CN113951833A - Channel pluggable portable near-infrared brain function imaging system and method - Google Patents
Channel pluggable portable near-infrared brain function imaging system and method Download PDFInfo
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Abstract
The invention discloses a channel pluggable portable near-infrared brain function imaging system and a channel pluggable portable near-infrared brain function imaging method, wherein the system comprises a control assembly, wherein the control assembly is respectively in signal transmission with at least one transmitting probe and at least one receiving probe in an electric signal mode; at least one emission probe is provided with a first pluggable interface and is used for being electrically connected with the control assembly through the first pluggable interface and receiving the driving carrier wave sent by the control assembly; at least one receiving probe is provided with a second pluggable interface and is used for being electrically connected with the control assembly through the second pluggable interface and sending a feedback signal to the control assembly; the control assembly is provided with a multi-channel acquisition module for sampling a feedback signal of a specified channel, and the sampling frequency of the multi-channel acquisition module is the same as the frequency of the driving carrier wave. The invention is used for realizing the pluggable detection channel and the free combination of the channels.
Description
Technical Field
The invention belongs to the technical field of medical imaging, and particularly relates to a channel pluggable portable near-infrared brain function imaging system and a channel pluggable portable near-infrared brain function imaging method.
Background
With the increase of application scenes of the near-infrared brain function imaging system, the near-infrared brain function imaging system needs to adapt to more research scenes, and the plugging and unplugging of the channel and the free combination of the channel become very important requirements.
The existing near-infrared brain function imaging mostly adopts optical fiber signal connection, transmits laser to a transmitting probe through a transmitting optical fiber and irradiates the laser on the head of a human body, for example, China with a publication number of CN110786843A is specially favorable for a noninvasive optical measurement method disclosed in 2020, 2, month and 14 days, and the near-infrared measurement equipment comprises a laser which is connected with the transmitting probe through the transmitting optical fiber; the photoelectric detector is connected to the receiving probe through a receiving optical fiber; the output of the photodetector is connected to a correlator via a cable, which is connected to a computer. The signal transmission in the method is easily interfered by external optical signals and environmental signals, so that the error of monitoring data is larger.
Due to the sensitivity of the optical fiber transmission to external signals, the connection between the optical fiber and the probe is very firm and tight, the optical fiber is not easy to be plugged, and the plugging and unplugging of the optical fiber transmission line also have the problems of light leakage and the like, so that signal interference is caused, and the test precision is influenced.
Therefore, it is desirable to provide a near-infrared brain function imaging system, which has the characteristics that the channels can be plugged and unplugged and can be freely combined on the premise of not affecting the detection precision.
Disclosure of Invention
In order to overcome the defects of the prior art, the invention provides a channel pluggable portable near-infrared brain function imaging system and a channel pluggable portable near-infrared brain function imaging method, which are used for realizing pluggable detection channels and free combination of the channels.
According to an aspect of the present specification, there is provided a portable near-infrared brain function imaging system with a pluggable channel, comprising a control component, which is in signal transmission with at least one transmitting probe and at least one receiving probe respectively in an electrical signal manner; at least one emission probe is provided with a first pluggable interface and is used for being electrically connected with the control assembly through the first pluggable interface and receiving the driving carrier wave sent by the control assembly; at least one receiving probe is provided with a second pluggable interface and is used for being electrically connected with the control assembly through the second pluggable interface and sending a feedback signal to the control assembly; the control assembly is provided with a multi-channel acquisition module for sampling a feedback signal of a specified channel, and the sampling frequency of the multi-channel acquisition module is the same as the frequency of the driving carrier wave.
Among the above-mentioned technical scheme, the mode through the signal of telecommunication transmits between control assembly and transmitting probe and the receiving probe, and realize being connected or breaking off of control assembly and transmitting probe through first pluggable interface, realize being connected or breaking off of control assembly and receiving probe through second pluggable interface, because the relation of electricity connection, the circuit is with first, the connection or the breaking off of second pluggable interface is very easy, and the connection or the breaking off of arbitrary passageway can not exert an influence to other passageways, interference signal does not produce, thereby when realizing that the passageway can be unplugged and plugged, the accuracy of detecting the signal has been guaranteed.
As a further technical solution, the control component is connected to a management terminal, and is configured to determine an available channel according to a channel selection instruction sent by the management terminal, and extract a feedback signal transmitted by the available channel. According to the technical scheme, different detection channels can be conveniently selected according to different research scenes, the available channels are determined in a mode that the terminal sends instructions, then only signals of the available channels are collected and extracted in operation, free combination of different channels in different application scenes is achieved, cost is low, and operation is simple.
