CN113940910A - Gingko extract toning lotion - Google Patents
Gingko extract toning lotion Download PDFInfo
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- CN113940910A CN113940910A CN202111362456.9A CN202111362456A CN113940910A CN 113940910 A CN113940910 A CN 113940910A CN 202111362456 A CN202111362456 A CN 202111362456A CN 113940910 A CN113940910 A CN 113940910A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9771—Ginkgophyta, e.g. Ginkgoaceae [Ginkgo family]
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Cosmetics (AREA)
Abstract
The invention provides a gingko extract toning lotion, and particularly relates to the technical field of skin care products, wherein the gingko extract toning lotion comprises the following components in parts by weight: 5-15 parts of ginkgo extract, 1-10 parts of black pepper extract, 5-10 parts of motherwort extract, 1-10 parts of dendrobium officinale extract, 5-20 parts of hydrolyzed collagen, 5-20 parts of hyaluronic acid, 30-50 parts of glycerol and a proper amount of distilled water. The toning lotion disclosed by the invention has the effects of whitening, removing freckles, brightening and replenishing water, and is quick in effect, free of rebound and free of stimulation to skin.
Description
Technical Field
The invention relates to the technical field of skin care products, and particularly relates to a gingko extract toning lotion.
Background
The cosmetic water is generally transparent liquid, and can remove dirt and oily secretion on skin, keep stratum corneum of skin with appropriate water content, promote skin physiological function, soften skin and prevent pachylosis. The cosmetic water comprises: softening lotion for keeping skin soft and moist, astringent lotion for supplementing water and moisture of horny layer of skin, washing lotion for removing light makeup or using as face cleaning agent, and multi-layer lotion composed of oil layer-water layer or water layer-powder layer or multiple layers. The cosmetic water is classified according to functionality into brightening, yellow removing, whitening, freckle removing, moisturizing, oil controlling, anti-allergy, bactericidal or multifunctional cosmetic water and the like.
Melanin is an amino acid derivative, and 20-25 years old is the active period of melanin precipitate formation. They are present in the middle of the cells of the basal layer of the skin, a melanogenic substance or a chromoplast. The melanoblast secretes Maillarin pigment, when ultraviolet rays (B wave and A wave) irradiate the skin (the B wave, namely UVB acts on the basal layer of the skin), the skin is in a self-protection state, namely the Maillarin pigment is stimulated by the ultraviolet rays, the activity of tyrosinase is activated, the skin cells are protected, and dopa in the skin releases melanin through the oxidation of activated tyrosine. Melanin moves layer by layer through cell metabolism, and forms freckles, sunburn, black spots and the like on the skin epidermis.
In recent years, domestic researches on whitening, freckle removing, brightening and moisturizing cosmetics are not superior, but many existing products are complex and imperfect in formula, single in effect, short in effect, high in rebound and great in side effect.
Disclosure of Invention
The invention aims to provide the gingko extract toning lotion which has the effects of whitening, removing freckles, brightening and replenishing water, and is quick in effect, free of rebound and free of stimulation to skin.
In order to achieve the above object, the present invention provides the following technical solutions:
the invention provides a ginkgo extract toning lotion which comprises the following components in parts by weight: 5-15 parts of ginkgo extract, 1-10 parts of black pepper extract, 5-10 parts of motherwort extract, 1-10 parts of dendrobium officinale extract, 5-20 parts of hydrolyzed collagen, 5-20 parts of hyaluronic acid, 30-50 parts of glycerol and a proper amount of distilled water.
Preferably, the toning lotion comprises the following components in parts by weight: 8-10 parts of ginkgo extract, 3-5 parts of black pepper extract, 8-10 parts of motherwort extract, 3-5 parts of dendrobium officinale extract, 10-15 parts of hydrolyzed collagen, 10-15 parts of hyaluronic acid, 40-45 parts of glycerol and a proper amount of distilled water.
