part of the oral cavity, promote the neogenesis of skin capillaries, and the growth of fibroblasts and epithelia, thereby promoting the healing of skin mucosa; can also enhance phagocytic ability of phagocyte at oral cavity affected part, improve cellular immunity, increase cell permeability and enzyme activity, relieve inflammatory edema, and promote inflammatory cell dissipation, thereby achieving the purpose of eliminating oral ulcer.
Specifically, the color emitted by the light-emitting device 10 may be red, blue-green, or blue light, or a light source in which a plurality of colors are mixed:
the irradiation depth of the yellow green light with the wave band of 510 nm-590 nm is between the blue light and the red light, so that the dredging and the expansion of the capillary vessel in the skin depth can be promoted, the resistance of cells is enhanced, and the treatment effect of the affected part is accelerated.
Red light with a waveband of 590-810 nm can enable mitochondria to release cytochrome c oxidase, increase adenosine triphosphate, and enable cells to provide energy by utilizing the adenosine triphosphate, so that the metabolism of the cells is promoted; meanwhile, the red light irradiation heats molecules in the blood vessel, so as to adjust the blood vessel expansion and improve the blood circulation;
the blue light irradiation of the 440-510 nm wave band can be used for relieving pain and swelling caused by inflammation. Therefore, the present embodiment can achieve a plurality of different therapeutic effects by arranging different light sources.
Alternatively, referring to fig. 3, the light emitting device 10 may include: a light source 101, a thin film battery 102, a driving circuit board 103 and a thin film switch 104.
In the preparation of the light emitting device, first, the light source 101 including a plurality of light emitting regions 1011 having different sizes distributed at different positions is prepared;
the backlight surface of the light source 101 is arranged on the thin film battery 102, and all light emitting areas of the light source 101 are connected with the thin film battery 102; the thin film battery 102 is used to supply power to all light emitting regions.
Connecting the thin film battery 102 with a driving circuit board 103, wherein the driving circuit board 103 is used for providing driving for the thin film battery 102, so that the thin film battery 102 supplies power for all light-emitting regions;
the driving circuit board 103 is connected with the membrane switch 104, and the membrane switch 104 is used for turning on or off the driving circuit board 103 through bluetooth, NFC or a sensor, so as to realize the subarea lighting of the light-emitting area. The zonal lighting can realize accurate treatment on the oral ulcer so as to avoid damaging healthy oral tissues.
Optionally, the light source may be one of an OLED light source, an LED light source, a miniLED light source, and a micro LED light source. As shown in fig. 5, the light source 101 is preferably an OLED light source, in this embodiment, the substrate of the OLED light source is a flexible substrate, for example, the flexible substrate may be made of rubber, PMDS, PTFE, fibroin, or the like, and more preferably made of a material consistent with the material of the coating layer, that is, any one of a TPU material, a vinyl thermoplastic elastomer material, or a soft PVC material. Adopt any kind in TPU material, ethylene class thermoplastic elastomer material or the soft PVC material as the light source basement, because TPU material, ethylene class thermoplastic elastomer material or soft PVC material have nontoxic characteristic, separation water oxygen, parent's skin, elasticity are high, advantage such as elongation is big, not only can realize that this physiotherapy device has certain tensile characteristic, can reduce process flow with coating integrated into one piece moreover.
The thin film battery 102 has the characteristics of being light, thin and bendable, so that the light-emitting device is lighter and thinner, foreign body sensation is reduced in the oral cavity, and the experience of a patient is improved.
Step 702, a pocket-shaped cover layer with an opening at one end is prepared.
Referring to fig. 2, the covering layer 20 is formed in a pocket shape, and the dotted area may be a fixing area 201 of the light emitting device 10, so that the light emitting device 10 can be conveniently sealed, i.e., only one end of the opening is needed to be bonded after the light emitting device 10 is disposed in the covering layer. Here, the open end of the cover 20 may be on the upper or lower side, and the position of the open end is not particularly limited in this embodiment as long as an open end, in which the light emitting device 10 can be placed, is provided on the cover 20.
The coating layer is made of a skin-friendly material, such as silica gel, Polydimethylsiloxane (PDMS), silica gel, Collagen (Collagen), Silicone Hydrogel (Silicone Hydrogel), Hydrogel (hydrocolloids), Polyurethane (PU), polymethyl methacrylate (PMMA), polymethylpentene polymer (PMP), Polyethylene (PE), polycarbonate, polystyrene, acrylonitrile butadiene styrene, polyolefin, polyamide, polyvinyl chloride, polyethylene, polypropylene, nylon, polyester, Silicone, polyimide, polytetrafluoroethylene, polyethersulfone, polysulfone, polyetheretherketone, chitosan, pectin, gelatin, nylon, fiber, and the like.