According to the technical scheme, the channels can be freely selected, the interested channel is appointed, and the multi-channel acquisition module is controlled to sample the signal in the interested channel in an appointed time period; or, the uninteresting channels are designated, and the multichannel acquisition module is controlled not to sample the uninteresting channels in the designated time period. The technical scheme realizes free combination of channels, greatly expands application scenes of near-infrared brain function imaging, and does not need to additionally increase cost.
As a further technical solution, the management terminal includes a hardware terminal or a software application. The technical scheme does not limit the form of the terminal for providing the channel selection instruction, and the terminal can be driven by hardware or software programs as long as the instruction can be transmitted, so that the applicability of the whole system is improved.
As a further technical scheme, the driving carrier is a high-frequency carrier with fixed frequency, and the high-frequency carrier is transmitted to the emission probe in an electric signal manner and is used for driving the LED patch in the emission probe to emit light. The driving carrier is set to be the carrier with fixed frequency, and the purpose is to be convenient for sampling with the AD sampling frequency which is the same with the driving carrier when carrying out multi-channel signal acquisition, thereby completing the extraction and restoration of the original cerebral blood flow signal while sampling the signal, needing no special signal demodulation chip to be configured, and reducing the whole system cost. The driving carrier is set to be a high-frequency carrier, and the purpose of the system is to achieve the near-infrared brain function imaging system of signal acquisition in a time-sharing mode, as long as the sampling frequency is high enough, the monitoring of human physiological signals is not affected in the process, and the restoration degree of original brain blood flow signals is guaranteed.
As a further technical solution, the feedback signal is a modulated wave signal modulated by a driving carrier. During multi-channel acquisition, the modulation wave signal is sampled through the AD sampling signal with the same frequency as the driving carrier, the original cerebral blood flow signal is extracted and restored while the signal is sampled, and the restoration degree of the extracted signal can be ensured.
As a further technical scheme, an LED driving circuit and an LED patch are integrated in the transmitting probe. According to the technical scheme, the LED driving circuit is integrated in the transmitting probe, so that the space at the tail of the transmitting probe is fully utilized, the size of the control assembly is reduced, and the portability of the whole system is improved.
As a further technical solution, a photoelectric conversion circuit and a signal processing circuit are integrated in the receiving probe. The light signal scattered by the brain skin is converted into an electric signal through the photoelectric conversion circuit, the electric signal is amplified and filtered through the signal processing circuit, and then the electric signal is transmitted to the control assembly.
According to an aspect of the present specification, there is provided a channel pluggable portable near-infrared brain function imaging method, implemented by using the system, the method including:
sending a driving carrier wave to drive a transmitting probe to emit probe light;
the receiving probe collects a feedback signal based on the detection light;
and receiving a feedback signal, and sampling the feedback signal in the specified channel, wherein the sampling frequency is the same as the frequency of the driving carrier wave.
In the technical scheme, the driving carrier is sent in an electric signal mode at first, the driving transmitting probe is driven to transmit an optical signal and irradiate the optical signal to the brain skin, then the receiving probe receives a feedback optical signal generated by the brain skin scattering and processes the feedback optical signal, and the feedback optical signal is transmitted to the control assembly in an electric signal mode, the control assembly collects and extracts the signal in the preselected appointed channel, and the collection frequency is consistent with the frequency of the driving carrier, so that the original brain blood flow signal can be extracted and restored while the signal is collected, the restoration and extraction of the signal can be realized without a special signal demodulation chip, and the extracted brain blood flow signal has higher restoration degree.
As a further technical solution, the method further comprises: and acquiring a channel selection instruction, determining an available channel, and extracting a feedback signal transmitted by the available channel. The channel selection instruction can be selected according to a specific research scene, unnecessary channels are closed, only the required channels are utilized, free combination of the channels is achieved, meanwhile, the working efficiency is improved, and the application scene is expanded through low cost and simple operation.
As a further technical solution, for an unavailable channel, a feedback signal input via the unavailable channel is not sampled for a preset period.
Compared with the prior art, the invention has the beneficial effects that:
(1) the control assembly is electrically connected with the transmitting probe and the receiving probe and transmits the signals in an electric signal mode, and the control assembly is connected with the lines between the transmitting probe and the receiving probe and realizes the pluggable connection through the first pluggable interface and the second pluggable interface; due to the electrical connection relationship, the connection or disconnection of the line and the first and second plug-in interfaces is very easy, the connection or disconnection of any channel can not affect other channels, interference signals are not generated, and the accuracy of detection signals is ensured while the channels can be plugged.