Preferably, the ginkgo biloba extract raw material is ginkgo biloba leaves.
Preferably, the motherwort extract raw material is one or more of motherwort flowers, motherwort stems and motherwort leaves.
Preferably, the preparation method of the ginkgo biloba extract comprises the following steps: mixing pulverized semen Ginkgo with water, pretreating with ultrasonic wave, boiling for extraction to obtain crude extractive solution, and purifying by ion exchange chromatography to obtain semen Ginkgo extract. .
Preferably, the preparation method of the black pepper extract and the motherwort herb extract comprises the following steps: extracting the black pepper and the motherwort herb raw materials respectively with 65-85% ethanol under reflux for 2-4 times, combining the extracting solutions, and concentrating by 3-5 times to obtain the black pepper extract and the motherwort herb extract.
Preferably, the preparation method of the dendrobium officinale extract comprises the following steps: mixing the dendrobium officinale pulverized into powder with water, performing ultrasonic pretreatment, filtering to obtain filter residues, performing reflux extraction on the filter residues for 2-4 times by using 35-45% ethanol, combining extracting solutions, and concentrating by 4-6 times to obtain the dendrobium officinale extract.
The invention provides a preparation method of toning lotion, which comprises the following steps: uniformly mixing the hydrolyzed collagen with the distilled water, adding the hyaluronic acid and the glycerol, uniformly mixing, then adding the ginkgo biloba extract, the black pepper extract, the motherwort herb extract and the dendrobium officinale extract, and uniformly mixing to obtain the ginkgo biloba extract toning lotion.
Compared with the prior art, the invention has the following beneficial effects:
the main components of the cosmetic are natural plant extracts, the formula is reasonable, the ginkgo biloba extract, the black pepper extract, the motherwort extract and the dendrobium officinale extract are combined for use, the synergistic effect is achieved, and compared with the cosmetic lotion with a single action mechanism, the ginkgo biloba extract cosmetic lotion can inhibit the activity of tyrosinase, dispel melanin in cells, and achieve multiple effects of whitening, removing freckles, brightening and replenishing water.
The toning lotion has quick response, no rebound and no stimulation to skin, and can be used for a long time.
Detailed Description
The invention provides a gingko extract toning lotion, which preferably comprises the following components in parts by weight: 5-15 parts of ginkgo extract, 1-10 parts of black pepper extract, 5-10 parts of motherwort extract, 1-10 parts of dendrobium officinale extract, 5-20 parts of hydrolyzed collagen, 5-20 parts of hyaluronic acid, 30-50 parts of glycerol and a proper amount of distilled water; more preferably comprises the following components in parts by weight: 8-10 parts of ginkgo extract, 3-5 parts of black pepper extract, 8-10 parts of motherwort extract, 3-5 parts of dendrobium officinale extract, 10-15 parts of hydrolyzed collagen, 10-15 parts of hyaluronic acid, 40-45 parts of glycerol and a proper amount of distilled water.
In the present invention, the ginkgo biloba extract raw material is preferably ginkgo biloba leaves. The ginkgo leaf is dry leaf of ginkgo of Ginkgoaceae, the main chemical components of the ginkgo leaf are polysaccharide, flavonoid and terpene lactone compounds, the protein content is high, and the ginkgo leaf also contains abundant vitamin C, vitamin D, carotene, calcium, phosphorus, boron and selenium, and has the effects of resisting senility and removing wrinkles on skin. .
In the invention, the motherwort extract raw material is preferably one or more of motherwort flowers, motherwort stems and motherwort leaves, and more preferably motherwort leaves. The motherwort herb contains alkaloids, flavonoids, diterpenes, fatty acids, volatile oils, motherwort polysaccharide and the like, and has the effects of preventing radiation, resisting free radicals, nourishing and moistening, diminishing inflammation and inhibiting bacteria on skin.
