CN1139384C - 用于与细胞毒性剂***的基于类黄酮的治疗组合物 - Google Patents

用于与细胞毒性剂***的基于类黄酮的治疗组合物 Download PDF

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Publication number
CN1139384C
CN1139384C CNB998098353A CN99809835A CN1139384C CN 1139384 C CN1139384 C CN 1139384C CN B998098353 A CNB998098353 A CN B998098353A CN 99809835 A CN99809835 A CN 99809835A CN 1139384 C CN1139384 C CN 1139384C
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CN
China
Prior art keywords
vein
flavonoid
days
day
sky
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Expired - Fee Related
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CNB998098353A
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English (en)
Chinese (zh)
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CN1313765A (zh
Inventor
F
F·达罗
R·基斯
A·福里德曼
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Cephalon France SAS
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Laboratoire L Lafon SA
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Publication of CN1313765A publication Critical patent/CN1313765A/zh
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Publication of CN1139384C publication Critical patent/CN1139384C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
CNB998098353A 1998-07-15 1999-07-13 用于与细胞毒性剂***的基于类黄酮的治疗组合物 Expired - Fee Related CN1139384C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9809058A FR2781153B1 (fr) 1998-07-15 1998-07-15 Composition therapeutique a base de flavonoides destinee a etre utilisee dans le traitement des tumeurs par des agents cytotoxiques
FR98/09058 1998-07-15

Publications (2)

Publication Number Publication Date
CN1313765A CN1313765A (zh) 2001-09-19
CN1139384C true CN1139384C (zh) 2004-02-25

Family

ID=9528648

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB998098353A Expired - Fee Related CN1139384C (zh) 1998-07-15 1999-07-13 用于与细胞毒性剂***的基于类黄酮的治疗组合物

Country Status (12)

Country Link
EP (1) EP1096930A1 (ru)
JP (1) JP2002520356A (ru)
KR (1) KR20020003349A (ru)
CN (1) CN1139384C (ru)
AU (1) AU4789099A (ru)
BR (1) BR9912816A (ru)
CA (1) CA2337179A1 (ru)
EA (1) EA200100140A1 (ru)
FR (1) FR2781153B1 (ru)
IL (1) IL140588A0 (ru)
WO (1) WO2000003706A1 (ru)
ZA (1) ZA200100239B (ru)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002069949A2 (en) * 2001-03-06 2002-09-12 Prendergast Patrick T Combination therapy for reduction of toxycity of chemotherapeutic agents
EP1808172A3 (en) * 2002-03-06 2010-05-26 Activephyto Technologies Limited Botanical extract compositions and methods of use
DE60313754T2 (de) * 2002-03-06 2008-01-24 The Medical Research and Education Trust, San Diego Botanischer extrakt mit antikrebs-aktivität enthaltend isoliquiritigenin
US20030229136A1 (en) * 2002-04-18 2003-12-11 Nurulain Zaveri Novel flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents
CN1679539A (zh) * 2005-01-20 2005-10-12 吴一心 抗肿瘤的协同药物组合物
WO2006099193A2 (en) * 2005-03-11 2006-09-21 The Regents Of The University Of Michigan Chromen-4-one inhibitors of anti-apoptotic bcl-2 family members and the uses thereof
GB0808974D0 (en) * 2008-05-16 2008-06-25 Veritron Ltd Plant extract and its therapeutic use
US9808439B2 (en) * 2015-07-29 2017-11-07 Macau University Of Science And Technology Use of tangeretin in cancer treatment
US9808477B2 (en) * 2015-07-29 2017-11-07 Macau University Of Science And Technology Use of nobiletin in cancer treatment
JP6775226B2 (ja) * 2016-06-30 2020-10-28 国立大学法人広島大学 抗癌剤作用増強物質およびそれを備えた抗癌剤キット
CN106562954A (zh) * 2016-11-11 2017-04-19 黄冈师范学院 (去甲基)多甲氧基黄酮联合紫杉醇类药物在制备治疗非小细胞肺癌的药物上的应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0617304B2 (ja) * 1982-09-09 1994-03-09 理化学研究所 制癌剤
JPS5959627A (ja) * 1982-09-27 1984-04-05 Tatsuo Miyoshi 制癌剤
JPS60199817A (ja) * 1984-03-23 1985-10-09 Rikagaku Kenkyusho 制癌剤
JPS632925A (ja) * 1986-06-23 1988-01-07 Nippon Kayaku Co Ltd Cキナ−ゼ阻害剤および抗腫瘍剤
FR2633182B1 (fr) * 1988-06-23 1993-07-23 Beljanski Mirko Composition pharmaceutique anticancereuse et methode d'utilisation de l'invention
JPH04103529A (ja) * 1990-08-24 1992-04-06 Tatsuo Miyoshi 制癌剤
JPH04103532A (ja) * 1990-08-24 1992-04-06 Tatsuo Miyoshi 制癌剤
JP2514500B2 (ja) * 1991-09-14 1996-07-10 呉羽化学工業株式会社 多剤耐性抑制剤及び発現阻害剤
EP0642793A4 (en) * 1992-05-11 1995-03-29 Tsumura & Co. Apoptosis inducer.
WO1996031206A2 (en) * 1995-04-07 1996-10-10 Warner-Lambert Company Flavones and coumarins as agents for the treatment of atherosclerosis
DE29719198U1 (de) * 1997-10-29 1998-04-23 Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke, 14558 Bergholz-Rehbrücke Flavono/Flavonoid-Zubereitung

Also Published As

Publication number Publication date
EA200100140A1 (ru) 2001-06-25
JP2002520356A (ja) 2002-07-09
FR2781153A1 (fr) 2000-01-21
KR20020003349A (ko) 2002-01-12
FR2781153B1 (fr) 2001-08-03
EP1096930A1 (fr) 2001-05-09
ZA200100239B (en) 2002-01-09
CN1313765A (zh) 2001-09-19
WO2000003706A1 (fr) 2000-01-27
CA2337179A1 (en) 2000-01-27
IL140588A0 (en) 2002-02-10
BR9912816A (pt) 2001-05-08
AU4789099A (en) 2000-02-07

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