CN113916495A - Experimental device for simulating cardiovascular hemodynamic characteristics after lower limb amputation - Google Patents
Experimental device for simulating cardiovascular hemodynamic characteristics after lower limb amputation Download PDFInfo
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- CN113916495A CN113916495A CN202111152277.2A CN202111152277A CN113916495A CN 113916495 A CN113916495 A CN 113916495A CN 202111152277 A CN202111152277 A CN 202111152277A CN 113916495 A CN113916495 A CN 113916495A
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- 230000002526 effect on cardiovascular system Effects 0.000 title claims abstract description 39
- 230000000004 hemodynamic effect Effects 0.000 title claims abstract description 29
- 210000003141 lower extremity Anatomy 0.000 title claims abstract description 19
- 238000011542 limb amputation Methods 0.000 title claims abstract description 9
- 238000004088 simulation Methods 0.000 claims abstract description 71
- 210000001367 artery Anatomy 0.000 claims abstract description 44
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 43
- 210000003090 iliac artery Anatomy 0.000 claims abstract description 41
- 230000002572 peristaltic effect Effects 0.000 claims abstract description 19
- 238000003860 storage Methods 0.000 claims abstract description 17
- 238000002266 amputation Methods 0.000 claims description 13
- 238000003825 pressing Methods 0.000 claims description 12
- 230000005611 electricity Effects 0.000 claims description 6
- 210000002254 renal artery Anatomy 0.000 claims description 6
- 238000010146 3D printing Methods 0.000 claims description 4
- 210000001168 carotid artery common Anatomy 0.000 claims description 3
- 210000004249 mesenteric artery inferior Anatomy 0.000 claims description 3
- 210000001363 mesenteric artery superior Anatomy 0.000 claims description 3
- 229920001296 polysiloxane Polymers 0.000 claims description 3
- 210000003270 subclavian artery Anatomy 0.000 claims description 3
- 210000002168 brachiocephalic trunk Anatomy 0.000 claims description 2
- 230000010349 pulsation Effects 0.000 abstract description 9
- 210000004204 blood vessel Anatomy 0.000 abstract description 5
- 239000007788 liquid Substances 0.000 description 9
- 230000017531 blood circulation Effects 0.000 description 7
- 210000004369 blood Anatomy 0.000 description 5
- 239000008280 blood Substances 0.000 description 5
- 238000002474 experimental method Methods 0.000 description 3
- 230000010247 heart contraction Effects 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 238000010009 beating Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000011132 hemopoiesis Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000000737 periodic effect Effects 0.000 description 2
- 230000004962 physiological condition Effects 0.000 description 2
- 230000002792 vascular Effects 0.000 description 2
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 210000003484 anatomy Anatomy 0.000 description 1
- 230000008321 arterial blood flow Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 230000000747 cardiac effect Effects 0.000 description 1
- 210000000748 cardiovascular system Anatomy 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 230000001066 destructive effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 230000001121 heart beat frequency Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000012623 in vivo measurement Methods 0.000 description 1
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- 238000012986 modification Methods 0.000 description 1
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- 238000012544 monitoring process Methods 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
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- 238000000827 velocimetry Methods 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01M—TESTING STATIC OR DYNAMIC BALANCE OF MACHINES OR STRUCTURES; TESTING OF STRUCTURES OR APPARATUS, NOT OTHERWISE PROVIDED FOR
- G01M10/00—Hydrodynamic testing; Arrangements in or on ship-testing tanks or water tunnels
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- Physics & Mathematics (AREA)
- Fluid Mechanics (AREA)
- General Physics & Mathematics (AREA)
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Abstract
The invention belongs to the technical field of measuring the blood vessel hemodynamic characteristics, and discloses an experimental device for simulating the cardiovascular hemodynamic characteristics after lower limb amputation, which comprises a water storage barrel, a telescopic motor, a data acquisition system and a PC terminal, wherein the water storage barrel is communicated with a peristaltic pump through a water guide pipe, the peristaltic pump is communicated with a heart pulsation simulation cavity, the heart pulsation simulation cavity is communicated with a check valve and a first pressure sensor, the first pressure sensor is communicated with a compliance simulation pipe, the compliance simulation pipe is communicated with a cardiovascular main artery model, the cardiovascular main artery model comprises a left iliac artery, a right iliac artery and other artery simulation pipes, the left iliac artery and the right iliac artery are communicated with a second pressure sensor, an electromagnetic flowmeter and a high-precision flow stop valve, and the other artery simulation pipes are communicated with a high-precision flow stop valve; the invention solves the problem that the prior art can not simulate the cardiovascular hemodynamic environment after lower limb amputation, and is suitable for the simulation experiment of the cardiovascular hemodynamic characteristics after lower limb amputation.