(2) The control assembly is connected with the transmitting probe and the receiving probe through the lines in a pluggable relationship, so that the control assembly can be disconnected from the transmitting probe and the receiving probe when not in use, the control assembly can be stored or carried separately, and the portable function of the whole system is realized.
(3) The invention can freely select channels, appoint interested channels and control the multi-channel acquisition module to sample signals in the interested channels at appointed time; or, the uninteresting channels are designated, and the multichannel acquisition module is controlled not to sample the uninteresting channels in the designated time period, so that the free combination of the channels is realized, the application scene of the near-infrared brain function imaging is greatly expanded, and the additional cost is not required to be increased.
Drawings
FIG. 1 is a schematic diagram of a portable near-infrared brain function imaging system with pluggable channels according to an embodiment of the present invention;
FIG. 2 is a schematic diagram of a portable near-infrared brain function imaging system with pluggable channels according to another embodiment of the present invention
FIG. 3 is a schematic diagram of a transmission probe according to an embodiment of the present invention.
FIG. 4 is a schematic diagram of a receiving probe according to an embodiment of the present invention.
FIG. 5 is a flow chart of a method according to an embodiment of the present invention.
Detailed Description
The technical solutions of the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings, and it is to be understood that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments of the present invention without any inventive step, are within the scope of the present invention.
In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; may be mechanically connected, may be electrically connected or may be in communication with each other; either directly or indirectly through intervening media, either internally or in any other relationship. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.
Example 1
The present embodiment provides a portable near-infrared brain function imaging system with a pluggable channel, as shown in fig. 1, which includes a control component, a transmitting probe and a receiving probe. The control assembly is electrically connected with the transmitting probe and the receiving probe.
The control assembly can be realized by adopting a control panel or equipment with the functions of sending control signals, receiving detection signals and carrying out multi-channel acquisition, and the adopted equipment also has the function of displaying.
The control assembly is provided with a multi-channel acquisition module for sampling a feedback signal of a specified channel, and the AD sampling frequency of the multi-channel acquisition module is the same as the frequency of the driving carrier wave.
The transmitting probe is provided with a first pluggable interface and is used for being electrically connected with the control assembly through the first pluggable interface and receiving the driving carrier wave sent by the control assembly.
The driving carrier is a high-frequency carrier with fixed frequency, on one hand, the multi-channel signal acquisition can be conveniently carried out at the AD sampling frequency which is the same as the frequency of the driving carrier, so that the original cerebral blood flow signal is extracted and restored while the signal is sampled, and a special signal demodulation chip is not required to be configured; on the other hand, for the near-infrared brain function imaging system for realizing signal acquisition in a time-sharing manner, as long as the sampling frequency is high enough, the monitoring of the physiological signals of the human body is not influenced in the process, and the reduction degree of the original brain blood flow signals is ensured.
The receiving probe is provided with a second pluggable interface and is used for being electrically connected with the control assembly through the second pluggable interface and sending a feedback signal to the control assembly.
The feedback signal is a modulated wave signal modulated by a driving carrier. During multi-channel acquisition, the modulation wave signal is sampled through the AD sampling signal with the same frequency as the driving carrier, the original cerebral blood flow signal is extracted and restored while the signal is sampled, and the restoration degree of the extracted signal can be ensured.
In this embodiment, the control assembly transmits with the mode of the signal of telecommunication between transmitting probe and the receiving probe, and realize being connected or breaking off of control assembly and transmitting probe through first pluggable interface, realize being connected or breaking off of control assembly and receiving probe through second pluggable interface, because the relation of electricity connection, the circuit is very easy with first, the connection or the breaking off of second pluggable interface, and the connection or the breaking off of arbitrary passageway can not exert an influence to other passageways, do not produce interfering signal, thereby when realizing that the passageway can be plugged, the accuracy of detecting signal has been guaranteed.
Example 2
As shown in fig. 2, different from embodiment 1, the control component of this embodiment is connected to a management terminal, and is configured to determine an available channel according to a channel selection instruction sent by the management terminal, and extract a feedback signal transmitted by the available channel. According to the method, different detection channels are selected according to different research scenes, the available channels are determined in a mode that the terminal sends instructions, and then only signals of the available channels are collected and extracted in operation, so that free combination of different channels in different application scenes is achieved.