Preferably, the coating layer 20 is made of any one of TPU, ethylene thermoplastic elastomer, and soft PVC. The TPU material, the ethylene thermoplastic elastomer material or the soft PVC material have the advantages of no toxicity, water and oxygen barrier, skin friendliness, high elasticity, high elongation and the like, can be used in the oral cavity, and can realize the stretching characteristic of a light source.
Step 703, fixing the light emitting device in the cladding layer through the open end, and bonding the open end to seal the light emitting device in the cladding layer.
Referring to fig. 2, the coating layer 20 is in the shape of a pocket, and after the light emitting device 10 is fixed in the dotted line region, the open end of the coating layer 20 can be bonded to ensure that the coating layer has excellent sealing performance, can completely isolate water and oxygen from entering, and improve the physical safety of the physical therapy device.
Optionally, the light emitting device 10 is fixed in the covering layer 20 by using a colloid material, and the open end of the covering layer 20 is also bonded by using the colloid material, for example, the adopted colloid material may be a material having biocompatibility, and may be one of DOPA-substituted polyethylene glycol polymer, fibrin glue and alkyl- α -cyanoacrylate glue, for example.
Step 704, preparing a nano material adhesive layer on the coating layer on one side of the light-emitting surface of the light-emitting device, and adhering the nano material adhesive layer on the coating layer at a preset inclination angle to obtain the physiotherapy equipment.
The adhesive layer is used for combining and bonding the coating layer and the affected part of the oral cavity, and can be prepared by chemical vapor deposition under the action of a catalyst and a preset temperature.
The material of the catalyst can be one or more of metal material, alloy material, rare earth material or high molecular polymer material. Wherein, the metal material can be one or more of Fe, Co, Ni or Cu. The high molecular polymer material can be one or more of thiophene, porphyrin and polyaniline.
The preset temperature is any one of 200 ℃ to 2000 ℃. The preset temperature corresponding to different catalyst materials is within a certain range of 200 ℃ to 2000 ℃. For example, when the catalyst is Fe, the predetermined temperature may be any value within a range of 500 ℃ to 1000 ℃; when the catalyst is Cu, the predetermined temperature may be any value within a range of 300 ℃ to 500 ℃.
The manner of preparing the adhesive layer on the clad layer is as follows: the preparation method comprises the steps of taking a metal foil or a silicon wafer as a substrate, preparing the nanofiber material 601 under the action of a catalyst and high temperature in a chemical vapor deposition mode, and enabling the nanofiber material 601 to grow in an array mode at a preset inclination angle by adjusting the size of holes in a mask plate and the inclination direction of the holes to obtain a nanomaterial bonding layer. The diameter of the holes is anywhere between 10nm to 30 um. The height of the holes is any value between 10nm and 100 um; the angle of inclination of the holes is anywhere between 0 ° and 90 °, preferably anywhere between 30 ° and 60 °.
When the nanomaterial adhesive layer 30 is adhered to the tissues of the affected part of the oral cavity at a preset inclination angle of more than 30 degrees and less than 60 degrees, stronger van der waals force can be formed between the adhesive layer 30 and the tissues of the affected part of the oral cavity, and the adhesion can be faster and stronger than that of a traditional adhesive, further, the adhesion layer 30 can be separated from the coating layer 20 by applying force to enable the inclination direction of the carbon nanotubes to be the horizontal direction (namely, the inclination angle is 0 degree), and compared with the traditional adhesion mode, the nanomaterial adhesive layer 30 can be taken down more conveniently.
According to the preparation method of the physiotherapy equipment, the light-emitting device and the pocket-shaped coating layer with the opening at one end are respectively prepared, the light-emitting device is fixed in the coating layer through the opening end and is bonded with the opening end, the light-emitting device is sealed in the coating layer, the bonding layer is prepared on one side of the light-emitting surface of the light-emitting device on the coating layer, and the preset inclination angle is formed between the bonding layer and the coating layer, so that the obtained physiotherapy equipment is simple in preparation operation and high in efficiency. In addition, the coating layer seals the light-emitting device to isolate water and oxygen in the oral cavity environment, and the reliability is high. The nanomaterial can be bonded with the tissues of the affected part of the oral cavity with stronger bonding force by presetting an inclination angle, and the physiotherapy equipment can be taken down more conveniently by forming the nanomaterial and the tissues of the oral cavity into a horizontal direction, so that the convenience and quickness in treatment can be provided for a patient.