Description
Technical Field
The invention relates to the technical field of measurement of vascular hemodynamic characteristics, in particular to an experimental device for simulating cardiovascular hemodynamic characteristics after lower limb amputation.
Background
Hemodynamics (hemodynamics) refers to the mechanics of blood flowing in the cardiovascular system, and is mainly used for researching parameters such as blood flow volume, blood flow resistance, blood pressure and the like and the mutual relation among the parameters; the basic principle of hemodynamics is the same as that of general hydrodynamics, but because the vascular system is a relatively complex elastic pipeline system, blood is a liquid containing multiple components such as blood cells and colloidal substances rather than an ideal liquid, and therefore hemodynamics not only has the common characteristics of general hydrodynamics, but also has the characteristics of the blood dynamics.
Amputation is a very destructive treatment, which results in significant changes in the anatomy of the body, and thus in the hemodynamic parameters in the blood vessels, which are closely related to some cardiovascular diseases. Due to the limitation of experimental conditions and environment, accurate in vivo measurement and monitoring of arterial blood flow dynamic parameters of a human body are difficult to realize, and are usually performed through in vitro simulation experiments at present. In the extracorporeal simulation experiment, the flow similarity principle is utilized, an extracorporeal experiment platform is built to simulate the flow of blood in a human blood vessel, and corresponding hemodynamic parameters are obtained through a measurement and control technology.
Disclosure of Invention
The invention aims to provide an experimental device for simulating cardiovascular hemodynamic characteristics after amputation of lower limbs, and aims to solve the problem that the prior art lacks an experimental device for simulating pulsating blood flow generated by heart cycle pulsation and cannot collect data of hemodynamic parameters to reflect the hemodynamic characteristics under real physiological conditions after amputation.
In order to achieve the above purpose, the invention provides the following technical scheme:
the basic technical scheme provided by the invention is as follows: the utility model provides an experimental apparatus for simulation lower limb amputation back cardiovascular blood flow dynamics characteristic, includes water storage bucket, flexible motor, data acquisition system and PC terminal, the water storage bucket has the peristaltic pump through the aqueduct intercommunication, the delivery port intercommunication of peristaltic pump has heart beat simulation chamber, flexible motor is used for the cycle to press heart beat simulation chamber, the delivery port intercommunication in heart beat simulation chamber has first pressure sensor, first pressure sensor's delivery port intercommunication has compliance analog tube, compliance analog tube is the silicone tube, the delivery port intercommunication of compliance analog tube has cardiovascular main artery model, cardiovascular main artery model includes left iliac artery, right iliac artery and other artery analog tubes, left iliac artery with right iliac artery all communicates and has second pressure sensor and electromagnetic flowmeter, left iliac artery, The right iliac artery with other artery analog tubes all communicate there is high accuracy flow stop valve, the left iliac artery the right iliac artery with the delivery port of other artery analog tubes all with the water storage bucket intercommunication, first pressure sensor the second pressure sensor with electromagnetic flowmeter all with data acquisition system intercommunication, data acquisition system with the PC terminal electricity is connected.
The principle of the basic technical scheme is as follows: the water storage barrel is filled with liquid for simulating blood flow, the peristaltic pump is started to enable solution in the water storage barrel to enter the water guide pipe, the flow of the solution in the water guide pipe is related to the flow of blood output by a human heart, the heart pulsation simulation cavity is periodically pressed by the working of the telescopic motor to simulate heart pulsation, the first pressure sensor detects the pressure of the liquid flowing out of the heart pulsation simulation cavity, the solution then enters the cardiovascular main artery model through the compliance simulation pipe, the solution in the cardiovascular main artery model respectively enters the left iliac artery, the right iliac artery and other artery simulation pipes, the second pressure sensor and the electromagnetic flow meter respectively detect the pressure and the flow of the liquid of the left iliac artery and the right iliac artery, amputations of different degrees are simulated by adjusting high-precision flow stop valves at the left and right iliac arteries, the data acquisition system is used for acquiring hemodynamics parameters of the left iliac artery, the right iliac artery and other artery simulation pipes, the PC terminal is used for displaying the liquid parameters and the near physiological waveform, and the solution flowing out of the data acquisition system flows back into the water storage barrel.