The management terminal comprises a hardware terminal or a software application program. The embodiment does not limit the form of the terminal for providing the channel selection instruction, and the terminal can be driven by hardware or software programs as long as the instruction can be transmitted, so that the applicability of the whole system is improved.
The embodiment can freely select the channel, appoint the interested channel and control the multi-channel acquisition module to sample the signal in the interested channel in the appointed time period; or, the uninteresting channels are designated, and the multichannel acquisition module is controlled not to sample the uninteresting channels in the designated time period, so that the free combination of the channels is realized, the application scene of the near-infrared brain function imaging is greatly expanded, and the additional cost is not required.
Example 3
In this embodiment, an LED driving circuit and an LED patch are integrated in the transmitting probe, and an APD photoelectric conversion circuit, a signal amplification circuit, and a filter circuit are integrated in the receiving probe.
As shown in fig. 3, two circuit boards are disposed in the transmitting probe of this embodiment, a power supply and an LED driving circuit are integrated on the upper circuit board, and an LED driving circuit and a multiband single LED patch are integrated on the lower circuit board. The power supply and the LED driving circuit are integrated in the transmitting probe, so that the volume of the control panel is reduced on the basis of not changing the volume of the existing transmitting probe, meanwhile, the input signal entering the transmitting probe is simplified, and the anti-interference capability is improved.
The front end of the emission probe is provided with an emission optical fiber channel used for guiding light emitted by at least one group of LED components out of the emission probe; the tail end of the emission probe is provided with a first pluggable interface used for electrically connecting the emission probe with the control component through the first pluggable interface.
The front end of the emission probe is connected with the head of a human body, the tail end of the emission probe is connected with the control assembly, and the control assembly sends out a driving carrier wave to drive the emission probe to output a detection light signal. Therefore, the power-on signal between the transmitting probe and the control assembly is subjected to information interaction, and the problem of signal interference in optical fiber signal transmission is avoided.
The transmitting probe is detachably connected with the control assembly through the first pluggable interface.
As shown in fig. 4, two circuit boards are disposed in the receiving probe of this embodiment, an APD photoelectric conversion circuit is integrated on the lower circuit board, and a signal amplification circuit and a filter circuit are integrated on the upper circuit board.
The front end of the receiving probe is provided with a receiving optical fiber channel for guiding the scattered light from the head of the human body into the receiving probe; the tail end of the receiving probe is provided with a second pluggable interface for electrically connecting the receiving probe with the control component through the second pluggable interface.
The front end of the receiving probe is connected with the head of a human body, the tail end of the receiving probe is connected with the control assembly, and scattered light from the head of the human body is converted by the receiving probe and then transmitted to the control assembly in the form of an electric signal. Therefore, information interaction is carried out between the receiving probe and the control assembly through electric signals, and the anti-interference capacity is improved.
The receiving probe is detachably connected with the control assembly through the second pluggable interface.
In the embodiment, the power supply and the LED driving circuit are integrated in the transmitting probe, so that the space at the tail part of the transmitting probe is fully utilized, the size of the conventional probe is not changed, the size of a control assembly is reduced, and the portability of the whole system is improved.
Example 4
This embodiment provides a housing for mounting the transmitting probe or the receiving probe described in embodiment 3. The shell is a combination of a cylindrical structure and a conical structure. The middle tip of the conical structure of the shell is used for arranging an optical fiber channel. The end of the cylindrical structure of the shell is provided with a cover body.
The cover bodies of the transmitting probe and the receiving probe are respectively provided with a pluggable interface for being electrically connected with the control panel through a circuit. The cover body can be made of plastic.
And a cavity formed by the cylindrical structure of the shell is used for integrating an LED assembly or a circuit board of a photoelectric conversion circuit or a signal processing circuit.
The housing diameter of this embodiment is about 1.2 cm.
The volume of the integrated LED patch on the circuit board is very small, and the length and width of the integrated LED patch can be about 2 mm.
Example 5
The embodiment provides a channel pluggable portable near-infrared brain function imaging method, which is realized by adopting the system, wherein the system comprises a control component, a transmitting probe and a receiving probe. The control assembly is electrically connected with the transmitting probe and the receiving probe. The control component is connected with the management terminal.