In the present invention, the preparation method of the ginkgo biloba extract is preferably: mixing pulverized semen Ginkgo with water, pretreating with ultrasonic wave, boiling for extraction to obtain crude extractive solution, and purifying by ion exchange chromatography to obtain semen Ginkgo extract. The temperature of the ultrasonic pretreatment is preferably 30-45 ℃, the time is preferably 20-30 min, and the boiling time is preferably 0.5-1 h.
In the invention, the preparation method of the black pepper extract and the motherwort extract comprises the following steps: extracting the black pepper and the motherwort herb raw materials respectively with 65-85% ethanol under reflux for 2-4 times, combining the extracting solutions, and concentrating by 3-5 times to obtain the black pepper extract and the motherwort herb extract. The black pepper extract disclosed by the invention has the effects of promoting blood circulation and skin absorption, and the motherwort extract has the effects of preventing radiation, resisting free radicals, nourishing and moistening, diminishing inflammation and inhibiting bacteria.
In the invention, the preparation method of the dendrobium officinale extract comprises the following steps: mixing the dendrobium officinale pulverized into powder with water, performing ultrasonic pretreatment, filtering to obtain filter residues, performing reflux extraction on the filter residues for 2-4 times by using 35-45% ethanol, combining extracting solutions, and concentrating by 4-6 times to obtain the dendrobium officinale extract. The dendrobium officinale extract disclosed by the invention has the effects of resisting oxidation, promoting melanin metabolism and inhibiting tyrosinase activity.
The invention also provides a preparation method of the toning lotion, and the preferable preparation method comprises the following steps: uniformly mixing the hydrolyzed collagen with the distilled water, adding the hyaluronic acid and the glycerol, uniformly mixing, then adding the ginkgo biloba extract, the black pepper extract, the motherwort herb extract and the dendrobium officinale extract, and uniformly mixing to obtain the ginkgo biloba extract toning lotion. The toning lotion prepared by the preparation method of the toning lotion is pure and free of impurities.
In the present invention, all the raw material components are commercially available products well known to those skilled in the art unless otherwise specified.
The technical solution of the present invention will be clearly and completely described below with reference to the embodiments of the present invention. It is to be understood that the described embodiments are merely exemplary of the invention, and not restrictive of the full scope of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
The preparation method of the ginkgo leaf extract comprises the following steps: mixing 60-mesh pulverized semen Ginkgo powder with water, pretreating with ultrasonic wave at 40 deg.C for 25min, boiling for 1 hr to obtain crude extractive solution, filtering, and purifying by ion exchange chromatography to obtain semen Ginkgo extract.
The preparation method of the black pepper extract and the leonurus japonicus leaf extract comprises the following steps: extracting pulverized 60-mesh fructus Piperis and herba Leonuri with 70% ethanol under reflux for 3 times, mixing extractive solutions, and concentrating 4 times to obtain fructus Piperis extract and herba Leonuri extract.
The preparation method of the dendrobium officinale extract comprises the following steps: mixing the dendrobium officinale crushed into 80 meshes with water, adopting ultrasonic pretreatment, filtering to obtain filter residue, carrying out reflux extraction on the filter residue for 3 times by using 40% ethanol, combining extracting solutions, and concentrating by 5 times to obtain the dendrobium officinale extract.
Example 2
Uniformly mixing the hydrolyzed collagen with the distilled water, adding the hyaluronic acid and the glycerol, uniformly mixing, then adding the ginkgo biloba extract, the black pepper extract, the motherwort herb extract and the dendrobium officinale extract, and uniformly mixing to obtain the ginkgo biloba extract toning lotion.
Example 3
A gingko extract toning lotion comprises the following components in parts by weight: 9 parts of ginkgo extract, 4 parts of black pepper extract, 9 parts of motherwort extract, 4 parts of dendrobium officinale extract, 14 parts of hydrolyzed collagen, 14 parts of hyaluronic acid, 42 parts of glycerol and a proper amount of distilled water.