The beneficial effects of the basic technical scheme are as follows: after the whole experimental device is started, the solution in the system can simulate the circulation flow between the blood vessel and the heart after the hemopoiesis of the human heart, so that the waste of a large amount of resources is avoided; the peristaltic pump can select and adjust the rate of the hemopoiesis of the heart as required, and the flexible motor presses the heart pulsation simulation cavity periodically to simulate the pulsation of the heart, so that the data acquisition system can well acquire solution flow dynamic parameters which are the same as pulsating blood flow generated by the simulation of the heart periodic pulsation, and the hemodynamics characteristics of the amputated lower limb under the human physiological condition can be truly reflected; the real reliability of the simulation data can be further ensured by observing the pressure sensor and the electromagnetic flowmeter in real time and adjusting the peristaltic pump telescopic motor; compliance of a compliance simulation tube-simulated vessel; the cardiovascular main artery model comprises a left iliac artery, a right iliac artery and an artery simulation tube, which are similar to the main artery of a human body, and further ensures the reliability of simulation data.
Preferably, an output shaft of the extension motor is connected with a pressing plate, the pressing plate is fixedly connected with the outer tube wall of the heart beat simulation cavity, and the diameter of the pressing plate is 1/3 the length of the heart beat simulation cavity.
Through the arrangement, the pressing plate presses the heart beating simulation cavity periodically during the operation of the telescopic motor, the stress of the heart beating simulation cavity is uniform in the process of being pressed, and the phenomenon that the local pressed deformation of the heart beating simulation cavity causes uneven beating and influences the simulation effect is avoided.
Preferably, the water inlet and the water outlet of the heart beat simulation cavity are both communicated with a check valve, and the check valve enables the solution in the heart beat simulation cavity to flow from the peristaltic pump to one side of the first pressure sensor only.
Through the aforesaid setting, when heart beat simulation chamber received to press, its inboard solution probably goes out water from water inlet and delivery port both ends, all is provided with the check valve at water inlet and delivery port after, and the water in the heart beat simulation intracavity can only flow to delivery port one side from water inlet one side, avoids the solution in the heart beat simulation intracavity to flow from the water inlet and influences the periodic cycle law of whole device internal water, further ensures that the flow mechanics characteristic that the simulation obtained is unanimous with real blood flow mechanics characteristic.
Preferably, the output of the peristaltic pump is 6L/min.
With the above arrangement, the output is consistent with the cardiac output of normal adults.
Preferably, flexible motor electricity is connected with Arduino control panel, Arduino control panel with the PC terminal electricity is connected.
Through the setting, the stretching cycle of the stretching motor can be adjusted according to actual needs so as to simulate different beating rates of the heart, the control and the adjustment are convenient, and the application range is wide.
Preferably, the cardiovascular main artery model is manufactured by means of 3D printing, and the cardiovascular main artery model is completely transparent.
Through the arrangement, the flow field speed in the model can be conveniently measured by using an ion image velocimetry (PIV), the cardiovascular main artery model obtained by 3D printing has high similarity with a real main artery, the production and the manufacture are convenient, and the actual shape of the model is easy to adjust; the completely transparent cardiovascular main artery model is convenient for experimenters to observe the internal water flow dynamics characteristics of the cardiovascular main artery model.
Preferably, the other artery mimic tubes include brachiocephalic trunk, common carotid artery, subclavian artery, celiac trunk, superior mesenteric artery, inferior mesenteric artery, left renal artery, and right renal artery.
Through the arrangement, the artery simulation tube is complete including the covered artery tube, the similarity of the cardiovascular main artery model and the real main artery is high, and the authenticity of simulation parameters is further improved.
Drawings
FIG. 1 is a schematic structural diagram of an experimental device for simulating cardiovascular hemodynamic characteristics after lower limb amputation according to the present invention;
the names of corresponding labels in the drawings are:
water storage bucket 1, aqueduct 2, peristaltic pump 3, flexible motor 4, heart beat simulation chamber 5, check valve 6, first pressure sensor 7, compliance simulation pipe 8, cardiovascular main artery model 9, left iliac artery 10, right iliac artery 11, second pressure sensor 12, electromagnetic flowmeter 13, Arduino control panel 14, high accuracy flow stop valve 15, data acquisition system 16, PC terminal 17.