As shown in fig. 5, the method includes:
and S1, the control component receives a channel selection instruction sent by the management terminal, wherein the channel selection instruction comprises interested channel information (such as a number), uninteresting channel information, an interested or uninteresting preset time period and the like, and after the control component receives the instruction, the control component closes the uninteresting channel and determines an available channel.
And S2, the control component sends a high-frequency carrier wave with fixed frequency, the high-frequency carrier wave is transmitted into the emission probe in an electric signal mode, the LED patch is driven to emit light, and the emitted light is incident to the brain skin.
And S3, the light scattered by the brain skin enters the receiving probe, is subjected to photoelectric conversion by the receiving probe, is amplified and filtered after being converted into an electric signal, and is transmitted to the control component in an electric signal mode.
And S4, the control component receives the feedback signal, samples the feedback signal in the appointed available channel at the AD sampling frequency with the same frequency as the high-frequency carrier, and extracts and restores the original cerebral blood flow signal while acquiring the signal.
The embodiment firstly sends the driving carrier wave in the mode of an electric signal, drives the transmitting probe to transmit an optical signal and irradiates the brain skin, then the receiving probe receives and processes a feedback optical signal generated by the scattering of the brain skin, and then the feedback optical signal is transmitted to the control assembly in the mode of the electric signal, the control assembly collects and extracts the signal in the preselected specified channel, and the collection frequency is consistent with the frequency of the driving carrier wave, so that the original cerebral blood flow signal can be extracted and restored while the signal is collected, the restoration and extraction of the signal can be realized without a special signal demodulation chip, and the extracted cerebral blood flow signal has higher restoration degree.
Finally, it should be noted that: the above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and the modifications or the substitutions do not make the essence of the corresponding technical solutions deviate from the technical solutions of the embodiments of the present invention.
Claims (10)
1. A channel pluggable portable near-infrared brain function imaging system is characterized by comprising a control assembly, wherein the control assembly is respectively in signal transmission with at least one transmitting probe and at least one receiving probe in an electric signal mode; at least one emission probe is provided with a first pluggable interface and is used for being electrically connected with the control assembly through the first pluggable interface and receiving the driving carrier wave sent by the control assembly; at least one receiving probe is provided with a second pluggable interface and is used for being electrically connected with the control assembly through the second pluggable interface and sending a feedback signal to the control assembly; the control assembly is provided with a multi-channel acquisition module for sampling a feedback signal of a specified channel, and the sampling frequency of the multi-channel acquisition module is the same as the frequency of the driving carrier wave.
2. The system according to claim 1, wherein the control component is connected to a management terminal, and is configured to determine an available channel according to a channel selection command sent by the management terminal, and extract a feedback signal transmitted by the available channel.
3. The channel pluggable portable near-infrared brain function imaging system according to claim 2, wherein the management terminal comprises a hardware terminal or a software application.
4. The channel pluggable portable near-infrared brain function imaging system according to claim 1, wherein the driving carrier is a high-frequency carrier with a fixed frequency, and the high-frequency carrier is transmitted to the transmitting probe in an electrical signal manner and is used for driving an LED patch in the transmitting probe to emit light.
5. The channel pluggable portable near-infrared brain function imaging system according to claim 1, wherein the feedback signal is a modulated wave signal modulated by a driving carrier.
6. The channel pluggable portable near-infrared brain function imaging system according to claim 1, wherein the emission probe is integrated with an LED driving circuit and an LED patch.
7. The portable near-infrared brain function imaging system of claim 1, wherein the receiving probe has integrated therein a photoelectric conversion circuit and a signal processing circuit.
8. A channel pluggable portable near-infrared brain function imaging method implemented by the system of any one of claims 1-7, the method comprising:
sending a driving carrier wave to drive a transmitting probe to emit probe light;
the receiving probe collects a feedback signal based on the detection light;
and receiving a feedback signal, and sampling the feedback signal in the specified channel, wherein the sampling frequency is the same as the frequency of the driving carrier wave.
9. The method of claim 8, further comprising: and acquiring a channel selection instruction, determining an available channel, and extracting a feedback signal transmitted by the available channel.
10. The channel pluggable portable nir brain function imaging method according to claim 9, wherein for the unavailable channel, the feedback signal inputted via the unavailable channel is not sampled for a preset time period.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111431164.6A CN113951833A (en) | 2021-11-29 | 2021-11-29 | Channel pluggable portable near-infrared brain function imaging system and method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111431164.6A CN113951833A (en) | 2021-11-29 | 2021-11-29 | Channel pluggable portable near-infrared brain function imaging system and method |
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