The above-mentioned embodiments are only used for illustrating the technical solutions of the present invention, and not for limiting the same; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; such modifications and substitutions do not substantially depart from the spirit and scope of the embodiments of the present invention, and are intended to be included within the scope of the present invention.

Claims (10)

1. A physiotherapy apparatus, comprising:
a light emitting device;
a clad layer for sealing the light emitting device;
the bonding layer is arranged on the coating layer and on one side of the light-emitting surface of the light-emitting device, and is formed by a nano material which is adhered to the coating layer at a preset inclined angle and is used for bonding the coating layer and tissues of the affected part of the oral cavity together.
2. The physiotherapy apparatus according to claim 1, wherein the adhesive layer is disposed on the surface of the cladding layer and prepared by chemical vapor deposition under the action of a catalyst and a preset temperature;
the material of the catalyst comprises one or more of a metal material, an alloy material, a rare earth material or a high molecular polymer material;
the preset temperature is any value between 200 ℃ and 2000 ℃.
3. The physical therapy device according to claim 1, wherein said adhesive layer is made of a nanofiber material distributed continuously or at intervals;
the nano-fiber material is composed of any one or combination of more than two of nano-rods, nano-wires and carbon nano-tubes.
4. The physiotherapy apparatus of claim 3, wherein the nanofiber material has a height of any value between 10nm and 100 um;
the diameter of the nanofiber material is any value between 10nm and 30 um.
5. The physiotherapy apparatus of claim 1, wherein the preset inclination angle is any value between 30 ° and 60 °.
6. The physiotherapy apparatus according to any one of claims 1 to 5, wherein the coating layer is a pocket-shaped material with an open end, the light emitting device is fixed in the coating layer by using a colloid material, and the open end of the coating layer is bonded by using the colloid material;
the colloidal material comprises one of a DOPA-substituted polyethylene glycol polymer, fibrin glue and alkyl-alpha-cyanoacrylate glue;
the coating layer is made of any one of TPU, ethylene thermoplastic elastomer or soft PVC.
7. The physiotherapy apparatus according to any one of claims 1 to 5, wherein the light emitting device comprises:
the light source comprises a plurality of light emitting areas which are distributed at different positions and have different sizes, and the light source comprises any one of an LED light source, an OLED light source, a miniLED light source and a microLED light source;
the thin film battery is connected with all the light emitting areas, arranged on the light source, deviates from the light emitting surface of the light emitting areas and is used for supplying power to all the light emitting areas;
the driving circuit board is connected with the thin film battery and is used for driving the thin film battery;
and the film switch is connected with the driving circuit board and used for turning on or off the driving circuit board through Bluetooth, NFC or a sensor to realize the subarea lighting of the light emitting area.
8. The physiotherapy apparatus of claim 7, wherein the substrate of the OLED light source is a flexible substrate, and the flexible substrate is made of any one of TPU, ethylene thermoplastic elastomer or soft PVC;
and doping scattering particles on the flexible substrate to realize the effect of light extraction, wherein the scattering particles comprise titanium oxide or silicon oxide.
9. A method of manufacturing a physical therapy device, comprising:
preparing a light-emitting device;
preparing a pocket-shaped coating layer with one open end;
fixing the light-emitting device in the cladding layer through an open end, and bonding the open end to seal the light-emitting device in the cladding layer;
preparing a nano material bonding layer on one side of the light-emitting surface of the light-emitting device on the coating layer, and adhering the nano material bonding layer on the coating layer at a preset inclination angle to obtain the physiotherapy equipment.
10. The method of claim 9, wherein a nanomaterial adhesive layer is formed on the coating layer on a side of the light emitting surface of the light emitting device, and the nanomaterial adhesive layer is adhered to the coating layer at a predetermined inclination angle, so as to obtain the physiotherapy apparatus, comprising:
on one side of the light-emitting surface of the light-emitting device on the coating layer, preparing a nanofiber material by taking a metal foil or a silicon wafer as a substrate and adopting a chemical vapor deposition mode under the action of a catalyst and high temperature, and growing the nanofiber material in an array mode at a preset inclination angle by adjusting the size and the inclination direction of holes in a mask plate to obtain a nanomaterial bonding layer; the mask plate is provided with holes, and the shape of the holes can be any one of circular, oval and polygonal; the diameter of the holes is any value between 10nm and 30um, and the height of the holes is any value between 10nm and 100 um; the angle of inclination of the holes is anywhere between 0 ° and 90 °, preferably anywhere between 30 ° and 60 °.
CN202111272844.8A 2021-10-29 2021-10-29 Physiotherapy equipment and preparation method thereof Pending CN113967325A (en)

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