Detailed Description
The invention is described in further detail below with reference to the following figures and embodiments:
as shown in figure 1, the experimental device for simulating the cardiovascular hemodynamic characteristics after amputation of lower limbs comprises a water storage barrel 1, a telescopic motor 4, a data acquisition system 16 and a PC terminal 17, wherein the water storage barrel 1 is communicated with a peristaltic pump 3 through a water guide pipe 2, the output quantity of the peristaltic pump 3 is 6L/min, the water outlet of the peristaltic pump 3 is communicated with a heart beat simulation cavity 5, the water inlet and the water outlet of the heart beat simulation cavity 5 are both communicated with a check valve 6, the check valve 6 enables a solution in the heart beat simulation cavity 5 to only flow out of the water outlet, the telescopic motor 4 is connected with an Arduino control plate 14 through a conductive wire, the output shaft of the telescopic motor 4 is fixedly connected with a pressing plate, the pressing plate is used for periodically pressing the heart beat simulation cavity 5, the pressing plate is 1/3 which is the length of the heart beat simulation cavity 5, the water outlet of the heart beat simulation cavity 5 is communicated with a first pressure sensor 7, the water outlet of the first pressure sensor 7 is communicated with a compliance simulation tube 8, the compliance simulation tube 8 is a silicone tube, the water outlet of the compliance simulation tube 8 is communicated with a cardiovascular main artery model 9, the cardiovascular main artery model 9 is made of a fully transparent material in a 3D printing mode, the cardiovascular main artery model 9 comprises a left iliac artery 10, a right iliac artery 11 and other artery simulation tubes, the left iliac artery 10 and the right iliac artery 11 are both communicated with a second pressure sensor 12 and an electromagnetic flowmeter 13, the left iliac artery 10, the right iliac artery 11 and other artery simulation tubes are all communicated with a high-precision flow stop valve 15, the other artery simulation tubes comprise a brachiocephalic artery, a common carotid artery, a subclavian artery, an abdominal trunk artery, an superior mesenteric artery, a inferior mesenteric artery, a left renal artery and a right renal artery, the water outlets of the left iliac artery 10, the right iliac artery 11 and other artery simulation tubes are all communicated with the water storage barrel 1, first pressure sensor 7, second pressure sensor 12 and electromagnetic flowmeter 13 all communicate with data acquisition system 16, and Arduino control panel 14 and data acquisition system 16 all are connected with PC terminal 17 electricity.
The specific implementation process is as follows:
before the device is used, a certain amount of experiment simulation liquid (mixed liquid of 37% of glycerin and 0.9% of NaCl) is filled in a water storage barrel 1, the output quantity of a peristaltic pump 3 is adjusted to be 6L/min, the stretching frequency of a stretching motor 4 is adjusted according to experiment requirements, the frequency of a heart beat simulation cavity 5 pressed by a pressing plate is consistent with the heart beat frequency of a human body, amputation of different degrees is simulated by adjusting a high-precision flow stop valve 15, and then all electrical components are started to simulate the cardiovascular and hemodynamics characteristics after amputation of the lower limb; wherein, peristaltic pump 3 extracts the water in the water storage bucket 1 to realize flowing in aqueduct 2, and first pressure sensor 7 detects the pressure that heart beat simulation chamber 5 flows out the solution, and compliance simulation pipe 8 simulates the compliance of blood vessel, and second pressure sensor 12 and electromagnetic flowmeter 13 measure the liquid pressure and the flow of left iliac artery 10 and right iliac artery 11 respectively, and data acquisition system 16 gathers the pressure parameter and the flow parameter of entering its inboard rivers, and PC terminal 17 shows the rivers parameter.
The above description is only an example of the present invention, and the common general knowledge of the technical solutions or characteristics known in the solutions is not described herein too much. It should be noted that, for those skilled in the art, without departing from the technical solution of the present invention, several variations and modifications can be made, which should also be regarded as the protection scope of the present invention, and these will not affect the effect of the implementation of the present invention and the practicability of the patent. The scope of the claims of the present application shall be determined by the contents of the claims, and the description of the embodiments and the like in the specification shall be used to explain the contents of the claims.