The preparation methods of the ginkgo biloba extract, the black pepper extract, the motherwort herb extract and the dendrobium officinale extract are the same as the example 1.
The preparation method of the toning lotion is the same as that of the example 2.
Example 4
A gingko extract toning lotion comprises the following components in parts by weight: 8 parts of ginkgo extract, 3 parts of black pepper extract, 8 parts of motherwort extract, 3 parts of dendrobium officinale extract, 10 parts of hydrolyzed collagen, 10 parts of hyaluronic acid, 40 parts of glycerol and a proper amount of distilled water.
The preparation methods of the ginkgo biloba extract, the black pepper extract, the motherwort herb extract and the dendrobium officinale extract are the same as the example 1.
The preparation method of the toning lotion is the same as that of the example 2.
Example 5
A gingko extract toning lotion comprises the following components in parts by weight: 10 parts of ginkgo extract, 5 parts of black pepper extract, 10 parts of motherwort extract, 5 parts of dendrobium officinale extract, 15 parts of hydrolyzed collagen, 15 parts of hyaluronic acid, 45 parts of glycerol and a proper amount of distilled water.
The preparation methods of the ginkgo biloba extract, the black pepper extract, the motherwort herb extract and the dendrobium officinale extract are the same as the example 1.
The preparation method of the toning lotion is the same as that of the example 2.
Comparative example 1
The ginkgo biloba extract of example 3 was removed and the other components and preparation method were the same as in example 3.
Comparative example 2
The black pepper extract of example 3 was removed and the other components and preparation method were the same as example 3.
Comparative example 3
The motherwort extract in example 3 was removed, and other components and preparation method were the same as in example 3.
Comparative example 4
The dendrobium officinale extract in the example 3 is removed, and other components and the preparation method are the same as the example 3.
Example 6
Selecting 56 volunteers as subjects, wherein the subjects are female, the ages of the subjects are 20-45 years old, the subjects are divided into 7 groups, and the facial melanin content of each group is measured and the use evaluation on the whitening, freckle removing, brightening and moisturizing effects is carried out on 8 persons in each group.
Washing the face of a subject with warm water, applying a proper amount of lotion on the face, beating until the lotion is completely absorbed, repeating the steps three times, using the lotion once in the morning and at night every day, continuously using the lotion for 7 days, measuring the content of facial melanin of the subject before and after using the lotion for 7 days by using a skin tester, and simultaneously recording the use evaluation of the lotion by the subject. The results are shown in Table 1.
TABLE 1 subject facial melanin content and post-use evaluation results
Typical example 1 king women, 24 years old, dark and dull face, especially the skin of forehead, nasal wing and chin is obviously black and greasy, and sunburn of cheeks is light brown, after 7 days of using the gingko extract toning lotion of the invention, the face is bright, the skin color of forehead, nasal wing and chin is white and has no greasy phenomenon, the color spots of cheeks obviously disappear, no side effect is caused, the gingko extract toning lotion is not used for 4 days, and the skin still keeps the improved effect.
Typical example 2 of a red woman, age 40, uneven facial color, dark eyelid, more spots on two cheeks and frequent dry skin feeling, the facial skin becomes white, the skin is bright, the facial color is uniform, the eyelid is obviously whitened after 7 days of using the gingko extract toning lotion, and a user feels moist, the dry feeling disappears, and no stimulation or anaphylaxis exists.
In a typical example, 3-benzyl women are 25 years old, the skin becomes yellow and rough, and the number of face freckles is large, so that after 7 days of using the gingko extract toning lotion, the yellow face disappears, the skin is bright and white, the face freckles obviously disappear, the gingko extract toning lotion is not used at intervals of 3 days, and the skin still keeps the effect after improvement.
The experimental data show that the ginkgo extract cosmetic prepared by the invention has the comprehensive effects of obviously whitening, removing freckles, brightening and moisturizing, has no rebound after use, and can thoroughly improve the skin.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, various modifications and decorations can be made without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.