Claims (7)
1. The utility model provides an experimental apparatus of simulation lower limb amputation back cardiovascular hemodynamic characteristic which characterized in that: including water storage bucket (1), flexible motor (4), data acquisition system (16) and PC terminal (17), water storage bucket (1) has peristaltic pump (3) through aqueduct (2) intercommunication, the delivery port intercommunication of peristaltic pump (3) has heart beat simulation chamber (5), flexible motor (4) are used for the cycle to press heart beat simulation chamber (5), the delivery port intercommunication of heart beat simulation chamber (5) has first pressure sensor (7), the delivery port intercommunication of first pressure sensor (7) has compliance simulation pipe (8), compliance simulation pipe (8) are the silicone tube, the delivery port intercommunication of compliance simulation pipe (8) has cardiovascular trunk artery model (9), cardiovascular trunk artery model (9) are including left iliac artery (10), right iliac artery (11) and other artery simulation pipes, the left iliac artery (10) and the right iliac artery (11) are all communicated with a second pressure sensor (12) and an electromagnetic flowmeter (13), the left iliac artery (10), the right iliac artery (11) and other artery simulation tubes are all communicated with a high-precision flow stop valve (15), the left iliac artery (10), the right iliac artery (11) and water outlets of other artery simulation tubes are all communicated with the water storage barrel (1), the first pressure sensor (7), the second pressure sensor (12) and the electromagnetic flowmeter (13) are all communicated with a data acquisition system (16), and the data acquisition system (16) is electrically connected with a PC terminal (17).
2. The device of claim 1, wherein the device is adapted to simulate cardiovascular hemodynamic characteristics following amputation of a lower limb: the output shaft of the telescopic motor (4) is connected with a pressing plate, the pressing plate is fixedly connected with the outer tube wall of the heart beat simulation cavity (5), and the diameter of the pressing plate is 1/3 the length of the heart beat simulation cavity (5).
3. The device of claim 1, wherein the device is adapted to simulate cardiovascular hemodynamic characteristics following amputation of a lower limb: the water inlet and the water outlet of the heart beat simulation cavity (5) are both communicated with a check valve (6), and the check valve (6) enables the solution in the heart beat simulation cavity (5) to flow from the peristaltic pump (3) to one side of the first pressure sensor (7).
4. The device of claim 1, wherein the device is adapted to simulate cardiovascular hemodynamic characteristics following amputation of a lower limb: the output quantity of the peristaltic pump (3) is 6L/min.
5. The device of claim 1, wherein the device is adapted to simulate cardiovascular hemodynamic characteristics following amputation of a lower limb: flexible motor (4) electricity is connected with Arduino control panel (14), Arduino control panel (14) with PC terminal (17) electricity is connected.
6. The device of claim 1, wherein the device is adapted to simulate cardiovascular hemodynamic characteristics following amputation of a lower limb: the cardiovascular main artery model (9) is manufactured in a 3D printing mode, and the cardiovascular main artery model (9) is completely transparent.
7. The device of claim 1, wherein the device is adapted to simulate cardiovascular hemodynamic characteristics following amputation of a lower limb: the other artery-simulated tubes include brachiocephalic trunk, common carotid artery, subclavian artery, celiac trunk, superior mesenteric artery, inferior mesenteric artery, left renal artery, and right renal artery.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202111152277.2A CN113916495A (en) | 2021-09-29 | 2021-09-29 | Experimental device for simulating cardiovascular hemodynamic characteristics after lower limb amputation |
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| CN202111152277.2A CN113916495A (en) | 2021-09-29 | 2021-09-29 | Experimental device for simulating cardiovascular hemodynamic characteristics after lower limb amputation |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110104651A1 (en) * | 2009-11-04 | 2011-05-05 | Sweeney Terrence E | Mechanical Model of the Cardiovascular System and Method of Demonstrating the Physiology of the Cardiovascular System |
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| CN210073105U (en) * | 2019-04-17 | 2020-02-14 | 石玄言 | Model for amputation training |
| CN111882962A (en) * | 2020-07-15 | 2020-11-03 | 福建工程学院 | Arteriovenous fistula in-vitro hemodynamics physical simulation model device |
-
2021
- 2021-09-29 CN CN202111152277.2A patent/CN113916495A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110104651A1 (en) * | 2009-11-04 | 2011-05-05 | Sweeney Terrence E | Mechanical Model of the Cardiovascular System and Method of Demonstrating the Physiology of the Cardiovascular System |
| CN102509503A (en) * | 2011-11-30 | 2012-06-20 | 中国人民解放军第二军医大学 | Adjustable human body aorta vessel model device |
| CN210073105U (en) * | 2019-04-17 | 2020-02-14 | 石玄言 | Model for amputation training |
| CN111882962A (en) * | 2020-07-15 | 2020-11-03 | 福建工程学院 | Arteriovenous fistula in-vitro hemodynamics physical simulation model device |
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