Claims (8)
1. The gingko extract toning lotion is characterized by comprising the following components in parts by weight: 5-15 parts of ginkgo extract, 1-10 parts of black pepper extract, 5-10 parts of motherwort extract, 1-10 parts of dendrobium officinale extract, 5-20 parts of hydrolyzed collagen, 5-20 parts of hyaluronic acid, 30-50 parts of glycerol and a proper amount of distilled water.
2. The lotion according to claim 1, comprising the following components in parts by weight: 8-10 parts of ginkgo extract, 3-5 parts of black pepper extract, 8-10 parts of motherwort extract, 3-5 parts of dendrobium officinale extract, 10-15 parts of hydrolyzed collagen, 10-15 parts of hyaluronic acid, 40-45 parts of glycerol and a proper amount of distilled water.
3. The astringent of claim 1, wherein the ginkgo biloba extract material is ginkgo biloba leaves.
4. The astringent of claim 1, wherein the motherwort extract is prepared from one or more of flowers, stems and leaves of motherwort.
5. The astringent of claim 1, wherein the ginkgo biloba extract is prepared by a method comprising the steps of: mixing pulverized semen Ginkgo with water, pretreating with ultrasonic wave, boiling for extraction to obtain crude extractive solution, and purifying by ion exchange chromatography to obtain semen Ginkgo extract.
6. The lotion according to claim 1, wherein the black pepper extract and the motherwort extract are prepared by a method comprising the steps of: extracting the black pepper and the motherwort herb raw materials respectively with 65-85% ethanol under reflux for 2-4 times, combining the extracting solutions, and concentrating by 3-5 times to obtain the black pepper extract and the motherwort herb extract.
7. The toning lotion according to claim 1, wherein the preparation method of the dendrobium officinale extract comprises the following steps: mixing the dendrobium officinale pulverized into powder with water, performing ultrasonic pretreatment, filtering to obtain filter residues, performing reflux extraction on the filter residues for 2-4 times by using 35-45% ethanol, combining extracting solutions, and concentrating by 4-6 times to obtain the dendrobium officinale extract.
8. The method for preparing a cosmetic lotion according to claim 1, comprising the steps of: uniformly mixing the hydrolyzed collagen with the distilled water, adding the hyaluronic acid and the glycerol, uniformly mixing, then adding the ginkgo biloba extract, the black pepper extract, the motherwort herb extract and the dendrobium officinale extract, and uniformly mixing to obtain the ginkgo biloba extract toning lotion.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105434320A (en) * | 2015-12-14 | 2016-03-30 | 青岛海特新蓝生物科技有限公司 | Whitening cosmetic containing ginkgo extract, motherwort extract and ganoderma lucidum extract |
| CN105687053A (en) * | 2016-03-21 | 2016-06-22 | 成都圣雪贝佳化妆品有限公司 | Toning lotion with functions of moisturizing and resisting senility, and preparation method of toning lotion |
| CN107397697A (en) * | 2017-08-30 | 2017-11-28 | 永安康健药业（武汉）有限公司 | A kind of whitening spot-eliminating composition and its application |
| CN110354062A (en) * | 2019-08-17 | 2019-10-22 | 哈尔滨工业大学 | A kind of bitter buckwheat moisturizing sleep mask and preparation method thereof for not adding preservative |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105434320A (en) * | 2015-12-14 | 2016-03-30 | 青岛海特新蓝生物科技有限公司 | Whitening cosmetic containing ginkgo extract, motherwort extract and ganoderma lucidum extract |
| CN105687053A (en) * | 2016-03-21 | 2016-06-22 | 成都圣雪贝佳化妆品有限公司 | Toning lotion with functions of moisturizing and resisting senility, and preparation method of toning lotion |
| CN107397697A (en) * | 2017-08-30 | 2017-11-28 | 永安康健药业（武汉）有限公司 | A kind of whitening spot-eliminating composition and its application |
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